PMC:7456455 / 32050-32455 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T399","span":{"begin":59,"end":80},"obj":"Body_part"},{"id":"T400","span":{"begin":187,"end":209},"obj":"Body_part"},{"id":"T401","span":{"begin":235,"end":240},"obj":"Body_part"},{"id":"T402","span":{"begin":254,"end":261},"obj":"Body_part"},{"id":"T403","span":{"begin":306,"end":315},"obj":"Body_part"},{"id":"T404","span":{"begin":320,"end":326},"obj":"Body_part"},{"id":"T405","span":{"begin":327,"end":338},"obj":"Body_part"}],"attributes":[{"id":"A399","pred":"fma_id","subj":"T399","obj":"http://purl.org/sig/ont/fma/fma273563"},{"id":"A400","pred":"fma_id","subj":"T400","obj":"http://purl.org/sig/ont/fma/fma273563"},{"id":"A401","pred":"fma_id","subj":"T401","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A402","pred":"fma_id","subj":"T402","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A403","pred":"fma_id","subj":"T403","obj":"http://purl.org/sig/ont/fma/fma62864"},{"id":"A404","pred":"fma_id","subj":"T404","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A405","pred":"fma_id","subj":"T405","obj":"http://purl.org/sig/ont/fma/fma63261"}],"text":"6 OUTSTANDING questions\n1. Define the molecular basis for mononuclear phagocyte contributions to different stages of COVID-19 resistance and pathogenesis.\n2. Define interactions between mononuclear phagocytes, COVID-19 and other host cells in different tissues.\n3. Develop tests to quantify biomarkers of monocytes and tissue macrophages during COVID-19, for diagnosis, prognosis, therapy and prevention."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T89","span":{"begin":320,"end":326},"obj":"Body_part"}],"attributes":[{"id":"A89","pred":"uberon_id","subj":"T89","obj":"http://purl.obolibrary.org/obo/UBERON_0000479"}],"text":"6 OUTSTANDING questions\n1. Define the molecular basis for mononuclear phagocyte contributions to different stages of COVID-19 resistance and pathogenesis.\n2. Define interactions between mononuclear phagocytes, COVID-19 and other host cells in different tissues.\n3. Develop tests to quantify biomarkers of monocytes and tissue macrophages during COVID-19, for diagnosis, prognosis, therapy and prevention."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T199","span":{"begin":118,"end":126},"obj":"Disease"},{"id":"T200","span":{"begin":211,"end":219},"obj":"Disease"},{"id":"T201","span":{"begin":346,"end":354},"obj":"Disease"}],"attributes":[{"id":"A199","pred":"mondo_id","subj":"T199","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A200","pred":"mondo_id","subj":"T200","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A201","pred":"mondo_id","subj":"T201","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"6 OUTSTANDING questions\n1. Define the molecular basis for mononuclear phagocyte contributions to different stages of COVID-19 resistance and pathogenesis.\n2. Define interactions between mononuclear phagocytes, COVID-19 and other host cells in different tissues.\n3. Develop tests to quantify biomarkers of monocytes and tissue macrophages during COVID-19, for diagnosis, prognosis, therapy and prevention."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T449","span":{"begin":59,"end":80},"obj":"http://purl.obolibrary.org/obo/CL_0000113"},{"id":"T450","span":{"begin":187,"end":209},"obj":"http://purl.obolibrary.org/obo/CL_0000113"},{"id":"T451","span":{"begin":235,"end":240},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T452","span":{"begin":274,"end":279},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T453","span":{"begin":306,"end":315},"obj":"http://purl.obolibrary.org/obo/CL_0000576"}],"text":"6 OUTSTANDING questions\n1. Define the molecular basis for mononuclear phagocyte contributions to different stages of COVID-19 resistance and pathogenesis.\n2. Define interactions between mononuclear phagocytes, COVID-19 and other host cells in different tissues.\n3. Develop tests to quantify biomarkers of monocytes and tissue macrophages during COVID-19, for diagnosis, prognosis, therapy and prevention."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T143","span":{"begin":142,"end":154},"obj":"http://purl.obolibrary.org/obo/GO_0009405"}],"text":"6 OUTSTANDING questions\n1. Define the molecular basis for mononuclear phagocyte contributions to different stages of COVID-19 resistance and pathogenesis.\n2. Define interactions between mononuclear phagocytes, COVID-19 and other host cells in different tissues.\n3. Develop tests to quantify biomarkers of monocytes and tissue macrophages during COVID-19, for diagnosis, prognosis, therapy and prevention."}

{"project":"LitCovid-sentences","denotations":[{"id":"T190","span":{"begin":0,"end":24},"obj":"Sentence"},{"id":"T191","span":{"begin":25,"end":27},"obj":"Sentence"},{"id":"T192","span":{"begin":28,"end":155},"obj":"Sentence"},{"id":"T193","span":{"begin":156,"end":158},"obj":"Sentence"},{"id":"T194","span":{"begin":159,"end":262},"obj":"Sentence"},{"id":"T195","span":{"begin":263,"end":265},"obj":"Sentence"},{"id":"T196","span":{"begin":266,"end":405},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"6 OUTSTANDING questions\n1. Define the molecular basis for mononuclear phagocyte contributions to different stages of COVID-19 resistance and pathogenesis.\n2. Define interactions between mononuclear phagocytes, COVID-19 and other host cells in different tissues.\n3. Develop tests to quantify biomarkers of monocytes and tissue macrophages during COVID-19, for diagnosis, prognosis, therapy and prevention."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T824","span":{"begin":59,"end":70},"obj":"GO:0005634;CL:0000113"},{"id":"T825","span":{"begin":71,"end":80},"obj":"CL:0000113"},{"id":"T826","span":{"begin":118,"end":126},"obj":"SP_7"},{"id":"T827","span":{"begin":187,"end":198},"obj":"GO:0005634;CL:0000113"},{"id":"T828","span":{"begin":199,"end":209},"obj":"CL:0000113"},{"id":"T829","span":{"begin":211,"end":219},"obj":"SP_7"},{"id":"T830","span":{"begin":254,"end":261},"obj":"UBERON:0000479"},{"id":"T831","span":{"begin":306,"end":315},"obj":"CL:0000576"},{"id":"T832","span":{"begin":320,"end":326},"obj":"UBERON:0000479"},{"id":"T833","span":{"begin":327,"end":338},"obj":"CL:0000235"},{"id":"T834","span":{"begin":346,"end":354},"obj":"SP_7"},{"id":"T1020","span":{"begin":187,"end":198},"obj":"GO:0005634;CL:0000113"},{"id":"T45658","span":{"begin":199,"end":209},"obj":"CL:0000113"},{"id":"T835","span":{"begin":59,"end":70},"obj":"GO:0005634;CL:0000113"},{"id":"T836","span":{"begin":71,"end":80},"obj":"CL:0000113"},{"id":"T837","span":{"begin":118,"end":126},"obj":"SP_7"},{"id":"T838","span":{"begin":187,"end":198},"obj":"GO:0005634;CL:0000113"},{"id":"T839","span":{"begin":199,"end":209},"obj":"CL:0000113"},{"id":"T840","span":{"begin":211,"end":219},"obj":"SP_7"},{"id":"T841","span":{"begin":254,"end":261},"obj":"UBERON:0000479"},{"id":"T842","span":{"begin":306,"end":315},"obj":"CL:0000576"},{"id":"T843","span":{"begin":320,"end":326},"obj":"UBERON:0000479"},{"id":"T844","span":{"begin":327,"end":338},"obj":"CL:0000235"},{"id":"T845","span":{"begin":346,"end":354},"obj":"SP_7"}],"text":"6 OUTSTANDING questions\n1. Define the molecular basis for mononuclear phagocyte contributions to different stages of COVID-19 resistance and pathogenesis.\n2. Define interactions between mononuclear phagocytes, COVID-19 and other host cells in different tissues.\n3. Develop tests to quantify biomarkers of monocytes and tissue macrophages during COVID-19, for diagnosis, prognosis, therapy and prevention."}

{"project":"LitCovid-PubTator","denotations":[{"id":"723","span":{"begin":118,"end":126},"obj":"Disease"},{"id":"725","span":{"begin":211,"end":219},"obj":"Disease"},{"id":"727","span":{"begin":346,"end":354},"obj":"Disease"}],"attributes":[{"id":"A723","pred":"tao:has_database_id","subj":"723","obj":"MESH:C000657245"},{"id":"A725","pred":"tao:has_database_id","subj":"725","obj":"MESH:C000657245"},{"id":"A727","pred":"tao:has_database_id","subj":"727","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"6 OUTSTANDING questions\n1. Define the molecular basis for mononuclear phagocyte contributions to different stages of COVID-19 resistance and pathogenesis.\n2. Define interactions between mononuclear phagocytes, COVID-19 and other host cells in different tissues.\n3. Develop tests to quantify biomarkers of monocytes and tissue macrophages during COVID-19, for diagnosis, prognosis, therapy and prevention."}