PMC:7456455 / 11806-12841
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T143 | 42-53 | Body_part | denotes | macrophages | http://purl.org/sig/ont/fma/fma63261 |
| T144 | 359-370 | Body_part | denotes | macrophages | http://purl.org/sig/ont/fma/fma63261 |
| T145 | 529-551 | Body_part | denotes | Mononuclear phagocytes | http://purl.org/sig/ont/fma/fma273563 |
| T146 | 709-714 | Body_part | denotes | organ | http://purl.org/sig/ont/fma/fma67498 |
| T147 | 749-760 | Body_part | denotes | macrophages | http://purl.org/sig/ont/fma/fma63261 |
| T148 | 798-803 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T149 | 905-914 | Body_part | denotes | Microglia | http://purl.org/sig/ont/fma/fma68923 |
| T150 | 972-979 | Body_part | denotes | neurons | http://purl.org/sig/ont/fma/fma54527 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T33 | 709-714 | Body_part | denotes | organ | http://purl.obolibrary.org/obo/UBERON_0000062 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T76 | 8-21 | Disease | denotes | infections in | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T77 | 73-85 | Disease | denotes | tuberculosis | http://purl.obolibrary.org/obo/MONDO_0018076 |
| T78 | 90-94 | Disease | denotes | AIDS | http://purl.obolibrary.org/obo/MONDO_0012268 |
| T79 | 123-132 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T80 | 195-201 | Disease | denotes | asthma | http://purl.obolibrary.org/obo/MONDO_0004979 |
| T81 | 218-226 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T82 | 486-490 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T83 | 613-629 | Disease | denotes | immunodeficiency | http://purl.obolibrary.org/obo/MONDO_0021094 |
| T84 | 677-698 | Disease | denotes | chronic renal disease | http://purl.obolibrary.org/obo/MONDO_0005300 |
| T85 | 685-698 | Disease | denotes | renal disease | http://purl.obolibrary.org/obo/MONDO_0002118|http://purl.obolibrary.org/obo/MONDO_0005240 |
| T87 | 732-737 | Disease | denotes | Tumor | http://purl.obolibrary.org/obo/MONDO_0005070 |
| T88 | 762-765 | Disease | denotes | TAM | http://purl.obolibrary.org/obo/MONDO_0008040 |
| T89 | 890-898 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T90 | 983-1000 | Disease | denotes | Alzheimer disease | http://purl.obolibrary.org/obo/MONDO_0004975 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T178 | 32-41 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activated |
| T179 | 59-60 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T180 | 497-499 | http://purl.obolibrary.org/obo/CLO_0053799 | denotes | 45 |
| T181 | 529-551 | http://purl.obolibrary.org/obo/CL_0000113 | denotes | Mononuclear phagocytes |
| T182 | 709-714 | http://purl.obolibrary.org/obo/UBERON_0003103 | denotes | organ |
| T183 | 798-803 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T184 | 905-914 | http://purl.obolibrary.org/obo/CL_0000129 | denotes | Microglia |
| T185 | 1002-1003 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T50 | 304-306 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T52 | 356-358 | Chemical | denotes | M2 | http://purl.obolibrary.org/obo/CHEBI_34827|http://purl.obolibrary.org/obo/CHEBI_51112 |
| T54 | 407-410 | Chemical | denotes | BCG | http://purl.obolibrary.org/obo/CHEBI_41001 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T71 | 0-180 | Sentence | denotes | Chronic infections in which TH1-activated macrophages play a major role, tuberculosis and AIDS, enhance the risk of severe infection, with odds ratios of 1.7 and 2.3– respectively. |
| T72 | 181-303 | Sentence | denotes | TH2-dependent asthma may not enhance COVID-19 susceptibility, possibly correlated with low levels of ACE2 expression [44]. |
| T73 | 304-406 | Sentence | denotes | IL-13 also reduces ACE2 expression, suggesting that M2-macrophages may contribute to viral resistance. |
| T74 | 407-528 | Sentence | denotes | BCG and other immunisations may transiently promote non-specific resistance to SARS-CoV2 [45], to be confirmed in trials. |
| T75 | 529-731 | Sentence | denotes | Mononuclear phagocytes are implicated in selected genetic [46] or acquired systemic immunodeficiency, immunosuppression and autoimmunity, including chronic renal disease requiring organ transplantation. |
| T76 | 732-904 | Sentence | denotes | Tumor associated macrophages (TAM) and Myeloid derived suppressor cells (MDSC) promote malignancy and metastasis, and with chemo-and radiotherapy may enhance COVID-19 risk. |
| T77 | 905-1035 | Sentence | denotes | Microglia contribute to neurodegeneration through interaction with neurons in Alzheimer disease, a comorbidity independent of age. |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T7 | 0-21 | Phenotype | denotes | Chronic infections in | http://purl.obolibrary.org/obo/HP_0031035 |
| T8 | 116-132 | Phenotype | denotes | severe infection | http://purl.obolibrary.org/obo/HP_0032169 |
| T9 | 195-201 | Phenotype | denotes | asthma | http://purl.obolibrary.org/obo/HP_0002099 |
| T10 | 613-629 | Phenotype | denotes | immunodeficiency | http://purl.obolibrary.org/obo/HP_0002721 |
| T11 | 653-665 | Phenotype | denotes | autoimmunity | http://purl.obolibrary.org/obo/HP_0002960 |
| T12 | 732-737 | Phenotype | denotes | Tumor | http://purl.obolibrary.org/obo/HP_0002664 |
| T13 | 929-946 | Phenotype | denotes | neurodegeneration | http://purl.obolibrary.org/obo/HP_0002180 |
| T14 | 983-1000 | Phenotype | denotes | Alzheimer disease | http://purl.obolibrary.org/obo/HP_0002511 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32861199-31953710-26409835 | 588-590 | 31953710 | denotes | 46 |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T319 | 28-31 | PR:000008439 | denotes | TH1 |
| T320 | 32-41 | CL:0002627 | denotes | activated |
| T321 | 42-53 | CL:0000235 | denotes | macrophages |
| T322 | 218-226 | SP_7 | denotes | COVID-19 |
| T323 | 282-286 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
| T324 | 287-297 | GO:0010467 | denotes | expression |
| T325 | 304-309 | PR:000001370 | denotes | IL-13 |
| T326 | 323-327 | PR:000003622;G_3;PG_10 | denotes | ACE2 |
| T327 | 328-338 | GO:0010467 | denotes | expression |
| T328 | 359-370 | CL:0000235 | denotes | macrophages |
| T329 | 389-394 | NCBITaxon:10239 | denotes | viral |
| T330 | 486-495 | SP_7 | denotes | SARS-CoV2 |
| T331 | 529-540 | GO:0005634;CL:0000113 | denotes | Mononuclear |
| T332 | 541-551 | CL:0000113 | denotes | phagocytes |
| T333 | 579-586 | SO:0000704 | denotes | genetic |
| T334 | 685-690 | UBERON:0002113 | denotes | renal |
| T335 | 709-714 | UBERON:0000062 | denotes | organ |
| T336 | 749-760 | CL:0000235 | denotes | macrophages |
| T337 | 762-765 | PR:000024024 | denotes | TAM |
| T338 | 771-778 | CL:0000763 | denotes | Myeloid |
| T339 | 890-898 | SP_7 | denotes | COVID-19 |
| T340 | 905-914 | CL:0000129 | denotes | Microglia |
| T341 | 972-979 | CL:0000540 | denotes | neurons |
| T16231 | 15-20 | NCBITaxon:10239 | denotes | ons i |
| T72387 | 111-120 | SP_7 | denotes | k of seve |
| T85782 | 154-164 | GO:0005634;CL:0000113 | denotes | 1.7 and 2. |
| T6098 | 165-175 | CL:0000113 | denotes | – respecti |
| T38151 | 203-210 | SO:0000704 | denotes | ay not |
| T25165 | 306-311 | UBERON:0002113 | denotes | -13 a |
| T89913 | 330-335 | UBERON:0000062 | denotes | press |
| T90361 | 370-381 | CL:0000235 | denotes | may contri |
| T65284 | 383-386 | PR:000024024 | denotes | te |
| T23224 | 392-399 | CL:0000763 | denotes | al resi |
| T73660 | 510-518 | SP_7 | denotes | nfirmed |
| T98851 | 525-535 | CL:0000129 | denotes | ls. Mononu |
| T66029 | 593-600 | CL:0000540 | denotes | r acqui |
| T54215 | 737-747 | CL:0000235 | denotes | associate |
| T52904 | 771-775 | G_3;PG_10;PR:000003622 | denotes | Myel |
| T82666 | 789-801 | GO:0000805 | denotes | ppressor cel |
| T89737 | 867-874 | SO:0000704 | denotes | diother |
| T36121 | 1016-1026 | CL:0000235 | denotes | independen |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 259 | 28-31 | Gene | denotes | TH1 | Gene:51497 |
| 260 | 282-286 | Gene | denotes | ACE2 | Gene:59272 |
| 261 | 304-309 | Gene | denotes | IL-13 | Gene:3596 |
| 262 | 323-327 | Gene | denotes | ACE2 | Gene:59272 |
| 263 | 486-495 | Species | denotes | SARS-CoV2 | Tax:2697049 |
| 264 | 181-184 | Chemical | denotes | TH2 | |
| 265 | 0-18 | Disease | denotes | Chronic infections | MESH:D007239 |
| 266 | 73-85 | Disease | denotes | tuberculosis | MESH:D014376 |
| 267 | 90-94 | Disease | denotes | AIDS | MESH:D000163 |
| 268 | 123-132 | Disease | denotes | infection | MESH:D007239 |
| 269 | 195-201 | Disease | denotes | asthma | MESH:D001249 |
| 270 | 218-226 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 271 | 604-629 | Disease | denotes | systemic immunodeficiency | MESH:D007154 |
| 272 | 653-665 | Disease | denotes | autoimmunity | MESH:D001327 |
| 273 | 677-698 | Disease | denotes | chronic renal disease | MESH:D051436 |
| 274 | 819-829 | Disease | denotes | malignancy | MESH:D009369 |
| 275 | 890-898 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 276 | 929-946 | Disease | denotes | neurodegeneration | MESH:D019636 |
| 277 | 983-1000 | Disease | denotes | Alzheimer disease | MESH:D000544 |
MyTest
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32861199-31953710-26409835 | 588-590 | 31953710 | denotes | 46 |