PMC:7456455 / 17306-18556
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T222 | 219-224 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
| T223 | 225-234 | Body_part | denotes | monocytes | http://purl.org/sig/ont/fma/fma62864 |
| T224 | 267-271 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T225 | 439-443 | Body_part | denotes | toes | http://purl.org/sig/ont/fma/fma70664 |
| T226 | 448-455 | Body_part | denotes | fingers | http://purl.org/sig/ont/fma/fma9666 |
| T227 | 620-628 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
| T228 | 660-665 | Body_part | denotes | heart | http://purl.org/sig/ont/fma/fma7088 |
| T229 | 678-682 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T230 | 731-739 | Body_part | denotes | platelet | http://purl.org/sig/ont/fma/fma62851 |
| T231 | 752-774 | Body_part | denotes | mononuclear phagocytes | http://purl.org/sig/ont/fma/fma273563 |
| T232 | 796-802 | Body_part | denotes | tissue | http://purl.org/sig/ont/fma/fma9637 |
| T233 | 883-894 | Body_part | denotes | endothelium | http://purl.org/sig/ont/fma/fma63916 |
| T234 | 912-923 | Body_part | denotes | macrophages | http://purl.org/sig/ont/fma/fma63261 |
| T235 | 1049-1055 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T56 | 219-224 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T57 | 267-271 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T58 | 448-455 | Body_part | denotes | fingers | http://purl.obolibrary.org/obo/UBERON_0002389 |
| T59 | 660-665 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/UBERON_0000948 |
| T60 | 678-682 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T61 | 796-802 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
| T62 | 883-894 | Body_part | denotes | endothelium | http://purl.obolibrary.org/obo/UBERON_0001986 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T120 | 92-107 | Disease | denotes | viral infection | http://purl.obolibrary.org/obo/MONDO_0005108 |
| T121 | 98-107 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T122 | 364-373 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T123 | 423-435 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T124 | 577-585 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T125 | 630-649 | Disease | denotes | systemic vasculitis | http://purl.obolibrary.org/obo/MONDO_0018882 |
| T126 | 1166-1176 | Disease | denotes | thrombosis | http://purl.obolibrary.org/obo/MONDO_0000831 |
| T127 | 1187-1202 | Disease | denotes | viral infection | http://purl.obolibrary.org/obo/MONDO_0005108 |
| T128 | 1193-1202 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T129 | 1240-1249 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T247 | 219-224 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T248 | 219-224 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T249 | 225-234 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | monocytes |
| T250 | 267-271 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T251 | 267-271 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T252 | 345-346 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T253 | 660-665 | http://purl.obolibrary.org/obo/UBERON_0000948 | denotes | heart |
| T254 | 660-665 | http://purl.obolibrary.org/obo/UBERON_0007100 | denotes | heart |
| T255 | 660-665 | http://purl.obolibrary.org/obo/UBERON_0015228 | denotes | heart |
| T256 | 660-665 | http://www.ebi.ac.uk/efo/EFO_0000815 | denotes | heart |
| T257 | 678-682 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T258 | 678-682 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T259 | 740-750 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
| T260 | 752-774 | http://purl.obolibrary.org/obo/CL_0000113 | denotes | mononuclear phagocytes |
| T261 | 883-894 | http://purl.obolibrary.org/obo/UBERON_0001986 | denotes | endothelium |
| T262 | 982-993 | http://purl.obolibrary.org/obo/PR_000012867 | denotes | plasminogen |
| T263 | 1010-1018 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T264 | 1049-1055 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T265 | 1065-1085 | http://purl.obolibrary.org/obo/PR_000024845 | denotes | alpha2 macroglobulin |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T76 | 703-718 | Chemical | denotes | corticosteroids | http://purl.obolibrary.org/obo/CHEBI_50858 |
| T77 | 1035-1045 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T78 | 1152-1162 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T63 | 92-107 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infection |
| T64 | 423-435 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
| T65 | 557-573 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune responses |
| T66 | 731-750 | http://purl.obolibrary.org/obo/GO_0030168 | denotes | platelet activation |
| T67 | 858-870 | http://purl.obolibrary.org/obo/GO_0042730 | denotes | fibrinolysis |
| T68 | 944-953 | http://purl.obolibrary.org/obo/GO_0046903 | denotes | secretion |
| T69 | 1065-1085 | http://purl.obolibrary.org/obo/GO_0004866 | denotes | alpha2 macroglobulin |
| T70 | 1187-1202 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infection |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T103 | 0-240 | Sentence | denotes | We have little understanding of the innate and adaptive mechanisms that fail to clear local viral infection and at what stage IFN [55,56], other pro-inflammatory [57] and haematopoietic responses become dysregulated in blood monocytes [58]. |
| T104 | 241-344 | Sentence | denotes | Together with compromised lung oxygenation, this can lead to systemic immune and vascular dysfunctions. |
| T105 | 345-461 | Sentence | denotes | A syndrome of mild infection in younger subjects gives rise to chilblain-like inflammation in toes and fingers [59]. |
| T106 | 462-594 | Sentence | denotes | The uncommon multisystem Kawasaki-like inflammatory syndrome of children results from atypical immune responses to COVID-19 [60,61]. |
| T107 | 595-719 | Sentence | denotes | This involves anti-viral antibody, systemic vasculitis affecting heart rather than lung, and can respond to corticosteroids. |
| T108 | 720-1086 | Sentence | denotes | Apart from platelet activation, mononuclear phagocytes are known to produce tissue factor and other procoagulants [62], Factors 5 and 13; fibrinolysis by vascular endothelium and inflammatory macrophages [63] is mediated by secretion of urokinase, which cleaves plasminogen to plasmin; its activity is regulated by inhibitors in plasma, such as alpha2 macroglobulin. |
| T109 | 1087-1250 | Sentence | denotes | Anticoagulants and intranasal or inhaled Type1 IFN may be useful inhibitors of thrombosis and local viral infection, limiting progression to more severe infection. |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T24 | 408-417 | Phenotype | denotes | chilblain | http://purl.obolibrary.org/obo/HP_0009710 |
| T25 | 639-649 | Phenotype | denotes | vasculitis | http://purl.obolibrary.org/obo/HP_0002633 |
| T26 | 1233-1249 | Phenotype | denotes | severe infection | http://purl.obolibrary.org/obo/HP_0032169 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32861199-32651212-26409842 | 131-133 | 32651212 | denotes | 55 |
| 32861199-32386460-26409843 | 457-459 | 32386460 | denotes | 59 |
| 32861199-31048328-26409844 | 835-837 | 31048328 | denotes | 62 |
| 32861199-4427092-26409845 | 925-927 | 4427092 | denotes | 63 |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T458 | 92-97 | NCBITaxon:10239 | denotes | viral |
| T459 | 171-185 | GO:0030097 | denotes | haematopoietic |
| T460 | 203-215 | GO:0065007 | denotes | dysregulated |
| T461 | 219-224 | CL:0000081;UBERON:0000178 | denotes | blood |
| T462 | 225-234 | CL:0000576 | denotes | monocytes |
| T463 | 267-271 | UBERON:0002048 | denotes | lung |
| T464 | 272-283 | GO:0015671 | denotes | oxygenation |
| T465 | 311-317 | UBERON:0002405 | denotes | immune |
| T466 | 439-443 | UBERON:0002544 | denotes | toes |
| T467 | 448-455 | UBERON:0002544 | denotes | fingers |
| T468 | 475-486 | UBERON:0000467 | denotes | multisystem |
| T469 | 557-563 | UBERON:0002405;GO:0006955 | denotes | immune |
| T470 | 564-573 | GO:0006955 | denotes | responses |
| T471 | 577-585 | SP_7 | denotes | COVID-19 |
| T472 | 614-619 | NCBITaxon:10239 | denotes | viral |
| T473 | 620-628 | GO:0042571 | denotes | antibody |
| T474 | 660-665 | UBERON:0000948 | denotes | heart |
| T475 | 678-682 | UBERON:0002048 | denotes | lung |
| T476 | 703-718 | CHEBI:50858;CHEBI:50858 | denotes | corticosteroids |
| T477 | 731-739 | CL:0000233;GO:0030168 | denotes | platelet |
| T478 | 740-750 | GO:0030168 | denotes | activation |
| T479 | 752-763 | GO:0005634;CL:0000113 | denotes | mononuclear |
| T480 | 764-774 | CL:0000113 | denotes | phagocytes |
| T481 | 796-802 | UBERON:0000479;PR:000001940 | denotes | tissue |
| T482 | 803-809 | PR:000001940 | denotes | factor |
| T483 | 858-870 | GO:0042730 | denotes | fibrinolysis |
| T484 | 883-894 | UBERON:0001986 | denotes | endothelium |
| T485 | 899-923 | CL:0000863 | denotes | inflammatory macrophages |
| T486 | 974-981 | MOP:0000780 | denotes | cleaves |
| T487 | 1022-1031 | GO:0065007 | denotes | regulated |
| T488 | 1035-1045 | CHEBI:35222;CHEBI:35222 | denotes | inhibitors |
| T489 | 1049-1055 | UBERON:0001969 | denotes | plasma |
| T490 | 1065-1071 | PR:000024845 | denotes | alpha2 |
| T491 | 1072-1085 | GO:0019814 | denotes | macroglobulin |
| T492 | 1087-1101 | CHEBI:50249;CHEBI:50249 | denotes | Anticoagulants |
| T493 | 1152-1162 | CHEBI:35222;CHEBI:35222 | denotes | inhibitors |
| T494 | 1166-1176 | GO:0007596 | denotes | thrombosis |
| T495 | 1187-1192 | NCBITaxon:10239 | denotes | viral |
| T58734 | 62-66 | UBERON:0002544 | denotes | isms |
| T32061 | 71-78 | UBERON:0002544 | denotes | fail t |
| T33619 | 98-108 | UBERON:0000467 | denotes | infection |
| T12340 | 176-181 | UBERON:0002405;GO:0006955 | denotes | topoi |
| T66700 | 182-191 | GO:0006955 | denotes | tic respo |
| T67364 | 195-203 | SP_7 | denotes | become |
| T15302 | 232-237 | NCBITaxon:10239 | denotes | es [5 |
| T75633 | 238-246 | GO:0042571 | denotes | ]. Toget |
| T6459 | 278-283 | UBERON:0000948 | denotes | ation |
| T6860 | 296-300 | UBERON:0002048 | denotes | ad t |
| T98456 | 322-337 | CHEBI:50858;CHEBI:50858 | denotes | vascular dysfun |
| T14966 | 350-358 | CL:0000233;GO:0030168 | denotes | drome of |
| T45600 | 359-369 | GO:0030168 | denotes | mild infec |
| T79987 | 371-381 | GO:0005634;CL:0000113 | denotes | on in youn |
| T1954 | 382-392 | CL:0000113 | denotes | er subject |
| T21081 | 416-422 | UBERON:0000479;PR:000001940 | denotes | n-like |
| T97661 | 423-429 | PR:000001940 | denotes | inflam |
| T63857 | 479-491 | GO:0042730 | denotes | isystem Kawa |
| T77132 | 504-515 | UBERON:0001986 | denotes | lammatory s |
| T77185 | 520-546 | CL:0000863 | denotes | me of children results fro |
| T8187 | 599-606 | MOP:0000780 | denotes | involv |
| T9373 | 647-656 | GO:0065007 | denotes | is affect |
| T21640 | 660-670 | CHEBI:35222;CHEBI:35222 | denotes | heart rath |
| T99870 | 674-680 | UBERON:0001969 | denotes | han lu |
| T19554 | 690-692 | PR:000024845 | denotes | n |
| T95758 | 693-706 | GO:0019814 | denotes | espond to cor |
| T23878 | 708-722 | CHEBI:50249;CHEBI:50249 | denotes | costeroids. Ap |
| T10343 | 774-784 | CHEBI:35222;CHEBI:35222 | denotes | are known |
| T99705 | 788-798 | GO:0007596 | denotes | produce ti |
| T50075 | 809-814 | NCBITaxon:10239 | denotes | and |
| T61546 | 963-971 | SP_7 | denotes | ase, whi |
| T34293 | 1015-1019 | UBERON:0002048 | denotes | ity |
| T21856 | 1185-1190 | NCBITaxon:10239 | denotes | l vir |
| T60934 | 1204-1208 | G_3;PG_10;PR:000003622 | denotes | limi |
| T68737 | 1209-1217 | UBERON:0000483 | denotes | ing prog |
| T62751 | 1222-1232 | UBERON:0001986;CL:0000115 | denotes | on to more |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 411 | 1065-1085 | Gene | denotes | alpha2 macroglobulin | Gene:2 |
| 412 | 526-534 | Species | denotes | children | Tax:9606 |
| 413 | 92-107 | Disease | denotes | viral infection | MESH:D001102 |
| 414 | 322-343 | Disease | denotes | vascular dysfunctions | MESH:D002561 |
| 415 | 345-355 | Disease | denotes | A syndrome | MESH:D061325 |
| 416 | 364-373 | Disease | denotes | infection | MESH:D007239 |
| 417 | 423-435 | Disease | denotes | inflammation | MESH:D007249 |
| 418 | 439-443 | Disease | denotes | toes | MESH:D000070592 |
| 419 | 577-585 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 420 | 630-649 | Disease | denotes | systemic vasculitis | MESH:D056647 |
| 421 | 1166-1176 | Disease | denotes | thrombosis | MESH:D013927 |
| 422 | 1187-1202 | Disease | denotes | viral infection | MESH:D001102 |
| 423 | 1240-1249 | Disease | denotes | infection | MESH:D007239 |
MyTest
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32861199-32651212-26409842 | 131-133 | 32651212 | denotes | 55 |
| 32861199-32386460-26409843 | 457-459 | 32386460 | denotes | 59 |
| 32861199-31048328-26409844 | 835-837 | 31048328 | denotes | 62 |
| 32861199-4427092-26409845 | 925-927 | 4427092 | denotes | 63 |