PMC:7461420
Annnotations
LitCovid_Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 105151-105158 | https://glytoucan.org/Structures/Glycans/G15021LG | denotes | glucose |
| T2 | 109558-109563 | https://glytoucan.org/Structures/Glycans/G00052MO | denotes | Ley's |
| T89985 | 6361-6372 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
| T64680 | 7033-7044 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
| T3 | 7085-7096 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T1 | 99885-99889 | Body_part | denotes | Shin | http://purl.org/sig/ont/fma/fma24985 |
| T2 | 100460-100468 | Body_part | denotes | tyrosine | http://purl.org/sig/ont/fma/fma82768 |
| T3 | 102339-102342 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
| T4 | 104663-104676 | Body_part | denotes | cell membrane | http://purl.org/sig/ont/fma/fma63841 |
| T5 | 104663-104667 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T6 | 105151-105158 | Body_part | denotes | glucose | http://purl.org/sig/ont/fma/fma82743 |
| T7 | 105169-105176 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T8 | 109722-109731 | Body_part | denotes | G‐protein | http://purl.org/sig/ont/fma/fma61788 |
| T9 | 110109-110118 | Body_part | denotes | G protein | http://purl.org/sig/ont/fma/fma61788 |
| T10 | 110861-110866 | Body_part | denotes | heart | http://purl.org/sig/ont/fma/fma7088 |
| T11 | 111025-111029 | Body_part | denotes | Shin | http://purl.org/sig/ont/fma/fma24985 |
| T66365 | 207-213 | Body_part | denotes | kidney | http://purl.org/sig/ont/fma/fma7203 |
| T52326 | 215-220 | Body_part | denotes | heart | http://purl.org/sig/ont/fma/fma7088 |
| T73963 | 222-227 | Body_part | denotes | brain | http://purl.org/sig/ont/fma/fma50801 |
| T56377 | 233-243 | Body_part | denotes | intestinal | http://purl.org/sig/ont/fma/fma7199 |
| T49869 | 1021-1033 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T19419 | 1151-1159 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T54908 | 1165-1168 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T51001 | 1179-1182 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T58222 | 1204-1207 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T96720 | 1655-1666 | Body_part | denotes | interleukin | http://purl.org/sig/ont/fma/fma86578 |
| T64809 | 1930-1933 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T12 | 1944-1947 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T13 | 2089-2095 | Body_part | denotes | serine | http://purl.org/sig/ont/fma/fma82764 |
| T14 | 2227-2237 | Body_part | denotes | intestinal | http://purl.org/sig/ont/fma/fma7199 |
| T15 | 5035-5038 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T16 | 5075-5078 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T17 | 5079-5086 | Body_part | denotes | genomes | http://purl.org/sig/ont/fma/fma84116 |
| T18 | 5158-5164 | Body_part | denotes | genome | http://purl.org/sig/ont/fma/fma84116 |
| T19 | 5183-5194 | Body_part | denotes | nucleotides | http://purl.org/sig/ont/fma/fma82740 |
| T20 | 5274-5282 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T21 | 5471-5474 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T22 | 5480-5488 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T23 | 5503-5506 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T24 | 5542-5546 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T25 | 5582-5595 | Body_part | denotes | glycoproteins | http://purl.org/sig/ont/fma/fma62925 |
| T26 | 5833-5845 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T27 | 5900-5904 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T28 | 5915-5919 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T29 | 5966-5973 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
| T30 | 6013-6020 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T31 | 6966-6970 | Body_part | denotes | Palm | http://purl.org/sig/ont/fma/fma24920 |
| T32 | 7127-7131 | Body_part | denotes | Palm | http://purl.org/sig/ont/fma/fma24920 |
| T33 | 7682-7689 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T34 | 7874-7880 | Body_part | denotes | cell's | http://purl.org/sig/ont/fma/fma68646 |
| T35 | 7899-7905 | Body_part | denotes | serine | http://purl.org/sig/ont/fma/fma82764 |
| T36 | 7996-8011 | Body_part | denotes | cell's membrane | http://purl.org/sig/ont/fma/fma63841 |
| T37 | 8091-8097 | Body_part | denotes | cell's | http://purl.org/sig/ont/fma/fma68646 |
| T38 | 8098-8107 | Body_part | denotes | cytoplasm | http://purl.org/sig/ont/fma/fma66835 |
| T39 | 8144-8147 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T40 | 8293-8301 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T41 | 8506-8514 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T42 | 8697-8705 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T43 | 8721-8724 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T44 | 8735-8738 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T45 | 8802-8805 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T46 | 8831-8839 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T47 | 8851-8863 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T48 | 8878-8886 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T49 | 8897-8905 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T50 | 8932-8940 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T51 | 8984-8987 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T52 | 9049-9052 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T53 | 9161-9169 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T54 | 9177-9198 | Body_part | denotes | endoplasmic reticulum | http://purl.org/sig/ont/fma/fma63842 |
| T55 | 9209-9217 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T56 | 9230-9233 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T57 | 9277-9292 | Body_part | denotes | Golgi apparatus | http://purl.org/sig/ont/fma/fma63843 |
| T58 | 9360-9365 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T59 | 9441-9446 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T60 | 9580-9589 | Body_part | denotes | cytokines | http://purl.org/sig/ont/fma/fma84050 |
| T61 | 9594-9604 | Body_part | denotes | chemokines | http://purl.org/sig/ont/fma/fma241981 |
| T62 | 9610-9623 | Body_part | denotes | interleukin 1 | http://purl.org/sig/ont/fma/fma86583 |
| T63 | 9610-9621 | Body_part | denotes | interleukin | http://purl.org/sig/ont/fma/fma86578 |
| T64 | 9625-9629 | Body_part | denotes | IL‐1 | http://purl.org/sig/ont/fma/fma86583 |
| T65 | 9719-9724 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T66 | 9946-9953 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T67 | 9954-9961 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T68 | 10042-10050 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T69 | 10137-10145 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T70 | 10156-10168 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T71 | 10722-10729 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T72 | 10887-10893 | Body_part | denotes | genome | http://purl.org/sig/ont/fma/fma84116 |
| T73 | 11044-11051 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T74 | 11058-11068 | Body_part | denotes | nucleotide | http://purl.org/sig/ont/fma/fma82740 |
| T75 | 11181-11188 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T76 | 11222-11229 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T77 | 12146-12152 | Body_part | denotes | genome | http://purl.org/sig/ont/fma/fma84116 |
| T78 | 12378-12384 | Body_part | denotes | genome | http://purl.org/sig/ont/fma/fma84116 |
| T79 | 12729-12736 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T80 | 12809-12816 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T81 | 13025-13029 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T82 | 14233-14237 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T83 | 14491-14502 | Body_part | denotes | amino acids | http://purl.org/sig/ont/fma/fma82739 |
| T84 | 14774-14781 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T85 | 15133-15140 | Body_part | denotes | glycine | http://purl.org/sig/ont/fma/fma82753 |
| T86 | 15603-15610 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T87 | 15717-15724 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T88 | 15854-15866 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T89 | 15897-15909 | Body_part | denotes | cell surface | http://purl.org/sig/ont/fma/fma67653 |
| T90 | 15897-15901 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T91 | 16042-16056 | Body_part | denotes | alveolar cells | http://purl.org/sig/ont/fma/fma62499 |
| T92 | 16051-16056 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T93 | 16070-16075 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
| T94 | 16316-16321 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T95 | 16452-16457 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T96 | 16544-16555 | Body_part | denotes | amino acids | http://purl.org/sig/ont/fma/fma82739 |
| T97 | 16614-16619 | Body_part | denotes | helix | http://purl.org/sig/ont/fma/fma60992 |
| T98 | 16679-16686 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T99 | 16752-16755 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
| T100 | 16965-16973 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T101 | 17212-17219 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T102 | 17390-17394 | Body_part | denotes | hand | http://purl.org/sig/ont/fma/fma9712 |
| T103 | 17450-17458 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T104 | 18207-18214 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T105 | 18250-18255 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T106 | 19086-19091 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T107 | 19170-19177 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T108 | 19261-19266 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T109 | 19607-19612 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T110 | 19656-19667 | Body_part | denotes | endothelium | http://purl.org/sig/ont/fma/fma63916 |
| T111 | 19680-19684 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T112 | 19709-19734 | Body_part | denotes | alveolar epithelial cells | http://purl.org/sig/ont/fma/fma62499 |
| T113 | 19729-19734 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T114 | 19779-19786 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T115 | 19818-19828 | Body_part | denotes | amino acid | http://purl.org/sig/ont/fma/fma82739 |
| T116 | 19881-19888 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T117 | 19907-19914 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T118 | 20033-20037 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T119 | 20091-20098 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T120 | 20180-20185 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
| T121 | 20570-20574 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T122 | 21105-21109 | Body_part | denotes | hand | http://purl.org/sig/ont/fma/fma9712 |
| T123 | 21176-21186 | Body_part | denotes | amino acid | http://purl.org/sig/ont/fma/fma82739 |
| T124 | 21231-21241 | Body_part | denotes | amino acid | http://purl.org/sig/ont/fma/fma82739 |
| T125 | 22170-22184 | Body_part | denotes | late endosomal | http://purl.org/sig/ont/fma/fma67467 |
| T126 | 22189-22198 | Body_part | denotes | lysosomal | http://purl.org/sig/ont/fma/fma63836 |
| T127 | 22252-22261 | Body_part | denotes | endosomes | http://purl.org/sig/ont/fma/fma67180 |
| T128 | 22265-22274 | Body_part | denotes | lysosomes | http://purl.org/sig/ont/fma/fma63836 |
| T129 | 22347-22351 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T130 | 22470-22479 | Body_part | denotes | cytokines | http://purl.org/sig/ont/fma/fma84050 |
| T131 | 22810-22815 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T132 | 22884-22900 | Body_part | denotes | epithelial cells | http://purl.org/sig/ont/fma/fma66768 |
| T133 | 22895-22900 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T134 | 23396-23401 | Body_part | denotes | heart | http://purl.org/sig/ont/fma/fma7088 |
| T135 | 24688-24691 | Body_part | denotes | arm | http://purl.org/sig/ont/fma/fma24890 |
| T136 | 27079-27083 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T137 | 27125-27132 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T138 | 27162-27167 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T139 | 27345-27349 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T140 | 27889-27894 | Body_part | denotes | heart | http://purl.org/sig/ont/fma/fma7088 |
| T141 | 28091-28096 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
| T142 | 28168-28173 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
| T143 | 28313-28318 | Body_part | denotes | joint | http://purl.org/sig/ont/fma/fma7490 |
| T144 | 28795-28799 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T145 | 28873-28878 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T146 | 28888-28896 | Body_part | denotes | clathrin | http://purl.org/sig/ont/fma/fma62262 |
| T147 | 28898-28907 | Body_part | denotes | endosomal | http://purl.org/sig/ont/fma/fma67180 |
| T148 | 29023-29031 | Body_part | denotes | clathrin | http://purl.org/sig/ont/fma/fma62262 |
| T149 | 29079-29086 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T150 | 29169-29183 | Body_part | denotes | late endosomes | http://purl.org/sig/ont/fma/fma67467 |
| T151 | 29206-29214 | Body_part | denotes | endosome | http://purl.org/sig/ont/fma/fma67180 |
| T152 | 29290-29304 | Body_part | denotes | late endosomes | http://purl.org/sig/ont/fma/fma67467 |
| T153 | 29309-29318 | Body_part | denotes | lysosomes | http://purl.org/sig/ont/fma/fma63836 |
| T154 | 29354-29361 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T155 | 29473-29477 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T156 | 29518-29523 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T157 | 29612-29621 | Body_part | denotes | endosomal | http://purl.org/sig/ont/fma/fma67180 |
| T158 | 29738-29745 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T159 | 29791-29798 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T160 | 30050-30055 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T161 | 30069-30075 | Body_part | denotes | serine | http://purl.org/sig/ont/fma/fma82764 |
| T162 | 30177-30202 | Body_part | denotes | neurotransmitter receptor | http://purl.org/sig/ont/fma/fma67184 |
| T163 | 30362-30369 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T164 | 30409-30417 | Body_part | denotes | clathrin | http://purl.org/sig/ont/fma/fma62262 |
| T165 | 30632-30648 | Body_part | denotes | Neurotransmitter | http://purl.org/sig/ont/fma/fma302832 |
| T166 | 30670-30678 | Body_part | denotes | clathrin | http://purl.org/sig/ont/fma/fma62262 |
| T167 | 30755-30761 | Body_part | denotes | serine | http://purl.org/sig/ont/fma/fma82764 |
| T168 | 30959-30966 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T169 | 30976-30980 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T170 | 31087-31096 | Body_part | denotes | endosomal | http://purl.org/sig/ont/fma/fma67180 |
| T171 | 31345-31351 | Body_part | denotes | serine | http://purl.org/sig/ont/fma/fma82764 |
| T172 | 31625-31630 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T173 | 31757-31765 | Body_part | denotes | cysteine | http://purl.org/sig/ont/fma/fma82751 |
| T174 | 31799-31805 | Body_part | denotes | tissue | http://purl.org/sig/ont/fma/fma9637 |
| T175 | 31908-31914 | Body_part | denotes | tissue | http://purl.org/sig/ont/fma/fma9637 |
| T176 | 32062-32074 | Body_part | denotes | glycopeptide | http://purl.org/sig/ont/fma/fma82784 |
| T177 | 32638-32646 | Body_part | denotes | cysteine | http://purl.org/sig/ont/fma/fma82751 |
| T178 | 32730-32737 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T179 | 32775-32789 | Body_part | denotes | late endosomes | http://purl.org/sig/ont/fma/fma67467 |
| T180 | 32863-32867 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T181 | 33682-33688 | Body_part | denotes | kidney | http://purl.org/sig/ont/fma/fma7203 |
| T182 | 33694-33699 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T183 | 33765-33782 | Body_part | denotes | endothelial cells | http://purl.org/sig/ont/fma/fma66772 |
| T184 | 33777-33782 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T185 | 33930-33934 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T186 | 34112-34117 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T187 | 34417-34421 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T188 | 34448-34452 | Body_part | denotes | hand | http://purl.org/sig/ont/fma/fma9712 |
| T189 | 34686-34693 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T190 | 34769-34776 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T191 | 34820-34825 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T192 | 35010-35023 | Body_part | denotes | cell membrane | http://purl.org/sig/ont/fma/fma63841 |
| T193 | 35010-35014 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T194 | 35304-35309 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T195 | 36039-36047 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T196 | 36059-36062 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T197 | 36071-36079 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T198 | 36358-36366 | Body_part | denotes | cysteine | http://purl.org/sig/ont/fma/fma82751 |
| T199 | 36680-36688 | Body_part | denotes | cysteine | http://purl.org/sig/ont/fma/fma82751 |
| T200 | 36738-36747 | Body_part | denotes | histidine | http://purl.org/sig/ont/fma/fma82755 |
| T201 | 38010-38018 | Body_part | denotes | cysteine | http://purl.org/sig/ont/fma/fma82751 |
| T202 | 38333-38343 | Body_part | denotes | amino acid | http://purl.org/sig/ont/fma/fma82739 |
| T203 | 39123-39130 | Body_part | denotes | leucine | http://purl.org/sig/ont/fma/fma82757 |
| T204 | 40234-40238 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T205 | 40507-40513 | Body_part | denotes | serine | http://purl.org/sig/ont/fma/fma82764 |
| T206 | 41007-41011 | Body_part | denotes | hand | http://purl.org/sig/ont/fma/fma9712 |
| T207 | 41149-41157 | Body_part | denotes | backbone | http://purl.org/sig/ont/fma/fma13478 |
| T208 | 41481-41488 | Body_part | denotes | leucine | http://purl.org/sig/ont/fma/fma82757 |
| T209 | 41561-41574 | Body_part | denotes | phenylalanine | http://purl.org/sig/ont/fma/fma82754 |
| T210 | 41691-41697 | Body_part | denotes | valine | http://purl.org/sig/ont/fma/fma82766 |
| T211 | 41912-41916 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T212 | 43062-43068 | Body_part | denotes | genome | http://purl.org/sig/ont/fma/fma84116 |
| T213 | 44443-44451 | Body_part | denotes | cysteine | http://purl.org/sig/ont/fma/fma82751 |
| T214 | 44508-44516 | Body_part | denotes | cysteine | http://purl.org/sig/ont/fma/fma82751 |
| T215 | 44732-44740 | Body_part | denotes | cysteine | http://purl.org/sig/ont/fma/fma82751 |
| T216 | 45054-45058 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T217 | 45135-45141 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T218 | 45199-45205 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T219 | 45502-45510 | Body_part | denotes | cysteine | http://purl.org/sig/ont/fma/fma82751 |
| T220 | 45573-45580 | Body_part | denotes | leucine | http://purl.org/sig/ont/fma/fma82757 |
| T221 | 46023-46029 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T222 | 46094-46099 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T223 | 46443-46456 | Body_part | denotes | cell‐membrane | http://purl.org/sig/ont/fma/fma63841 |
| T224 | 46443-46447 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T225 | 46818-46823 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T226 | 47670-47679 | Body_part | denotes | histidine | http://purl.org/sig/ont/fma/fma82755 |
| T227 | 50157-50161 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T228 | 50630-50638 | Body_part | denotes | backbone | http://purl.org/sig/ont/fma/fma13478 |
| T229 | 50808-50816 | Body_part | denotes | cysteine | http://purl.org/sig/ont/fma/fma82751 |
| T230 | 51088-51096 | Body_part | denotes | cysteine | http://purl.org/sig/ont/fma/fma82751 |
| T231 | 51524-51528 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T232 | 53198-53203 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T233 | 53282-53287 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T234 | 53442-53446 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T235 | 54100-54106 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T236 | 54216-54222 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T237 | 54260-54266 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T238 | 54267-54275 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T239 | 54511-54517 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T240 | 54608-54614 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T241 | 54842-54848 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T242 | 54849-54856 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T243 | 55485-55490 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T244 | 55655-55672 | Body_part | denotes | cellular membrane | http://purl.org/sig/ont/fma/fma63841 |
| T245 | 55699-55703 | Body_part | denotes | hand | http://purl.org/sig/ont/fma/fma9712 |
| T246 | 55793-55799 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T247 | 55800-55807 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T248 | 55899-55903 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T249 | 56523-56531 | Body_part | denotes | cysteine | http://purl.org/sig/ont/fma/fma82751 |
| T250 | 57636-57642 | Body_part | denotes | serine | http://purl.org/sig/ont/fma/fma82764 |
| T251 | 57646-57654 | Body_part | denotes | cysteine | http://purl.org/sig/ont/fma/fma82751 |
| T252 | 58239-58247 | Body_part | denotes | cysteine | http://purl.org/sig/ont/fma/fma82751 |
| T253 | 58493-58501 | Body_part | denotes | backbone | http://purl.org/sig/ont/fma/fma13478 |
| T254 | 58502-58512 | Body_part | denotes | amino acid | http://purl.org/sig/ont/fma/fma82739 |
| T255 | 59211-59217 | Body_part | denotes | valine | http://purl.org/sig/ont/fma/fma82766 |
| T256 | 59526-59534 | Body_part | denotes | backbone | http://purl.org/sig/ont/fma/fma13478 |
| T257 | 59578-59585 | Body_part | denotes | leucine | http://purl.org/sig/ont/fma/fma82757 |
| T258 | 60052-60060 | Body_part | denotes | backbone | http://purl.org/sig/ont/fma/fma13478 |
| T259 | 60963-60967 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T260 | 62521-62524 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
| T261 | 62728-62731 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
| T262 | 62929-62932 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
| T263 | 62955-62958 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
| T264 | 63329-63333 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T265 | 64414-64418 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T266 | 64854-64859 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T267 | 68494-68505 | Body_part | denotes | pyrimidines | http://purl.org/sig/ont/fma/fma82773 |
| T268 | 68996-69006 | Body_part | denotes | pyrimidine | http://purl.org/sig/ont/fma/fma82773 |
| T269 | 70189-70194 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T270 | 74341-74345 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T271 | 74420-74429 | Body_part | denotes | serotonin | http://purl.org/sig/ont/fma/fma67245 |
| T272 | 76135-76143 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T273 | 76336-76340 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
| T274 | 76463-76471 | Body_part | denotes | cysteine | http://purl.org/sig/ont/fma/fma82751 |
| T275 | 77677-77682 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T276 | 78137-78141 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T277 | 78427-78432 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T278 | 78852-78856 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T279 | 79061-79065 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T280 | 79333-79337 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T281 | 81360-81368 | Body_part | denotes | cysteine | http://purl.org/sig/ont/fma/fma82751 |
| T282 | 81508-81511 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T283 | 81585-81588 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T284 | 81635-81640 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T285 | 81700-81703 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T286 | 81751-81754 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T287 | 81768-81771 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T288 | 81878-81881 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T289 | 82015-82021 | Body_part | denotes | genome | http://purl.org/sig/ont/fma/fma84116 |
| T290 | 82038-82042 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T291 | 82070-82078 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T292 | 82432-82435 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T293 | 82963-82966 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T294 | 82977-82980 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T295 | 83085-83092 | Body_part | denotes | adenine | http://purl.org/sig/ont/fma/fma82774 |
| T296 | 83266-83271 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T297 | 83448-83455 | Body_part | denotes | adenine | http://purl.org/sig/ont/fma/fma82774 |
| T298 | 83505-83508 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T299 | 83888-83891 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T300 | 83963-83966 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T301 | 84180-84183 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T302 | 84473-84477 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T303 | 84797-84801 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T304 | 85010-85015 | Body_part | denotes | sugar | http://purl.org/sig/ont/fma/fma82737 |
| T305 | 85644-85647 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T306 | 86110-86113 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T307 | 86182-86189 | Body_part | denotes | guanine | http://purl.org/sig/ont/fma/fma82775 |
| T308 | 86328-86331 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T309 | 88642-88647 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
| T310 | 89020-89025 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T311 | 89388-89393 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T312 | 89467-89476 | Body_part | denotes | endosomal | http://purl.org/sig/ont/fma/fma67180 |
| T313 | 89539-89544 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T314 | 89986-89995 | Body_part | denotes | serotonin | http://purl.org/sig/ont/fma/fma67245 |
| T315 | 90147-90157 | Body_part | denotes | calmodulin | http://purl.org/sig/ont/fma/fma62343 |
| T316 | 90937-90940 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
| T317 | 91017-91020 | Body_part | denotes | DNA | http://purl.org/sig/ont/fma/fma74412 |
| T318 | 91065-91073 | Body_part | denotes | Estrogen | http://purl.org/sig/ont/fma/fma83376 |
| T319 | 91119-91127 | Body_part | denotes | Estrogen | http://purl.org/sig/ont/fma/fma83376 |
| T320 | 91277-91284 | Body_part | denotes | Protein | http://purl.org/sig/ont/fma/fma67257 |
| T321 | 91334-91341 | Body_part | denotes | Protein | http://purl.org/sig/ont/fma/fma67257 |
| T322 | 91395-91402 | Body_part | denotes | Protein | http://purl.org/sig/ont/fma/fma67257 |
| T323 | 91447-91463 | Body_part | denotes | Neurotransmitter | http://purl.org/sig/ont/fma/fma302832 |
| T324 | 91502-91518 | Body_part | denotes | Neurotransmitter | http://purl.org/sig/ont/fma/fma302832 |
| T325 | 91554-91570 | Body_part | denotes | Neurotransmitter | http://purl.org/sig/ont/fma/fma302832 |
| T326 | 91609-91625 | Body_part | denotes | Neurotransmitter | http://purl.org/sig/ont/fma/fma302832 |
| T327 | 91663-91679 | Body_part | denotes | Neurotransmitter | http://purl.org/sig/ont/fma/fma302832 |
| T328 | 91717-91733 | Body_part | denotes | Neurotransmitter | http://purl.org/sig/ont/fma/fma302832 |
| T329 | 91769-91785 | Body_part | denotes | Neurotransmitter | http://purl.org/sig/ont/fma/fma302832 |
| T330 | 91826-91842 | Body_part | denotes | Neurotransmitter | http://purl.org/sig/ont/fma/fma302832 |
| T331 | 91885-91901 | Body_part | denotes | Neurotransmitter | http://purl.org/sig/ont/fma/fma302832 |
| T332 | 91938-91954 | Body_part | denotes | Neurotransmitter | http://purl.org/sig/ont/fma/fma302832 |
| T333 | 91991-92007 | Body_part | denotes | Neurotransmitter | http://purl.org/sig/ont/fma/fma302832 |
| T334 | 92482-92489 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T335 | 92600-92603 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
| T336 | 93107-93123 | Body_part | denotes | neurotransmitter | http://purl.org/sig/ont/fma/fma302832 |
| T337 | 93217-93220 | Body_part | denotes | DNA | http://purl.org/sig/ont/fma/fma74412 |
| T338 | 93366-93374 | Body_part | denotes | estrogen | http://purl.org/sig/ont/fma/fma83376 |
| T339 | 93709-93717 | Body_part | denotes | endosome | http://purl.org/sig/ont/fma/fma67180 |
| T340 | 94068-94073 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T341 | 94162-94168 | Body_part | denotes | lysine | http://purl.org/sig/ont/fma/fma82758 |
| T342 | 94444-94449 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T343 | 94787-94792 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T344 | 95877-95881 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T345 | 96194-96198 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T346 | 96686-96691 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
| T347 | 96879-96897 | Body_part | denotes | pulmonary arterial | http://purl.org/sig/ont/fma/fma66326 |
| T348 | 97008-97013 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
| T349 | 97014-97019 | Body_part | denotes | lipid | http://purl.org/sig/ont/fma/fma67264 |
| T350 | 97098-97103 | Body_part | denotes | lipid | http://purl.org/sig/ont/fma/fma67264 |
| T351 | 97124-97127 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
| T352 | 97228-97233 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T353 | 97478-97481 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
| T354 | 97558-97563 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
| T355 | 99366-99374 | Body_part | denotes | clathrin | http://purl.org/sig/ont/fma/fma62262 |
| T356 | 99404-99412 | Body_part | denotes | clathrin | http://purl.org/sig/ont/fma/fma62262 |
| T357 | 99482-99486 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T358 | 99807-99810 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 207-213 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
| T2 | 215-220 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/UBERON_0000948 |
| T3 | 222-227 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955 |
| T4 | 16614-16619 | Body_part | denotes | helix | http://purl.obolibrary.org/obo/UBERON_0002488 |
| T5 | 17390-17394 | Body_part | denotes | hand | http://purl.obolibrary.org/obo/UBERON_0002398 |
| T6 | 19656-19667 | Body_part | denotes | endothelium | http://purl.obolibrary.org/obo/UBERON_0001986 |
| T7 | 19680-19684 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T8 | 20033-20037 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T9 | 20180-20185 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T10 | 20570-20574 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T11 | 20838-20862 | Body_part | denotes | renin‐angiotensin system | http://purl.obolibrary.org/obo/UBERON_0018229 |
| T12 | 20970-20994 | Body_part | denotes | renin‐angiotensin system | http://purl.obolibrary.org/obo/UBERON_0018229 |
| T13 | 21105-21109 | Body_part | denotes | hand | http://purl.obolibrary.org/obo/UBERON_0002398 |
| T14 | 23396-23401 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/UBERON_0000948 |
| T15 | 24688-24691 | Body_part | denotes | arm | http://purl.obolibrary.org/obo/UBERON_0001460 |
| T16 | 27889-27894 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/UBERON_0000948 |
| T17 | 28168-28173 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T18 | 28795-28799 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T19 | 31799-31805 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
| T20 | 31908-31914 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
| T21 | 33682-33688 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
| T22 | 34448-34452 | Body_part | denotes | hand | http://purl.obolibrary.org/obo/UBERON_0002398 |
| T23 | 41007-41011 | Body_part | denotes | hand | http://purl.obolibrary.org/obo/UBERON_0002398 |
| T24 | 55699-55703 | Body_part | denotes | hand | http://purl.obolibrary.org/obo/UBERON_0002398 |
| T25 | 55899-55903 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T26 | 84797-84801 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T27 | 88642-88647 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
| T28 | 95877-95881 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T29 | 96194-96198 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T30 | 96686-96696 | Body_part | denotes | blood clot | http://purl.obolibrary.org/obo/UBERON_0010210 |
| T31 | 96686-96691 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T32 | 96879-96897 | Body_part | denotes | pulmonary arterial | http://purl.obolibrary.org/obo/UBERON_0002012 |
| T33 | 97008-97013 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T34 | 97558-97563 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
| T35 | 110861-110866 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/UBERON_0000948 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 244-254 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T2 | 401-434 | Disease | denotes | severe‐acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T3 | 436-440 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T4 | 498-502 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T5 | 737-747 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T6 | 874-878 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T7 | 896-900 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T8 | 1313-1316 | Disease | denotes | ADA | http://purl.obolibrary.org/obo/MONDO_0007064 |
| T9 | 1353-1356 | Disease | denotes | ARB | http://purl.obolibrary.org/obo/MONDO_0012733 |
| T10 | 1386-1390 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T11 | 1391-1426 | Disease | denotes | acute respiratory distress syndrome | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T12 | 1397-1426 | Disease | denotes | respiratory distress syndrome | http://purl.obolibrary.org/obo/MONDO_0009971 |
| T13 | 1570-1573 | Disease | denotes | HTS | http://purl.obolibrary.org/obo/MONDO_0011549 |
| T14 | 1731-1740 | Disease | denotes | hepatitis | http://purl.obolibrary.org/obo/MONDO_0002251 |
| T15 | 1959-1963 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T16 | 1964-1997 | Disease | denotes | severe‐acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T17 | 2046-2061 | Disease | denotes | gastroenteritis | http://purl.obolibrary.org/obo/MONDO_0002269 |
| T18 | 2238-2248 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T19 | 2742-2764 | Disease | denotes | respiratory infections | http://purl.obolibrary.org/obo/MONDO_0024355 |
| T20 | 2925-2934 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T21 | 3177-3210 | Disease | denotes | severe‐acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T22 | 3212-3216 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T23 | 3274-3278 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T24 | 3286-3294 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T25 | 3520-3530 | Disease | denotes | infectious | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T26 | 3726-3730 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T27 | 4001-4005 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T28 | 4112-4121 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T29 | 4203-4207 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T30 | 4607-4616 | Disease | denotes | Infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T31 | 4838-4842 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T32 | 4850-4854 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T33 | 5147-5151 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T34 | 5762-5771 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T35 | 6127-6131 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T36 | 6139-6143 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T37 | 6407-6416 | Disease | denotes | Infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T38 | 6454-6458 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T39 | 6566-6575 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T40 | 6578-6582 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T41 | 6590-6637 | Disease | denotes | severe acute respiratory syndrome coronavirus 2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T42 | 6590-6623 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T43 | 7103-7107 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T44 | 7174-7178 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T45 | 7249-7253 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T46 | 7441-7449 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T47 | 9929-9933 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T48 | 9995-9999 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T49 | 10337-10341 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T50 | 10897-10901 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T51 | 10972-10976 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T52 | 11031-11035 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T53 | 11168-11172 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T54 | 11241-11245 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T55 | 11499-11508 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T56 | 11558-11562 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T57 | 11578-11582 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T58 | 11665-11669 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T59 | 11682-11686 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T60 | 11734-11738 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T61 | 11755-11759 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T62 | 11829-11833 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T63 | 11850-11854 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T64 | 11883-11887 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T65 | 11904-11908 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T66 | 11962-11966 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T67 | 11974-12021 | Disease | denotes | severe acute respiratory syndrome coronavirus 2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T68 | 11974-12007 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T69 | 12165-12169 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T70 | 12266-12270 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T71 | 12327-12331 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T72 | 12436-12440 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T73 | 12448-12452 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T74 | 12595-12599 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T75 | 12745-12749 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T76 | 12770-12774 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T77 | 12866-12870 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T78 | 12973-12977 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T79 | 13274-13278 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T80 | 13453-13457 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T81 | 13613-13617 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T82 | 13628-13632 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T83 | 13688-13692 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T84 | 13720-13724 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T85 | 13862-13866 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T86 | 13874-13878 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T87 | 14906-14910 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T88 | 15052-15056 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T89 | 15246-15250 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T90 | 15409-15413 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T91 | 15462-15466 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T92 | 16281-16290 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T93 | 16596-16600 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T94 | 17009-17014 | Disease | denotes | Ebola | http://purl.obolibrary.org/obo/MONDO_0005737 |
| T95 | 17056-17072 | Disease | denotes | immunodeficiency | http://purl.obolibrary.org/obo/MONDO_0021094 |
| T96 | 17087-17103 | Disease | denotes | immunodeficiency | http://purl.obolibrary.org/obo/MONDO_0021094 |
| T97 | 17184-17188 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T98 | 17199-17203 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T99 | 17326-17330 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T100 | 17722-17726 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T101 | 18193-18197 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T102 | 18764-18768 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T103 | 18895-18899 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T104 | 19031-19035 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T105 | 19373-19377 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T106 | 19420-19424 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T107 | 19449-19453 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T108 | 19542-19551 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T109 | 19553-19557 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T110 | 19740-19744 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T111 | 19792-19796 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T112 | 19868-19872 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T113 | 19894-19898 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T114 | 20480-20492 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T115 | 20523-20558 | Disease | denotes | acute respiratory distress syndrome | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T116 | 20529-20558 | Disease | denotes | respiratory distress syndrome | http://purl.obolibrary.org/obo/MONDO_0009971 |
| T117 | 20560-20564 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T118 | 20609-20613 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T119 | 20623-20627 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T120 | 21429-21452 | Disease | denotes | cardiovascular diseases | http://purl.obolibrary.org/obo/MONDO_0004995 |
| T121 | 21834-21838 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T122 | 21903-21907 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T123 | 21913-21946 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T124 | 22060-22067 | Disease | denotes | malaria | http://purl.obolibrary.org/obo/MONDO_0005136 |
| T125 | 22072-22081 | Disease | denotes | amebiasis | http://purl.obolibrary.org/obo/MONDO_0005644 |
| T126 | 22552-22556 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T127 | 22611-22615 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T128 | 22637-22641 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T129 | 22673-22677 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T130 | 22755-22759 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T131 | 22963-22967 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T132 | 22974-22983 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T133 | 23054-23058 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T134 | 23159-23163 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T135 | 23187-23191 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T136 | 23332-23340 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T137 | 23396-23409 | Disease | denotes | heart disease | http://purl.obolibrary.org/obo/MONDO_0005267 |
| T138 | 23413-23421 | Disease | denotes | diabetes | http://purl.obolibrary.org/obo/MONDO_0005015 |
| T139 | 23723-23731 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T140 | 23843-23847 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T141 | 24017-24021 | Disease | denotes | Zika | http://purl.obolibrary.org/obo/MONDO_0018661 |
| T142 | 24026-24031 | Disease | denotes | Ebola | http://purl.obolibrary.org/obo/MONDO_0005737 |
| T143 | 24169-24185 | Disease | denotes | viral infections | http://purl.obolibrary.org/obo/MONDO_0005108 |
| T144 | 25030-25038 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T145 | 25148-25156 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T146 | 25227-25235 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T147 | 25600-25610 | Disease | denotes | arrhythmia | http://purl.obolibrary.org/obo/MONDO_0007263 |
| T148 | 25752-25760 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T149 | 25881-25900 | Disease | denotes | autoimmune diseases | http://purl.obolibrary.org/obo/MONDO_0007179 |
| T150 | 25905-25912 | Disease | denotes | malaria | http://purl.obolibrary.org/obo/MONDO_0005136 |
| T151 | 26873-26877 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T152 | 27288-27297 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T153 | 27438-27442 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T154 | 27484-27488 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T155 | 27546-27554 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T156 | 27589-27593 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T157 | 27692-27695 | Disease | denotes | ARB | http://purl.obolibrary.org/obo/MONDO_0012733 |
| T158 | 27707-27715 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T159 | 27889-27902 | Disease | denotes | heart disease | http://purl.obolibrary.org/obo/MONDO_0005267 |
| T160 | 28163-28182 | Disease | denotes | high blood pressure | http://purl.obolibrary.org/obo/MONDO_0005044 |
| T161 | 28247-28255 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T162 | 28365-28368 | Disease | denotes | AHA | http://purl.obolibrary.org/obo/MONDO_0020108 |
| T163 | 28527-28530 | Disease | denotes | ARB | http://purl.obolibrary.org/obo/MONDO_0012733 |
| T164 | 28650-28654 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T165 | 28795-28808 | Disease | denotes | lung diseases | http://purl.obolibrary.org/obo/MONDO_0005275 |
| T166 | 29440-29444 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T167 | 29939-29949 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T168 | 30023-30027 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T169 | 30323-30327 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T170 | 30499-30510 | Disease | denotes | hepatitis C | http://purl.obolibrary.org/obo/MONDO_0005231 |
| T171 | 30499-30508 | Disease | denotes | hepatitis | http://purl.obolibrary.org/obo/MONDO_0002251 |
| T172 | 30518-30528 | Disease | denotes | infectious | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T173 | 30529-30539 | Disease | denotes | bronchitis | http://purl.obolibrary.org/obo/MONDO_0003781 |
| T174 | 30564-30573 | Disease | denotes | hepatitis | http://purl.obolibrary.org/obo/MONDO_0002251 |
| T175 | 30813-30817 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T176 | 30946-30950 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T177 | 31163-31166 | Disease | denotes | EST | http://purl.obolibrary.org/obo/MONDO_0023726 |
| T178 | 31229-31238 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T179 | 31428-31432 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T180 | 31602-31606 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T181 | 31826-31830 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T182 | 32102-32112 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T183 | 32269-32273 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T184 | 32295-32300 | Disease | denotes | Ebola | http://purl.obolibrary.org/obo/MONDO_0005737 |
| T185 | 32411-32415 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T186 | 32553-32561 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T187 | 32686-32695 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T188 | 32932-32941 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T189 | 33423-33427 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T190 | 33626-33631 | Disease | denotes | Ebola | http://purl.obolibrary.org/obo/MONDO_0005737 |
| T191 | 33632-33647 | Disease | denotes | virus infection | http://purl.obolibrary.org/obo/MONDO_0005108 |
| T192 | 33638-33647 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T193 | 33857-33861 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T194 | 33866-33871 | Disease | denotes | Ebola | http://purl.obolibrary.org/obo/MONDO_0005737 |
| T195 | 33872-33888 | Disease | denotes | virus infections | http://purl.obolibrary.org/obo/MONDO_0005108 |
| T196 | 35282-35286 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T197 | 35400-35404 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T198 | 35510-35514 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T199 | 35521-35530 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T200 | 36196-36205 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T201 | 36381-36385 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T202 | 36914-36918 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T203 | 36933-36942 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T204 | 37581-37590 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T205 | 38250-38254 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T206 | 38367-38371 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T207 | 38438-38442 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T208 | 38485-38489 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T209 | 38495-38528 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T210 | 38709-38713 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T211 | 38956-38993 | Disease | denotes | porcine transmissible gastroenteritis | http://purl.obolibrary.org/obo/MONDO_0025420 |
| T212 | 38978-38993 | Disease | denotes | gastroenteritis | http://purl.obolibrary.org/obo/MONDO_0002269 |
| T213 | 39173-39177 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T214 | 39436-39440 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T215 | 39507-39511 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T216 | 40844-40848 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T217 | 40938-40942 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T218 | 40948-40981 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T219 | 42642-42646 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T220 | 42955-42965 | Disease | denotes | infectious | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T221 | 42966-42976 | Disease | denotes | bronchitis | http://purl.obolibrary.org/obo/MONDO_0003781 |
| T222 | 43028-43032 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T223 | 43087-43091 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T224 | 43229-43233 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T225 | 43268-43272 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T226 | 43349-43353 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T227 | 43395-43399 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T228 | 43455-43459 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T229 | 43505-43513 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T230 | 43608-43612 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T231 | 43681-43685 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T232 | 43917-43925 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T233 | 45796-45800 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T234 | 45923-45927 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T235 | 46113-46117 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T236 | 46211-46215 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T237 | 46221-46254 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T238 | 46492-46496 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T239 | 46623-46627 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T240 | 46949-46953 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T241 | 48155-48159 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T242 | 49775-49779 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T243 | 50041-50070 | Disease | denotes | feline infectious peritonitis | http://purl.obolibrary.org/obo/MONDO_0025491 |
| T244 | 50048-50058 | Disease | denotes | infectious | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T245 | 50059-50070 | Disease | denotes | peritonitis | http://purl.obolibrary.org/obo/MONDO_0004522 |
| T246 | 50728-50732 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T247 | 50966-50970 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T248 | 51282-51286 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T249 | 51652-51656 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T250 | 51985-51989 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T251 | 52056-52060 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T252 | 52066-52099 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T253 | 52596-52600 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T254 | 52709-52713 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T255 | 52747-52751 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T256 | 52757-52790 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T257 | 52869-52873 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T258 | 53173-53177 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T259 | 53489-53493 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T260 | 53509-53513 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T261 | 53647-53651 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T262 | 53760-53764 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T263 | 53832-53836 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T264 | 53904-53908 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T265 | 54309-54313 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T266 | 54352-54356 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T267 | 54362-54395 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T268 | 54973-54977 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T269 | 55224-55228 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T270 | 55283-55287 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T271 | 55396-55400 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T272 | 55453-55457 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T273 | 57167-57171 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T274 | 57205-57209 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T275 | 57215-57248 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T276 | 57968-57972 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T277 | 58071-58075 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T278 | 58918-58922 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T279 | 59857-59861 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T280 | 60337-60341 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T281 | 60375-60379 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T282 | 60385-60418 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T283 | 60856-60860 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T284 | 61104-61108 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T285 | 61240-61244 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T286 | 61749-61753 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T287 | 62331-62335 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T288 | 62354-62358 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T289 | 62364-62397 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T290 | 62481-62485 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T291 | 62580-62584 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T292 | 62705-62709 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T293 | 62889-62893 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T294 | 62966-62982 | Disease | denotes | immunodeficiency | http://purl.obolibrary.org/obo/MONDO_0021094 |
| T295 | 63011-63015 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T296 | 63021-63054 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T297 | 63213-63217 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T298 | 63486-63490 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T299 | 63535-63539 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T300 | 63545-63578 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T301 | 63854-63858 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T302 | 64154-64158 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T303 | 64594-64598 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T304 | 64643-64647 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T305 | 64653-64686 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T306 | 65207-65211 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T307 | 65426-65430 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T308 | 65475-65479 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T309 | 65485-65518 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T310 | 65647-65651 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T311 | 65767-65771 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T312 | 65896-65900 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T313 | 66463-66467 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T314 | 66518-66522 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T315 | 66610-66614 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T316 | 67080-67084 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T317 | 67371-67375 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T318 | 67765-67768 | Disease | denotes | HTS | http://purl.obolibrary.org/obo/MONDO_0011549 |
| T319 | 67840-67844 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T320 | 68509-68513 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T321 | 68558-68562 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T322 | 68568-68601 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T323 | 68683-68687 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T324 | 69022-69026 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T325 | 69135-69138 | Disease | denotes | HTS | http://purl.obolibrary.org/obo/MONDO_0011549 |
| T326 | 69259-69263 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T327 | 69466-69470 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T328 | 69515-69519 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T329 | 69525-69558 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T330 | 69618-69622 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T331 | 69837-69841 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T332 | 69998-70002 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T333 | 70161-70165 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T334 | 70273-70277 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T335 | 70358-70362 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T336 | 70368-70401 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T337 | 70876-70880 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T338 | 71012-71016 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T339 | 71061-71065 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T340 | 71148-71152 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T341 | 71158-71191 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T342 | 71837-71841 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T343 | 72338-72342 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T344 | 72383-72387 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T345 | 72393-72426 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T346 | 72506-72510 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T347 | 73164-73168 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T348 | 73260-73264 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T349 | 73401-73405 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T350 | 73717-73721 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T351 | 73774-73778 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T352 | 73784-73817 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T353 | 74015-74019 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T354 | 74115-74118 | Disease | denotes | HTS | http://purl.obolibrary.org/obo/MONDO_0011549 |
| T355 | 74214-74218 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T356 | 74352-74356 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T357 | 74544-74548 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T358 | 74628-74632 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T359 | 74693-74697 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T360 | 74782-74785 | Disease | denotes | HTS | http://purl.obolibrary.org/obo/MONDO_0011549 |
| T361 | 75505-75509 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T362 | 75876-75886 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T363 | 76779-76783 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T364 | 76907-76910 | Disease | denotes | HTS | http://purl.obolibrary.org/obo/MONDO_0011549 |
| T365 | 77002-77006 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T366 | 77725-77729 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T367 | 77813-77817 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T368 | 77823-77856 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T369 | 78354-78358 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T370 | 79315-79319 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T371 | 79434-79437 | Disease | denotes | HTS | http://purl.obolibrary.org/obo/MONDO_0011549 |
| T372 | 79516-79520 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T373 | 79707-79711 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T374 | 79771-79775 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T375 | 80000-80004 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T376 | 80010-80043 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T377 | 80128-80132 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T378 | 80361-80365 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T379 | 80442-80446 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T380 | 80564-80568 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T381 | 80644-80648 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T382 | 80858-80862 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T383 | 81030-81034 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T384 | 81139-81143 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T385 | 81269-81273 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T386 | 81969-81973 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T387 | 82715-82723 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T388 | 82873-82877 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T389 | 82993-82997 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T390 | 83003-83036 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T391 | 83192-83203 | Disease | denotes | hepatitis C | http://purl.obolibrary.org/obo/MONDO_0005231 |
| T392 | 83192-83201 | Disease | denotes | hepatitis | http://purl.obolibrary.org/obo/MONDO_0002251 |
| T393 | 83581-83585 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T394 | 83675-83679 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T395 | 84329-84333 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T396 | 84468-84471 | Disease | denotes | HAE | http://purl.obolibrary.org/obo/MONDO_0019623 |
| T397 | 84544-84548 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T398 | 84655-84659 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T399 | 84712-84716 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T400 | 84837-84846 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T401 | 85190-85195 | Disease | denotes | Ebola | http://purl.obolibrary.org/obo/MONDO_0005737 |
| T402 | 85208-85224 | Disease | denotes | virus infections | http://purl.obolibrary.org/obo/MONDO_0005108 |
| T403 | 85255-85259 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T404 | 85356-85360 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T405 | 85740-85756 | Disease | denotes | viral infections | http://purl.obolibrary.org/obo/MONDO_0005108 |
| T406 | 85788-85792 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T407 | 85902-85910 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T408 | 85998-86007 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T409 | 86511-86519 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T410 | 86702-86706 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T411 | 87014-87022 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T412 | 87302-87310 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T413 | 87747-87751 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T414 | 88098-88102 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T415 | 88274-88278 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T416 | 88300-88304 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T417 | 88530-88534 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T418 | 88754-88758 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T419 | 88839-88843 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T420 | 88983-88987 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T421 | 89120-89130 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T422 | 89207-89211 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T423 | 89225-89229 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T424 | 89235-89268 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T425 | 89348-89352 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T426 | 89776-89780 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T427 | 89882-89886 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T428 | 90036-90040 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T429 | 90188-90192 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T430 | 90342-90346 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T431 | 90589-90593 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T432 | 90633-90637 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T433 | 92237-92245 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T434 | 92660-92664 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T435 | 93273-93277 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T436 | 93430-93434 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T437 | 93579-93583 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T438 | 93641-93656 | Disease | denotes | viral infection | http://purl.obolibrary.org/obo/MONDO_0005108 |
| T439 | 93647-93656 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T440 | 93823-93827 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T441 | 93952-93956 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T442 | 94004-94008 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T443 | 94506-94510 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T444 | 94517-94526 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T445 | 94855-94859 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T446 | 95163-95169 | Disease | denotes | asthma | http://purl.obolibrary.org/obo/MONDO_0004979 |
| T447 | 95174-95191 | Disease | denotes | allergic rhinitis | http://purl.obolibrary.org/obo/MONDO_0011786 |
| T448 | 95174-95182 | Disease | denotes | allergic | http://purl.obolibrary.org/obo/MONDO_0004980 |
| T449 | 95183-95191 | Disease | denotes | rhinitis | http://purl.obolibrary.org/obo/MONDO_0003014 |
| T450 | 95293-95297 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T451 | 95338-95346 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T452 | 95699-95707 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T453 | 95815-95819 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T454 | 96030-96038 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T455 | 96111-96115 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T456 | 96177-96189 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T457 | 96221-96229 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T458 | 96295-96303 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T459 | 96364-96377 | Disease | denotes | peptic ulcers | http://purl.obolibrary.org/obo/MONDO_0004247 |
| T460 | 96371-96377 | Disease | denotes | ulcers | http://purl.obolibrary.org/obo/MONDO_0043839 |
| T461 | 96382-96413 | Disease | denotes | gastroesophageal reflux disease | http://purl.obolibrary.org/obo/MONDO_0007186 |
| T462 | 96505-96513 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T463 | 96560-96568 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T464 | 96686-96696 | Disease | denotes | blood clot | http://purl.obolibrary.org/obo/MONDO_0000831 |
| T465 | 96749-96757 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T466 | 96854-96874 | Disease | denotes | erectile dysfunction | http://purl.obolibrary.org/obo/MONDO_0005362 |
| T467 | 96879-96910 | Disease | denotes | pulmonary arterial hypertension | http://purl.obolibrary.org/obo/MONDO_0015924|http://purl.obolibrary.org/obo/MONDO_0024533 |
| T469 | 96898-96910 | Disease | denotes | hypertension | http://purl.obolibrary.org/obo/MONDO_0005044 |
| T470 | 96981-96989 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T471 | 97209-97213 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T472 | 97329-97333 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T473 | 97340-97349 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T474 | 97445-97449 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T475 | 97727-97735 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T476 | 97764-97768 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T477 | 97977-97981 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T478 | 98228-98232 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T479 | 98291-98295 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T480 | 98300-98308 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T481 | 98343-98347 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T482 | 98664-98668 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T483 | 98837-98841 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T484 | 98846-98856 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T485 | 98898-98902 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T486 | 98908-98941 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T487 | 98990-98994 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T488 | 99078-99086 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T489 | 99246-99250 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T490 | 99321-99334 | Disease | denotes | schizophrenia | http://purl.obolibrary.org/obo/MONDO_0005090 |
| T491 | 99520-99524 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T492 | 99641-99649 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T493 | 99704-99712 | Disease | denotes | diarrhea | http://purl.obolibrary.org/obo/MONDO_0001673 |
| T494 | 99748-99752 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T495 | 99864-99868 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T496 | 100425-100444 | Disease | denotes | malignant neoplasms | http://purl.obolibrary.org/obo/MONDO_0004992|http://purl.obolibrary.org/obo/MONDO_0006517 |
| T498 | 100534-100538 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T499 | 100736-100740 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T500 | 100979-100989 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T501 | 101150-101158 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T502 | 101534-101542 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T503 | 103683-103691 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T504 | 104125-104129 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T505 | 104140-104144 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T506 | 104180-104189 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T507 | 104422-104426 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T508 | 104907-104911 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T509 | 105056-105060 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T510 | 105338-105342 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T511 | 105423-105431 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T512 | 105931-105935 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T513 | 106707-106711 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T514 | 107132-107140 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T515 | 107598-107606 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T516 | 107937-107941 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T517 | 109157-109159 | Disease | denotes | he | http://purl.obolibrary.org/obo/MONDO_0017319 |
| T518 | 109640-109642 | Disease | denotes | he | http://purl.obolibrary.org/obo/MONDO_0017319 |
| T519 | 109694-109698 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T520 | 109946-109948 | Disease | denotes | he | http://purl.obolibrary.org/obo/MONDO_0017319 |
| T521 | 110035-110037 | Disease | denotes | he | http://purl.obolibrary.org/obo/MONDO_0017319 |
| T522 | 110441-110443 | Disease | denotes | he | http://purl.obolibrary.org/obo/MONDO_0017319 |
| T523 | 110619-110621 | Disease | denotes | he | http://purl.obolibrary.org/obo/MONDO_0017319 |
| T524 | 110861-110874 | Disease | denotes | heart failure | http://purl.obolibrary.org/obo/MONDO_0005252 |
| T525 | 110876-110888 | Disease | denotes | hypertension | http://purl.obolibrary.org/obo/MONDO_0005044 |
| T526 | 110893-110899 | Disease | denotes | cancer | http://purl.obolibrary.org/obo/MONDO_0004992 |
| T527 | 111165-111167 | Disease | denotes | he | http://purl.obolibrary.org/obo/MONDO_0017319 |
| T528 | 111304-111306 | Disease | denotes | he | http://purl.obolibrary.org/obo/MONDO_0017319 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 99906-99907 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T2 | 100029-100030 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T3 | 100177-100185 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T4 | 100304-100312 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T5 | 100351-100352 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T6 | 100449-100452 | http://purl.obolibrary.org/obo/CLO_0009132 | denotes | Src |
| T7 | 100682-100692 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
| T8 | 100756-100759 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T9 | 100814-100815 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T10 | 100852-100864 | http://purl.obolibrary.org/obo/OBI_0000245 | denotes | Organization |
| T11 | 101023-101026 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T12 | 101312-101313 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T13 | 101866-101868 | http://purl.obolibrary.org/obo/CLO_0053755 | denotes | ES |
| T14 | 102684-102686 | http://purl.obolibrary.org/obo/CLO_0053755 | denotes | ES |
| T15 | 102855-102857 | http://purl.obolibrary.org/obo/CLO_0053755 | denotes | ES |
| T16 | 104046-104054 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T17 | 104071-104076 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T18 | 104116-104123 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T19 | 104157-104158 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T20 | 104215-104220 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T21 | 104657-104662 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T22 | 104663-104667 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T23 | 104668-104676 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T24 | 104691-104692 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T25 | 104731-104739 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptides |
| T26 | 104856-104864 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptides |
| T27 | 104912-104920 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T28 | 105230-105231 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T29 | 105264-105271 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T30 | 105283-105286 | http://purl.obolibrary.org/obo/NCBITaxon_9397 | denotes | bat |
| T31 | 105315-105316 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T32 | 105449-105450 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T33 | 106080-106085 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T34 | 106167-106172 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T35 | 106294-106295 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T36 | 106383-106386 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T37 | 106536-106537 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T38 | 106781-106786 | http://purl.obolibrary.org/obo/UBERON_0001456 | denotes | faced |
| T39 | 106830-106831 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T40 | 106932-106933 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T41 | 106959-106960 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T42 | 106991-106992 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T43 | 107044-107050 | http://purl.obolibrary.org/obo/UBERON_0007688 | denotes | fields |
| T44 | 107072-107079 | http://purl.obolibrary.org/obo/OBI_0100026 | denotes | organic |
| T45 | 107072-107079 | http://purl.obolibrary.org/obo/UBERON_0000468 | denotes | organic |
| T46 | 107101-107102 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T47 | 107772-107775 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T48 | 107990-107995 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | Human |
| T49 | 108229-108235 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
| T50 | 108427-108428 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T51 | 108493-108498 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T52 | 108672-108674 | http://purl.obolibrary.org/obo/CLO_0007653 | denotes | ME |
| T53 | 108941-108950 | http://purl.obolibrary.org/obo/OBI_0000245 | denotes | organized |
| T54 | 109164-109165 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T55 | 109514-109515 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T56 | 109722-109749 | http://purl.obolibrary.org/obo/PR_000030035 | denotes | G‐protein‐coupled receptors |
| T57 | 109769-109770 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T58 | 109968-109969 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T59 | 110109-110136 | http://purl.obolibrary.org/obo/PR_000030035 | denotes | G protein‐coupled receptors |
| T60 | 110177-110185 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | actively |
| T61 | 110370-110371 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T62 | 110765-110773 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | actively |
| T63 | 110861-110866 | http://purl.obolibrary.org/obo/UBERON_0000948 | denotes | heart |
| T64 | 110861-110866 | http://purl.obolibrary.org/obo/UBERON_0007100 | denotes | heart |
| T65 | 110861-110866 | http://purl.obolibrary.org/obo/UBERON_0015228 | denotes | heart |
| T66 | 110861-110866 | http://www.ebi.ac.uk/efo/EFO_0000815 | denotes | heart |
| T67 | 111105-111106 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T68 | 111247-111248 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T69 | 111451-111459 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | actively |
| T97437 | 24-29 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T17442 | 45-46 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T94379 | 148-154 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
| T52125 | 159-166 | http://purl.obolibrary.org/obo/NCBITaxon_33208 | denotes | animals |
| T67426 | 171-177 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
| T99451 | 207-213 | http://purl.obolibrary.org/obo/UBERON_0002113 | denotes | kidney |
| T89987 | 207-213 | http://www.ebi.ac.uk/efo/EFO_0000927 | denotes | kidney |
| T29008 | 207-213 | http://www.ebi.ac.uk/efo/EFO_0000929 | denotes | kidney |
| T86367 | 215-220 | http://purl.obolibrary.org/obo/UBERON_0000948 | denotes | heart |
| T59948 | 215-220 | http://purl.obolibrary.org/obo/UBERON_0007100 | denotes | heart |
| T63891 | 215-220 | http://purl.obolibrary.org/obo/UBERON_0015228 | denotes | heart |
| T79729 | 215-220 | http://www.ebi.ac.uk/efo/EFO_0000815 | denotes | heart |
| T45711 | 222-227 | http://purl.obolibrary.org/obo/UBERON_0000955 | denotes | brain |
| T97993 | 222-227 | http://www.ebi.ac.uk/efo/EFO_0000302 | denotes | brain |
| T35050 | 233-243 | http://purl.obolibrary.org/obo/UBERON_0000160 | denotes | intestinal |
| T97808 | 233-243 | http://www.ebi.ac.uk/efo/EFO_0000834 | denotes | intestinal |
| T95899 | 393-399 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
| T99550 | 528-535 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T70264 | 585-593 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human to |
| T19920 | 594-599 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T66400 | 782-787 | http://purl.obolibrary.org/obo/CLO_0009985 | denotes | focus |
| T24772 | 1474-1476 | http://purl.obolibrary.org/obo/CLO_0007874 | denotes | MS |
| T43196 | 1644-1651 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | Viruses |
| T85981 | 1725-1730 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
| T87791 | 1741-1746 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T37774 | 2062-2067 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T11604 | 2150-2156 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
| T5178 | 2161-2168 | http://purl.obolibrary.org/obo/NCBITaxon_33208 | denotes | animals |
| T31670 | 2173-2179 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
| T3715 | 2227-2237 | http://purl.obolibrary.org/obo/UBERON_0000160 | denotes | intestinal |
| T79590 | 2227-2237 | http://www.ebi.ac.uk/efo/EFO_0000834 | denotes | intestinal |
| T50277 | 2354-2361 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | Viruses |
| T43872 | 2629-2634 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T29355 | 2693-2698 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T93748 | 2901-2908 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T48181 | 3122-3128 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
| T69382 | 3422-3429 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | Viruses |
| T10981 | 3442-3447 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T60379 | 3642-3649 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T46824 | 3654-3663 | http://www.ebi.ac.uk/efo/EFO_0000876 | denotes | extremely |
| T659 | 3718-3724 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
| T27968 | 3880-3881 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T17456 | 3954-3956 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 35 |
| T90786 | 4025-4028 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T90780 | 4099-4100 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T90040 | 4214-4217 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T35962 | 4326-4329 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T77830 | 4338-4339 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T42923 | 4448-4453 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T38003 | 4559-4564 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T13704 | 4626-4631 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T8510 | 4665-4670 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | Human |
| T17454 | 4784-4789 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T71188 | 4800-4806 | http://purl.obolibrary.org/obo/NCBITaxon_33208 | denotes | animal |
| T92490 | 4913-4917 | http://purl.obolibrary.org/obo/NCBITaxon_9397 | denotes | bats |
| T57185 | 4974-4976 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T84928 | 5039-5046 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T55651 | 5208-5213 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T3796 | 5322-5327 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T12827 | 5349-5354 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T39682 | 5445-5453 | http://purl.obolibrary.org/obo/OBI_0100026 | denotes | organism |
| T83802 | 5445-5453 | http://purl.obolibrary.org/obo/UBERON_0000468 | denotes | organism |
| T24191 | 5542-5546 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T46527 | 5552-5557 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T45085 | 5616-5624 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T69167 | 5781-5782 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T47624 | 5869-5870 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T84513 | 5900-5904 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T12765 | 5915-5919 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T70 | 6024-6025 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T71 | 6091-6096 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T72 | 6302-6307 | http://purl.obolibrary.org/obo/CLO_0007919 | denotes | N; 18 |
| T73 | 6907-6912 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | Human |
| T74 | 6938-6942 | http://purl.obolibrary.org/obo/NCBITaxon_9397 | denotes | Bats |
| T75 | 6979-6983 | http://purl.obolibrary.org/obo/NCBITaxon_9397 | denotes | bats |
| T76 | 7161-7165 | http://purl.obolibrary.org/obo/NCBITaxon_9397 | denotes | Bats |
| T77 | 7167-7173 | http://purl.obolibrary.org/obo/NCBITaxon_9837 | denotes | camels |
| T78 | 7198-7202 | http://purl.obolibrary.org/obo/NCBITaxon_9397 | denotes | Bats |
| T79 | 7269-7273 | http://purl.obolibrary.org/obo/NCBITaxon_9397 | denotes | bats |
| T80 | 7760-7762 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T81 | 7767-7769 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T82 | 7767-7769 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T83 | 7805-7807 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T84 | 7840-7842 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T85 | 7840-7842 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T86 | 7874-7880 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell's |
| T87 | 7973-7981 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T88 | 7996-8002 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell's |
| T89 | 8003-8011 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T90 | 8049-8054 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T91 | 8091-8097 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell's |
| T92 | 8113-8120 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus's |
| T93 | 8647-8649 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T94 | 8888-8896 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T95 | 8948-8950 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T96 | 8999-9000 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T97 | 9360-9365 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T98 | 9419-9427 | http://purl.obolibrary.org/obo/OBI_0100026 | denotes | organism |
| T99 | 9419-9427 | http://purl.obolibrary.org/obo/UBERON_0000468 | denotes | organism |
| T100 | 9441-9446 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T101 | 9493-9494 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T102 | 9610-9623 | http://purl.obolibrary.org/obo/PR_000001091 | denotes | interleukin 1 |
| T103 | 9638-9642 | http://purl.obolibrary.org/obo/CLO_0053704 | denotes | IL‐8 |
| T104 | 9719-9724 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T105 | 9725-9733 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activate |
| T106 | 9920-9921 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T107 | 9940-9953 | http://purl.obolibrary.org/obo/PR_000029067 | denotes | human protein |
| T108 | 10066-10069 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T109 | 10543-10550 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T110 | 10596-10597 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T111 | 10682-10687 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | VIRUS |
| T112 | 10801-10806 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T113 | 10908-10911 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T114 | 11007-11010 | http://purl.obolibrary.org/obo/NCBITaxon_9397 | denotes | bat |
| T115 | 11196-11197 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T116 | 11375-11377 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
| T117 | 11731-11732 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T118 | 11810-11812 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T119 | 11826-11827 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T120 | 11864-11866 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T121 | 11864-11866 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T122 | 12198-12203 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T123 | 12255-12256 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T124 | 12370-12371 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T125 | 12396-12397 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T126 | 12398-12401 | http://purl.obolibrary.org/obo/NCBITaxon_9397 | denotes | bat |
| T127 | 12564-12569 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T128 | 12762-12764 | http://purl.obolibrary.org/obo/CLO_0001627 | denotes | aa |
| T129 | 12787-12789 | http://purl.obolibrary.org/obo/CLO_0001627 | denotes | aa |
| T130 | 12817-12820 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T131 | 12834-12836 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T132 | 12841-12843 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T133 | 12841-12843 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T134 | 12849-12851 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T135 | 12877-12880 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T136 | 12881-12882 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T137 | 13014-13019 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T138 | 13025-13029 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T139 | 13080-13081 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T140 | 13646-13648 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
| T141 | 13936-13937 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T142 | 14101-14109 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T143 | 14117-14123 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tested |
| T144 | 14220-14237 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity for cell |
| T145 | 14285-14286 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T146 | 14392-14393 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T147 | 14510-14516 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T148 | 14688-14690 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 35 |
| T149 | 14701-14702 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T150 | 14713-14721 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptides |
| T151 | 14884-14886 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T152 | 14959-14967 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptides |
| T153 | 14968-14970 | http://purl.obolibrary.org/obo/CLO_0008337 | denotes | P4 |
| T154 | 15035-15043 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T155 | 15078-15086 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T156 | 15160-15167 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T157 | 15168-15170 | http://purl.obolibrary.org/obo/CLO_0008337 | denotes | P4 |
| T158 | 15181-15183 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T159 | 15209-15216 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T160 | 15227-15230 | http://purl.obolibrary.org/obo/CLO_0001310 | denotes | 351 |
| T161 | 15244-15245 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T162 | 15333-15335 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
| T163 | 15367-15368 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T164 | 15489-15494 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T165 | 15512-15513 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T166 | 15543-15550 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T167 | 15768-15773 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T168 | 15812-15814 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 35 |
| T169 | 15830-15831 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T170 | 15897-15901 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T171 | 15974-15980 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
| T172 | 16027-16037 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
| T173 | 16051-16056 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T174 | 16070-16075 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
| T175 | 16083-16085 | http://purl.obolibrary.org/obo/CLO_0053794 | denotes | 41 |
| T176 | 16102-16104 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
| T177 | 16187-16188 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T178 | 16246-16252 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T179 | 16310-16315 | http://purl.obolibrary.org/obo/CLO_0009989 | denotes | Huh‐7 |
| T180 | 16316-16321 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T181 | 16444-16457 | http://purl.obolibrary.org/obo/CLO_0051719 | denotes | Vero E6 cells |
| T182 | 16480-16481 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T183 | 16504-16505 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T184 | 16557-16558 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T185 | 16567-16575 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T186 | 16630-16632 | http://purl.obolibrary.org/obo/CLO_0003622 | denotes | HB |
| T187 | 16730-16737 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T188 | 16777-16780 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T189 | 16837-16845 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptides |
| T190 | 16898-16899 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T191 | 16937-16944 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T192 | 16988-16993 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T193 | 17002-17007 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T194 | 17015-17020 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T195 | 17073-17078 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T196 | 17104-17109 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T197 | 17137-17142 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T198 | 17156-17158 | http://purl.obolibrary.org/obo/CLO_0053799 | denotes | 45 |
| T199 | 17226-17227 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T200 | 17440-17448 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptides |
| T201 | 17746-17747 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T202 | 17906-17907 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T203 | 18011-18013 | http://purl.obolibrary.org/obo/CLO_0001382 | denotes | 48 |
| T204 | 18204-18206 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T205 | 18204-18206 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T206 | 18242-18255 | http://purl.obolibrary.org/obo/CLO_0051719 | denotes | Vero E6 cells |
| T207 | 18548-18551 | http://purl.obolibrary.org/obo/CLO_0001203 | denotes | 232 |
| T208 | 18747-18755 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T209 | 18810-18811 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T210 | 18863-18865 | http://purl.obolibrary.org/obo/CLO_0006987 | denotes | J1 |
| T211 | 18883-18884 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T212 | 19010-19011 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T213 | 19086-19091 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T214 | 19256-19260 | http://purl.obolibrary.org/obo/CLO_0009524 | denotes | Vero |
| T215 | 19256-19260 | http://purl.obolibrary.org/obo/CLO_0050515 | denotes | Vero |
| T216 | 19261-19266 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T217 | 19295-19297 | http://purl.obolibrary.org/obo/CLO_0001407 | denotes | 52 |
| T218 | 19505-19512 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T219 | 19588-19589 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T220 | 19607-19612 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T221 | 19620-19623 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T222 | 19656-19667 | http://purl.obolibrary.org/obo/UBERON_0001986 | denotes | endothelium |
| T223 | 19680-19684 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T224 | 19680-19684 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T225 | 19718-19728 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
| T226 | 19729-19734 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T227 | 19758-19768 | http://purl.obolibrary.org/obo/CLO_0009900 | denotes | 76% of its |
| T228 | 19812-19813 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T229 | 19956-19958 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
| T230 | 20033-20037 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T231 | 20033-20037 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T232 | 20044-20045 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T233 | 20082-20090 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T234 | 20180-20185 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T235 | 20180-20185 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T236 | 20238-20246 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptides |
| T237 | 20570-20574 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T238 | 20570-20574 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T239 | 20864-20865 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T240 | 20910-20918 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptides |
| T241 | 20923-20924 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T242 | 21114-21115 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T243 | 21231-21249 | http://purl.obolibrary.org/obo/CHEBI_33708 | denotes | amino acid residue |
| T244 | 21231-21249 | http://purl.obolibrary.org/obo/PR_000036907 | denotes | amino acid residue |
| T245 | 21336-21337 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T246 | 21374-21377 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T247 | 21394-21395 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T248 | 21486-21487 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T249 | 21704-21705 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T250 | 21988-21989 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T251 | 22138-22139 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T252 | 22189-22198 | http://purl.obolibrary.org/obo/GO_0005764 | denotes | lysosomal |
| T253 | 22265-22274 | http://purl.obolibrary.org/obo/GO_0005764 | denotes | lysosomes |
| T254 | 22280-22285 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T255 | 22347-22351 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T256 | 22587-22593 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T257 | 22738-22746 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T258 | 22805-22809 | http://purl.obolibrary.org/obo/CLO_0009524 | denotes | Vero |
| T259 | 22805-22809 | http://purl.obolibrary.org/obo/CLO_0050515 | denotes | Vero |
| T260 | 22810-22815 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T261 | 22860-22868 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T262 | 22884-22894 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
| T263 | 22895-22912 | http://purl.obolibrary.org/obo/CL_0000003 | denotes | cells and in vivo |
| T264 | 23220-23223 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T265 | 23348-23350 | http://purl.obolibrary.org/obo/CLO_0054055 | denotes | 71 |
| T266 | 23396-23401 | http://purl.obolibrary.org/obo/UBERON_0000948 | denotes | heart |
| T267 | 23396-23401 | http://purl.obolibrary.org/obo/UBERON_0007100 | denotes | heart |
| T268 | 23396-23401 | http://purl.obolibrary.org/obo/UBERON_0015228 | denotes | heart |
| T269 | 23396-23401 | http://www.ebi.ac.uk/efo/EFO_0000815 | denotes | heart |
| T270 | 23634-23638 | http://purl.obolibrary.org/obo/NCBITaxon_117565 | denotes | fish |
| T271 | 23993-23999 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T272 | 24032-24037 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T273 | 24191-24192 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T274 | 24300-24301 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T275 | 24513-24520 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | testing |
| T276 | 24565-24570 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tests |
| T277 | 24688-24691 | http://www.ebi.ac.uk/efo/EFO_0001410 | denotes | arm |
| T278 | 24867-24869 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T279 | 25113-25114 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T280 | 25276-25277 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T281 | 25363-25364 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T282 | 26013-26014 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T283 | 26052-26053 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T284 | 26183-26184 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T285 | 26415-26416 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T286 | 26469-26473 | http://purl.obolibrary.org/obo/CLO_0001757 | denotes | at 1 |
| T287 | 26511-26513 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T288 | 26666-26674 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T289 | 26710-26716 | http://purl.obolibrary.org/obo/CLO_0008462 | denotes | pM. 85 |
| T290 | 26797-26802 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T291 | 26842-26843 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T292 | 26914-26920 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T293 | 26965-26972 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T294 | 27066-27067 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T295 | 27068-27073 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T296 | 27079-27083 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T297 | 27162-27167 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T298 | 27176-27177 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T299 | 27243-27244 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T300 | 27334-27339 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T301 | 27345-27349 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T302 | 27400-27401 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T303 | 27889-27894 | http://purl.obolibrary.org/obo/UBERON_0000948 | denotes | heart |
| T304 | 27889-27894 | http://purl.obolibrary.org/obo/UBERON_0007100 | denotes | heart |
| T305 | 27889-27894 | http://purl.obolibrary.org/obo/UBERON_0015228 | denotes | heart |
| T306 | 27889-27894 | http://www.ebi.ac.uk/efo/EFO_0000815 | denotes | heart |
| T307 | 28091-28096 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
| T308 | 28168-28173 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T309 | 28168-28173 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T310 | 28222-28223 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T311 | 28311-28312 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T312 | 28313-28318 | http://purl.obolibrary.org/obo/UBERON_0000982 | denotes | joint |
| T313 | 28313-28318 | http://purl.obolibrary.org/obo/UBERON_0004905 | denotes | joint |
| T314 | 28403-28404 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T315 | 28546-28548 | http://purl.obolibrary.org/obo/CLO_0001527 | denotes | 94 |
| T316 | 28764-28765 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T317 | 28795-28799 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T318 | 28795-28799 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T319 | 28873-28878 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T320 | 29241-29251 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
| T321 | 29309-29318 | http://purl.obolibrary.org/obo/GO_0005764 | denotes | lysosomes |
| T322 | 29338-29347 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activates |
| T323 | 29473-29477 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T324 | 29518-29523 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T325 | 29529-29537 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | Membrane |
| T326 | 29698-29704 | http://purl.obolibrary.org/obo/UBERON_0001005 | denotes | airway |
| T327 | 29753-29755 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T328 | 29756-29758 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T329 | 29756-29758 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T330 | 29776-29784 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activate |
| T331 | 29803-29811 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T332 | 29951-29952 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T333 | 30043-30055 | http://purl.obolibrary.org/obo/CLO_0051719 | denotes | VeroE6 cells |
| T334 | 30067-30068 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T335 | 30090-30099 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activates |
| T336 | 30146-30154 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T337 | 30169-30172 | http://purl.obolibrary.org/obo/CLO_0054060 | denotes | 102 |
| T338 | 30407-30408 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T339 | 30483-30488 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T340 | 30511-30516 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T341 | 30540-30545 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T342 | 30558-30563 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
| T343 | 30574-30579 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T344 | 30791-30793 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T345 | 30811-30812 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T346 | 30852-30860 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T347 | 30883-30884 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T348 | 30976-30980 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T349 | 31048-31050 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 35 |
| T350 | 31146-31147 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T351 | 31168-31169 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T352 | 31195-31197 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T353 | 31246-31254 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T354 | 31270-31277 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T355 | 31361-31362 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T356 | 31380-31383 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T357 | 31515-31516 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T358 | 31537-31539 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T359 | 31551-31552 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T360 | 31625-31630 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T361 | 31634-31635 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T362 | 31676-31678 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T363 | 31682-31683 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T364 | 31755-31756 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T365 | 31927-31933 | http://purl.obolibrary.org/obo/NCBITaxon_33208 | denotes | animal |
| T366 | 32002-32010 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T367 | 32060-32061 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T368 | 32132-32140 | http://purl.obolibrary.org/obo/NCBITaxon_2 | denotes | bacteria |
| T369 | 32301-32306 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T370 | 32366-32369 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T371 | 32510-32511 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T372 | 32615-32620 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | Human |
| T373 | 32636-32637 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T374 | 32671-32672 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T375 | 32710-32720 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
| T376 | 32743-32744 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T377 | 32857-32862 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T378 | 32863-32867 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T379 | 32891-32892 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T380 | 32943-32946 | http://purl.obolibrary.org/obo/CLO_0053001 | denotes | 114 |
| T381 | 33197-33205 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T382 | 33311-33319 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T383 | 33380-33382 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T384 | 33435-33436 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T385 | 33539-33541 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T386 | 33597-33599 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T387 | 33632-33637 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T388 | 33666-33671 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T389 | 33672-33688 | http://www.ebi.ac.uk/efo/EFO_0000927 | denotes | embryonic kidney |
| T390 | 33689-33693 | http://purl.obolibrary.org/obo/CLO_0050894 | denotes | 293T |
| T391 | 33689-33693 | http://purl.obolibrary.org/obo/CLO_0051650 | denotes | 293T |
| T392 | 33689-33693 | http://purl.obolibrary.org/obo/CLO_0052052 | denotes | 293T |
| T393 | 33694-33699 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T394 | 33752-33757 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T395 | 33758-33764 | http://www.ebi.ac.uk/efo/EFO_0000265 | denotes | aortic |
| T396 | 33765-33782 | http://purl.obolibrary.org/obo/CL_0000115 | denotes | endothelial cells |
| T397 | 33814-33815 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T398 | 33872-33877 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T399 | 33890-33893 | http://purl.obolibrary.org/obo/CLO_0001046 | denotes | 116 |
| T400 | 33928-33934 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a cell |
| T401 | 34079-34080 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T402 | 34107-34111 | http://purl.obolibrary.org/obo/CLO_0050894 | denotes | 293T |
| T403 | 34107-34111 | http://purl.obolibrary.org/obo/CLO_0051650 | denotes | 293T |
| T404 | 34107-34111 | http://purl.obolibrary.org/obo/CLO_0052052 | denotes | 293T |
| T405 | 34112-34117 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T406 | 34206-34208 | http://purl.obolibrary.org/obo/CLO_0001382 | denotes | 48 |
| T407 | 34316-34319 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T408 | 34354-34360 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T409 | 34417-34421 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T410 | 34587-34593 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T411 | 34812-34825 | http://purl.obolibrary.org/obo/CLO_0051719 | denotes | Vero E6 cells |
| T412 | 34930-34932 | http://purl.obolibrary.org/obo/CLO_0001382 | denotes | 48 |
| T413 | 34960-34961 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T414 | 35004-35009 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T415 | 35010-35014 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T416 | 35015-35023 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T417 | 35113-35114 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T418 | 35304-35309 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T419 | 35316-35317 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T420 | 35485-35487 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
| T421 | 35547-35550 | http://purl.obolibrary.org/obo/CLO_0001053 | denotes | 121 |
| T422 | 35568-35569 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T423 | 35712-35717 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T424 | 35950-35952 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T425 | 36344-36345 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T426 | 36461-36464 | http://purl.obolibrary.org/obo/CLO_0054060 | denotes | 102 |
| T427 | 36621-36627 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T428 | 36638-36639 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T429 | 36782-36789 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T430 | 36822-36823 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T431 | 36977-36984 | http://purl.obolibrary.org/obo/CLO_0009985 | denotes | focused |
| T432 | 37095-37100 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T433 | 37102-37110 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | Peptides |
| T434 | 37309-37317 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T435 | 37359-37367 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T436 | 37424-37432 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T437 | 37567-37568 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T438 | 37595-37596 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T439 | 37688-37695 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | testing |
| T440 | 37887-37888 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T441 | 37923-37924 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T442 | 38029-38030 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T443 | 38069-38076 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | Peptide |
| T444 | 38114-38115 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T445 | 38164-38172 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptides |
| T446 | 38219-38226 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T447 | 38333-38351 | http://purl.obolibrary.org/obo/CHEBI_33708 | denotes | amino acid residue |
| T448 | 38333-38351 | http://purl.obolibrary.org/obo/PR_000036907 | denotes | amino acid residue |
| T449 | 38364-38365 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T450 | 38411-38412 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T451 | 38640-38641 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T452 | 38741-38742 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T453 | 38743-38751 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptidic |
| T454 | 38766-38769 | http://purl.obolibrary.org/obo/CLO_0037067 | denotes | Val |
| T455 | 38929-38930 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T456 | 39021-39022 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T457 | 39054-39056 | http://purl.obolibrary.org/obo/CLO_0008285 | denotes | P1 |
| T458 | 39096-39098 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T459 | 39120-39122 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T460 | 39162-39164 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T461 | 39162-39164 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T462 | 39230-39231 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T463 | 39260-39265 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T464 | 39492-39498 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T465 | 39630-39631 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T466 | 39677-39685 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T467 | 39725-39727 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T468 | 39743-39745 | http://purl.obolibrary.org/obo/CLO_0008285 | denotes | P1 |
| T469 | 39769-39770 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T470 | 39800-39808 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T471 | 39843-39845 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T472 | 39879-39880 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T473 | 39936-39937 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T474 | 39987-39995 | http://purl.obolibrary.org/obo/CLO_0009985 | denotes | focusing |
| T475 | 40028-40030 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T476 | 40090-40092 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T477 | 40234-40238 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T478 | 40252-40254 | http://purl.obolibrary.org/obo/CLO_0053799 | denotes | 45 |
| T479 | 40274-40277 | http://purl.obolibrary.org/obo/CLO_0054061 | denotes | 132 |
| T480 | 40377-40383 | http://purl.obolibrary.org/obo/CLO_0001751 | denotes | and 33 |
| T481 | 40500-40502 | http://purl.obolibrary.org/obo/CLO_0008337 | denotes | P4 |
| T482 | 40591-40593 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
| T483 | 40628-40636 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T484 | 40736-40738 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
| T485 | 40770-40772 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 35 |
| T486 | 40790-40798 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T487 | 40825-40827 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T488 | 40840-40842 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T489 | 40900-40901 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T490 | 41039-41040 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T491 | 41051-41058 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T492 | 41075-41076 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T493 | 41178-41179 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T494 | 41266-41268 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
| T495 | 41299-41301 | http://purl.obolibrary.org/obo/CLO_0008285 | denotes | P1 |
| T496 | 41332-41333 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T497 | 41363-41365 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T498 | 41473-41475 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
| T499 | 41478-41480 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T500 | 41496-41497 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T501 | 41528-41536 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T502 | 41558-41560 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T503 | 41607-41608 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T504 | 41660-41661 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T505 | 41732-41734 | http://purl.obolibrary.org/obo/CLO_0008337 | denotes | P4 |
| T506 | 41756-41757 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T507 | 41798-41806 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T508 | 41834-41836 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
| T509 | 41882-41890 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T510 | 41912-41916 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T511 | 41988-41989 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T512 | 42051-42058 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T513 | 42161-42163 | http://purl.obolibrary.org/obo/CLO_0002105 | denotes | C2 |
| T514 | 42161-42163 | http://purl.obolibrary.org/obo/CLO_0051742 | denotes | C2 |
| T515 | 42196-42197 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T516 | 42299-42307 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T517 | 42398-42406 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T518 | 42531-42539 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T519 | 42561-42569 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptidic |
| T520 | 42580-42581 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T521 | 42711-42712 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T522 | 42890-42893 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T523 | 42924-42932 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T524 | 42939-42945 | http://purl.obolibrary.org/obo/NCBITaxon_33208 | denotes | animal |
| T525 | 42977-42982 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T526 | 43380-43386 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T527 | 43440-43446 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T528 | 43514-43519 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T529 | 43546-43548 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T530 | 43559-43562 | http://purl.obolibrary.org/obo/CLO_0007437 | denotes | M−1 |
| T531 | 43559-43562 | http://purl.obolibrary.org/obo/CLO_0007448 | denotes | M−1 |
| T532 | 43559-43562 | http://purl.obolibrary.org/obo/CLO_0007449 | denotes | M−1 |
| T533 | 43559-43562 | http://purl.obolibrary.org/obo/CLO_0050175 | denotes | M−1 |
| T534 | 43559-43562 | http://purl.obolibrary.org/obo/CLO_0052399 | denotes | M−1 |
| T535 | 43563-43566 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | s−1 |
| T536 | 43573-43580 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | Peptide |
| T537 | 43631-43632 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | Å |
| T538 | 43850-43851 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T539 | 43926-43931 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T540 | 43958-43959 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T541 | 44016-44017 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T542 | 44077-44078 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T543 | 44096-44097 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T544 | 44336-44337 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T545 | 44364-44365 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T546 | 44904-44905 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T547 | 45054-45058 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T548 | 45074-45084 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
| T549 | 45135-45141 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T550 | 45199-45205 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T551 | 45209-45228 | http://purl.obolibrary.org/obo/NCBITaxon_314147 | denotes | rodents and rabbits |
| T552 | 45471-45472 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T553 | 45473-45480 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T554 | 45486-45487 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T555 | 45570-45572 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T556 | 45627-45628 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T557 | 45697-45705 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T558 | 45729-45736 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T559 | 45746-45748 | http://purl.obolibrary.org/obo/CLO_0053794 | denotes | 41 |
| T560 | 45779-45787 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T561 | 45865-45875 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
| T562 | 46006-46011 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
| T563 | 46017-46022 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T564 | 46023-46029 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T565 | 46094-46099 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T566 | 46158-46165 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T567 | 46312-46319 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T568 | 46443-46447 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T569 | 46448-46456 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T570 | 46606-46614 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T571 | 46711-46719 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T572 | 46781-46786 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T573 | 46818-46823 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T574 | 46869-46877 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T575 | 46892-46897 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T576 | 46937-46938 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T577 | 47001-47008 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T578 | 47045-47046 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T579 | 47068-47071 | http://purl.obolibrary.org/obo/CLO_0037067 | denotes | Val |
| T580 | 47087-47090 | http://purl.obolibrary.org/obo/CLO_0002421 | denotes | CHO |
| T581 | 47087-47090 | http://purl.obolibrary.org/obo/CLO_0052479 | denotes | CHO |
| T582 | 47087-47090 | http://purl.obolibrary.org/obo/CLO_0052480 | denotes | CHO |
| T583 | 47087-47090 | http://purl.obolibrary.org/obo/CLO_0052483 | denotes | CHO |
| T584 | 47087-47090 | http://purl.obolibrary.org/obo/CLO_0052484 | denotes | CHO |
| T585 | 47087-47090 | http://purl.obolibrary.org/obo/CLO_0052485 | denotes | CHO |
| T586 | 47117-47125 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T587 | 47187-47189 | http://purl.obolibrary.org/obo/CLO_0008285 | denotes | P1 |
| T588 | 47223-47225 | http://purl.obolibrary.org/obo/CLO_0053799 | denotes | 45 |
| T589 | 47314-47316 | http://purl.obolibrary.org/obo/CLO_0008285 | denotes | P1 |
| T590 | 47319-47321 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T591 | 47328-47330 | http://purl.obolibrary.org/obo/CLO_0008337 | denotes | P4 |
| T592 | 47482-47490 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T593 | 47593-47599 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T594 | 47610-47612 | http://purl.obolibrary.org/obo/CLO_0008285 | denotes | P1 |
| T595 | 47645-47646 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T596 | 47718-47720 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T597 | 47760-47762 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T598 | 47760-47762 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T599 | 47807-47808 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T600 | 47898-47899 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T601 | 47916-47923 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T602 | 47946-47947 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T603 | 47989-47991 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T604 | 48023-48031 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptidic |
| T605 | 48058-48059 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T606 | 48140-48146 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T607 | 48190-48193 | http://purl.obolibrary.org/obo/CLO_0001079 | denotes | 148 |
| T608 | 48260-48262 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T609 | 48320-48322 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T610 | 48320-48322 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T611 | 48342-48344 | http://purl.obolibrary.org/obo/CLO_0008285 | denotes | P1 |
| T612 | 48375-48377 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T613 | 48514-48520 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T614 | 48538-48545 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | Peptide |
| T615 | 48745-48747 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T616 | 48745-48747 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T617 | 48777-48778 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T618 | 48799-48800 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T619 | 48828-48829 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T620 | 48908-48910 | http://purl.obolibrary.org/obo/CLO_0001407 | denotes | 52 |
| T621 | 48931-48933 | http://purl.obolibrary.org/obo/CLO_0001407 | denotes | 52 |
| T622 | 48985-48993 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T623 | 49061-49063 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T624 | 49061-49063 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T625 | 49092-49100 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T626 | 49221-49223 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T627 | 49221-49223 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T628 | 49248-49250 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T629 | 49464-49466 | http://purl.obolibrary.org/obo/CLO_0008285 | denotes | P1 |
| T630 | 49525-49531 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T631 | 49704-49708 | http://purl.obolibrary.org/obo/CLO_0001185 | denotes | 2018 |
| T632 | 49740-49741 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T633 | 49815-49819 | http://purl.obolibrary.org/obo/CLO_0001736 | denotes | a P3 |
| T634 | 49978-49979 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T635 | 50071-50076 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T636 | 50129-50137 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T637 | 50157-50161 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T638 | 50701-50705 | http://purl.obolibrary.org/obo/NCBITaxon_314295 | denotes | APEs |
| T639 | 50899-50902 | http://purl.obolibrary.org/obo/CLO_0007437 | denotes | M−1 |
| T640 | 50899-50902 | http://purl.obolibrary.org/obo/CLO_0007448 | denotes | M−1 |
| T641 | 50899-50902 | http://purl.obolibrary.org/obo/CLO_0007449 | denotes | M−1 |
| T642 | 50899-50902 | http://purl.obolibrary.org/obo/CLO_0050175 | denotes | M−1 |
| T643 | 50899-50902 | http://purl.obolibrary.org/obo/CLO_0052399 | denotes | M−1 |
| T644 | 50903-50906 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | s−1 |
| T645 | 50949-50957 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T646 | 51060-51061 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T647 | 51196-51204 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T648 | 51327-51329 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T649 | 51347-51356 | http://www.ebi.ac.uk/efo/EFO_0000876 | denotes | extremely |
| T650 | 51373-51381 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T651 | 51494-51502 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T652 | 51524-51528 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T653 | 51675-51676 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | Å |
| T654 | 51800-51801 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T655 | 51811-51812 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T656 | 51836-51842 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T657 | 51966-51968 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T658 | 52250-52255 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T5439 | 52816-52817 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T660 | 52973-52981 | http://purl.obolibrary.org/obo/CLO_0009985 | denotes | focusing |
| T661 | 52989-52991 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T662 | 53003-53004 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T663 | 53032-53034 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T664 | 53047-53049 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T665 | 53111-53113 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T666 | 53193-53197 | http://purl.obolibrary.org/obo/CLO_0009989 | denotes | Huh7 |
| T667 | 53198-53203 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T668 | 53237-53245 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T669 | 53277-53281 | http://purl.obolibrary.org/obo/CLO_0009524 | denotes | Vero |
| T670 | 53277-53281 | http://purl.obolibrary.org/obo/CLO_0050515 | denotes | Vero |
| T671 | 53282-53287 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T672 | 53302-53310 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T673 | 53389-53397 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T674 | 53406-53407 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T675 | 53442-53452 | http://purl.obolibrary.org/obo/CLO_0000031 | denotes | cell lines |
| T676 | 53582-53587 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T677 | 53645-53646 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T678 | 53853-53854 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T679 | 53925-53926 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T680 | 54046-54048 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T681 | 54100-54106 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T682 | 54216-54222 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T683 | 54260-54266 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T684 | 54492-54496 | http://purl.obolibrary.org/obo/CLO_0001577 | denotes | a ~3 |
| T685 | 54511-54517 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T686 | 54571-54573 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
| T687 | 54608-54614 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T688 | 54626-54629 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T689 | 54648-54649 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T690 | 54756-54757 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T691 | 54778-54780 | http://purl.obolibrary.org/obo/CLO_0053794 | denotes | 41 |
| T692 | 54836-54841 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
| T693 | 54842-54848 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T694 | 54941-54942 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T695 | 54956-54964 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T696 | 55070-55071 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T697 | 55110-55112 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T698 | 55147-55155 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T699 | 55473-55478 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T700 | 55479-55490 | http://purl.obolibrary.org/obo/CLO_0051840 | denotes | Calu3 cells |
| T701 | 55479-55490 | http://purl.obolibrary.org/obo/CLO_0051841 | denotes | Calu3 cells |
| T702 | 55479-55490 | http://purl.obolibrary.org/obo/CLO_0051842 | denotes | Calu3 cells |
| T703 | 55479-55490 | http://purl.obolibrary.org/obo/CLO_0051843 | denotes | Calu3 cells |
| T704 | 55479-55490 | http://purl.obolibrary.org/obo/CLO_0051844 | denotes | Calu3 cells |
| T705 | 55479-55484 | http://purl.obolibrary.org/obo/CLO_0002192 | denotes | Calu3 |
| T706 | 55543-55546 | http://purl.obolibrary.org/obo/CLO_0053799 | denotes | 4–5 |
| T707 | 55612-55613 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T708 | 55664-55672 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T709 | 55793-55799 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T710 | 55899-55903 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T711 | 55899-55903 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T712 | 56078-56079 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | Å |
| T713 | 56371-56372 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T714 | 56431-56432 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T715 | 56577-56579 | http://purl.obolibrary.org/obo/CLO_0008285 | denotes | P1 |
| T716 | 56620-56622 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T717 | 56664-56665 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T718 | 56782-56783 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T719 | 56806-56808 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T720 | 56842-56844 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T721 | 56842-56844 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T722 | 56861-56863 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T723 | 57117-57125 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T724 | 57384-57385 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T725 | 57433-57434 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T726 | 57485-57486 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T727 | 57620-57626 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T728 | 57691-57693 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T729 | 57703-57705 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T730 | 57707-57714 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | Peptide |
| T731 | 57857-57858 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T732 | 57895-57902 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T733 | 57925-57926 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T734 | 58005-58007 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
| T735 | 58041-58042 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T736 | 58056-58059 | http://purl.obolibrary.org/obo/CLO_0001046 | denotes | 116 |
| T737 | 58129-58137 | http://purl.obolibrary.org/obo/CLO_0009985 | denotes | focusing |
| T738 | 58183-58184 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T739 | 58255-58261 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T740 | 58317-58318 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T741 | 58319-58321 | http://purl.obolibrary.org/obo/CLO_0008285 | denotes | P1 |
| T742 | 58333-58335 | http://purl.obolibrary.org/obo/CLO_0008285 | denotes | P1 |
| T743 | 58358-58359 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T744 | 58392-58400 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T745 | 58502-58521 | http://purl.obolibrary.org/obo/CHEBI_33708 | denotes | amino acid residues |
| T746 | 58502-58521 | http://purl.obolibrary.org/obo/PR_000036907 | denotes | amino acid residues |
| T747 | 58644-58646 | http://purl.obolibrary.org/obo/CLO_0008285 | denotes | P1 |
| T748 | 58677-58679 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T749 | 58741-58742 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T750 | 58782-58783 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T751 | 58840-58842 | http://purl.obolibrary.org/obo/CLO_0008337 | denotes | P4 |
| T752 | 58851-58853 | http://purl.obolibrary.org/obo/CLO_0054055 | denotes | 71 |
| T753 | 58879-58888 | http://www.ebi.ac.uk/efo/EFO_0000876 | denotes | extremely |
| T754 | 58934-58935 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T755 | 58976-58978 | http://purl.obolibrary.org/obo/CLO_0054055 | denotes | 71 |
| T756 | 59043-59049 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T757 | 59104-59105 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T758 | 59236-59238 | http://purl.obolibrary.org/obo/CLO_0054055 | denotes | 71 |
| T759 | 59257-59258 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T760 | 59399-59407 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T761 | 59512-59513 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T762 | 59575-59577 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T763 | 59590-59592 | http://purl.obolibrary.org/obo/CLO_0008285 | denotes | P1 |
| T764 | 59874-59877 | http://purl.obolibrary.org/obo/CLO_0001002 | denotes | 162 |
| T765 | 60298-60299 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T766 | 60326-60327 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T767 | 60507-60508 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T768 | 60566-60569 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T769 | 60595-60602 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T770 | 60624-60626 | http://purl.obolibrary.org/obo/CLO_0008285 | denotes | P1 |
| T771 | 60630-60632 | http://purl.obolibrary.org/obo/CLO_0008337 | denotes | P4 |
| T772 | 60664-60672 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T773 | 60770-60773 | http://purl.obolibrary.org/obo/CLO_0001003 | denotes | 163 |
| T774 | 60797-60798 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T775 | 60926-60934 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T776 | 60947-60951 | http://purl.obolibrary.org/obo/CLO_0009524 | denotes | Vero |
| T777 | 60947-60951 | http://purl.obolibrary.org/obo/CLO_0050515 | denotes | Vero |
| T778 | 60956-60967 | http://purl.obolibrary.org/obo/CLO_0002172 | denotes | Caco‐2 cell |
| T779 | 61046-61047 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T780 | 61065-61072 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T781 | 61342-61343 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T782 | 61635-61636 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T783 | 61687-61688 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T784 | 62076-62077 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T785 | 62112-62118 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T786 | 62180-62182 | http://purl.obolibrary.org/obo/CLO_0008285 | denotes | P1 |
| T787 | 62244-62252 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T788 | 62281-62288 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T789 | 62578-62579 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T790 | 62960-62965 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T791 | 62983-62988 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T792 | 63290-63298 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T793 | 63317-63333 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity in cell |
| T794 | 63444-63446 | http://purl.obolibrary.org/obo/CLO_0007874 | denotes | MS |
| T795 | 63469-63475 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | Active |
| T796 | 63596-63597 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T797 | 63677-63678 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T798 | 63689-63695 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T799 | 63842-63850 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T800 | 63898-63906 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T801 | 64000-64002 | http://purl.obolibrary.org/obo/CLO_0007874 | denotes | MS |
| T802 | 64111-64112 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T803 | 64147-64149 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
| T804 | 64308-64316 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T805 | 64414-64418 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T806 | 64546-64548 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
| T807 | 64854-64859 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T808 | 64945-64946 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T809 | 65067-65068 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T810 | 65180-65183 | http://purl.obolibrary.org/obo/CLO_0054060 | denotes | 102 |
| T811 | 65268-65270 | http://purl.obolibrary.org/obo/CLO_0007874 | denotes | MS |
| T812 | 65340-65341 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T813 | 65848-65854 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T814 | 66503-66509 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tested |
| T815 | 66637-66645 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T816 | 66894-66900 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T817 | 67231-67234 | http://purl.obolibrary.org/obo/CLO_0001178 | denotes | 243 |
| T818 | 67231-67234 | http://purl.obolibrary.org/obo/CLO_0052433 | denotes | 243 |
| T819 | 67300-67308 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T820 | 67398-67406 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T821 | 67486-67492 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T822 | 67569-67570 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T823 | 67627-67635 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T824 | 67920-67923 | http://purl.obolibrary.org/obo/CLO_0054057 | denotes | 181 |
| T825 | 67948-67951 | http://purl.obolibrary.org/obo/CLO_0053001 | denotes | 114 |
| T826 | 68080-68088 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T827 | 68199-68201 | http://purl.obolibrary.org/obo/CLO_0037284 | denotes | C4 |
| T828 | 68264-68272 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T829 | 68386-68388 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T830 | 68818-68828 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
| T831 | 68848-68851 | http://purl.obolibrary.org/obo/CLO_0001046 | denotes | 116 |
| T832 | 68878-68886 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T833 | 68985-68986 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T834 | 69054-69057 | http://purl.obolibrary.org/obo/CLO_0001053 | denotes | 121 |
| T835 | 69069-69072 | http://purl.obolibrary.org/obo/CLO_0001053 | denotes | 121 |
| T836 | 69131-69134 | http://purl.obolibrary.org/obo/CLO_0054057 | denotes | 181 |
| T837 | 69168-69171 | http://purl.obolibrary.org/obo/CLO_0001230 | denotes | 293 |
| T838 | 69168-69171 | http://purl.obolibrary.org/obo/CLO_0037237 | denotes | 293 |
| T839 | 69168-69171 | http://purl.obolibrary.org/obo/CLO_0050903 | denotes | 293 |
| T840 | 69168-69171 | http://purl.obolibrary.org/obo/CLO_0054249 | denotes | 293 |
| T841 | 69168-69171 | http://purl.obolibrary.org/obo/CLO_0054250 | denotes | 293 |
| T842 | 69168-69171 | http://purl.obolibrary.org/obo/CLO_0054251 | denotes | 293 |
| T843 | 69168-69171 | http://purl.obolibrary.org/obo/CLO_0054252 | denotes | 293 |
| T844 | 69821-69823 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T845 | 70017-70018 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T846 | 70057-70058 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T847 | 70121-70129 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T848 | 70181-70194 | http://purl.obolibrary.org/obo/CLO_0051719 | denotes | Vero E6 cells |
| T849 | 70313-70315 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T850 | 70495-70503 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T851 | 70530-70532 | http://purl.obolibrary.org/obo/CLO_0008285 | denotes | P1 |
| T852 | 70627-70635 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T853 | 70686-70688 | http://purl.obolibrary.org/obo/CLO_0008285 | denotes | P1 |
| T854 | 70910-70911 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T855 | 71010-71011 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T856 | 71216-71224 | http://purl.obolibrary.org/obo/CLO_0009985 | denotes | focusing |
| T857 | 71286-71294 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T858 | 71399-71401 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T859 | 71458-71460 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T860 | 71461-71463 | http://purl.obolibrary.org/obo/CLO_0008285 | denotes | P1 |
| T861 | 71503-71504 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T862 | 71536-71537 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T863 | 71588-71591 | http://purl.obolibrary.org/obo/CLO_0054061 | denotes | 132 |
| T864 | 71796-71805 | http://www.ebi.ac.uk/efo/EFO_0000876 | denotes | extremely |
| T865 | 71943-71944 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T866 | 72100-72101 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T867 | 72321-72329 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T868 | 72458-72459 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T869 | 72601-72607 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T870 | 72812-72820 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T871 | 72947-72948 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T872 | 73148-73149 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T873 | 73350-73351 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T874 | 73509-73510 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T875 | 73556-73558 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
| T876 | 73700-73702 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
| T877 | 73947-73950 | http://purl.obolibrary.org/obo/CLO_0001079 | denotes | 148 |
| T878 | 74002-74003 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T879 | 74225-74233 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T880 | 74256-74258 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
| T881 | 74336-74345 | http://purl.obolibrary.org/obo/CLO_0009524 | denotes | Vero cell |
| T882 | 74420-74429 | http://purl.obolibrary.org/obo/CHEBI_28790 | denotes | serotonin |
| T883 | 74465-74467 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 35 |
| T884 | 74472-74473 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T885 | 74527-74535 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T886 | 74604-74609 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tests |
| T887 | 74639-74647 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T888 | 74718-74720 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 35 |
| T889 | 74963-74965 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 35 |
| T890 | 74974-74976 | http://purl.obolibrary.org/obo/CLO_0007874 | denotes | MS |
| T891 | 74977-74979 | http://purl.obolibrary.org/obo/CLO_0007874 | denotes | MS |
| T892 | 75210-75218 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T893 | 75454-75455 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T894 | 75550-75558 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T895 | 75611-75613 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 35 |
| T896 | 75623-75626 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T897 | 75669-75672 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T898 | 75673-75674 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T899 | 75724-75727 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T900 | 75816-75817 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T901 | 76336-76340 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T902 | 76461-76462 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T903 | 76489-76495 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T904 | 76510-76511 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T905 | 76581-76582 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T906 | 76610-76611 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T907 | 76881-76883 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
| T908 | 76914-76915 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T909 | 77011-77015 | http://purl.obolibrary.org/obo/CLO_0001757 | denotes | 1 at |
| T910 | 77016-77017 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T911 | 77123-77124 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T912 | 77505-77513 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T913 | 77550-77551 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T914 | 77587-77588 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T915 | 77660-77668 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T916 | 77672-77676 | http://purl.obolibrary.org/obo/CLO_0009524 | denotes | Vero |
| T917 | 77672-77676 | http://purl.obolibrary.org/obo/CLO_0050515 | denotes | Vero |
| T918 | 77677-77682 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T919 | 77721-77723 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
| T920 | 78044-78047 | http://purl.obolibrary.org/obo/CLO_0001003 | denotes | 163 |
| T921 | 78093-78096 | http://purl.obolibrary.org/obo/CLO_0001003 | denotes | 163 |
| T922 | 78137-78141 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T923 | 78159-78162 | http://purl.obolibrary.org/obo/CLO_0001003 | denotes | 163 |
| T924 | 78197-78207 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
| T925 | 78342-78350 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T926 | 78395-78403 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T927 | 78422-78426 | http://purl.obolibrary.org/obo/CLO_0009524 | denotes | Vero |
| T928 | 78422-78426 | http://purl.obolibrary.org/obo/CLO_0050515 | denotes | Vero |
| T929 | 78427-78432 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T930 | 78481-78482 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T931 | 78612-78613 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T932 | 78826-78834 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T933 | 78852-78856 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T934 | 78932-78940 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T935 | 78985-78993 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T936 | 79061-79065 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T937 | 79108-79110 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
| T938 | 79142-79152 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
| T939 | 79273-79281 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T940 | 79324-79337 | http://purl.obolibrary.org/obo/CLO_0001757 | denotes | 1 in the cell |
| T941 | 79441-79442 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T942 | 79509-79510 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T943 | 79754-79755 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T944 | 79818-79823 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T945 | 80176-80177 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T946 | 80409-80410 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T947 | 80440-80441 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T948 | 80916-80919 | http://purl.obolibrary.org/obo/CLO_0001180 | denotes | 203 |
| T949 | 80970-80978 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T950 | 81008-81009 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T951 | 81180-81181 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T952 | 81242-81244 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 35 |
| T953 | 81267-81268 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T954 | 81348-81354 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T955 | 81635-81640 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T956 | 81657-81664 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T957 | 81704-81711 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T958 | 81760-81761 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T959 | 81882-81889 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T960 | 81956-81957 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T961 | 82038-82042 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T962 | 82632-82635 | http://purl.obolibrary.org/obo/CLO_0054057 | denotes | 181 |
| T963 | 82856-82864 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T964 | 83063-83064 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T965 | 83266-83271 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T966 | 83389-83395 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T967 | 83592-83595 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T968 | 83635-83638 | http://purl.obolibrary.org/obo/CLO_0001195 | denotes | 219 |
| T969 | 83774-83775 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T970 | 83938-83939 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T971 | 83982-83990 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T972 | 83994-83995 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T973 | 84184-84191 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T974 | 84443-84448 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T975 | 84449-84455 | http://purl.obolibrary.org/obo/UBERON_0001005 | denotes | airway |
| T976 | 84456-84466 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
| T977 | 84473-84477 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T978 | 84502-84510 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T979 | 84575-84576 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T980 | 84695-84696 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T981 | 84697-84702 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
| T982 | 84770-84775 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T983 | 84797-84801 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T984 | 84797-84801 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T985 | 84986-84987 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T986 | 85110-85111 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T987 | 85156-85159 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T988 | 85208-85213 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T989 | 85335-85336 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T990 | 85446-85447 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T991 | 85727-85728 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T992 | 85799-85802 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T993 | 85859-85862 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T994 | 85921-85924 | http://purl.obolibrary.org/obo/CLO_0001196 | denotes | 225 |
| T995 | 86034-86035 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T996 | 86065-86068 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T997 | 86080-86088 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T998 | 86097-86098 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T999 | 86114-86121 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T1000 | 86224-86230 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T1001 | 86484-86485 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1002 | 86980-86983 | http://purl.obolibrary.org/obo/CLO_0001195 | denotes | 219 |
| T1003 | 87054-87055 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1004 | 87502-87503 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1005 | 87681-87684 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T1006 | 88121-88127 | http://purl.obolibrary.org/obo/NCBITaxon_33208 | denotes | animal |
| T1007 | 88280-88283 | http://purl.obolibrary.org/obo/CLO_0001203 | denotes | 232 |
| T1008 | 88325-88330 | http://purl.obolibrary.org/obo/CLO_0007225 | denotes | label |
| T1009 | 88519-88520 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T1010 | 88636-88641 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T1011 | 88712-88713 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1012 | 88922-88923 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1013 | 89012-89025 | http://purl.obolibrary.org/obo/CLO_0051719 | denotes | Vero E6 cells |
| T1014 | 89104-89105 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1015 | 89383-89387 | http://purl.obolibrary.org/obo/CLO_0009524 | denotes | Vero |
| T1016 | 89383-89387 | http://purl.obolibrary.org/obo/CLO_0050515 | denotes | Vero |
| T1017 | 89388-89393 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T1018 | 89534-89538 | http://purl.obolibrary.org/obo/CLO_0009524 | denotes | Vero |
| T1019 | 89534-89538 | http://purl.obolibrary.org/obo/CLO_0050515 | denotes | Vero |
| T1020 | 89539-89544 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T1021 | 89619-89622 | http://purl.obolibrary.org/obo/CLO_0001203 | denotes | 232 |
| T1022 | 89644-89647 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T1023 | 89679-89687 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T1024 | 89802-89803 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1025 | 89834-89835 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1026 | 89911-89912 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1027 | 89984-89985 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1028 | 89986-89995 | http://purl.obolibrary.org/obo/CHEBI_28790 | denotes | serotonin |
| T1029 | 90011-90012 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1030 | 90094-90095 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T1031 | 90186-90187 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1032 | 90311-90319 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T1033 | 90420-90422 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T1034 | 90425-90428 | http://purl.obolibrary.org/obo/CLO_0001053 | denotes | 121 |
| T1035 | 90564-90572 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T1036 | 91065-91082 | http://purl.obolibrary.org/obo/PR_000007204 | denotes | Estrogen receptor |
| T1037 | 91119-91136 | http://purl.obolibrary.org/obo/PR_000007204 | denotes | Estrogen receptor |
| T1038 | 92048-92057 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signaling |
| T1039 | 92099-92108 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signaling |
| T1040 | 92566-92576 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
| T1041 | 92888-92896 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T1042 | 93013-93023 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
| T1043 | 93189-93196 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T1044 | 93366-93383 | http://purl.obolibrary.org/obo/PR_000007204 | denotes | estrogen receptor |
| T1045 | 93489-93498 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signaling |
| T1046 | 93546-93552 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
| T1047 | 93735-93738 | http://purl.obolibrary.org/obo/CLO_0054057 | denotes | 181 |
| T1048 | 93806-93814 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T1049 | 93961-93965 | http://purl.obolibrary.org/obo/CLO_0001757 | denotes | 1 at |
| T1050 | 94060-94073 | http://purl.obolibrary.org/obo/CLO_0051719 | denotes | Vero E6 cells |
| T1051 | 94138-94146 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T1052 | 94169-94171 | http://purl.obolibrary.org/obo/CLO_0001382 | denotes | 48 |
| T1053 | 94356-94358 | http://purl.obolibrary.org/obo/CLO_0001382 | denotes | 48 |
| T1054 | 94402-94403 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1055 | 94439-94443 | http://purl.obolibrary.org/obo/CLO_0009524 | denotes | Vero |
| T1056 | 94439-94443 | http://purl.obolibrary.org/obo/CLO_0050515 | denotes | Vero |
| T1057 | 94444-94449 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T1058 | 94674-94677 | http://purl.obolibrary.org/obo/CLO_0054057 | denotes | 181 |
| T1059 | 94742-94752 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
| T1060 | 94761-94766 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T1061 | 94782-94786 | http://purl.obolibrary.org/obo/CLO_0009524 | denotes | Vero |
| T1062 | 94782-94786 | http://purl.obolibrary.org/obo/CLO_0050515 | denotes | Vero |
| T1063 | 94787-94792 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T1064 | 94838-94846 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T1065 | 95127-95128 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1066 | 95198-95199 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T1067 | 95259-95260 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1068 | 95310-95311 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T1069 | 95389-95391 | http://purl.obolibrary.org/obo/CLO_0037161 | denotes | en |
| T1070 | 95511-95519 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T1071 | 95546-95547 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1072 | 95738-95739 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1073 | 95871-95876 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T1074 | 95877-95881 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T1075 | 95877-95881 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T1076 | 95965-95968 | http://purl.obolibrary.org/obo/CLO_0001178 | denotes | 243 |
| T1077 | 95965-95968 | http://purl.obolibrary.org/obo/CLO_0052433 | denotes | 243 |
| T1078 | 96159-96162 | http://purl.obolibrary.org/obo/PR_000001343 | denotes | aim |
| T1079 | 96194-96198 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T1080 | 96194-96198 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T1081 | 96252-96255 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T1082 | 96273-96274 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1083 | 96309-96310 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1084 | 96443-96444 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1085 | 96462-96465 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T1086 | 96489-96490 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1087 | 96544-96545 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1088 | 96582-96583 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1089 | 96630-96631 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1090 | 96686-96691 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T1091 | 96686-96691 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T1092 | 96801-96802 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1093 | 96827-96828 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1094 | 96879-96897 | http://purl.obolibrary.org/obo/UBERON_0002012 | denotes | pulmonary arterial |
| T1095 | 96879-96897 | http://www.ebi.ac.uk/efo/EFO_0001399 | denotes | pulmonary arterial |
| T1096 | 97006-97007 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1097 | 97008-97013 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T1098 | 97008-97013 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T1099 | 97088-97089 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1100 | 97223-97227 | http://purl.obolibrary.org/obo/CLO_0009524 | denotes | Vero |
| T1101 | 97223-97227 | http://purl.obolibrary.org/obo/CLO_0050515 | denotes | Vero |
| T1102 | 97228-97233 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T1103 | 97488-97494 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tested |
| T1104 | 97598-97601 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 3–6 |
| T1105 | 97678-97679 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1106 | 97749-97755 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tested |
| T1107 | 99033-99034 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1108 | 99289-99290 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1109 | 99437-99438 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T1110 | 99482-99486 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T1111 | 99550-99553 | http://purl.obolibrary.org/obo/CLO_0054060 | denotes | 102 |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1 | 719-724 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T2 | 849-865 | Chemical | denotes | antiviral agents | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T3 | 1021-1033 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T4 | 1151-1159 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T5 | 1264-1275 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T6 | 1303-1312 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T7 | 1313-1316 | Chemical | denotes | ADA | http://purl.obolibrary.org/obo/CHEBI_39048 |
| T8 | 1317-1326 | Chemical | denotes | adenosine | http://purl.obolibrary.org/obo/CHEBI_16335 |
| T9 | 1337-1340 | Chemical | denotes | Ang | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T10 | 1341-1352 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T11 | 1357-1368 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T12 | 1445-1448 | Chemical | denotes | DPP | http://purl.obolibrary.org/obo/CHEBI_34680|http://purl.obolibrary.org/obo/CHEBI_60069 |
| T14 | 1474-1476 | Chemical | denotes | MS | http://purl.obolibrary.org/obo/CHEBI_73613 |
| T15 | 1652-1654 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T17 | 2089-2095 | Chemical | denotes | serine | http://purl.obolibrary.org/obo/CHEBI_17822 |
| T18 | 5183-5194 | Chemical | denotes | nucleotides | http://purl.obolibrary.org/obo/CHEBI_36976 |
| T19 | 5274-5282 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T20 | 5480-5488 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T21 | 5582-5595 | Chemical | denotes | glycoproteins | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T22 | 5833-5845 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T23 | 6013-6020 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T24 | 6169-6180 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T25 | 6361-6372 | Chemical | denotes | sialic acid | http://purl.obolibrary.org/obo/CHEBI_26667 |
| T26 | 6368-6372 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T27 | 7020-7044 | Chemical | denotes | O‐Acetylated sialic acid | http://purl.obolibrary.org/obo/CHEBI_28879 |
| T28 | 7033-7044 | Chemical | denotes | sialic acid | http://purl.obolibrary.org/obo/CHEBI_26667 |
| T29 | 7040-7044 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T30 | 7072-7096 | Chemical | denotes | O‐Acetylated sialic acid | http://purl.obolibrary.org/obo/CHEBI_28879 |
| T31 | 7085-7096 | Chemical | denotes | sialic acid | http://purl.obolibrary.org/obo/CHEBI_26667 |
| T32 | 7092-7096 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T33 | 7682-7689 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T34 | 7767-7769 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T35 | 7840-7842 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T36 | 7899-7905 | Chemical | denotes | serine | http://purl.obolibrary.org/obo/CHEBI_17822 |
| T37 | 8293-8301 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T38 | 8506-8514 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T39 | 8697-8705 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T40 | 8831-8839 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T41 | 8851-8863 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T42 | 8878-8886 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T43 | 8897-8905 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T44 | 8932-8940 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T45 | 9161-9169 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T46 | 9209-9217 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T47 | 9625-9627 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T49 | 9632-9634 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T51 | 9638-9640 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T53 | 9644-9646 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T55 | 9662-9665 | Chemical | denotes | MCP | http://purl.obolibrary.org/obo/CHEBI_132592|http://purl.obolibrary.org/obo/CHEBI_50099 |
| T57 | 9710-9718 | Chemical | denotes | effector | http://purl.obolibrary.org/obo/CHEBI_35224 |
| T58 | 9946-9953 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T59 | 9954-9961 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T60 | 10042-10050 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T61 | 10078-10084 | Chemical | denotes | ligand | http://purl.obolibrary.org/obo/CHEBI_52214 |
| T62 | 10137-10145 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T63 | 10156-10168 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T64 | 10421-10430 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T65 | 10436-10440 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T66 | 10512-10522 | Chemical | denotes | antivirals | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T67 | 10722-10729 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T68 | 11044-11051 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T69 | 11058-11068 | Chemical | denotes | nucleotide | http://purl.obolibrary.org/obo/CHEBI_36976 |
| T70 | 11181-11188 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T71 | 11222-11229 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T72 | 11795-11797 | Chemical | denotes | EM | http://purl.obolibrary.org/obo/CHEBI_73507 |
| T73 | 11864-11866 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T74 | 11927-11929 | Chemical | denotes | EM | http://purl.obolibrary.org/obo/CHEBI_73507 |
| T75 | 11941-11949 | Chemical | denotes | electron | http://purl.obolibrary.org/obo/CHEBI_10545 |
| T76 | 12257-12262 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T77 | 12536-12538 | Chemical | denotes | EM | http://purl.obolibrary.org/obo/CHEBI_73507 |
| T78 | 12729-12736 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T79 | 12809-12816 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T80 | 12841-12843 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T81 | 13253-13255 | Chemical | denotes | EM | http://purl.obolibrary.org/obo/CHEBI_73507 |
| T82 | 13360-13368 | Chemical | denotes | hydrogen | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T83 | 13901-13911 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T84 | 14054-14063 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T85 | 14166-14172 | Chemical | denotes | ligand | http://purl.obolibrary.org/obo/CHEBI_52214 |
| T86 | 14380-14385 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T87 | 14404-14409 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T88 | 14418-14428 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T89 | 14491-14502 | Chemical | denotes | amino acids | http://purl.obolibrary.org/obo/CHEBI_33709 |
| T90 | 14491-14496 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T91 | 14497-14502 | Chemical | denotes | acids | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T92 | 14713-14721 | Chemical | denotes | peptides | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T93 | 14774-14781 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T94 | 14959-14967 | Chemical | denotes | peptides | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T95 | 14968-14970 | Chemical | denotes | P4 | http://purl.obolibrary.org/obo/CHEBI_35895 |
| T96 | 15068-15077 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T97 | 15133-15140 | Chemical | denotes | glycine | http://purl.obolibrary.org/obo/CHEBI_15428|http://purl.obolibrary.org/obo/CHEBI_29947|http://purl.obolibrary.org/obo/CHEBI_57305 |
| T100 | 15160-15167 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T101 | 15168-15170 | Chemical | denotes | P4 | http://purl.obolibrary.org/obo/CHEBI_35895 |
| T102 | 15209-15216 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T103 | 15446-15448 | Chemical | denotes | EM | http://purl.obolibrary.org/obo/CHEBI_73507 |
| T104 | 15543-15550 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T105 | 15603-15610 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T106 | 15686-15695 | Chemical | denotes | adenosine | http://purl.obolibrary.org/obo/CHEBI_16335 |
| T107 | 15717-15724 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T108 | 15837-15839 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T109 | 15854-15866 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T110 | 15949-15959 | Chemical | denotes | dipeptides | http://purl.obolibrary.org/obo/CHEBI_46761 |
| T111 | 16544-16555 | Chemical | denotes | amino acids | http://purl.obolibrary.org/obo/CHEBI_33709 |
| T112 | 16544-16549 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T113 | 16550-16555 | Chemical | denotes | acids | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T114 | 16679-16686 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T115 | 16730-16737 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T116 | 16752-16772 | Chemical | denotes | HIV fusion inhibitor | http://purl.obolibrary.org/obo/CHEBI_59886 |
| T117 | 16763-16772 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T118 | 16837-16845 | Chemical | denotes | peptides | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T119 | 16861-16871 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T120 | 16878-16887 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T121 | 16965-16973 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T122 | 17212-17219 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T123 | 17273-17283 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T124 | 17350-17358 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T125 | 17365-17375 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T126 | 17440-17448 | Chemical | denotes | peptides | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T127 | 17450-17458 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T128 | 17481-17490 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T129 | 17638-17645 | Chemical | denotes | oxazole | http://purl.obolibrary.org/obo/CHEBI_35597|http://purl.obolibrary.org/obo/CHEBI_35790 |
| T131 | 17646-17657 | Chemical | denotes | carboxamide | http://purl.obolibrary.org/obo/CHEBI_23004|http://purl.obolibrary.org/obo/CHEBI_37622 |
| T133 | 17704-17713 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T134 | 17802-17811 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T135 | 18108-18117 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T136 | 18141-18149 | Chemical | denotes | luteolin | http://purl.obolibrary.org/obo/CHEBI_15864|http://purl.obolibrary.org/obo/CHEBI_57545 |
| T138 | 18204-18206 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T139 | 18207-18214 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T140 | 18389-18391 | Chemical | denotes | SI | http://purl.obolibrary.org/obo/CHEBI_90326 |
| T141 | 18613-18622 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T142 | 18684-18693 | Chemical | denotes | Quercetin | http://purl.obolibrary.org/obo/CHEBI_16243 |
| T143 | 18737-18746 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T144 | 18859-18862 | Chemical | denotes | ADS | http://purl.obolibrary.org/obo/CHEBI_73344 |
| T145 | 18918-18927 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T146 | 19139-19148 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T147 | 19170-19177 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T148 | 19779-19786 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T149 | 19818-19828 | Chemical | denotes | amino acid | http://purl.obolibrary.org/obo/CHEBI_33709 |
| T150 | 19818-19823 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T151 | 19824-19828 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T152 | 19881-19888 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T153 | 19907-19914 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T154 | 20091-20098 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T155 | 20139-20150 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T156 | 20152-20155 | Chemical | denotes | Ang | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T157 | 20234-20237 | Chemical | denotes | Ang | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T158 | 20238-20246 | Chemical | denotes | peptides | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T159 | 20327-20330 | Chemical | denotes | Ang | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T160 | 20354-20357 | Chemical | denotes | Ang | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T161 | 20358-20360 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T162 | 20377-20386 | Chemical | denotes | dipeptide | http://purl.obolibrary.org/obo/CHEBI_46761 |
| T163 | 20391-20394 | Chemical | denotes | Leu | http://purl.obolibrary.org/obo/CHEBI_15603|http://purl.obolibrary.org/obo/CHEBI_25017|http://purl.obolibrary.org/obo/CHEBI_30006 |
| T166 | 20401-20404 | Chemical | denotes | Ang | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T167 | 20405-20407 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T168 | 20665-20675 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T169 | 20688-20702 | Chemical | denotes | angiotensin II | http://purl.obolibrary.org/obo/CHEBI_2719|http://purl.obolibrary.org/obo/CHEBI_48432|http://purl.obolibrary.org/obo/CHEBI_58506 |
| T172 | 20688-20699 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T173 | 20700-20702 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T174 | 20774-20777 | Chemical | denotes | Ang | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T175 | 20778-20780 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T176 | 20844-20855 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T177 | 20890-20901 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T178 | 20910-20918 | Chemical | denotes | peptides | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T179 | 20976-20987 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T180 | 21001-21012 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T181 | 21116-21120 | Chemical | denotes | zinc | http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185 |
| T183 | 21176-21186 | Chemical | denotes | amino acid | http://purl.obolibrary.org/obo/CHEBI_33709 |
| T184 | 21176-21181 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T185 | 21182-21186 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T186 | 21231-21249 | Chemical | denotes | amino acid residue | http://purl.obolibrary.org/obo/CHEBI_33708 |
| T187 | 21231-21241 | Chemical | denotes | amino acid | http://purl.obolibrary.org/obo/CHEBI_33709 |
| T188 | 21231-21236 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T189 | 21237-21241 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T190 | 21251-21254 | Chemical | denotes | Leu | http://purl.obolibrary.org/obo/CHEBI_15603|http://purl.obolibrary.org/obo/CHEBI_25017|http://purl.obolibrary.org/obo/CHEBI_30006 |
| T193 | 21258-21261 | Chemical | denotes | Phe | http://purl.obolibrary.org/obo/CHEBI_17295|http://purl.obolibrary.org/obo/CHEBI_29997 |
| T195 | 21268-21271 | Chemical | denotes | Ang | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T196 | 21278-21281 | Chemical | denotes | Ang | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T197 | 21282-21284 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T198 | 21311-21314 | Chemical | denotes | Ang | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T199 | 21325-21328 | Chemical | denotes | Ang | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T200 | 21338-21349 | Chemical | denotes | vasodilator | http://purl.obolibrary.org/obo/CHEBI_35620 |
| T201 | 21608-21617 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T202 | 21637-21646 | Chemical | denotes | aziridine | http://purl.obolibrary.org/obo/CHEBI_30969 |
| T203 | 21647-21657 | Chemical | denotes | ethanamine | http://purl.obolibrary.org/obo/CHEBI_15862 |
| T204 | 21872-21883 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T205 | 21959-21970 | Chemical | denotes | Chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T206 | 22116-22125 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T207 | 22412-22423 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T208 | 22489-22491 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T210 | 22561-22572 | Chemical | denotes | Chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T211 | 22947-22958 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T212 | 23208-23219 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T213 | 23599-23610 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T214 | 23611-23620 | Chemical | denotes | phosphate | http://purl.obolibrary.org/obo/CHEBI_18367|http://purl.obolibrary.org/obo/CHEBI_26020|http://purl.obolibrary.org/obo/CHEBI_35780|http://purl.obolibrary.org/obo/CHEBI_43474 |
| T218 | 23782-23786 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T219 | 23940-23958 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
| T220 | 23963-23975 | Chemical | denotes | azithromycin | http://purl.obolibrary.org/obo/CHEBI_2955 |
| T221 | 24219-24237 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
| T222 | 24281-24293 | Chemical | denotes | azithromycin | http://purl.obolibrary.org/obo/CHEBI_2955 |
| T223 | 24407-24425 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
| T224 | 24476-24488 | Chemical | denotes | azithromycin | http://purl.obolibrary.org/obo/CHEBI_2955 |
| T225 | 24735-24740 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T226 | 24791-24796 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T227 | 24881-24892 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T228 | 24912-24930 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
| T229 | 25130-25134 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T230 | 25289-25307 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
| T231 | 25311-25322 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T232 | 25365-25374 | Chemical | denotes | macrolide | http://purl.obolibrary.org/obo/CHEBI_25106 |
| T233 | 25383-25395 | Chemical | denotes | azithromycin | http://purl.obolibrary.org/obo/CHEBI_2955 |
| T234 | 25400-25414 | Chemical | denotes | clarithromycin | http://purl.obolibrary.org/obo/CHEBI_3732 |
| T235 | 25514-25518 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T236 | 25692-25697 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T237 | 25791-25802 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T238 | 25807-25825 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
| T239 | 25991-26009 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
| T240 | 26426-26435 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T241 | 26491-26501 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T242 | 26762-26770 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T243 | 26771-26780 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T244 | 26926-26930 | Chemical | denotes | zinc | http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185 |
| T246 | 26965-26972 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T247 | 26986-26995 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T248 | 27125-27132 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T249 | 27260-27274 | Chemical | denotes | antiviral drug | http://purl.obolibrary.org/obo/CHEBI_36044 |
| T250 | 27260-27269 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T251 | 27270-27274 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T252 | 28210-28215 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T253 | 28361-28364 | Chemical | denotes | ACC | http://purl.obolibrary.org/obo/CHEBI_18053|http://purl.obolibrary.org/obo/CHEBI_30526 |
| T255 | 28365-28368 | Chemical | denotes | AHA | http://purl.obolibrary.org/obo/CHEBI_27777 |
| T256 | 28842-28852 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T257 | 29079-29086 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T258 | 29354-29361 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T259 | 29738-29745 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T260 | 29756-29758 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T261 | 29791-29798 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T262 | 30069-30075 | Chemical | denotes | serine | http://purl.obolibrary.org/obo/CHEBI_17822 |
| T263 | 30177-30193 | Chemical | denotes | neurotransmitter | http://purl.obolibrary.org/obo/CHEBI_25512 |
| T264 | 30212-30226 | Chemical | denotes | chlorpromazine | http://purl.obolibrary.org/obo/CHEBI_3647 |
| T265 | 30233-30245 | Chemical | denotes | promethazine | http://purl.obolibrary.org/obo/CHEBI_8461 |
| T266 | 30256-30268 | Chemical | denotes | fluphenazine | http://purl.obolibrary.org/obo/CHEBI_5123 |
| T267 | 30362-30369 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T268 | 30391-30405 | Chemical | denotes | Chlorpromazine | http://purl.obolibrary.org/obo/CHEBI_3647 |
| T269 | 30439-30448 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T270 | 30649-30659 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T271 | 30755-30780 | Chemical | denotes | serine protease inhibitor | http://purl.obolibrary.org/obo/CHEBI_64926 |
| T272 | 30755-30761 | Chemical | denotes | serine | http://purl.obolibrary.org/obo/CHEBI_17822 |
| T273 | 30762-30780 | Chemical | denotes | protease inhibitor | http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258 |
| T275 | 30771-30780 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T276 | 30781-30789 | Chemical | denotes | camostat | http://purl.obolibrary.org/obo/CHEBI_135632 |
| T277 | 30824-30833 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T278 | 30959-30966 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T279 | 31180-31189 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T280 | 31345-31351 | Chemical | denotes | serine | http://purl.obolibrary.org/obo/CHEBI_17822 |
| T281 | 31563-31572 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T282 | 31757-31784 | Chemical | denotes | cysteine protease inhibitor | http://purl.obolibrary.org/obo/CHEBI_64152 |
| T283 | 31757-31765 | Chemical | denotes | cysteine | http://purl.obolibrary.org/obo/CHEBI_15356 |
| T284 | 31766-31784 | Chemical | denotes | protease inhibitor | http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258 |
| T286 | 31775-31784 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T287 | 31992-32001 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T288 | 32062-32074 | Chemical | denotes | glycopeptide | http://purl.obolibrary.org/obo/CHEBI_24396 |
| T289 | 32075-32085 | Chemical | denotes | antibiotic | http://purl.obolibrary.org/obo/CHEBI_33281 |
| T290 | 32146-32157 | Chemical | denotes | methicillin | http://purl.obolibrary.org/obo/CHEBI_6827 |
| T291 | 32235-32246 | Chemical | denotes | teicoplanin | http://purl.obolibrary.org/obo/CHEBI_29687 |
| T292 | 32478-32489 | Chemical | denotes | teicoplanin | http://purl.obolibrary.org/obo/CHEBI_29687 |
| T293 | 32579-32588 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T294 | 32592-32614 | Chemical | denotes | cathepsin L inhibitors | http://purl.obolibrary.org/obo/CHEBI_70821 |
| T295 | 32604-32614 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T296 | 32638-32646 | Chemical | denotes | cysteine | http://purl.obolibrary.org/obo/CHEBI_15356 |
| T297 | 32730-32737 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T298 | 32826-32835 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T299 | 33002-33011 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T300 | 33273-33295 | Chemical | denotes | Cathepsin L inhibitors | http://purl.obolibrary.org/obo/CHEBI_70821 |
| T301 | 33285-33295 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T302 | 33301-33310 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T303 | 33409-33419 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T304 | 34008-34017 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T305 | 34290-34300 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T306 | 34397-34401 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T307 | 34560-34566 | Chemical | denotes | emodin | http://purl.obolibrary.org/obo/CHEBI_42223|http://purl.obolibrary.org/obo/CHEBI_77659 |
| T309 | 34686-34693 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T310 | 34769-34776 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T311 | 34962-34971 | Chemical | denotes | benzamide | http://purl.obolibrary.org/obo/CHEBI_28179 |
| T312 | 35055-35064 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T313 | 35248-35257 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T314 | 35467-35476 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T315 | 36039-36047 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T316 | 36071-36079 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T317 | 36277-36292 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T318 | 36282-36292 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T319 | 36358-36366 | Chemical | denotes | cysteine | http://purl.obolibrary.org/obo/CHEBI_15356 |
| T320 | 36448-36450 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T321 | 36680-36688 | Chemical | denotes | cysteine | http://purl.obolibrary.org/obo/CHEBI_15356 |
| T322 | 36701-36712 | Chemical | denotes | nucleophile | http://purl.obolibrary.org/obo/CHEBI_59740 |
| T323 | 36738-36747 | Chemical | denotes | histidine | http://purl.obolibrary.org/obo/CHEBI_27570 |
| T324 | 36767-36771 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T325 | 36772-36776 | Chemical | denotes | base | http://purl.obolibrary.org/obo/CHEBI_22695 |
| T326 | 36782-36789 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T327 | 36803-36812 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T328 | 36852-36854 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T329 | 36988-37007 | Chemical | denotes | protease inhibitors | http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258 |
| T331 | 36997-37007 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T332 | 37045-37049 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T333 | 37112-37127 | Chemical | denotes | peptidomimetics | http://purl.obolibrary.org/obo/CHEBI_63175 |
| T334 | 37144-37153 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T335 | 37272-37281 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T336 | 37485-37500 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T337 | 37490-37500 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T338 | 37522-37527 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T339 | 37803-37813 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T340 | 37930-37939 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T341 | 38010-38018 | Chemical | denotes | cysteine | http://purl.obolibrary.org/obo/CHEBI_15356 |
| T342 | 38069-38076 | Chemical | denotes | Peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T343 | 38077-38087 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T344 | 38125-38130 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T345 | 38154-38159 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T346 | 38164-38172 | Chemical | denotes | peptides | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T347 | 38219-38226 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T348 | 38333-38351 | Chemical | denotes | amino acid residue | http://purl.obolibrary.org/obo/CHEBI_33708 |
| T349 | 38333-38343 | Chemical | denotes | amino acid | http://purl.obolibrary.org/obo/CHEBI_33709 |
| T350 | 38333-38338 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T351 | 38339-38343 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T352 | 38447-38462 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T353 | 38452-38462 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T354 | 38628-38636 | Chemical | denotes | acceptor | http://purl.obolibrary.org/obo/CHEBI_15339 |
| T355 | 38650-38655 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T356 | 38752-38761 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T357 | 38762-38765 | Chemical | denotes | Cbz | http://purl.obolibrary.org/obo/CHEBI_51097 |
| T358 | 38766-38769 | Chemical | denotes | Val | http://purl.obolibrary.org/obo/CHEBI_16414|http://purl.obolibrary.org/obo/CHEBI_30015 |
| T360 | 38770-38773 | Chemical | denotes | Asn | http://purl.obolibrary.org/obo/CHEBI_17196|http://purl.obolibrary.org/obo/CHEBI_22653|http://purl.obolibrary.org/obo/CHEBI_50347 |
| T363 | 38774-38777 | Chemical | denotes | Ser | http://purl.obolibrary.org/obo/CHEBI_17115|http://purl.obolibrary.org/obo/CHEBI_29999 |
| T365 | 38778-38781 | Chemical | denotes | Thr | http://purl.obolibrary.org/obo/CHEBI_16857|http://purl.obolibrary.org/obo/CHEBI_30013 |
| T367 | 38782-38785 | Chemical | denotes | Leu | http://purl.obolibrary.org/obo/CHEBI_15603|http://purl.obolibrary.org/obo/CHEBI_25017|http://purl.obolibrary.org/obo/CHEBI_30006 |
| T370 | 38786-38789 | Chemical | denotes | Gln | http://purl.obolibrary.org/obo/CHEBI_30011 |
| T371 | 38803-38809 | Chemical | denotes | ketone | http://purl.obolibrary.org/obo/CHEBI_17087 |
| T372 | 38850-38856 | Chemical | denotes | ketone | http://purl.obolibrary.org/obo/CHEBI_17087 |
| T373 | 39054-39056 | Chemical | denotes | P1 | http://purl.obolibrary.org/obo/CHEBI_60949 |
| T374 | 39057-39060 | Chemical | denotes | Gln | http://purl.obolibrary.org/obo/CHEBI_30011 |
| T375 | 39120-39122 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
| T376 | 39123-39130 | Chemical | denotes | leucine | http://purl.obolibrary.org/obo/CHEBI_25017 |
| T377 | 39162-39164 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T378 | 39232-39246 | Chemical | denotes | peptidomimetic | http://purl.obolibrary.org/obo/CHEBI_63175 |
| T379 | 39247-39256 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T380 | 39312-39321 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T381 | 39376-39385 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T382 | 39447-39462 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T383 | 39452-39462 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T384 | 39555-39564 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T385 | 39743-39745 | Chemical | denotes | P1 | http://purl.obolibrary.org/obo/CHEBI_60949 |
| T386 | 39746-39752 | Chemical | denotes | lactam | http://purl.obolibrary.org/obo/CHEBI_24995 |
| T387 | 39771-39777 | Chemical | denotes | phenyl | http://purl.obolibrary.org/obo/CHEBI_30396 |
| T388 | 39843-39845 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
| T389 | 39881-39893 | Chemical | denotes | phenyl group | http://purl.obolibrary.org/obo/CHEBI_30396 |
| T390 | 39888-39893 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T391 | 39970-39979 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T392 | 40028-40030 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
| T393 | 40046-40051 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T394 | 40090-40092 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
| T395 | 40093-40099 | Chemical | denotes | benzyl | http://purl.obolibrary.org/obo/CHEBI_22744 |
| T396 | 40439-40444 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T397 | 40466-40474 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T398 | 40500-40502 | Chemical | denotes | P4 | http://purl.obolibrary.org/obo/CHEBI_35895 |
| T399 | 40503-40506 | Chemical | denotes | Boc | http://purl.obolibrary.org/obo/CHEBI_48502 |
| T400 | 40507-40513 | Chemical | denotes | serine | http://purl.obolibrary.org/obo/CHEBI_17822 |
| T401 | 40539-40547 | Chemical | denotes | hydrogen | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T402 | 40709-40723 | Chemical | denotes | isobutyl group | http://purl.obolibrary.org/obo/CHEBI_30356 |
| T403 | 40718-40723 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T404 | 40752-40757 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T405 | 40853-40868 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T406 | 40858-40868 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T407 | 40888-40896 | Chemical | denotes | acceptor | http://purl.obolibrary.org/obo/CHEBI_15339 |
| T408 | 40910-40915 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T409 | 41051-41058 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T410 | 41059-41069 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T411 | 41161-41170 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T412 | 41299-41301 | Chemical | denotes | P1 | http://purl.obolibrary.org/obo/CHEBI_60949 |
| T413 | 41302-41313 | Chemical | denotes | lactam ring | http://purl.obolibrary.org/obo/CHEBI_77730 |
| T414 | 41302-41308 | Chemical | denotes | lactam | http://purl.obolibrary.org/obo/CHEBI_24995 |
| T415 | 41389-41397 | Chemical | denotes | hydrogen | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T416 | 41478-41480 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
| T417 | 41481-41488 | Chemical | denotes | leucine | http://purl.obolibrary.org/obo/CHEBI_25017 |
| T418 | 41558-41560 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
| T419 | 41561-41574 | Chemical | denotes | phenylalanine | http://purl.obolibrary.org/obo/CHEBI_28044|http://purl.obolibrary.org/obo/CHEBI_58095 |
| T421 | 41625-41630 | Chemical | denotes | butyl | http://purl.obolibrary.org/obo/CHEBI_41264 |
| T422 | 41691-41697 | Chemical | denotes | valine | http://purl.obolibrary.org/obo/CHEBI_27266 |
| T423 | 41732-41734 | Chemical | denotes | P4 | http://purl.obolibrary.org/obo/CHEBI_35895 |
| T424 | 41758-41773 | Chemical | denotes | benzyloxy group | http://purl.obolibrary.org/obo/CHEBI_48508 |
| T425 | 41768-41773 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T426 | 41872-41881 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T427 | 41957-41966 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T428 | 41998-42006 | Chemical | denotes | acceptor | http://purl.obolibrary.org/obo/CHEBI_15339 |
| T429 | 42051-42058 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T430 | 42059-42069 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T431 | 42126-42130 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T432 | 42161-42163 | Chemical | denotes | C2 | http://purl.obolibrary.org/obo/CHEBI_30083 |
| T433 | 42174-42184 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T434 | 42198-42201 | Chemical | denotes | Phe | http://purl.obolibrary.org/obo/CHEBI_17295|http://purl.obolibrary.org/obo/CHEBI_29997 |
| T436 | 42202-42205 | Chemical | denotes | Phe | http://purl.obolibrary.org/obo/CHEBI_17295|http://purl.obolibrary.org/obo/CHEBI_29997 |
| T438 | 42233-42238 | Chemical | denotes | ester | http://purl.obolibrary.org/obo/CHEBI_35701 |
| T439 | 42253-42263 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T440 | 42388-42397 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T441 | 42470-42483 | Chemical | denotes | dimethylamine | http://purl.obolibrary.org/obo/CHEBI_17170|http://purl.obolibrary.org/obo/CHEBI_58040 |
| T443 | 42491-42497 | Chemical | denotes | phenyl | http://purl.obolibrary.org/obo/CHEBI_30396 |
| T444 | 42570-42574 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T445 | 42590-42598 | Chemical | denotes | acceptor | http://purl.obolibrary.org/obo/CHEBI_15339 |
| T446 | 42728-42737 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T447 | 42914-42923 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T448 | 43360-43375 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T449 | 43365-43375 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T450 | 43573-43580 | Chemical | denotes | Peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T451 | 43782-43785 | Chemical | denotes | Cys | http://purl.obolibrary.org/obo/CHEBI_15356|http://purl.obolibrary.org/obo/CHEBI_17561|http://purl.obolibrary.org/obo/CHEBI_29950 |
| T454 | 43877-43879 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T455 | 43996-44005 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T456 | 44314-44324 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T457 | 44346-44354 | Chemical | denotes | acceptor | http://purl.obolibrary.org/obo/CHEBI_15339 |
| T458 | 44355-44360 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T459 | 44443-44459 | Chemical | denotes | cysteine residue | http://purl.obolibrary.org/obo/CHEBI_32460 |
| T460 | 44443-44451 | Chemical | denotes | cysteine | http://purl.obolibrary.org/obo/CHEBI_15356 |
| T461 | 44508-44524 | Chemical | denotes | cysteine residue | http://purl.obolibrary.org/obo/CHEBI_32460 |
| T462 | 44508-44516 | Chemical | denotes | cysteine | http://purl.obolibrary.org/obo/CHEBI_15356 |
| T463 | 44575-44583 | Chemical | denotes | acceptor | http://purl.obolibrary.org/obo/CHEBI_15339 |
| T464 | 44584-44589 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T465 | 44714-44723 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T466 | 44732-44748 | Chemical | denotes | cysteine residue | http://purl.obolibrary.org/obo/CHEBI_32460 |
| T467 | 44732-44740 | Chemical | denotes | cysteine | http://purl.obolibrary.org/obo/CHEBI_15356 |
| T468 | 44774-44784 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T469 | 44798-44806 | Chemical | denotes | acceptor | http://purl.obolibrary.org/obo/CHEBI_15339 |
| T470 | 44807-44812 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T471 | 44892-44900 | Chemical | denotes | aldehyde | http://purl.obolibrary.org/obo/CHEBI_17478 |
| T472 | 44914-44919 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T473 | 44949-44959 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T474 | 44998-45003 | Chemical | denotes | vinyl | http://purl.obolibrary.org/obo/CHEBI_37603 |
| T475 | 45004-45015 | Chemical | denotes | ethyl ester | http://purl.obolibrary.org/obo/CHEBI_23990 |
| T476 | 45004-45009 | Chemical | denotes | ethyl | http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801 |
| T478 | 45010-45015 | Chemical | denotes | ester | http://purl.obolibrary.org/obo/CHEBI_35701 |
| T479 | 45115-45131 | Chemical | denotes | carboxylic acids | http://purl.obolibrary.org/obo/CHEBI_33575 |
| T480 | 45126-45131 | Chemical | denotes | acids | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T481 | 45363-45371 | Chemical | denotes | acceptor | http://purl.obolibrary.org/obo/CHEBI_15339 |
| T482 | 45378-45387 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T483 | 45473-45480 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T484 | 45502-45510 | Chemical | denotes | cysteine | http://purl.obolibrary.org/obo/CHEBI_15356 |
| T485 | 45520-45525 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T486 | 45533-45544 | Chemical | denotes | an aldehyde | http://purl.obolibrary.org/obo/CHEBI_17478 |
| T487 | 45570-45572 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
| T488 | 45573-45580 | Chemical | denotes | leucine | http://purl.obolibrary.org/obo/CHEBI_25017 |
| T489 | 45629-45639 | Chemical | denotes | cyclohexyl | http://purl.obolibrary.org/obo/CHEBI_52552 |
| T490 | 45649-45663 | Chemical | denotes | aldehyde group | http://purl.obolibrary.org/obo/CHEBI_42485 |
| T491 | 45649-45657 | Chemical | denotes | aldehyde | http://purl.obolibrary.org/obo/CHEBI_17478 |
| T492 | 45658-45663 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T493 | 45729-45736 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T494 | 45737-45745 | Chemical | denotes | aldehyde | http://purl.obolibrary.org/obo/CHEBI_17478 |
| T495 | 45855-45864 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T496 | 46137-46152 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T497 | 46142-46152 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T498 | 46158-46165 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T499 | 46166-46174 | Chemical | denotes | aldehyde | http://purl.obolibrary.org/obo/CHEBI_17478 |
| T500 | 46312-46319 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T501 | 46320-46328 | Chemical | denotes | aldehyde | http://purl.obolibrary.org/obo/CHEBI_17478 |
| T502 | 46329-46339 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T503 | 46473-46488 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T504 | 46478-46488 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T505 | 46701-46710 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T506 | 46859-46868 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T507 | 46960-46975 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T508 | 46965-46975 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T509 | 47001-47008 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T510 | 47047-47059 | Chemical | denotes | pentapeptide | http://purl.obolibrary.org/obo/CHEBI_48545 |
| T511 | 47061-47063 | Chemical | denotes | Ac | http://purl.obolibrary.org/obo/CHEBI_33337|http://purl.obolibrary.org/obo/CHEBI_40574 |
| T513 | 47064-47067 | Chemical | denotes | Ser | http://purl.obolibrary.org/obo/CHEBI_17115|http://purl.obolibrary.org/obo/CHEBI_29999 |
| T515 | 47068-47071 | Chemical | denotes | Val | http://purl.obolibrary.org/obo/CHEBI_16414|http://purl.obolibrary.org/obo/CHEBI_30015 |
| T517 | 47072-47075 | Chemical | denotes | Leu | http://purl.obolibrary.org/obo/CHEBI_15603|http://purl.obolibrary.org/obo/CHEBI_25017|http://purl.obolibrary.org/obo/CHEBI_30006 |
| T520 | 47166-47175 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T521 | 47187-47189 | Chemical | denotes | P1 | http://purl.obolibrary.org/obo/CHEBI_60949 |
| T522 | 47190-47199 | Chemical | denotes | imidazole | http://purl.obolibrary.org/obo/CHEBI_14434|http://purl.obolibrary.org/obo/CHEBI_16069 |
| T524 | 47314-47316 | Chemical | denotes | P1 | http://purl.obolibrary.org/obo/CHEBI_60949 |
| T525 | 47319-47321 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
| T526 | 47328-47330 | Chemical | denotes | P4 | http://purl.obolibrary.org/obo/CHEBI_35895 |
| T527 | 47394-47403 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T528 | 47442-47451 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T529 | 47610-47612 | Chemical | denotes | P1 | http://purl.obolibrary.org/obo/CHEBI_60949 |
| T530 | 47613-47622 | Chemical | denotes | imidazole | http://purl.obolibrary.org/obo/CHEBI_14434|http://purl.obolibrary.org/obo/CHEBI_16069 |
| T532 | 47623-47636 | Chemical | denotes | nitrogen atom | http://purl.obolibrary.org/obo/CHEBI_25555|http://purl.obolibrary.org/obo/CHEBI_29351 |
| T534 | 47632-47636 | Chemical | denotes | atom | http://purl.obolibrary.org/obo/CHEBI_33250 |
| T535 | 47647-47655 | Chemical | denotes | hydrogen | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T536 | 47670-47679 | Chemical | denotes | histidine | http://purl.obolibrary.org/obo/CHEBI_27570 |
| T537 | 47690-47699 | Chemical | denotes | imidazole | http://purl.obolibrary.org/obo/CHEBI_14434|http://purl.obolibrary.org/obo/CHEBI_16069 |
| T539 | 47700-47708 | Chemical | denotes | nitrogen | http://purl.obolibrary.org/obo/CHEBI_25555 |
| T540 | 47718-47720 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
| T541 | 47721-47731 | Chemical | denotes | cyclohexyl | http://purl.obolibrary.org/obo/CHEBI_52552 |
| T542 | 47760-47762 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T543 | 47821-47830 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T544 | 47882-47887 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T545 | 47916-47923 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T546 | 47924-47934 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T547 | 47989-47991 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
| T548 | 47992-48002 | Chemical | denotes | cyclohexyl | http://purl.obolibrary.org/obo/CHEBI_52552 |
| T549 | 48046-48056 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T550 | 48260-48262 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
| T551 | 48320-48322 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T552 | 48342-48344 | Chemical | denotes | P1 | http://purl.obolibrary.org/obo/CHEBI_60949 |
| T553 | 48345-48354 | Chemical | denotes | imidazole | http://purl.obolibrary.org/obo/CHEBI_14434|http://purl.obolibrary.org/obo/CHEBI_16069 |
| T555 | 48486-48491 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T556 | 48538-48545 | Chemical | denotes | Peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T557 | 48546-48556 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T558 | 48568-48578 | Chemical | denotes | cyclohexyl | http://purl.obolibrary.org/obo/CHEBI_52552 |
| T559 | 48672-48677 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T560 | 48715-48725 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T561 | 48745-48747 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T562 | 48751-48753 | Chemical | denotes | S4 | http://purl.obolibrary.org/obo/CHEBI_29401 |
| T563 | 49061-49063 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T564 | 49064-49066 | Chemical | denotes | S4 | http://purl.obolibrary.org/obo/CHEBI_29401 |
| T565 | 49137-49142 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T566 | 49221-49223 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T567 | 49248-49250 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
| T568 | 49374-49382 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T569 | 49464-49466 | Chemical | denotes | P1 | http://purl.obolibrary.org/obo/CHEBI_60949 |
| T570 | 49467-49476 | Chemical | denotes | imidazole | http://purl.obolibrary.org/obo/CHEBI_14434|http://purl.obolibrary.org/obo/CHEBI_16069 |
| T572 | 49492-49500 | Chemical | denotes | aldehyde | http://purl.obolibrary.org/obo/CHEBI_17478 |
| T573 | 49512-49517 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T574 | 49558-49563 | Chemical | denotes | butyl | http://purl.obolibrary.org/obo/CHEBI_41264 |
| T27514 | 49786-49801 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T82575 | 49791-49801 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T95892 | 49820-49830 | Chemical | denotes | piperidine | http://purl.obolibrary.org/obo/CHEBI_18049|http://purl.obolibrary.org/obo/CHEBI_589779 |
| T26260 | 49864-49874 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T5217 | 49908-49916 | Chemical | denotes | aldehyde | http://purl.obolibrary.org/obo/CHEBI_17478 |
| T51366 | 49917-49926 | Chemical | denotes | bisulfite | http://purl.obolibrary.org/obo/CHEBI_17137 |
| T39371 | 49980-49998 | Chemical | denotes | protease inhibitor | http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258 |
| T4181 | 49989-49998 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T24510 | 50119-50128 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T26289 | 50249-50259 | Chemical | denotes | piperidine | http://purl.obolibrary.org/obo/CHEBI_18049|http://purl.obolibrary.org/obo/CHEBI_589779 |
| T4261 | 50320-50322 | Chemical | denotes | S3 | http://purl.obolibrary.org/obo/CHEBI_29388 |
| T7439 | 50327-50329 | Chemical | denotes | S4 | http://purl.obolibrary.org/obo/CHEBI_29401 |
| T16 | 50382-50390 | Chemical | denotes | aldehyde | http://purl.obolibrary.org/obo/CHEBI_17478 |
| T2957 | 50392-50400 | Chemical | denotes | aldehyde | http://purl.obolibrary.org/obo/CHEBI_17478 |
| T41973 | 50401-50410 | Chemical | denotes | bisulfite | http://purl.obolibrary.org/obo/CHEBI_17137 |
| T28623 | 50423-50430 | Chemical | denotes | epoxide | http://purl.obolibrary.org/obo/CHEBI_32955 |
| T56252 | 50439-50444 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T17852 | 50509-50518 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T34518 | 50538-50548 | Chemical | denotes | piperidine | http://purl.obolibrary.org/obo/CHEBI_18049|http://purl.obolibrary.org/obo/CHEBI_589779 |
| T78419 | 50586-50588 | Chemical | denotes | S4 | http://purl.obolibrary.org/obo/CHEBI_29401 |
| T18768 | 50691-50699 | Chemical | denotes | epoxides | http://purl.obolibrary.org/obo/CHEBI_32955 |
| T82413 | 50739-50754 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T80325 | 50744-50754 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T76046 | 50805-50807 | Chemical | denotes | CD | http://purl.obolibrary.org/obo/CHEBI_8673 |
| T31193 | 50808-50816 | Chemical | denotes | cysteine | http://purl.obolibrary.org/obo/CHEBI_15356 |
| T36285 | 50845-50852 | Chemical | denotes | epoxide | http://purl.obolibrary.org/obo/CHEBI_32955 |
| T21892 | 51088-51096 | Chemical | denotes | cysteine | http://purl.obolibrary.org/obo/CHEBI_15356 |
| T33497 | 51099-51103 | Chemical | denotes | atom | http://purl.obolibrary.org/obo/CHEBI_33250 |
| T11527 | 51112-51119 | Chemical | denotes | epoxide | http://purl.obolibrary.org/obo/CHEBI_32955 |
| T73113 | 51168-51175 | Chemical | denotes | epoxide | http://purl.obolibrary.org/obo/CHEBI_32955 |
| T71965 | 51267-51281 | Chemical | denotes | peptidomimetic | http://purl.obolibrary.org/obo/CHEBI_63175 |
| T35724 | 51293-51308 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T19702 | 51298-51308 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T43475 | 51464-51469 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T3504 | 51484-51493 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T21346 | 51755-51764 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T52951 | 51781-51789 | Chemical | denotes | aldehyde | http://purl.obolibrary.org/obo/CHEBI_17478 |
| T20290 | 51996-52011 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T46510 | 52001-52011 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T87241 | 52020-52026 | Chemical | denotes | indole | http://purl.obolibrary.org/obo/CHEBI_16881|http://purl.obolibrary.org/obo/CHEBI_35581 |
| T49684 | 52130-52140 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T75940 | 52203-52219 | Chemical | denotes | antiviral agents | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T48 | 52336-52341 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T77441 | 52376-52384 | Chemical | denotes | hydrogen | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T50 | 52435-52440 | Chemical | denotes | amide | http://purl.obolibrary.org/obo/CHEBI_29337|http://purl.obolibrary.org/obo/CHEBI_32988 |
| T52 | 52441-52447 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
| T41687 | 52494-52502 | Chemical | denotes | acceptor | http://purl.obolibrary.org/obo/CHEBI_15339 |
| T54 | 52503-52509 | Chemical | denotes | esters | http://purl.obolibrary.org/obo/CHEBI_35701 |
| T91863 | 52514-52523 | Chemical | denotes | aldehydes | http://purl.obolibrary.org/obo/CHEBI_17478 |
| T56 | 52542-52550 | Chemical | denotes | hydrogen | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T21097 | 52556-52564 | Chemical | denotes | acceptor | http://purl.obolibrary.org/obo/CHEBI_15339 |
| T61862 | 52605-52619 | Chemical | denotes | Mpro inhibitor | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T94981 | 52610-52619 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T52612 | 52688-52698 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T45586 | 52989-52991 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
| T62151 | 53032-53034 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
| T56998 | 53035-53041 | Chemical | denotes | phenyl | http://purl.obolibrary.org/obo/CHEBI_30396 |
| T20063 | 53047-53049 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
| T27961 | 53050-53060 | Chemical | denotes | cyclohexyl | http://purl.obolibrary.org/obo/CHEBI_52552 |
| T86938 | 53111-53113 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
| T75961 | 53114-53125 | Chemical | denotes | cyclopentyl | http://purl.obolibrary.org/obo/CHEBI_52880 |
| T61372 | 53227-53236 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T896 | 53292-53301 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T87883 | 53379-53388 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T7603 | 53633-53641 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T40736 | 53658-53672 | Chemical | denotes | Mpro inhibitor | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T97159 | 53663-53672 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T77172 | 54046-54048 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
| T56473 | 54052-54057 | Chemical | denotes | amide | http://purl.obolibrary.org/obo/CHEBI_29337|http://purl.obolibrary.org/obo/CHEBI_32988 |
| T64629 | 54072-54080 | Chemical | denotes | pyridone | http://purl.obolibrary.org/obo/CHEBI_38183 |
| T15402 | 54190-54199 | Chemical | denotes | Boc group | http://purl.obolibrary.org/obo/CHEBI_48502 |
| T58006 | 54194-54199 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T93511 | 54267-54275 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T65337 | 54849-54856 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T67050 | 55072-55089 | Chemical | denotes | cyclopropyl group | http://purl.obolibrary.org/obo/CHEBI_30364 |
| T89827 | 55084-55089 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T1382 | 55110-55112 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
| T4101 | 55113-55123 | Chemical | denotes | cyclohexyl | http://purl.obolibrary.org/obo/CHEBI_52552 |
| T93196 | 55137-55146 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T26920 | 55568-55571 | Chemical | denotes | Boc | http://purl.obolibrary.org/obo/CHEBI_48502 |
| T18812 | 55632-55637 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T15971 | 55734-55743 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T72808 | 55800-55807 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T45343 | 56159-56168 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T93415 | 56268-56270 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T52365 | 56343-56352 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T9616 | 56404-56409 | Chemical | denotes | amide | http://purl.obolibrary.org/obo/CHEBI_29337|http://purl.obolibrary.org/obo/CHEBI_32988 |
| T14214 | 56410-56416 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
| T69815 | 56460-56466 | Chemical | denotes | amides | http://purl.obolibrary.org/obo/CHEBI_32988 |
| T98 | 56523-56531 | Chemical | denotes | cysteine | http://purl.obolibrary.org/obo/CHEBI_15356 |
| T99 | 56577-56579 | Chemical | denotes | P1 | http://purl.obolibrary.org/obo/CHEBI_60949 |
| T1465 | 56580-56586 | Chemical | denotes | lactam | http://purl.obolibrary.org/obo/CHEBI_24995 |
| T49981 | 56640-56646 | Chemical | denotes | lactam | http://purl.obolibrary.org/obo/CHEBI_24995 |
| T46088 | 56647-56655 | Chemical | denotes | nitrogen | http://purl.obolibrary.org/obo/CHEBI_25555 |
| T71910 | 56704-56710 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
| T13154 | 56760-56768 | Chemical | denotes | carbonyl | http://purl.obolibrary.org/obo/CHEBI_23019 |
| T5593 | 56769-56775 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
| T19001 | 56806-56808 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
| T90582 | 56809-56820 | Chemical | denotes | cyclopropyl | http://purl.obolibrary.org/obo/CHEBI_30364 |
| T32008 | 56842-56844 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T30690 | 56861-56863 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
| T77042 | 56864-56872 | Chemical | denotes | pyridone | http://purl.obolibrary.org/obo/CHEBI_38183 |
| T17126 | 56950-56959 | Chemical | denotes | Boc group | http://purl.obolibrary.org/obo/CHEBI_48502 |
| T6537 | 56954-56959 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T7038 | 56993-56995 | Chemical | denotes | S4 | http://purl.obolibrary.org/obo/CHEBI_29401 |
| T76426 | 57074-57083 | Chemical | denotes | Boc group | http://purl.obolibrary.org/obo/CHEBI_48502 |
| T65557 | 57078-57083 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T649 | 57354-57360 | Chemical | denotes | ketone | http://purl.obolibrary.org/obo/CHEBI_17087 |
| T33650 | 57398-57404 | Chemical | denotes | ketone | http://purl.obolibrary.org/obo/CHEBI_17087 |
| T37304 | 57512-57521 | Chemical | denotes | hemiketal | http://purl.obolibrary.org/obo/CHEBI_59772 |
| T45902 | 57568-57571 | Chemical | denotes | Ser | http://purl.obolibrary.org/obo/CHEBI_17115|http://purl.obolibrary.org/obo/CHEBI_29999 |
| T36506 | 57578-57581 | Chemical | denotes | Cys | http://purl.obolibrary.org/obo/CHEBI_15356|http://purl.obolibrary.org/obo/CHEBI_17561|http://purl.obolibrary.org/obo/CHEBI_29950 |
| T42212 | 57582-57584 | Chemical | denotes | SH | http://purl.obolibrary.org/obo/CHEBI_29312|http://purl.obolibrary.org/obo/CHEBI_73651 |
| T45833 | 57636-57642 | Chemical | denotes | serine | http://purl.obolibrary.org/obo/CHEBI_17822 |
| T24832 | 57646-57654 | Chemical | denotes | cysteine | http://purl.obolibrary.org/obo/CHEBI_15356 |
| T10610 | 57707-57714 | Chemical | denotes | Peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T27374 | 57715-57725 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T130 | 57751-57757 | Chemical | denotes | ketone | http://purl.obolibrary.org/obo/CHEBI_17087 |
| T49997 | 57895-57902 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T132 | 57903-57913 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T3406 | 57927-57942 | Chemical | denotes | trifluoromethyl | http://purl.obolibrary.org/obo/CHEBI_50127 |
| T60315 | 57943-57949 | Chemical | denotes | ketone | http://purl.obolibrary.org/obo/CHEBI_17087 |
| T59718 | 58239-58247 | Chemical | denotes | cysteine | http://purl.obolibrary.org/obo/CHEBI_15356 |
| T18276 | 58319-58321 | Chemical | denotes | P1 | http://purl.obolibrary.org/obo/CHEBI_60949 |
| T137 | 58322-58328 | Chemical | denotes | lactam | http://purl.obolibrary.org/obo/CHEBI_24995 |
| T80163 | 58333-58335 | Chemical | denotes | P1 | http://purl.obolibrary.org/obo/CHEBI_60949 |
| T28014 | 58337-58345 | Chemical | denotes | thiazole | http://purl.obolibrary.org/obo/CHEBI_43732|http://purl.obolibrary.org/obo/CHEBI_48901 |
| T13260 | 58502-58512 | Chemical | denotes | amino acid | http://purl.obolibrary.org/obo/CHEBI_33709 |
| T23846 | 58502-58507 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T21836 | 58508-58512 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T66042 | 58554-58567 | Chemical | denotes | nitrogen atom | http://purl.obolibrary.org/obo/CHEBI_25555|http://purl.obolibrary.org/obo/CHEBI_29351 |
| T7803 | 58563-58567 | Chemical | denotes | atom | http://purl.obolibrary.org/obo/CHEBI_33250 |
| T34611 | 58575-58583 | Chemical | denotes | thiazole | http://purl.obolibrary.org/obo/CHEBI_43732|http://purl.obolibrary.org/obo/CHEBI_48901 |
| T29375 | 58644-58646 | Chemical | denotes | P1 | http://purl.obolibrary.org/obo/CHEBI_60949 |
| T28695 | 58647-58653 | Chemical | denotes | lactam | http://purl.obolibrary.org/obo/CHEBI_24995 |
| T92289 | 58743-58753 | Chemical | denotes | tripeptide | http://purl.obolibrary.org/obo/CHEBI_47923 |
| T52382 | 58765-58778 | Chemical | denotes | benzothiazole | http://purl.obolibrary.org/obo/CHEBI_45993 |
| T54961 | 58792-58797 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T54093 | 58831-58836 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T50478 | 58840-58842 | Chemical | denotes | P4 | http://purl.obolibrary.org/obo/CHEBI_35895 |
| T91497 | 58998-59011 | Chemical | denotes | benzothiazole | http://purl.obolibrary.org/obo/CHEBI_45993 |
| T52567 | 59012-59017 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T58318 | 59088-59093 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T37981 | 59116-59126 | Chemical | denotes | dipeptides | http://purl.obolibrary.org/obo/CHEBI_46761 |
| T97726 | 59182-59186 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T92052 | 59211-59217 | Chemical | denotes | valine | http://purl.obolibrary.org/obo/CHEBI_27266 |
| T38814 | 59225-59235 | Chemical | denotes | tripeptide | http://purl.obolibrary.org/obo/CHEBI_47923 |
| T9588 | 59463-59468 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T164 | 59469-59477 | Chemical | denotes | hydrogen | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T165 | 59490-59496 | Chemical | denotes | phenyl | http://purl.obolibrary.org/obo/CHEBI_30396 |
| T22453 | 59497-59503 | Chemical | denotes | glycyl | http://purl.obolibrary.org/obo/CHEBI_29947|http://purl.obolibrary.org/obo/CHEBI_46740 |
| T7278 | 59575-59577 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
| T6255 | 59578-59585 | Chemical | denotes | leucine | http://purl.obolibrary.org/obo/CHEBI_25017 |
| T170 | 59590-59592 | Chemical | denotes | P1 | http://purl.obolibrary.org/obo/CHEBI_60949 |
| T171 | 59706-59712 | Chemical | denotes | indole | http://purl.obolibrary.org/obo/CHEBI_16881|http://purl.obolibrary.org/obo/CHEBI_35581 |
| T78384 | 59715-59729 | Chemical | denotes | carbonyl group | http://purl.obolibrary.org/obo/CHEBI_23019 |
| T55500 | 59724-59729 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T91926 | 59779-59789 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T7771 | 59944-59950 | Chemical | denotes | indole | http://purl.obolibrary.org/obo/CHEBI_16881|http://purl.obolibrary.org/obo/CHEBI_35581 |
| T81173 | 59951-59956 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T92675 | 59957-59965 | Chemical | denotes | hydrogen | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T52035 | 59974-59988 | Chemical | denotes | carbonyl group | http://purl.obolibrary.org/obo/CHEBI_23019 |
| T73981 | 59983-59988 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T182 | 60169-60183 | Chemical | denotes | carbonyl group | http://purl.obolibrary.org/obo/CHEBI_23019 |
| T30382 | 60178-60183 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T73351 | 60223-60229 | Chemical | denotes | indole | http://purl.obolibrary.org/obo/CHEBI_16881|http://purl.obolibrary.org/obo/CHEBI_35581 |
| T70252 | 60235-60245 | Chemical | denotes | benzofuran | http://purl.obolibrary.org/obo/CHEBI_36790 |
| T18292 | 60519-60534 | Chemical | denotes | trifluoromethyl | http://purl.obolibrary.org/obo/CHEBI_50127 |
| T41093 | 60535-60542 | Chemical | denotes | ketones | http://purl.obolibrary.org/obo/CHEBI_17087 |
| T98772 | 60595-60602 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T41746 | 60624-60626 | Chemical | denotes | P1 | http://purl.obolibrary.org/obo/CHEBI_60949 |
| T191 | 60630-60632 | Chemical | denotes | P4 | http://purl.obolibrary.org/obo/CHEBI_35895 |
| T192 | 60809-60819 | Chemical | denotes | dipeptides | http://purl.obolibrary.org/obo/CHEBI_46761 |
| T81044 | 60846-60852 | Chemical | denotes | ketone | http://purl.obolibrary.org/obo/CHEBI_17087 |
| T194 | 60867-60882 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T2879 | 60872-60882 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T43478 | 61065-61072 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T40437 | 61153-61163 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T68978 | 61369-61378 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T42650 | 61439-61447 | Chemical | denotes | dimethyl | http://purl.obolibrary.org/obo/CHEBI_33601|http://purl.obolibrary.org/obo/CHEBI_42266 |
| T90668 | 61448-61453 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T13186 | 61461-61467 | Chemical | denotes | phenyl | http://purl.obolibrary.org/obo/CHEBI_30396 |
| T89789 | 61478-61486 | Chemical | denotes | electron | http://purl.obolibrary.org/obo/CHEBI_10545 |
| T69586 | 61521-61527 | Chemical | denotes | phenyl | http://purl.obolibrary.org/obo/CHEBI_30396 |
| T73849 | 61667-61678 | Chemical | denotes | tripeptides | http://purl.obolibrary.org/obo/CHEBI_47923 |
| T93299 | 61713-61718 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T37065 | 61760-61775 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T61902 | 61765-61775 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T209 | 61914-61919 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T48448 | 61978-61986 | Chemical | denotes | hydrogen | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T62153 | 61999-62013 | Chemical | denotes | carbonyl group | http://purl.obolibrary.org/obo/CHEBI_23019 |
| T63490 | 62008-62013 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T40231 | 62098-62101 | Chemical | denotes | Cys | http://purl.obolibrary.org/obo/CHEBI_15356|http://purl.obolibrary.org/obo/CHEBI_17561|http://purl.obolibrary.org/obo/CHEBI_29950 |
| T216 | 62102-62104 | Chemical | denotes | SH | http://purl.obolibrary.org/obo/CHEBI_29312|http://purl.obolibrary.org/obo/CHEBI_73651 |
| T7763 | 62180-62182 | Chemical | denotes | P1 | http://purl.obolibrary.org/obo/CHEBI_60949 |
| T45344 | 62183-62189 | Chemical | denotes | lactam | http://purl.obolibrary.org/obo/CHEBI_24995 |
| T96378 | 62199-62210 | Chemical | denotes | nitro group | http://purl.obolibrary.org/obo/CHEBI_29785 |
| T18132 | 62205-62210 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T44225 | 62281-62288 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T18237 | 62316-62327 | Chemical | denotes | tripeptides | http://purl.obolibrary.org/obo/CHEBI_47923 |
| T40825 | 62342-62352 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T20685 | 62492-62507 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T65888 | 62497-62507 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T90232 | 62535-62545 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T34371 | 62601-62610 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T22085 | 62795-62801 | Chemical | denotes | indole | http://purl.obolibrary.org/obo/CHEBI_16881|http://purl.obolibrary.org/obo/CHEBI_35581 |
| T12666 | 62802-62807 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T27348 | 62900-62915 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T35234 | 62905-62915 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T95534 | 62943-62953 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T2987 | 63081-63089 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T67003 | 63090-63100 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T41984 | 63123-63129 | Chemical | denotes | esters | http://purl.obolibrary.org/obo/CHEBI_35701 |
| T15863 | 63199-63209 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T76768 | 63307-63316 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T59369 | 63444-63446 | Chemical | denotes | MS | http://purl.obolibrary.org/obo/CHEBI_73613 |
| T57087 | 63476-63482 | Chemical | denotes | esters | http://purl.obolibrary.org/obo/CHEBI_35701 |
| T1438 | 63497-63512 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T85249 | 63502-63512 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T33732 | 63634-63647 | Chemical | denotes | benzotriazole | http://purl.obolibrary.org/obo/CHEBI_75331 |
| T245 | 63648-63653 | Chemical | denotes | ester | http://purl.obolibrary.org/obo/CHEBI_35701 |
| T79350 | 63708-63714 | Chemical | denotes | esters | http://purl.obolibrary.org/obo/CHEBI_35701 |
| T5859 | 63726-63735 | Chemical | denotes | thiophene | http://purl.obolibrary.org/obo/CHEBI_30856 |
| T72146 | 63737-63742 | Chemical | denotes | furan | http://purl.obolibrary.org/obo/CHEBI_35559 |
| T52453 | 63748-63754 | Chemical | denotes | indole | http://purl.obolibrary.org/obo/CHEBI_16881|http://purl.obolibrary.org/obo/CHEBI_35581 |
| T96213 | 63888-63897 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T97418 | 64000-64002 | Chemical | denotes | MS | http://purl.obolibrary.org/obo/CHEBI_73613 |
| T89322 | 64076-64082 | Chemical | denotes | indole | http://purl.obolibrary.org/obo/CHEBI_16881|http://purl.obolibrary.org/obo/CHEBI_35581 |
| T24837 | 64165-64180 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T66246 | 64170-64180 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T32608 | 64298-64307 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T94953 | 64462-64470 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T6907 | 64571-64577 | Chemical | denotes | indole | http://purl.obolibrary.org/obo/CHEBI_16881|http://purl.obolibrary.org/obo/CHEBI_35581 |
| T89170 | 64605-64620 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T17573 | 64610-64620 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T64398 | 64715-64721 | Chemical | denotes | esters | http://purl.obolibrary.org/obo/CHEBI_35701 |
| T16685 | 64738-64742 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T97378 | 64920-64926 | Chemical | denotes | thiols | http://purl.obolibrary.org/obo/CHEBI_29256 |
| T11735 | 64931-64943 | Chemical | denotes | nucleophiles | http://purl.obolibrary.org/obo/CHEBI_59740 |
| T77735 | 65028-65038 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T49664 | 65069-65074 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T1032 | 65078-65087 | Chemical | denotes | methylene | http://purl.obolibrary.org/obo/CHEBI_29357|http://purl.obolibrary.org/obo/CHEBI_29358|http://purl.obolibrary.org/obo/CHEBI_50728 |
| T11556 | 65088-65095 | Chemical | denotes | ketones | http://purl.obolibrary.org/obo/CHEBI_17087 |
| T88640 | 65135-65144 | Chemical | denotes | methylene | http://purl.obolibrary.org/obo/CHEBI_29357|http://purl.obolibrary.org/obo/CHEBI_29358|http://purl.obolibrary.org/obo/CHEBI_50728 |
| T70579 | 65145-65152 | Chemical | denotes | ketones | http://purl.obolibrary.org/obo/CHEBI_17087 |
| T67480 | 65162-65171 | Chemical | denotes | pyridinyl | http://purl.obolibrary.org/obo/CHEBI_51635 |
| T79188 | 65172-65178 | Chemical | denotes | esters | http://purl.obolibrary.org/obo/CHEBI_35701 |
| T68953 | 65218-65233 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T12741 | 65223-65233 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T14743 | 65268-65270 | Chemical | denotes | MS | http://purl.obolibrary.org/obo/CHEBI_73613 |
| T94708 | 65305-65315 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T95032 | 65395-65399 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T75474 | 65404-65410 | Chemical | denotes | isatin | http://purl.obolibrary.org/obo/CHEBI_27539 |
| T285 | 65437-65452 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T81531 | 65442-65452 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T5212 | 65597-65611 | Chemical | denotes | etacrynic acid | http://purl.obolibrary.org/obo/CHEBI_4876 |
| T80310 | 65607-65611 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T60378 | 65620-65625 | Chemical | denotes | amide | http://purl.obolibrary.org/obo/CHEBI_29337|http://purl.obolibrary.org/obo/CHEBI_32988 |
| T24346 | 65634-65639 | Chemical | denotes | ester | http://purl.obolibrary.org/obo/CHEBI_35701 |
| T26076 | 65658-65673 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T62302 | 65663-65673 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T97944 | 65712-65723 | Chemical | denotes | carboxamide | http://purl.obolibrary.org/obo/CHEBI_23004|http://purl.obolibrary.org/obo/CHEBI_37622 |
| T99256 | 65814-65828 | Chemical | denotes | etacrynic acid | http://purl.obolibrary.org/obo/CHEBI_4876 |
| T77207 | 65824-65828 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T49733 | 65829-65834 | Chemical | denotes | ester | http://purl.obolibrary.org/obo/CHEBI_35701 |
| T50928 | 65966-65972 | Chemical | denotes | chloro | http://purl.obolibrary.org/obo/CHEBI_47853 |
| T49983 | 66080-66088 | Chemical | denotes | hydrogen | http://purl.obolibrary.org/obo/CHEBI_49637 |
| T25028 | 66153-66158 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T9229 | 66159-66164 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T64536 | 66185-66199 | Chemical | denotes | carbonyl group | http://purl.obolibrary.org/obo/CHEBI_23019 |
| T83383 | 66194-66199 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T57959 | 66280-66286 | Chemical | denotes | sulfur | http://purl.obolibrary.org/obo/CHEBI_26833 |
| T11376 | 66300-66306 | Chemical | denotes | isatin | http://purl.obolibrary.org/obo/CHEBI_27539 |
| T88990 | 66800-66806 | Chemical | denotes | isatin | http://purl.obolibrary.org/obo/CHEBI_27539 |
| T308 | 66868-66877 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T76303 | 66928-66936 | Chemical | denotes | carbonyl | http://purl.obolibrary.org/obo/CHEBI_23019 |
| T73811 | 66951-66957 | Chemical | denotes | isatin | http://purl.obolibrary.org/obo/CHEBI_27539 |
| T84389 | 66987-66989 | Chemical | denotes | NH | http://purl.obolibrary.org/obo/CHEBI_29339|http://purl.obolibrary.org/obo/CHEBI_73424 |
| T93906 | 67343-67354 | Chemical | denotes | carboxamide | http://purl.obolibrary.org/obo/CHEBI_23004|http://purl.obolibrary.org/obo/CHEBI_37622 |
| T3495 | 67545-67556 | Chemical | denotes | carboxamide | http://purl.obolibrary.org/obo/CHEBI_23004|http://purl.obolibrary.org/obo/CHEBI_37622 |
| T34567 | 67594-67606 | Chemical | denotes | sulfonamides | http://purl.obolibrary.org/obo/CHEBI_35358 |
| T8963 | 67789-67799 | Chemical | denotes | pyrazolone | http://purl.obolibrary.org/obo/CHEBI_83328 |
| T52199 | 67804-67812 | Chemical | denotes | pyrazole | http://purl.obolibrary.org/obo/CHEBI_14973|http://purl.obolibrary.org/obo/CHEBI_17241 |
| T97302 | 67851-67866 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T83876 | 67856-67866 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T5399 | 67978-67988 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T15320 | 68163-68174 | Chemical | denotes | benzylidene | http://purl.obolibrary.org/obo/CHEBI_29857 |
| T78951 | 68188-68198 | Chemical | denotes | pyrazolone | http://purl.obolibrary.org/obo/CHEBI_83328 |
| T73608 | 68217-68225 | Chemical | denotes | electron | http://purl.obolibrary.org/obo/CHEBI_10545 |
| T55153 | 68359-68365 | Chemical | denotes | phenyl | http://purl.obolibrary.org/obo/CHEBI_30396 |
| T36598 | 68418-68429 | Chemical | denotes | benzylidene | http://purl.obolibrary.org/obo/CHEBI_29857 |
| T28060 | 68444-68446 | Chemical | denotes | S3 | http://purl.obolibrary.org/obo/CHEBI_29388 |
| T330 | 68494-68505 | Chemical | denotes | pyrimidines | http://purl.obolibrary.org/obo/CHEBI_39447 |
| T14027 | 68520-68535 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T68110 | 68525-68535 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T46132 | 68637-68642 | Chemical | denotes | furan | http://purl.obolibrary.org/obo/CHEBI_35559 |
| T10057 | 68652-68662 | Chemical | denotes | pyrazolone | http://purl.obolibrary.org/obo/CHEBI_83328 |
| T72340 | 68712-68727 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T95181 | 68717-68727 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T23116 | 68996-69006 | Chemical | denotes | pyrimidine | http://purl.obolibrary.org/obo/CHEBI_16898 |
| T19786 | 69033-69048 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T97108 | 69038-69048 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T42754 | 69200-69209 | Chemical | denotes | dipeptide | http://purl.obolibrary.org/obo/CHEBI_46761 |
| T30698 | 69386-69396 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T73037 | 69441-69450 | Chemical | denotes | dipeptide | http://purl.obolibrary.org/obo/CHEBI_46761 |
| T42876 | 69477-69492 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T47808 | 69482-69492 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T38592 | 69729-69743 | Chemical | denotes | peptidomimetic | http://purl.obolibrary.org/obo/CHEBI_63175 |
| T67139 | 69744-69754 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T80936 | 69818-69820 | Chemical | denotes | S3 | http://purl.obolibrary.org/obo/CHEBI_29388 |
| T81382 | 70111-70120 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T52596 | 70294-70296 | Chemical | denotes | ID | http://purl.obolibrary.org/obo/CHEBI_141439 |
| T56133 | 70317-70319 | Chemical | denotes | S3 | http://purl.obolibrary.org/obo/CHEBI_29388 |
| T56319 | 70530-70532 | Chemical | denotes | P1 | http://purl.obolibrary.org/obo/CHEBI_60949 |
| T49271 | 70571-70580 | Chemical | denotes | imidazole | http://purl.obolibrary.org/obo/CHEBI_14434|http://purl.obolibrary.org/obo/CHEBI_16069 |
| T32879 | 70686-70688 | Chemical | denotes | P1 | http://purl.obolibrary.org/obo/CHEBI_60949 |
| T49388 | 70720-70730 | Chemical | denotes | pyridazine | http://purl.obolibrary.org/obo/CHEBI_30954 |
| T17367 | 70741-70749 | Chemical | denotes | pyrazine | http://purl.obolibrary.org/obo/CHEBI_30953 |
| T91954 | 70824-70829 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T60925 | 70912-70925 | Chemical | denotes | benzotriazole | http://purl.obolibrary.org/obo/CHEBI_75331 |
| T359 | 71072-71087 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T8758 | 71077-71087 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T361 | 71103-71116 | Chemical | denotes | benzotriazole | http://purl.obolibrary.org/obo/CHEBI_75331 |
| T362 | 71232-71245 | Chemical | denotes | benzotriazole | http://purl.obolibrary.org/obo/CHEBI_75331 |
| T82901 | 71320-71325 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T364 | 71333-71339 | Chemical | denotes | phenyl | http://purl.obolibrary.org/obo/CHEBI_30396 |
| T44892 | 71346-71354 | Chemical | denotes | triazole | http://purl.obolibrary.org/obo/CHEBI_38597 |
| T366 | 71447-71456 | Chemical | denotes | acetamide | http://purl.obolibrary.org/obo/CHEBI_27856 |
| T73169 | 71458-71460 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
| T368 | 71461-71463 | Chemical | denotes | P1 | http://purl.obolibrary.org/obo/CHEBI_60949 |
| T369 | 71485-71494 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T40652 | 71505-71514 | Chemical | denotes | thiophene | http://purl.obolibrary.org/obo/CHEBI_30856 |
| T33623 | 71549-71555 | Chemical | denotes | propyl | http://purl.obolibrary.org/obo/CHEBI_26308 |
| T20512 | 71556-71561 | Chemical | denotes | amide | http://purl.obolibrary.org/obo/CHEBI_29337|http://purl.obolibrary.org/obo/CHEBI_32988 |
| T75590 | 71678-71688 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T56130 | 71848-71863 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T18706 | 71853-71863 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T1326 | 71954-71964 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T64169 | 72050-72063 | Chemical | denotes | amentoflavone | http://purl.obolibrary.org/obo/CHEBI_2631 |
| T59925 | 72124-72133 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T37429 | 72271-72278 | Chemical | denotes | Flavone | http://purl.obolibrary.org/obo/CHEBI_42491 |
| T50088 | 72283-72292 | Chemical | denotes | terpenoid | http://purl.obolibrary.org/obo/CHEBI_26873 |
| T70109 | 72470-72480 | Chemical | denotes | terpenoids | http://purl.obolibrary.org/obo/CHEBI_26873 |
| T15757 | 72557-72567 | Chemical | denotes | ferruginol | http://purl.obolibrary.org/obo/CHEBI_78274 |
| T36758 | 72646-72653 | Chemical | denotes | quinone | http://purl.obolibrary.org/obo/CHEBI_36141 |
| T94996 | 72662-72675 | Chemical | denotes | triterpenoids | http://purl.obolibrary.org/obo/CHEBI_36615 |
| T73008 | 72676-72685 | Chemical | denotes | celastrol | http://purl.obolibrary.org/obo/CHEBI_63959 |
| T79894 | 72738-72746 | Chemical | denotes | methanol | http://purl.obolibrary.org/obo/CHEBI_17790 |
| T67952 | 72917-72924 | Chemical | denotes | quinone | http://purl.obolibrary.org/obo/CHEBI_36141 |
| T30069 | 72933-72938 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T88567 | 73043-73053 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T18606 | 73103-73111 | Chemical | denotes | abietane | http://purl.obolibrary.org/obo/CHEBI_35673 |
| T56627 | 73117-73129 | Chemical | denotes | diterpenoids | http://purl.obolibrary.org/obo/CHEBI_23849 |
| T52241 | 73199-73213 | Chemical | denotes | betulinic acid | http://purl.obolibrary.org/obo/CHEBI_3087 |
| T39477 | 73209-73213 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T42875 | 73330-73340 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T79585 | 73372-73374 | Chemical | denotes | Lu | http://purl.obolibrary.org/obo/CHEBI_33382 |
| T63566 | 73419-73429 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T7874 | 73431-73438 | Chemical | denotes | sulfone | http://purl.obolibrary.org/obo/CHEBI_35850 |
| T71562 | 73728-73743 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T25413 | 73733-73743 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T35111 | 74026-74041 | Chemical | denotes | Mpro inhibitors | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T69746 | 74031-74041 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T12655 | 74090-74092 | Chemical | denotes | VS | http://purl.obolibrary.org/obo/CHEBI_75021 |
| T45180 | 74120-74122 | Chemical | denotes | VS | http://purl.obolibrary.org/obo/CHEBI_75021 |
| T92281 | 74160-74169 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T42633 | 74194-74203 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T57933 | 74420-74429 | Chemical | denotes | serotonin | http://purl.obolibrary.org/obo/CHEBI_28790|http://purl.obolibrary.org/obo/CHEBI_350546 |
| T63607 | 74430-74440 | Chemical | denotes | antagonist | http://purl.obolibrary.org/obo/CHEBI_48706 |
| T67742 | 74441-74451 | Chemical | denotes | cinanserin | http://purl.obolibrary.org/obo/CHEBI_145999 |
| T60928 | 74484-74493 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T76939 | 74736-74746 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T70812 | 74836-74841 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T94747 | 74842-74852 | Chemical | denotes | disulfiram | http://purl.obolibrary.org/obo/CHEBI_4659 |
| T26685 | 74890-74897 | Chemical | denotes | ebselen | http://purl.obolibrary.org/obo/CHEBI_77543 |
| T67085 | 74974-74976 | Chemical | denotes | MS | http://purl.obolibrary.org/obo/CHEBI_73613 |
| T96011 | 74977-74979 | Chemical | denotes | MS | http://purl.obolibrary.org/obo/CHEBI_73613 |
| T78112 | 75008-75015 | Chemical | denotes | ebselen | http://purl.obolibrary.org/obo/CHEBI_77543 |
| T14009 | 75047-75057 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T420 | 75285-75292 | Chemical | denotes | ebselen | http://purl.obolibrary.org/obo/CHEBI_77543 |
| T40554 | 75297-75306 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T66228 | 75346-75355 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T35779 | 75828-75836 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T82062 | 75912-75922 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T21071 | 76135-76143 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T24059 | 76314-76324 | Chemical | denotes | interferon | http://purl.obolibrary.org/obo/CHEBI_52999 |
| T54555 | 76429-76443 | Chemical | denotes | antiviral drug | http://purl.obolibrary.org/obo/CHEBI_36044 |
| T42980 | 76429-76438 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T18720 | 76439-76443 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T6945 | 76463-76471 | Chemical | denotes | cysteine | http://purl.obolibrary.org/obo/CHEBI_15356 |
| T3561 | 76583-76594 | Chemical | denotes | nucleophile | http://purl.obolibrary.org/obo/CHEBI_59740 |
| T22358 | 76620-76624 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T29111 | 76625-76629 | Chemical | denotes | base | http://purl.obolibrary.org/obo/CHEBI_22695 |
| T41910 | 76705-76708 | Chemical | denotes | Cys | http://purl.obolibrary.org/obo/CHEBI_15356|http://purl.obolibrary.org/obo/CHEBI_17561|http://purl.obolibrary.org/obo/CHEBI_29950 |
| T437 | 76709-76711 | Chemical | denotes | SH | http://purl.obolibrary.org/obo/CHEBI_29312|http://purl.obolibrary.org/obo/CHEBI_73651 |
| T21797 | 76796-76806 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T17235 | 76820-76831 | Chemical | denotes | naphthalene | http://purl.obolibrary.org/obo/CHEBI_16482 |
| T55336 | 76846-76860 | Chemical | denotes | lead compounds | http://purl.obolibrary.org/obo/CHEBI_33585 |
| T442 | 77158-77167 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T41674 | 77200-77215 | Chemical | denotes | racemic mixture | http://purl.obolibrary.org/obo/CHEBI_60911 |
| T43552 | 77208-77215 | Chemical | denotes | mixture | http://purl.obolibrary.org/obo/CHEBI_60004 |
| T96618 | 77409-77415 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T72348 | 77422-77434 | Chemical | denotes | amino groups | http://purl.obolibrary.org/obo/CHEBI_51142 |
| T21234 | 77422-77427 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
| T15943 | 77449-77455 | Chemical | denotes | phenyl | http://purl.obolibrary.org/obo/CHEBI_30396 |
| T58369 | 77650-77659 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T22446 | 77742-77752 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T452 | 77762-77773 | Chemical | denotes | naphthalene | http://purl.obolibrary.org/obo/CHEBI_16482 |
| T453 | 77945-77950 | Chemical | denotes | amide | http://purl.obolibrary.org/obo/CHEBI_29337|http://purl.obolibrary.org/obo/CHEBI_32988 |
| T59470 | 77951-77953 | Chemical | denotes | NH | http://purl.obolibrary.org/obo/CHEBI_29339|http://purl.obolibrary.org/obo/CHEBI_73424 |
| T85501 | 77996-78005 | Chemical | denotes | benzamide | http://purl.obolibrary.org/obo/CHEBI_28179 |
| T21639 | 78148-78157 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T23665 | 78224-78229 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T51563 | 78385-78394 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T1863 | 78586-78598 | Chemical | denotes | methyl group | http://purl.obolibrary.org/obo/CHEBI_32875 |
| T25019 | 78586-78592 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_29309 |
| T26688 | 78593-78598 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T68003 | 78692-78698 | Chemical | denotes | methyl | http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309 |
| T37926 | 78699-78709 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T24619 | 79172-79178 | Chemical | denotes | fluoro | http://purl.obolibrary.org/obo/CHEBI_42645 |
| T84377 | 79191-79200 | Chemical | denotes | benzamide | http://purl.obolibrary.org/obo/CHEBI_28179 |
| T85927 | 79469-79478 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T90186 | 79583-79592 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T3146 | 79936-79946 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T97002 | 80084-80094 | Chemical | denotes | thiopurine | http://purl.obolibrary.org/obo/CHEBI_35666 |
| T30860 | 80145-80155 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T25638 | 80216-80234 | Chemical | denotes | thiocarbonyl group | http://purl.obolibrary.org/obo/CHEBI_30256 |
| T11104 | 80229-80234 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T92852 | 80302-80319 | Chemical | denotes | anticancer agents | http://purl.obolibrary.org/obo/CHEBI_35610 |
| T477 | 80459-80468 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T95879 | 80517-80522 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T71817 | 80538-80554 | Chemical | denotes | diarylheptanoids | http://purl.obolibrary.org/obo/CHEBI_78802 |
| T31826 | 80631-80640 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T66600 | 80708-80716 | Chemical | denotes | carbonyl | http://purl.obolibrary.org/obo/CHEBI_23019 |
| T28022 | 80785-80794 | Chemical | denotes | flavonoid | http://purl.obolibrary.org/obo/CHEBI_47916|http://purl.obolibrary.org/obo/CHEBI_72544 |
| T44605 | 80982-80993 | Chemical | denotes | polyphenols | http://purl.obolibrary.org/obo/CHEBI_26195 |
| T3152 | 81218-81228 | Chemical | denotes | Disulfiram | http://purl.obolibrary.org/obo/CHEBI_4659 |
| T19310 | 81286-81295 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T78735 | 81360-81368 | Chemical | denotes | cysteine | http://purl.obolibrary.org/obo/CHEBI_15356 |
| T62775 | 81543-81552 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T53718 | 81917-81921 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T67369 | 81934-81943 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T12231 | 82070-82078 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T84932 | 82549-82559 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T49879 | 82565-82575 | Chemical | denotes | remdesivir | http://purl.obolibrary.org/obo/CHEBI_145994 |
| T77345 | 82602-82611 | Chemical | denotes | ribavirin | http://purl.obolibrary.org/obo/CHEBI_63580 |
| T10447 | 82619-82630 | Chemical | denotes | favipiravir | http://purl.obolibrary.org/obo/CHEBI_134722 |
| T7340 | 82665-82674 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T57667 | 82821-82831 | Chemical | denotes | Nucleoside | http://purl.obolibrary.org/obo/CHEBI_33838 |
| T42555 | 82890-82899 | Chemical | denotes | adenosine | http://purl.obolibrary.org/obo/CHEBI_16335 |
| T67983 | 82901-82910 | Chemical | denotes | guanosine | http://purl.obolibrary.org/obo/CHEBI_16750 |
| T36809 | 82916-82926 | Chemical | denotes | sofosbuvir | http://purl.obolibrary.org/obo/CHEBI_85083 |
| T84185 | 83068-83073 | Chemical | denotes | cyano | http://purl.obolibrary.org/obo/CHEBI_48819 |
| T47673 | 83085-83092 | Chemical | denotes | adenine | http://purl.obolibrary.org/obo/CHEBI_16708 |
| T55785 | 83095-83105 | Chemical | denotes | nucleoside | http://purl.obolibrary.org/obo/CHEBI_33838 |
| T48934 | 83113-83120 | Chemical | denotes | prodrug | http://purl.obolibrary.org/obo/CHEBI_50266 |
| T38198 | 83126-83133 | Chemical | denotes | prodrug | http://purl.obolibrary.org/obo/CHEBI_50266 |
| T36015 | 83204-83208 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T9292 | 83209-83219 | Chemical | denotes | sofosbuvir | http://purl.obolibrary.org/obo/CHEBI_85083 |
| T28752 | 83277-83292 | Chemical | denotes | phosphoramidate | http://purl.obolibrary.org/obo/CHEBI_29920 |
| T18186 | 83376-83388 | Chemical | denotes | triphosphate | http://purl.obolibrary.org/obo/CHEBI_18036 |
| T4985 | 83396-83406 | Chemical | denotes | metabolite | http://purl.obolibrary.org/obo/CHEBI_25212 |
| T75536 | 83418-83430 | Chemical | denotes | triphosphate | http://purl.obolibrary.org/obo/CHEBI_18036 |
| T512 | 83448-83455 | Chemical | denotes | adenine | http://purl.obolibrary.org/obo/CHEBI_16708 |
| T2873 | 83658-83660 | Chemical | denotes | EM | http://purl.obolibrary.org/obo/CHEBI_73507 |
| T514 | 83696-83706 | Chemical | denotes | remdesivir | http://purl.obolibrary.org/obo/CHEBI_145994 |
| T49423 | 84043-84046 | Chemical | denotes | ATP | http://purl.obolibrary.org/obo/CHEBI_15422|http://purl.obolibrary.org/obo/CHEBI_30616 |
| T31141 | 84244-84253 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T518 | 84259-84269 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T519 | 84492-84501 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T19063 | 84525-84535 | Chemical | denotes | remdesivir | http://purl.obolibrary.org/obo/CHEBI_145994 |
| T26868 | 84737-84747 | Chemical | denotes | remdesivir | http://purl.obolibrary.org/obo/CHEBI_145994 |
| T44704 | 84907-84917 | Chemical | denotes | nucleoside | http://purl.obolibrary.org/obo/CHEBI_33838 |
| T523 | 84940-84949 | Chemical | denotes | adenosine | http://purl.obolibrary.org/obo/CHEBI_16335 |
| T43938 | 84964-84968 | Chemical | denotes | base | http://purl.obolibrary.org/obo/CHEBI_22695 |
| T14297 | 84988-84994 | Chemical | denotes | ribose | http://purl.obolibrary.org/obo/CHEBI_33942|http://purl.obolibrary.org/obo/CHEBI_47013 |
| T87614 | 85046-85055 | Chemical | denotes | adenosine | http://purl.obolibrary.org/obo/CHEBI_16335 |
| T40579 | 85446-85458 | Chemical | denotes | a nucleoside | http://purl.obolibrary.org/obo/CHEBI_33838 |
| T51217 | 85504-85513 | Chemical | denotes | guanosine | http://purl.obolibrary.org/obo/CHEBI_16750 |
| T60616 | 85572-85583 | Chemical | denotes | amide group | http://purl.obolibrary.org/obo/CHEBI_52901 |
| T531 | 85572-85577 | Chemical | denotes | amide | http://purl.obolibrary.org/obo/CHEBI_29337|http://purl.obolibrary.org/obo/CHEBI_32988 |
| T533 | 85578-85583 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T48363 | 85687-85691 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T6634 | 85849-85858 | Chemical | denotes | ribavirin | http://purl.obolibrary.org/obo/CHEBI_63580 |
| T77728 | 85962-85976 | Chemical | denotes | antiviral drug | http://purl.obolibrary.org/obo/CHEBI_36044 |
| T9094 | 85962-85971 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T538 | 85972-85976 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T97357 | 86036-86048 | Chemical | denotes | pyrazinamide | http://purl.obolibrary.org/obo/CHEBI_45285 |
| T83092 | 86182-86189 | Chemical | denotes | guanine | http://purl.obolibrary.org/obo/CHEBI_16235 |
| T74794 | 86231-86241 | Chemical | denotes | metabolite | http://purl.obolibrary.org/obo/CHEBI_25212 |
| T45931 | 86243-86254 | Chemical | denotes | favipiravir | http://purl.obolibrary.org/obo/CHEBI_134722 |
| T20357 | 86255-86268 | Chemical | denotes | ribofuranosyl | http://purl.obolibrary.org/obo/CHEBI_26565 |
| T13775 | 86272-86284 | Chemical | denotes | triphosphate | http://purl.obolibrary.org/obo/CHEBI_18036 |
| T99549 | 86620-86627 | Chemical | denotes | prodrug | http://purl.obolibrary.org/obo/CHEBI_50266 |
| T42860 | 86645-86655 | Chemical | denotes | nucleoside | http://purl.obolibrary.org/obo/CHEBI_33838 |
| T44765 | 86817-86827 | Chemical | denotes | remdesivir | http://purl.obolibrary.org/obo/CHEBI_145994 |
| T43256 | 86943-86957 | Chemical | denotes | hydroxyl group | http://purl.obolibrary.org/obo/CHEBI_43176 |
| T79445 | 86943-86951 | Chemical | denotes | hydroxyl | http://purl.obolibrary.org/obo/CHEBI_29191 |
| T18964 | 86952-86957 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T39781 | 86965-86973 | Chemical | denotes | cytidine | http://purl.obolibrary.org/obo/CHEBI_17562 |
| T96012 | 87112-87122 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T10086 | 87455-87460 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T554 | 87719-87724 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T48660 | 87788-87792 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T82363 | 87883-87893 | Chemical | denotes | interferon | http://purl.obolibrary.org/obo/CHEBI_52999 |
| T93842 | 87895-87898 | Chemical | denotes | IFN | http://purl.obolibrary.org/obo/CHEBI_52999 |
| T72172 | 87959-87962 | Chemical | denotes | IFN | http://purl.obolibrary.org/obo/CHEBI_52999 |
| T93598 | 88026-88029 | Chemical | denotes | IFN | http://purl.obolibrary.org/obo/CHEBI_52999 |
| T11265 | 88056-88059 | Chemical | denotes | IFN | http://purl.obolibrary.org/obo/CHEBI_52999 |
| T21484 | 88201-88216 | Chemical | denotes | antiviral drugs | http://purl.obolibrary.org/obo/CHEBI_36044 |
| T39733 | 88201-88210 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T17520 | 88211-88216 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T24513 | 88222-88231 | Chemical | denotes | ribavirin | http://purl.obolibrary.org/obo/CHEBI_63580 |
| T3437 | 88241-88250 | Chemical | denotes | lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
| T52636 | 88251-88260 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
| T46722 | 88325-88330 | Chemical | denotes | label | http://purl.obolibrary.org/obo/CHEBI_35209 |
| T7580 | 88384-88393 | Chemical | denotes | ribavirin | http://purl.obolibrary.org/obo/CHEBI_63580 |
| T49687 | 88414-88423 | Chemical | denotes | lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
| T73417 | 88424-88433 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
| T571 | 88482-88487 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T65386 | 88503-88512 | Chemical | denotes | ribavirin | http://purl.obolibrary.org/obo/CHEBI_63580 |
| T63966 | 88597-88606 | Chemical | denotes | ribavirin | http://purl.obolibrary.org/obo/CHEBI_63580 |
| T59997 | 88687-88696 | Chemical | denotes | ribavirin | http://purl.obolibrary.org/obo/CHEBI_63580 |
| T575 | 88702-88705 | Chemical | denotes | IFN | http://purl.obolibrary.org/obo/CHEBI_52999 |
| T576 | 88803-88806 | Chemical | denotes | IFN | http://purl.obolibrary.org/obo/CHEBI_52999 |
| T577 | 88821-88830 | Chemical | denotes | ribavirin | http://purl.obolibrary.org/obo/CHEBI_63580 |
| T578 | 88953-88957 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T579 | 89047-89050 | Chemical | denotes | IFN | http://purl.obolibrary.org/obo/CHEBI_52999 |
| T580 | 89166-89171 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T581 | 89300-89304 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T582 | 89305-89315 | Chemical | denotes | amiodarone | http://purl.obolibrary.org/obo/CHEBI_2663 |
| T583 | 89404-89408 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T584 | 89490-89502 | Chemical | denotes | Glycyrrhizin | http://purl.obolibrary.org/obo/CHEBI_15939|http://purl.obolibrary.org/obo/CHEBI_29807 |
| T586 | 89626-89638 | Chemical | denotes | nitric oxide | http://purl.obolibrary.org/obo/CHEBI_16480 |
| T587 | 89633-89638 | Chemical | denotes | oxide | http://purl.obolibrary.org/obo/CHEBI_25741|http://purl.obolibrary.org/obo/CHEBI_29356 |
| T589 | 89669-89678 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T590 | 89693-89701 | Chemical | denotes | NO donor | http://purl.obolibrary.org/obo/CHEBI_50566 |
| T591 | 89696-89701 | Chemical | denotes | donor | http://purl.obolibrary.org/obo/CHEBI_17891 |
| T592 | 89705-89712 | Chemical | denotes | nitroso | http://purl.obolibrary.org/obo/CHEBI_35801 |
| T593 | 89857-89873 | Chemical | denotes | antiviral agents | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T594 | 89938-89943 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T595 | 89955-89965 | Chemical | denotes | cinanserin | http://purl.obolibrary.org/obo/CHEBI_145999 |
| T596 | 89986-89995 | Chemical | denotes | serotonin | http://purl.obolibrary.org/obo/CHEBI_28790|http://purl.obolibrary.org/obo/CHEBI_350546 |
| T598 | 89996-90006 | Chemical | denotes | antagonist | http://purl.obolibrary.org/obo/CHEBI_48706 |
| T599 | 90023-90032 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T600 | 90147-90168 | Chemical | denotes | calmodulin antagonist | http://purl.obolibrary.org/obo/CHEBI_130181 |
| T601 | 90158-90168 | Chemical | denotes | antagonist | http://purl.obolibrary.org/obo/CHEBI_48706 |
| T602 | 90169-90182 | Chemical | denotes | calmidazolium | http://purl.obolibrary.org/obo/CHEBI_75400 |
| T603 | 90199-90213 | Chemical | denotes | Mpro inhibitor | http://purl.obolibrary.org/obo/CHEBI_147285 |
| T604 | 90204-90213 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T605 | 90275-90289 | Chemical | denotes | pharmaceutical | http://purl.obolibrary.org/obo/CHEBI_52217 |
| T606 | 90290-90295 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T607 | 90301-90310 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T608 | 90389-90394 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T609 | 90653-90660 | Chemical | denotes | Emetine | http://purl.obolibrary.org/obo/CHEBI_4781 |
| T610 | 90696-90707 | Chemical | denotes | Chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T611 | 90838-90849 | Chemical | denotes | Amodiaquine | http://purl.obolibrary.org/obo/CHEBI_2674 |
| T612 | 90883-90893 | Chemical | denotes | Loperamide | http://purl.obolibrary.org/obo/CHEBI_6532 |
| T613 | 90926-90935 | Chemical | denotes | Lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
| T614 | 90943-90952 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T615 | 90982-90991 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T616 | 91017-91020 | Chemical | denotes | DNA | http://purl.obolibrary.org/obo/CHEBI_16991 |
| T617 | 91032-91041 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T618 | 91054-91063 | Chemical | denotes | Tamoxifen | http://purl.obolibrary.org/obo/CHEBI_41774 |
| T619 | 91083-91092 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T620 | 91137-91146 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T621 | 91174-91180 | Chemical | denotes | Sterol | http://purl.obolibrary.org/obo/CHEBI_15889 |
| T622 | 91192-91201 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T623 | 91228-91234 | Chemical | denotes | Sterol | http://purl.obolibrary.org/obo/CHEBI_15889 |
| T624 | 91246-91255 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T625 | 91265-91275 | Chemical | denotes | Anisomycin | http://purl.obolibrary.org/obo/CHEBI_338412 |
| T626 | 91277-91284 | Chemical | denotes | Protein | http://purl.obolibrary.org/obo/CHEBI_16541 |
| T627 | 91296-91305 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T628 | 91319-91332 | Chemical | denotes | Cycloheximide | http://purl.obolibrary.org/obo/CHEBI_27641 |
| T629 | 91334-91341 | Chemical | denotes | Protein | http://purl.obolibrary.org/obo/CHEBI_16541 |
| T630 | 91353-91362 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T631 | 91376-91393 | Chemical | denotes | Homoharringtonine | http://purl.obolibrary.org/obo/CHEBI_71019 |
| T632 | 91395-91402 | Chemical | denotes | Protein | http://purl.obolibrary.org/obo/CHEBI_16541 |
| T633 | 91414-91423 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T634 | 91434-91445 | Chemical | denotes | Benztropine | http://purl.obolibrary.org/obo/CHEBI_3048 |
| T635 | 91464-91473 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T636 | 91519-91528 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T637 | 91541-91552 | Chemical | denotes | Thiothixene | http://purl.obolibrary.org/obo/CHEBI_9571 |
| T638 | 91571-91580 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T639 | 91593-91607 | Chemical | denotes | Chlorpromazine | http://purl.obolibrary.org/obo/CHEBI_3647 |
| T640 | 91626-91635 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T641 | 91649-91661 | Chemical | denotes | Fluphenazine | http://purl.obolibrary.org/obo/CHEBI_5123 |
| T642 | 91680-91689 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T643 | 91703-91715 | Chemical | denotes | Promethazine | http://purl.obolibrary.org/obo/CHEBI_8461 |
| T644 | 91734-91743 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T645 | 91786-91795 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T646 | 91843-91852 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T647 | 91867-91883 | Chemical | denotes | Thiethylperazine | http://purl.obolibrary.org/obo/CHEBI_9544 |
| T648 | 91902-91911 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T70724 | 91955-91964 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T650 | 91977-91989 | Chemical | denotes | Clomipramine | http://purl.obolibrary.org/obo/CHEBI_47780 |
| T651 | 92008-92017 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T652 | 92058-92067 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T653 | 92109-92118 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T654 | 92482-92489 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T655 | 92501-92511 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T656 | 92512-92525 | Chemical | denotes | cycloheximide | http://purl.obolibrary.org/obo/CHEBI_27641 |
| T657 | 92600-92622 | Chemical | denotes | HIV protease inhibitor | http://purl.obolibrary.org/obo/CHEBI_35660 |
| T658 | 92604-92622 | Chemical | denotes | protease inhibitor | http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258 |
| T660 | 92613-92622 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T661 | 92623-92632 | Chemical | denotes | lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
| T662 | 92698-92717 | Chemical | denotes | antidiarrheal agent | http://purl.obolibrary.org/obo/CHEBI_55323 |
| T663 | 92718-92728 | Chemical | denotes | loperamide | http://purl.obolibrary.org/obo/CHEBI_6532 |
| T664 | 92815-92823 | Chemical | denotes | alkaloid | http://purl.obolibrary.org/obo/CHEBI_22315 |
| T665 | 92855-92862 | Chemical | denotes | emetine | http://purl.obolibrary.org/obo/CHEBI_4781 |
| T666 | 92878-92887 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T667 | 92919-92938 | Chemical | denotes | antiparasitic drugs | http://purl.obolibrary.org/obo/CHEBI_35442 |
| T668 | 92933-92938 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T669 | 92939-92950 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T670 | 92952-92970 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
| T671 | 92976-92986 | Chemical | denotes | mefloquine | http://purl.obolibrary.org/obo/CHEBI_63609 |
| T672 | 93003-93012 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T673 | 93053-93062 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T674 | 93107-93123 | Chemical | denotes | neurotransmitter | http://purl.obolibrary.org/obo/CHEBI_25512 |
| T675 | 93124-93134 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T676 | 93136-93150 | Chemical | denotes | chlorpromazine | http://purl.obolibrary.org/obo/CHEBI_3647 |
| T677 | 93155-93170 | Chemical | denotes | triflupromazine | http://purl.obolibrary.org/obo/CHEBI_9711 |
| T678 | 93217-93240 | Chemical | denotes | DNA synthesis inhibitor | http://purl.obolibrary.org/obo/CHEBI_59517 |
| T679 | 93217-93220 | Chemical | denotes | DNA | http://purl.obolibrary.org/obo/CHEBI_16991 |
| T680 | 93231-93240 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T681 | 93241-93252 | Chemical | denotes | gemcitabine | http://purl.obolibrary.org/obo/CHEBI_175901 |
| T682 | 93366-93374 | Chemical | denotes | estrogen | http://purl.obolibrary.org/obo/CHEBI_50114 |
| T683 | 93386-93396 | Chemical | denotes | antagonist | http://purl.obolibrary.org/obo/CHEBI_48706 |
| T684 | 93499-93517 | Chemical | denotes | pathway inhibitors | http://purl.obolibrary.org/obo/CHEBI_76932 |
| T685 | 93507-93517 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T686 | 93518-93526 | Chemical | denotes | imatinib | http://purl.obolibrary.org/obo/CHEBI_45783 |
| T687 | 93531-93540 | Chemical | denotes | dasatinib | http://purl.obolibrary.org/obo/CHEBI_49375|http://purl.obolibrary.org/obo/CHEBI_70839 |
| T689 | 93722-93733 | Chemical | denotes | Niclosamide | http://purl.obolibrary.org/obo/CHEBI_7553 |
| T690 | 93755-93767 | Chemical | denotes | anthelmintic | http://purl.obolibrary.org/obo/CHEBI_35443 |
| T691 | 93768-93772 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T692 | 93796-93805 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T693 | 93864-93871 | Chemical | denotes | antigen | http://purl.obolibrary.org/obo/CHEBI_59132 |
| T694 | 94162-94168 | Chemical | denotes | lysine | http://purl.obolibrary.org/obo/CHEBI_18019|http://purl.obolibrary.org/obo/CHEBI_25094 |
| T696 | 94291-94302 | Chemical | denotes | Niclosamide | http://purl.obolibrary.org/obo/CHEBI_7553 |
| T697 | 94430-94435 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T698 | 94472-94486 | Chemical | denotes | antiviral drug | http://purl.obolibrary.org/obo/CHEBI_36044 |
| T699 | 94472-94481 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T700 | 94482-94486 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T701 | 94550-94555 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T702 | 94571-94580 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T703 | 94654-94659 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T704 | 94794-94805 | Chemical | denotes | Niclosamide | http://purl.obolibrary.org/obo/CHEBI_7553 |
| T705 | 94828-94837 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T706 | 94980-94991 | Chemical | denotes | Ciclesonide | http://purl.obolibrary.org/obo/CHEBI_31397 |
| T707 | 95032-95036 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T708 | 95062-95071 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T709 | 95129-95137 | Chemical | denotes | cortisol | http://purl.obolibrary.org/obo/CHEBI_17650 |
| T710 | 95270-95284 | Chemical | denotes | antiviral drug | http://purl.obolibrary.org/obo/CHEBI_36044 |
| T711 | 95270-95279 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T712 | 95280-95284 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T713 | 95389-95391 | Chemical | denotes | en | http://purl.obolibrary.org/obo/CHEBI_30347 |
| T714 | 95457-95461 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T715 | 95501-95510 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T716 | 95779-95797 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
| T717 | 95909-95919 | Chemical | denotes | antibiotic | http://purl.obolibrary.org/obo/CHEBI_33281 |
| T718 | 96022-96026 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T719 | 96089-96099 | Chemical | denotes | colchicine | http://purl.obolibrary.org/obo/CHEBI_23359 |
| T720 | 96453-96457 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T721 | 96630-96642 | Chemical | denotes | a nucleoside | http://purl.obolibrary.org/obo/CHEBI_33838 |
| T722 | 96662-96671 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T723 | 96912-96923 | Chemical | denotes | Fenofibrate | http://purl.obolibrary.org/obo/CHEBI_5001 |
| T724 | 96928-96939 | Chemical | denotes | bezafibrate | http://purl.obolibrary.org/obo/CHEBI_47612 |
| T725 | 96991-97002 | Chemical | denotes | Fenofibrate | http://purl.obolibrary.org/obo/CHEBI_5001 |
| T726 | 97014-97019 | Chemical | denotes | lipid | http://purl.obolibrary.org/obo/CHEBI_18059 |
| T727 | 97029-97037 | Chemical | denotes | medicine | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T728 | 97098-97103 | Chemical | denotes | lipid | http://purl.obolibrary.org/obo/CHEBI_18059 |
| T729 | 97124-97146 | Chemical | denotes | HIV‐protease inhibitor | http://purl.obolibrary.org/obo/CHEBI_35660 |
| T730 | 97128-97146 | Chemical | denotes | protease inhibitor | http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258 |
| T732 | 97137-97146 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T733 | 97147-97157 | Chemical | denotes | nelfinavir | http://purl.obolibrary.org/obo/CHEBI_7496 |
| T734 | 97395-97405 | Chemical | denotes | nelfinavir | http://purl.obolibrary.org/obo/CHEBI_7496 |
| T735 | 97482-97487 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T736 | 97527-97529 | Chemical | denotes | SI | http://purl.obolibrary.org/obo/CHEBI_90326 |
| T737 | 97582-97592 | Chemical | denotes | nelfinavir | http://purl.obolibrary.org/obo/CHEBI_7496 |
| T738 | 97646-97650 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T739 | 97690-97694 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T740 | 97743-97748 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T741 | 97792-97802 | Chemical | denotes | amprenavir | http://purl.obolibrary.org/obo/CHEBI_40050 |
| T742 | 97834-97836 | Chemical | denotes | SI | http://purl.obolibrary.org/obo/CHEBI_90326 |
| T743 | 97846-97855 | Chemical | denotes | darunavir | http://purl.obolibrary.org/obo/CHEBI_367163 |
| T744 | 97887-97889 | Chemical | denotes | SI | http://purl.obolibrary.org/obo/CHEBI_90326 |
| T745 | 97903-97912 | Chemical | denotes | indinavir | http://purl.obolibrary.org/obo/CHEBI_44032 |
| T746 | 97944-97946 | Chemical | denotes | SI | http://purl.obolibrary.org/obo/CHEBI_90326 |
| T747 | 98040-98042 | Chemical | denotes | SI | http://purl.obolibrary.org/obo/CHEBI_90326 |
| T748 | 98094-98096 | Chemical | denotes | SI | http://purl.obolibrary.org/obo/CHEBI_90326 |
| T749 | 98106-98116 | Chemical | denotes | saquinavir | http://purl.obolibrary.org/obo/CHEBI_63621 |
| T750 | 98149-98151 | Chemical | denotes | SI | http://purl.obolibrary.org/obo/CHEBI_90326 |
| T751 | 98165-98175 | Chemical | denotes | atazanavir | http://purl.obolibrary.org/obo/CHEBI_37924 |
| T752 | 98206-98208 | Chemical | denotes | SI | http://purl.obolibrary.org/obo/CHEBI_90326 |
| T753 | 98259-98268 | Chemical | denotes | Lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
| T754 | 98433-98435 | Chemical | denotes | SI | http://purl.obolibrary.org/obo/CHEBI_90326 |
| T755 | 98478-98483 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T756 | 98484-98495 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T757 | 98501-98515 | Chemical | denotes | chlorpromazine | http://purl.obolibrary.org/obo/CHEBI_3647 |
| T758 | 98522-98532 | Chemical | denotes | loperamide | http://purl.obolibrary.org/obo/CHEBI_6532 |
| T759 | 98544-98553 | Chemical | denotes | lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
| T760 | 98592-98597 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T761 | 98954-98965 | Chemical | denotes | Chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T762 | 99117-99121 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T763 | 99131-99135 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T764 | 99186-99196 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T765 | 99199-99213 | Chemical | denotes | Chlorpromazine | http://purl.obolibrary.org/obo/CHEBI_3647 |
| T766 | 99291-99302 | Chemical | denotes | neuroleptic | http://purl.obolibrary.org/obo/CHEBI_35476 |
| T767 | 99303-99307 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T1657 | 99651-99661 | Chemical | denotes | Loperamide | http://purl.obolibrary.org/obo/CHEBI_6532 |
| T99257 | 99672-99695 | Chemical | denotes | opioid receptor agonist | http://purl.obolibrary.org/obo/CHEBI_60606 |
| T41352 | 99688-99695 | Chemical | denotes | agonist | http://purl.obolibrary.org/obo/CHEBI_48705 |
| T55983 | 99785-99794 | Chemical | denotes | Lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
| T16768 | 99807-99829 | Chemical | denotes | HIV protease inhibitor | http://purl.obolibrary.org/obo/CHEBI_35660 |
| T68159 | 99811-99829 | Chemical | denotes | protease inhibitor | http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258 |
| T21127 | 99820-99829 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T88002 | 99959-99968 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T9851 | 99986-99995 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T67871 | 100109-100123 | Chemical | denotes | antipsychotics | http://purl.obolibrary.org/obo/CHEBI_35476 |
| T12849 | 100140-100154 | Chemical | denotes | antidepressant | http://purl.obolibrary.org/obo/CHEBI_35469 |
| T13 | 100359-100367 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T63941 | 100368-100372 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T81847 | 100460-100468 | Chemical | denotes | tyrosine | http://purl.obolibrary.org/obo/CHEBI_18186 |
| T1649 | 100672-100681 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T4254 | 101335-101343 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T84567 | 101344-101349 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T61129 | 101448-101457 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T52368 | 101553-101557 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T30319 | 101668-101677 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T52248 | 101801-101811 | Chemical | denotes | antibiotic | http://purl.obolibrary.org/obo/CHEBI_33281 |
| T99529 | 101866-101868 | Chemical | denotes | ES | http://purl.obolibrary.org/obo/CHEBI_73509 |
| T46766 | 101898-101912 | Chemical | denotes | antiviral drug | http://purl.obolibrary.org/obo/CHEBI_36044 |
| T89019 | 101898-101907 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T87514 | 101908-101912 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T22694 | 101984-101998 | Chemical | denotes | antiviral drug | http://purl.obolibrary.org/obo/CHEBI_36044 |
| T28163 | 101984-101993 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T56638 | 101994-101998 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T68788 | 102040-102044 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T80756 | 102141-102145 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T84162 | 102204-102208 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T62812 | 102268-102272 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T84275 | 102312-102321 | Chemical | denotes | Lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
| T99532 | 102322-102331 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
| T94485 | 102391-102400 | Chemical | denotes | Celecoxib | http://purl.obolibrary.org/obo/CHEBI_41423 |
| T63643 | 102419-102424 | Chemical | denotes | NSAID | http://purl.obolibrary.org/obo/CHEBI_35475 |
| T90267 | 102443-102454 | Chemical | denotes | Chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T52784 | 102470-102474 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T20809 | 102557-102561 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T50574 | 102658-102662 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T46751 | 102684-102686 | Chemical | denotes | ES | http://purl.obolibrary.org/obo/CHEBI_73509 |
| T28396 | 102729-102733 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T99112 | 102771-102781 | Chemical | denotes | Colchicine | http://purl.obolibrary.org/obo/CHEBI_27882 |
| T97639 | 102799-102821 | Chemical | denotes | anti‐inflammatory drug | http://purl.obolibrary.org/obo/CHEBI_35472 |
| T76961 | 102817-102821 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T46010 | 102855-102857 | Chemical | denotes | ES | http://purl.obolibrary.org/obo/CHEBI_73509 |
| T46946 | 102920-102942 | Chemical | denotes | anti‐inflammatory drug | http://purl.obolibrary.org/obo/CHEBI_35472 |
| T69677 | 102938-102942 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T22203 | 103029-103051 | Chemical | denotes | anti‐inflammatory drug | http://purl.obolibrary.org/obo/CHEBI_35472 |
| T77916 | 103047-103051 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T58884 | 103121-103125 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T70065 | 103167-103171 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T97662 | 103232-103246 | Chemical | denotes | Angiotensin II | http://purl.obolibrary.org/obo/CHEBI_2719 |
| T36232 | 103244-103246 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T60201 | 103256-103266 | Chemical | denotes | antagonist | http://purl.obolibrary.org/obo/CHEBI_48706 |
| T64176 | 103313-103322 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T11638 | 103389-103393 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T41579 | 103445-103454 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T93462 | 103530-103539 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T55784 | 103937-103947 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T28876 | 104284-104294 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T17256 | 104408-104418 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T70556 | 104709-104719 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T19135 | 104731-104739 | Chemical | denotes | peptides | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T9484 | 104759-104767 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T70157 | 104856-104864 | Chemical | denotes | peptides | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T35716 | 104966-104976 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T72013 | 105151-105158 | Chemical | denotes | glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167 |
| T45533 | 105169-105176 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T50498 | 105181-105184 | Chemical | denotes | GRP | http://purl.obolibrary.org/obo/CHEBI_144473|http://purl.obolibrary.org/obo/CHEBI_80328 |
| T38457 | 105413-105416 | Chemical | denotes | GRP | http://purl.obolibrary.org/obo/CHEBI_144473|http://purl.obolibrary.org/obo/CHEBI_80328 |
| T61048 | 105572-105575 | Chemical | denotes | GRP | http://purl.obolibrary.org/obo/CHEBI_144473|http://purl.obolibrary.org/obo/CHEBI_80328 |
| T84346 | 105682-105691 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T93444 | 106049-106065 | Chemical | denotes | antiviral agents | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T78395 | 106130-106135 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T73974 | 106276-106281 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T87781 | 106485-106490 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T79642 | 106584-106599 | Chemical | denotes | antiviral drugs | http://purl.obolibrary.org/obo/CHEBI_36044 |
| T585 | 106584-106593 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T58765 | 106594-106599 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T58934 | 106610-106617 | Chemical | denotes | hydroxy | http://purl.obolibrary.org/obo/CHEBI_43176 |
| T10172 | 106618-106629 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T88397 | 106631-106642 | Chemical | denotes | favipiravir | http://purl.obolibrary.org/obo/CHEBI_134722 |
| T93300 | 106644-106653 | Chemical | denotes | ribavirin | http://purl.obolibrary.org/obo/CHEBI_63580 |
| T51965 | 106658-106668 | Chemical | denotes | umifenovir | http://purl.obolibrary.org/obo/CHEBI_134730 |
| T90880 | 106875-106879 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T20459 | 106885-106889 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T99263 | 107267-107283 | Chemical | denotes | antihypertensive | http://purl.obolibrary.org/obo/CHEBI_35674 |
| T91249 | 107549-107565 | Chemical | denotes | antihypertensive | http://purl.obolibrary.org/obo/CHEBI_35674 |
| T4923 | 108655-108657 | Chemical | denotes | TP | http://purl.obolibrary.org/obo/CHEBI_73662 |
| T20134 | 108664-108666 | Chemical | denotes | MM | http://purl.obolibrary.org/obo/CHEBI_53458|http://purl.obolibrary.org/obo/CHEBI_74707 |
| T30576 | 108695-108697 | Chemical | denotes | TP | http://purl.obolibrary.org/obo/CHEBI_73662 |
| T20456 | 109679-109689 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T20923 | 109724-109731 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T35124 | 109799-109804 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T6464 | 110088-110096 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T91474 | 110097-110104 | Chemical | denotes | ligands | http://purl.obolibrary.org/obo/CHEBI_52214 |
| T34780 | 110111-110118 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T91595 | 110233-110247 | Chemical | denotes | pharmaceutical | http://purl.obolibrary.org/obo/CHEBI_52217 |
| T14002 | 110811-110820 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T48280 | 110964-110972 | Chemical | denotes | medicine | http://purl.obolibrary.org/obo/CHEBI_23888 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 104014-104018 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | RdRP |
| T2 | 104529-104545 | http://purl.obolibrary.org/obo/GO_0019058 | denotes | viral life cycle |
| T3 | 104668-104683 | http://purl.obolibrary.org/obo/GO_0061025 | denotes | membrane fusion |
| T4 | 105740-105757 | http://purl.obolibrary.org/obo/GO_0019079 | denotes | viral replication |
| T5 | 105740-105757 | http://purl.obolibrary.org/obo/GO_0019058 | denotes | viral replication |
| T6 | 108459-108475 | http://purl.obolibrary.org/obo/GO_0019058 | denotes | viral life cycle |
| T48484 | 951-968 | http://purl.obolibrary.org/obo/GO_0019079 | denotes | viral replication |
| T22466 | 951-968 | http://purl.obolibrary.org/obo/GO_0019058 | denotes | viral replication |
| T70589 | 1204-1219 | http://purl.obolibrary.org/obo/GO_0039703 | denotes | RNA replication |
| T82780 | 1925-1929 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | RdRP |
| T11747 | 2981-2993 | http://purl.obolibrary.org/obo/GO_0009405 | denotes | pathogenesis |
| T88399 | 6063-6070 | http://purl.obolibrary.org/obo/GO_0009606 | denotes | tropism |
| T7 | 8330-8343 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | transcriptase |
| T8 | 8330-8343 | http://purl.obolibrary.org/obo/GO_0003899 | denotes | transcriptase |
| T9 | 8402-8415 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
| T10 | 8751-8755 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | RdRP |
| T11 | 9823-9839 | http://purl.obolibrary.org/obo/GO_0019058 | denotes | viral life cycle |
| T12 | 10196-10200 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | RdRP |
| T13 | 13565-13569 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | RdRP |
| T14 | 16567-16582 | http://purl.obolibrary.org/obo/GO_0061025 | denotes | membrane fusion |
| T15 | 19064-19091 | http://purl.obolibrary.org/obo/GO_0046718 | denotes | viral entry into host cells |
| T16 | 19070-19085 | http://purl.obolibrary.org/obo/GO_0044409 | denotes | entry into host |
| T17 | 19132-19148 | http://purl.obolibrary.org/obo/GO_0033673 | denotes | kinase inhibitor |
| T18 | 20000-20009 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | virulence |
| T19 | 20000-20009 | http://purl.obolibrary.org/obo/GO_0009405 | denotes | virulence |
| T20 | 20180-20206 | http://purl.obolibrary.org/obo/GO_0008217 | denotes | blood pressure homeostasis |
| T21 | 20195-20206 | http://purl.obolibrary.org/obo/GO_0042592 | denotes | homeostasis |
| T22 | 20480-20492 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
| T23 | 23094-23116 | http://purl.obolibrary.org/obo/GO_0033578 | denotes | terminal glycosylation |
| T24 | 23103-23116 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
| T25 | 24169-24185 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infections |
| T26 | 26295-26305 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
| T27 | 27079-27090 | http://purl.obolibrary.org/obo/GO_0140253 | denotes | cell fusion |
| T28 | 27079-27090 | http://purl.obolibrary.org/obo/GO_0045026 | denotes | cell fusion |
| T29 | 27079-27090 | http://purl.obolibrary.org/obo/GO_0000768 | denotes | cell fusion |
| T30 | 27079-27090 | http://purl.obolibrary.org/obo/GO_0000747 | denotes | cell fusion |
| T31 | 27345-27356 | http://purl.obolibrary.org/obo/GO_0140253 | denotes | cell fusion |
| T32 | 27345-27356 | http://purl.obolibrary.org/obo/GO_0045026 | denotes | cell fusion |
| T33 | 27345-27356 | http://purl.obolibrary.org/obo/GO_0000768 | denotes | cell fusion |
| T34 | 27345-27356 | http://purl.obolibrary.org/obo/GO_0000747 | denotes | cell fusion |
| T35 | 29185-29198 | http://purl.obolibrary.org/obo/GO_0045851 | denotes | Acidification |
| T36 | 29276-29286 | http://purl.obolibrary.org/obo/GO_0004175 | denotes | proteinase |
| T37 | 29529-29544 | http://purl.obolibrary.org/obo/GO_0061025 | denotes | Membrane fusion |
| T38 | 29803-29818 | http://purl.obolibrary.org/obo/GO_0061025 | denotes | membrane fusion |
| T39 | 30003-30019 | http://purl.obolibrary.org/obo/GO_0019058 | denotes | viral life cycle |
| T40 | 30146-30161 | http://purl.obolibrary.org/obo/GO_0061025 | denotes | membrane fusion |
| T41 | 30976-30987 | http://purl.obolibrary.org/obo/GO_0140253 | denotes | cell fusion |
| T42 | 30976-30987 | http://purl.obolibrary.org/obo/GO_0045026 | denotes | cell fusion |
| T43 | 30976-30987 | http://purl.obolibrary.org/obo/GO_0000768 | denotes | cell fusion |
| T44 | 30976-30987 | http://purl.obolibrary.org/obo/GO_0000747 | denotes | cell fusion |
| T45 | 34033-34043 | http://purl.obolibrary.org/obo/GO_0004175 | denotes | proteinase |
| T46 | 34422-34428 | http://purl.obolibrary.org/obo/GO_0098739 | denotes | uptake |
| T47 | 34422-34428 | http://purl.obolibrary.org/obo/GO_0098657 | denotes | uptake |
| T48 | 35015-35030 | http://purl.obolibrary.org/obo/GO_0061025 | denotes | membrane fusion |
| T49 | 35418-35427 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | formation |
| T50 | 35769-35786 | http://purl.obolibrary.org/obo/GO_0019079 | denotes | viral replication |
| T51 | 35769-35786 | http://purl.obolibrary.org/obo/GO_0019058 | denotes | viral replication |
| T52 | 35791-35804 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
| T53 | 36053-36057 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | RdRP |
| T54 | 36175-36191 | http://purl.obolibrary.org/obo/GO_0019058 | denotes | viral life cycle |
| T55 | 36720-36731 | http://purl.obolibrary.org/obo/GO_0006508 | denotes | proteolysis |
| T56 | 37677-37686 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
| T57 | 44677-44686 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | formation |
| T58 | 46768-46777 | http://purl.obolibrary.org/obo/GO_0046903 | denotes | secretion |
| T59 | 47853-47862 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | formation |
| T60 | 51047-51056 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | formation |
| T61 | 55495-55526 | http://purl.obolibrary.org/obo/GO_1903901 | denotes | inhibited the viral replication |
| T62 | 55509-55526 | http://purl.obolibrary.org/obo/GO_0019079 | denotes | viral replication |
| T63 | 55509-55526 | http://purl.obolibrary.org/obo/GO_0019058 | denotes | viral replication |
| T64 | 55904-55911 | http://purl.obolibrary.org/obo/GO_0009606 | denotes | tropism |
| T65 | 58170-58179 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | formation |
| T66 | 75243-75264 | http://purl.obolibrary.org/obo/GO_0001171 | denotes | reverse transcription |
| T67 | 75251-75264 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
| T68 | 76033-76050 | http://purl.obolibrary.org/obo/GO_0019079 | denotes | viral replication |
| T69 | 76033-76050 | http://purl.obolibrary.org/obo/GO_0019058 | denotes | viral replication |
| T70 | 76214-76231 | http://purl.obolibrary.org/obo/GO_0019079 | denotes | viral replication |
| T71 | 76214-76231 | http://purl.obolibrary.org/obo/GO_0019058 | denotes | viral replication |
| T72 | 76276-76292 | http://purl.obolibrary.org/obo/GO_0016579 | denotes | deubiquitinating |
| T73 | 76381-76403 | http://purl.obolibrary.org/obo/GO_0045087 | denotes | innate immune response |
| T74 | 76388-76403 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune response |
| T75 | 79847-79877 | http://purl.obolibrary.org/obo/GO_0004843 | denotes | ubiquitin C‐terminal hydrolase |
| T76 | 81457-81461 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | RdRP |
| T77 | 81666-81670 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | RdRP |
| T78 | 81734-81743 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
| T79 | 81815-81832 | http://purl.obolibrary.org/obo/GO_0019058 | denotes | viral life cycles |
| T80 | 81993-81997 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | RdRP |
| T81 | 82106-82119 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
| T82 | 82527-82531 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | RdRP |
| T83 | 82884-82888 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | RdRP |
| T84 | 82957-82961 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | RdRP |
| T85 | 83359-83368 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | formation |
| T86 | 83465-83469 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | RdRP |
| T87 | 83505-83518 | http://purl.obolibrary.org/obo/GO_0032774 | denotes | RNA synthesis |
| T88 | 83509-83518 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
| T89 | 83686-83690 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | RdRP |
| T90 | 84254-84258 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | RdRP |
| T91 | 84723-84735 | http://purl.obolibrary.org/obo/GO_0009405 | denotes | pathogenesis |
| T92 | 85059-85063 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | RdRP |
| T93 | 85740-85756 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infections |
| T94 | 86155-86159 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | RdRP |
| T95 | 86335-86339 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | RdRP |
| T96 | 86921-86925 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | RdRP |
| T97 | 87107-87111 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | RdRP |
| T98 | 87936-87953 | http://purl.obolibrary.org/obo/GO_0019079 | denotes | viral replication |
| T99 | 87936-87953 | http://purl.obolibrary.org/obo/GO_0019058 | denotes | viral replication |
| T100 | 88555-88572 | http://purl.obolibrary.org/obo/GO_0019079 | denotes | viral replication |
| T101 | 88555-88572 | http://purl.obolibrary.org/obo/GO_0019058 | denotes | viral replication |
| T102 | 89503-89530 | http://purl.obolibrary.org/obo/GO_1903901 | denotes | inhibited viral replication |
| T103 | 89513-89530 | http://purl.obolibrary.org/obo/GO_0019079 | denotes | viral replication |
| T104 | 89513-89530 | http://purl.obolibrary.org/obo/GO_0019058 | denotes | viral replication |
| T105 | 91017-91031 | http://purl.obolibrary.org/obo/GO_0006259 | denotes | DNA metabolism |
| T106 | 91021-91031 | http://purl.obolibrary.org/obo/GO_0008152 | denotes | metabolism |
| T107 | 91174-91191 | http://purl.obolibrary.org/obo/GO_0016125 | denotes | Sterol metabolism |
| T108 | 91181-91191 | http://purl.obolibrary.org/obo/GO_0008152 | denotes | metabolism |
| T109 | 91228-91245 | http://purl.obolibrary.org/obo/GO_0016125 | denotes | Sterol metabolism |
| T110 | 91235-91245 | http://purl.obolibrary.org/obo/GO_0008152 | denotes | metabolism |
| T111 | 91277-91295 | http://purl.obolibrary.org/obo/GO_0016485 | denotes | Protein‐processing |
| T112 | 91334-91352 | http://purl.obolibrary.org/obo/GO_0016485 | denotes | Protein‐processing |
| T113 | 91395-91413 | http://purl.obolibrary.org/obo/GO_0016485 | denotes | Protein‐processing |
| T114 | 92048-92057 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
| T115 | 92099-92108 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
| T116 | 92482-92500 | http://purl.obolibrary.org/obo/GO_0016485 | denotes | protein‐processing |
| T117 | 93217-93230 | http://purl.obolibrary.org/obo/GO_0071897 | denotes | DNA synthesis |
| T118 | 93221-93230 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
| T119 | 93489-93506 | http://purl.obolibrary.org/obo/GO_0007165 | denotes | signaling pathway |
| T120 | 93489-93498 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
| T121 | 93641-93656 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infection |
| T122 | 93872-93881 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
| T123 | 94179-94197 | http://purl.obolibrary.org/obo/GO_0000209 | denotes | polyubiquitination |
| T124 | 94229-94238 | http://purl.obolibrary.org/obo/GO_0016236 | denotes | autophagy |
| T125 | 94229-94238 | http://purl.obolibrary.org/obo/GO_0006914 | denotes | autophagy |
| T126 | 94932-94941 | http://purl.obolibrary.org/obo/GO_0016236 | denotes | autophagy |
| T127 | 94932-94941 | http://purl.obolibrary.org/obo/GO_0006914 | denotes | autophagy |
| T128 | 96177-96189 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
| T129 | 96632-96652 | http://purl.obolibrary.org/obo/GO_0015858 | denotes | nucleoside transport |
| T130 | 96643-96652 | http://purl.obolibrary.org/obo/GO_0006810 | denotes | transport |
| T131 | 96697-96706 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | formation |
| T132 | 99001-99018 | http://purl.obolibrary.org/obo/GO_0019079 | denotes | viral replication |
| T133 | 99001-99018 | http://purl.obolibrary.org/obo/GO_0019058 | denotes | viral replication |
| T134 | 99366-99395 | http://purl.obolibrary.org/obo/GO_0072583 | denotes | clathrin‐mediated endocytosis |
| T135 | 99384-99395 | http://purl.obolibrary.org/obo/GO_0006897 | denotes | endocytosis |
| T136 | 99404-99433 | http://purl.obolibrary.org/obo/GO_0072583 | denotes | clathrin‐mediated endocytosis |
| T137 | 99422-99433 | http://purl.obolibrary.org/obo/GO_0006897 | denotes | endocytosis |
| T138 | 99456-99486 | http://purl.obolibrary.org/obo/GO_0046718 | denotes | viral entry into the host cell |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 1397-1417 | Phenotype | denotes | respiratory distress | http://purl.obolibrary.org/obo/HP_0002098 |
| T2 | 1731-1740 | Phenotype | denotes | hepatitis | http://purl.obolibrary.org/obo/HP_0012115 |
| T3 | 2742-2764 | Phenotype | denotes | respiratory infections | http://purl.obolibrary.org/obo/HP_0011947 |
| T4 | 4112-4121 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T5 | 10655-10676 | Phenotype | denotes | respiratory illnesses | http://purl.obolibrary.org/obo/HP_0002086 |
| T6 | 17056-17072 | Phenotype | denotes | immunodeficiency | http://purl.obolibrary.org/obo/HP_0002721 |
| T7 | 17087-17103 | Phenotype | denotes | immunodeficiency | http://purl.obolibrary.org/obo/HP_0002721 |
| T8 | 20529-20549 | Phenotype | denotes | respiratory distress | http://purl.obolibrary.org/obo/HP_0002098 |
| T9 | 21429-21452 | Phenotype | denotes | cardiovascular diseases | http://purl.obolibrary.org/obo/HP_0001626 |
| T10 | 25588-25610 | Phenotype | denotes | ventricular arrhythmia | http://purl.obolibrary.org/obo/HP_0004308 |
| T11 | 25881-25900 | Phenotype | denotes | autoimmune diseases | http://purl.obolibrary.org/obo/HP_0002960 |
| T12 | 28163-28182 | Phenotype | denotes | high blood pressure | http://purl.obolibrary.org/obo/HP_0000822 |
| T13 | 28795-28808 | Phenotype | denotes | lung diseases | http://purl.obolibrary.org/obo/HP_0002088 |
| T14 | 30499-30508 | Phenotype | denotes | hepatitis | http://purl.obolibrary.org/obo/HP_0012115 |
| T15 | 30529-30539 | Phenotype | denotes | bronchitis | http://purl.obolibrary.org/obo/HP_0012387 |
| T16 | 30564-30573 | Phenotype | denotes | hepatitis | http://purl.obolibrary.org/obo/HP_0012115 |
| T17 | 42966-42976 | Phenotype | denotes | bronchitis | http://purl.obolibrary.org/obo/HP_0012387 |
| T18 | 50059-50070 | Phenotype | denotes | peritonitis | http://purl.obolibrary.org/obo/HP_0002586 |
| T19 | 62966-62982 | Phenotype | denotes | immunodeficiency | http://purl.obolibrary.org/obo/HP_0002721 |
| T20 | 83192-83201 | Phenotype | denotes | hepatitis | http://purl.obolibrary.org/obo/HP_0012115 |
| T21 | 95163-95169 | Phenotype | denotes | asthma | http://purl.obolibrary.org/obo/HP_0002099 |
| T22 | 95174-95191 | Phenotype | denotes | allergic rhinitis | http://purl.obolibrary.org/obo/HP_0003193 |
| T23 | 96364-96377 | Phenotype | denotes | peptic ulcers | http://purl.obolibrary.org/obo/HP_0004398 |
| T24 | 96382-96413 | Phenotype | denotes | gastroesophageal reflux disease | http://purl.obolibrary.org/obo/HP_0002020 |
| T25 | 96854-96874 | Phenotype | denotes | erectile dysfunction | http://purl.obolibrary.org/obo/HP_0100639 |
| T26 | 96879-96910 | Phenotype | denotes | pulmonary arterial hypertension | http://purl.obolibrary.org/obo/HP_0002092 |
| T27 | 99321-99334 | Phenotype | denotes | schizophrenia | http://purl.obolibrary.org/obo/HP_0100753 |
| T28 | 99704-99712 | Phenotype | denotes | diarrhea | http://purl.obolibrary.org/obo/HP_0002014 |
| T29 | 110861-110874 | Phenotype | denotes | heart failure | http://purl.obolibrary.org/obo/HP_0001635 |
| T30 | 110876-110888 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
| T31 | 110893-110899 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 2 | 24-29 | Species | denotes | human | Tax:9606 |
| 3 | 30-43 | Species | denotes | coronaviruses | Tax:11118 |
| 26 | 1015-1020 | Gene | denotes | spike | Gene:43740568 |
| 27 | 115-128 | Species | denotes | Coronaviruses | Tax:11118 |
| 28 | 130-134 | Species | denotes | CoVs | Tax:11118 |
| 29 | 148-154 | Species | denotes | humans | Tax:9606 |
| 30 | 171-177 | Species | denotes | humans | Tax:9606 |
| 31 | 179-183 | Species | denotes | CoVs | Tax:11118 |
| 32 | 334-349 | Species | denotes | β‐coronaviruses | Tax:694002 |
| 33 | 393-399 | Species | denotes | humans | Tax:9606 |
| 34 | 401-445 | Species | denotes | severe‐acute respiratory syndrome (SARS)‐CoV | Tax:694009 |
| 35 | 483-492 | Species | denotes | MERS)‐CoV | Tax:1335626 |
| 36 | 498-508 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 37 | 510-519 | Species | denotes | 2019‐nCoV | Tax:2697049 |
| 38 | 585-590 | Species | denotes | human | Tax:9606 |
| 39 | 594-599 | Species | denotes | human | Tax:9606 |
| 40 | 733-736 | Species | denotes | CoV | Tax:11118 |
| 41 | 874-882 | Species | denotes | SARS‐CoV | Tax:694009 |
| 42 | 886-894 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 43 | 896-906 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 44 | 194-205 | Species | denotes | respiratory | Tax:12814 |
| 45 | 461-472 | Species | denotes | respiratory | Tax:12814 |
| 46 | 233-254 | Disease | denotes | intestinal infections | MESH:D007239 |
| 47 | 737-747 | Disease | denotes | infections | MESH:D007239 |
| 49 | 1236-1242 | Chemical | denotes | 3CLpro | |
| 51 | 1299-1302 | Gene | denotes | ACE | Gene:1636 |
| 53 | 1317-1326 | Chemical | denotes | adenosine | MESH:D000241 |
| 55 | 1386-1390 | Disease | denotes | ARDS | MESH:D012128 |
| 57 | 1391-1426 | Disease | denotes | acute respiratory distress syndrome | MESH:D012128 |
| 59 | 1699-1710 | Species | denotes | respiratory | Tax:12814 |
| 61 | 1725-1746 | Species | denotes | mouse hepatitis virus | Tax:11138 |
| 63 | 1855-1860 | Chemical | denotes | PLpro | |
| 65 | 1977-1988 | Species | denotes | respiratory | Tax:12814 |
| 67 | 2003-2008 | Gene | denotes | TNF‐α | Gene:7124 |
| 69 | 2046-2067 | Disease | denotes | gastroenteritis virus | MESH:D005759 |
| 71 | 2089-2095 | Chemical | denotes | serine | MESH:D012694 |
| 102 | 2122-2135 | Species | denotes | Coronaviruses | Tax:11118 |
| 103 | 2137-2141 | Species | denotes | CoVs | Tax:11118 |
| 104 | 2150-2156 | Species | denotes | humans | Tax:9606 |
| 105 | 2173-2179 | Species | denotes | humans | Tax:9606 |
| 106 | 2181-2185 | Species | denotes | CoVs | Tax:11118 |
| 107 | 2370-2374 | Species | denotes | CoVs | Tax:11118 |
| 108 | 2397-2410 | Species | denotes | Coronaviridae | Tax:11118 |
| 109 | 2440-2453 | Species | denotes | Coronaviridae | Tax:11118 |
| 110 | 2585-2598 | Species | denotes | coronaviruses | Tax:11118 |
| 111 | 2629-2634 | Species | denotes | human | Tax:9606 |
| 112 | 2635-2639 | Species | denotes | CoVs | Tax:11118 |
| 113 | 2693-2698 | Species | denotes | human | Tax:9606 |
| 114 | 2699-2703 | Species | denotes | CoVs | Tax:11118 |
| 115 | 2723-2731 | Species | denotes | patients | Tax:9606 |
| 116 | 2789-2798 | Species | denotes | HCoV‐229E | Tax:11137 |
| 117 | 2803-2812 | Species | denotes | HCoV‐OC43 | Tax:31631 |
| 118 | 2829-2842 | Species | denotes | coronaviruses | Tax:11118 |
| 119 | 3040-3044 | Species | denotes | CoVs | Tax:11118 |
| 120 | 3058-3073 | Species | denotes | β‐coronaviruses | Tax:694002 |
| 121 | 3122-3128 | Species | denotes | humans | Tax:9606 |
| 122 | 3166-3175 | Species | denotes | HCoV‐NL63 | Tax:277944 |
| 123 | 3177-3221 | Species | denotes | severe‐acute respiratory syndrome (SARS)‐CoV | Tax:694009 |
| 124 | 3259-3268 | Species | denotes | MERS)‐CoV | Tax:1335626 |
| 125 | 3274-3284 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 126 | 3237-3248 | Species | denotes | respiratory | Tax:12814 |
| 127 | 3159-3163 | Species | denotes | HKU1 | Tax:290028 |
| 128 | 2211-2248 | Disease | denotes | respiratory and intestinal infections | MESH:D012141 |
| 129 | 2742-2764 | Disease | denotes | respiratory infections | MESH:D012141 |
| 130 | 2925-2934 | Disease | denotes | infection | MESH:D007239 |
| 131 | 3286-3294 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 137 | 3351-3364 | Species | denotes | Coronaviridae | Tax:11118 |
| 138 | 3442-3447 | Species | denotes | human | Tax:9606 |
| 139 | 3458-3471 | Species | denotes | coronaviruses | Tax:11118 |
| 140 | 3492-3505 | Species | denotes | β‐coronavirus | Tax:694002 |
| 141 | 3520-3530 | Species | denotes | infectious | Tax:11120 |
| 148 | 3718-3724 | Species | denotes | humans | Tax:9606 |
| 149 | 3726-3734 | Species | denotes | SARS‐CoV | Tax:694009 |
| 150 | 3837-3845 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 151 | 3804-3808 | Disease | denotes | died | MESH:D003643 |
| 152 | 3921-3925 | Disease | denotes | died | MESH:D003643 |
| 153 | 3935-3944 | Disease | denotes | mortality | MESH:D003643 |
| 163 | 3975-3990 | Species | denotes | new coronavirus | Tax:2697049 |
| 164 | 4001-4011 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 165 | 4015-4024 | Species | denotes | 2019‐nCoV | Tax:2697049 |
| 166 | 4203-4213 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 167 | 4284-4290 | Species | denotes | people | Tax:9606 |
| 168 | 4559-4564 | Species | denotes | human | Tax:9606 |
| 169 | 4575-4579 | Species | denotes | CoVs | Tax:11118 |
| 170 | 4112-4121 | Disease | denotes | pneumonia | MESH:D011014 |
| 171 | 4254-4262 | Disease | denotes | infected | MESH:D007239 |
| 175 | 4626-4631 | Species | denotes | human | Tax:9606 |
| 176 | 4632-4636 | Species | denotes | CoVs | Tax:11118 |
| 177 | 4607-4616 | Disease | denotes | Infection | MESH:D007239 |
| 192 | 4665-4670 | Species | denotes | Human | Tax:9606 |
| 193 | 4681-4685 | Species | denotes | CoVs | Tax:11118 |
| 194 | 4710-4715 | Species | denotes | β‐CoV | Tax:694002 |
| 195 | 4784-4789 | Species | denotes | human | Tax:9606 |
| 196 | 4790-4794 | Species | denotes | CoVs | Tax:11118 |
| 197 | 4816-4825 | Species | denotes | HCoV‐NL63 | Tax:277944 |
| 198 | 4827-4836 | Species | denotes | HCoV‐229E | Tax:11137 |
| 199 | 4838-4846 | Species | denotes | SARS‐CoV | Tax:694009 |
| 200 | 4850-4860 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 201 | 4866-4874 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 202 | 4919-4928 | Species | denotes | HCoV‐OC43 | Tax:31631 |
| 203 | 4938-4941 | Species | denotes | CoV | Tax:11118 |
| 204 | 4965-4972 | Species | denotes | rodents | Tax:314147 |
| 205 | 4933-4937 | Species | denotes | HKU1 | Tax:290028 |
| 208 | 4983-4987 | Species | denotes | CoVs | Tax:11118 |
| 209 | 5147-5157 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 212 | 5572-5577 | Gene | denotes | spike | Gene:43740568 |
| 213 | 5660-5664 | Species | denotes | CoVs | Tax:11118 |
| 231 | 6169-6200 | Gene | denotes | angiotensin‐converting enzyme 2 | Gene:59272 |
| 232 | 6202-6206 | Gene | denotes | ACE2 | Gene:59272 |
| 233 | 6239-6261 | Gene | denotes | dipeptidyl peptidase‐4 | Gene:1803 |
| 234 | 6263-6267 | Gene | denotes | DPP4 | Gene:1803 |
| 235 | 5783-5786 | Species | denotes | CoV | Tax:11118 |
| 236 | 6072-6076 | Species | denotes | CoVs | Tax:11118 |
| 237 | 6091-6096 | Species | denotes | human | Tax:9606 |
| 238 | 6127-6135 | Species | denotes | SARS‐CoV | Tax:694009 |
| 239 | 6139-6149 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 240 | 6155-6164 | Species | denotes | HCoV‐NL63 | Tax:277944 |
| 241 | 6225-6233 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 242 | 6274-6277 | Species | denotes | CoV | Tax:11118 |
| 243 | 6313-6322 | Species | denotes | HCoV‐OC43 | Tax:31631 |
| 244 | 6287-6303 | Gene | denotes | aminopeptidase N | Gene:290 |
| 245 | 6361-6372 | Chemical | denotes | sialic acid | MESH:D019158 |
| 246 | 5762-5771 | Disease | denotes | infection | MESH:D007239 |
| 247 | 5978-5986 | Disease | denotes | infected | MESH:D007239 |
| 254 | 6426-6439 | Species | denotes | coronaviruses | Tax:11118 |
| 255 | 6454-6464 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 256 | 6578-6588 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 257 | 6590-6637 | Species | denotes | severe acute respiratory syndrome coronavirus 2 | Tax:2697049 |
| 258 | 6407-6416 | Disease | denotes | Infection | MESH:D007239 |
| 259 | 6557-6575 | Disease | denotes | covid-19-infection | MESH:C000657245 |
| 280 | 6913-6929 | Gene | denotes | aminopeptidase N | Gene:290 |
| 281 | 6931-6935 | Gene | denotes | CD13 | Gene:290 |
| 282 | 6960-6964 | Gene | denotes | ACE2 | Gene:59272 |
| 283 | 7121-7125 | Gene | denotes | ACE2 | Gene:59272 |
| 284 | 7192-7196 | Gene | denotes | ACE2 | Gene:59272 |
| 285 | 7155-7159 | Gene | denotes | DPP4 | Gene:1803 |
| 286 | 6812-6825 | Species | denotes | Coronaviruses | Tax:11118 |
| 287 | 6875-6888 | Species | denotes | Coronaviruses | Tax:11118 |
| 288 | 6890-6899 | Species | denotes | HCoV‐229E | Tax:11137 |
| 289 | 6907-6912 | Species | denotes | Human | Tax:9606 |
| 290 | 6943-6952 | Species | denotes | HCoV‐NL63 | Tax:277944 |
| 291 | 6984-6999 | Species | denotes | β‐Coronaviruses | Tax:694002 |
| 292 | 7001-7010 | Species | denotes | HCoV‐OC43 | Tax:31631 |
| 293 | 7046-7052 | Species | denotes | Cattle | Tax:9913 |
| 294 | 7053-7062 | Species | denotes | HCoV‐HKU1 | Tax:290028 |
| 295 | 7098-7102 | Species | denotes | Mice | Tax:10090 |
| 296 | 7103-7111 | Species | denotes | SARS‐CoV | Tax:694009 |
| 297 | 7139-7147 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 298 | 7167-7173 | Species | denotes | camels | Tax:9837 |
| 299 | 7174-7184 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 301 | 7249-7259 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 303 | 7441-7449 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 307 | 7676-7681 | Gene | denotes | spike | Gene:43740568 |
| 308 | 7885-7916 | Gene | denotes | transmembrane serine protease 2 | Gene:7113 |
| 309 | 7918-7925 | Gene | denotes | TMPRSS2 | Gene:7113 |
| 312 | 8271-8275 | Gene | denotes | pp1a | Gene:5499 |
| 313 | 8600-8604 | Gene | denotes | Mpro | Gene:8673700 |
| 315 | 8751-8755 | Gene | denotes | RdRP | Gene:43740578 |
| 324 | 9580-9589 | Gene | denotes | cytokines | |
| 325 | 9594-9629 | Gene | denotes | chemokines like interleukin 1 (IL‐1 | Gene:3552 |
| 326 | 9632-9636 | Gene | denotes | IL‐6 | Gene:3569 |
| 327 | 9638-9642 | Gene | denotes | IL‐8 | Gene:3576 |
| 328 | 9644-9649 | Gene | denotes | IL‐21 | Gene:59067 |
| 329 | 9651-9656 | Gene | denotes | TNF‐β | Gene:7124 |
| 330 | 9662-9667 | Gene | denotes | MCP‐1 | Gene:6347 |
| 331 | 9432-9440 | Disease | denotes | infected | MESH:D007239 |
| 342 | 10180-10184 | Gene | denotes | Mpro | Gene:8673700 |
| 343 | 10196-10200 | Gene | denotes | RdRP | Gene:43740578 |
| 344 | 9898-9901 | Species | denotes | CoV | Tax:11118 |
| 345 | 9929-9939 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 346 | 9940-9945 | Species | denotes | human | Tax:9606 |
| 347 | 9995-10005 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 348 | 10125-10136 | Species | denotes | coronavirus | Tax:11118 |
| 349 | 10337-10345 | Species | denotes | SARS‐CoV | Tax:694009 |
| 350 | 10359-10367 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 351 | 10655-10676 | Disease | denotes | respiratory illnesses | MESH:D012140 |
| 372 | 10716-10721 | Gene | denotes | spike | Gene:43740568 |
| 373 | 11327-11331 | Gene | denotes | ACE2 | Gene:59272 |
| 374 | 11460-11464 | Gene | denotes | ACE2 | Gene:59272 |
| 375 | 11569-11573 | Gene | denotes | ACE2 | Gene:59272 |
| 376 | 11589-11593 | Gene | denotes | ACE2 | Gene:59272 |
| 377 | 11259-11260 | Gene | denotes | S | Gene:43740568 |
| 378 | 11220-11221 | Gene | denotes | S | Gene:43740568 |
| 379 | 11179-11180 | Gene | denotes | S | Gene:43740568 |
| 380 | 11042-11043 | Gene | denotes | S | Gene:43740568 |
| 381 | 11252-11257 | Gene | denotes | spike | Gene:43740568 |
| 382 | 10897-10907 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 383 | 10972-10980 | Species | denotes | SARS‐CoV | Tax:694009 |
| 384 | 11011-11014 | Species | denotes | CoV | Tax:11118 |
| 385 | 11031-11041 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 386 | 11138-11142 | Species | denotes | CoVs | Tax:11118 |
| 387 | 11168-11178 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 388 | 11241-11251 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 389 | 11558-11568 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 390 | 11578-11586 | Species | denotes | SARS‐CoV | Tax:694009 |
| 391 | 11499-11508 | Disease | denotes | infection | MESH:D007239 |
| 406 | 11894-11895 | Gene | denotes | S | Gene:43740568 |
| 407 | 11840-11841 | Gene | denotes | S | Gene:43740568 |
| 408 | 11745-11746 | Gene | denotes | S | Gene:43740568 |
| 409 | 11676-11677 | Gene | denotes | S | Gene:43740568 |
| 410 | 11665-11675 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 411 | 11682-11690 | Species | denotes | SARS‐CoV | Tax:694009 |
| 412 | 11734-11744 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 413 | 11755-11763 | Species | denotes | SARS‐CoV | Tax:694009 |
| 414 | 11829-11839 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 415 | 11850-11858 | Species | denotes | SARS‐CoV | Tax:694009 |
| 416 | 11883-11893 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 417 | 11904-11912 | Species | denotes | SARS‐CoV | Tax:694009 |
| 418 | 11962-11972 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 419 | 11974-12021 | Species | denotes | severe acute respiratory syndrome coronavirus 2 | Tax:2697049 |
| 430 | 12468-12472 | Gene | denotes | ACE2 | Gene:59272 |
| 431 | 12570-12574 | Gene | denotes | ACE2 | Gene:59272 |
| 432 | 12165-12175 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 433 | 12276-12280 | Species | denotes | CoVs | Tax:11118 |
| 434 | 12327-12337 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 435 | 12398-12413 | Species | denotes | bat coronavirus | Tax:1508220 |
| 436 | 12436-12444 | Species | denotes | SARS‐CoV | Tax:694009 |
| 437 | 12448-12458 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 438 | 12564-12569 | Species | denotes | human | Tax:9606 |
| 439 | 12595-12605 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 455 | 12723-12728 | Gene | denotes | spike | Gene:43740568 |
| 456 | 12803-12808 | Gene | denotes | spike | Gene:43740568 |
| 457 | 12930-12934 | Gene | denotes | ACE2 | Gene:59272 |
| 458 | 13175-13179 | Gene | denotes | ACE2 | Gene:59272 |
| 459 | 13291-13295 | Gene | denotes | ACE2 | Gene:59272 |
| 460 | 13409-13413 | Gene | denotes | ACE2 | Gene:59272 |
| 461 | 13285-13290 | Gene | denotes | spike | Gene:43740568 |
| 462 | 12745-12753 | Species | denotes | SARS‐CoV | Tax:694009 |
| 463 | 12770-12780 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 464 | 12866-12874 | Species | denotes | SARS‐CoV | Tax:694009 |
| 465 | 12973-12983 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 466 | 13014-13019 | Species | denotes | human | Tax:9606 |
| 467 | 13274-13282 | Species | denotes | SARS‐CoV | Tax:694009 |
| 468 | 13453-13463 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 469 | 13360-13368 | Chemical | denotes | hydrogen | MESH:D006859 |
| 478 | 13565-13569 | Gene | denotes | RdRP | Gene:43740578 |
| 479 | 13874-13880 | Gene | denotes | SARS‐2 | Gene:54938 |
| 480 | 13579-13583 | Gene | denotes | Mpro | Gene:8673700 |
| 481 | 13613-13623 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 482 | 13628-13636 | Species | denotes | SARS‐CoV | Tax:694009 |
| 483 | 13688-13698 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 484 | 13720-13728 | Species | denotes | SARS‐CoV | Tax:694009 |
| 485 | 13881-13885 | Species | denotes | CoVs | Tax:11118 |
| 499 | 14598-14602 | Gene | denotes | ACE2 | Gene:59272 |
| 500 | 14787-14791 | Gene | denotes | ACE2 | Gene:59272 |
| 501 | 15196-15200 | Gene | denotes | ACE2 | Gene:59272 |
| 502 | 15495-15499 | Gene | denotes | ACE2 | Gene:59272 |
| 503 | 14906-14914 | Species | denotes | SARS‐CoV | Tax:694009 |
| 504 | 15052-15060 | Species | denotes | SARS‐CoV | Tax:694009 |
| 505 | 15246-15254 | Species | denotes | SARS‐CoV | Tax:694009 |
| 506 | 15409-15419 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 507 | 15462-15472 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 508 | 15489-15494 | Species | denotes | human | Tax:9606 |
| 509 | 15133-15140 | Chemical | denotes | glycine | MESH:D005998 |
| 510 | 14674-14680 | Disease | denotes | Hsiang | |
| 511 | 15306-15318 | Disease | denotes | cytotoxicity | MESH:D064420 |
| 522 | 15650-15654 | Gene | denotes | DPP4 | Gene:1803 |
| 523 | 15686-15726 | Gene | denotes | adenosine deaminase‐complexing protein‐2 | Gene:1803 |
| 524 | 15730-15734 | Gene | denotes | CD26 | Gene:1803 |
| 525 | 15822-15826 | Gene | denotes | DPP4 | Gene:1803 |
| 526 | 15982-15986 | Gene | denotes | DPP4 | Gene:1803 |
| 527 | 15597-15602 | Gene | denotes | spike | Gene:43740568 |
| 528 | 15579-15587 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 529 | 15740-15748 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 530 | 15974-15980 | Species | denotes | humans | Tax:9606 |
| 531 | 15949-15959 | Chemical | denotes | dipeptides | MESH:D004151 |
| 541 | 16294-16298 | Gene | denotes | DPP4 | Gene:1803 |
| 542 | 16152-16160 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 543 | 16199-16204 | Species | denotes | yeast | Tax:4932 |
| 544 | 16339-16347 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 545 | 16387-16395 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 546 | 16281-16290 | Disease | denotes | infection | MESH:D007239 |
| 547 | 16430-16443 | Disease | denotes | MERS‐infected | MESH:D018352 |
| 548 | 16310-16315 | CellLine | denotes | Huh‐7 | CVCL:0336 |
| 549 | 16449-16451 | CellLine | denotes | E6 | CVCL:4582 |
| 561 | 17210-17211 | Gene | denotes | S | Gene:43740568 |
| 562 | 16596-16604 | Species | denotes | SARS‐CoV | Tax:694009 |
| 563 | 16982-16993 | Species | denotes | Nipah virus | Tax:121791 |
| 564 | 16995-17007 | Species | denotes | Hendra virus | Tax:63330 |
| 565 | 17009-17020 | Species | denotes | Ebola virus | Tax:1570291 |
| 566 | 17049-17078 | Species | denotes | simian immunodeficiency virus | Tax:11723 |
| 567 | 17080-17109 | Species | denotes | feline immunodeficiency virus | Tax:11673 |
| 568 | 17115-17142 | Species | denotes | respiratory syncytial virus | Tax:12814 |
| 569 | 17184-17192 | Species | denotes | SARS‐CoV | Tax:694009 |
| 570 | 17199-17209 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 571 | 17326-17336 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 576 | 17828-17832 | Gene | denotes | ACE2 | Gene:59272 |
| 577 | 17987-17991 | Gene | denotes | ACE2 | Gene:59272 |
| 578 | 17722-17730 | Species | denotes | SARS‐CoV | Tax:694009 |
| 579 | 17638-17657 | Chemical | denotes | oxazole‐carboxamide | |
| 587 | 18193-18201 | Species | denotes | SARS‐CoV | Tax:694009 |
| 588 | 18674-18678 | Species | denotes | mice | Tax:10090 |
| 589 | 18764-18772 | Species | denotes | SARS‐CoV | Tax:694009 |
| 590 | 18684-18693 | Chemical | denotes | Quercetin | MESH:D011794 |
| 591 | 18320-18332 | Disease | denotes | cytotoxicity | MESH:D064420 |
| 592 | 18479-18487 | Disease | denotes | toxicity | MESH:D064420 |
| 593 | 18247-18249 | CellLine | denotes | E6 | CVCL:4582 |
| 599 | 18859-18878 | Gene | denotes | ADS‐J1 (5; Figure 4 | |
| 600 | 18895-18903 | Species | denotes | SARS‐CoV | Tax:694009 |
| 601 | 19164-19167 | Species | denotes | CoV | Tax:11118 |
| 602 | 19097-19105 | Chemical | denotes | Imatinib | MESH:D000068877 |
| 603 | 19031-19053 | Disease | denotes | SARS‐CoV‐1 S HR region | MESH:C000657245 |
| 617 | 19580-19584 | Gene | denotes | ACE2 | Gene:59272 |
| 618 | 19769-19774 | Gene | denotes | spike | Gene:43740568 |
| 619 | 19776-19777 | Gene | denotes | S | Gene:43740568 |
| 620 | 19924-19928 | Gene | denotes | ACE2 | Gene:59272 |
| 621 | 19905-19906 | Gene | denotes | S | Gene:43740568 |
| 622 | 19373-19383 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 623 | 19420-19428 | Species | denotes | SARS‐CoV | Tax:694009 |
| 624 | 19553-19561 | Species | denotes | SARS‐CoV | Tax:694009 |
| 625 | 19740-19750 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 626 | 19792-19800 | Species | denotes | SARS‐CoV | Tax:694009 |
| 627 | 19868-19876 | Species | denotes | SARS‐CoV | Tax:694009 |
| 628 | 19894-19904 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 629 | 19542-19551 | Disease | denotes | infection | MESH:D007239 |
| 649 | 20039-20042 | Gene | denotes | ACE | Gene:1636 |
| 650 | 20213-20217 | Gene | denotes | ACE1 | Gene:1636 |
| 651 | 20222-20226 | Gene | denotes | ACE2 | Gene:59272 |
| 652 | 20279-20283 | Gene | denotes | ACE1 | Gene:1636 |
| 653 | 20661-20664 | Gene | denotes | ACE | Gene:1636 |
| 654 | 20586-20594 | Species | denotes | patients | Tax:9606 |
| 655 | 20609-20617 | Species | denotes | SARS‐CoV | Tax:694009 |
| 656 | 20623-20633 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 657 | 20152-20155 | Chemical | denotes | Ang | |
| 658 | 20234-20246 | Chemical | denotes | Ang peptides | |
| 659 | 20377-20386 | Chemical | denotes | dipeptide | MESH:D004151 |
| 660 | 20387-20390 | Chemical | denotes | His | MESH:D006639 |
| 661 | 20391-20394 | Chemical | denotes | Leu | MESH:D007930 |
| 662 | 20480-20492 | Disease | denotes | inflammation | MESH:D007249 |
| 663 | 20498-20506 | Disease | denotes | fibrosis | MESH:D005355 |
| 664 | 20523-20558 | Disease | denotes | acute respiratory distress syndrome | MESH:D012128 |
| 665 | 20560-20564 | Disease | denotes | ARDS | MESH:D012128 |
| 666 | 20570-20582 | Disease | denotes | lung failure | MESH:D012131 |
| 667 | 20595-20603 | Disease | denotes | infected | MESH:D007239 |
| 673 | 20820-20830 | Gene | denotes | ACE1 and 2 | Gene:1636 |
| 674 | 20956-20966 | Gene | denotes | ACE1 and 2 | Gene:1636 |
| 675 | 20970-20987 | Gene | denotes | renin‐angiotensin | |
| 676 | 20996-20999 | Gene | denotes | ACE | Gene:1636 |
| 677 | 21001-21030 | Gene | denotes | angiotensin‐converting enzyme | Gene:1636 |
| 686 | 21086-21090 | Gene | denotes | ACE2 | Gene:59272 |
| 687 | 21201-21205 | Gene | denotes | ACE1 | Gene:1636 |
| 688 | 21311-21319 | Gene | denotes | Ang (1–9 | Gene:7108 |
| 689 | 21369-21373 | Gene | denotes | ACE2 | Gene:59272 |
| 690 | 21325-21333 | Gene | denotes | Ang (1–7 | Gene:7108 |
| 691 | 21251-21254 | Chemical | denotes | Leu | MESH:D007930 |
| 692 | 21258-21261 | Chemical | denotes | Phe | MESH:D010649 |
| 693 | 21429-21452 | Disease | denotes | cardiovascular diseases | MESH:D002318 |
| 697 | 21529-21533 | Gene | denotes | ACE2 | Gene:59272 |
| 698 | 21618-21657 | Chemical | denotes | N‐(2‐aminoethyl)‐1 aziridine‐ethanamine | |
| 699 | 21755-21767 | Disease | denotes | cytotoxicity | MESH:D064420 |
| 705 | 21861-21865 | Gene | denotes | ACE2 | Gene:59272 |
| 706 | 21867-21870 | Gene | denotes | ACE | Gene:1636 |
| 707 | 21872-21901 | Gene | denotes | angiotensin‐converting enzyme | Gene:1636 |
| 708 | 21834-21842 | Species | denotes | SARS‐CoV | Tax:694009 |
| 709 | 21903-21911 | Species | denotes | SARS‐CoV | Tax:694009 |
| 716 | 22489-22493 | Gene | denotes | IL‐6 | Gene:3569 |
| 717 | 21959-21970 | Chemical | denotes | Chloroquine | MESH:D002738 |
| 718 | 22412-22423 | Chemical | denotes | chloroquine | MESH:D002738 |
| 719 | 22060-22067 | Disease | denotes | malaria | MESH:D008288 |
| 720 | 22072-22081 | Disease | denotes | amebiasis | MESH:D000562 |
| 721 | 22552-22556 | Disease | denotes | ARDS | MESH:D012128 |
| 735 | 23069-23073 | Gene | denotes | ACE2 | Gene:59272 |
| 736 | 23120-23124 | Gene | denotes | ACE2 | Gene:59272 |
| 737 | 22611-22619 | Species | denotes | SARS‐CoV | Tax:694009 |
| 738 | 22623-22631 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 739 | 22637-22647 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 740 | 22673-22683 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 741 | 22755-22763 | Species | denotes | SARS‐CoV | Tax:694009 |
| 742 | 23054-23062 | Species | denotes | SARS‐CoV | Tax:694009 |
| 743 | 23159-23167 | Species | denotes | SARS‐CoV | Tax:694009 |
| 744 | 22872-22883 | Species | denotes | respiratory | Tax:12814 |
| 745 | 22561-22572 | Chemical | denotes | Chloroquine | MESH:D002738 |
| 746 | 22947-22958 | Chemical | denotes | chloroquine | MESH:D002738 |
| 747 | 22963-22983 | Disease | denotes | SARS‐CoV‐1 infection | MESH:C000657245 |
| 755 | 23187-23197 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 756 | 23382-23390 | Species | denotes | patients | Tax:9606 |
| 757 | 23208-23219 | Chemical | denotes | chloroquine | MESH:D002738 |
| 758 | 23599-23620 | Chemical | denotes | chloroquine phosphate | MESH:C023676 |
| 759 | 23332-23340 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 760 | 23396-23409 | Disease | denotes | heart disease | MESH:D006331 |
| 761 | 23413-23421 | Disease | denotes | diabetes | MESH:D003920 |
| 764 | 23640-23658 | Chemical | denotes | Hydroxychloroquine | MESH:D006886 |
| 765 | 23723-23731 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 781 | 23843-23853 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 782 | 24026-24037 | Species | denotes | Ebola virus | Tax:1570291 |
| 783 | 24145-24153 | Species | denotes | patients | Tax:9606 |
| 784 | 24504-24512 | Species | denotes | patients | Tax:9606 |
| 785 | 24630-24638 | Species | denotes | patients | Tax:9606 |
| 786 | 24767-24775 | Species | denotes | patients | Tax:9606 |
| 787 | 23803-23821 | Chemical | denotes | Hydroxychloroquine | MESH:D006886 |
| 788 | 23940-23958 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
| 789 | 23963-23975 | Chemical | denotes | azithromycin | MESH:D017963 |
| 790 | 23977-23989 | Chemical | denotes | Azithromycin | MESH:D017963 |
| 791 | 24219-24237 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
| 792 | 24281-24293 | Chemical | denotes | azithromycin | MESH:D017963 |
| 793 | 24407-24425 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
| 794 | 24476-24488 | Chemical | denotes | azithromycin | MESH:D017963 |
| 795 | 24169-24185 | Disease | denotes | viral infections | MESH:D001102 |
| 801 | 25157-25165 | Species | denotes | patients | Tax:9606 |
| 802 | 24881-24892 | Chemical | denotes | chloroquine | MESH:D002738 |
| 803 | 24912-24930 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
| 804 | 25030-25038 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 805 | 25148-25156 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 822 | 25213-25221 | Species | denotes | patients | Tax:9606 |
| 823 | 25478-25486 | Species | denotes | patients | Tax:9606 |
| 824 | 25543-25551 | Species | denotes | patients | Tax:9606 |
| 825 | 25289-25307 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
| 826 | 25311-25322 | Chemical | denotes | chloroquine | MESH:D002738 |
| 827 | 25365-25374 | Chemical | denotes | macrolide | MESH:D018942 |
| 828 | 25383-25395 | Chemical | denotes | azithromycin | MESH:D017963 |
| 829 | 25400-25414 | Chemical | denotes | clarithromycin | MESH:D017291 |
| 830 | 25791-25802 | Chemical | denotes | chloroquine | MESH:D002738 |
| 831 | 25807-25825 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
| 832 | 25991-26009 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
| 833 | 25227-25235 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 834 | 25588-25610 | Disease | denotes | ventricular arrhythmia | MESH:D001145 |
| 835 | 25752-25760 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 836 | 25881-25900 | Disease | denotes | autoimmune diseases | MESH:D001327 |
| 837 | 25905-25912 | Disease | denotes | malaria | MESH:D008288 |
| 851 | 26088-26092 | Gene | denotes | ACE2 | Gene:59272 |
| 852 | 26183-26218 | Gene | denotes | A disintegrin and metalloproteinase | |
| 853 | 26220-26224 | Gene | denotes | ADAM | |
| 854 | 26241-26264 | Gene | denotes | TNF‐α converting enzyme | Gene:6868 |
| 855 | 26266-26270 | Gene | denotes | TACE | Gene:6868 |
| 856 | 26309-26313 | Gene | denotes | ACE2 | Gene:59272 |
| 857 | 26368-26372 | Gene | denotes | ACE2 | Gene:59272 |
| 858 | 26464-26468 | Gene | denotes | ACE2 | Gene:59272 |
| 859 | 26486-26490 | Gene | denotes | TACE | Gene:6868 |
| 860 | 26550-26554 | Gene | denotes | ACE2 | Gene:59272 |
| 861 | 26374-26383 | Chemical | denotes | GW280264X | MESH:C492546 |
| 862 | 26503-26509 | Chemical | denotes | TAPI‐0 | |
| 863 | 26519-26525 | Chemical | denotes | TAPI‐2 | MESH:C099410 |
| 868 | 26678-26682 | Gene | denotes | ACE2 | Gene:59272 |
| 869 | 26803-26807 | Gene | denotes | ACE2 | Gene:59272 |
| 870 | 26797-26802 | Species | denotes | human | Tax:9606 |
| 871 | 26873-26883 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 877 | 27149-27153 | Gene | denotes | ACE2 | Gene:59272 |
| 878 | 27438-27448 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 879 | 27288-27297 | Species | denotes | influenza | Tax:11309 |
| 880 | 27206-27216 | Chemical | denotes | Umifenovir | MESH:C086979 |
| 881 | 27233-27240 | Chemical | denotes | Arbidol | MESH:C086979 |
| 893 | 27562-27566 | Gene | denotes | ACE2 | Gene:59272 |
| 894 | 27853-27857 | Gene | denotes | ACE2 | Gene:59272 |
| 895 | 27962-27966 | Gene | denotes | ACE2 | Gene:59272 |
| 896 | 27484-27494 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 897 | 27589-27599 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 898 | 27716-27724 | Species | denotes | patients | Tax:9606 |
| 899 | 27781-27789 | Species | denotes | patients | Tax:9606 |
| 900 | 27875-27883 | Species | denotes | patients | Tax:9606 |
| 901 | 27546-27554 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 902 | 27707-27715 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 903 | 27889-27902 | Disease | denotes | heart disease | MESH:D006331 |
| 908 | 28194-28198 | Gene | denotes | ACE2 | Gene:59272 |
| 909 | 28302-28306 | Gene | denotes | ACE2 | Gene:59272 |
| 910 | 28139-28147 | Species | denotes | patients | Tax:9606 |
| 911 | 28247-28255 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 913 | 28365-28368 | Disease | denotes | AHA | |
| 916 | 28650-28658 | Species | denotes | SARS‐CoV | Tax:694009 |
| 917 | 28795-28808 | Disease | denotes | lung diseases | MESH:D008171 |
| 919 | 28853-28857 | Species | denotes | CoVs | Tax:11118 |
| 924 | 29435-29439 | Gene | denotes | ACE2 | Gene:59272 |
| 925 | 29487-29492 | Gene | denotes | CD147 | Gene:682 |
| 926 | 29073-29076 | Species | denotes | CoV | Tax:11118 |
| 927 | 29440-29450 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 938 | 29661-29672 | Gene | denotes | cathepsin L | Gene:1514 |
| 939 | 29674-29681 | Gene | denotes | TMPRSS2 | Gene:7113 |
| 940 | 29987-29994 | Gene | denotes | TMPRSS2 | Gene:7113 |
| 941 | 30060-30065 | Gene | denotes | Furin | Gene:103231185 |
| 942 | 29578-29581 | Species | denotes | CoV | Tax:11118 |
| 943 | 30100-30108 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 944 | 30069-30075 | Chemical | denotes | serine | MESH:D012694 |
| 945 | 29935-29949 | Disease | denotes | CoV infections | MESH:D018352 |
| 946 | 30023-30042 | Disease | denotes | SARS‐CoV‐2‐infected | MESH:C000657245 |
| 947 | 30043-30049 | CellLine | denotes | VeroE6 | CVCL:0574 |
| 960 | 30310-30318 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 961 | 30323-30331 | Species | denotes | SARS‐CoV | Tax:694009 |
| 962 | 30483-30488 | Species | denotes | human | Tax:9606 |
| 963 | 30489-30492 | Species | denotes | CoV | Tax:11118 |
| 964 | 30499-30516 | Species | denotes | hepatitis C virus | Tax:11103 |
| 965 | 30518-30545 | Species | denotes | infectious bronchitis virus | Tax:11120 |
| 966 | 30558-30579 | Species | denotes | mouse hepatitis virus | Tax:11138 |
| 967 | 30493-30497 | Species | denotes | 229E | Tax:11137 |
| 968 | 30212-30226 | Chemical | denotes | chlorpromazine | MESH:D002746 |
| 969 | 30233-30245 | Chemical | denotes | promethazine | MESH:D011398 |
| 970 | 30256-30268 | Chemical | denotes | fluphenazine | MESH:D005476 |
| 971 | 30391-30405 | Chemical | denotes | Chlorpromazine | MESH:D002746 |
| 978 | 30844-30851 | Gene | denotes | TMPRSS2 | Gene:7113 |
| 979 | 31163-31189 | Gene | denotes | EST (a cathepsin inhibitor | Gene:6783 |
| 980 | 30813-30821 | Species | denotes | SARS‐CoV | Tax:694009 |
| 981 | 30946-30954 | Species | denotes | SARS‐CoV | Tax:694009 |
| 982 | 30755-30761 | Chemical | denotes | serine | MESH:D012694 |
| 983 | 31229-31238 | Disease | denotes | infection | MESH:D007239 |
| 987 | 31314-31321 | Gene | denotes | TMPRSS2 | Gene:7113 |
| 988 | 31323-31329 | Gene | denotes | TMPRSS | Gene:3003 |
| 989 | 31345-31351 | Chemical | denotes | serine | MESH:D012694 |
| 994 | 31428-31438 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 995 | 31602-31610 | Species | denotes | SARS‐CoV | Tax:694009 |
| 996 | 31551-31572 | Gene | denotes | a cathepsin inhibitor | Gene:6783 |
| 997 | 31544-31549 | Chemical | denotes | E‐64d | |
| 1002 | 31757-31774 | Gene | denotes | cysteine protease | Gene:1508 |
| 1003 | 32036-32043 | Gene | denotes | TMPRSS2 | Gene:7113 |
| 1004 | 31826-31834 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1005 | 31841-31849 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 1020 | 32333-32344 | Gene | denotes | cathepsin L | Gene:1514 |
| 1021 | 32168-32189 | Species | denotes | Staphylococcus aureus | Tax:1280 |
| 1022 | 32194-32215 | Species | denotes | Enterococcus faecalis | Tax:1351 |
| 1023 | 32269-32277 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1024 | 32281-32289 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 1025 | 32295-32306 | Species | denotes | Ebola virus | Tax:1570291 |
| 1026 | 32411-32421 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 1027 | 32045-32056 | Chemical | denotes | Teicoplanin | MESH:D017334 |
| 1028 | 32062-32074 | Chemical | denotes | glycopeptide | MESH:D006020 |
| 1029 | 32146-32157 | Chemical | denotes | methicillin | MESH:D008712 |
| 1030 | 32235-32246 | Chemical | denotes | teicoplanin | MESH:D017334 |
| 1031 | 32478-32489 | Chemical | denotes | teicoplanin | MESH:D017334 |
| 1032 | 32102-32112 | Disease | denotes | infections | MESH:D007239 |
| 1033 | 32553-32561 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 1035 | 32592-32603 | Gene | denotes | cathepsin L | Gene:1514 |
| 1042 | 32621-32632 | Gene | denotes | cathepsin L | Gene:1514 |
| 1043 | 32615-32620 | Species | denotes | Human | Tax:9606 |
| 1044 | 32972-32980 | Chemical | denotes | MDL28170 | MESH:C058076 |
| 1045 | 32686-32695 | Disease | denotes | infection | MESH:D007239 |
| 1046 | 32928-32941 | Disease | denotes | CoV infection | MESH:D018352 |
| 1047 | 33210-33222 | Disease | denotes | cytotoxicity | MESH:D064420 |
| 1049 | 33273-33284 | Gene | denotes | Cathepsin L | Gene:1514 |
| 1062 | 33437-33448 | Gene | denotes | cathepsin L | Gene:1514 |
| 1063 | 33491-33502 | Gene | denotes | cathepsin L | Gene:1514 |
| 1064 | 33423-33431 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1065 | 33666-33671 | Species | denotes | human | Tax:9606 |
| 1066 | 33752-33757 | Species | denotes | human | Tax:9606 |
| 1067 | 33344-33347 | Disease | denotes | CID | |
| 1068 | 33366-33369 | Disease | denotes | CID | |
| 1069 | 33632-33647 | Disease | denotes | virus infection | MESH:D001102 |
| 1070 | 33672-33688 | Disease | denotes | embryonic kidney | MESH:D007674 |
| 1071 | 33740-33748 | Disease | denotes | toxicity | MESH:D064420 |
| 1072 | 33866-33888 | Disease | denotes | Ebola virus infections | MESH:D019142 |
| 1073 | 33689-33693 | CellLine | denotes | 293T | CVCL:0063 |
| 1077 | 33981-34043 | Gene | denotes | SSAA09E1 (23; Figure 9) as inhibitor of cathepsin L proteinase | |
| 1078 | 34166-34178 | Disease | denotes | cytotoxicity | MESH:D064420 |
| 1079 | 34107-34111 | CellLine | denotes | 293T | CVCL:0063 |
| 1087 | 34699-34703 | Gene | denotes | ACE2 | Gene:59272 |
| 1088 | 34609-34630 | Species | denotes | Polygonum multiflorum | Tax:76025 |
| 1089 | 34635-34651 | Species | denotes | Rheum officinale | Tax:137220 |
| 1090 | 34560-34566 | Chemical | denotes | emodin | MESH:D004642 |
| 1091 | 34962-34971 | Chemical | denotes | benzamide | MESH:C037689 |
| 1092 | 34535-34541 | Disease | denotes | Hsiang | |
| 1093 | 34817-34819 | CellLine | denotes | E6 | CVCL:4582 |
| 1100 | 35457-35466 | Gene | denotes | Cathepsin | |
| 1101 | 35282-35290 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1102 | 35400-35408 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1103 | 35497-35505 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 1104 | 35477-35483 | Chemical | denotes | E‐64‐D | |
| 1105 | 35510-35530 | Disease | denotes | SARS‐CoV‐1 infection | MESH:C000657245 |
| 1114 | 35633-35637 | Gene | denotes | Mpro | Gene:8673700 |
| 1115 | 35980-35984 | Gene | denotes | nsp4 | Gene:400668 |
| 1116 | 35995-35999 | Gene | denotes | Mpro | Gene:8673700 |
| 1117 | 36220-36224 | Gene | denotes | Mpro | Gene:8673700 |
| 1118 | 36162-36166 | Gene | denotes | Mpro | Gene:8673700 |
| 1119 | 35921-35925 | Gene | denotes | Mpro | Gene:8673700 |
| 1120 | 36053-36057 | Gene | denotes | RdRP | Gene:43740578 |
| 1121 | 36196-36205 | Disease | denotes | infection | MESH:D007239 |
| 1123 | 36277-36281 | Gene | denotes | Mpro | Gene:8673700 |
| 1126 | 36331-36335 | Gene | denotes | Mpro | Gene:8673700 |
| 1127 | 36327-36330 | Species | denotes | CoV | Tax:11118 |
| 1138 | 36336-36340 | Gene | denotes | Mpro | Gene:8673700 |
| 1139 | 36616-36620 | Gene | denotes | Mpro | Gene:8673700 |
| 1140 | 36392-36396 | Gene | denotes | Mpro | Gene:8673700 |
| 1141 | 36381-36389 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1142 | 36612-36615 | Species | denotes | CoV | Tax:11118 |
| 1143 | 36358-36375 | Gene | denotes | cysteine protease | Gene:1508 |
| 1144 | 36656-36662 | Chemical | denotes | Cys145 | |
| 1145 | 36663-36668 | Chemical | denotes | His41 | |
| 1146 | 36680-36688 | Chemical | denotes | cysteine | MESH:D003545 |
| 1147 | 36738-36747 | Chemical | denotes | histidine | MESH:D006639 |
| 1150 | 37305-37308 | Species | denotes | CoV | Tax:11118 |
| 1151 | 36929-36942 | Disease | denotes | CoV infection | MESH:D018352 |
| 1153 | 37485-37489 | Gene | denotes | Mpro | Gene:8673700 |
| 1160 | 38261-38265 | Gene | denotes | Mpro | Gene:8673700 |
| 1161 | 37821-37825 | Gene | denotes | Mpro | Gene:8673700 |
| 1162 | 37817-37820 | Species | denotes | CoV | Tax:11118 |
| 1163 | 38250-38258 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1164 | 38010-38018 | Chemical | denotes | cysteine | MESH:D003545 |
| 1165 | 37569-37590 | Disease | denotes | coronavirus infection | MESH:D018352 |
| 1173 | 38464-38468 | Gene | denotes | Mpro | Gene:8673700 |
| 1174 | 38447-38451 | Gene | denotes | Mpro | Gene:8673700 |
| 1175 | 38378-38382 | Gene | denotes | Mpro | Gene:8673700 |
| 1176 | 38367-38375 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1177 | 38438-38446 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1178 | 38485-38493 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1179 | 38495-38540 | Species | denotes | severe acute respiratory syndrome coronavirus | Tax:694009 |
| 1200 | 39447-39451 | Gene | denotes | Mpro | Gene:8673700 |
| 1201 | 38720-38724 | Gene | denotes | Mpro | Gene:8673700 |
| 1202 | 39355-39359 | Gene | denotes | Mpro | Gene:8673700 |
| 1203 | 39184-39188 | Gene | denotes | Mpro | Gene:8673700 |
| 1204 | 39005-39009 | Gene | denotes | Mpro | Gene:8673700 |
| 1205 | 38709-38717 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1206 | 38999-39003 | Species | denotes | TGEV | Tax:11149 |
| 1207 | 39173-39181 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1208 | 39260-39278 | Species | denotes | human rhinovirus 3 | Tax:44130 |
| 1209 | 39350-39354 | Species | denotes | TGEV | Tax:11149 |
| 1210 | 39436-39444 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1211 | 38964-38977 | Species | denotes | transmissible | Tax:11149 |
| 1212 | 38762-38809 | Chemical | denotes | Cbz‐Val‐Asn‐Ser‐Thr‐Leu‐Gln‐chloromethyl ketone | |
| 1213 | 38837-38856 | Chemical | denotes | chloromethyl ketone | |
| 1214 | 39054-39056 | Chemical | denotes | P1 | MESH:C480041 |
| 1215 | 39057-39060 | Chemical | denotes | Gln | MESH:D005973 |
| 1216 | 39123-39130 | Chemical | denotes | leucine | MESH:D007930 |
| 1217 | 39204-39215 | Chemical | denotes | rupintrivir | MESH:C118874 |
| 1218 | 39221-39227 | Chemical | denotes | AG7088 | MESH:C118874 |
| 1219 | 38978-38997 | Disease | denotes | gastroenteritis CoV | MESH:C000657245 |
| 1229 | 40410-40414 | Gene | denotes | Mpro | Gene:8673700 |
| 1230 | 39518-39522 | Gene | denotes | Mpro | Gene:8673700 |
| 1231 | 39507-39515 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1232 | 40401-40409 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 1233 | 39743-39752 | Chemical | denotes | P1‐lactam | |
| 1234 | 40507-40513 | Chemical | denotes | serine | MESH:D012694 |
| 1235 | 40539-40547 | Chemical | denotes | hydrogen | MESH:D006859 |
| 1236 | 40742-40751 | Chemical | denotes | isoprenyl | |
| 1237 | 40291-40303 | Disease | denotes | cytotoxicity | MESH:D064420 |
| 1242 | 40853-40857 | Gene | denotes | Mpro | Gene:8673700 |
| 1243 | 40917-40921 | Gene | denotes | Mpro | Gene:8673700 |
| 1244 | 40844-40852 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1245 | 40938-40946 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1255 | 41899-41908 | Species | denotes | HCoV‐229E | Tax:11137 |
| 1256 | 41299-41308 | Chemical | denotes | P1‐lactam | |
| 1257 | 41389-41397 | Chemical | denotes | hydrogen | MESH:D006859 |
| 1258 | 41481-41488 | Chemical | denotes | leucine | MESH:D007930 |
| 1259 | 41558-41574 | Chemical | denotes | P2‐phenylalanine | |
| 1260 | 41578-41600 | Chemical | denotes | ‐4‐fluorophenylalanine | MESH:D010135 |
| 1261 | 41669-41671 | Chemical | denotes | P3 | |
| 1262 | 41688-41697 | Chemical | denotes | P3‐valine | |
| 1263 | 41732-41750 | Chemical | denotes | P4‐methylisoxazole | |
| 1266 | 42198-42238 | Chemical | denotes | Phe‐Phe‐dipeptidic α,β‐unsaturated ester | |
| 1267 | 42468-42483 | Chemical | denotes | 4‐dimethylamine | |
| 1277 | 42855-42859 | Gene | denotes | Mpro | Gene:8673700 |
| 1278 | 42793-42797 | Gene | denotes | Mpro | Gene:8673700 |
| 1279 | 42642-42650 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1280 | 42770-42774 | Species | denotes | CoVs | Tax:11118 |
| 1281 | 42784-42792 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 1282 | 42819-42828 | Species | denotes | HCoV‐229E | Tax:11137 |
| 1283 | 42830-42839 | Species | denotes | HCoV‐NL63 | Tax:277944 |
| 1284 | 42845-42854 | Species | denotes | HCoV‐HKU1 | Tax:290028 |
| 1285 | 42955-42982 | Species | denotes | infectious bronchitis virus | Tax:11120 |
| 1307 | 43360-43364 | Gene | denotes | Mpro | Gene:8673700 |
| 1308 | 43520-43524 | Gene | denotes | Mpro | Gene:8673700 |
| 1309 | 43692-43696 | Gene | denotes | Mpro | Gene:8673700 |
| 1310 | 43559-43560 | Gene | denotes | M | Gene:43740571 |
| 1311 | 43619-43623 | Gene | denotes | Mpro | Gene:8673700 |
| 1312 | 43466-43470 | Gene | denotes | Mpro | Gene:8673700 |
| 1313 | 43406-43410 | Gene | denotes | Mpro | Gene:8673700 |
| 1314 | 43028-43038 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 1315 | 43087-43095 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1316 | 43229-43239 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 1317 | 43268-43276 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1318 | 43349-43357 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1319 | 43395-43405 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 1320 | 43455-43465 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 1321 | 43488-43492 | Species | denotes | kobs | Tax:59530 |
| 1322 | 43505-43519 | Species | denotes | COVID‐19 virus | Tax:2697049 |
| 1323 | 43608-43616 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1324 | 43681-43691 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 1325 | 43732-43735 | Species | denotes | CoV | Tax:11118 |
| 1326 | 43573-43583 | Chemical | denotes | Peptide N3 | |
| 1327 | 43782-43789 | Chemical | denotes | Cys‐His | |
| 1333 | 43932-43936 | Gene | denotes | Mpro | Gene:8673700 |
| 1334 | 44062-44066 | Gene | denotes | Mpro | Gene:8673700 |
| 1335 | 44227-44231 | Gene | denotes | Mpro | Gene:8673700 |
| 1336 | 43991-43995 | Gene | denotes | Mpro | Gene:8673700 |
| 1337 | 43917-43931 | Species | denotes | COVID‐19 virus | Tax:2697049 |
| 1343 | 44443-44451 | Chemical | denotes | cysteine | MESH:D003545 |
| 1344 | 44508-44516 | Chemical | denotes | cysteine | MESH:D003545 |
| 1345 | 44626-44637 | Chemical | denotes | α‐carbanion | |
| 1346 | 44643-44646 | Chemical | denotes | His | MESH:D006639 |
| 1347 | 44732-44740 | Chemical | denotes | cysteine | MESH:D003545 |
| 1349 | 44892-44900 | Chemical | denotes | aldehyde | MESH:D000447 |
| 1355 | 45209-45228 | Species | denotes | rodents and rabbits | Tax:314147 |
| 1356 | 44965-44976 | Chemical | denotes | 1,4‐Michael | |
| 1357 | 45115-45131 | Chemical | denotes | carboxylic acids | MESH:D002264 |
| 1358 | 45167-45173 | Chemical | denotes | AG7088 | MESH:C118874 |
| 1359 | 45018-45025 | Disease | denotes | CH═CH–C | MESH:C537418 |
| 1373 | 45821-45825 | Gene | denotes | Mpro | Gene:8673700 |
| 1374 | 45796-45804 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1375 | 45811-45820 | Species | denotes | HCoV‐229E | Tax:11137 |
| 1376 | 45923-45931 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1377 | 45962-45971 | Species | denotes | HCoV‐229E | Tax:11137 |
| 1378 | 46001-46004 | Species | denotes | rat | Tax:10116 |
| 1379 | 46006-46011 | Species | denotes | mouse | Tax:10090 |
| 1380 | 46017-46022 | Species | denotes | human | Tax:9606 |
| 1381 | 45502-45510 | Chemical | denotes | cysteine | MESH:D003545 |
| 1382 | 45536-45544 | Chemical | denotes | aldehyde | MESH:D000447 |
| 1383 | 45573-45580 | Chemical | denotes | leucine | MESH:D007930 |
| 1384 | 45649-45657 | Chemical | denotes | aldehyde | MESH:D000447 |
| 1385 | 45737-45745 | Chemical | denotes | aldehyde | MESH:D000447 |
| 1392 | 46190-46194 | Gene | denotes | Mpro | Gene:8673700 |
| 1393 | 46137-46141 | Gene | denotes | Mpro | Gene:8673700 |
| 1394 | 46113-46121 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1395 | 46128-46136 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 1396 | 46211-46219 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1397 | 46166-46174 | Chemical | denotes | aldehyde | MESH:D000447 |
| 1410 | 46473-46477 | Gene | denotes | Mpro | Gene:8673700 |
| 1411 | 46634-46638 | Gene | denotes | Mpro | Gene:8673700 |
| 1412 | 46667-46671 | Gene | denotes | Mpro | Gene:8673700 |
| 1413 | 46492-46500 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1414 | 46507-46515 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 1415 | 46623-46631 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1416 | 46658-46666 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 1417 | 46892-46897 | Species | denotes | human | Tax:9606 |
| 1418 | 46907-46911 | Species | denotes | CoVs | Tax:11118 |
| 1419 | 46312-46328 | Chemical | denotes | peptide‐aldehyde | |
| 1420 | 46525-46537 | Disease | denotes | cytotoxicity | MESH:D064420 |
| 1421 | 46805-46817 | Disease | denotes | CoV‐infected | MESH:D018352 |
| 1434 | 46960-46964 | Gene | denotes | Mpro | Gene:8673700 |
| 1435 | 47101-47105 | Gene | denotes | Mpro | Gene:8673700 |
| 1436 | 47389-47393 | Gene | denotes | Mpro | Gene:8673700 |
| 1437 | 47531-47535 | Gene | denotes | Mpro | Gene:8673700 |
| 1438 | 46949-46957 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1439 | 47141-47144 | Species | denotes | SAR | Tax:2698737 |
| 1440 | 47187-47199 | Chemical | denotes | P1‐imidazole | |
| 1441 | 47623-47631 | Chemical | denotes | nitrogen | MESH:D009584 |
| 1442 | 47647-47655 | Chemical | denotes | hydrogen | MESH:D006859 |
| 1443 | 47670-47679 | Chemical | denotes | histidine | MESH:D006639 |
| 1444 | 47700-47708 | Chemical | denotes | nitrogen | MESH:D009584 |
| 1445 | 47068-47090 | Disease | denotes | Val‐Leu‐N(CH3)2Gln‐CHO | MESH:C536108 |
| 1453 | 48218-48222 | Gene | denotes | Mpro | Gene:8673700 |
| 1454 | 48164-48168 | Gene | denotes | Mpro | Gene:8673700 |
| 1455 | 48155-48163 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1456 | 47948-47969 | Chemical | denotes | decahydroisoquinoline | |
| 1457 | 48260-48284 | Chemical | denotes | P2‐decahydroisoquinoline | |
| 1458 | 48345-48354 | Chemical | denotes | imidazole | MESH:C029899 |
| 1459 | 48492-48496 | Disease | denotes | fits | MESH:D012640 |
| 1462 | 48568-48578 | Chemical | denotes | cyclohexyl | |
| 1463 | 48583-48604 | Chemical | denotes | decahydroisoquinoline | |
| 1466 | 48969-48973 | Gene | denotes | Mpro | Gene:8673700 |
| 1467 | 48858-48879 | Chemical | denotes | decahydroisoquinoline | |
| 1472 | 49167-49187 | Chemical | denotes | octahydroisochromene | |
| 1473 | 49388-49416 | Chemical | denotes | (1S,3S)‐octahydroisochromene | |
| 1474 | 49464-49476 | Chemical | denotes | P1‐imidazole | |
| 1475 | 49492-49500 | Chemical | denotes | aldehyde | MESH:D000447 |
| 1487 | 49786-49790 | Gene | denotes | Mpro | Gene:8673700 |
| 1488 | 49762-49770 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 1489 | 49775-49783 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1490 | 50024-50028 | Species | denotes | CoVs | Tax:11118 |
| 1491 | 50041-50076 | Species | denotes | feline infectious peritonitis virus | Tax:11135 |
| 1492 | 50078-50082 | Species | denotes | FIPV | Tax:11135 |
| 1493 | 50145-50153 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 1494 | 50219-50222 | Species | denotes | SAR | Tax:2698737 |
| 1495 | 49817-49830 | Chemical | denotes | P3‐piperidine | |
| 1496 | 49897-49926 | Chemical | denotes | dipeptidic‐aldehyde bisulfite | |
| 1497 | 50249-50259 | Chemical | denotes | piperidine | MESH:C032727 |
| 1501 | 50382-50390 | Chemical | denotes | aldehyde | MESH:D000447 |
| 1502 | 50392-50410 | Chemical | denotes | aldehyde bisulfite | |
| 1503 | 50423-50430 | Chemical | denotes | epoxide | MESH:D004852 |
| 1509 | 50477-50485 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 1510 | 50538-50548 | Chemical | denotes | piperidine | MESH:C032727 |
| 1511 | 50652-50658 | Chemical | denotes | Gln192 | |
| 1512 | 50660-50666 | Chemical | denotes | Gln167 | |
| 1513 | 50672-50678 | Chemical | denotes | Glu169 | |
| 1525 | 50739-50743 | Gene | denotes | Mpro | Gene:8673700 |
| 1526 | 51009-51013 | Gene | denotes | Mpro | Gene:8673700 |
| 1527 | 50975-50979 | Gene | denotes | Mpro | Gene:8673700 |
| 1528 | 50701-50705 | Species | denotes | APEs | Tax:4456 |
| 1529 | 50728-50736 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1530 | 50966-50974 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1531 | 50680-50699 | Chemical | denotes | Azapeptide epoxides | |
| 1532 | 50845-50852 | Chemical | denotes | epoxide | MESH:D004852 |
| 1533 | 51088-51098 | Chemical | denotes | cysteine‐S | |
| 1534 | 51112-51119 | Chemical | denotes | epoxide | MESH:D004852 |
| 1535 | 51153-51175 | Chemical | denotes | S,S‐configured epoxide | |
| 1544 | 51293-51297 | Gene | denotes | Mpro | Gene:8673700 |
| 1545 | 51394-51398 | Gene | denotes | Mpro | Gene:8673700 |
| 1546 | 51663-51667 | Gene | denotes | Mpro | Gene:8673700 |
| 1547 | 51282-51292 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 1548 | 51652-51662 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 1549 | 51781-51789 | Chemical | denotes | aldehyde | MESH:D000447 |
| 1550 | 51848-51854 | Chemical | denotes | Cys145 | |
| 1551 | 51893-51905 | Disease | denotes | Cytotoxicity | MESH:D064420 |
| 1557 | 52035-52039 | Gene | denotes | Mpro | Gene:8673700 |
| 1558 | 51996-52000 | Gene | denotes | Mpro | Gene:8673700 |
| 1559 | 51985-51995 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 1560 | 52056-52064 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1561 | 52017-52026 | Chemical | denotes | P3‐indole | |
| 1563 | 52120-52129 | Chemical | denotes | Ketoamide | |
| 1575 | 52264-52268 | Species | denotes | CoVs | Tax:11118 |
| 1576 | 52596-52604 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1577 | 52605-52609 | Gene | denotes | Mpro | Gene:8673700 |
| 1578 | 52161-52184 | Chemical | denotes | dipeptidic α‐ketoamides | |
| 1579 | 52316-52327 | Chemical | denotes | α‐ketoamide | |
| 1580 | 52376-52384 | Chemical | denotes | hydrogen | MESH:D006859 |
| 1581 | 52435-52440 | Chemical | denotes | amide | MESH:D000577 |
| 1582 | 52441-52447 | Chemical | denotes | oxygen | MESH:D010100 |
| 1583 | 52503-52509 | Chemical | denotes | esters | MESH:D004952 |
| 1584 | 52514-52523 | Chemical | denotes | aldehydes | MESH:D000447 |
| 1585 | 52542-52550 | Chemical | denotes | hydrogen | MESH:D006859 |
| 1591 | 52720-52724 | Gene | denotes | Mpro | Gene:8673700 |
| 1592 | 52726-52730 | Gene | denotes | Mpro | Gene:8673700 |
| 1593 | 52709-52719 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 1594 | 52747-52755 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1595 | 52678-52687 | Chemical | denotes | Ketoamide | |
| 1603 | 53184-53188 | Gene | denotes | Mpro | Gene:8673700 |
| 1604 | 52869-52877 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1605 | 52881-52890 | Species | denotes | HCoV‐NL63 | Tax:277944 |
| 1606 | 52896-52910 | Species | denotes | coxsackievirus | Tax:12066 |
| 1607 | 53173-53181 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1608 | 53111-53125 | Chemical | denotes | P2‐cyclopentyl | |
| 1609 | 53193-53197 | CellLine | denotes | Huh7 | CVCL:0336 |
| 1625 | 53658-53662 | Gene | denotes | Mpro | Gene:8673700 |
| 1626 | 53915-53919 | Gene | denotes | Mpro | Gene:8673700 |
| 1627 | 53843-53847 | Gene | denotes | Mpro | Gene:8673700 |
| 1628 | 53771-53775 | Gene | denotes | Mpro | Gene:8673700 |
| 1629 | 53520-53524 | Gene | denotes | Mpro | Gene:8673700 |
| 1630 | 53500-53504 | Gene | denotes | Mpro | Gene:8673700 |
| 1631 | 53489-53497 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1632 | 53509-53519 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 1633 | 53647-53657 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 1634 | 53760-53770 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 1635 | 53832-53840 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1636 | 53904-53914 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 1637 | 54046-54048 | Chemical | denotes | P2 | MESH:C020845 |
| 1638 | 54052-54057 | Chemical | denotes | amide | MESH:D000577 |
| 1639 | 54072-54080 | Chemical | denotes | pyridone | MESH:D011728 |
| 1645 | 54331-54335 | Gene | denotes | Mpro | Gene:8673700 |
| 1646 | 54320-54324 | Gene | denotes | Mpro | Gene:8673700 |
| 1647 | 54309-54319 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 1648 | 54352-54360 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1649 | 54362-54407 | Species | denotes | severe acute respiratory syndrome coronavirus | Tax:694009 |
| 1655 | 54984-54988 | Gene | denotes | Mpro | Gene:8673700 |
| 1656 | 54531-54535 | Species | denotes | mice | Tax:10090 |
| 1657 | 54836-54841 | Species | denotes | mouse | Tax:10090 |
| 1658 | 54973-54983 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 1659 | 55164-55179 | Species | denotes | β‐coronaviruses | Tax:694002 |
| 1671 | 55328-55332 | Gene | denotes | Mpro | Gene:8673700 |
| 1672 | 55294-55298 | Gene | denotes | Mpro | Gene:8673700 |
| 1673 | 55235-55239 | Gene | denotes | Mpro | Gene:8673700 |
| 1674 | 55224-55234 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 1675 | 55283-55291 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1676 | 55319-55327 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 1677 | 55396-55404 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1678 | 55473-55478 | Species | denotes | human | Tax:9606 |
| 1679 | 55947-55951 | Species | denotes | mice | Tax:10090 |
| 1680 | 55453-55472 | Disease | denotes | SARS‐CoV‐2 infected | MESH:C000657245 |
| 1681 | 55479-55484 | CellLine | denotes | Calu3 | CVCL:0609 |
| 1703 | 56523-56540 | Gene | denotes | cysteine protease | Gene:1508 |
| 1704 | 56276-56285 | Chemical | denotes | thioketal | |
| 1705 | 56322-56328 | Chemical | denotes | Cys145 | |
| 1706 | 56385-56390 | Chemical | denotes | His41 | |
| 1707 | 56404-56409 | Chemical | denotes | amide | MESH:D000577 |
| 1708 | 56410-56416 | Chemical | denotes | oxygen | MESH:D010100 |
| 1709 | 56460-56466 | Chemical | denotes | amides | MESH:D000577 |
| 1710 | 56470-56476 | Chemical | denotes | Gly143 | |
| 1711 | 56478-56484 | Chemical | denotes | Cys145 | |
| 1712 | 56499-56505 | Chemical | denotes | Ser144 | |
| 1713 | 56580-56586 | Chemical | denotes | lactam | MESH:D007769 |
| 1714 | 56640-56646 | Chemical | denotes | lactam | MESH:D007769 |
| 1715 | 56647-56655 | Chemical | denotes | nitrogen | MESH:D009584 |
| 1716 | 56704-56710 | Chemical | denotes | oxygen | MESH:D010100 |
| 1717 | 56718-56724 | Chemical | denotes | Phe140 | |
| 1718 | 56748-56754 | Chemical | denotes | Glu166 | |
| 1719 | 56769-56775 | Chemical | denotes | oxygen | MESH:D010100 |
| 1720 | 56794-56800 | Chemical | denotes | His163 | |
| 1721 | 56858-56872 | Chemical | denotes | P3‐P2 pyridone | |
| 1722 | 57028-57034 | Chemical | denotes | Pro168 | |
| 1723 | 56828-56832 | Disease | denotes | fits | MESH:D012640 |
| 1729 | 57178-57182 | Gene | denotes | Mpro | Gene:8673700 |
| 1730 | 57184-57188 | Gene | denotes | Mpro | Gene:8673700 |
| 1731 | 57167-57177 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 1732 | 57205-57213 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1733 | 57215-57260 | Species | denotes | severe acute respiratory syndrome coronavirus | Tax:694009 |
| 1735 | 57354-57360 | Chemical | denotes | ketone | MESH:D007659 |
| 1741 | 57398-57404 | Chemical | denotes | ketone | MESH:D007659 |
| 1742 | 57568-57574 | Chemical | denotes | Ser‐OH | |
| 1743 | 57578-57581 | Chemical | denotes | Cys | MESH:D003545 |
| 1744 | 57636-57642 | Chemical | denotes | serine | MESH:D012694 |
| 1745 | 57525-57538 | Disease | denotes | hemithioketal | |
| 1747 | 57751-57757 | Chemical | denotes | ketone | MESH:D007659 |
| 1764 | 58447-58451 | Gene | denotes | Mpro | Gene:8673700 |
| 1765 | 58082-58086 | Gene | denotes | Mpro | Gene:8673700 |
| 1766 | 57979-57983 | Gene | denotes | Mpro | Gene:8673700 |
| 1767 | 57968-57976 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1768 | 58071-58079 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1769 | 57927-57949 | Chemical | denotes | trifluoromethyl ketone | |
| 1770 | 58239-58247 | Chemical | denotes | cysteine | MESH:D003545 |
| 1771 | 58319-58322 | Chemical | denotes | P1‐ | MESH:C480041 |
| 1772 | 58322-58328 | Chemical | denotes | lactam | MESH:D007769 |
| 1773 | 58333-58345 | Chemical | denotes | P1'‐thiazole | |
| 1774 | 58522-58528 | Chemical | denotes | Cys143 | |
| 1775 | 58530-58536 | Chemical | denotes | Ser144 | |
| 1776 | 58542-58548 | Chemical | denotes | Cys145 | |
| 1777 | 58554-58562 | Chemical | denotes | nitrogen | MESH:D009584 |
| 1778 | 58575-58583 | Chemical | denotes | thiazole | MESH:D013844 |
| 1779 | 58644-58653 | Chemical | denotes | P1‐lactam | |
| 1800 | 59545-59549 | Gene | denotes | Mpro | Gene:8673700 |
| 1801 | 59868-59872 | Gene | denotes | Mpro | Gene:8673700 |
| 1802 | 58910-58914 | Gene | denotes | Mpro | Gene:8673700 |
| 1803 | 58918-58926 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1804 | 59857-59865 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1805 | 58743-58753 | Chemical | denotes | tripeptide | |
| 1806 | 58765-58778 | Chemical | denotes | benzothiazole | MESH:C005465 |
| 1807 | 58998-59011 | Chemical | denotes | benzothiazole | MESH:C005465 |
| 1808 | 59116-59126 | Chemical | denotes | dipeptides | MESH:D004151 |
| 1809 | 59208-59217 | Chemical | denotes | P3‐valine | |
| 1810 | 59225-59235 | Chemical | denotes | tripeptide | |
| 1811 | 59315-59327 | Chemical | denotes | N‐arylglycyl | |
| 1812 | 59469-59477 | Chemical | denotes | hydrogen | MESH:D006859 |
| 1813 | 59535-59541 | Chemical | denotes | Glu166 | |
| 1814 | 59578-59585 | Chemical | denotes | leucine | MESH:D007930 |
| 1815 | 59590-59606 | Chemical | denotes | P1'‐benzthiazole | |
| 1816 | 59957-59965 | Chemical | denotes | hydrogen | MESH:D006859 |
| 1817 | 60061-60067 | Chemical | denotes | Glu166 | |
| 1818 | 60223-60229 | Chemical | denotes | indole | MESH:C030374 |
| 1819 | 60235-60245 | Chemical | denotes | benzofuran | MESH:C105430 |
| 1825 | 60348-60352 | Gene | denotes | Mpro | Gene:8673700 |
| 1826 | 60354-60358 | Gene | denotes | Mpro | Gene:8673700 |
| 1827 | 60337-60345 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1828 | 60375-60383 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1829 | 60385-60430 | Species | denotes | severe acute respiratory syndrome coronavirus | Tax:694009 |
| 1831 | 60519-60542 | Chemical | denotes | trifluoromethyl ketones | |
| 1839 | 60867-60871 | Gene | denotes | Mpro | Gene:8673700 |
| 1840 | 60856-60864 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1841 | 60809-60819 | Chemical | denotes | dipeptides | MESH:D004151 |
| 1842 | 60831-60852 | Chemical | denotes | difluoromethyl ketone | |
| 1843 | 60938-60946 | Disease | denotes | infected | MESH:D007239 |
| 1844 | 61032-61040 | Disease | denotes | toxicity | MESH:D064420 |
| 1845 | 60956-60962 | CellLine | denotes | Caco‐2 | CVCL:0025 |
| 1853 | 61115-61119 | Gene | denotes | Mpro | Gene:8673700 |
| 1854 | 61232-61236 | Gene | denotes | Mpro | Gene:8673700 |
| 1855 | 61240-61248 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1856 | 61395-61398 | Species | denotes | SAR | Tax:2698737 |
| 1857 | 61104-61112 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1858 | 61065-61081 | Chemical | denotes | peptide‐anilides | |
| 1859 | 61193-61204 | Chemical | denotes | niclosamide | MESH:D009534 |
| 1869 | 61760-61764 | Gene | denotes | Mpro | Gene:8673700 |
| 1870 | 61749-61757 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1871 | 61868-61871 | Species | denotes | SAR | Tax:2698737 |
| 1872 | 61653-61666 | Chemical | denotes | ketoglutamide | |
| 1873 | 61667-61678 | Chemical | denotes | tripeptides | |
| 1874 | 61978-61986 | Chemical | denotes | hydrogen | MESH:D006859 |
| 1875 | 62098-62104 | Chemical | denotes | Cys‐SH | |
| 1876 | 62180-62189 | Chemical | denotes | P1‐lactam | |
| 1877 | 62199-62204 | Chemical | denotes | nitro | |
| 1884 | 62331-62339 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1885 | 62354-62362 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1886 | 62281-62288 | Chemical | denotes | peptide | MESH:D010455 |
| 1887 | 62289-62297 | Chemical | denotes | anilides | MESH:D000813 |
| 1888 | 62302-62315 | Chemical | denotes | ketoglutamide | |
| 1889 | 62316-62327 | Chemical | denotes | tripeptides | |
| 1900 | 62492-62496 | Gene | denotes | Mpro | Gene:8673700 |
| 1901 | 62591-62595 | Gene | denotes | Mpro | Gene:8673700 |
| 1902 | 62767-62771 | Gene | denotes | Mpro | Gene:8673700 |
| 1903 | 62716-62720 | Gene | denotes | Mpro | Gene:8673700 |
| 1904 | 62481-62489 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1905 | 62580-62588 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1906 | 62705-62713 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1907 | 62808-62817 | Chemical | denotes | hydrogens | MESH:D006859 |
| 1908 | 62860-62866 | Chemical | denotes | His142 | |
| 1909 | 62871-62876 | Chemical | denotes | His41 | |
| 1915 | 62900-62904 | Gene | denotes | Mpro | Gene:8673700 |
| 1916 | 62990-62994 | Gene | denotes | Mpro | Gene:8673700 |
| 1917 | 62889-62897 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1918 | 62960-62988 | Species | denotes | human immunodeficiency virus | Tax:12721 |
| 1919 | 63011-63019 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1921 | 63104-63108 | Gene | denotes | Mpro | Gene:8673700 |
| 1925 | 63224-63228 | Gene | denotes | Mpro | Gene:8673700 |
| 1926 | 63213-63221 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1927 | 63109-63129 | Chemical | denotes | Benzotriazole esters | |
| 1933 | 63497-63501 | Gene | denotes | Mpro | Gene:8673700 |
| 1934 | 63514-63518 | Gene | denotes | Mpro | Gene:8673700 |
| 1935 | 63486-63494 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1936 | 63535-63543 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1937 | 63476-63482 | Chemical | denotes | esters | MESH:D004952 |
| 1945 | 63865-63869 | Gene | denotes | Mpro | Gene:8673700 |
| 1946 | 63854-63862 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1947 | 63634-63653 | Chemical | denotes | benzotriazole ester | |
| 1948 | 63696-63714 | Chemical | denotes | halopyridyl esters | |
| 1949 | 63726-63735 | Chemical | denotes | thiophene | MESH:D013876 |
| 1950 | 63737-63742 | Chemical | denotes | furan | MESH:C039281 |
| 1951 | 63748-63754 | Chemical | denotes | indole | MESH:C030374 |
| 1958 | 64165-64169 | Gene | denotes | Mpro | Gene:8673700 |
| 1959 | 64491-64495 | Gene | denotes | Mpro | Gene:8673700 |
| 1960 | 64387-64391 | Gene | denotes | Mpro | Gene:8673700 |
| 1961 | 64154-64162 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1962 | 64378-64386 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 1963 | 64062-64095 | Chemical | denotes | halopyridinyl indole carboxylates | |
| 1970 | 64605-64609 | Gene | denotes | Mpro | Gene:8673700 |
| 1971 | 64622-64626 | Gene | denotes | Mpro | Gene:8673700 |
| 1972 | 64550-64553 | Species | denotes | SAR | Tax:2698737 |
| 1973 | 64594-64602 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1974 | 64643-64651 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1975 | 64557-64590 | Chemical | denotes | halopyridinyl indole carboxylates | |
| 1985 | 65218-65222 | Gene | denotes | Mpro | Gene:8673700 |
| 1986 | 64844-64853 | Species | denotes | mammalian | Tax:9606 |
| 1987 | 65207-65215 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1988 | 64699-64721 | Chemical | denotes | 5‐Halopyridinyl esters | |
| 1989 | 64920-64926 | Chemical | denotes | thiols | MESH:D013438 |
| 1990 | 65078-65095 | Chemical | denotes | methylene ketones | |
| 1991 | 65110-65152 | Chemical | denotes | mono‐ and di‐fluorinated methylene ketones | |
| 1992 | 65162-65178 | Chemical | denotes | pyridinyl esters | |
| 1993 | 64958-64970 | Disease | denotes | cytotoxicity | MESH:D064420 |
| 2000 | 65437-65441 | Gene | denotes | Mpro | Gene:8673700 |
| 2001 | 65454-65458 | Gene | denotes | Mpro | Gene:8673700 |
| 2002 | 65426-65434 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2003 | 65475-65483 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2004 | 65385-65399 | Chemical | denotes | Etacrynic acid | MESH:D004976 |
| 2005 | 65404-65410 | Chemical | denotes | isatin | MESH:D007510 |
| 2028 | 65658-65662 | Gene | denotes | Mpro | Gene:8673700 |
| 2029 | 66052-66056 | Gene | denotes | Mpro | Gene:8673700 |
| 2030 | 65907-65911 | Gene | denotes | Mpro | Gene:8673700 |
| 2031 | 65778-65782 | Gene | denotes | Mpro | Gene:8673700 |
| 2032 | 65647-65655 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2033 | 65767-65775 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2034 | 65896-65904 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2035 | 65939-65942 | Species | denotes | SAR | Tax:2698737 |
| 2036 | 65597-65611 | Chemical | denotes | etacrynic acid | MESH:D004976 |
| 2037 | 65620-65625 | Chemical | denotes | amide | MESH:D000577 |
| 2038 | 65634-65639 | Chemical | denotes | ester | MESH:D004952 |
| 2039 | 65702-65723 | Chemical | denotes | Etacrynic carboxamide | |
| 2040 | 65814-65834 | Chemical | denotes | etacrynic acid ester | |
| 2041 | 65966-65972 | Chemical | denotes | chloro | |
| 2042 | 66080-66088 | Chemical | denotes | hydrogen | MESH:D006859 |
| 2043 | 66100-66106 | Chemical | denotes | Gln189 | |
| 2044 | 66108-66114 | Chemical | denotes | Glu166 | |
| 2045 | 66116-66122 | Chemical | denotes | Thr190 | |
| 2046 | 66128-66134 | Chemical | denotes | Gln192 | |
| 2047 | 66215-66221 | Chemical | denotes | Gly143 | |
| 2048 | 66273-66279 | Chemical | denotes | Cys145 | |
| 2049 | 66280-66286 | Chemical | denotes | sulfur | MESH:D013455 |
| 2069 | 66621-66625 | Gene | denotes | Mpro | Gene:8673700 |
| 2070 | 67091-67095 | Gene | denotes | Mpro | Gene:8673700 |
| 2071 | 66529-66533 | Gene | denotes | Mpro | Gene:8673700 |
| 2072 | 66474-66478 | Gene | denotes | Mpro | Gene:8673700 |
| 2073 | 66362-66372 | Species | denotes | rhinovirus | Tax:12059 |
| 2074 | 66436-66446 | Species | denotes | rhinovirus | Tax:12059 |
| 2075 | 66463-66471 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2076 | 66518-66526 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2077 | 66610-66618 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2078 | 66680-66683 | Species | denotes | SAR | Tax:2698737 |
| 2079 | 67080-67088 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2080 | 66300-66306 | Chemical | denotes | isatin | MESH:D007510 |
| 2081 | 66308-66323 | Chemical | denotes | 2,3‐dioxoindole | |
| 2082 | 66800-66806 | Chemical | denotes | isatin | MESH:D007510 |
| 2083 | 66951-66957 | Chemical | denotes | isatin | MESH:D007510 |
| 2084 | 66993-66999 | Chemical | denotes | Gly143 | |
| 2085 | 67001-67007 | Chemical | denotes | Ser144 | |
| 2086 | 67009-67015 | Chemical | denotes | Cys145 | |
| 2087 | 67021-67026 | Chemical | denotes | His41 | |
| 2095 | 67382-67386 | Gene | denotes | Mpro | Gene:8673700 |
| 2096 | 67276-67279 | Species | denotes | SAR | Tax:2698737 |
| 2097 | 67371-67379 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2098 | 67343-67354 | Chemical | denotes | carboxamide | |
| 2099 | 67464-67470 | Chemical | denotes | Cys145 | |
| 2100 | 67545-67556 | Chemical | denotes | carboxamide | |
| 2101 | 67594-67606 | Chemical | denotes | sulfonamides | MESH:D013449 |
| 2111 | 67851-67855 | Gene | denotes | Mpro | Gene:8673700 |
| 2112 | 68381-68385 | Gene | denotes | Mpro | Gene:8673700 |
| 2113 | 67840-67848 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2114 | 68097-68101 | Species | denotes | CVB3 | Tax:12072 |
| 2115 | 67789-67799 | Chemical | denotes | pyrazolone | MESH:C038362 |
| 2116 | 67804-67812 | Chemical | denotes | pyrazole | MESH:C031280 |
| 2117 | 68163-68174 | Chemical | denotes | benzylidene | |
| 2118 | 68188-68201 | Chemical | denotes | pyrazolone C4 | |
| 2119 | 68409-68429 | Chemical | denotes | carboxyl benzylidene | |
| 2126 | 68520-68524 | Gene | denotes | Mpro | Gene:8673700 |
| 2127 | 68537-68541 | Gene | denotes | Mpro | Gene:8673700 |
| 2128 | 68509-68517 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2129 | 68558-68566 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2130 | 68480-68489 | Chemical | denotes | Pyrazoles | MESH:D011720 |
| 2131 | 68494-68505 | Chemical | denotes | pyrimidines | MESH:D011743 |
| 2140 | 69033-69037 | Gene | denotes | Mpro | Gene:8673700 |
| 2141 | 68712-68716 | Gene | denotes | Mpro | Gene:8673700 |
| 2142 | 68694-68698 | Gene | denotes | Mpro | Gene:8673700 |
| 2143 | 68683-68691 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2144 | 68703-68711 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 2145 | 69022-69030 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2146 | 68652-68662 | Chemical | denotes | pyrazolone | MESH:C038362 |
| 2147 | 68996-69006 | Chemical | denotes | pyrimidine | MESH:C030986 |
| 2152 | 69270-69274 | Gene | denotes | Mpro | Gene:8673700 |
| 2153 | 69259-69267 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2154 | 69329-69332 | Species | denotes | SAR | Tax:2698737 |
| 2155 | 69200-69209 | Chemical | denotes | dipeptide | MESH:D004151 |
| 2161 | 69477-69481 | Gene | denotes | Mpro | Gene:8673700 |
| 2162 | 69494-69498 | Gene | denotes | Mpro | Gene:8673700 |
| 2163 | 69466-69474 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2164 | 69515-69523 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2165 | 69441-69450 | Chemical | denotes | dipeptide | MESH:D004151 |
| 2179 | 70009-70013 | Gene | denotes | Mpro | Gene:8673700 |
| 2180 | 69899-69903 | Gene | denotes | Mpro | Gene:8673700 |
| 2181 | 69848-69852 | Gene | denotes | Mpro | Gene:8673700 |
| 2182 | 69629-69633 | Gene | denotes | Mpro | Gene:8673700 |
| 2183 | 69618-69626 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2184 | 69837-69845 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2185 | 69998-70006 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2186 | 69867-69874 | Chemical | denotes | (R)‐123 | |
| 2187 | 69980-69987 | Chemical | denotes | (R)‐123 | |
| 2188 | 70091-70098 | Chemical | denotes | (R)‐123 | |
| 2189 | 70148-70156 | Disease | denotes | infected | MESH:D007239 |
| 2190 | 70161-70185 | Disease | denotes | SARS‐CoV‐1 infected Vero | MESH:C000657245 |
| 2191 | 70186-70188 | CellLine | denotes | E6 | CVCL:4582 |
| 2197 | 70284-70288 | Gene | denotes | Mpro | Gene:8673700 |
| 2198 | 70337-70341 | Gene | denotes | Mpro | Gene:8673700 |
| 2199 | 70273-70281 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2200 | 70358-70366 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2201 | 70368-70413 | Species | denotes | severe acute respiratory syndrome coronavirus | Tax:694009 |
| 2209 | 70686-70690 | Gene | denotes | P1 3 | Gene:440926 |
| 2210 | 70505-70508 | Species | denotes | SAR | Tax:2698737 |
| 2211 | 70571-70580 | Chemical | denotes | imidazole | MESH:C029899 |
| 2212 | 70591-70604 | Chemical | denotes | 5‐chlorofuran | |
| 2213 | 70639-70647 | Chemical | denotes | lead 123 | |
| 2214 | 70720-70730 | Chemical | denotes | pyridazine | MESH:C062482 |
| 2215 | 70741-70749 | Chemical | denotes | pyrazine | MESH:D011719 |
| 2221 | 70887-70891 | Gene | denotes | Mpro | Gene:8673700 |
| 2222 | 71023-71027 | Gene | denotes | Mpro | Gene:8673700 |
| 2223 | 70876-70884 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2224 | 71012-71020 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2225 | 70912-70925 | Chemical | denotes | benzotriazole | MESH:C012771 |
| 2231 | 71072-71076 | Gene | denotes | Mpro | Gene:8673700 |
| 2232 | 71127-71131 | Gene | denotes | Mpro | Gene:8673700 |
| 2233 | 71061-71069 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2234 | 71148-71156 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2235 | 71103-71116 | Chemical | denotes | benzotriazole | MESH:C012771 |
| 2243 | 71204-71207 | Species | denotes | SAR | Tax:2698737 |
| 2244 | 71232-71245 | Chemical | denotes | benzotriazole | MESH:C012771 |
| 2245 | 71331-71354 | Chemical | denotes | 4‐phenyl‐1,2,3‐triazole | |
| 2246 | 71447-71456 | Chemical | denotes | acetamide | MESH:C030686 |
| 2247 | 71505-71514 | Chemical | denotes | thiophene | MESH:D013876 |
| 2248 | 71547-71561 | Chemical | denotes | i‐propyl amide | |
| 2249 | 71571-71586 | Chemical | denotes | cyclobutylamide | |
| 2257 | 71848-71852 | Gene | denotes | Mpro | Gene:8673700 |
| 2258 | 71837-71845 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2259 | 71979-71995 | Species | denotes | Torreya nucifera | Tax:50189 |
| 2260 | 72039-72048 | Chemical | denotes | biflavone | |
| 2261 | 72050-72063 | Chemical | denotes | amentoflavone | MESH:C011164 |
| 2262 | 72212-72218 | Chemical | denotes | Val186 | |
| 2263 | 72223-72229 | Chemical | denotes | Gln192 | |
| 2269 | 72365-72381 | Gene | denotes | 3C‐like protease | |
| 2270 | 72338-72346 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2271 | 72383-72391 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2272 | 72271-72278 | Chemical | denotes | Flavone | MESH:C043562 |
| 2273 | 72283-72292 | Chemical | denotes | terpenoid | MESH:D013729 |
| 2287 | 72515-72519 | Gene | denotes | Mpro | Gene:8673700 |
| 2288 | 72759-72779 | Species | denotes | Tripterygium regelii | Tax:123485 |
| 2289 | 72860-72863 | Species | denotes | SAR | Tax:2698737 |
| 2290 | 72506-72514 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2291 | 72470-72480 | Chemical | denotes | terpenoids | MESH:D013729 |
| 2292 | 72557-72567 | Chemical | denotes | ferruginol | MESH:C431074 |
| 2293 | 72646-72661 | Chemical | denotes | quinone‐methide | MESH:C068040 |
| 2294 | 72662-72675 | Chemical | denotes | triterpenoids | MESH:D014315 |
| 2295 | 72676-72685 | Chemical | denotes | celastrol | MESH:C050414 |
| 2296 | 72693-72705 | Chemical | denotes | pritimererin | |
| 2297 | 72717-72726 | Chemical | denotes | tingenone | MESH:C009492 |
| 2298 | 72738-72746 | Chemical | denotes | methanol | MESH:D000432 |
| 2299 | 72917-72924 | Chemical | denotes | quinone | MESH:C004532 |
| 2307 | 73271-73275 | Gene | denotes | Mpro | Gene:8673700 |
| 2308 | 73175-73179 | Gene | denotes | Mpro | Gene:8673700 |
| 2309 | 73260-73268 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2310 | 73164-73172 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2311 | 73117-73129 | Chemical | denotes | diterpenoids | MESH:D004224 |
| 2312 | 73199-73213 | Chemical | denotes | betulinic acid | MESH:C002070 |
| 2313 | 73224-73231 | Chemical | denotes | savinin | MESH:C425325 |
| 2318 | 73413-73418 | Gene | denotes | CLpro | |
| 2319 | 73401-73409 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2320 | 73431-73438 | Chemical | denotes | sulfone | MESH:D013450 |
| 2321 | 73447-73463 | Chemical | denotes | dihydroimidazole | |
| 2326 | 73728-73732 | Gene | denotes | Mpro | Gene:8673700 |
| 2327 | 73753-73757 | Gene | denotes | Mpro | Gene:8673700 |
| 2328 | 73717-73725 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2329 | 73774-73782 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2334 | 74026-74030 | Gene | denotes | Mpro | Gene:8673700 |
| 2335 | 74015-74023 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2336 | 74352-74360 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2337 | 74214-74222 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2346 | 74704-74708 | Gene | denotes | Mpro | Gene:8673700 |
| 2347 | 74497-74501 | Gene | denotes | Mpro | Gene:8673700 |
| 2348 | 74555-74559 | Gene | denotes | Mpro | Gene:8673700 |
| 2349 | 74544-74552 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2350 | 74693-74703 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 2351 | 74628-74638 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 2352 | 74420-74429 | Chemical | denotes | serotonin | MESH:D012701 |
| 2353 | 74441-74451 | Chemical | denotes | cinanserin | MESH:D002928 |
| 2356 | 74750-74754 | Gene | denotes | Mpro | Gene:8673700 |
| 2357 | 74756-74760 | Gene | denotes | Mpro | Gene:8673700 |
| 2363 | 74842-74852 | Chemical | denotes | disulfiram | MESH:D004221 |
| 2364 | 74863-74871 | Chemical | denotes | carmofur | MESH:C017367 |
| 2365 | 74890-74897 | Chemical | denotes | ebselen | MESH:C042986 |
| 2366 | 74905-74913 | Chemical | denotes | shikonin | MESH:C016101 |
| 2367 | 74943-74948 | Chemical | denotes | PX‐12 | MESH:C412893 |
| 2374 | 75061-75065 | Gene | denotes | Mpro | Gene:8673700 |
| 2375 | 75194-75198 | Gene | denotes | Mpro | Gene:8673700 |
| 2376 | 75516-75520 | Gene | denotes | Mpro | Gene:8673700 |
| 2377 | 75505-75515 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 2378 | 75093-75099 | Chemical | denotes | Cys145 | |
| 2379 | 75365-75372 | Chemical | denotes | Ebselen | MESH:C042986 |
| 2382 | 75684-75692 | Disease | denotes | toxicity | MESH:D064420 |
| 2383 | 75872-75886 | Disease | denotes | CoV infections | MESH:D018352 |
| 2385 | 75894-75905 | Species | denotes | Coronavirus | Tax:11118 |
| 2390 | 75938-75942 | Gene | denotes | Mpro | Gene:8673700 |
| 2391 | 76145-76149 | Gene | denotes | nsp1 | Gene:10045 |
| 2392 | 76150-76154 | Gene | denotes | nsp3 | Gene:10044 |
| 2393 | 76172-76176 | Gene | denotes | nsp3 | Gene:10044 |
| 2404 | 76463-76480 | Gene | denotes | cysteine protease | Gene:1508 |
| 2405 | 76541-76547 | Chemical | denotes | Cys112 | |
| 2406 | 76548-76554 | Chemical | denotes | His273 | |
| 2407 | 76555-76561 | Chemical | denotes | Asp287 | |
| 2408 | 76563-76569 | Chemical | denotes | Cys112 | |
| 2409 | 76600-76606 | Chemical | denotes | His273 | |
| 2410 | 76631-76637 | Chemical | denotes | Asp287 | |
| 2411 | 76644-76650 | Chemical | denotes | His273 | |
| 2412 | 76686-76689 | Chemical | denotes | His | MESH:D006639 |
| 2413 | 76705-76708 | Chemical | denotes | Cys | MESH:D003545 |
| 2418 | 76779-76787 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2419 | 77002-77010 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2420 | 77234-77237 | Species | denotes | SAR | Tax:2698737 |
| 2421 | 76820-76831 | Chemical | denotes | naphthalene | MESH:C031721 |
| 2426 | 77791-77811 | Gene | denotes | papain‐like protease | |
| 2427 | 77725-77733 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2428 | 77813-77821 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2429 | 77762-77773 | Chemical | denotes | naphthalene | MESH:C031721 |
| 2432 | 77945-77950 | Chemical | denotes | amide | MESH:D000577 |
| 2433 | 77996-78005 | Chemical | denotes | benzamide | MESH:C037689 |
| 2436 | 78354-78362 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2437 | 78522-78527 | Chemical | denotes | PLpro | |
| 2440 | 79315-79323 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2441 | 79170-79200 | Chemical | denotes | m‐fluoro‐substituted benzamide | |
| 2452 | 79847-79877 | Gene | denotes | ubiquitin C‐terminal hydrolase | Gene:7345 |
| 2453 | 79880-79887 | Gene | denotes | hUCH‐L1 | Gene:7345 |
| 2454 | 79894-79901 | Gene | denotes | hUCH‐L3 | Gene:7347 |
| 2455 | 79516-79524 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2456 | 79553-79561 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 2457 | 79653-79661 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 2458 | 79707-79715 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2459 | 79771-79779 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2460 | 79792-79800 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 2461 | 79818-79823 | Species | denotes | human | Tax:9606 |
| 2464 | 79978-79998 | Gene | denotes | papain‐like protease | |
| 2465 | 80000-80008 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2470 | 80128-80136 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2471 | 80084-80094 | Chemical | denotes | thiopurine | |
| 2472 | 80105-80118 | Chemical | denotes | 6‐thioguanine | MESH:D013866 |
| 2473 | 80284-80292 | Disease | denotes | toxicity | MESH:D064420 |
| 2480 | 80442-80450 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2481 | 80564-80572 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2482 | 80644-80652 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2483 | 80858-80866 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2484 | 80411-80421 | Chemical | denotes | tanshinone | MESH:C021751 |
| 2485 | 80785-80794 | Chemical | denotes | flavonoid | MESH:D005419 |
| 2492 | 81008-81021 | Species | denotes | B. Papyrifera | Tax:172644 |
| 2493 | 81030-81038 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2494 | 81049-81057 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 2495 | 81139-81147 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2496 | 81160-81168 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 2497 | 80982-80993 | Chemical | denotes | polyphenols | MESH:D059808 |
| 2501 | 81269-81277 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2502 | 81218-81228 | Chemical | denotes | Disulfiram | MESH:D004221 |
| 2503 | 81360-81368 | Chemical | denotes | cysteine | MESH:D003545 |
| 2505 | 81457-81461 | Gene | denotes | RdRP | Gene:43740578 |
| 2507 | 81666-81670 | Gene | denotes | RdRP | Gene:43740578 |
| 2510 | 81993-81997 | Gene | denotes | RdRP | Gene:43740578 |
| 2511 | 81969-81979 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 2519 | 82527-82531 | Gene | denotes | RdRP | Gene:43740578 |
| 2520 | 82724-82732 | Species | denotes | patients | Tax:9606 |
| 2521 | 82565-82575 | Chemical | denotes | remdesivir | MESH:C000606551 |
| 2522 | 82583-82594 | Chemical | denotes | galidesivir | MESH:C517546 |
| 2523 | 82602-82611 | Chemical | denotes | ribavirin | MESH:D012254 |
| 2524 | 82619-82630 | Chemical | denotes | favipiravir | MESH:C462182 |
| 2525 | 82715-82723 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 2534 | 82957-82961 | Gene | denotes | RdRP | Gene:43740578 |
| 2535 | 82884-82888 | Gene | denotes | RdRP | Gene:43740578 |
| 2536 | 82873-82883 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 2537 | 82993-83001 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2538 | 82821-82831 | Chemical | denotes | Nucleoside | MESH:D009705 |
| 2539 | 82890-82899 | Chemical | denotes | adenosine | MESH:D000241 |
| 2540 | 82901-82910 | Chemical | denotes | guanosine | MESH:D006151 |
| 2541 | 82916-82926 | Chemical | denotes | sofosbuvir | MESH:D000069474 |
| 2552 | 83408-83411 | Gene | denotes | RTP | Gene:10397 |
| 2553 | 83465-83469 | Gene | denotes | RdRP | Gene:43740578 |
| 2554 | 83049-83059 | Chemical | denotes | Remdesivir | MESH:C000606551 |
| 2555 | 83065-83105 | Chemical | denotes | 1'‐cyano‐substitued adenine C‐nucleoside | |
| 2556 | 83209-83219 | Chemical | denotes | sofosbuvir | MESH:D000069474 |
| 2557 | 83277-83292 | Chemical | denotes | phosphoramidate | MESH:C011067 |
| 2558 | 83376-83388 | Chemical | denotes | triphosphate | MESH:C005692 |
| 2559 | 83418-83430 | Chemical | denotes | triphosphate | MESH:C005692 |
| 2560 | 83448-83455 | Chemical | denotes | adenine | MESH:D000225 |
| 2561 | 83192-83203 | Disease | denotes | hepatitis C | MESH:D006526 |
| 2572 | 83927-83930 | Gene | denotes | RTP | Gene:10397 |
| 2573 | 84254-84258 | Gene | denotes | RdRP | Gene:43740578 |
| 2574 | 83686-83690 | Gene | denotes | RdRP | Gene:43740578 |
| 2575 | 83581-83591 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 2576 | 83675-83685 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 2577 | 83553-83563 | Chemical | denotes | remdesivir | MESH:C000606551 |
| 2578 | 83696-83706 | Chemical | denotes | remdesivir | MESH:C000606551 |
| 2579 | 83707-83720 | Chemical | denotes | monophosphate | |
| 2580 | 83722-83725 | Chemical | denotes | RMP | |
| 2581 | 84043-84046 | Chemical | denotes | ATP | MESH:D000255 |
| 2596 | 84329-84337 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2597 | 84344-84352 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 2598 | 84443-84448 | Species | denotes | human | Tax:9606 |
| 2599 | 84544-84552 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2600 | 84559-84567 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 2601 | 84655-84663 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2602 | 84681-84689 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 2603 | 84697-84702 | Species | denotes | mouse | Tax:10090 |
| 2604 | 84712-84720 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2605 | 84860-84871 | Species | denotes | respiratory | Tax:12814 |
| 2606 | 84283-84293 | Chemical | denotes | Remdesivir | MESH:C000606551 |
| 2607 | 84525-84535 | Chemical | denotes | remdesivir | MESH:C000606551 |
| 2608 | 84737-84747 | Chemical | denotes | remdesivir | MESH:C000606551 |
| 2609 | 84837-84846 | Disease | denotes | infection | MESH:D007239 |
| 2623 | 85059-85063 | Gene | denotes | RdRP | Gene:43740578 |
| 2624 | 85190-85195 | Species | denotes | Ebola | Tax:1570291 |
| 2625 | 85265-85274 | Species | denotes | MERS‐CoVs | Tax:1335626 |
| 2626 | 85307-85311 | Species | denotes | CoVs | Tax:11118 |
| 2627 | 85356-85366 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 2628 | 84882-84893 | Chemical | denotes | Galidesivir | MESH:C517546 |
| 2629 | 84905-84917 | Chemical | denotes | C‐nucleoside | |
| 2630 | 84940-84949 | Chemical | denotes | adenosine | MESH:D000241 |
| 2631 | 84988-84994 | Chemical | denotes | ribose | MESH:D012266 |
| 2632 | 85006-85015 | Chemical | denotes | aza‐sugar | |
| 2633 | 85046-85055 | Chemical | denotes | adenosine | MESH:D000241 |
| 2634 | 85144-85155 | Chemical | denotes | Galidesivir | MESH:C517546 |
| 2635 | 85208-85224 | Disease | denotes | virus infections | MESH:D001102 |
| 2646 | 85788-85798 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 2647 | 85911-85919 | Species | denotes | patients | Tax:9606 |
| 2648 | 85433-85442 | Chemical | denotes | Ribavirin | MESH:D012254 |
| 2649 | 85448-85458 | Chemical | denotes | nucleoside | MESH:D009705 |
| 2650 | 85504-85513 | Chemical | denotes | guanosine | MESH:D006151 |
| 2651 | 85519-85528 | Chemical | denotes | guanosine | MESH:D006151 |
| 2652 | 85572-85577 | Chemical | denotes | amide | MESH:D000577 |
| 2653 | 85849-85858 | Chemical | denotes | ribavirin | MESH:D012254 |
| 2654 | 85740-85756 | Disease | denotes | viral infections | MESH:D001102 |
| 2655 | 85902-85910 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 2666 | 86335-86339 | Gene | denotes | RdRP | Gene:43740578 |
| 2667 | 86155-86159 | Gene | denotes | RdRP | Gene:43740578 |
| 2668 | 85998-86007 | Species | denotes | influenza | Tax:11309 |
| 2669 | 85925-85936 | Chemical | denotes | Favipiravir | MESH:C462182 |
| 2670 | 86036-86048 | Chemical | denotes | pyrazinamide | MESH:D011718 |
| 2671 | 86128-86139 | Chemical | denotes | Favipiravir | MESH:C462182 |
| 2672 | 86182-86189 | Chemical | denotes | guanine | MESH:D006147 |
| 2673 | 86243-86284 | Chemical | denotes | favipiravir‐ribofuranosyl‐5'‐triphosphate | |
| 2674 | 86396-86406 | Chemical | denotes | remdesivir | MESH:C000606551 |
| 2675 | 86511-86519 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 2684 | 86921-86925 | Gene | denotes | RdRP | Gene:43740578 |
| 2685 | 86702-86712 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 2686 | 86731-86735 | Species | denotes | CoVs | Tax:11118 |
| 2687 | 87023-87031 | Species | denotes | patients | Tax:9606 |
| 2688 | 86645-86655 | Chemical | denotes | nucleoside | MESH:D009705 |
| 2689 | 86817-86827 | Chemical | denotes | remdesivir | MESH:C000606551 |
| 2690 | 86965-86973 | Chemical | denotes | cytidine | MESH:D003562 |
| 2691 | 87014-87022 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 2695 | 87107-87111 | Gene | denotes | RdRP | Gene:43740578 |
| 2696 | 87076-87086 | Chemical | denotes | Remdesivir | MESH:C000606551 |
| 2697 | 87302-87310 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 2699 | 87747-87755 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2705 | 88056-88068 | Gene | denotes | IFN‐α and ‐β | Gene:3439 |
| 2706 | 88108-88117 | Species | denotes | MERS‐CoVs | Tax:1335626 |
| 2707 | 88044-88055 | Species | denotes | recombinant | Tax:575560 |
| 2708 | 88222-88231 | Chemical | denotes | ribavirin | MESH:D012254 |
| 2709 | 88241-88260 | Chemical | denotes | lopinavir‐ritonavir | MESH:C558899 |
| 2723 | 88702-88707 | Gene | denotes | IFN‐β | Gene:3439 |
| 2724 | 88305-88313 | Species | denotes | patients | Tax:9606 |
| 2725 | 88535-88543 | Species | denotes | patients | Tax:9606 |
| 2726 | 88754-88762 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2727 | 88839-88849 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 2728 | 88636-88641 | Species | denotes | human | Tax:9606 |
| 2729 | 88384-88393 | Chemical | denotes | ribavirin | MESH:D012254 |
| 2730 | 88414-88433 | Chemical | denotes | lopinavir‐ritonavir | MESH:C558899 |
| 2731 | 88503-88512 | Chemical | denotes | ribavirin | MESH:D012254 |
| 2732 | 88597-88606 | Chemical | denotes | ribavirin | MESH:D012254 |
| 2733 | 88687-88696 | Chemical | denotes | ribavirin | MESH:D012254 |
| 2734 | 88793-88806 | Chemical | denotes | PEGylated IFN | |
| 2735 | 88821-88830 | Chemical | denotes | ribavirin | MESH:D012254 |
| 2740 | 88983-88993 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 2741 | 88891-88903 | Chemical | denotes | Nitazoxanide | MESH:C041747 |
| 2742 | 89120-89130 | Disease | denotes | infections | MESH:D007239 |
| 2743 | 89017-89019 | CellLine | denotes | E6 | CVCL:4582 |
| 2746 | 89207-89215 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2747 | 89225-89233 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2751 | 89348-89356 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2752 | 89305-89315 | Chemical | denotes | amiodarone | MESH:D000638 |
| 2753 | 89374-89382 | Disease | denotes | infected | MESH:D007239 |
| 2755 | 89490-89502 | Chemical | denotes | Glycyrrhizin | MESH:D019695 |
| 2759 | 89776-89784 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2760 | 89626-89638 | Chemical | denotes | nitric oxide | MESH:D009569 |
| 2761 | 89703-89734 | Chemical | denotes | S‐nitroso‐N‐acetylpenicillamine | |
| 2767 | 90061-90065 | Gene | denotes | Mpro | Gene:8673700 |
| 2768 | 89882-89890 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2769 | 90036-90044 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2770 | 89955-89965 | Chemical | denotes | cinanserin | MESH:D002928 |
| 2771 | 89986-89995 | Chemical | denotes | serotonin | MESH:D012701 |
| 2776 | 90199-90203 | Gene | denotes | Mpro | Gene:8673700 |
| 2777 | 90147-90157 | Gene | denotes | calmodulin | Gene:801 |
| 2778 | 90188-90196 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2779 | 90169-90182 | Chemical | denotes | calmidazolium | MESH:C031938 |
| 2783 | 90328-90336 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 2784 | 90342-90350 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2785 | 90523-90527 | Species | denotes | CoVs | Tax:11118 |
| 2791 | 91065-91082 | Gene | denotes | Estrogen receptor | Gene:2099 |
| 2792 | 91119-91136 | Gene | denotes | Estrogen receptor | Gene:2099 |
| 2793 | 90633-90641 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2794 | 90937-90942 | Species | denotes | HIV‐1 | Tax:11676 |
| 2795 | 90926-90935 | Chemical | denotes | Lopinavir | MESH:D061466 |
| 2798 | 90576-90584 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 2799 | 90589-90597 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2801 | 92237-92245 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 2826 | 93366-93385 | Gene | denotes | estrogen receptor 1 | Gene:2099 |
| 2827 | 92590-92594 | Species | denotes | CoVs | Tax:11118 |
| 2828 | 92660-92668 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2829 | 93037-93041 | Species | denotes | CoVs | Tax:11118 |
| 2830 | 93273-93281 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2831 | 93288-93296 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 2832 | 93417-93425 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 2833 | 93430-93438 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2834 | 92684-92692 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 2835 | 92779-92783 | Species | denotes | CoVs | Tax:11118 |
| 2836 | 92905-92913 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 2837 | 92512-92525 | Chemical | denotes | cycloheximide | MESH:D003513 |
| 2838 | 92530-92540 | Chemical | denotes | anisomycin | MESH:D000841 |
| 2839 | 92623-92632 | Chemical | denotes | lopinavir | MESH:D061466 |
| 2840 | 92718-92728 | Chemical | denotes | loperamide | MESH:D008139 |
| 2841 | 92855-92862 | Chemical | denotes | emetine | MESH:D004640 |
| 2842 | 92939-92950 | Chemical | denotes | chloroquine | MESH:D002738 |
| 2843 | 92952-92970 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
| 2844 | 92976-92986 | Chemical | denotes | mefloquine | MESH:D015767 |
| 2845 | 93064-93070 | Chemical | denotes | E‐64‐D | |
| 2846 | 93136-93150 | Chemical | denotes | chlorpromazine | MESH:D002746 |
| 2847 | 93155-93170 | Chemical | denotes | triflupromazine | MESH:D014273 |
| 2848 | 93241-93252 | Chemical | denotes | gemcitabine | MESH:C056507 |
| 2849 | 93349-93359 | Chemical | denotes | Toremifene | MESH:D017312 |
| 2856 | 93566-93574 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 2857 | 93579-93587 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2858 | 93518-93526 | Chemical | denotes | imatinib | MESH:D000068877 |
| 2859 | 93531-93540 | Chemical | denotes | dasatinib | MESH:D000069439 |
| 2860 | 93591-93599 | Chemical | denotes | Imatinib | MESH:D000068877 |
| 2861 | 93641-93656 | Disease | denotes | viral infection | MESH:D001102 |
| 2873 | 94133-94137 | Gene | denotes | SKP2 | Gene:103215131 |
| 2874 | 93823-93831 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2875 | 93952-93960 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2876 | 94004-94012 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2877 | 94264-94272 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 2878 | 94313-94321 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 2879 | 93722-93733 | Chemical | denotes | Niclosamide | MESH:D009534 |
| 2880 | 94112-94123 | Chemical | denotes | niclosamide | MESH:D009534 |
| 2881 | 94162-94168 | Chemical | denotes | lysine | MESH:D008239 |
| 2882 | 94291-94302 | Chemical | denotes | Niclosamide | MESH:D009534 |
| 2883 | 94065-94067 | CellLine | denotes | E6 | CVCL:4582 |
| 2885 | 94506-94526 | Disease | denotes | SARS‐CoV‐2 infection | MESH:C000657245 |
| 2903 | 94855-94865 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 2904 | 94965-94973 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 2905 | 95293-95303 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 2906 | 95347-95355 | Species | denotes | patients | Tax:9606 |
| 2907 | 94661-94672 | Chemical | denotes | niclosamide | MESH:D009534 |
| 2908 | 94683-94694 | Chemical | denotes | ciclesonide | MESH:C120481 |
| 2909 | 94794-94805 | Chemical | denotes | Niclosamide | MESH:D009534 |
| 2910 | 94897-94908 | Chemical | denotes | niclosamide | MESH:D009534 |
| 2911 | 94980-94991 | Chemical | denotes | Ciclesonide | MESH:C120481 |
| 2912 | 95108-95119 | Chemical | denotes | niclosamide | MESH:D009534 |
| 2913 | 95129-95137 | Chemical | denotes | cortisol | MESH:D006854 |
| 2914 | 95244-95255 | Chemical | denotes | ciclesonide | MESH:C120481 |
| 2915 | 95634-95645 | Chemical | denotes | ciclesonide | MESH:C120481 |
| 2916 | 95163-95169 | Disease | denotes | asthma | MESH:D001249 |
| 2917 | 95174-95191 | Disease | denotes | allergic rhinitis | MESH:D065631 |
| 2918 | 95338-95346 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 2919 | 95699-95707 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 2926 | 95815-95825 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 2927 | 95871-95876 | Species | denotes | human | Tax:9606 |
| 2928 | 96039-96047 | Species | denotes | patients | Tax:9606 |
| 2929 | 95718-95730 | Chemical | denotes | Azithromycin | MESH:D017963 |
| 2930 | 95779-95797 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
| 2931 | 96030-96038 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 2937 | 96111-96121 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 2938 | 96089-96099 | Chemical | denotes | colchicine | MESH:D003078 |
| 2939 | 96177-96189 | Disease | denotes | inflammation | MESH:D007249 |
| 2940 | 96194-96212 | Disease | denotes | lung complications | MESH:D008171 |
| 2941 | 96221-96229 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 2948 | 96241-96251 | Chemical | denotes | Famotidine | MESH:D015738 |
| 2949 | 96429-96439 | Chemical | denotes | Cimetidine | MESH:D002927 |
| 2950 | 96295-96303 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 2951 | 96371-96377 | Disease | denotes | ulcers | MESH:D014456 |
| 2952 | 96382-96413 | Disease | denotes | gastroesophageal reflux disease | MESH:D005764 |
| 2953 | 96505-96513 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 2956 | 96515-96527 | Chemical | denotes | Dipyridamole | MESH:D004176 |
| 2957 | 96560-96568 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 2962 | 96708-96718 | Chemical | denotes | Sildenafil | MESH:D000068677 |
| 2963 | 96749-96757 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 2964 | 96854-96874 | Disease | denotes | erectile dysfunction | MESH:D007172 |
| 2965 | 96879-96910 | Disease | denotes | pulmonary arterial hypertension | MESH:D000081029 |
| 2972 | 96912-96923 | Chemical | denotes | Fenofibrate | MESH:D011345 |
| 2973 | 96928-96939 | Chemical | denotes | bezafibrate | MESH:D001629 |
| 2974 | 96991-97002 | Chemical | denotes | Fenofibrate | MESH:D011345 |
| 2975 | 97014-97019 | Chemical | denotes | lipid | MESH:D008055 |
| 2976 | 97098-97103 | Chemical | denotes | lipid | MESH:D008055 |
| 2977 | 96981-96989 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 2996 | 97209-97217 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2997 | 97445-97455 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 2998 | 97764-97774 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 2999 | 97977-97987 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 3000 | 98228-98238 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 3001 | 98309-98317 | Species | denotes | patients | Tax:9606 |
| 3002 | 98343-98353 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 3003 | 97147-97157 | Chemical | denotes | nelfinavir | MESH:D019888 |
| 3004 | 97395-97405 | Chemical | denotes | nelfinavir | MESH:D019888 |
| 3005 | 97582-97592 | Chemical | denotes | nelfinavir | MESH:D019888 |
| 3006 | 97792-97802 | Chemical | denotes | amprenavir | MESH:C095108 |
| 3007 | 97846-97855 | Chemical | denotes | darunavir | MESH:D000069454 |
| 3008 | 97903-97912 | Chemical | denotes | indinavir | MESH:D019469 |
| 3009 | 97956-97966 | Chemical | denotes | Tipranavir | MESH:C107201 |
| 3010 | 98259-98268 | Chemical | denotes | Lopinavir | MESH:D061466 |
| 3011 | 97329-97349 | Disease | denotes | SARS‐CoV‐1 infection | MESH:C000657245 |
| 3012 | 97727-97735 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 3013 | 98300-98308 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 3021 | 98664-98672 | Species | denotes | SARS‐CoV | Tax:694009 |
| 3022 | 98676-98684 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 3023 | 98690-98699 | Species | denotes | HCoV‐229E | Tax:11137 |
| 3024 | 98484-98495 | Chemical | denotes | chloroquine | MESH:D002738 |
| 3025 | 98501-98515 | Chemical | denotes | chlorpromazine | MESH:D002746 |
| 3026 | 98522-98532 | Chemical | denotes | loperamide | MESH:D008139 |
| 3027 | 98544-98553 | Chemical | denotes | lopinavir | MESH:D061466 |
| 3031 | 98898-98906 | Species | denotes | SARS‐CoV | Tax:694009 |
| 3032 | 98876-98887 | Species | denotes | respiratory | Tax:12814 |
| 3033 | 98837-98856 | Disease | denotes | SARS‐CoV infections | MESH:C000657245 |
| 3038 | 98990-99000 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 3039 | 99087-99095 | Species | denotes | patients | Tax:9606 |
| 3040 | 98954-98965 | Chemical | denotes | Chloroquine | MESH:D002738 |
| 3041 | 99078-99086 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 3050 | 99246-99254 | Species | denotes | SARS‐CoV | Tax:694009 |
| 3051 | 99258-99266 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 3052 | 99272-99281 | Species | denotes | HCoV‐229E | Tax:11137 |
| 3053 | 99520-99528 | Species | denotes | SARS‐CoV | Tax:694009 |
| 3054 | 99540-99548 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 3055 | 99199-99213 | Chemical | denotes | Chlorpromazine | MESH:D002746 |
| 3056 | 99321-99334 | Disease | denotes | schizophrenia | MESH:D012559 |
| 3057 | 99641-99649 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 3063 | 99748-99756 | Species | denotes | SARS‐CoV | Tax:694009 |
| 3064 | 99760-99768 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 3065 | 99774-99783 | Species | denotes | HCoV‐229E | Tax:11137 |
| 3066 | 99651-99661 | Chemical | denotes | Loperamide | MESH:D008139 |
| 3067 | 99704-99712 | Disease | denotes | diarrhea | MESH:D003967 |
| 3071 | 99875-99879 | Gene | denotes | Mpro | Gene:8673700 |
| 3072 | 99864-99872 | Species | denotes | SARS‐CoV | Tax:694009 |
| 3073 | 99785-99794 | Chemical | denotes | Lopinavir | MESH:D061466 |
| 3082 | 100014-100022 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 3083 | 100521-100525 | Species | denotes | CoVs | Tax:11118 |
| 3084 | 100534-100542 | Species | denotes | SARS‐CoV | Tax:694009 |
| 3085 | 100561-100570 | Species | denotes | HCoV‐229E | Tax:11137 |
| 3086 | 100591-100595 | Species | denotes | FIPV | Tax:11135 |
| 3087 | 100295-100303 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 3088 | 100223-100234 | Chemical | denotes | Saracatinib | MESH:C515233 |
| 3089 | 100425-100444 | Disease | denotes | malignant neoplasms | MESH:D009369 |
| 3093 | 100736-100746 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 3094 | 100979-100989 | Disease | denotes | infections | MESH:D007239 |
| 3095 | 101150-101158 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 3100 | 101247-101258 | Species | denotes | coronavirus | Tax:11118 |
| 3101 | 101288-101291 | Species | denotes | CoV | Tax:11118 |
| 3102 | 101534-101542 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 3103 | 101603-101611 | Disease | denotes | covid-19 | MESH:C000657245 |
| 3107 | 102403-102408 | Gene | denotes | COX‐2 | Gene:4513 |
| 3108 | 102181-102191 | Chemical | denotes | Remdesivir | MESH:C000606551 |
| 3109 | 102312-102331 | Chemical | denotes | Lopinavir/ritonavir | MESH:C558899 |
| 3111 | 103683-103691 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 3122 | 104014-104018 | Gene | denotes | RdRP | Gene:43740578 |
| 3123 | 104231-104235 | Gene | denotes | ACE2 | Gene:59272 |
| 3124 | 103998-104002 | Gene | denotes | Mpro | Gene:8673700 |
| 3125 | 104071-104076 | Species | denotes | human | Tax:9606 |
| 3126 | 104087-104091 | Species | denotes | CoVs | Tax:11118 |
| 3127 | 104125-104133 | Species | denotes | SARS‐CoV | Tax:694009 |
| 3128 | 104140-104150 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 3129 | 104215-104220 | Species | denotes | human | Tax:9606 |
| 3130 | 104422-104430 | Species | denotes | SARS‐CoV | Tax:694009 |
| 3131 | 104180-104189 | Disease | denotes | infection | MESH:D007239 |
| 3133 | 104633-104637 | Gene | denotes | ACE2 | Gene:59272 |
| 3147 | 105073-105077 | Gene | denotes | ACE2 | Gene:59272 |
| 3148 | 105181-105187 | Gene | denotes | GRP‐78 | Gene:3309 |
| 3149 | 105413-105419 | Gene | denotes | GRP‐78 | Gene:3309 |
| 3150 | 105572-105578 | Gene | denotes | GRP‐78 | Gene:3309 |
| 3151 | 105349-105350 | Gene | denotes | S | Gene:43740568 |
| 3152 | 105067-105068 | Gene | denotes | S | Gene:43740568 |
| 3153 | 105056-105066 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 3154 | 105287-105291 | Species | denotes | CoVs | Tax:11118 |
| 3155 | 105296-105304 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 3156 | 105338-105348 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 3157 | 105432-105440 | Species | denotes | patients | Tax:9606 |
| 3158 | 105151-105158 | Chemical | denotes | glucose | MESH:D005947 |
| 3159 | 105423-105431 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 3165 | 105784-105788 | Gene | denotes | Mpro | Gene:8673700 |
| 3166 | 106109-106113 | Gene | denotes | Mpro | Gene:8673700 |
| 3167 | 106146-106150 | Gene | denotes | Mpro | Gene:8673700 |
| 3168 | 105996-106000 | Species | denotes | CoVs | Tax:11118 |
| 3169 | 106080-106085 | Species | denotes | human | Tax:9606 |
| 3176 | 106707-106717 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 3177 | 106609-106629 | Chemical | denotes | (hydroxy)chloroquine | MESH:D006886 |
| 3178 | 106631-106642 | Chemical | denotes | favipiravir | MESH:C462182 |
| 3179 | 106644-106653 | Chemical | denotes | ribavirin | MESH:D012254 |
| 3180 | 106658-106668 | Chemical | denotes | umifenovir | MESH:C086979 |
| 3181 | 106340-106348 | Disease | denotes | toxicity | MESH:D064420 |
| 3186 | 107386-107394 | Species | denotes | patients | Tax:9606 |
| 3187 | 107607-107615 | Species | denotes | patients | Tax:9606 |
| 3188 | 107132-107140 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 3189 | 107598-107606 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 3196 | 107896-107907 | Species | denotes | coronavirus | Tax:11118 |
| 3197 | 107990-107995 | Species | denotes | Human | Tax:9606 |
| 3198 | 108006-108010 | Species | denotes | CoVs | Tax:11118 |
| 3199 | 108229-108235 | Species | denotes | humans | Tax:9606 |
| 3200 | 108384-108388 | Species | denotes | CoVs | Tax:11118 |
| 3201 | 108493-108498 | Species | denotes | human | Tax:9606 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-44 | Sentence | denotes | The recent outbreaks of human coronaviruses: |
| T2 | 45-78 | Sentence | denotes | A medicinal chemistry perspective |
| T3 | 79-95 | Sentence | denotes | PILLAIYAR et al. |
| T4 | 97-105 | Sentence | denotes | Abstract |
| T5 | 106-114 | Sentence | denotes | Abstract |
| T6 | 115-167 | Sentence | denotes | Coronaviruses (CoVs) infect both humans and animals. |
| T7 | 168-290 | Sentence | denotes | In humans, CoVs can cause respiratory, kidney, heart, brain, and intestinal infections that can range from mild to lethal. |
| T8 | 291-521 | Sentence | denotes | Since the start of the 21st century, three β‐coronaviruses have crossed the species barrier to infect humans: severe‐acute respiratory syndrome (SARS)‐CoV‐1, Middle East respiratory syndrome (MERS)‐CoV, and SARS‐CoV‐2 (2019‐nCoV). |
| T9 | 522-600 | Sentence | denotes | These viruses are dangerous and can easily be transmitted from human to human. |
| T10 | 601-676 | Sentence | denotes | Therefore, the development of anticoronaviral therapies is urgently needed. |
| T11 | 677-762 | Sentence | denotes | However, to date, no approved vaccines or drugs against CoV infections are available. |
| T12 | 763-988 | Sentence | denotes | In this review, we focus on the medicinal chemistry efforts toward the development of antiviral agents against SARS‐CoV‐1, MERS‐CoV, SARS‐CoV‐2, targeting biochemical events important for viral replication and its life cycle. |
| T13 | 989-1220 | Sentence | denotes | These targets include the spike glycoprotein and its host‐receptors for viral entry, proteases that are essential for cleaving polyproteins to produce functional proteins, and RNA‐dependent RNA polymerase for viral RNA replication. |
| T14 | 1222-1235 | Sentence | denotes | Abbreviations |
| T15 | 1236-1259 | Sentence | denotes | 3CLpro 3C‐like protease |
| T16 | 1260-1293 | Sentence | denotes | ACE angiotensin‐converting enzyme |
| T17 | 1294-1312 | Sentence | denotes | ACEi ACE‐inhibitor |
| T18 | 1313-1336 | Sentence | denotes | ADA adenosine deaminase |
| T19 | 1337-1352 | Sentence | denotes | Ang angiotensin |
| T20 | 1353-1385 | Sentence | denotes | ARB angiotensin receptor blocker |
| T21 | 1386-1426 | Sentence | denotes | ARDS acute respiratory distress syndrome |
| T22 | 1427-1444 | Sentence | denotes | CoV coronaviruses |
| T23 | 1445-1469 | Sentence | denotes | DPP dipeptidyl peptidase |
| T24 | 1470-1518 | Sentence | denotes | ESI‐MS electrospray ionization mass spectrometry |
| T25 | 1519-1551 | Sentence | denotes | HKU1 HCoV‐Hong Kong University 1 |
| T26 | 1552-1569 | Sentence | denotes | HR heptad repeats |
| T27 | 1570-1599 | Sentence | denotes | HTS high throughput screening |
| T28 | 1600-1651 | Sentence | denotes | ICTV International Committee on Taxonomy of Viruses |
| T29 | 1652-1666 | Sentence | denotes | IL interleukin |
| T30 | 1667-1681 | Sentence | denotes | kDa kiloDalton |
| T31 | 1682-1719 | Sentence | denotes | MERS Middle East respiratory syndrome |
| T32 | 1720-1748 | Sentence | denotes | MHV2 mouse hepatitis virus‐2 |
| T33 | 1749-1767 | Sentence | denotes | Mpro main protease |
| T34 | 1768-1801 | Sentence | denotes | NIH National Institutes of Health |
| T35 | 1802-1824 | Sentence | denotes | ORF open reading frame |
| T36 | 1825-1854 | Sentence | denotes | PCR polymerase chain reaction |
| T37 | 1855-1881 | Sentence | denotes | PLpro papain‐like protease |
| T38 | 1882-1896 | Sentence | denotes | pp polyprotein |
| T39 | 1897-1924 | Sentence | denotes | RBD receptor‐binding domain |
| T40 | 1925-1958 | Sentence | denotes | RdRP RNA‐dependent RNA polymerase |
| T41 | 1959-1997 | Sentence | denotes | SARS severe‐acute respiratory syndrome |
| T42 | 1998-2026 | Sentence | denotes | TACE TNF‐α converting enzyme |
| T43 | 2027-2067 | Sentence | denotes | TGEV transmissible gastroenteritis virus |
| T44 | 2068-2104 | Sentence | denotes | TMPRSS transmembrane serine protease |
| T45 | 2106-2121 | Sentence | denotes | 1 INTRODUCTION |
| T46 | 2122-2169 | Sentence | denotes | Coronaviruses (CoVs) infect humans and animals. |
| T47 | 2170-2284 | Sentence | denotes | In humans, CoVs cause primarily multiple respiratory and intestinal infections that can range from mild to lethal. |
| T48 | 2285-2439 | Sentence | denotes | 1 , 2 , 3 According to the International Committee on Taxonomy of Viruses (ICTV), CoVs constitute the family Coronaviridae under the order Nidovirales. |
| T49 | 2440-2610 | Sentence | denotes | Coronaviridae comprise two subfamilies, Torovirinae and Coronavirinae, the latter being further divided into four main genera: α‐, β‐, γ‐, and δ‐coronaviruses (Figure 1). |
| T50 | 2611-2843 | Sentence | denotes | 4 The history of human CoVs began in the 1930s, but only in the 1960s, the first human CoVs were identified in patients with mild respiratory infections, which were later named HCoV‐229E and HCoV‐OC43, belonging to α‐coronaviruses. |
| T51 | 2844-2994 | Sentence | denotes | 5 , 6 , 7 Since then, virologists have discovered new viruses, studying their infection mechanisms, as well as their replication, and pathogenesis. |
| T52 | 2995-3296 | Sentence | denotes | This led to the identification of five novel CoVs belonging to β‐coronaviruses that have crossed the species barrier to infect humans: HCoV‐Hong Kong University 1 (HKU1), HCoV‐NL63, severe‐acute respiratory syndrome (SARS)‐CoV‐1, Middle East respiratory syndrome (MERS)‐CoV, and SARS‐CoV‐2 (COVID‐19). |
| T53 | 3297-3431 | Sentence | denotes | Figure 1 Schematic representation of the taxonomy of Coronaviridae (according to the International Committee on Taxonomy of Viruses). |
| T54 | 3432-3725 | Sentence | denotes | The seven human‐infecting coronaviruses belong to the α‐ or β‐coronavirus genus (highly infectious pathogens are highlighted red) [Color figure can be viewed at wileyonlinelibrary.com] The three last‐mentioned viruses are extremely dangerous because of their rapid transmission between humans. |
| T55 | 3726-3833 | Sentence | denotes | SARS‐CoV‐1, which emerged in 2002, affected 8096 in 32 countries, 774 of whom died (fatality rate 10%–15%). |
| T56 | 3834-3968 | Sentence | denotes | 8 MERS‐CoV, which appeared in 2012, affected a total of 1841 individuals, 652 of whom died with the mortality rate of ~35% worldwide. |
| T57 | 3969-3970 | Sentence | denotes | 9 |
| T58 | 3971-4165 | Sentence | denotes | The new coronavirus, known as SARS‐CoV‐2 or 2019‐nCoV has been identified as an etiological agent for the current epidemic with a contagious pneumonia‐like illness, spreading incredibly rapidly. |
| T59 | 4166-4309 | Sentence | denotes | As of July 15, 2020, the outbreak of SARS‐CoV‐2 has claimed more than 573 752 lives and infected more than 13 119 239 people around the planet. |
| T60 | 4310-4454 | Sentence | denotes | 10 Public life has come to a halt, as many governments impose social distancing strategies and lockdown to prevent further spread of the virus. |
| T61 | 4455-4600 | Sentence | denotes | To date, no targeted therapeutics or vaccines are approved, and effective treatment options against any human‐infecting CoVs remain very limited. |
| T62 | 4602-4664 | Sentence | denotes | 1.1 Infection cycle of human CoVs and their druggable targets |
| T63 | 4665-4743 | Sentence | denotes | Human‐infecting CoVs belonging to the α‐ and β‐CoV genera infect only mammals. |
| T64 | 4744-4973 | Sentence | denotes | According to the sequence database, all human CoVs have animal origins; HCoV‐NL63, HCoV‐229E, SARS‐CoV‐1, SARS‐CoV‐2, and MERS‐CoV are suggested to have originated from bats; HCoV‐OC43 and HKU1‐CoV likely originated from rodents. |
| T65 | 4974-4982 | Sentence | denotes | 11 , 12 |
| T66 | 4983-5142 | Sentence | denotes | CoVs are enveloped, single‐stranded, positive‐sense RNA viruses featuring the largest viral RNA genomes known to date, ranging roughly from 26 to 32 kilobases. |
| T67 | 5143-5195 | Sentence | denotes | The SARS‐CoV‐2 genome comprises ~30 000 nucleotides. |
| T68 | 5196-5338 | Sentence | denotes | 13 For the virus to spread, the information of its structural and functional proteins must be replicated and packed into new virus particles. |
| T69 | 5339-5514 | Sentence | denotes | Since the virus lacks the necessary infrastructure for this process, it is entirely dependent on its host organism to translate its RNA into proteins and make more RNA copies. |
| T70 | 5515-5625 | Sentence | denotes | To infect its desired host cell, the virus uses its many spike (S) glycoproteins protruding from its membrane. |
| T71 | 5626-5757 | Sentence | denotes | 13 In general, the life cycle of CoVs can be classified into four main steps, including entry, replication, assembly, and release. |
| T72 | 5758-5820 | Sentence | denotes | The infection cycle of a CoV (Figure 2) begins with its entry. |
| T73 | 5821-5905 | Sentence | denotes | Using the S glycoprotein, it attaches itself to a surface receptor of the host cell. |
| T74 | 5906-5987 | Sentence | denotes | The host cell receptor and its distribution determine which tissues get infected. |
| T75 | 5988-6071 | Sentence | denotes | The specificity of the S protein to a particular receptor influences viral tropism. |
| T76 | 6072-6387 | Sentence | denotes | CoVs use different human receptors as points of entry: SARS‐CoV‐1, SARS‐CoV‐2, and HCoV‐NL63 use angiotensin‐converting enzyme 2 (ACE2); 14 , 15 , 16 MERS‐CoV uses dipeptidyl peptidase‐4 (DPP4); 17 CoV‐22E uses aminopeptidase N; 18 and HCoV‐OC43 as well as HCoV‐HKUI use O‐acetylated sialic acid (see Table 1). |
| T77 | 6388-6396 | Sentence | denotes | 19 , 20 |
| T78 | 6397-6465 | Sentence | denotes | Figure 2 Infection cycle of coronaviruses, for example, SARS‐CoV‐2. |
| T79 | 6466-6577 | Sentence | denotes | The figure was adapted with permission from Invivogen (https://www.invivogen.com/spotlight-covid-19-infection). |
| T80 | 6578-6692 | Sentence | denotes | SARS‐CoV‐2, severe acute respiratory syndrome coronavirus 2 [Color figure can be viewed at wileyonlinelibrary.com] |
| T81 | 6693-6798 | Sentence | denotes | Table 1 Classification, discovery, cellular receptor, and natural intermediate host of the coronaviruses |
| T82 | 6799-6872 | Sentence | denotes | HCoV genera Coronaviruses Discovery Cellular receptor Natural host(s) |
| T83 | 6873-6942 | Sentence | denotes | α‐Coronaviruses HCoV‐229E 1966 Human aminopeptidase N (CD13) Bats |
| T84 | 6943-6983 | Sentence | denotes | HCoV‐NL63 2004 ACE2 Palm civets, bats |
| T85 | 6984-7052 | Sentence | denotes | β‐Coronaviruses HCoV‐OC43 1967 9‐O‐Acetylated sialic acid Cattle |
| T86 | 7053-7102 | Sentence | denotes | HCoV‐HKU1 2005 9‐O‐Acetylated sialic acid Mice |
| T87 | 7103-7138 | Sentence | denotes | SARS‐CoV‐1 2003 ACE2 Palm civets |
| T88 | 7139-7173 | Sentence | denotes | MERS‐CoV 2012 DPP4 Bats, camels |
| T89 | 7174-7207 | Sentence | denotes | SARS‐CoV‐2 2019 ACE2 Bats, (?) |
| T90 | 7208-7334 | Sentence | denotes | Note: ? indicate other possible hosts of SARS‐CoV‐2, besides bats ‐ if they exist ‐ have not been conclusively identified yet. |
| T91 | 7335-7358 | Sentence | denotes | John Wiley & Sons, Ltd. |
| T92 | 7359-7483 | Sentence | denotes | This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. |
| T93 | 7484-7666 | Sentence | denotes | It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency. |
| T94 | 7667-7798 | Sentence | denotes | When the spike protein attaches to its host cellular receptor, it is cleaved into two parts (S1 and S2) by extracellular proteases. |
| T95 | 7799-7927 | Sentence | denotes | While S1 remains attached to its target, S2 is further cleaved by the host cell's own transmembrane serine protease 2 (TMPRSS2). |
| T96 | 7928-8012 | Sentence | denotes | This process induces the fusion of the viral membrane with the host cell's membrane. |
| T97 | 8013-8015 | Sentence | denotes | 15 |
| T98 | 8016-8108 | Sentence | denotes | Upon fusion, the contents of the virus particle are released into the host cell's cytoplasm. |
| T99 | 8109-8286 | Sentence | denotes | The virus's genomic positive‐sense RNA, which comprises two overlapping open reading frames (ORFs), ORF1a and ORF1b, is quickly translated into two polyproteins, pp1a and pp1ab. |
| T100 | 8287-8416 | Sentence | denotes | These proteins are the so‐called replicase‐transcriptase‐complex, because of their role in replication and further transcription. |
| T101 | 8417-8640 | Sentence | denotes | The newly formed polyproteins are immediately autocatalytically proteolyzed into smaller proteins by two viral proteases, 3C‐like protease (3CLpro), otherwise known as main protease (Mpro), and papain‐like protease (PLpro). |
| T102 | 8641-8649 | Sentence | denotes | 21 , 22 |
| T103 | 8650-8941 | Sentence | denotes | The cleavage products include 16 nonstructural proteins (nsp) like the RNA‐dependent RNA polymerase (RdRP) that facilitates the production of antisense RNA, as well as 4 structural proteins like the S glycoprotein, envelope (E) proteins, membrane proteins (M), and nucleocapsid (N) proteins. |
| T104 | 8942-9199 | Sentence | denotes | 21 , 22 , 23 Newly generated antisense RNA is used as a template for new copies of viral positive‐sense RNA as well as for the production of differently sized subgenomic mRNAs, which can be translated into new viral proteins at the endoplasmic reticulum. |
| T105 | 9200-9366 | Sentence | denotes | Finally, proteins and genomic RNA are assembled, packed into vesicles in the Golgi apparatus and exocytosed to the outside to repeat the process in surrounding cells. |
| T106 | 9367-9369 | Sentence | denotes | 23 |
| T107 | 9370-9489 | Sentence | denotes | This process does not pass unnoticed by the host organism, as infected cells present viral structures on their surface. |
| T108 | 9490-9668 | Sentence | denotes | As a response, many defensive pathways are initiated, such as the production of different cytokines and chemokines like interleukin 1 (IL‐1), IL‐6, IL‐8, IL‐21, TNF‐β, and MCP‐1. |
| T109 | 9669-9782 | Sentence | denotes | The release of these mediators and their effector cells activate inflammatory mechanisms to destroy the intruder. |
| T110 | 9783-9785 | Sentence | denotes | 24 |
| T111 | 9786-9919 | Sentence | denotes | The interruption of any stage of the viral life cycle can become an important therapeutic approach for treating CoV‐related diseases. |
| T112 | 9920-10099 | Sentence | denotes | A recent SARS‐CoV‐2‐human protein‐protein interaction analysis showed that SARS‐CoV‐2 contains approximately 66 druggable proteins, each of which has several ligand binding sites. |
| T113 | 10100-10215 | Sentence | denotes | 25 The most interesting coronavirus proteins are the S glycoprotein, proteases Mpro and PLpro, RdRP, and helicase. |
| T114 | 10216-10368 | Sentence | denotes | In this review, we highlight these targets with potential therapeutic development against the highly dangerous pathogens SARS‐CoV‐1 and 2, and MERS‐CoV. |
| T115 | 10369-10483 | Sentence | denotes | Medicinal chemistry efforts toward the evolution of molecules with drug‐like properties is additionally discussed. |
| T116 | 10484-10677 | Sentence | denotes | In addition, broad‐spectrum antivirals targeting the major viruses are reviewed in detail, since they represent a highly promising strategy for treating these often fatal respiratory illnesses. |
| T117 | 10679-10704 | Sentence | denotes | 2 VIRUS ENTRY INHIBITORS |
| T118 | 10705-10882 | Sentence | denotes | Binding of spike protein (S) to its receptor represents the host's first confrontation with the virus and its life cycle, thus providing prophylactic intervention opportunities. |
| T119 | 10883-11022 | Sentence | denotes | The genome of SARS‐CoV‐2 has been recently determined to have an 80% identity to that of SARS‐CoV‐1 and 96% identity to the bat‐CoV RaTG13. |
| T120 | 11023-11143 | Sentence | denotes | 26 The SARS‐CoV‐2 S protein shows nucleotide sequence identities of 75% or less to all other previously described CoVs. |
| T121 | 11144-11240 | Sentence | denotes | However, again, the new SARS‐CoV‐2 S protein shares a 93.1% identity to the S protein of RaTG13. |
| T122 | 11241-11520 | Sentence | denotes | SARS‐CoV‐2 spike (S) recognizes, with its receptor‐binding domain (RBD), the cellular ACE2 receptor with high affinity (K d, 14.7 nM) 27 as judged by surface plasmin resonance spectrometry; and intervention at the RBD‐ACE2 interface can potentially disrupt infection efficiency. |
| T123 | 11521-11633 | Sentence | denotes | It was observed that the RBDs of the SARS‐CoV‐2‐ACE2 and SARS‐CoV‐1‐ACE2 complexes are quite similar (Figure 3). |
| T124 | 11634-11636 | Sentence | denotes | 29 |
| T125 | 11637-11809 | Sentence | denotes | Figure 3 Comparison of the SARS‐CoV‐2 S and SARS‐CoV‐1 S structures: ribbon diagrams of the (A) SARS‐CoV‐2 S and (D) SARS‐CoV‐1 S [PDB 6NB6] ectodomain cryo‐EM structures. |
| T126 | 11810-11863 | Sentence | denotes | S1 subunits of (B) SARS‐CoV‐2 S and (E) SARS‐CoV‐1 S. |
| T127 | 11864-11917 | Sentence | denotes | S2 subunits of (C) SARS‐CoV‐2 S and (F) SARS‐CoV‐1 S. |
| T128 | 11918-12114 | Sentence | denotes | 28 cryo‐EM, cryogenic electron microscopy; SARS‐CoV‐2, severe acute respiratory syndrome coronavirus 2 [Color figure can be viewed at wileyonlinelibrary.com] As mentioned previously, Zhang et al. |
| T129 | 12115-12281 | Sentence | denotes | 30 determined the full‐length genome sequence of SARS‐CoV‐2 and revealed that the virus is remarkably similar (89.1% sequence identity) to a group of SARS‐like CoVs. |
| T130 | 12282-12308 | Sentence | denotes | Simultaneously, Shi et al. |
| T131 | 12309-12498 | Sentence | denotes | 26 reported that SARS‐CoV‐2 shares 96% sequence identity at a whole‐genome level with a bat coronavirus—and importantly, like SARS‐CoV‐1, SARS‐CoV‐2 utilizes ACE2 receptor for viral entry. |
| T132 | 12499-12690 | Sentence | denotes | Recently, Yan et al. solved the cryo‐EM structure of full‐length human ACE2 bound to the RBD of SARS‐CoV‐2, providing important structural information for therapeutic intervention strategies. |
| T133 | 12691-12693 | Sentence | denotes | 29 |
| T134 | 12694-12798 | Sentence | denotes | The sequence identity of the spike protein between SARS‐CoV‐1 (1273 aa) and SARS‐CoV‐2 (1253 aa) is 76%. |
| T135 | 12799-12844 | Sentence | denotes | The spike protein has two regions, S1 and S2. |
| T136 | 12845-12935 | Sentence | denotes | The S1 region of the SARS‐CoV‐1 has a RBD that forms high‐affinity interactions with ACE2. |
| T137 | 12936-13038 | Sentence | denotes | The prevailing understanding is that SARS‐CoV‐2 employs this RBD to enter its human host cell as well. |
| T138 | 13039-13109 | Sentence | denotes | Aligning the two different RBDs revealed a sequence identity of 73.5%. |
| T139 | 13110-13222 | Sentence | denotes | However, many nonconserved mutations that interact directly with ACE2 are located in the two structural regions. |
| T140 | 13223-13414 | Sentence | denotes | 31 And both crystal and cryo‐EM structures of the SARS‐CoV‐1 spike‐ACE2 complex have shown that merely residues of regions 1 and 2 form hydrogen bonds and hydrophobic interactions with ACE2. |
| T141 | 13415-13528 | Sentence | denotes | The mutations in these two regions of SARS‐CoV‐2 will, therefore, likely reduce the number of those interactions. |
| T142 | 13529-13531 | Sentence | denotes | 32 |
| T143 | 13532-13639 | Sentence | denotes | Studies also have shown that the RdRP, and the Mpro are highly conserved between SARS‐CoV‐2 and SARS‐CoV‐1. |
| T144 | 13640-13774 | Sentence | denotes | 33 , 34 Therefore, it is widely accepted that SARS‐CoV‐2 behaves similarly to SARS‐CoV‐1 with regard to viral entry and replication. |
| T145 | 13775-13951 | Sentence | denotes | Since the general genomic layout and replication kinetics are so conserved among MERS, SARS‐1, and SARS‐2 CoVs, investigating inhibitors of common structures is a logical step. |
| T146 | 13952-14134 | Sentence | denotes | The inhibitory strength against viral enzyme was expressed as IC50, which is the concentration of the inhibitor needed to inhibit half of the enzyme activity in the tested condition. |
| T147 | 14135-14204 | Sentence | denotes | The K i value is reflective of ligand‐binding affinity to the enzyme. |
| T148 | 14205-14367 | Sentence | denotes | The inhibitory activity for cell‐based bioassays is expressed as EC50, which is a half maximal effective concentration required to induce the biological response. |
| T149 | 14368-14536 | Sentence | denotes | The warhead group means a “reactive group” of the inhibitors that can form both covalent and noncovalent interactions with amino acids in the active site of the enzyme. |
| T150 | 14538-14560 | Sentence | denotes | 2.1 Targeting the RBD |
| T151 | 14561-14673 | Sentence | denotes | Structural investigations of the RBD‐ACE2 complex provided information about essential residues for viral entry. |
| T152 | 14674-14687 | Sentence | denotes | Hsiang et al. |
| T153 | 14688-14827 | Sentence | denotes | 35 reported a number of peptides that significantly blocked the interaction of the S protein with ACE2 with IC50 values as low as 1.88 nM. |
| T154 | 14828-14929 | Sentence | denotes | Michael et al. found charged residues between positions 22 and 57 crucial for SARS‐CoV‐1 viral entry. |
| T155 | 14930-15063 | Sentence | denotes | Based on this, they designed peptides P4 (IC50, 50 µM) and P5 (IC50, 6.0 µM) with significant inhibitory activity against SARS‐CoV‐1. |
| T156 | 15064-15332 | Sentence | denotes | The antiviral activity was further improved when they introduced the glycine binding linkage of peptide P4 (residues 22–47) with an ACE2‐derived peptide (residues 351–357) against a SARS‐CoV‐1 pseudovirus with an IC50 of 100 nM and devoid of cytotoxicity up to 200 µM. |
| T157 | 15333-15420 | Sentence | denotes | 36 It is worth highlighting that a similar strategy could work for the new SARS‐CoV‐2. |
| T158 | 15421-15558 | Sentence | denotes | The recently solved cryo‐EM structure of SARS‐CoV‐2 in complex with human ACE2 can provide a structural rationale for the peptide design. |
| T159 | 15559-15561 | Sentence | denotes | 29 |
| T160 | 15562-15735 | Sentence | denotes | For viral entry, MERS‐CoV uses its spike protein (S) to interact with the host‐receptor DPP4, 37 , 38 , 39 also known as adenosine deaminase‐complexing protein‐2 or CD26. |
| T161 | 15736-15811 | Sentence | denotes | 37 MERS‐CoV was also the first virus reported to use this particular path. |
| T162 | 15812-15960 | Sentence | denotes | 35 , 37 DPP4 is a type II transmembrane glycoprotein, that forms homodimers on the cell surface, and it is involved in the cleavage of dipeptides. |
| T163 | 15961-16076 | Sentence | denotes | 37 , 40 In humans, DPP4 is predominantly found on the bronchial epithelial and alveolar cells in the lower lungs. |
| T164 | 16077-16085 | Sentence | denotes | 40 , 41 |
| T165 | 16086-16236 | Sentence | denotes | MERS‐4 and MERS‐27 are monoclonal antibodies targeting the RBD of MERS‐CoV S that were discovered in a nonimmune yeast‐display scFv library screening. |
| T166 | 16237-16368 | Sentence | denotes | The more active MERS‐4 potently blocked the infection of DPP4‐expressing Huh‐7 cells with pseudotyped MERS‐CoV (IC50, 0.056 μg/mL). |
| T167 | 16369-16476 | Sentence | denotes | It also prevented MERS‐CoV‐induced cytopathogenic effects in MERS‐infected Vero E6 cells (IC50, 0.5 μg/mL). |
| T168 | 16477-16479 | Sentence | denotes | 42 |
| T169 | 16480-16556 | Sentence | denotes | A heptad repeat (HR) is a repeating structural pattern of seven amino acids. |
| T170 | 16557-16687 | Sentence | denotes | A crucial membrane fusion framework of SARS‐CoV is the 6‐helix‐bundle (6‐HB) that is formed by HR1 and HR2 of the viral S protein. |
| T171 | 16688-16773 | Sentence | denotes | Enfuvirtide (T‐20) is an FDA approved HR2 peptide and the first HIV fusion inhibitor. |
| T172 | 16774-16872 | Sentence | denotes | It has opened up new avenues toward identifying and developing peptides as viral entry inhibitors. |
| T173 | 16873-17143 | Sentence | denotes | Such molecules represent a promising strategy against enveloped viruses with class 1 fusion proteins such as Nipah virus, Hendra virus, Ebola virus, and other paramyxoviruses, simian immunodeficiency virus, feline immunodeficiency virus, and respiratory syncytial virus. |
| T174 | 17144-17343 | Sentence | denotes | 43 , 44 , 45 , 46 The HR regions of SARS‐CoV‐1 and SARS‐CoV‐2 S protein share a high degree of conservation, and such fusion inhibitors have potential applications in preventing SARS‐CoV‐2 entry. |
| T175 | 17344-17427 | Sentence | denotes | Small molecule entry inhibitors, on the other hand, are reported to target the RBD. |
| T176 | 17428-17604 | Sentence | denotes | Compared to peptides, proteins, and biologics, small molecules have several advantages due to lower production costs, improved pharmacokinetics, stability, and dosage accuracy. |
| T177 | 17605-17792 | Sentence | denotes | Sarafianos et al. identified the oxazole‐carboxamide derivative SSAA09E2 (1; Figure 4) as an entry inhibitor against SARS‐CoV‐1 by screening a chemical library composed of 3000 compounds. |
| T178 | 17793-18010 | Sentence | denotes | 47 This inhibitor directly blocks ACE2 recognition by interfering with the RBD with an EC50 value of 3.1 µM and a 50% cytotoxic concentration (CC50) value of greater than 100 µM, not affecting ACE2 expression levels. |
| T179 | 18011-18013 | Sentence | denotes | 48 |
| T180 | 18014-18082 | Sentence | denotes | Figure 4 Inhibitors targeting the receptor‐binding domain Xu et al. |
| T181 | 18083-18262 | Sentence | denotes | 49 identified two small molecules, TGG (2; Figure 4) and luteolin (3; Figure 4), that can bind avidly to the SARS‐CoV‐1 S2 protein and inhibit its entry into Vero E6 cells (EC50: |
| T182 | 18263-18294 | Sentence | denotes | 4.5 µM, 10.6 µM; respectively). |
| T183 | 18295-18446 | Sentence | denotes | Compounds 2 and 3 showed cytotoxicity (CC50) of 1.08 and 0.155 mM, and the selectivity index (SI) values of 2 and 3 were 240.0 and 14.62, respectively. |
| T184 | 18447-18572 | Sentence | denotes | Further studies regarding acute toxicity revealed that the 50% lethal doses of 2 and 3 were ~456 and 232 mg/kg, respectively. |
| T185 | 18573-18679 | Sentence | denotes | These results indicate that these small molecules could be used at relatively high concentrations in mice. |
| T186 | 18680-18834 | Sentence | denotes | 49 Quercetin (4; Figure 4), an analog of 3, also showed antiviral activity against SARS‐CoV‐1, with an EC50 value of 83.4 µM and a CC50 value of 3.32 mM. |
| T187 | 18835-18837 | Sentence | denotes | 50 |
| T188 | 18838-18952 | Sentence | denotes | Ngai et al. reported ADS‐J1 (5; Figure 4) as a potential SARS‐CoV‐1 viral entry inhibitor with an EC50 of 3.89 µM. |
| T189 | 18953-19092 | Sentence | denotes | Molecular docking studies predicted that 5 can bind into a deep pocket of the SARS‐CoV‐1 S HR region and block viral entry into host cells. |
| T190 | 19093-19294 | Sentence | denotes | 51 Imatinib (6; Figure 4), an Abelson kinase inhibitor, could inhibit CoV S protein‐induced fusion with an EC50 value of 10 µM and showed no cytotoxic effects in Vero cells up to 100 µM concentration. |
| T191 | 19295-19303 | Sentence | denotes | 52 , 53 |
| T192 | 19305-19352 | Sentence | denotes | 2.2 Inhibitors targeting the cellular receptor |
| T193 | 19353-19471 | Sentence | denotes | The genetic code of SARS‐CoV‐2 shares noticeable similarities with SARS‐CoV‐1, which caused the SARS epidemic in 2002. |
| T194 | 19472-19552 | Sentence | denotes | 26 , 54 More importantly, both viruses have identical mechanisms of infection. |
| T195 | 19553-19735 | Sentence | denotes | SARS‐CoV‐1 uses the host's ACE2 as a portal to infect cells, which has high expression in the vascular endothelium 55 and the lung, particularly in type 2 alveolar epithelial cells. |
| T196 | 19736-19803 | Sentence | denotes | 56 SARS‐CoV‐2 shares 76% of its spike (S) protein with SARS‐CoV‐1. |
| T197 | 19804-20038 | Sentence | denotes | Despite a few amino acid differences in its RBD compared to the SARS‐CoV‐1 S protein, the SARS‐CoV‐2 S protein binds to ACE2 with even greater affinity 27 offering an explanation for its greater virulence and preference for the lung. |
| T198 | 20039-20207 | Sentence | denotes | ACE, a highly glycosylated type I integral membrane protein, is an essential component of the renin‐angiotensin (Ang) system, which controls blood pressure homeostasis. |
| T199 | 20208-20247 | Sentence | denotes | Both ACE1 and ACE2 cleave Ang peptides. |
| T200 | 20248-20395 | Sentence | denotes | However, they differ markedly: ACE1 cuts and converts the inactive decapeptide Ang I into the octapeptide Ang II by removing the dipeptide His‐Leu. |
| T201 | 20396-20649 | Sentence | denotes | This Ang II induces vaso‐ and bronchoconstriction, increased vascular permeability, inflammation, and fibrosis, thus promoting acute respiratory distress syndrome (ARDS) and lung failure in patients infected with SARS‐CoV‐1 or SARS‐CoV‐2 57 (Figure 5). |
| T202 | 20650-20781 | Sentence | denotes | Therefore, ACE‐inhibitors (ACEis) and angiotensin II receptor blockers (ARBs) could block the disease‐propagating effect of Ang II. |
| T203 | 20782-20796 | Sentence | denotes | 58 , 59 , 60 |
| T204 | 20797-20863 | Sentence | denotes | Figure 5 The roles of ACE1 and 2 in the renin‐angiotensin system. |
| T205 | 20864-20995 | Sentence | denotes | A, Chemical structures of angiotensin‐related peptides and B, Schematic diagram of roles of ACE1 and 2 in renin‐angiotensin system. |
| T206 | 20996-21206 | Sentence | denotes | ACE, angiotensin‐converting enzyme [Color figure can be viewed at wileyonlinelibrary.com] ACE2, on the other hand, is a zinc‐containing metalloenzyme, and shares merely 42% of its amino acid sequence with ACE1. |
| T207 | 21207-21362 | Sentence | denotes | 61 It cleaves only one amino acid residue (Leu or Phe) from Ang I and Ang II, respectively, generating Ang (1–9) and Ang (1–7) (a vasodilator) (Figure 5). |
| T208 | 21363-21453 | Sentence | denotes | Thus, ACE2 has been considered a potential therapeutic target for cardiovascular diseases. |
| T209 | 21454-21720 | Sentence | denotes | Virtual screening combined with a molecular docking approach targeting the ACE2 catalytic site with around 140 000 compounds led to the identification of inhibitor N‐(2‐aminoethyl)‐1 aziridine‐ethanamine (7; Figure 6) with an IC50 value of 57 µM and a K i of 459 µM. |
| T210 | 21721-21805 | Sentence | denotes | However, no information about the cytotoxicity of this compound is available so far. |
| T211 | 21806-21808 | Sentence | denotes | 62 |
| T212 | 21809-21866 | Sentence | denotes | Figure 6 Inhibitors for SARS‐CoV‐1 and 2 targeting ACE2. |
| T213 | 21867-22082 | Sentence | denotes | ACE, angiotensin‐converting enzyme; SARS‐CoV, severe acute respiratory syndrome coronavirus Chloroquine (8; Figure 6) is a relatively safe, cheap, and effective medication for the treatment of malaria and amebiasis. |
| T214 | 22083-22098 | Sentence | denotes | Savarino et al. |
| T215 | 22099-22134 | Sentence | denotes | 63 reported its antiviral effects. |
| T216 | 22135-22275 | Sentence | denotes | At a molecular level, it increases late endosomal and lysosomal pH, resulting in impaired liberation of virions from endosomes or lysosomes. |
| T217 | 22276-22366 | Sentence | denotes | The virus is therefore unable to release its genetic material into the cell and replicate. |
| T218 | 22367-22557 | Sentence | denotes | 64 , 65 Furthermore, they hypothesize that chloroquine might block the production of proinflammatory cytokines (such as IL‐6), thereby blocking the pathway that subsequently leads to ARDS. |
| T219 | 22558-22560 | Sentence | denotes | 63 |
| T220 | 22561-22648 | Sentence | denotes | Chloroquine is reasonably active in vitro against SARS‐CoV‐1, MERS‐CoV, and SARS‐CoV‐2. |
| T221 | 22649-22723 | Sentence | denotes | It was found to inhibit SARS‐CoV‐2 with an EC50 value of 5.47 µM in vitro. |
| T222 | 22724-22913 | Sentence | denotes | 66 Antiviral activity against SARS‐CoV‐1 was reported with an IC50 of 8.8 μM in Vero cells, but it is unclear how this translates into activity in respiratory epithelial cells and in vivo. |
| T223 | 22914-23172 | Sentence | denotes | 67 , 68 Mechanistic studies of chloroquine for SARS‐CoV‐1 infection revealed that it could also weaken the interaction between the RBD of SARS‐CoV‐1 and ACE2 by interfering with terminal glycosylation of ACE2, thereby reducing its affinity to SARS‐CoV‐1 S. |
| T224 | 23173-23175 | Sentence | denotes | 69 |
| T225 | 23176-23422 | Sentence | denotes | During the SARS‐CoV‐2 pandemic, chloroquine has been recommended by Chinese, South Korean, and Italian health authorities for the experimental treatment of COVID‐19, 70 , 71 despite contraindications for patients with heart disease or diabetes. |
| T226 | 23423-23639 | Sentence | denotes | 72 However, health experts and agencies like the US FDA and European Medicines Agency warned against broad uncontrolled use after reports of misuse of low‐quality versions of chloroquine phosphate intended for fish. |
| T227 | 23640-23732 | Sentence | denotes | Hydroxychloroquine (9; Figure 6) is being studied as an experimental treatment for COVID‐19. |
| T228 | 23733-23799 | Sentence | denotes | 73 However, the benefits of treatment with this drug are unclear. |
| T229 | 23800-23802 | Sentence | denotes | 74 |
| T230 | 23803-23893 | Sentence | denotes | Hydroxychloroquine was found to inhibit SARS‐CoV‐2 with an EC50 value of 0.74 µM in vitro. |
| T231 | 23894-23976 | Sentence | denotes | 66 Some studies imply synergistic effects of hydroxychloroquine and azithromycin. |
| T232 | 23977-24186 | Sentence | denotes | Azithromycin is active in vitro against Zika and Ebola virus 75 , 76 and can be used to guard against life‐threatening bacterial superinfections when administered to patients suffering from viral infections. |
| T233 | 24187-24343 | Sentence | denotes | 77 A small study that compared hydroxychloroquine monotherapy and combination treatment with azithromycin found a significant advantage of the combination. |
| T234 | 24344-24741 | Sentence | denotes | While evaluating the efficacy of therapeutic intervention with hydroxychloroquine as monotherapy and its impact in combination with azithromycin, the number of patients testing negative in polymerase chain reaction (PCR) tests was substantially different in the two groups with 100% of patients cured (6 days post inclusion) in the combination arm of the study versus 57% in the monotherapy group. |
| T235 | 24742-24837 | Sentence | denotes | At the same time, 12% of patients in the control group receiving only standard care were cured. |
| T236 | 24838-24846 | Sentence | denotes | 78 , 79 |
| T237 | 24847-25039 | Sentence | denotes | The WHO declared on 18 March that chloroquine and its derivative hydroxychloroquine will be among the four medicines studied in the solidarity clinical trial 80 for the treatment of COVID‐19. |
| T238 | 25040-25166 | Sentence | denotes | In April 2020, the US National Institutes of Health (NIH) also commenced a study with the drug for treating COVID‐19 patients. |
| T239 | 25167-25169 | Sentence | denotes | 81 |
| T240 | 25170-25416 | Sentence | denotes | The recent clinical trial involving 96 032 patients with COVID‐19 concluded that it was unable to confirm a benefit of hydroxychloroquine or chloroquine, when used alone or in combination with a macrolide such as azithromycin (or clarithromycin). |
| T241 | 25417-25528 | Sentence | denotes | 82 The study actually reported decreased survival rates for patients treated with each of these drug regimens. |
| T242 | 25529-25627 | Sentence | denotes | Additionally, patients had an increased risk of developing ventricular arrhythmia under treatment. |
| T243 | 25628-25914 | Sentence | denotes | However, still more evidence is needed to adequately assess the drugs' risks or benefits for the treatment or prevention of COVID‐19 (it is important to note that chloroquine and hydroxychloroquine are still considered safe treatment options in certain autoimmune diseases and malaria). |
| T244 | 25915-26048 | Sentence | denotes | Besides, the WHO announced the premature pause of its clinical trials using hydroxychloroquine as a safety precaution on 24 May 2020. |
| T245 | 26049-26178 | Sentence | denotes | On a different note, it was found that ACE2 undergoes proteolytic shedding; releasing an enzymatic ectodomain during viral entry. |
| T246 | 26179-26314 | Sentence | denotes | 83 A disintegrin and metalloproteinase (ADAM), also known as TNF‐α converting enzyme (TACE), assisted the shedding regulation of ACE2. |
| T247 | 26315-26373 | Sentence | denotes | Inhibition of this enzyme led to reduced shedding of ACE2. |
| T248 | 26374-26477 | Sentence | denotes | GW280264X (10; Figure 6) was found to be a specific inhibitor of ADAM‐induced shedding of ACE2 at 1 nM. |
| T249 | 26478-26614 | Sentence | denotes | 84 Two TACE inhibitors, TAPI‐0 (11) and TAPI‐2 (12; Figure 6), reduced ACE2 shedding, with IC50 values of 100 and 200 nM, respectively. |
| T250 | 26615-26617 | Sentence | denotes | 83 |
| T251 | 26618-26713 | Sentence | denotes | MLN‐4760 (13; Figure 6) inhibited the catalytic activity of ACE2 with an IC50 of around 440 pM. |
| T252 | 26714-26897 | Sentence | denotes | 85 This is the most potent and selective small‐molecule inhibitor against soluble human ACE2 described to date, thus making it a very promising candidate for SARS‐CoV‐2 interference. |
| T253 | 26898-26973 | Sentence | denotes | It binds to the active site zinc and emulates the transition state peptide. |
| T254 | 26974-27045 | Sentence | denotes | However, no antiviral data for this compound is available at this time. |
| T255 | 27046-27205 | Sentence | denotes | The interference of a virus‐host cell fusion, which is mediated by the viral S protein to its receptor ACE2 on host cells, may be a viable prevention strategy. |
| T256 | 27206-27357 | Sentence | denotes | Umifenovir (14; brand name Arbidol), a broad spectrum antiviral drug used against influenza, prevents viral entry by inhibiting virus‐host cell fusion. |
| T257 | 27358-27449 | Sentence | denotes | 86 It is currently being investigated in a clinical trial for the treatment of SARS‐CoV‐2. |
| T258 | 27450-27458 | Sentence | denotes | 87 , 88 |
| T259 | 27459-27555 | Sentence | denotes | Do ACEis or ARBs amplify SARS‐CoV‐2 pathogenicity and aggravate the clinical course of COVID‐19? |
| T260 | 27556-27725 | Sentence | denotes | After ACE2 was recognized as the SARS‐CoV‐2 receptor, 14 , 29 speculations emerged about potentially negative consequences of ACEi or ARB therapy in COVID‐19 patients. |
| T261 | 27726-27813 | Sentence | denotes | This theory caused confusion in the public and alarmed patients taking these medicines. |
| T262 | 27814-27935 | Sentence | denotes | One report said that the expression of ACE2 was increased in patients with heart disease compared to healthy individuals. |
| T263 | 27936-28097 | Sentence | denotes | It was also insisted that ACE2 expression could be increased by taking ACEis and ARBs, 89 although there is no supporting report of this happening in the lungs. |
| T264 | 28098-28307 | Sentence | denotes | In another report, it was suggested that patients suffering from high blood pressure receiving “ACE2‐increasing drugs” have a higher risk for severe COVID‐19, since ACEis and ARBs could elevate levels of ACE2. |
| T265 | 28308-28310 | Sentence | denotes | 90 |
| T266 | 28311-28539 | Sentence | denotes | A joint declaration by the presidents of the HFSA/ACC/AHA on 17 March 2020, 91 followed by a similar statement of the European Medicines Agency, 92 clarified that there was no scientific basis for stopping ACEi or ARB therapy. |
| T267 | 28540-28635 | Sentence | denotes | 93 , 94 , 95 This was in accordance with the editors of the New England Journal of Medicine. |
| T268 | 28636-28638 | Sentence | denotes | 96 |
| T269 | 28639-28809 | Sentence | denotes | In case of SARS‐CoV, the experimental data showed that such medications may be beneficial rather than damaging, which led to a new therapeutic approach for lung diseases. |
| T270 | 28810-28812 | Sentence | denotes | 97 |
| T271 | 28814-28852 | Sentence | denotes | 2.3 Proteolytic processing inhibitors |
| T272 | 28853-29009 | Sentence | denotes | CoVs enter the host cells via both clathrin (endosomal) and nonclathrin pathways (nonendosomal); however, both pathways are dependent upon receptor binding. |
| T273 | 29010-29018 | Sentence | denotes | 98 , 99 |
| T274 | 29019-29184 | Sentence | denotes | The clathrin‐mediated pathway involves the binding of CoV S protein to the host receptor followed by the internalization of vesicles that maturate to late endosomes. |
| T275 | 29185-29392 | Sentence | denotes | Acidification of the endosome promotes the H+‐dependent activation of cellular cathepsin L proteinase in late endosomes and lysosomes, which cleaves and activates the S protein, thus initiating viral fusion. |
| T276 | 29393-29524 | Sentence | denotes | Recent research shows that in addition to ACE2 SARS‐CoV‐2 can also use the host cell receptor CD147 to gain access into host cells. |
| T277 | 29525-29528 | Sentence | denotes | 100 |
| T278 | 29529-29819 | Sentence | denotes | Membrane fusion is also the crucial step for the CoV life cycle in the nonclathrin/endosomal route, in which host proteases such as cathepsin L, TMPRSS2, and TMPRSS11D (airway trypsin‐like protease) cut the S protein at the S1/S2 cleavage site to activate the S protein for membrane fusion. |
| T279 | 29820-29950 | Sentence | denotes | 101 Interference with this process by targeting these proteases could become an attractive strategy for combating CoV infections. |
| T280 | 29951-30056 | Sentence | denotes | A recent study confirms the role of TMPRSS2 for the viral life cycle in SARS‐CoV‐2‐infected VeroE6 cells. |
| T281 | 30057-30168 | Sentence | denotes | 5 Furin (a serine endoprotease) activates MERS‐CoV to initiate the nonclathrin mediated membrane fusion event. |
| T282 | 30169-30172 | Sentence | denotes | 102 |
| T283 | 30173-30385 | Sentence | denotes | The neurotransmitter receptor blockers chlorpromazine (15), promethazine (16), and fluphenazine (17; Figure 7), were reported to inhibit MERS‐CoV and SARS‐CoV‐1 most probably by impeding S protein‐induced fusion. |
| T284 | 30386-30589 | Sentence | denotes | 103 Chlorpromazine, a clathrin‐mediated viral entry inhibitor, was already described to inhibit human CoV‐229E, hepatitis C virus, infectious bronchitis virus, as well as mouse hepatitis virus‐2 (MHV2). |
| T285 | 30590-30621 | Sentence | denotes | 104 , 105 , 106 , 107 , 108 |
| T286 | 30622-30870 | Sentence | denotes | Figure 7 Neurotransmitter inhibitors targeting clathrin/nonclathrin pathways Matsuyama et al. identified the commercially available serine protease inhibitor camostat (18; Figure 8) to be a SARS‐CoV‐1 inhibitor, blocking TMPRSS2 activity at 10 µM. |
| T287 | 30871-31115 | Sentence | denotes | However, at a higher concentration (100 µM), inhibition of viral entry via SARS‐CoV‐1 S protein‐mediated cell fusion never exceeded 65% (inhibition efficiency), indicating that 35% of entry events take place via the endosomal cathepsin pathway. |
| T288 | 31116-31278 | Sentence | denotes | Interestingly, treatment with a combination of EST (a cathepsin inhibitor) and 18 resulted in remarkably blocked infection (>95%) activity of pseudotyped viruses. |
| T289 | 31279-31282 | Sentence | denotes | 109 |
| T290 | 31283-31322 | Sentence | denotes | Figure 8 Inhibitors targeting TMPRSS2. |
| T291 | 31323-31439 | Sentence | denotes | TMPRSS, transmembrane serine protease A similar approach has been investigated to prevent viral entry of SARS‐CoV‐2. |
| T292 | 31440-31574 | Sentence | denotes | Pöhlmann et al. reported the attainment of full inhibition efficiency with a combination of both 18 and E‐64d (a cathepsin inhibitor). |
| T293 | 31575-31718 | Sentence | denotes | Both studies indicate that SARS‐CoV‐1 and 2 enter cells in a similar manner showing the potential of 18 as a candidate for further development. |
| T294 | 31719-31721 | Sentence | denotes | 15 |
| T295 | 31722-31888 | Sentence | denotes | Recently, K11777 (19; Figure 8), a cysteine protease inhibitor, was shown in tissue cultures to inhibit SARS‐CoV‐1 and MERS‐CoV replication in the subnanomolar range. |
| T296 | 31889-32044 | Sentence | denotes | 110 , 111 Future tissue culture and animal model studies should be conducted to clarify, whether its antiviral activity is mediated by targeting TMPRSS2. |
| T297 | 32045-32216 | Sentence | denotes | Teicoplanin is a glycopeptide antibiotic used to prevent infections with Gram‐positive bacteria like methicillin‐resistant Staphylococcus aureus and Enterococcus faecalis. |
| T298 | 32217-32345 | Sentence | denotes | It was found that teicoplanin inhibits the entry of SARS‐CoV‐1, MERS‐CoV, and Ebola virus by specifically targeting cathepsin L. |
| T299 | 32346-32466 | Sentence | denotes | 112 This knowledge has also been used to block the entry of new SARS‐CoV‐2 pseudoviruses with an IC50 value of 1.66 µM. |
| T300 | 32467-32562 | Sentence | denotes | Therefore, teicoplanin could be considered a potential candidate for the treatment of COVID‐19. |
| T301 | 32563-32566 | Sentence | denotes | 113 |
| T302 | 32568-32614 | Sentence | denotes | 2.4 Small‐molecules as cathepsin L inhibitors |
| T303 | 32615-32790 | Sentence | denotes | Human cathepsin L is a cysteine endopeptidase and plays a key role for infection efficiency by activation of the S protein into a fusogenic state to escape the late endosomes. |
| T304 | 32791-32942 | Sentence | denotes | Targeting this protease with small molecules could interfere with virus‐cell entry and therefore be a possible intervention strategy for CoV infection. |
| T305 | 32943-33157 | Sentence | denotes | 114 Bates et al. identified MDL28170 (20; Figure 9) as an antiviral compound that specifically inhibited cathepsin‐L‐mediated substrate cleavage, with an IC50 value of 2.5 nM and EC50 value in the range of 100 nM. |
| T306 | 33158-33258 | Sentence | denotes | However, despite its potent inhibitory activity, no cytotoxicity data for 20 is currently available. |
| T307 | 33259-33262 | Sentence | denotes | 115 |
| T308 | 33263-33466 | Sentence | denotes | Figure 9 Cathepsin L inhibitors with antiviral activity Diamond et al. reported CID 16725315 (21) and CID 23631927 (22; Figure 9) as viral entry inhibitors of SARS‐CoV in a cathepsin L inhibition assay. |
| T309 | 33467-33587 | Sentence | denotes | Compound 21 could block cathepsin L with an IC50 value of 6.9 nM, while 22 showed slightly weaker potency (IC50, 56 nM). |
| T310 | 33588-33700 | Sentence | denotes | Compound 22 was also found to inhibit Ebola virus infection (EC50, 193 nM) of human embryonic kidney 293T cells. |
| T311 | 33701-33796 | Sentence | denotes | This compound did not show any sign of toxicity to human aortic endothelial cells up to 100 µM. |
| T312 | 33797-33889 | Sentence | denotes | This data offers a new promising point for the treatment of SARS and Ebola virus infections. |
| T313 | 33890-33893 | Sentence | denotes | 116 |
| T314 | 33894-34075 | Sentence | denotes | Screening of ~14 000 compounds in a cell‐based assay resulted in the identification of SSAA09E1 (23; Figure 9) as inhibitor of cathepsin L proteinase, with an IC50 value of 5.33 µM. |
| T315 | 34076-34205 | Sentence | denotes | In a pseudotype‐based assay in 293T cells, the EC50 value of 23 was around 6.4 µM, and no cytotoxicity was detected below 100 µM. |
| T316 | 34206-34208 | Sentence | denotes | 48 |
| T317 | 34209-34301 | Sentence | denotes | Phenotypic screening approaches led to the identification of several viral entry inhibitors. |
| T318 | 34302-34429 | Sentence | denotes | This approach has the advantage of finding cellular‐active compounds, providing information on drug solubility and cell uptake. |
| T319 | 34430-34534 | Sentence | denotes | 117 On the other hand, it is limited in terms of capacity compared to in silico target‐based screening. |
| T320 | 34535-34826 | Sentence | denotes | Hsiang et al. identified emodin (24; Figure 9), the active component from Polygonum multiflorum and Rheum officinale, could block the interaction of S protein with ACE2, with an IC50 value of 10 µM and an EC50 value of 200 µM in an S protein‐pseudotyped retrovirus assay using Vero E6 cells. |
| T321 | 34827-34906 | Sentence | denotes | However, the mechanism of action of this compound still needs to be determined. |
| T322 | 34907-34929 | Sentence | denotes | 118 Sarafianos et al. |
| T323 | 34930-35181 | Sentence | denotes | 48 found that SSAA09E3 (25), a benzamide derivative of 24, could prevent virus‐cell membrane fusion in pseudotype‐based and antiviral‐based assays, with an EC50 value of 9.7 µM, but a CC50 value of 20 µM indicates additional unknown cellular targets. |
| T324 | 35182-35344 | Sentence | denotes | VE607 (26) was identified among 50 240 structurally diverse small molecules to specifically inhibit SARS‐CoV‐1 entry into cells using a phenotype‐based screening. |
| T325 | 35345-35451 | Sentence | denotes | Its EC50 value was reported at 3.0 µM and it inhibited SARS‐CoV‐1 plaque formation with an EC50 of 1.6 µM. |
| T326 | 35452-35539 | Sentence | denotes | 119 Cathepsin inhibitor E‐64‐D (27) blocked MERS‐CoV and SARS‐CoV‐1 infection as well. |
| T327 | 35540-35550 | Sentence | denotes | 120 , 121 |
| T328 | 35552-35582 | Sentence | denotes | 3 PROTEASES AS A DRUG TARGETS |
| T329 | 35583-35718 | Sentence | denotes | Papain‐like protease (PLpro), and, predominantly, Mpro are required for the proteolytic cleavage of polyproteins produced by the virus. |
| T330 | 35719-35805 | Sentence | denotes | Together they produce 16 nsp that are involved in viral replication and transcription. |
| T331 | 35806-35994 | Sentence | denotes | 122 PLpro is responsible for cleavage at the first three positions of its polyprotein to produce three nsp, while Mpro cleaves at no less than 11 conserved sites, releasing nsp4 to nsp16. |
| T332 | 35995-36130 | Sentence | denotes | Mpro‐mediated cleavage generates functional proteins like RdRP, RNA binding proteins, exoribonuclease, helicase, and methyltransferase. |
| T333 | 36131-36270 | Sentence | denotes | 123 The indispensable role of Mpro for the viral life cycle and infection process makes Mpro an ideal target for anti‐coronaviral therapy. |
| T334 | 36272-36292 | Sentence | denotes | 3.1 Mpro inhibitors |
| T335 | 36294-36335 | Sentence | denotes | 3.1.1 Structure and function of CoV Mpro |
| T336 | 36336-36376 | Sentence | denotes | Mpro is a homodimeric cysteine protease. |
| T337 | 36377-36423 | Sentence | denotes | The SARS‐CoV‐1 Mpro consists of three domains: |
| T338 | 36424-36602 | Sentence | denotes | I (residues 8–101), and II (residues 102–184), which are β‐barrel domains that shape the chymotrypsin‐like structure, while domain III (residues 201–306) is made up by α‐helices. |
| T339 | 36603-36777 | Sentence | denotes | 124 The CoV Mpro active site uses a catalytic dyad (Cys145‐His41), in which cysteine acts as the nucleophile in the proteolysis while histidine behaves as general acid‐base. |
| T340 | 36778-36855 | Sentence | denotes | The peptide substrate or inhibitor binds in a cleft between domains I and II. |
| T341 | 36856-36859 | Sentence | denotes | 125 |
| T342 | 36860-37008 | Sentence | denotes | As far as the development of new therapeutics against SARS‐ and MERS‐CoV infection is concerned, efforts have mainly focused on protease inhibitors. |
| T343 | 37009-37101 | Sentence | denotes | These enzymes are highly attractive drug targets because they are so essential to the virus. |
| T344 | 37102-37241 | Sentence | denotes | Peptides, peptidomimetics, and even small molecules can inhibit them, which leads to markedly reduced viral transmission and pathogenicity. |
| T345 | 37242-37433 | Sentence | denotes | Although most of the reported molecules display only weak anti‐CoV activity, several of studies elucidated structure–activity relationships that can be used to further improve their activity. |
| T346 | 37434-37458 | Sentence | denotes | 100 , 126 , 127 , 128 |
| T347 | 37460-37500 | Sentence | denotes | 3.1.2 Substrate‐derived Mpro inhibitors |
| T348 | 37501-37591 | Sentence | denotes | To date, no approved drugs or vaccines are available for treating a coronavirus infection. |
| T349 | 37592-37777 | Sentence | denotes | In a race to identify chemotherapeutic options, various approaches, such as chemical synthesis, testing of natural products, and virtual screening of compound libraries, have been used. |
| T350 | 37778-37874 | Sentence | denotes | The systematic design of inhibitors of CoV Mpro was essentially based on the enzyme's substrate. |
| T351 | 37875-38068 | Sentence | denotes | In general, a substrate can be transformed into a good inhibitor by modifying part of its sequence such that it binds to the catalytic cysteine in either a reversible or an irreversible manner. |
| T352 | 38069-38206 | Sentence | denotes | Peptide inhibitors are designed by attaching a reactive group (also known as warhead group) to peptides that mimic the natural substrate. |
| T353 | 38207-38352 | Sentence | denotes | The partial peptide substrate sequence for SARS‐CoV‐1 Mpro is mentioned in Figure 10, indicating the specific subsite of each amino acid residue. |
| T354 | 38353-38410 | Sentence | denotes | Figure 10 A, SARS‐CoV‐1 Mpro partial substrate sequence. |
| T355 | 38411-38463 | Sentence | denotes | B, (Overlay) structures of SARS‐CoV Mpro inhibitors. |
| T356 | 38464-38595 | Sentence | denotes | Mpro, main protease; SARS‐CoV, severe acute respiratory syndrome coronavirus [Color figure can be viewed at wileyonlinelibrary.com] |
| T357 | 38597-38655 | Sentence | denotes | 3.1.3 Inhibitors with Michael acceptor as a warhead group |
| T358 | 38656-38913 | Sentence | denotes | The disclosure of the first crystal structure of the SARS‐CoV‐1 Mpro in complex with a peptidic inhibitor Cbz‐Val‐Asn‐Ser‐Thr‐Leu‐Gln‐chloromethyl ketone (also known as hexapeptide chloromethyl ketone; 28) 125 provided clues for the substrate‐based design. |
| T359 | 38914-39189 | Sentence | denotes | Although it is a substrate analog for the porcine transmissible gastroenteritis CoV (TGEV) Mpro, it offers a structural explanation for the P1‐Gln entering into the specific subsite S1 pocket and decreased P2‐leucine specificity in the hydrophobic S2 site of SARS‐CoV‐1 Mpro. |
| T360 | 39190-39360 | Sentence | denotes | Additionally, rupintrivir (29; AG7088), a peptidomimetic inhibitor of human rhinovirus 3C protease is oriented similar to inhibitor 28 in the binding pocket of TGEV Mpro. |
| T361 | 39361-39463 | Sentence | denotes | 129 These two molecules became prototype compounds for the development of SARS‐CoV‐1 Mpro inhibitors. |
| T362 | 39464-39572 | Sentence | denotes | Compound 29 was only weakly active against SARS‐CoV‐1 Mpro (IC50, 800 µM) also in cellular antiviral assays. |
| T363 | 39573-39686 | Sentence | denotes | 130 However, systematic structural modifications led to a series of analogs that show moderate to good activity. |
| T364 | 39687-39809 | Sentence | denotes | 131 For example, compound 30 (Figure 11), in which the P1‐lactam was replaced by a phenyl ring, showed moderate activity. |
| T365 | 39810-39919 | Sentence | denotes | Compound 31, in which the larger P2 p‐fluorophenyl was replaced with a phenyl group, was even more effective. |
| T366 | 39920-40052 | Sentence | denotes | By taking 29 as a lead, Ghosh et al. designed new molecules mainly focusing on the replacement of the large P2 p‐fluorobenzyl group. |
| T367 | 40053-40273 | Sentence | denotes | Two of the resulting structures with P2‐benzyl (32) and prenyl (33) moieties showed decent inhibitory potencies at both enzymatic (K inact, 0.014 and 0.045 min−1, respectively) and cell‐based (IC50, 45 and 70 µM) assays. |
| T368 | 40274-40364 | Sentence | denotes | 132 Besides, no cytotoxicity was observed for these compounds up to 100 µM concentration. |
| T369 | 40365-40415 | Sentence | denotes | However, 32 and 33 were inactive at MERS‐CoV Mpro. |
| T370 | 40416-40608 | Sentence | denotes | 133 The same research group further modified the molecule with the introduction of P4 Boc‐serine, to establish additional hydrogen bond interactions as described in compound 34 (IC50, 75 µM). |
| T371 | 40609-40680 | Sentence | denotes | Unfortunately, the activity of the resulting compound was not improved. |
| T372 | 40681-40829 | Sentence | denotes | Further modification of the isobutyl group in compound 34 to isoprenyl group in compound 35 displayed potent activity with K i = 3.6 µM (Figure 11). |
| T373 | 40830-40832 | Sentence | denotes | 14 |
| T374 | 40833-40916 | Sentence | denotes | Figure 11 SARS‐CoV Mpro inhibitors containing Michael acceptor as a warhead group. |
| T375 | 40917-41024 | Sentence | denotes | Mpro, main protease; SARS‐CoV, severe acute respiratory syndrome coronavirus On the other hand, Yang et al. |
| T376 | 41025-41104 | Sentence | denotes | 134 reported a series of peptide inhibitors with a greater inhibitory potency. |
| T377 | 41105-41174 | Sentence | denotes | In general, they systematically changed the backbone of inhibitor 29. |
| T378 | 41175-41284 | Sentence | denotes | As a result, they were able to identify more specific residues for each subsite (compounds 36–38; Figure 12): |
| T379 | 41285-41606 | Sentence | denotes | At first, the P1‐lactam ring was identified as a more specific moiety for the S1‐site, forming multiple hydrogen‐bond interactions with the enzyme as can be seen in the crystal structure (36); P2‐leucine showed a fourfold increased inhibitory activity when compared to the P2‐phenylalanine or ‐4‐fluorophenylalanine (37). |
| T380 | 41607-41703 | Sentence | denotes | A lipophilic tert‐butyl residue was recognized to be a better P3‐moiety than the P3‐valine (38). |
| T381 | 41704-41838 | Sentence | denotes | Finally, the replacement of P4‐methylisoxazole with a benzyloxy group was the best option for activity enhancement (compare 29 vs 36). |
| T382 | 41839-41930 | Sentence | denotes | They all showed moderate to high antiviral activity against HCoV‐229E in cell‐based assays. |
| T383 | 41931-42018 | Sentence | denotes | Figure 12 Broad‐spectral antiviral compounds containing a Michael acceptor Shie et al. |
| T384 | 42019-42147 | Sentence | denotes | 131 reported another series of peptide inhibitors with comparatively reduced molecular weight to increase drug‐like properties. |
| T385 | 42148-42239 | Sentence | denotes | These pseudo‐C2‐symmetric inhibitors consist of a Phe‐Phe‐dipeptidic α,β‐unsaturated ester. |
| T386 | 42240-42354 | Sentence | denotes | One of these inhibitors (39) had an outstanding inhibitory activity with an EC50 value of 0.52 µM (see Figure 12). |
| T387 | 42355-42437 | Sentence | denotes | Besides, it displayed remarkable antiviral activity with an EC50 value of 0.18 µM. |
| T388 | 42438-42552 | Sentence | denotes | Structurally, the presence of 4‐dimethylamine on the phenyl ring was found to be crucial for activity enhancement. |
| T389 | 42553-42688 | Sentence | denotes | Another peptidic drug with a Michael acceptor was N3 (40), which was reported to inhibit SARS‐CoV‐1 3CLpro (K i, 9.0 µM) by Yang et al. |
| T390 | 42689-42860 | Sentence | denotes | It was observed to be a broad‐spectrum antiviral compound, also inhibiting other CoVs, such as MERS‐CoV Mpro (IC50, 0.28µM), 135 HCoV‐229E, HCoV‐NL63, and HCoV‐HKU1 Mpro. |
| T391 | 42861-42983 | Sentence | denotes | 135 , 136 , 137 , 138 It has also exhibited high antiviral activity in an animal model of infectious bronchitis virus. |
| T392 | 42984-43027 | Sentence | denotes | 137 The CC50 of 40 is greater than 133 μM. |
| T393 | 43028-43098 | Sentence | denotes | SARS‐CoV‐2 shares only 82% of its genome with its relative SARS‐CoV‐1. |
| T394 | 43099-43195 | Sentence | denotes | However, essential viral enzymes of both species show sequence similarities of greater than 90%. |
| T395 | 43196-43315 | Sentence | denotes | 137 , 139 , 140 , 141 , 142 SARS‐CoV‐2 3CLpro is highly similar to SARS‐CoV‐1 3CLpro, sharing 96% of its sequence. |
| T396 | 43316-43411 | Sentence | denotes | Therefore, one could expect that SARS‐CoV‐1 Mpro inhibitors are active against SARS‐CoV‐2 Mpro. |
| T397 | 43412-43567 | Sentence | denotes | Compound 40 was found to be active against SARS‐CoV‐2 Mpro and its value of kobs/[I] for the COVID‐19 virus Mpro was determined to be 11 300 ± 880 M−1·s−1. |
| T398 | 43568-43660 | Sentence | denotes | 143 Peptide N3 was co‐crystalized with SARS‐CoV‐1 Mpro at 2.1 Å resolution (see Figure 13). |
| T399 | 43661-43751 | Sentence | denotes | Its binding mode to SARS‐CoV‐2 Mpro is highly similar to that of other CoV main proteases. |
| T400 | 43752-43880 | Sentence | denotes | Some key features include the Cys‐His catalytic dyad and the substrate‐binding pocket situated in a gap between domain I and II. |
| T401 | 43881-44067 | Sentence | denotes | Figure 13 The crystal structure of COVID‐19 virus Mpro in complex with N3. (A) Representation of the dimeric Mpro‐inhibitor complex. (B) Surface representation of the homodimer of Mpro. |
| T402 | 44068-44221 | Sentence | denotes | Protomer A (blue), protomer B (salmon), compound N3 is presented as green sticks. (C) Schematic view of compound N3 (40) in the substrate‐binding pocket. |
| T403 | 44222-44496 | Sentence | denotes | 143 Mpro, main protease [Color figure can be viewed at wileyonlinelibrary.com] In general, inhibitors possessing a Michael acceptor group as a warhead moiety could form an irreversible (covalent) bond with the catalytic cysteine residue in the following manner (Figure 14): |
| T404 | 44497-44600 | Sentence | denotes | First, the cysteine residue undergoes 1,4‐addition at the inhibitor's Michael acceptor group (warhead). |
| T405 | 44601-44749 | Sentence | denotes | Rapid protonation of the α‐carbanion from His‐H+ leads to the covalent bond formation between the warhead of the inhibitor and the cysteine residue. |
| T406 | 44750-44867 | Sentence | denotes | Figure 14 Mechanism of inhibitors with Michael acceptor group [Color figure can be viewed at wileyonlinelibrary.com] |
| T407 | 44869-44919 | Sentence | denotes | 3.1.4 Inhibitors with aldehyde as a warhead group |
| T408 | 44920-45229 | Sentence | denotes | Although the above‐described inhibitors with 1,4‐Michael acceptors (e.g., α,β‐vinyl ethyl ester, –CH═CH–C(O)–OEt) showed enzymatic or cell‐based in‐vitro activities, they can be cleaved to their carboxylic acids by plasma esterases; for instance, AG7088 (29) was inactive in the plasma of rodents and rabbits. |
| T409 | 45230-45323 | Sentence | denotes | 144 , 145 Therefore, scientists explored different reactive groups that are stable in vivo. |
| T410 | 45324-45456 | Sentence | denotes | Based on the highly potent 1,4‐Michael‐acceptor‐based inhibitor 38, which they had previously developed (see Figure 15), Yang et al. |
| T411 | 45457-45552 | Sentence | denotes | 134 designed a peptide with a new efficient cysteine‐reactive group, using an aldehyde moiety. |
| T412 | 45553-45706 | Sentence | denotes | In addition, the P2‐leucine and the Michael groups of 38 were modified by a cyclohexyl unit and aldehyde group respectively to improve cellular activity. |
| T413 | 45707-45826 | Sentence | denotes | Indeed, the resulting peptide‐aldehyde 41 (Figure 15) showed remarkable activity against SARS‐CoV‐1 and HCoV‐229E Mpro. |
| T414 | 45827-45972 | Sentence | denotes | 134 It displayed promising antiviral activities decreasing viral load by 4.7 log (at 5 µM) for SARS‐CoV‐1 and 5.2 log (at 1.2 µM) for HCoV‐229E. |
| T415 | 45973-46101 | Sentence | denotes | This compound was stable in rat, mouse, and human plasma (even after 120 min, more than 70% of it remained in respective cells). |
| T416 | 46102-46189 | Sentence | denotes | Figure 15 SARS‐CoV‐1 and MERS‐CoV Mpro inhibitors with peptide aldehyde functionality. |
| T417 | 46190-46279 | Sentence | denotes | Mpro, main protease; SARS‐CoV, severe acute respiratory syndrome coronavirus Kumar et al. |
| T418 | 46280-46370 | Sentence | denotes | 146 reported another series of peptide‐aldehyde inhibitors with reduced molecular weight. |
| T419 | 46371-46424 | Sentence | denotes | Selected examples (42, 43) are depicted in Figure 15. |
| T420 | 46425-46554 | Sentence | denotes | They were potent, cell‐membrane permeable, dual Mpro inhibitors of SARS‐CoV‐1 and MERS‐CoV, without cytotoxicity (CC50 > 100 µM). |
| T421 | 46555-46687 | Sentence | denotes | Compound 43, in particular, revealed highly potent activity against SARS‐CoV‐1 Mpro (IC50, 0.2 µM) and MERS‐CoV Mpro (IC50, 1.7 µM). |
| T422 | 46688-46824 | Sentence | denotes | It displayed antiviral activity (EC50, 0.06 µM) lowering the viral load and the secretion of virus particles in MERS‐CoV‐infected cells. |
| T423 | 46825-46912 | Sentence | denotes | Also, it displayed broad‐spectrum antiviral activity against other human α‐ and β‐CoVs. |
| T424 | 46913-47019 | Sentence | denotes | Akaji et al. discovered a series of SARS‐CoV‐1 Mpro inhibitors derived from its natural peptide substrate. |
| T425 | 47020-47135 | Sentence | denotes | Initially, they designed a pentapeptide (Ac‐Ser‐Val‐Leu‐N(CH3)2Gln‐CHO, 44) with Mpro inhibitory activity of 37 µM. |
| T426 | 47136-47241 | Sentence | denotes | 147 SAR studies of 44 led to inhibitor containing P1‐imidazole with improved potency (45; IC50, 5.7 µM). |
| T427 | 47242-47505 | Sentence | denotes | Further systematic structural modifications, primarily concentrating on P1‐, P2‐, and P4‐moieties, driven by X‐ray structure‐based analyses of the Mpro‐inhibitor complex, led to the identification of inhibitor 46 with remarkable inhibitory activity (IC50, 98 nM). |
| T428 | 47506-47605 | Sentence | denotes | The crystal structure of Mpro with 46 revealed significant binding interactions in the active site. |
| T429 | 47606-47771 | Sentence | denotes | The P1‐imidazole nitrogen atom created a hydrogen bond with the histidine residue's imidazole nitrogen, and the P2‐cyclohexyl moiety fitted well into the S2‐subsite. |
| T430 | 47772-47863 | Sentence | denotes | This compound was characterized as a competitive inhibitor without covalent bond formation. |
| T431 | 47864-48057 | Sentence | denotes | The same research group disclosed a novel series of peptide inhibitors containing a decahydroisoquinoline moiety in place of P2‐cyclohexyl of 46 to reduce the peptidic nature of the inhibitors. |
| T432 | 48058-48104 | Sentence | denotes | A few examples (47–51) are shown in Figure 16. |
| T433 | 48105-48189 | Sentence | denotes | Among them, 49 was moderately more active against SARS‐CoV Mpro when compared to 46. |
| T434 | 48190-48386 | Sentence | denotes | 148 The X‐ray structure of Mpro in complex with 49 revealed that the P2‐decahydroisoquinoline moiety was fittingly placed in the S2‐subsite, while the P1‐imidazole moiety occupied the S1‐subsite. |
| T435 | 48387-48526 | Sentence | denotes | With these key residues located appropriately in their respective pockets, the terminal functional group fits tightly into the active site. |
| T436 | 48527-48763 | Sentence | denotes | Figure 16 Peptide inhibitors containing cyclohexyl and decahydroisoquinoline groups [Color figure can be viewed at wileyonlinelibrary.com] This group further extended their study to find inhibitors that interact with S2 to S4 subsites. |
| T437 | 48764-48911 | Sentence | denotes | Taking 49 as a lead, they designed a new compound, by combining a nonprime substituent at the decahydroisoquinoline moiety, as shown in example 52. |
| T438 | 48912-49009 | Sentence | denotes | 149 The resulting 52 showed more than twofold increased Mpro inhibitory activity compared to 49. |
| T439 | 49010-49101 | Sentence | denotes | This indicates that the additional interactions at S2–S4 sites enhance inhibitory activity. |
| T440 | 49102-49258 | Sentence | denotes | Rather recently, the same research group explored the ability of octahydroisochromene to interact with the hydrophobic S2 pocket as an innovative P2‐moiety. |
| T441 | 49259-49351 | Sentence | denotes | 150 To identify the best specific configuration, all possible diastereomers were evaluated. |
| T442 | 49352-49537 | Sentence | denotes | It was found that the molecule with (1S,3S)‐octahydroisochromene 53–56 could secure the optimal position of the P1‐imidazole as well as the aldehyde functional group at the active site. |
| T443 | 49538-49700 | Sentence | denotes | Additionally, the N‐butyl side chain attached to the 1‐position of the fused ring system was recognized to be important for establishing hydrophobic interactions. |
| T444 | 49701-49724 | Sentence | denotes | In 2018, Groutas et al. |
| T445 | 49725-49857 | Sentence | denotes | 151 disclosed a novel class of dual MERS‐CoV and SARS‐CoV‐1 Mpro inhibitors that contain a P3‐piperidine moiety (58–59; Figure 17). |
| T446 | 49858-50084 | Sentence | denotes | These inhibitors were derived from the dipeptidic‐aldehyde bisulfite adduct 57 (GC376), which was clinically studied as a protease inhibitor for its efficacy against CoVs such as the feline infectious peritonitis virus (FIPV). |
| T447 | 50085-50218 | Sentence | denotes | Compounds 58 and 59 showed potent antiviral activity toward MERS‐CoV in cell‐based bioassays (EC50, 0.5 µM for 58 and 0.8 µM for 59). |
| T448 | 50219-50354 | Sentence | denotes | SAR studies revealed that the piperidine moiety engaged in favorable hydrophobic interactions at the S3 and S4 pockets of the protease. |
| T449 | 50355-50597 | Sentence | denotes | Figure 17 Inhibitors with aldehyde, aldehyde bisulfite adduct, and epoxide warhead group The X‐ray crystal structures of MERS‐CoV 3CLpro in complex with inhibitor 59 showed that the piperidine ring is likely projecting toward the S4 subsite. |
| T450 | 50598-50679 | Sentence | denotes | Additionally, 59 was engaged in backbone H‐bonds with Gln192, Gln167, and Glu169. |
| T451 | 50680-50828 | Sentence | denotes | Azapeptide epoxides (APEs) are another class of SARS‐CoV‐1 Mpro inhibitors, although they were originally developed for clan CD cysteine peptidases. |
| T452 | 50829-50980 | Sentence | denotes | 152 , 153 The epoxide S,S‐diastereomer 60 (K inact/K i, 1900 (±400) M−1·s−1; Figure 17) exhibited the best inhibitory activity against SARS‐CoV Mpro. |
| T453 | 50981-51124 | Sentence | denotes | 154 The X‐ray structure of Mpro in complex with 60 confirmed the formation of a covalent bond between the cysteine‐S atom and the epoxide C‐3. |
| T454 | 51125-51205 | Sentence | denotes | It is worth noting that the S,S‐configured epoxide is required for the activity. |
| T455 | 51206-51446 | Sentence | denotes | Very recently, Dai et al. designed and synthesized two novel peptidomimetic SARS‐CoV‐2 Mpro inhibitors 61 and 62 (Figure 18) which exhibited extremely high inhibitory activity on purified Mpro with IC50 values of 50 and 40 nM, respectively. |
| T456 | 51447-51581 | Sentence | denotes | Furthermore, the group observed high antiviral activity of both compounds in cell‐based assays (61: EC50, 0.42 µM; 62: EC50, 0.33 µM). |
| T457 | 51582-51735 | Sentence | denotes | X‐ray structures were determined for both derivatives in complex with SARS‐CoV‐2 Mpro at 1.5 Å, providing detailed information about the binding pockets. |
| T458 | 51736-51892 | Sentence | denotes | Similar to related molecules that employ the aldehyde moiety as a warhead, a covalent bond with the active‐site Cys145 was demonstrated for both structures. |
| T459 | 51893-51954 | Sentence | denotes | Cytotoxicity assays revealed CC50 values greater than 100 µM. |
| T460 | 51955-51958 | Sentence | denotes | 155 |
| T461 | 51959-52034 | Sentence | denotes | Figure 18 Peptidomimetic SARS‐CoV‐2 Mpro inhibitors with P3‐indole moiety. |
| T462 | 52035-52111 | Sentence | denotes | Mpro, main protease; SARS‐CoV, severe acute respiratory syndrome coronavirus |
| T463 | 52113-52140 | Sentence | denotes | 3.1.5 Ketoamide inhibitors |
| T464 | 52141-52311 | Sentence | denotes | Liu et al. reported dipeptidic α‐ketoamides as broad‐spectrum antiviral agents against the main proteases of human α and β‐CoVs as well as the 3C protease of enterovirus. |
| T465 | 52312-52565 | Sentence | denotes | The α‐ketoamide warhead group was promising, as it provides two hydrogen bond acceptors—one from the keto and one from the amide oxygen—whereas other warhead groups, such as Michael acceptor esters and aldehydes, provide only one hydrogen bond acceptor. |
| T466 | 52566-52662 | Sentence | denotes | Compound 63 was identified as SARS‐CoV Mpro inhibitor with an IC50 value of 1.95 µM (Figure 19). |
| T467 | 52663-52666 | Sentence | denotes | 156 |
| T468 | 52667-52725 | Sentence | denotes | Figure 19 Ketoamide inhibitors targeting SARS‐CoV‐2 Mpro. |
| T469 | 52726-52999 | Sentence | denotes | Mpro, main protease; SARS‐CoV, severe acute respiratory syndrome coronavirus Taking 63 as a lead, aided by its X‐ray structure in complex with SARS‐CoV‐1, HCoV‐NL63, and coxsackievirus Mpros, systematic structural modifications were investigated, focusing on the P2‐moiety. |
| T470 | 53000-53189 | Sentence | denotes | As a result, the replacement of P2‐phenyl with P2‐cyclohexyl (64) was found to be the best substitution, while P2‐cyclopentyl (65) showed similar potency against the enzyme SARS‐CoV‐1 Mpro. |
| T471 | 53190-53349 | Sentence | denotes | In Huh7 cells, 64 also showed strong antiviral activity with an EC50 of 400 pM, but in Vero cells the antiviral activity of 64 was drastically reduced to 5 µM. |
| T472 | 53350-53453 | Sentence | denotes | This compound also exhibited antiviral activity against a range of enteroviruses in various cell lines. |
| T473 | 53454-53596 | Sentence | denotes | Due to the high similarity between SARS‐CoV‐1 Mpro and SARS‐CoV‐2 Mpro authors speculated that 64 was likely to inhibit the new virus as well. |
| T474 | 53597-53703 | Sentence | denotes | Zhang et al. recently reported this molecule as a SARS‐CoV‐2 Mpro inhibitor with an IC50 value of 0.18 µM. |
| T475 | 53704-53877 | Sentence | denotes | They first resolved the unliganded crystal structure of SARS‐CoV‐2 Mpro (Figure 20), 157 which is largely identical to that of SARS‐CoV‐1 Mpro with a 96% sequence identity. |
| T476 | 53878-54019 | Sentence | denotes | Compound 64 was docked to SARS‐CoV‐2 Mpro, and a series of structural modifications were performed to improve its pharmacokinetic properties. |
| T477 | 54020-54276 | Sentence | denotes | Specifically, masking the P2‐P3 amide bond with the pyridone ring could improve plasma half‐life; and exchanging the lipophilic cinnamoyl residue for the less lipophilic Boc group, could increase plasma solubility and reduce its binding to plasma proteins. |
| T478 | 54277-54325 | Sentence | denotes | Figure 20 Crystal structure of SARS‐CoV‐2 Mpro. |
| T479 | 54326-54586 | Sentence | denotes | 157 Mpro, main protease; SARS‐CoV, severe acute respiratory syndrome coronavirus [Color figure can be viewed at wileyonlinelibrary.com] Indeed, the resulting 66 had a ~3‐fold improved plasma half‐life in mice when compared to the lead 65 (from 18 min to 1 h). |
| T480 | 54587-54792 | Sentence | denotes | The in vitro kinetic plasma solubility has been increased by a factor of ~19 (from 6 µM for the lead to 112 µM for best derivative), and the thermodynamic solubility by a factor of ~13 (from 41 to 530 µM). |
| T481 | 54793-54857 | Sentence | denotes | Compound 66 also showed reduced binding to mouse plasma protein. |
| T482 | 54858-55035 | Sentence | denotes | However, compared to the lead (IC50, 0.18 µM), the structural modifications caused a reduction of activity against SARS‐CoV‐2 Mpro (IC50, 2.39 µM) and enteroviral 3 C proteases. |
| T483 | 55036-55180 | Sentence | denotes | Nevertheless, the introduction of a cyclopropyl group as in 67 instead of P2‐cyclohexyl enhanced the antiviral activity against β‐coronaviruses. |
| T484 | 55181-55264 | Sentence | denotes | Compound 67 (Figure 19) inhibited purified SARS‐CoV‐2 Mpro with an IC50 of 0.67 µM. |
| T485 | 55265-55370 | Sentence | denotes | It also inhibited SARS‐CoV‐1 Mpro (IC50, 0.90 µM) and MERS‐CoV Mpro (IC50, 0.58 µM) with similar potency. |
| T486 | 55371-55449 | Sentence | denotes | It was effective against SARS‐CoV‐1 replication with an EC50 value of 1.75 µM. |
| T487 | 55450-55685 | Sentence | denotes | In SARS‐CoV‐2 infected human Calu3 cells, it inhibited the viral replication with an EC50 of 4–5 µM, when in fact the Boc‐unprotected 68 was inactive, suggesting a bulky hydrophobic group is necessary for cellular membrane penetration. |
| T488 | 55686-55843 | Sentence | denotes | On the other hand, increasing hydrophobicity of molecules should be pondered carefully, as it can increase plasma protein binding as it was described for 64. |
| T489 | 55844-55990 | Sentence | denotes | The pharmacokinetic properties of 67 revealed striking lung tropism and was suitable for inhalation in mice without any perceived adverse effects. |
| T490 | 55991-56092 | Sentence | denotes | Compound 67 was cocrystallized with the enzyme in two different forms at 1.95 and 2.20 Å (Figure 21). |
| T491 | 56093-56271 | Sentence | denotes | The key feature observed from this crystal structure was that the inhibitor binds to the shallow substrate‐binding site at the surface of each protomer, between domains I and II. |
| T492 | 56272-56567 | Sentence | denotes | The thioketal that resulted from the nucleophilic Cys145 attacking the inhibitor, is stabilized by a H‐bond from His41, whereas the amide oxygen of 67 accepts a H‐bond from the main‐chain amides of Gly143, Cys145, and in part, Ser144 that make up the cysteine protease's canonical oxyanion hole. |
| T493 | 56568-56755 | Sentence | denotes | 157 The P1 lactam moiety is deeply embedded in the S1 pocket where the lactam nitrogen donates a three‐center H‐bond to the main chain oxygen of the Phe140 and the carboxylate of Glu166. |
| T494 | 56756-56801 | Sentence | denotes | The carbonyl oxygen forms a H‐bond to His163. |
| T495 | 56802-56853 | Sentence | denotes | The P2‐cyclopropyl moiety fits into the S2 subsite. |
| T496 | 56854-56945 | Sentence | denotes | The P3‐P2 pyridone moiety occupies the space normally filled by the substrate's main chain. |
| T497 | 56946-57126 | Sentence | denotes | The Boc group is not situated in the canonical S4 site, rather it is located near Pro168, which explains why the removal of the Boc group as in 68 weakened the inhibitory activity. |
| T498 | 57127-57183 | Sentence | denotes | Figure 21 Crystal structure of 67 with SARS‐CoV‐2 Mpro. |
| T499 | 57184-57315 | Sentence | denotes | Mpro, main protease; SARS‐CoV, severe acute respiratory syndrome coronavirus [Color figure can be viewed at wileyonlinelibrary.com] |
| T500 | 57317-57360 | Sentence | denotes | 3.1.6 Inhibitors with electrophilic ketone |
| T501 | 57361-57695 | Sentence | denotes | It was envisioned that a fluorinated ketone moiety could be utilized as a warhead for targeting proteases, because it forms a thermodynamically stable hemiketal or hemithioketal after nucleophilic attack by Ser‐OH or Cys‐SH residues, which are present in the active sites of serine or cysteine proteases, respectively (see Figure 22). |
| T502 | 57696-57984 | Sentence | denotes | Figure 22 Peptide inhibitors containing electrophilic ketone warheads [Color figure can be viewed at wileyonlinelibrary.com] Initially, Hayashi et al. reported a series of natural‐substrate‐derived peptide inhibitors containing a trifluoromethyl ketone warhead targeting SARS‐CoV‐1 Mpro. |
| T503 | 57985-58087 | Sentence | denotes | Compound 69 (Figure 22) was the best of the series with a K i value of 116 µM against SARS‐CoV‐1 Mpro. |
| T504 | 58088-58267 | Sentence | denotes | 158 It was sequentially modified mainly focusing on the warhead moiety since the formation of a cyclic structure prevented the nucleophilic attack by cysteine at the active site. |
| T505 | 58268-58416 | Sentence | denotes | This study led to the discovery of 70 containing a P1‐lactam and P1'‐thiazole moiety with a >50‐fold increase in inhibitory activity compared to 69. |
| T506 | 58417-58549 | Sentence | denotes | 159 Docking studies of 70 to Mpro highlighted key H‐bond interactions with backbone amino acid residues Cys143, Ser144, and Cys145. |
| T507 | 58550-58687 | Sentence | denotes | The nitrogen atom of the thiazole warhead moiety also engaged in H‐bond interactions, and the P1‐lactam nicely fitted into the S1‐pocket. |
| T508 | 58688-58855 | Sentence | denotes | Continued computer‐assisted structural design led to a tripeptide containing benzothiazole as a warhead group and an m‐N,N‐dimethylaminophenyl group as P4‐moiety (71). |
| T509 | 58856-58956 | Sentence | denotes | 160 This compound was extremely potent in inhibiting Mpro of SARS‐CoV‐1 with a K i value of 3.1 nM. |
| T510 | 58957-59055 | Sentence | denotes | Docking studies of 71 confirmed that the benzothiazole group was tightly bound to the active site. |
| T511 | 59056-59203 | Sentence | denotes | Consequently, the same research group disclosed a series of dipeptides with reduced molecular weight in an attempt to improve drug‐like properties. |
| T512 | 59204-59288 | Sentence | denotes | The P3‐valine in the tripeptide 71 was exchanged for a variety of functional groups. |
| T513 | 59289-59356 | Sentence | denotes | 161 The study determined N‐arylglycyl to be the optimal P3‐moiety. |
| T514 | 59357-59408 | Sentence | denotes | Compound 72 displayed the best inhibitory activity. |
| T515 | 59409-59633 | Sentence | denotes | Docking studies of 72 to the protease highlighted the amino hydrogen of the P3‐N‐phenyl glycyl forming a H‐bond with backbone Glu166 of Mpro, in addition to the best P2‐leucine and P1'‐benzthiazole moieties (see Figure 23A). |
| T516 | 59634-59873 | Sentence | denotes | Further structural optimization at the P3‐N‐arylglycyl moiety found the indole‐2 carbonyl group to be one of the best P3‐moeities, thus reaching inhibitors with low nanomolar potency, for example 73 (K i, 0.006 µM) against SARS‐CoV‐1 Mpro. |
| T517 | 59874-60085 | Sentence | denotes | 162 Docking studies of compound 73 to the protease revealed that the indole amino hydrogen and the carbonyl group attached to the 2‐position formed H‐bond interactions with the backbone Glu166 (see Figure 23B). |
| T518 | 60086-60285 | Sentence | denotes | These interactions are of great importance, seeing as shifting the position of the carbonyl group from position 2 to 3, or replacing the indole with benzofuran drastically reduced inhibitory potency. |
| T519 | 60286-60353 | Sentence | denotes | Figure 23 (A) Docking poses of 72 and (B) 73 with SARS‐CoV‐1 Mpro. |
| T520 | 60354-60543 | Sentence | denotes | Mpro, main protease; SARS‐CoV, severe acute respiratory syndrome coronavirus [Color figure can be viewed at wileyonlinelibrary.com] Zhao et al. reported a series of trifluoromethyl ketones. |
| T521 | 60544-60700 | Sentence | denotes | Among them, 74, which has the same sequence as the peptide substrate from sites P1 to P4, exhibited moderate inhibitory activity with an IC50value of 10 µM. |
| T522 | 60701-60769 | Sentence | denotes | Inhibitor 74 also displayed time‐dependent inhibition (K i, 0.3 µM). |
| T523 | 60770-60773 | Sentence | denotes | 163 |
| T524 | 60774-60883 | Sentence | denotes | Zhang et al. described a series of dipeptides containing difluoromethyl ketone as SARS‐CoV‐1 Mpro inhibitors. |
| T525 | 60884-61006 | Sentence | denotes | Compound 75 displayed the best inhibitory activity in infected Vero and Caco‐2 cell cultures with an IC50 value of 2.5 µM. |
| T526 | 61007-61041 | Sentence | denotes | It also exhibited little toxicity. |
| T527 | 61042-61045 | Sentence | denotes | 164 |
| T528 | 61046-61146 | Sentence | denotes | A library of small peptide‐anilides was developed as anti‐SARS‐CoV‐1 Mpro agents (77–80; Figure 23). |
| T529 | 61147-61251 | Sentence | denotes | These inhibitors were basically designed from niclosamide (76) which was inactive at Mpro of SARS‐CoV‐1. |
| T530 | 61252-61327 | Sentence | denotes | Proper structural modifications led to the discovery of 77 (IC50, 0.06 µM). |
| T531 | 61328-61394 | Sentence | denotes | It behaved as a competitive, noncovalent inhibitor (K i, 0.03 µM). |
| T532 | 61395-61542 | Sentence | denotes | SAR investigations pointed out that the N,N‐dimethyl group on the phenyl ring, and electron‐withdrawing groups at the warhead phenyl are important. |
| T533 | 61543-61630 | Sentence | denotes | Structural modification of 77 resulted in compounds 78 – 80 displaying reduced potency. |
| T534 | 61631-61634 | Sentence | denotes | 165 |
| T535 | 61635-61795 | Sentence | denotes | A novel series of ketoglutamide tripeptides bearing a phthalhydrazido warhead group were identified as reversible SARS‐CoV‐1 Mpro inhibitors (81–84; Figure 24). |
| T536 | 61796-61867 | Sentence | denotes | 166 Among them, compound 83 showed the best inhibition (IC50, 0.6 µM). |
| T537 | 61868-62124 | Sentence | denotes | SAR studies revealed the presence of β and β'‐amino functionality adjacent to the keto and the intramolecular hydrogen bond to the carbonyl group made the keto center more electrophilic and inclined to build a hemithioacetal with Cys‐SH at the active site. |
| T538 | 62125-62263 | Sentence | denotes | Additionally, the hydrophobic P3‐benzyloxy moiety, the P1‐lactam, and the nitro group significantly contributed to the activity increment. |
| T539 | 62264-62353 | Sentence | denotes | Figure 24 Small peptide anilides and ketoglutamide tripeptides as SARS‐CoV‐1 inhibitors. |
| T540 | 62354-62421 | Sentence | denotes | SARS‐CoV, severe acute respiratory syndrome coronavirus Wang et al. |
| T541 | 62422-62558 | Sentence | denotes | 167 described the development of selective and reversible SARS‐CoV‐1 Mpro inhibitors derived from HIV proteases inhibitors (Figure 25). |
| T542 | 62559-62657 | Sentence | denotes | The compound 85 as a SARS‐CoV‐1 Mpro lead inhibitor was continuously modified to obtain 86 and 87. |
| T543 | 62658-62741 | Sentence | denotes | These derivatives were highly selective toward SARS‐CoV‐1 Mpro versus HIV protease. |
| T544 | 62742-62877 | Sentence | denotes | Docking studies of 87 to Mpro demonstrated that both indole amino hydrogens establish H‐bond networks with side chain His142 and His41. |
| T545 | 62878-62954 | Sentence | denotes | Figure 25 SARS‐CoV‐1 Mpro inhibitors derived from HIV proteases inhibitors. |
| T546 | 62955-63066 | Sentence | denotes | HIV, human immunodeficiency virus; Mpro, main protease; SARS‐CoV, severe acute respiratory syndrome coronavirus |
| T547 | 63068-63108 | Sentence | denotes | 3.1.7 Small molecule inhibitors of Mpro |
| T548 | 63109-63229 | Sentence | denotes | Benzotriazole esters (88–91; Figure 26) were discovered as novel nonpeptidic irreversible inhibitors of SARS‐CoV‐1 Mpro. |
| T549 | 63230-63347 | Sentence | denotes | 168 Among them, 91 exhibited the best enzymatic inhibitory activity, but no antiviral activity in cell‐based assays. |
| T550 | 63348-63457 | Sentence | denotes | The covalent binding mode of 91 was confirmed by electrospray ionization mass spectrometry (ESI‐MS) analyses. |
| T551 | 63458-63513 | Sentence | denotes | Figure 26 Active esters as SARS‐CoV‐1 Mpro inhibitors. |
| T552 | 63514-63783 | Sentence | denotes | Mpro, main protease; SARS‐CoV, severe acute respiratory syndrome coronavirus With a slight structural modification from benzotriazole ester, Zhang et al. reported a series of active halopyridyl esters containing thiophene, furan, and indole moieties (92–95; Figure 26). |
| T553 | 63784-63870 | Sentence | denotes | Among them, 93 displayed the highest enzymatic inhibitory activity at SARS‐CoV‐1 Mpro. |
| T554 | 63871-63942 | Sentence | denotes | 169 However, no antiviral activity for this compound was communicated. |
| T555 | 63943-64012 | Sentence | denotes | The irreversible binding mode of 93 was confirmed by ESI‐MS analysis. |
| T556 | 64013-64023 | Sentence | denotes | 170 , 171 |
| T557 | 64024-64036 | Sentence | denotes | Ghosh et al. |
| T558 | 64037-64212 | Sentence | denotes | 172 studied the SARs of halopyridinyl indole carboxylates and identified a series of analogs (96–101; Figure 27) as SARS‐CoV‐1 Mpro inhibitors in the nanomolar potency range. |
| T559 | 64213-64332 | Sentence | denotes | The best derivative (100) had high enzymatic inhibitory potency (IC50, 0.030 µM) and antiviral activity (EC50, 6.9 µM). |
| T560 | 64333-64451 | Sentence | denotes | Compound 97 was also observed to inhibit the MERS‐CoV Mpro both in enzymatic and cell‐based (EC50, 12.5 µM) bioassays. |
| T561 | 64452-64538 | Sentence | denotes | 173 This molecule covalently modified Mpro, which was confirmed by MALDI‐TOF studies. |
| T562 | 64539-64621 | Sentence | denotes | Figure 27 SAR of halopyridinyl indole carboxylates as SARS‐CoV‐1 Mpro inhibitors. |
| T563 | 64622-64860 | Sentence | denotes | Mpro, main protease; SARS‐CoV, severe acute respiratory syndrome coronavirus 5‐Halopyridinyl esters are troublesome drug candidates because of their potential for rapid hydrolysis by various esterases and other enzymes in mammalian cells. |
| T564 | 64861-64971 | Sentence | denotes | They can potentially also react nonspecifically with other thiols and nucleophiles, a recipe for cytotoxicity. |
| T565 | 64972-65052 | Sentence | denotes | To bypass this problem by developing stable noncovalent inhibitors, Zhang et al. |
| T566 | 65053-65234 | Sentence | denotes | 174 reported a group of methylene ketones and analogous mono‐ and di‐fluorinated methylene ketones based on pyridinyl esters (102 and 103; Figure 28) as SARS‐CoV‐1 Mpro inhibitors. |
| T567 | 65235-65373 | Sentence | denotes | Enzymatic investigations and ESI‐MS experiments illustrate that those inhibitors bind to their target in a noncovalent, reversible manner. |
| T568 | 65374-65453 | Sentence | denotes | Figure 28 Etacrynic acid and isatin derivatives as SARS‐CoV‐1 Mpro inhibitors. |
| T569 | 65454-65696 | Sentence | denotes | Mpro, main protease; SARS‐CoV, severe acute respiratory syndrome coronavirus An HPLC‐based screening of electrophilic compounds identified the etacrynic acid‐derived amide 106 and ester 107 as SARS‐CoV‐1 Mpro inhibitors with moderate potency. |
| T570 | 65697-65938 | Sentence | denotes | 175 Etacrynic carboxamide (105; K i, 35.3 µM) bound more strongly to SARS‐CoV‐1 Mpro than to papain protease, while etacrynic acid ester 104 was more active at papain protease (K i, 3.2 µM) than at SARS‐CoV‐1 Mpro (K i, 45.8 µM; Figure 28). |
| T571 | 65939-66025 | Sentence | denotes | SAR studies suggested that chloro substituents were necessary for protease inhibition. |
| T572 | 66026-66165 | Sentence | denotes | Docking studies of 105 to Mpro revealed that it forms hydrogen bonds with Gln189, Glu166, Thr190, and Gln192 with its terminal amino group. |
| T573 | 66166-66287 | Sentence | denotes | The Michael system carbonyl group interacts with Gly143, and the reactive double bond remained next to the Cys145 sulfur. |
| T574 | 66288-66385 | Sentence | denotes | Previously, isatin (2,3‐dioxoindole) derivatives were observed to inhibit rhinovirus 3C protease. |
| T575 | 66386-66534 | Sentence | denotes | 176 Due to the structural similarity between the rhinovirus 3C protease and SARS‐CoV‐1 Mpro, these derivatives were tested against SARS‐CoV‐1 Mpro. |
| T576 | 66535-66674 | Sentence | denotes | Among them, 106 (IC50, 0.95 µM) and 107 (IC50, 0.98 µM) exhibited the best SARS‐CoV‐1 Mpro inhibitory activity in the low micromolar range. |
| T577 | 66675-66833 | Sentence | denotes | 176 SAR studies suggested that the inhibition efficiency was mainly reliant on hydrophobic and electronic properties of the isatin core substitution pattern. |
| T578 | 66834-66922 | Sentence | denotes | Docking studies revealed that the molecules fit well in the active site of the protease. |
| T579 | 66923-67027 | Sentence | denotes | Both carbonyl groups of the isatin core engaged in H‐bonds with NH of Gly143, Ser144, Cys145, and His41. |
| T580 | 67028-67250 | Sentence | denotes | Compounds 106 and 107 176 were more selective for SARS‐CoV‐1 Mpro than other proteases like papain (106, 103 µM; 107, 87.24 µM), chymotrypsin (106, ~1 mM; 107, 10.4 µM), and trypsin (106, 362 µM; 107, 243 µM; Figure 28). |
| T581 | 67251-67321 | Sentence | denotes | Zhou et al. extended the SAR studies for further activity improvement. |
| T582 | 67322-67407 | Sentence | denotes | Compound 108 bearing carboxamide showed the best SARS‐CoV‐1 Mpro inhibitory activity. |
| T583 | 67408-67498 | Sentence | denotes | However, this derivative did not bind covalently to the Cys145 residue of the active site. |
| T584 | 67499-67636 | Sentence | denotes | 177 Further structural investigations at the carboxamide of 108 with a variety of substituted sulfonamides did not improve the activity. |
| T585 | 67637-67694 | Sentence | denotes | Compound 109 was the best one of that series (Figure 28). |
| T586 | 67695-67698 | Sentence | denotes | 178 |
| T587 | 67699-67867 | Sentence | denotes | The modification of 110, identified by high‐throughput screening (HTS; Figure 29), led to pyrazolone and pyrazole derivatives 111 and 112 as SARS‐CoV‐1 Mpro inhibitors. |
| T588 | 67868-67919 | Sentence | denotes | 179 , 180 Taking these as leads, Ramajeyam et al. |
| T589 | 67920-68040 | Sentence | denotes | 181 reported compounds 112–114 to be the best‐performing inhibitors of the series(IC50 5.5, 6.8, 8.4 µM, respectively). |
| T590 | 68041-68108 | Sentence | denotes | They also observed moderate inhibitory activity against CVB3 3Cpro. |
| T591 | 68109-68273 | Sentence | denotes | Structure‐functionality analyses illustrated that the benzylidene ring next to pyrazolone C4 in addition to electron‐withdrawing groups, favors inhibitory activity. |
| T592 | 68274-68468 | Sentence | denotes | Molecular modeling studies of 112 predicted that for its inhibitory function, the N1‐phenyl residue in the Mpro S1 site as well as the carboxyl benzylidene moiety in the S3 pocket are important. |
| T593 | 68469-68536 | Sentence | denotes | Figure 29 Pyrazoles and pyrimidines as SARS‐CoV‐1 Mpro inhibitors. |
| T594 | 68537-68749 | Sentence | denotes | Mpro, main protease; SARS‐CoV, severe acute respiratory syndrome coronavirus Kumar et al. described furan‐inserted pyrazolone derivatives as dual SARS‐CoV‐1 Mpro and MERS‐CoV Mpro inhibitors (115–118; Figure 29). |
| T595 | 68750-68829 | Sentence | denotes | 182 Compounds 115, 117, and 118 exhibited the best dual inhibitory activities. |
| T596 | 68830-68947 | Sentence | denotes | Compounds 115 and 116 also displayed inhibitory activity against H5N1 neuraminidase (IC50 2.8, 2.9 µM, respectively). |
| T597 | 68948-69059 | Sentence | denotes | 183 Ramajeyam et al. also disclosed a range of pyrimidine derivatives as SARS‐CoV‐1 Mpro inhibitors (119–121). |
| T598 | 69060-69130 | Sentence | denotes | Compound 121 showed high inhibitory potency with an IC50 value 6.1 µM. |
| T599 | 69131-69134 | Sentence | denotes | 181 |
| T600 | 69135-69316 | Sentence | denotes | HTS of NIH molecular libraries (~293 000 substances) yielded the dipeptide 122 containing 3‐pyridyl as hit compound against SARS‐CoV‐1 Mpro with an IC50 value of 2.2 µM (Figure 30). |
| T601 | 69317-69411 | Sentence | denotes | Preliminary SAR studies identified 123 and 124 as the most promising inhibitors of the series. |
| T602 | 69412-69422 | Sentence | denotes | 184 , 185 |
| T603 | 69423-69493 | Sentence | denotes | Figure 30 Simple dipeptide derivatives as SARS‐CoV‐1 Mpro inhibitors. |
| T604 | 69494-69767 | Sentence | denotes | Mpro, main protease; SARS‐CoV, severe acute respiratory syndrome coronavirus The X‐ray crystal structure of 123 attached to SARS‐CoV‐1 Mpro highlighted the compound's identical orientation in the pocket to that of established covalent peptidomimetic inhibitors (Figure 31). |
| T605 | 69768-69853 | Sentence | denotes | The compound with an R‐configuration occupied the S3‐S1' subsites of SARS‐CoV‐1 Mpro. |
| T606 | 69854-70195 | Sentence | denotes | Indeed, only (R)‐123 was able to inhibit the Mpro enzyme with an IC50 value of 1.5 µM, while the (S)‐enantiomer was inactive. (R)‐123 inhibited SARS‐CoV‐1 Mpro in a competitive manner (K i, 1.6 µM) with a noncovalent mode of inhibition. (R)‐123 also showed antiviral activity (12.9 µM) in mock infected and SARS‐CoV‐1 infected Vero E6 cells. |
| T607 | 70196-70297 | Sentence | denotes | Figure 31 The X‐ray crystal structure of 123 bound to the binding pocket of SARS‐CoV‐1 Mpro (PDB ID: |
| T608 | 70298-70304 | Sentence | denotes | 3V3M). |
| T609 | 70305-70336 | Sentence | denotes | Pockets S1'–S3 are highlighted. |
| T610 | 70337-70660 | Sentence | denotes | Mpro, main protease; SARS‐CoV, severe acute respiratory syndrome coronavirus [Color figure can be viewed at wileyonlinelibrary.com] To enhance the inhibitory activity, SAR study efforts around P1' of 123 provided compounds containing imidazole (125) and 5‐chlorofuran (126) with equipotent activity to lead 123 (Figure 30). |
| T611 | 70661-70814 | Sentence | denotes | Next, the exploration of P1 3‐pyridyl unit of 123 revealed pyridazine (127) and pyrazine (128) which were only tolerated, albeit without any improvement. |
| T612 | 70815-71049 | Sentence | denotes | The same group of researchers discovered potent, noncovalent SARS‐CoV‐1 Mpro blockers based on a benzotriazole scaffold in an MLPCN screening, 186 resulting in hit compound 129 (Figure 32) with a SARS‐CoV‐1 Mpro IC50 value of 6.2 µM. |
| T613 | 71050-71126 | Sentence | denotes | Figure 32 SARS‐CoV‐1 Mpro inhibitors containing the benzotriazole scaffold. |
| T614 | 71127-71295 | Sentence | denotes | Mpro, main protease; SARS‐CoV, severe acute respiratory syndrome coronavirus SAR studies focusing on the benzotriazole moiety of 129 were performed to improve activity. |
| T615 | 71296-71417 | Sentence | denotes | The replacement of this group with 4‐phenyl‐1,2,3‐triazole (as in 130) was somewhat tolerated (IC50 of 11 µM; Figure 32). |
| T616 | 71418-71638 | Sentence | denotes | Further modifications to the acetamide (P2‐P1' region) resulted in molecules bearing a thiophene ring on one side and a branched i‐propyl amide (131) or cyclobutylamide (132) on the other—reaching IC50 values below 5 µM. |
| T617 | 71639-71772 | Sentence | denotes | To cut overall molecular weight of the inhibitors, P3‐truncation was performed, which led to potent derivatives (133–137; Figure 32). |
| T618 | 71773-71836 | Sentence | denotes | Compound 137 displayed extremely high inhibition (IC50, 51 nM). |
| T619 | 71837-71907 | Sentence | denotes | SARS‐CoV‐1 Mpro inhibitors were also discovered from medicinal plants. |
| T620 | 71908-71927 | Sentence | denotes | In 2011, Ryu et al. |
| T621 | 71928-72003 | Sentence | denotes | 187 disclosed a range of inhibitors obtained from Torreya nucifera leaves. |
| T622 | 72004-72157 | Sentence | denotes | Of all the isolated chemicals, the biflavone, amentoflavone (138; Figure 33), was identified as a potent noncompetitive inhibitor with an IC50 of 8.3 µM. |
| T623 | 72158-72259 | Sentence | denotes | Docking studies of 138 identified the interactions of Val186 and Gln192 as major sites at the target. |
| T624 | 72260-72356 | Sentence | denotes | Figure 33 Flavone and terpenoid derivatives with inhibitory activity against SARS‐CoV‐1 3CLpro. |
| T625 | 72357-72539 | Sentence | denotes | 3CLpro, 3C‐like protease; SARS‐CoV, severe acute respiratory syndrome coronavirus They also isolated a series of terpenoids from T. nucifera as anti‐SARS‐CoV Mpro agents (Figure 33). |
| T626 | 72540-72617 | Sentence | denotes | 187 Among them, ferruginol (139; IC50 49.6 µM) was the most active compound. |
| T627 | 72618-72859 | Sentence | denotes | Additionally, they isolated quinone‐methide triterpenoids celastrol (140), pritimererin (141), and tingenone (142) from methanol extracts of Tripterygium regelii which exhibited fair inhibition activity (IC50 2.6, 9.9, 5.5 µM, respectively). |
| T628 | 72860-72994 | Sentence | denotes | SAR studies indicated that for effective inhibition, the quinone‐methide group in ring A and the more lipophilic ring E were critical. |
| T629 | 72995-73077 | Sentence | denotes | All compounds were characterized as competitive inhibitors using kinetic analyses. |
| T630 | 73078-73088 | Sentence | denotes | Wen et al. |
| T631 | 73089-73187 | Sentence | denotes | 188 reported abietane‐type diterpenoids and lignoids with a powerful anti‐SARS‐CoV‐1 Mpro effect. |
| T632 | 73188-73323 | Sentence | denotes | Especially betulinic acid (143) and savinin (144) effectively inhibited SARS‐CoV‐1 Mpro (K i 8.2 µM, 9.1 µM, respectively) (Figure 33). |
| T633 | 73324-73371 | Sentence | denotes | These inhibitors acted in a competitive manner. |
| T634 | 73372-73560 | Sentence | denotes | Lu et al. discovered two hit SARS‐CoV‐1 3CLpro inhibitors, sulfone 145 and dihydroimidazole 146, by structure‐based virtual screening of a compound library of 58 855 chemicals (Figure 34). |
| T635 | 73561-73692 | Sentence | denotes | 189 The central structural elements of the hits, determined in docking experiments, were then used for additional analog searches. |
| T636 | 73693-73752 | Sentence | denotes | Figure 34 Structure of SARS‐CoV‐1 Mpro inhibitors 145–149. |
| T637 | 73753-73903 | Sentence | denotes | Mpro, main protease; SARS‐CoV, severe acute respiratory syndrome coronavirus Computational similarity screening discovered 21 analogs from these hits. |
| T638 | 73904-74001 | Sentence | denotes | Among them, the two best compounds 147 and 148 display IC50 values of 0.3 and 3 µM, respectively. |
| T639 | 74002-74119 | Sentence | denotes | A variety of SARS‐CoV‐1 Mpro inhibitors have been identified through virtual screening (VS) as an alternative to HTS. |
| T640 | 74120-74234 | Sentence | denotes | VS of 50 240 structurally diverse small molecules allowed to identify 104 molecules with anti‐SARS‐CoV‐1 activity. |
| T641 | 74235-74386 | Sentence | denotes | Compound 149 (Figure 34) demonstrated potent enzyme inhibition (IC50, 2.5 μM) and an EC50 of 7 μM in Vero cell‐based SARS‐CoV‐1 plaque reduction assays |
| T642 | 74387-74502 | Sentence | denotes | Virtual screening identified the serotonin antagonist cinanserin (150, Figure 35) as a potential inhibitor of Mpro. |
| T643 | 74503-74587 | Sentence | denotes | It had previously shown activity against SARS‐CoV‐1 Mpro with an IC50 value of 5 µM. |
| T644 | 74588-74710 | Sentence | denotes | 190 Subsequent tests revealed its anti‐SARS‐CoV‐2 activity (EC50, 20.6 µM) and an IC50 value of 125 µM (SARS‐CoV‐2 Mpro). |
| T645 | 74711-74755 | Sentence | denotes | Figure 35 Covalent bond inhibitors of Mpro. |
| T646 | 74756-74967 | Sentence | denotes | Mpro, main protease Their HTS yielded seven primary hits including the approved drugs disulfiram (151) and carmofur (152), as well as ebselen (153), shikonin (154), tideglusib (155), and PX‐12 (156) (Figure 35). |
| T647 | 74968-75122 | Sentence | denotes | Using MS/MS analysis, they deduced that ebselen (153) and 156 are irreversible inhibitors of Mpro by covalently attaching to Cys145 of the catalytic dyad. |
| T648 | 75123-75199 | Sentence | denotes | Molecular docking was used to illustrate how 151, 154, and 155 bind to Mpro. |
| T649 | 75200-75364 | Sentence | denotes | Antiviral activity assays, using real‐time reverse transcription‐PCR, indicated that ebselen and inhibitor “N3” (40; Figure 12) had the strongest antiviral effects. |
| T650 | 75365-75479 | Sentence | denotes | Ebselen displayed an EC50 value of 4.67 µM, and “N3” showed an EC50 value of 16.77 µM in a plaque‐reduction assay. |
| T651 | 75480-75545 | Sentence | denotes | Ebselen's IC50 value for SARS‐CoV‐2 Mpro was reported at 0.67 µM. |
| T652 | 75546-75614 | Sentence | denotes | The activity data of remaining compounds is summarized in Figure 35. |
| T653 | 75615-75693 | Sentence | denotes | Ebselen has been studied for an array of diseases and has a very low toxicity. |
| T654 | 75694-75765 | Sentence | denotes | 191 , 192 , 193 Its safety has been demonstrated in clinical trials. |
| T655 | 75766-75887 | Sentence | denotes | 191 , 192 , 194 It can therefore be considered a promising molecule for the treatment or prevention of CoV infections. |
| T656 | 75889-75922 | Sentence | denotes | 3.2 Coronavirus PLpro inhibitors |
| T657 | 75923-76051 | Sentence | denotes | Along with the Mpro, papain‐like protease (PLpro) also cleaves polyproteins which is an important process for viral replication. |
| T658 | 76052-76156 | Sentence | denotes | PLpro cleaves at the first three positions creating three nonstructural functional proteins (nsp1‐nsp3). |
| T659 | 76157-76240 | Sentence | denotes | In particular, nsp3 is central for the generation of the viral replication complex. |
| T660 | 76241-76451 | Sentence | denotes | The multifunctionality of PLpro in deubiquitinating, de‐ISGylation (ISG: interferon‐stimulated gene), 195 , 196 and in the evasion of the innate immune response make PLpro an attractive antiviral drug target. |
| T661 | 76452-76562 | Sentence | denotes | PLpro is a cysteine protease and its active site contains a catalytic triad composing of Cys112‐His273‐Asp287. |
| T662 | 76563-76630 | Sentence | denotes | Cys112 behaves as a nucleophile, and His273 is a general acid‐base. |
| T663 | 76631-76712 | Sentence | denotes | Asp287 helps His273 to align perfectly, thus promoting His to deprotonate Cys‐SH. |
| T664 | 76713-76725 | Sentence | denotes | Ghosh et al. |
| T665 | 76726-76841 | Sentence | denotes | 197 contributed significantly to the development of SARS‐CoV‐1 PLpro inhibitors based on the naphthalene scaffold. |
| T666 | 76842-76974 | Sentence | denotes | Two lead compounds 157 and 158 (Figure 36) were identified by an HTS of a chemical library containing greater than 50 000 compounds. |
| T667 | 76975-77071 | Sentence | denotes | They both inhibit PLpro of SARS‐CoV‐1 at a moderate potency (IC50 20.1 and 59 µM, respectively). |
| T668 | 77072-77222 | Sentence | denotes | The (R)‐enantiomer of compound 157 was found to be a greater than twofold more potent inhibitor of PLpro when compared with its racemic mixture (157). |
| T669 | 77223-77461 | Sentence | denotes | Subsequent SAR studies highlighted the 2‐naphthyl substitution as an important structural requirement rather than at the position 1 of the naphthyl ring in addition to the presence of o‐methyl and m‐amino groups, in the other phenyl ring. |
| T670 | 77462-77610 | Sentence | denotes | Compound 159 displayed the best inhibitory activity of PLpro (IC50, 0.6 µM) and acts in a noncovalent reversible manner with a K i value of 0.49 µM. |
| T671 | 77611-77713 | Sentence | denotes | 198 Compound 159 also showed moderate antiviral activity in Vero cells with an EC50 value of 14.5 µM. |
| T672 | 77714-77783 | Sentence | denotes | Figure 36 SARS‐CoV‐1 PLpro inhibitors based on naphthalene scaffold. |
| T673 | 77784-78021 | Sentence | denotes | PLpro, papain‐like protease; SARS‐CoV, severe acute respiratory syndrome coronavirus Compound 159 was further scrutinized by investigating the importance of the amide NH, and the effect of the substituent on the benzamide ring (160–164). |
| T674 | 78022-78208 | Sentence | denotes | Among them, compounds 163 and 164 exhibited the most potent enzymatic (163: IC50, 0.46 µM; 164: IC50, 1.23 µM) and cell‐based antiviral (163: EC50, 6.0 µM; 164: EC50, 5.2 µM) activities. |
| T675 | 78209-78272 | Sentence | denotes | Next, the same group studied the SARs for compound 158 further. |
| T676 | 78273-78433 | Sentence | denotes | This led to the discovery of compound 165 with high PLpro inhibitory activity of SARS‐CoV‐1 (IC50, 0.32 µM) and antiviral activity (EC50, 9.1 µM) in Vero cells. |
| T677 | 78434-78528 | Sentence | denotes | 199 The mode of action of 165 was found to be a noncovalent, competitive inhibition of PLpro. |
| T678 | 78529-78660 | Sentence | denotes | Unlike the previous series, the stereochemistry at the α‐methyl group did not make a significant difference in inhibition of PLpro. |
| T679 | 78661-78870 | Sentence | denotes | For example, both (S)‐ and (R)‐methyl inhibitors, 165 (IC50, 0.32 µM; EC50, 9.1 µM and 166 (IC50, 0.56 µM; EC50, 9.1 µM), respectively, shared equipotent inhibitory activity in enzymatic and cell‐based assays. |
| T680 | 78871-78941 | Sentence | denotes | Further SARs of 159 and 165 were investigated to improve the activity. |
| T681 | 78942-79081 | Sentence | denotes | However, no significant improvement in the activity was observed for the prepared compounds either in the enzymatic or cell‐based bioassay. |
| T682 | 79082-79153 | Sentence | denotes | Compounds 167–169 (Figure 36) displayed the best inhibitory activities. |
| T683 | 79154-79296 | Sentence | denotes | Especially, the m‐fluoro‐substituted benzamide derivative 168 (IC50, 0.15 µM; EC50, 5.4 µM) showed the best inhibition activity against PLpro. |
| T684 | 79297-79353 | Sentence | denotes | It also inhibited SARS‐CoV‐1 in the cell‐based bioassay. |
| T685 | 79354-79433 | Sentence | denotes | Both compounds 168 and 169 were metabolically more stable when compared to 167. |
| T686 | 79434-79593 | Sentence | denotes | HTS of a chemical library of 25000 molecules identified 170 (Figure 37) as a dual SARS‐CoV‐1 PLpro (IC50, 10.9 µM) and MERS‐CoV PLpro (IC50, 6.2 µM) inhibitor. |
| T687 | 79594-79724 | Sentence | denotes | 200 This compound acts via competitive inhibition against MERS‐CoV PLpro, yet via allosteric inhibition against SARS‐CoV‐1 PLpro. |
| T688 | 79725-79903 | Sentence | denotes | This compound also exhibited a preference for SARS‐CoV‐1 PLpro and MERS‐CoV PLpro versus two human homologs of the PLpro, ubiquitin C‐terminal hydrolase, (hUCH‐L1) and (hUCH‐L3). |
| T689 | 79904-79970 | Sentence | denotes | Figure 37 Broad spectral PLpro inhibitors from different sources. |
| T690 | 79971-80067 | Sentence | denotes | PLpro, papain‐like protease; SARS‐CoV, severe acute respiratory syndrome coronavirus Chou et al. |
| T691 | 80068-80211 | Sentence | denotes | 201 identified thiopurine (171) and 6‐thioguanine (172) as SARS‐CoV‐1 PLpro inhibitors by the screening of a library containing 160 compounds. |
| T692 | 80212-80270 | Sentence | denotes | The thiocarbonyl group was important for PLpro inhibition. |
| T693 | 80271-80373 | Sentence | denotes | However, the toxicity of these anticancer agents limits their therapeutic utility as anti‐SARS agents. |
| T694 | 80374-80394 | Sentence | denotes | In 2012, Park et al. |
| T695 | 80395-80498 | Sentence | denotes | 202 reported a tanshinone derivative 173 as a SARS‐CoV‐1 PLpro inhibitor with an IC50 value of 0.8 µM. |
| T696 | 80499-80581 | Sentence | denotes | The same research group also described diarylheptanoids blocking SARS‐CoV‐1 PLpro. |
| T697 | 80582-80688 | Sentence | denotes | In particular compound 174 performed as the best inhibitor of SARS‐CoV PLpro with an IC50 value of 4.1 µM. |
| T698 | 80689-80768 | Sentence | denotes | An α,β‐unsaturated carbonyl functionality was crucial for effective inhibition. |
| T699 | 80769-80915 | Sentence | denotes | The geranylated flavonoid 175 was another plant‐derived natural product, which displayed SARS‐CoV‐1 PLpro inhibition with an IC50 value of 5.0 µM. |
| T700 | 80916-80919 | Sentence | denotes | 203 |
| T701 | 80920-80940 | Sentence | denotes | In 2017, Park et al. |
| T702 | 80941-81010 | Sentence | denotes | 204 assessed the inhibitory activity of polyphenols isolated from B. |
| T703 | 81011-81064 | Sentence | denotes | Papyrifera against SARS‐CoV PLpro and MERS‐CoV PLpro. |
| T704 | 81065-81217 | Sentence | denotes | Two of them (176 and 177 Figure 37) displayed moderate inhibition at both SARS‐CoV‐1 PLpro and MERS‐CoV PLpro with a noncompetitive mechanism of action. |
| T705 | 81218-81452 | Sentence | denotes | Disulfiram (151; Figure 35) was also reported as a SARS‐CoV‐1 PLpro inhibitor (IC50, 24.1 µM), 205 probably by reacting with the active site cysteine, thereby covalently modifying the enzyme target, as was reported for other targets. |
| T706 | 81454-81480 | Sentence | denotes | 4 RdRP AND ITS INHIBITORS |
| T707 | 81481-81584 | Sentence | denotes | The ability to produce new RNA copies from available template molecules is necessary for life on earth. |
| T708 | 81585-81665 | Sentence | denotes | RNA polymerases are therefore found in all living cells as well as many viruses. |
| T709 | 81666-81781 | Sentence | denotes | RdRP are essential enzymes to all RNA viruses, as they catalyze the synthesis of new RNA from a given RNA template. |
| T710 | 81782-81968 | Sentence | denotes | 206 Due to their importance for viral life cycles, and their high conservation among different RNA viruses, they have been attractive drug targets for antiviral therapy for a long time. |
| T711 | 81969-82043 | Sentence | denotes | SARS‐CoV‐2 also uses an RdRP to replicate its genome within the host cell. |
| T712 | 82044-82170 | Sentence | denotes | Three nonstructural viral proteins (nsp) form its replication/transcription complex, with nsp12 forming the catalytic subunit. |
| T713 | 82171-82252 | Sentence | denotes | Bound to it are nsp7 and nsp8—accessory factors that facilitate template binding. |
| T714 | 82253-82341 | Sentence | denotes | 207 , 208 , 209 Their individual structures and that of the complex have been solved. |
| T715 | 82342-82515 | Sentence | denotes | 210 , 211 , 212 , 213 , 214 Interestingly, the only nsp that interacts directly with RNA seems to be nsp12, whereas nsp7 and nsp8 are needed to increase its efficiency. |
| T716 | 82516-82526 | Sentence | denotes | 210 , 215 |
| T717 | 82527-82658 | Sentence | denotes | RdRP is the target of inhibitors like remdesivir (178), galidesivir (179), ribavirin (180), favipiravir (181), and EIDD‐2801 (182). |
| T718 | 82659-82733 | Sentence | denotes | These molecules have shown promise for the treatment of COVID‐19 patients. |
| T719 | 82734-82809 | Sentence | denotes | 87 , 216 , 217 , 218 (For structures and biological data see Figure 38) |
| T720 | 82810-82956 | Sentence | denotes | Figure 38 Nucleoside analogs with inhibition activity against SARS‐CoV‐2 RdRP (adenosine, guanosine, and sofosbuvir are included for comparison). |
| T721 | 82957-83121 | Sentence | denotes | RdRP, RNA‐dependent RNA polymerase; SARS‐CoV, severe acute respiratory syndrome coronavirus Remdesivir is a 1'‐cyano‐substitued adenine C‐nucleoside analog prodrug. |
| T722 | 83122-83241 | Sentence | denotes | The prodrug strategy used is similar to that of the FDA‐approved anti‐hepatitis C drug sofosbuvir (183; see Figure 38). |
| T723 | 83242-83413 | Sentence | denotes | Upon its diffusion into cells, the phosphoramidate undergoes an intracellular conversion process that results in the formation of the triphosphate active metabolite (RTP). |
| T724 | 83414-83519 | Sentence | denotes | The triphosphate is recognized as adenine by viral RdRP, which causes heavy disruptions in RNA synthesis. |
| T725 | 83520-83634 | Sentence | denotes | The exact molecular mechanism of remdesivir's action against SARS‐CoV‐2 has recently been elucidated by Yin et al. |
| T726 | 83635-83765 | Sentence | denotes | 219 who reported cryo‐EM structures of SARS‐CoV‐2 RdRP with remdesivir monophosphate (RMP) covalently bound to the primer strand. |
| T727 | 83766-83910 | Sentence | denotes | As only a single RMP was incorporated in each observed primer strand the inhibition mechanism was shown to be nonobligate RNA chain termination. |
| T728 | 83911-84080 | Sentence | denotes | The addition of RTP led to a complete inhibition of RNA polymerization activity at a concentration of 1 mM, even in the presence of ATP in high concentrations of 100 mM. |
| T729 | 84081-84282 | Sentence | denotes | The authors further highlight the high conservation level of catalytic sites of RdRPs in different RNA viruses, which makes the discovery of future broad‐spectrum antiviral RdRP inhibitors seem likely. |
| T730 | 84283-84426 | Sentence | denotes | Remdesivir was previously reported to inhibit SARS‐CoV‐1 and MERS‐CoV replication in multiple in vitro systems, with submicromolar IC50 values. |
| T731 | 84427-84691 | Sentence | denotes | 220 In primary human airway epithelial (HAE) cell cultures, the antiviral activity assessment of remdesivir against SARS‐CoV‐1 and MERS‐CoV showed a dose‐dependent reduction in replication with average IC50 values of 0.069 µM (SARS‐CoV‐1) and 0.074 µM (MERS‐CoV). |
| T732 | 84692-84881 | Sentence | denotes | In a mouse model of SARS‐CoV‐1 pathogenesis, remdesivir greatly decreased the virus concentration in the lung and mitigated clinical symptoms of infection and restored respiratory function. |
| T733 | 84882-84950 | Sentence | denotes | Galidesivir is another C‐nucleoside analog that resembles adenosine. |
| T734 | 84951-85016 | Sentence | denotes | However, the base is not linked to a ribose, but to an aza‐sugar. |
| T735 | 85017-85143 | Sentence | denotes | Although it is recognized as adenosine by RdRP, its properties are different enough to cause a disruption in chain elongation. |
| T736 | 85144-85312 | Sentence | denotes | Galidesivir has been used in the treatment of Ebola and Marburg virus infections, and in vitro studies against SARS‐ and MERS‐CoVs have suggested efficacy against CoVs. |
| T737 | 85313-85421 | Sentence | denotes | 221 Therefore, it is a likely future anti SARS‐CoV‐2 agent, and currently being studied in clinical trials. |
| T738 | 85422-85432 | Sentence | denotes | 222 , 223 |
| T739 | 85433-85514 | Sentence | denotes | Ribavirin is a nucleoside analog, which shows structural similarity to guanosine. |
| T740 | 85515-85584 | Sentence | denotes | But guanosine's 6‐membered ring is only hinted at by the amide group. |
| T741 | 85585-85663 | Sentence | denotes | As such, it is incorporated by viral RdRPs, but interrupts RNA polymerization. |
| T742 | 85664-85757 | Sentence | denotes | 224 It is an approved drug in most countries and used against a variety of viral infections. |
| T743 | 85758-85920 | Sentence | denotes | Although its efficacy against SARS‐CoV‐2 has not been determined in large clinical trials, ribavirin has shown some promise in the treatment of COVID‐19 patients. |
| T744 | 85921-85924 | Sentence | denotes | 225 |
| T745 | 85925-86027 | Sentence | denotes | Favipiravir (Avigan®) is an approved antiviral drug for the treatment of influenza in Japan and China. |
| T746 | 86028-86122 | Sentence | denotes | It is a pyrazinamide derivative that has shown some activity against a variety of RNA viruses. |
| T747 | 86123-86190 | Sentence | denotes | 226 Favipiravir inhibits viral RdRP via its similarity to guanine. |
| T748 | 86191-86424 | Sentence | denotes | After biotransformation into its active metabolite, favipiravir‐ribofuranosyl‐5'‐triphosphate, it is incorporated into newly synthesized RNA by RdRP, leading to premature chain termination 227 similar to remdesivir's mode of action. |
| T749 | 86425-86520 | Sentence | denotes | Favipiravir is currently being studied around the world as a treatment option against COVID‐19. |
| T750 | 86521-86550 | Sentence | denotes | Very recently, Sheahan et al. |
| T751 | 86551-86638 | Sentence | denotes | 228 reported the discovery of EIDD‐1931 and its orally bioavailable prodrug EIDD‐2801. |
| T752 | 86639-86838 | Sentence | denotes | These nucleoside analogs have shown remarkable potency against SARS‐CoV‐2 and other related CoVs in vitro and in vivo, with IC50 values in the low nanomolar range, outperforming remdesivir 3–10‐fold. |
| T753 | 86839-86979 | Sentence | denotes | The reason for this increased potency could be additional interactions with viral RdRP involving the N4‐hydroxyl group of the cytidine ring. |
| T754 | 86980-87071 | Sentence | denotes | 219 The efficacy of EIDD‐2801 in COVID‐19 patients is being evaluated in a clinical trial. |
| T755 | 87072-87075 | Sentence | denotes | 229 |
| T756 | 87076-87311 | Sentence | denotes | Remdesivir and other potential RdRP inhibitors 230 are currently being studied in clinical trials around the world, but even though preliminary results appear promising, it is too early to assess their clinical value against COVID‐19. |
| T757 | 87313-87344 | Sentence | denotes | 5 DRUGS REPOSITIONING APPROACH |
| T758 | 87345-87495 | Sentence | denotes | Drug repurposing is an attractive strategy for finding new indications for already well‐established, marketed drugs or highly characterized compounds. |
| T759 | 87496-87660 | Sentence | denotes | It is a fast way to identify of new therapeutic options directly available for clinical use or eligible for accelerated approval for various diseases and disorders. |
| T760 | 87661-87758 | Sentence | denotes | An extensive effort has been made in repurposing approved drugs since the outbreak of SARS‐CoV‐1. |
| T761 | 87759-87864 | Sentence | denotes | Below, we summarize selected drug repositioning strategies for anticoronaviral therapy and their results. |
| T762 | 87865-87954 | Sentence | denotes | The host's innate interferon (IFN) response is one key for controlling viral replication. |
| T763 | 87955-88039 | Sentence | denotes | The IFN response can be increased by administering artificial IFNs and IFN inducers. |
| T764 | 88040-88135 | Sentence | denotes | The recombinant IFN‐α and ‐β inhibited the replication of SARS‐ and MERS‐CoVs in animal models. |
| T765 | 88136-88279 | Sentence | denotes | 231 Several studies also described the combination of IFNs with antiviral drugs like ribavirin (180) or lopinavir‐ritonavir for treating SARS. |
| T766 | 88280-88290 | Sentence | denotes | 232 , 233 |
| T767 | 88291-88513 | Sentence | denotes | In 2004, SARS patients in an open‐label study had better clinical outcomes when treated with ribavirin in combination with lopinavir‐ritonavir (400 and 100 mg, respectively) than the control group receiving only ribavirin. |
| T768 | 88514-88648 | Sentence | denotes | 227 A study in SARS patients found that viral replication could not be blocked at ribavirin concentrations achievable in human serum. |
| T769 | 88649-88777 | Sentence | denotes | 234 Nevertheless, the combination of ribavirin with IFN‐β had a synergistic effect on the inhibition of SARS‐CoV‐1 replication. |
| T770 | 88778-88887 | Sentence | denotes | The effects of PEGylated IFN together with ribavirin against SARS‐CoV‐2 are being studied in clinical trials. |
| T771 | 88888-88890 | Sentence | denotes | 87 |
| T772 | 88891-89027 | Sentence | denotes | Nitazoxanide (178; Figure 39), a broad‐spectrum antiparasitic drug, was reported to inhibit SARS‐CoV‐2 (EC50, 2.12 μM in Vero E6 cells). |
| T773 | 89028-89131 | Sentence | denotes | 215 It is also an IFN‐inducing agent, and it is being studied for treating a wide range of infections. |
| T774 | 89132-89224 | Sentence | denotes | Figure 39 Selected structures of drugs suitable for repositioning against SARS‐CoV‐1 and 2. |
| T775 | 89225-89394 | Sentence | denotes | SARS‐CoV, severe acute respiratory syndrome coronavirus The antiarrhythmic drug amiodarone (179, Figure 39) also inhibited SARS‐CoV‐1 replication in infected Vero cells. |
| T776 | 89395-89489 | Sentence | denotes | 235 The drug appears to alter the endocytotic pathway, thus inhibiting endosomal viral entry. |
| T777 | 89490-89618 | Sentence | denotes | Glycyrrhizin inhibited viral replication in Vero cells with an EC50 value of 300 mg/L, possibly by blocking viral entry as well. |
| T778 | 89619-89622 | Sentence | denotes | 232 |
| T779 | 89623-89826 | Sentence | denotes | As nitric oxide (NO) has been associated with antiviral activity, the NO donor, S‐nitroso‐N‐acetylpenicillamine (180; Figure 39) was reported to inhibit SARS‐CoV‐1 replication in a dose‐dependent manner. |
| T780 | 89827-89830 | Sentence | denotes | 236 |
| T781 | 89831-90089 | Sentence | denotes | In a search for potential antiviral agents against SARS‐CoV‐1, the screening of a library of 8000 approved drugs identified cinanserin (150; Figure 39), a serotonin antagonist, as a potential inhibitor of SARS‐CoV‐1 targeting its Mpro with IC50 value 4.0 µM. |
| T782 | 90090-90093 | Sentence | denotes | 189 |
| T783 | 90094-90227 | Sentence | denotes | A virtual screening and docking study identified the calmodulin antagonist calmidazolium as a SARS‐CoV‐1 Mpro inhibitor (K i, 61 µM). |
| T784 | 90228-90231 | Sentence | denotes | 237 |
| T785 | 90232-90424 | Sentence | denotes | In 2014, Dyall et al. reported an array of pharmaceutical drugs with antiviral activity against MERS‐CoV, and SARS‐CoV‐1 (Table 2, chemical structure of all drugs were indicated in Figure S1). |
| T786 | 90425-90489 | Sentence | denotes | 121 The agents were grouped according to their modes of action. |
| T787 | 90490-90528 | Sentence | denotes | Hits inhibited both investigated CoVs. |
| T788 | 90529-90599 | Sentence | denotes | Table 2 Compounds with inhibitory activity at MERS‐CoV and SARS‐CoV‐1 |
| T789 | 90600-90652 | Sentence | denotes | Drugs Class MERS‐CoVEC50 (µM) SARS‐CoV‐1EC50 (µM) |
| T790 | 90653-90695 | Sentence | denotes | Emetine Antibacterial agent 0.014 0.051 |
| T791 | 90696-90740 | Sentence | denotes | Chloroquine Antiparasitic agent 6.27 6.53 |
| T792 | 90741-90792 | Sentence | denotes | Hydroxychloroquine Antiparasitic agent 8.27 7.96 |
| T793 | 90793-90837 | Sentence | denotes | Mefloquine Antiparasitic agent 7.41 15.55 |
| T794 | 90838-90882 | Sentence | denotes | Amodiaquine Antiparasitic agent 6.21 1.27 |
| T795 | 90883-90925 | Sentence | denotes | Loperamide Antidiarrheal agent 4.8 5.90 |
| T796 | 90926-90963 | Sentence | denotes | Lopinavir HIV‐1 inhibitor 8.0 24.4 |
| T797 | 90964-91003 | Sentence | denotes | E‐64‐D Cathepsin inhibitor 1.27 0.76 |
| T798 | 91004-91053 | Sentence | denotes | Gemcitabine DNA metabolism inhibitor 1.21 4.95 |
| T799 | 91054-91106 | Sentence | denotes | Tamoxifen Estrogen receptor inhibitor 10.11 92.88 |
| T800 | 91107-91160 | Sentence | denotes | Toremifene Estrogen receptor inhibitor 12.91 11.96 |
| T801 | 91161-91215 | Sentence | denotes | Terconazole Sterol metabolism inhibitor 12.20 15.32 |
| T802 | 91216-91264 | Sentence | denotes | Triparanol Sterol metabolism inhibitor 5.28 ‐ |
| T803 | 91265-91318 | Sentence | denotes | Anisomycin Protein‐processing inhibitor 0.003 0.19 |
| T804 | 91319-91375 | Sentence | denotes | Cycloheximide Protein‐processing inhibitor 0.189 0.04 |
| T805 | 91376-91433 | Sentence | denotes | Homoharringtonine Protein‐processing inhibitor 0.071 ‐ |
| T806 | 91434-91487 | Sentence | denotes | Benztropine Neurotransmitter inhibitor 16.62 21.61 |
| T807 | 91488-91540 | Sentence | denotes | Fluspirilene Neurotransmitter inhibitor 7.47 5.96 |
| T808 | 91541-91592 | Sentence | denotes | Thiothixene Neurotransmitter inhibitor 9.29 5.31 |
| T809 | 91593-91648 | Sentence | denotes | Chlorpromazine Neurotransmitter inhibitor 9.51 12.97 |
| T810 | 91649-91702 | Sentence | denotes | Fluphenazine Neurotransmitter inhibitor 5.86 21.43 |
| T811 | 91703-91756 | Sentence | denotes | Promethazine Neurotransmitter inhibitor 11.80 7.54 |
| T812 | 91757-91807 | Sentence | denotes | Astemizole Neurotransmitter inhibitor 4.88 5.59 |
| T813 | 91808-91866 | Sentence | denotes | Chlorphenoxamine Neurotransmitter inhibitor 12.64 20.03 |
| T814 | 91867-91920 | Sentence | denotes | Thiethylperazine Neurotransmitter inhibitor 7.86 ‐ |
| T815 | 91921-91976 | Sentence | denotes | Triflupromazine Neurotransmitter inhibitor 5.75 6.39 |
| T816 | 91977-92030 | Sentence | denotes | Clomipramine Neurotransmitter inhibitor 9.33 13.23 |
| T817 | 92031-92080 | Sentence | denotes | Imatinib Kinase signaling inhibitor 17.68 9.82 |
| T818 | 92081-92130 | Sentence | denotes | Dasatinib Kinase signaling inhibitor 5.46 2.10 |
| T819 | 92131-92154 | Sentence | denotes | John Wiley & Sons, Ltd. |
| T820 | 92155-92279 | Sentence | denotes | This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. |
| T821 | 92280-92462 | Sentence | denotes | It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency. |
| T822 | 92463-92595 | Sentence | denotes | In particular, the protein‐processing inhibitors cycloheximide and anisomycin showed strong inhibitory activities against both CoVs. |
| T823 | 92596-92693 | Sentence | denotes | The HIV protease inhibitor lopinavir was more effective against SARS‐CoV‐1 than against MERS‐CoV. |
| T824 | 92694-92784 | Sentence | denotes | The antidiarrheal agent loperamide showed moderate inhibitory activitiy against both CoVs. |
| T825 | 92785-92914 | Sentence | denotes | The anti‐protozoal and emetic alkaloid with antibacterial properties, emetine, showed strong antiviral activity against MERS‐CoV. |
| T826 | 92915-93042 | Sentence | denotes | The antiparasitic drugs chloroquine, hydroxychloroquine, and mefloquine showed moderate antiviral activities against both CoVs. |
| T827 | 93043-93095 | Sentence | denotes | Cathepsin inhibitor, E‐64‐D, inhibited both as well. |
| T828 | 93096-93348 | Sentence | denotes | Two of the neurotransmitter inhibitors, chlorpromazine and triflupromazine also blocked both viruses (see Section 2) The DNA synthesis inhibitor gemcitabine was able to inhibit SARS‐CoV‐1 and MERS‐CoV with an EC50 value of 1.2 and 4.9 µM, respectively. |
| T829 | 93349-93481 | Sentence | denotes | Toremifene is an estrogen receptor 1 antagonist that inhibited both MERS‐CoV and SARS‐CoV‐1 (EC50, 12.9 and 11.97 µM, respectively). |
| T830 | 93482-93590 | Sentence | denotes | Kinase signaling pathway inhibitors imatinib and dasatinib were active against both MERS‐CoV and SARS‐CoV‐1. |
| T831 | 93591-93718 | Sentence | denotes | Imatinib was reported to act at an early stage of viral infection by hampering the fusion of viral particles with the endosome. |
| T832 | 93719-93721 | Sentence | denotes | 53 |
| T833 | 93722-93908 | Sentence | denotes | Niclosamide (181; Figure 39), an anthelmintic drug, exhibited very potent antiviral activity against SARS‐CoV‐1 replication and stopped viral antigen synthesis at 1.56 μM concentrations. |
| T834 | 93909-94074 | Sentence | denotes | 238 It prevented the cytopathic effect of SARS‐CoV‐1 at low concentrations of 1 μM and halted SARS‐CoV‐1 replication with an EC50 less than 0.1 μM in Vero E6 cells. |
| T835 | 94075-94285 | Sentence | denotes | 188 Gassen et al. demonstrated that niclosamide inhibits SKP2 activity, increases the lysine‐48‐linked polyubiquitination of the Benclin 1 level, boosts autophagy, and effectively impedes MERS‐CoV replication. |
| T836 | 94286-94375 | Sentence | denotes | 239 Niclosamide inhibited MERS‐CoV replication by up to 1000‐fold at 48 h p.i. at 10 μM. |
| T837 | 94376-94379 | Sentence | denotes | 239 |
| T838 | 94380-94527 | Sentence | denotes | Jeon et al. conducted a screening of FDA approved drugs in Vero cells to discover promising antiviral drug candidates against SARS‐CoV‐2 infection. |
| T839 | 94528-94629 | Sentence | denotes | 240 They reported 24 drugs that exhibited antiviral efficacy with IC50 values between 0.1 and 10 µM. |
| T840 | 94630-94793 | Sentence | denotes | Among them two approved drugs, niclosamide (181) and ciclesonide (182; Figure 39), exhibited notable inhibitory activities against virus replication in Vero cells. |
| T841 | 94794-94882 | Sentence | denotes | Niclosamide exhibited very potent antiviral activity against SARS‐CoV‐2 (IC50, 0.28 µM). |
| T842 | 94883-94974 | Sentence | denotes | The action of niclosamide might be attributed to autophagy as it was reported for MERS‐CoV. |
| T843 | 94975-95120 | Sentence | denotes | 239 Ciclesonide (182; Figure 39) is another interesting drug candidate with far lower antiviral potency (IC50, 4.33 µM) compared to niclosamide. |
| T844 | 95121-95192 | Sentence | denotes | It is a cortisol derivative used to treat asthma and allergic rhinitis. |
| T845 | 95193-95304 | Sentence | denotes | 241 A recent report by Matsuyama et al. confirmed ciclesonide as a possible antiviral drug against SARS‐CoV‐2. |
| T846 | 95305-95462 | Sentence | denotes | 242 A treatment report of three COVID‐19 patients (https://www3.nhk.or.jp/nhkworld/en/news/20200303_20/) merits further clinical investigation of this drug. |
| T847 | 95463-95571 | Sentence | denotes | The molecular target of ciclesonide's antiviral activity was revealed to be NSP15, a viral riboendonuclease. |
| T848 | 95572-95717 | Sentence | denotes | Together with its well‐established anti‐inflammatory effects, ciclesonide could offer an interesting option for the control of COVID‐19 symptoms. |
| T849 | 95718-95882 | Sentence | denotes | Azithromycin showed a synergistic effect in combination with hydroxychloroquine in vitro against SARS‐CoV‐2 at realistic concentrations reachable in the human lung. |
| T850 | 95883-95964 | Sentence | denotes | Clinical trials with this antibiotic were initiated in New York on 24 March 2020. |
| T851 | 95965-96073 | Sentence | denotes | 243 Very recently, however, the clinical benefit of the drug in COVID‐19 patients was called into question. |
| T852 | 96074-96076 | Sentence | denotes | 82 |
| T853 | 96077-96236 | Sentence | denotes | Studies for colchicine as an anti‐SARS‐CoV‐2 agent are currently ongoing with the aim of curtailing inflammation and lung complications in mild COVID‐19 cases. |
| T854 | 96237-96240 | Sentence | denotes | 244 |
| T855 | 96241-96338 | Sentence | denotes | Famotidine has been proposed as a therapeutic against COVID‐19, and a clinical trial is underway. |
| T856 | 96339-96428 | Sentence | denotes | 245 It is used to treat peptic ulcers and gastroesophageal reflux disease, among others. |
| T857 | 96429-96514 | Sentence | denotes | Cimetidine is a similar drug and has also been suggested as a treatment for COVID‐19. |
| T858 | 96515-96618 | Sentence | denotes | Dipyridamole was proposed as a treatment for COVID‐19 as well, and a clinical study is being conducted. |
| T859 | 96619-96707 | Sentence | denotes | 246 It is a nucleoside transport and PDE3 inhibitor that prevents blood clot formation. |
| T860 | 96708-96815 | Sentence | denotes | Sildenafil was proposed as treatment for COVID‐19, and it is currently being investigated in a small trial. |
| T861 | 96816-96911 | Sentence | denotes | 247 It is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. |
| T862 | 96912-96990 | Sentence | denotes | Fenofibrate and bezafibrate have been suggested for the treatment of COVID‐19. |
| T863 | 96991-97119 | Sentence | denotes | Fenofibrate is a blood lipid‐lowering medicine of the fibrate class. 248 , 249 Bezafibrate is a related lipid‐lowering agent. |
| T864 | 97120-97265 | Sentence | denotes | The HIV‐protease inhibitor nelfinavir (183; Figure 39) strongly inhibited replication of SARS‐CoV‐1 in Vero cells with an EC50 value of 0.048 µM. |
| T865 | 97266-97350 | Sentence | denotes | It was suggested to exert its effect at the post‐entry step of SARS‐CoV‐1 infection. |
| T866 | 97351-97539 | Sentence | denotes | 250 Recently, Yamamoto et al reported that nelfinavir also potently inhibited replication of SARS‐CoV‐2 among nine other Anti‐HIV drugs tested (IC50, 1.13 µM; CC50, 24.32 µM; SI = 21.52). |
| T867 | 97540-97651 | Sentence | denotes | 251 The measured serum concentrations of nelfinavir were 3–6 times higher than the reported EC50 of this drug. |
| T868 | 97652-97736 | Sentence | denotes | This indicates that it is a promising drug candidate for the management of COVID‐19. |
| T869 | 97737-97955 | Sentence | denotes | Other drugs tested against SARS‐CoV‐2 replication were amprenavir (EC50, 31.32 µM; CC50 > 81 µM; SI > 2.59), darunavir (EC50, 46.41 µM; CC50 > 81 µM; SI > 1.75), and indinavir (EC50, 59.14 µM; CC50 > 81 µM; SI > 1.37). |
| T870 | 97956-98051 | Sentence | denotes | Tipranavir inhibited SARS‐CoV‐2 replication as well (EC50, 3.34 µM; CC50, 76.80 µM; SI = 5.76). |
| T871 | 98052-98258 | Sentence | denotes | Ritonavir (EC50, 8.63 µM; CC50, 74.11 µM, SI = 8.59), saquinavir (EC50, 8.83 µM; CC50, 44.43 µM; SI = 5.03), and atazanavir (EC50, 9.36 µM; CC50 > 81 µM; SI > 8.65) suppressed SARS‐CoV‐2 at less than 10 µM. |
| T872 | 98259-98445 | Sentence | denotes | Lopinavir, which was studied in SARS and COVID‐19 patients, also potently inhibited SARS‐CoV‐2 replication with the highest selectivity index (EC50, 5.73 µM; CC50, 74.44 µM; SI = 12.99). |
| T873 | 98446-98638 | Sentence | denotes | De Wilde et al. identified four drugs—chloroquine (8), chlorpromazine (15), loperamide (184), and lopinavir (185)—by screening of an FDA approved drugs library (for structures, see Figure 40). |
| T874 | 98639-98794 | Sentence | denotes | 252 All of them blocked SARS‐CoV‐1, MERS‐CoV, and HCoV‐229E replication at small concentrations, suggesting potential as broad‐spectrum virostatic agents. |
| T875 | 98795-98857 | Sentence | denotes | Figure 40 Drugs repurposed for MERS‐ and SARS‐CoV infections. |
| T876 | 98858-99198 | Sentence | denotes | MERS, Middle East respiratory syndrome; SARS‐CoV, severe acute respiratory syndrome coronavirus Chloroquine (8) was able to inhibit SARS‐CoV‐2 viral replication in vitro, but a recent study found no clinical benefit for COVID‐19 patients who had received the drug 82 (the drug is discussed in detail in the section viral entry inhibitors). |
| T877 | 99199-99282 | Sentence | denotes | Chlorpromazine (15) stopped the replication of SARS‐CoV‐1, MERS‐CoV, and HCoV‐229E. |
| T878 | 99283-99396 | Sentence | denotes | It is a neuroleptic drug used against schizophrenia; 253 here, it interferes with clathrin‐mediated endocytosis. |
| T879 | 99397-99650 | Sentence | denotes | Since, clathrin‐mediated endocytosis is a crucial port for viral entry into the host cell, used by MHV, 254 , 255 , 256 SARS‐CoV‐1, 99 and MERS‐CoV, 102 future clinical trials could help elucidate this drug's therapeutic potential against COVID‐19. |
| T880 | 99651-99784 | Sentence | denotes | Loperamide (184), an opioid receptor agonist against diarrhea, 257 inhibited the replication of SARS‐CoV‐1, MERS‐CoV, and HCoV‐229E. |
| T881 | 99785-99880 | Sentence | denotes | Lopinavir (185) is an HIV protease inhibitor and was previously shown to block SARS‐CoV‐1 Mpro. |
| T882 | 99881-99884 | Sentence | denotes | 258 |
| T883 | 99885-100023 | Sentence | denotes | Shin et al. analyzed a library of 2334 approved medications and bioactive molecules to find possible antiviral compounds against MERS‐CoV. |
| T884 | 100024-100222 | Sentence | denotes | 259 A series of hit compounds was identified, categorized as anticancer (189, 190), antipsychotics (191, 192), and antidepressant (193) with inhibition activity between 2.1 and 14.4 µM (Figure 38). |
| T885 | 100223-100344 | Sentence | denotes | Saracatinib (189) was especially interesting, as it had remarkable anti‐MERS‐CoV activity (EC50 of 2.9 µM, CC50 > 50 µM). |
| T886 | 100345-100495 | Sentence | denotes | It is a small molecule drug with oral bioavailability used in the management of malignant neoplasms via Src‐family tyrosine kinases (SFKs) inhibition. |
| T887 | 100496-100638 | Sentence | denotes | It also suppressed other CoVs such as SARS‐CoV‐1 (EC50, 2.4 µM), HCoV‐229E (EC50, 5.1 µM), and FIPV (EC50, 7.0 µM) at nontoxic concentrations. |
| T888 | 100639-100693 | Sentence | denotes | Drugs 190 to 193 showed moderate antiviral activities. |
| T889 | 100695-100731 | Sentence | denotes | 6 Conclusions and future directions |
| T890 | 100732-100920 | Sentence | denotes | The SARS‐CoV‐2 outbreak has caused worldwide disruption and was recently declared a global pandemic by the World Health Organization (WHO) owing to its rapid spread and high fatality rate. |
| T891 | 100921-101017 | Sentence | denotes | As there is no effective treatment to date, the number of infections continues to rise globally. |
| T892 | 101018-101159 | Sentence | denotes | This has led numerous research groups around the world to prioritize the identification and development of new therapeutics against COVID‐19. |
| T893 | 101160-101328 | Sentence | denotes | Although it is often considered the most promising method to prevent or contain future coronavirus outbreaks, an all‐round anti‐CoV vaccine is possibly a long way away. |
| T894 | 101329-101425 | Sentence | denotes | Small molecule drugs have the potential to be effective, rapidly produced, and widely available. |
| T895 | 101426-101645 | Sentence | denotes | Indeed, several small molecules have been investigated and advanced to clinical trials for the treatment of COVID‐19, selected drug candidates are indicated in Table 3 (https://covid-19.heigit.org/clinical_trials.html). |
| T896 | 101646-101731 | Sentence | denotes | Table 3 Selection of molecules investigated in ongoing clinical studies (July, 2020) |
| T897 | 101732-101775 | Sentence | denotes | Name Structure Description Recent trials |
| T898 | 101776-101833 | Sentence | denotes | Azithromycin Macrolide antibiotic IRCT20200428047228N2 |
| T899 | 101834-101845 | Sentence | denotes | NCT04405921 |
| T900 | 101846-101868 | Sentence | denotes | EUCTR2020‐001605‐23‐ES |
| T901 | 101869-101925 | Sentence | denotes | Favipiravir Broad spectrum antiviral drug NCT04434248 |
| T902 | 101926-101942 | Sentence | denotes | ChiCTR2000033491 |
| T903 | 101943-101954 | Sentence | denotes | NCT04425460 |
| T904 | 101955-102016 | Sentence | denotes | Triazavirin Broad‐spectrum antiviral drug ChiCTR2000030001 |
| T905 | 102017-102066 | Sentence | denotes | Umifenovir Antiviral drug IRCT20200523047550N1 |
| T906 | 102067-102088 | Sentence | denotes | IRCT20151227025726N15 |
| T907 | 102089-102109 | Sentence | denotes | IRCT20200325046859N2 |
| T908 | 102110-102163 | Sentence | denotes | Baloxavir marboxil Antiviral drug ChiCTR2000029548 |
| T909 | 102164-102180 | Sentence | denotes | ChiCTR2000029544 |
| T910 | 102181-102221 | Sentence | denotes | Remdesivir Antiviral drug NCT04431453 |
| T911 | 102222-102233 | Sentence | denotes | NCT04409262 |
| T912 | 102234-102245 | Sentence | denotes | NCT04410354 |
| T913 | 102246-102294 | Sentence | denotes | Ribavirin Antiviral drug IRCT20200324046850N2 |
| T914 | 102295-102311 | Sentence | denotes | ChiCTR2000030922 |
| T915 | 102312-102378 | Sentence | denotes | Lopinavir/ritonavir Anti‐HIV combination medication NCT04403100 |
| T916 | 102379-102390 | Sentence | denotes | NCT04376814 |
| T917 | 102391-102442 | Sentence | denotes | Celecoxib COX‐2 selective NSAID ChiCTR2000031630 |
| T918 | 102443-102498 | Sentence | denotes | Chloroquine Antimalarial drug EUCTR2020‐001441‐39‐IT |
| T919 | 102499-102510 | Sentence | denotes | NCT04447534 |
| T920 | 102511-102522 | Sentence | denotes | NCT04443270 |
| T921 | 102523-102585 | Sentence | denotes | Hydroxychloroquine Antimalarial drug EUCTR2020‐001558‐23‐IT |
| T922 | 102586-102608 | Sentence | denotes | EUCTR2020‐001441‐39‐IT |
| T923 | 102609-102631 | Sentence | denotes | EUCTR2020‐001501‐24‐IT |
| T924 | 102632-102686 | Sentence | denotes | Mefloquine Antimalarial drug EUCTR2020‐001194‐69‐ES |
| T925 | 102687-102746 | Sentence | denotes | Ivermectin Broad‐spectrum antiparasitic drug NCT04445311 |
| T926 | 102747-102758 | Sentence | denotes | NCT04435587 |
| T927 | 102759-102770 | Sentence | denotes | NCT04431466 |
| T928 | 102771-102834 | Sentence | denotes | Colchicine Broad‐spectrum anti‐inflammatory drug NCT04416334 |
| T929 | 102835-102857 | Sentence | denotes | EUCTR2020‐001841‐38‐ES |
| T930 | 102858-102878 | Sentence | denotes | IRCT20190810044500N5 |
| T931 | 102879-102965 | Sentence | denotes | Corticosteroids (misc.) Broad‐spectrum anti‐inflammatory drug IRCT20151227025726N17 |
| T932 | 102966-102977 | Sentence | denotes | NCT04395105 |
| T933 | 102978-103000 | Sentence | denotes | IRCT20120215009014N354 |
| T934 | 103001-103073 | Sentence | denotes | Pirfenidone Antifibrotic, anti‐inflammatory drug IRCT20200314046764N1 |
| T935 | 103074-103090 | Sentence | denotes | ChiCTR2000031138 |
| T936 | 103091-103143 | Sentence | denotes | Tranilast Anti‐inflammatory drug ChiCTR2000030002 |
| T937 | 103144-103184 | Sentence | denotes | Selinexor Anticancer drug NCT04355676 |
| T938 | 103185-103196 | Sentence | denotes | NCT04349098 |
| T939 | 103197-103219 | Sentence | denotes | EUCTR2020‐001411‐25‐GB |
| T940 | 103220-103280 | Sentence | denotes | Valsartan Angiotensin II receptor antagonist DRKS00021732 |
| T941 | 103281-103292 | Sentence | denotes | NCT04335786 |
| T942 | 103293-103347 | Sentence | denotes | Dipyridamole PDE3 inhibitor NCT04424901 NCT04391179 |
| T943 | 103348-103417 | Sentence | denotes | Vidoflumidus (IMU‐838) Investigational drug EUCTR2020‐001264‐28‐HU |
| T944 | 103418-103472 | Sentence | denotes | Azvudine Investigational antiviral ChiCTR2000032769 |
| T945 | 103473-103484 | Sentence | denotes | NCT04425772 |
| T946 | 103485-103501 | Sentence | denotes | ChiCTR2000030487 |
| T947 | 103502-103552 | Sentence | denotes | EIDD‐2801 Investigational antiviral NCT04405570 |
| T948 | 103553-103564 | Sentence | denotes | NCT04405739 |
| T949 | 103565-103576 | Sentence | denotes | NCT04392219 |
| T950 | 103577-103600 | Sentence | denotes | John Wiley & Sons, Ltd. |
| T951 | 103601-103725 | Sentence | denotes | This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. |
| T952 | 103726-103908 | Sentence | denotes | It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency. |
| T953 | 103909-104092 | Sentence | denotes | As outlined in this review, inhibitors of important viral enzymes or structures, such as Mpro, PLpro, or RdRP have displayed encouraging activity against various human‐infecting CoVs. |
| T954 | 104093-104361 | Sentence | denotes | Since, both contagious viruses, SARS‐CoV‐1 and SARS‐CoV‐2, have a similar mechanism of infection; and both share the same human receptor, ACE2, for viral entry, for example—already developed inhibitors against the former could potentially be used to combat the latter. |
| T955 | 104362-104506 | Sentence | denotes | But despite the efficacy demonstrated by many inhibitors of SARS‐CoV‐1, no specific prophylactic or postexposure therapy is currently available. |
| T956 | 104507-104565 | Sentence | denotes | The first step in the viral life cycle is the viral entry. |
| T957 | 104566-104690 | Sentence | denotes | It represents an attractive intervention point by blocking the RBD‐ACE2 interaction or the virus‐cell membrane fusion event. |
| T958 | 104691-104843 | Sentence | denotes | A large number of inhibitors, including peptides, antibodies, small‐molecule compounds, and natural products have been identified to hamper viral entry. |
| T959 | 104844-105025 | Sentence | denotes | Some of the peptides and antibodies displayed substantial anti‐SARS activity and are therefore considered promising entry inhibitors with high potencies in the low micromolar range. |
| T960 | 105026-105146 | Sentence | denotes | Despite the apparent match of SARS‐CoV‐2 S and ACE2, other possible viral entry receptors should not be left unexplored. |
| T961 | 105147-105388 | Sentence | denotes | The glucose‐regulated protein 78 (GRP‐78, aka HSPA5), for instance, is employed as a coreceptor for entry by several viruses, including bat‐CoVs and MERS‐CoV, 260 and a study predicted that SARS‐CoV‐2 S might utilize this mechanism as well. |
| T962 | 105389-105470 | Sentence | denotes | 261 Elevated levels of GRP‐78 in COVID‐19 patients suggest a supplementary link. |
| T963 | 105471-105608 | Sentence | denotes | 262 Although as of yet unconfirmed, the development of therapeutics against additional targets like GRP‐78 should receive due attention. |
| T964 | 105609-105768 | Sentence | denotes | Viral proteases are another very important target for the development of antiviral therapies, as they are directly involved in the viral replication processes. |
| T965 | 105769-105947 | Sentence | denotes | Especially the Mpro is one of the best‐characterized viral targets, and numerous medicinal chemistry efforts have been already reported for the past outbreaks of SARS‐1 and MERS. |
| T966 | 105948-106066 | Sentence | denotes | Main proteases are highly conserved among other CoVs, which allows the development of broad spectral antiviral agents. |
| T967 | 106067-106123 | Sentence | denotes | Moreover, no human protease analog to the Mpro is known. |
| T968 | 106124-106192 | Sentence | denotes | Thus, drugs targeting Mpro could be highly virus‐selective and safe. |
| T969 | 106193-106365 | Sentence | denotes | In light of the urgency of the current outbreak, repositioning of already approved drugs is becoming a popular approach due to the availability of toxicity and safety data. |
| T970 | 106366-106458 | Sentence | denotes | Drug repurposing has become fashionable, promising quick solutions to complicated questions. |
| T971 | 106459-106520 | Sentence | denotes | Old and, presumably, safe drugs are proclaimed miracle cures. |
| T972 | 106521-106552 | Sentence | denotes | The reality is a different one: |
| T973 | 106553-106765 | Sentence | denotes | Widely employed broad‐spectrum antiviral drugs, such as (hydroxy)chloroquine, favipiravir, ribavirin, or umifenovir were reported to be effective against SARS‐CoV‐2, but could not convince in clinical trials yet. |
| T974 | 106766-106880 | Sentence | denotes | Clinicians are faced with an avalanche of contraindications and a myriad of case reports to choose the right drug. |
| T975 | 106881-106966 | Sentence | denotes | The drug repositioning strategy is, therefore, not a sound scientific path to a cure. |
| T976 | 106967-107100 | Sentence | denotes | At best, it can provide a basis for extensive future research in all related fields, including synthetic organic medicinal chemistry. |
| T977 | 107101-107201 | Sentence | denotes | A new problem with the current COVID‐19 outbreak is related to the spread of scientific information. |
| T978 | 107202-107395 | Sentence | denotes | When initial unfounded speculations about the alleged dangers of antihypertensive therapies with ACEis and ARBs were widely publicized in the media they caused great uncertainty among patients. |
| T979 | 107396-107505 | Sentence | denotes | Impetuous communications such as these can have serious consequences and should not be proclaimed carelessly. |
| T980 | 107506-107641 | Sentence | denotes | As it turns out, the benefits of continued antihypertensive therapy with these medicines in COVID‐19 patients far outweigh their risks. |
| T981 | 107642-107799 | Sentence | denotes | There is even evidence of additional protective effects of ACEis and ARBs in this cohort, although the clinical relevance of this has yet to be investigated. |
| T982 | 107800-107989 | Sentence | denotes | It is clear that governments and societies all over the world have been surprised by the recent coronavirus outbreak—as they were by the SARS outbreak in 2003 and the MERS epidemic in 2013. |
| T983 | 107990-108078 | Sentence | denotes | Human‐infecting CoVs are on the rise, but quickly forgotten once life returns to normal. |
| T984 | 108079-108164 | Sentence | denotes | However, this problem will not disappear by itself, but likely increase in intensity. |
| T985 | 108165-108271 | Sentence | denotes | Viral spillover events are expected to increase in frequency as humans continue to invade new territories. |
| T986 | 108272-108416 | Sentence | denotes | We hope that, this time, the world will heed nature's warning to finance and conduct groundbreaking research on CoVs and their disease patterns. |
| T987 | 108417-108554 | Sentence | denotes | Only with a profound understanding of the viral life cycle and the affected human physiology we can prevent and control future outbreaks. |
| T988 | 108556-108577 | Sentence | denotes | CONFLICT OF INTERESTS |
| T989 | 108578-108631 | Sentence | denotes | The authors declare there is no conflict of interest. |
| T990 | 108633-108654 | Sentence | denotes | AUTHORS CONTRIBUTIONS |
| T991 | 108655-108694 | Sentence | denotes | TP, LLW, MM, and ME collected the data. |
| T992 | 108695-108745 | Sentence | denotes | TP wrote the manuscript, which was revised by all. |
| T993 | 108747-108769 | Sentence | denotes | Supporting information |
| T994 | 108770-108793 | Sentence | denotes | Supporting information. |
| T995 | 108794-108830 | Sentence | denotes | Click here for additional data file. |
| T996 | 108832-108847 | Sentence | denotes | ACKNOWLEDGMENTS |
| T997 | 108848-108908 | Sentence | denotes | Manoj Manickam thanks PSG managementfor their moral support. |
| T998 | 108909-108967 | Sentence | denotes | Open access funding enabled and organized by Projekt DEAL. |
| T999 | 108969-109147 | Sentence | denotes | Thanigaimalai Pillaiyar received his doctoral degree in Medicinal Chemistry in 2011 under the supervision of Prof. Dr. Sang‐Hun Jung at Chungnam National University, South Korea. |
| T1000 | 109148-109344 | Sentence | denotes | In 2011, he won a “Japanese Society for the Promotion of Science Postdoctoral Fellowship (JSPS)” for 2 years with Prof. Dr. Yoshio Hayashi at Tokyo University of Pharmacy and Life Sciences, Japan. |
| T1001 | 109345-109461 | Sentence | denotes | He was awarded an Alexander von Humboldt postdoctoral fellowship (AvH) in 2013 for 2 years with Prof. Dr. Christa E. |
| T1002 | 109462-109500 | Sentence | denotes | Müller at University of Bonn, Germany. |
| T1003 | 109501-109557 | Sentence | denotes | He worked as a visiting scientist at the Prof. Steven V. |
| T1004 | 109558-109629 | Sentence | denotes | Ley's Laboratory, Department of Chemistry, and University of Cambridge. |
| T1005 | 109630-109750 | Sentence | denotes | Currently he is working on developing modulators/inhibitors for SARS‐CoV‐2 Mpro and various G‐protein‐coupled receptors. |
| T1006 | 109751-109759 | Sentence | denotes | Lukas L. |
| T1007 | 109760-109824 | Sentence | denotes | Wendt is a PhD student in the research group of Prof. Christa E. |
| T1008 | 109825-109867 | Sentence | denotes | Müller at the University of Bonn, Germany. |
| T1009 | 109868-109936 | Sentence | denotes | He studied Pharmacy at the University of Frankfurt am Main, Germany. |
| T1010 | 109937-110170 | Sentence | denotes | In 2016, he started his PhD in a Medicinal Chemistry PhD program at the University of Bonn, where he is working on the design and preparation of small molecule ligands for G protein‐coupled receptors with immunomodulatory properties. |
| T1011 | 110171-110258 | Sentence | denotes | He is actively involved in teaching students of medicinal and pharmaceutical chemistry. |
| T1012 | 110259-110345 | Sentence | denotes | Manoj Manickam received his PhD in 2010 from Bharathiar University, Coimbatore, India. |
| T1013 | 110346-110435 | Sentence | denotes | He continued to work as a Research Associate at Orchid Chemicals and Pharmaceuticals Ltd. |
| T1014 | 110436-110607 | Sentence | denotes | Then he moved to Chungam National University, South Korea, to continue his research as Postdoctoral Researcher and Research Professor working with Professor Sang‐Hun Jung. |
| T1015 | 110608-110758 | Sentence | denotes | Currently, he is working in PSG Institute of Technology and Applied Research, Coimbatore, India as Assistant Professor in the Department of Chemistry. |
| T1016 | 110759-110900 | Sentence | denotes | He is actively involved in the preparation of small molecules for various therapeutic targets such as heart failure, hypertension and cancer. |
| T1017 | 110901-111075 | Sentence | denotes | Maheswaran Easwaran received his doctoral degree in veterinary medicine in 2016 under the supervision of Prof. Dr. Hyun‐Jin Shin at Chungnam National University, South Korea. |
| T1018 | 111076-111158 | Sentence | denotes | He continued his research as a postdoctoral researcher in the same lab for 1 year. |
| T1019 | 111159-111292 | Sentence | denotes | Then, he moved to Kangwon National University, South Korea, to continue his research as a senior researcher with Prof. Dr. Juhee Ahn. |
| T1020 | 111293-111444 | Sentence | denotes | Presently, he is working at the Sethu Institute of Technology, Virudhunagar, India, as Assistant Professor in the Department of Biomedical Engineering. |
| T1021 | 111445-111539 | Sentence | denotes | He is actively involved to combat multidrug resistant bacterial pathogens using phage therapy. |