PMC:7456455 / 30162-31553 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/7456455","sourcedb":"PMC","sourceid":"7456455","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7456455","text":"Separate streams of the mononuclear phagocyte lineage co-exist to generate monocytic, granulocytic and dendritic cell-like monocytes [78], and the impact of COVID-19 infection on monocyte activation needs to be determined to identify targets for diagnosis and intervention. The different monocytic lineage receptors for CSF1, 2 and 3 provide direct markers of disturbed haematopoiesis and skewed cell differentiation [79]; and can be combined with downstream effectors such as CD14 [80] and FcR to determine their full activation potential. Anti-growth factor/cytokine receptor antibodies may therefore be more effective in attenuating a hyperinflammatory storm and attendant organ damage than using individual anti-cytokine reagents for GM-CSF, IL-6 and TNF, for example [22]. Recent studies with anti CSF2R blockade by mavrilimumab show promise [12,81] and anti CSF1R blockade presents an alternative or additional option. Repurposing trials of anti-inflammatory drugs have targeted a variety of macrophage pathways, with mixed results. In each case, we have to weigh potential benefits against interfering with macrophage antimicrobial and other essential functions such as antiviral-antibody dependent killing, clearance of necrotic cells and debris, and repair, as well as the risk of potentiating inflammatory responses of mononuclear phagocytes through antibody -dependent mechanisms.","tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T374","span":{"begin":24,"end":45},"obj":"Body_part"},{"id":"T375","span":{"begin":75,"end":84},"obj":"Body_part"},{"id":"T376","span":{"begin":86,"end":98},"obj":"Body_part"},{"id":"T377","span":{"begin":103,"end":117},"obj":"Body_part"},{"id":"T378","span":{"begin":113,"end":117},"obj":"Body_part"},{"id":"T379","span":{"begin":123,"end":132},"obj":"Body_part"},{"id":"T380","span":{"begin":179,"end":187},"obj":"Body_part"},{"id":"T381","span":{"begin":288,"end":297},"obj":"Body_part"},{"id":"T382","span":{"begin":396,"end":400},"obj":"Body_part"},{"id":"T383","span":{"begin":560,"end":568},"obj":"Body_part"},{"id":"T384","span":{"begin":676,"end":681},"obj":"Body_part"},{"id":"T385","span":{"begin":716,"end":724},"obj":"Body_part"},{"id":"T386","span":{"begin":741,"end":744},"obj":"Body_part"},{"id":"T387","span":{"begin":998,"end":1008},"obj":"Body_part"},{"id":"T388","span":{"begin":1114,"end":1124},"obj":"Body_part"},{"id":"T389","span":{"begin":1187,"end":1195},"obj":"Body_part"},{"id":"T390","span":{"begin":1237,"end":1242},"obj":"Body_part"},{"id":"T391","span":{"begin":1329,"end":1351},"obj":"Body_part"},{"id":"T392","span":{"begin":1360,"end":1368},"obj":"Body_part"}],"attributes":[{"id":"A374","pred":"fma_id","subj":"T374","obj":"http://purl.org/sig/ont/fma/fma273563"},{"id":"A375","pred":"fma_id","subj":"T375","obj":"http://purl.org/sig/ont/fma/fma62864"},{"id":"A376","pred":"fma_id","subj":"T376","obj":"http://purl.org/sig/ont/fma/fma62854"},{"id":"A377","pred":"fma_id","subj":"T377","obj":"http://purl.org/sig/ont/fma/fma273565"},{"id":"A378","pred":"fma_id","subj":"T378","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A379","pred":"fma_id","subj":"T379","obj":"http://purl.org/sig/ont/fma/fma62864"},{"id":"A380","pred":"fma_id","subj":"T380","obj":"http://purl.org/sig/ont/fma/fma62864"},{"id":"A381","pred":"fma_id","subj":"T381","obj":"http://purl.org/sig/ont/fma/fma62864"},{"id":"A382","pred":"fma_id","subj":"T382","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A383","pred":"fma_id","subj":"T383","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A384","pred":"fma_id","subj":"T384","obj":"http://purl.org/sig/ont/fma/fma67498"},{"id":"A385","pred":"fma_id","subj":"T385","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A386","pred":"fma_id","subj":"T386","obj":"http://purl.org/sig/ont/fma/fma20935"},{"id":"A387","pred":"fma_id","subj":"T387","obj":"http://purl.org/sig/ont/fma/fma63261"},{"id":"A388","pred":"fma_id","subj":"T388","obj":"http://purl.org/sig/ont/fma/fma63261"},{"id":"A389","pred":"fma_id","subj":"T389","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A390","pred":"fma_id","subj":"T390","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A391","pred":"fma_id","subj":"T391","obj":"http://purl.org/sig/ont/fma/fma273563"},{"id":"A392","pred":"fma_id","subj":"T392","obj":"http://purl.org/sig/ont/fma/fma62871"},{"subj":"T374","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T375","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T376","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T377","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T378","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T379","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T380","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T381","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T382","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T383","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T384","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T385","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T386","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T387","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T388","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T389","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T390","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T391","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T392","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T88","span":{"begin":676,"end":681},"obj":"Body_part"}],"attributes":[{"id":"A88","pred":"uberon_id","subj":"T88","obj":"http://purl.obolibrary.org/obo/UBERON_0000062"},{"subj":"T88","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T197","span":{"begin":157,"end":165},"obj":"Disease"},{"id":"T198","span":{"begin":166,"end":175},"obj":"Disease"}],"attributes":[{"id":"A197","pred":"mondo_id","subj":"T197","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A198","pred":"mondo_id","subj":"T198","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"subj":"T197","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T198","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T425","span":{"begin":24,"end":45},"obj":"http://purl.obolibrary.org/obo/CL_0000113"},{"id":"T426","span":{"begin":75,"end":84},"obj":"http://purl.obolibrary.org/obo/CL_0000576"},{"id":"T427","span":{"begin":103,"end":117},"obj":"http://purl.obolibrary.org/obo/CL_0000451"},{"id":"T428","span":{"begin":123,"end":132},"obj":"http://purl.obolibrary.org/obo/CL_0000576"},{"id":"T429","span":{"begin":179,"end":187},"obj":"http://purl.obolibrary.org/obo/CL_0000576"},{"id":"T430","span":{"begin":188,"end":198},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T431","span":{"begin":288,"end":297},"obj":"http://purl.obolibrary.org/obo/CL_0000576"},{"id":"T432","span":{"begin":396,"end":400},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T433","span":{"begin":519,"end":529},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T434","span":{"begin":636,"end":637},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T435","span":{"begin":676,"end":681},"obj":"http://purl.obolibrary.org/obo/UBERON_0003103"},{"id":"T436","span":{"begin":773,"end":775},"obj":"http://purl.obolibrary.org/obo/CLO_0050507"},{"id":"T437","span":{"begin":864,"end":869},"obj":"http://purl.obolibrary.org/obo/PR_000002062"},{"id":"T438","span":{"begin":985,"end":986},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T439","span":{"begin":1237,"end":1242},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T440","span":{"begin":1329,"end":1351},"obj":"http://purl.obolibrary.org/obo/CL_0000113"}],"attributes":[{"subj":"T425","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T426","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T427","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T428","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T429","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T430","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T431","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T432","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T433","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T434","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T435","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T436","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T437","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T438","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T439","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T440","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T160","span":{"begin":725,"end":733},"obj":"Chemical"},{"id":"T161","span":{"begin":738,"end":740},"obj":"Chemical"},{"id":"T162","span":{"begin":746,"end":748},"obj":"Chemical"},{"id":"T164","span":{"begin":947,"end":970},"obj":"Chemical"},{"id":"T165","span":{"begin":965,"end":970},"obj":"Chemical"},{"id":"T166","span":{"begin":1125,"end":1138},"obj":"Chemical"},{"id":"T167","span":{"begin":1177,"end":1186},"obj":"Chemical"}],"attributes":[{"id":"A160","pred":"chebi_id","subj":"T160","obj":"http://purl.obolibrary.org/obo/CHEBI_33893"},{"id":"A161","pred":"chebi_id","subj":"T161","obj":"http://purl.obolibrary.org/obo/CHEBI_74120"},{"id":"A162","pred":"chebi_id","subj":"T162","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A163","pred":"chebi_id","subj":"T162","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A164","pred":"chebi_id","subj":"T164","obj":"http://purl.obolibrary.org/obo/CHEBI_35472"},{"id":"A165","pred":"chebi_id","subj":"T165","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A166","pred":"chebi_id","subj":"T166","obj":"http://purl.obolibrary.org/obo/CHEBI_33281"},{"id":"A167","pred":"chebi_id","subj":"T167","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"},{"subj":"T160","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T161","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T162","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T164","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T165","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T166","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T167","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T134","span":{"begin":179,"end":198},"obj":"http://purl.obolibrary.org/obo/GO_0042117"},{"id":"T135","span":{"begin":320,"end":324},"obj":"http://purl.obolibrary.org/obo/GO_0005011"},{"id":"T136","span":{"begin":396,"end":416},"obj":"http://purl.obolibrary.org/obo/GO_0030154"},{"id":"T137","span":{"begin":546,"end":552},"obj":"http://purl.obolibrary.org/obo/GO_0040007"},{"id":"T138","span":{"begin":803,"end":808},"obj":"http://purl.obolibrary.org/obo/GO_0004901"},{"id":"T139","span":{"begin":1303,"end":1325},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"attributes":[{"subj":"T134","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T135","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T136","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T137","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T138","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T139","pred":"source","obj":"LitCovid-PD-GO-BP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T181","span":{"begin":0,"end":273},"obj":"Sentence"},{"id":"T182","span":{"begin":274,"end":540},"obj":"Sentence"},{"id":"T183","span":{"begin":541,"end":777},"obj":"Sentence"},{"id":"T184","span":{"begin":778,"end":924},"obj":"Sentence"},{"id":"T185","span":{"begin":925,"end":1038},"obj":"Sentence"},{"id":"T186","span":{"begin":1039,"end":1391},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T181","pred":"source","obj":"LitCovid-sentences"},{"subj":"T182","pred":"source","obj":"LitCovid-sentences"},{"subj":"T183","pred":"source","obj":"LitCovid-sentences"},{"subj":"T184","pred":"source","obj":"LitCovid-sentences"},{"subj":"T185","pred":"source","obj":"LitCovid-sentences"},{"subj":"T186","pred":"source","obj":"LitCovid-sentences"}]},{"project":"2_test","denotations":[{"id":"32861199-29166589-26409864","span":{"begin":134,"end":136},"obj":"29166589"},{"id":"32861199-32278362-26409865","span":{"begin":773,"end":775},"obj":"32278362"}],"attributes":[{"subj":"32861199-29166589-26409864","pred":"source","obj":"2_test"},{"subj":"32861199-32278362-26409865","pred":"source","obj":"2_test"}]},{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T773","span":{"begin":24,"end":35},"obj":"GO:0005634;CL:0000113"},{"id":"T774","span":{"begin":36,"end":45},"obj":"CL:0000113"},{"id":"T775","span":{"begin":75,"end":84},"obj":"CL:0000576"},{"id":"T776","span":{"begin":86,"end":98},"obj":"CL:0000094"},{"id":"T777","span":{"begin":103,"end":112},"obj":"GO:0030425;CL:0000451"},{"id":"T778","span":{"begin":113,"end":117},"obj":"CL:0000451"},{"id":"T779","span":{"begin":123,"end":132},"obj":"CL:0000576"},{"id":"T780","span":{"begin":157,"end":165},"obj":"SP_7"},{"id":"T781","span":{"begin":179,"end":187},"obj":"CL:0000576;GO:0042117"},{"id":"T782","span":{"begin":188,"end":198},"obj":"GO:0042117"},{"id":"T783","span":{"begin":288,"end":297},"obj":"CL:0000576"},{"id":"T784","span":{"begin":320,"end":324},"obj":"PR:000005930"},{"id":"T785","span":{"begin":370,"end":384},"obj":"GO:0030097"},{"id":"T786","span":{"begin":396,"end":416},"obj":"GO:0030154"},{"id":"T787","span":{"begin":459,"end":468},"obj":"CHEBI:35224;CHEBI:35224"},{"id":"T788","span":{"begin":477,"end":481},"obj":"PR:000001889"},{"id":"T789","span":{"begin":578,"end":588},"obj":"GO:0042571"},{"id":"T790","span":{"begin":676,"end":681},"obj":"UBERON:0000062"},{"id":"T791","span":{"begin":725,"end":733},"obj":"CHEBI:33893;CHEBI:33893"},{"id":"T792","span":{"begin":738,"end":744},"obj":"PR:000005931"},{"id":"T793","span":{"begin":746,"end":750},"obj":"PR:000001393"},{"id":"T794","span":{"begin":755,"end":758},"obj":"PR:000000134"},{"id":"T795","span":{"begin":803,"end":808},"obj":"PR:000001354"},{"id":"T796","span":{"begin":864,"end":869},"obj":"PR:000002062"},{"id":"T797","span":{"begin":947,"end":970},"obj":"CHEBI:35472;CHEBI:35472"},{"id":"T798","span":{"begin":998,"end":1008},"obj":"CL:0000235"},{"id":"T799","span":{"begin":1114,"end":1124},"obj":"CL:0000235"},{"id":"T800","span":{"begin":1125,"end":1138},"obj":"CHEBI:35718;CHEBI:35718"},{"id":"T801","span":{"begin":1187,"end":1195},"obj":"GO:0042571"},{"id":"T802","span":{"begin":1259,"end":1265},"obj":"GO:0006281"},{"id":"T803","span":{"begin":1329,"end":1340},"obj":"GO:0005634;CL:0000113"},{"id":"T804","span":{"begin":1341,"end":1351},"obj":"CL:0000113"},{"id":"T805","span":{"begin":1360,"end":1368},"obj":"GO:0042571"},{"id":"T115","span":{"begin":75,"end":84},"obj":"CL:0000576"},{"id":"T116","span":{"begin":86,"end":98},"obj":"CL:0000094"},{"id":"T117","span":{"begin":103,"end":112},"obj":"GO:0030425;CL:0000451"},{"id":"T118","span":{"begin":113,"end":117},"obj":"CL:0000451"},{"id":"T26838","span":{"begin":157,"end":165},"obj":"SP_7"},{"id":"T96034","span":{"begin":19,"end":40},"obj":"GO:0030154"},{"id":"T3110","span":{"begin":84,"end":94},"obj":"CHEBI:35224;CHEBI:35224"},{"id":"T86462","span":{"begin":103,"end":107},"obj":"PR:000001889"},{"id":"T54517","span":{"begin":204,"end":214},"obj":"GO:0042571"},{"id":"T36249","span":{"begin":301,"end":306},"obj":"UBERON:0000062"},{"id":"T43026","span":{"begin":350,"end":358},"obj":"CHEBI:33893;CHEBI:33893"},{"id":"T60994","span":{"begin":363,"end":369},"obj":"PR:000005931"},{"id":"T35514","span":{"begin":371,"end":375},"obj":"PR:000001393"},{"id":"T36444","span":{"begin":380,"end":383},"obj":"PR:000000134"},{"id":"T38501","span":{"begin":428,"end":433},"obj":"PR:000001354"},{"id":"T40275","span":{"begin":488,"end":493},"obj":"PR:000002062"},{"id":"T22696","span":{"begin":571,"end":594},"obj":"CHEBI:35472;CHEBI:35472"},{"id":"T41213","span":{"begin":622,"end":633},"obj":"CL:0000235"},{"id":"T78905","span":{"begin":739,"end":749},"obj":"CL:0000235"},{"id":"T9353","span":{"begin":750,"end":763},"obj":"CHEBI:35718;CHEBI:35718"},{"id":"T16013","span":{"begin":812,"end":820},"obj":"GO:0042571"},{"id":"T76670","span":{"begin":885,"end":891},"obj":"GO:0006281"},{"id":"T69173","span":{"begin":955,"end":965},"obj":"GO:0005634;CL:0000113"},{"id":"T45620","span":{"begin":966,"end":976},"obj":"CL:0000113"},{"id":"T98084","span":{"begin":985,"end":993},"obj":"GO:0042571"},{"id":"T18148","span":{"begin":1017,"end":1027},"obj":"CL:0000235;GO:0042116"},{"id":"T60379","span":{"begin":1029,"end":1039},"obj":"GO:0042116"},{"id":"T6099","span":{"begin":1092,"end":1102},"obj":"GO:0065007"},{"id":"T32298","span":{"begin":1115,"end":1125},"obj":"GO:0010467"},{"id":"T71126","span":{"begin":1139,"end":1146},"obj":"UBERON:0000479"},{"id":"T26250","span":{"begin":1206,"end":1216},"obj":"GO:0005634;CL:0000113"},{"id":"T4462","span":{"begin":1217,"end":1227},"obj":"CL:0000113"},{"id":"T46930","span":{"begin":1241,"end":1242},"obj":"CL:0000084"},{"id":"T68613","span":{"begin":1247,"end":1259},"obj":"CL:0000236"},{"id":"T62578","span":{"begin":1297,"end":1304},"obj":"GO:0014041"},{"id":"T41272","span":{"begin":1305,"end":1307},"obj":"GO:0042116"},{"id":"T78314","span":{"begin":1308,"end":1318},"obj":"GO:0042116;CL:0000235"},{"id":"T96919","span":{"begin":1319,"end":1329},"obj":"GO:0042116"},{"id":"T14718","span":{"begin":1351,"end":1360},"obj":"CL:0000576"}],"attributes":[{"subj":"T773","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T774","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T775","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T776","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T777","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T778","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T779","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T780","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T781","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T782","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T783","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T784","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T785","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T786","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T787","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T788","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T789","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T790","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T791","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T792","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T793","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T794","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T795","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T796","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T797","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T798","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T799","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T800","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T801","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T802","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T803","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T804","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T805","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T115","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T116","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T117","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T118","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T26838","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T96034","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T3110","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T86462","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T54517","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T36249","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T43026","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T60994","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T35514","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T36444","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T38501","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T40275","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T22696","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T41213","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T78905","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T9353","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T16013","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T76670","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T69173","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T45620","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T98084","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T18148","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T60379","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T6099","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T32298","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T71126","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T26250","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T4462","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T46930","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T68613","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T62578","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T41272","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T78314","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T96919","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T14718","pred":"source","obj":"LitCovid-PMC-OGER-BB"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"705","span":{"begin":320,"end":333},"obj":"Gene"},{"id":"706","span":{"begin":477,"end":481},"obj":"Gene"},{"id":"707","span":{"begin":560,"end":577},"obj":"Gene"},{"id":"708","span":{"begin":738,"end":744},"obj":"Gene"},{"id":"709","span":{"begin":746,"end":750},"obj":"Gene"},{"id":"710","span":{"begin":755,"end":758},"obj":"Gene"},{"id":"711","span":{"begin":803,"end":808},"obj":"Gene"},{"id":"712","span":{"begin":864,"end":869},"obj":"Gene"},{"id":"713","span":{"begin":821,"end":833},"obj":"Chemical"},{"id":"714","span":{"begin":157,"end":165},"obj":"Disease"},{"id":"715","span":{"begin":166,"end":175},"obj":"Disease"},{"id":"716","span":{"begin":666,"end":688},"obj":"Disease"},{"id":"717","span":{"begin":1228,"end":1236},"obj":"Disease"}],"attributes":[{"id":"A705","pred":"tao:has_database_id","subj":"705","obj":"Gene:1435"},{"id":"A706","pred":"tao:has_database_id","subj":"706","obj":"Gene:929"},{"id":"A707","pred":"tao:has_database_id","subj":"707","obj":"Gene:8809"},{"id":"A708","pred":"tao:has_database_id","subj":"708","obj":"Gene:1437"},{"id":"A709","pred":"tao:has_database_id","subj":"709","obj":"Gene:3569"},{"id":"A710","pred":"tao:has_database_id","subj":"710","obj":"Gene:7124"},{"id":"A711","pred":"tao:has_database_id","subj":"711","obj":"Gene:1438"},{"id":"A712","pred":"tao:has_database_id","subj":"712","obj":"Gene:1436"},{"id":"A713","pred":"tao:has_database_id","subj":"713","obj":"MESH:C561644"},{"id":"A714","pred":"tao:has_database_id","subj":"714","obj":"MESH:C000657245"},{"id":"A715","pred":"tao:has_database_id","subj":"715","obj":"MESH:D007239"},{"id":"A716","pred":"tao:has_database_id","subj":"716","obj":"MESH:D019965"},{"id":"A717","pred":"tao:has_database_id","subj":"717","obj":"MESH:D009336"},{"subj":"705","pred":"source","obj":"LitCovid-PubTator"},{"subj":"706","pred":"source","obj":"LitCovid-PubTator"},{"subj":"707","pred":"source","obj":"LitCovid-PubTator"},{"subj":"708","pred":"source","obj":"LitCovid-PubTator"},{"subj":"709","pred":"source","obj":"LitCovid-PubTator"},{"subj":"710","pred":"source","obj":"LitCovid-PubTator"},{"subj":"711","pred":"source","obj":"LitCovid-PubTator"},{"subj":"712","pred":"source","obj":"LitCovid-PubTator"},{"subj":"713","pred":"source","obj":"LitCovid-PubTator"},{"subj":"714","pred":"source","obj":"LitCovid-PubTator"},{"subj":"715","pred":"source","obj":"LitCovid-PubTator"},{"subj":"716","pred":"source","obj":"LitCovid-PubTator"},{"subj":"717","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"MyTest","denotations":[{"id":"32861199-29166589-26409864","span":{"begin":134,"end":136},"obj":"29166589"},{"id":"32861199-32278362-26409865","span":{"begin":773,"end":775},"obj":"32278362"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"attributes":[{"subj":"32861199-29166589-26409864","pred":"source","obj":"MyTest"},{"subj":"32861199-32278362-26409865","pred":"source","obj":"MyTest"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#adec93","default":true},{"id":"LitCovid-PD-UBERON","color":"#ec93c7"},{"id":"LitCovid-PD-MONDO","color":"#93e1ec"},{"id":"LitCovid-PD-CLO","color":"#ecdc93"},{"id":"LitCovid-PD-CHEBI","color":"#c293ec"},{"id":"LitCovid-PD-GO-BP","color":"#93eca8"},{"id":"LitCovid-sentences","color":"#ec9397"},{"id":"2_test","color":"#93b1ec"},{"id":"LitCovid-PMC-OGER-BB","color":"#cbec93"},{"id":"LitCovid-PubTator","color":"#ec93e5"},{"id":"MyTest","color":"#93ecd9"}]}]}}