PMC:7461420 / 18054-18314 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7461420","sourcedb":"PMC","sourceid":"7461420","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7461420","text":"tor‐binding domain Xu et al. 49 identified two small molecules, TGG (2; Figure 4) and luteolin (3; Figure 4), that can bind avidly to the SARS‐CoV‐1 S2 protein and inhibit its entry into Vero E6 cells (EC50: 4.5 µM, 10.6 µM; respectively). Compounds 2 and 3 s","tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T104","span":{"begin":153,"end":160},"obj":"Body_part"},{"id":"T105","span":{"begin":196,"end":201},"obj":"Body_part"}],"attributes":[{"id":"A104","pred":"fma_id","subj":"T104","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A105","pred":"fma_id","subj":"T105","obj":"http://purl.org/sig/ont/fma/fma68646"},{"subj":"T104","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T105","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T101","span":{"begin":139,"end":143},"obj":"Disease"}],"attributes":[{"id":"A101","pred":"mondo_id","subj":"T101","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"subj":"T101","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T204","span":{"begin":150,"end":152},"obj":"http://purl.obolibrary.org/obo/CLO_0008922"},{"id":"T205","span":{"begin":150,"end":152},"obj":"http://purl.obolibrary.org/obo/CLO_0050052"},{"id":"T206","span":{"begin":188,"end":201},"obj":"http://purl.obolibrary.org/obo/CLO_0051719"}],"attributes":[{"subj":"T204","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T205","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T206","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T135","span":{"begin":54,"end":63},"obj":"Chemical"},{"id":"T136","span":{"begin":87,"end":95},"obj":"Chemical"},{"id":"T138","span":{"begin":150,"end":152},"obj":"Chemical"},{"id":"T139","span":{"begin":153,"end":160},"obj":"Chemical"}],"attributes":[{"id":"A135","pred":"chebi_id","subj":"T135","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A136","pred":"chebi_id","subj":"T136","obj":"http://purl.obolibrary.org/obo/CHEBI_15864"},{"id":"A137","pred":"chebi_id","subj":"T136","obj":"http://purl.obolibrary.org/obo/CHEBI_57545"},{"id":"A138","pred":"chebi_id","subj":"T138","obj":"http://purl.obolibrary.org/obo/CHEBI_29387"},{"id":"A139","pred":"chebi_id","subj":"T139","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"subj":"T135","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T136","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T138","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T139","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"587","span":{"begin":139,"end":147},"obj":"Species"},{"id":"593","span":{"begin":193,"end":195},"obj":"CellLine"}],"attributes":[{"id":"A587","pred":"tao:has_database_id","subj":"587","obj":"Tax:694009"},{"id":"A593","pred":"tao:has_database_id","subj":"593","obj":"CVCL:4582"},{"subj":"587","pred":"source","obj":"LitCovid-PubTator"},{"subj":"593","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T181","span":{"begin":29,"end":208},"obj":"Sentence"},{"id":"T182","span":{"begin":209,"end":240},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T181","pred":"source","obj":"LitCovid-sentences"},{"subj":"T182","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#93ece0","default":true},{"id":"LitCovid-PD-MONDO","color":"#ecc593"},{"id":"LitCovid-PD-CLO","color":"#ab93ec"},{"id":"LitCovid-PD-CHEBI","color":"#94ec93"},{"id":"LitCovid-PubTator","color":"#ec93ae"},{"id":"LitCovid-sentences","color":"#93c8ec"}]}]}}