PMC:7456455 / 23885-24538 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T309","span":{"begin":0,"end":11},"obj":"Body_part"},{"id":"T310","span":{"begin":136,"end":142},"obj":"Body_part"},{"id":"T311","span":{"begin":245,"end":251},"obj":"Body_part"},{"id":"T312","span":{"begin":270,"end":281},"obj":"Body_part"},{"id":"T313","span":{"begin":307,"end":312},"obj":"Body_part"},{"id":"T314","span":{"begin":513,"end":523},"obj":"Body_part"},{"id":"T315","span":{"begin":589,"end":600},"obj":"Body_part"}],"attributes":[{"id":"A309","pred":"fma_id","subj":"T309","obj":"http://purl.org/sig/ont/fma/fma63261"},{"id":"A310","pred":"fma_id","subj":"T310","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A311","pred":"fma_id","subj":"T311","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A312","pred":"fma_id","subj":"T312","obj":"http://purl.org/sig/ont/fma/fma63261"},{"id":"A313","pred":"fma_id","subj":"T313","obj":"http://purl.org/sig/ont/fma/fma67264"},{"id":"A314","pred":"fma_id","subj":"T314","obj":"http://purl.org/sig/ont/fma/fma63261"},{"id":"A315","pred":"fma_id","subj":"T315","obj":"http://purl.org/sig/ont/fma/fma62860"}],"text":"Macrophages are central to the cellular processes which contribute to recovery from COVID-19 infection; they remove debris and necrotic tissue through phagocytosis and secretion of elastase and collagenase, and produce IGF1 and TGF-β to promote tissue recovery. M2-like macrophages are the source of potent lipid metabolites which resolve inflammation; these include resolvins, protectins and maresins, short lived autacoids which regulate the magnitude and duration of acute inflammation [25,73]. Acting through macrophage GPCRs for these metabolites, they enhance efferocytosis of dying neutrophils, and counter inflammation without immunosuppression."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T77","span":{"begin":136,"end":142},"obj":"Body_part"},{"id":"T78","span":{"begin":245,"end":251},"obj":"Body_part"}],"attributes":[{"id":"A77","pred":"uberon_id","subj":"T77","obj":"http://purl.obolibrary.org/obo/UBERON_0000479"},{"id":"A78","pred":"uberon_id","subj":"T78","obj":"http://purl.obolibrary.org/obo/UBERON_0000479"}],"text":"Macrophages are central to the cellular processes which contribute to recovery from COVID-19 infection; they remove debris and necrotic tissue through phagocytosis and secretion of elastase and collagenase, and produce IGF1 and TGF-β to promote tissue recovery. M2-like macrophages are the source of potent lipid metabolites which resolve inflammation; these include resolvins, protectins and maresins, short lived autacoids which regulate the magnitude and duration of acute inflammation [25,73]. Acting through macrophage GPCRs for these metabolites, they enhance efferocytosis of dying neutrophils, and counter inflammation without immunosuppression."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T160","span":{"begin":84,"end":92},"obj":"Disease"},{"id":"T161","span":{"begin":93,"end":102},"obj":"Disease"},{"id":"T162","span":{"begin":339,"end":351},"obj":"Disease"},{"id":"T163","span":{"begin":476,"end":488},"obj":"Disease"},{"id":"T164","span":{"begin":614,"end":626},"obj":"Disease"}],"attributes":[{"id":"A160","pred":"mondo_id","subj":"T160","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A161","pred":"mondo_id","subj":"T161","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A162","pred":"mondo_id","subj":"T162","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A163","pred":"mondo_id","subj":"T163","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A164","pred":"mondo_id","subj":"T164","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"}],"text":"Macrophages are central to the cellular processes which contribute to recovery from COVID-19 infection; they remove debris and necrotic tissue through phagocytosis and secretion of elastase and collagenase, and produce IGF1 and TGF-β to promote tissue recovery. M2-like macrophages are the source of potent lipid metabolites which resolve inflammation; these include resolvins, protectins and maresins, short lived autacoids which regulate the magnitude and duration of acute inflammation [25,73]. Acting through macrophage GPCRs for these metabolites, they enhance efferocytosis of dying neutrophils, and counter inflammation without immunosuppression."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T111","span":{"begin":262,"end":264},"obj":"Chemical"},{"id":"T113","span":{"begin":307,"end":312},"obj":"Chemical"},{"id":"T114","span":{"begin":313,"end":324},"obj":"Chemical"},{"id":"T115","span":{"begin":367,"end":376},"obj":"Chemical"},{"id":"T116","span":{"begin":540,"end":551},"obj":"Chemical"}],"attributes":[{"id":"A111","pred":"chebi_id","subj":"T111","obj":"http://purl.obolibrary.org/obo/CHEBI_34827"},{"id":"A112","pred":"chebi_id","subj":"T111","obj":"http://purl.obolibrary.org/obo/CHEBI_51112"},{"id":"A113","pred":"chebi_id","subj":"T113","obj":"http://purl.obolibrary.org/obo/CHEBI_18059"},{"id":"A114","pred":"chebi_id","subj":"T114","obj":"http://purl.obolibrary.org/obo/CHEBI_25212"},{"id":"A115","pred":"chebi_id","subj":"T115","obj":"http://purl.obolibrary.org/obo/CHEBI_132120"},{"id":"A116","pred":"chebi_id","subj":"T116","obj":"http://purl.obolibrary.org/obo/CHEBI_25212"}],"text":"Macrophages are central to the cellular processes which contribute to recovery from COVID-19 infection; they remove debris and necrotic tissue through phagocytosis and secretion of elastase and collagenase, and produce IGF1 and TGF-β to promote tissue recovery. M2-like macrophages are the source of potent lipid metabolites which resolve inflammation; these include resolvins, protectins and maresins, short lived autacoids which regulate the magnitude and duration of acute inflammation [25,73]. Acting through macrophage GPCRs for these metabolites, they enhance efferocytosis of dying neutrophils, and counter inflammation without immunosuppression."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T109","span":{"begin":31,"end":49},"obj":"http://purl.obolibrary.org/obo/GO_0009987"},{"id":"T110","span":{"begin":151,"end":163},"obj":"http://purl.obolibrary.org/obo/GO_0006909"},{"id":"T111","span":{"begin":168,"end":177},"obj":"http://purl.obolibrary.org/obo/GO_0046903"},{"id":"T112","span":{"begin":339,"end":351},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T113","span":{"begin":476,"end":488},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T114","span":{"begin":566,"end":579},"obj":"http://purl.obolibrary.org/obo/GO_0043277"},{"id":"T115","span":{"begin":614,"end":626},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"text":"Macrophages are central to the cellular processes which contribute to recovery from COVID-19 infection; they remove debris and necrotic tissue through phagocytosis and secretion of elastase and collagenase, and produce IGF1 and TGF-β to promote tissue recovery. M2-like macrophages are the source of potent lipid metabolites which resolve inflammation; these include resolvins, protectins and maresins, short lived autacoids which regulate the magnitude and duration of acute inflammation [25,73]. Acting through macrophage GPCRs for these metabolites, they enhance efferocytosis of dying neutrophils, and counter inflammation without immunosuppression."}

{"project":"LitCovid-sentences","denotations":[{"id":"T142","span":{"begin":0,"end":261},"obj":"Sentence"},{"id":"T143","span":{"begin":262,"end":497},"obj":"Sentence"},{"id":"T144","span":{"begin":498,"end":653},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Macrophages are central to the cellular processes which contribute to recovery from COVID-19 infection; they remove debris and necrotic tissue through phagocytosis and secretion of elastase and collagenase, and produce IGF1 and TGF-β to promote tissue recovery. M2-like macrophages are the source of potent lipid metabolites which resolve inflammation; these include resolvins, protectins and maresins, short lived autacoids which regulate the magnitude and duration of acute inflammation [25,73]. Acting through macrophage GPCRs for these metabolites, they enhance efferocytosis of dying neutrophils, and counter inflammation without immunosuppression."}

{"project":"2_test","denotations":[{"id":"32861199-29302056-26409855","span":{"begin":493,"end":495},"obj":"29302056"}],"text":"Macrophages are central to the cellular processes which contribute to recovery from COVID-19 infection; they remove debris and necrotic tissue through phagocytosis and secretion of elastase and collagenase, and produce IGF1 and TGF-β to promote tissue recovery. M2-like macrophages are the source of potent lipid metabolites which resolve inflammation; these include resolvins, protectins and maresins, short lived autacoids which regulate the magnitude and duration of acute inflammation [25,73]. Acting through macrophage GPCRs for these metabolites, they enhance efferocytosis of dying neutrophils, and counter inflammation without immunosuppression."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T636","span":{"begin":0,"end":11},"obj":"CL:0000235"},{"id":"T637","span":{"begin":31,"end":49},"obj":"GO:0009987"},{"id":"T638","span":{"begin":84,"end":92},"obj":"SP_7"},{"id":"T639","span":{"begin":136,"end":142},"obj":"UBERON:0000479"},{"id":"T640","span":{"begin":151,"end":163},"obj":"GO:0006909"},{"id":"T641","span":{"begin":219,"end":223},"obj":"PR:P08025"},{"id":"T642","span":{"begin":228,"end":233},"obj":"PR:000000046"},{"id":"T643","span":{"begin":245,"end":251},"obj":"UBERON:0000479"},{"id":"T644","span":{"begin":270,"end":281},"obj":"CL:0000235"},{"id":"T645","span":{"begin":307,"end":312},"obj":"CHEBI:18059;CHEBI:18059"},{"id":"T646","span":{"begin":313,"end":324},"obj":"CHEBI:25212;CHEBI:25212"},{"id":"T647","span":{"begin":431,"end":439},"obj":"GO:0065007"},{"id":"T648","span":{"begin":513,"end":523},"obj":"CL:0000235"},{"id":"T649","span":{"begin":540,"end":551},"obj":"CHEBI:25212;CHEBI:25212"},{"id":"T650","span":{"begin":566,"end":579},"obj":"GO:0043277"},{"id":"T651","span":{"begin":580,"end":582},"obj":"GO:0072672"},{"id":"T652","span":{"begin":583,"end":588},"obj":"GO:0016265"},{"id":"T653","span":{"begin":589,"end":600},"obj":"CL:0000775"},{"id":"T36268","span":{"begin":54,"end":62},"obj":"GO:0065007"},{"id":"T47670","span":{"begin":136,"end":146},"obj":"CL:0000235"},{"id":"T58391","span":{"begin":163,"end":172},"obj":"CHEBI:25212;CHEBI:25212"},{"id":"T94413","span":{"begin":187,"end":200},"obj":"GO:0043277"},{"id":"T65804","span":{"begin":201,"end":203},"obj":"GO:0072672"},{"id":"T18008","span":{"begin":204,"end":209},"obj":"GO:0016265"},{"id":"T89699","span":{"begin":210,"end":219},"obj":"CL:0000775"},{"id":"T76411","span":{"begin":373,"end":378},"obj":"UBERON:0000062"},{"id":"T19819","span":{"begin":515,"end":524},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T60054","span":{"begin":577,"end":587},"obj":"CL:0000080"},{"id":"T29136","span":{"begin":588,"end":593},"obj":"CL:0000842;UBERON:0000178"},{"id":"T8541","span":{"begin":594,"end":606},"obj":"GO:0005634;CL:0000842"},{"id":"T74739","span":{"begin":607,"end":612},"obj":"CL:0000842"},{"id":"T8528","span":{"begin":639,"end":647},"obj":"SP_7"}],"text":"Macrophages are central to the cellular processes which contribute to recovery from COVID-19 infection; they remove debris and necrotic tissue through phagocytosis and secretion of elastase and collagenase, and produce IGF1 and TGF-β to promote tissue recovery. M2-like macrophages are the source of potent lipid metabolites which resolve inflammation; these include resolvins, protectins and maresins, short lived autacoids which regulate the magnitude and duration of acute inflammation [25,73]. Acting through macrophage GPCRs for these metabolites, they enhance efferocytosis of dying neutrophils, and counter inflammation without immunosuppression."}

{"project":"LitCovid-PubTator","denotations":[{"id":"573","span":{"begin":219,"end":223},"obj":"Gene"},{"id":"574","span":{"begin":228,"end":233},"obj":"Gene"},{"id":"575","span":{"begin":307,"end":312},"obj":"Chemical"},{"id":"576","span":{"begin":84,"end":92},"obj":"Disease"},{"id":"577","span":{"begin":93,"end":102},"obj":"Disease"},{"id":"578","span":{"begin":127,"end":135},"obj":"Disease"},{"id":"579","span":{"begin":339,"end":351},"obj":"Disease"},{"id":"580","span":{"begin":476,"end":488},"obj":"Disease"},{"id":"581","span":{"begin":614,"end":626},"obj":"Disease"}],"attributes":[{"id":"A573","pred":"tao:has_database_id","subj":"573","obj":"Gene:3479"},{"id":"A574","pred":"tao:has_database_id","subj":"574","obj":"Gene:7039"},{"id":"A575","pred":"tao:has_database_id","subj":"575","obj":"MESH:D008055"},{"id":"A576","pred":"tao:has_database_id","subj":"576","obj":"MESH:C000657245"},{"id":"A577","pred":"tao:has_database_id","subj":"577","obj":"MESH:D007239"},{"id":"A578","pred":"tao:has_database_id","subj":"578","obj":"MESH:D009336"},{"id":"A579","pred":"tao:has_database_id","subj":"579","obj":"MESH:D007249"},{"id":"A580","pred":"tao:has_database_id","subj":"580","obj":"MESH:D007249"},{"id":"A581","pred":"tao:has_database_id","subj":"581","obj":"MESH:D007249"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Macrophages are central to the cellular processes which contribute to recovery from COVID-19 infection; they remove debris and necrotic tissue through phagocytosis and secretion of elastase and collagenase, and produce IGF1 and TGF-β to promote tissue recovery. M2-like macrophages are the source of potent lipid metabolites which resolve inflammation; these include resolvins, protectins and maresins, short lived autacoids which regulate the magnitude and duration of acute inflammation [25,73]. Acting through macrophage GPCRs for these metabolites, they enhance efferocytosis of dying neutrophils, and counter inflammation without immunosuppression."}

{"project":"MyTest","denotations":[{"id":"32861199-29302056-26409855","span":{"begin":493,"end":495},"obj":"29302056"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"Macrophages are central to the cellular processes which contribute to recovery from COVID-19 infection; they remove debris and necrotic tissue through phagocytosis and secretion of elastase and collagenase, and produce IGF1 and TGF-β to promote tissue recovery. M2-like macrophages are the source of potent lipid metabolites which resolve inflammation; these include resolvins, protectins and maresins, short lived autacoids which regulate the magnitude and duration of acute inflammation [25,73]. Acting through macrophage GPCRs for these metabolites, they enhance efferocytosis of dying neutrophils, and counter inflammation without immunosuppression."}