PMC:7455778 / 18447-19735 JSONTXT

Annnotations TAB JSON ListView MergeView

    LitCovid-PD-FMA-UBERON

    {"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T33","span":{"begin":758,"end":764},"obj":"Body_part"},{"id":"T34","span":{"begin":968,"end":991},"obj":"Body_part"}],"attributes":[{"id":"A33","pred":"fma_id","subj":"T33","obj":"http://purl.org/sig/ont/fma/fma54437"},{"id":"A34","pred":"fma_id","subj":"T34","obj":"http://purl.org/sig/ont/fma/fma45661"}],"text":"The differential diagnosis of SARS-CoV-2 conjunctivitis includes other viral conjunctivitis such as adenoviral conjunctivitis, based on our findings (Table 5). 54.29% of conjunctivitis were completely unilateral, unlike adenoviral conjunctivitis where there is a greater tendency to bilateralization [11]. However, bilateral conjunctivitis in COVID-19 has also been described [3].\nTable 5 Differential diagnosis between conjunctivitis in COVID-19 patients and adenoviral conjunctivitis\nConjunctivitis in COVID-19 Adenoviral conjunctivitis\nOnset Abrupt Abrupt\nUnilateral/bilateral Unilateral ++\nBilateral + Unilateral or bilateral (often sequentially bilateral)\nConjunctival injection Mild or very mild Varies in severity\nFollicular reaction + +\nChemosis ± ±\nEyelid swelling and erythema – ±\nConjunctival petechiae /subconjunctival hemorrhage – ±\nDischarge + ++\nEpithelial punctate keratitis – ±\nCorneal infiltrates – ±\nMembrane/pseudomembrane formation – ±\nConcurrent upper respiratory tract infection ± ±\nSymptoms Very mild-mild Mild-severe\nNatural history Self-limited within 2–4 days Self-limited within 5–14 days (could get worse during the first days)\nPotential sequelae Not Known Severe cases: conjunctival scarring, symblepharon, subepithelial corneal infiltrates, decreased vision"}

    LitCovid-PD-UBERON

    {"project":"LitCovid-PD-UBERON","denotations":[{"id":"T12","span":{"begin":758,"end":764},"obj":"Body_part"},{"id":"T13","span":{"begin":968,"end":991},"obj":"Body_part"},{"id":"T14","span":{"begin":974,"end":991},"obj":"Body_part"}],"attributes":[{"id":"A12","pred":"uberon_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/UBERON_0001711"},{"id":"A13","pred":"uberon_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/UBERON_0001557"},{"id":"A14","pred":"uberon_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/UBERON_0000065"}],"text":"The differential diagnosis of SARS-CoV-2 conjunctivitis includes other viral conjunctivitis such as adenoviral conjunctivitis, based on our findings (Table 5). 54.29% of conjunctivitis were completely unilateral, unlike adenoviral conjunctivitis where there is a greater tendency to bilateralization [11]. However, bilateral conjunctivitis in COVID-19 has also been described [3].\nTable 5 Differential diagnosis between conjunctivitis in COVID-19 patients and adenoviral conjunctivitis\nConjunctivitis in COVID-19 Adenoviral conjunctivitis\nOnset Abrupt Abrupt\nUnilateral/bilateral Unilateral ++\nBilateral + Unilateral or bilateral (often sequentially bilateral)\nConjunctival injection Mild or very mild Varies in severity\nFollicular reaction + +\nChemosis ± ±\nEyelid swelling and erythema – ±\nConjunctival petechiae /subconjunctival hemorrhage – ±\nDischarge + ++\nEpithelial punctate keratitis – ±\nCorneal infiltrates – ±\nMembrane/pseudomembrane formation – ±\nConcurrent upper respiratory tract infection ± ±\nSymptoms Very mild-mild Mild-severe\nNatural history Self-limited within 2–4 days Self-limited within 5–14 days (could get worse during the first days)\nPotential sequelae Not Known Severe cases: conjunctival scarring, symblepharon, subepithelial corneal infiltrates, decreased vision"}

    LitCovid-PD-MONDO

    {"project":"LitCovid-PD-MONDO","denotations":[{"id":"T139","span":{"begin":30,"end":38},"obj":"Disease"},{"id":"T140","span":{"begin":41,"end":55},"obj":"Disease"},{"id":"T141","span":{"begin":71,"end":91},"obj":"Disease"},{"id":"T143","span":{"begin":77,"end":91},"obj":"Disease"},{"id":"T144","span":{"begin":111,"end":125},"obj":"Disease"},{"id":"T145","span":{"begin":170,"end":184},"obj":"Disease"},{"id":"T146","span":{"begin":231,"end":245},"obj":"Disease"},{"id":"T147","span":{"begin":325,"end":339},"obj":"Disease"},{"id":"T148","span":{"begin":343,"end":351},"obj":"Disease"},{"id":"T149","span":{"begin":420,"end":434},"obj":"Disease"},{"id":"T150","span":{"begin":438,"end":446},"obj":"Disease"},{"id":"T151","span":{"begin":471,"end":485},"obj":"Disease"},{"id":"T152","span":{"begin":486,"end":500},"obj":"Disease"},{"id":"T153","span":{"begin":504,"end":512},"obj":"Disease"},{"id":"T154","span":{"begin":524,"end":538},"obj":"Disease"},{"id":"T155","span":{"begin":872,"end":890},"obj":"Disease"},{"id":"T156","span":{"begin":881,"end":890},"obj":"Disease"},{"id":"T157","span":{"begin":974,"end":1001},"obj":"Disease"},{"id":"T158","span":{"begin":992,"end":1001},"obj":"Disease"},{"id":"T159","span":{"begin":1213,"end":1221},"obj":"Disease"}],"attributes":[{"id":"A139","pred":"mondo_id","subj":"T139","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A140","pred":"mondo_id","subj":"T140","obj":"http://purl.obolibrary.org/obo/MONDO_0003799"},{"id":"A141","pred":"mondo_id","subj":"T141","obj":"http://purl.obolibrary.org/obo/MONDO_0005634"},{"id":"A142","pred":"mondo_id","subj":"T141","obj":"http://purl.obolibrary.org/obo/MONDO_0043541"},{"id":"A143","pred":"mondo_id","subj":"T143","obj":"http://purl.obolibrary.org/obo/MONDO_0003799"},{"id":"A144","pred":"mondo_id","subj":"T144","obj":"http://purl.obolibrary.org/obo/MONDO_0003799"},{"id":"A145","pred":"mondo_id","subj":"T145","obj":"http://purl.obolibrary.org/obo/MONDO_0003799"},{"id":"A146","pred":"mondo_id","subj":"T146","obj":"http://purl.obolibrary.org/obo/MONDO_0003799"},{"id":"A147","pred":"mondo_id","subj":"T147","obj":"http://purl.obolibrary.org/obo/MONDO_0003799"},{"id":"A148","pred":"mondo_id","subj":"T148","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A149","pred":"mondo_id","subj":"T149","obj":"http://purl.obolibrary.org/obo/MONDO_0003799"},{"id":"A150","pred":"mondo_id","subj":"T150","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A151","pred":"mondo_id","subj":"T151","obj":"http://purl.obolibrary.org/obo/MONDO_0003799"},{"id":"A152","pred":"mondo_id","subj":"T152","obj":"http://purl.obolibrary.org/obo/MONDO_0003799"},{"id":"A153","pred":"mondo_id","subj":"T153","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A154","pred":"mondo_id","subj":"T154","obj":"http://purl.obolibrary.org/obo/MONDO_0003799"},{"id":"A155","pred":"mondo_id","subj":"T155","obj":"http://purl.obolibrary.org/obo/MONDO_0001466"},{"id":"A156","pred":"mondo_id","subj":"T156","obj":"http://purl.obolibrary.org/obo/MONDO_0003085"},{"id":"A157","pred":"mondo_id","subj":"T157","obj":"http://purl.obolibrary.org/obo/MONDO_0024355"},{"id":"A158","pred":"mondo_id","subj":"T158","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A159","pred":"mondo_id","subj":"T159","obj":"http://purl.obolibrary.org/obo/MONDO_0005594"}],"text":"The differential diagnosis of SARS-CoV-2 conjunctivitis includes other viral conjunctivitis such as adenoviral conjunctivitis, based on our findings (Table 5). 54.29% of conjunctivitis were completely unilateral, unlike adenoviral conjunctivitis where there is a greater tendency to bilateralization [11]. However, bilateral conjunctivitis in COVID-19 has also been described [3].\nTable 5 Differential diagnosis between conjunctivitis in COVID-19 patients and adenoviral conjunctivitis\nConjunctivitis in COVID-19 Adenoviral conjunctivitis\nOnset Abrupt Abrupt\nUnilateral/bilateral Unilateral ++\nBilateral + Unilateral or bilateral (often sequentially bilateral)\nConjunctival injection Mild or very mild Varies in severity\nFollicular reaction + +\nChemosis ± ±\nEyelid swelling and erythema – ±\nConjunctival petechiae /subconjunctival hemorrhage – ±\nDischarge + ++\nEpithelial punctate keratitis – ±\nCorneal infiltrates – ±\nMembrane/pseudomembrane formation – ±\nConcurrent upper respiratory tract infection ± ±\nSymptoms Very mild-mild Mild-severe\nNatural history Self-limited within 2–4 days Self-limited within 5–14 days (could get worse during the first days)\nPotential sequelae Not Known Severe cases: conjunctival scarring, symblepharon, subepithelial corneal infiltrates, decreased vision"}

    LitCovid-PD-CLO

    {"project":"LitCovid-PD-CLO","denotations":[{"id":"T146","span":{"begin":261,"end":262},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T147","span":{"begin":301,"end":303},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T148","span":{"begin":352,"end":355},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T149","span":{"begin":861,"end":871},"obj":"http://purl.obolibrary.org/obo/CL_0000066"},{"id":"T150","span":{"begin":919,"end":927},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T151","span":{"begin":1107,"end":1111},"obj":"http://purl.obolibrary.org/obo/CLO_0001406"}],"text":"The differential diagnosis of SARS-CoV-2 conjunctivitis includes other viral conjunctivitis such as adenoviral conjunctivitis, based on our findings (Table 5). 54.29% of conjunctivitis were completely unilateral, unlike adenoviral conjunctivitis where there is a greater tendency to bilateralization [11]. However, bilateral conjunctivitis in COVID-19 has also been described [3].\nTable 5 Differential diagnosis between conjunctivitis in COVID-19 patients and adenoviral conjunctivitis\nConjunctivitis in COVID-19 Adenoviral conjunctivitis\nOnset Abrupt Abrupt\nUnilateral/bilateral Unilateral ++\nBilateral + Unilateral or bilateral (often sequentially bilateral)\nConjunctival injection Mild or very mild Varies in severity\nFollicular reaction + +\nChemosis ± ±\nEyelid swelling and erythema – ±\nConjunctival petechiae /subconjunctival hemorrhage – ±\nDischarge + ++\nEpithelial punctate keratitis – ±\nCorneal infiltrates – ±\nMembrane/pseudomembrane formation – ±\nConcurrent upper respiratory tract infection ± ±\nSymptoms Very mild-mild Mild-severe\nNatural history Self-limited within 2–4 days Self-limited within 5–14 days (could get worse during the first days)\nPotential sequelae Not Known Severe cases: conjunctival scarring, symblepharon, subepithelial corneal infiltrates, decreased vision"}

    LitCovid-PD-HP

    {"project":"LitCovid-PD-HP","denotations":[{"id":"T101","span":{"begin":41,"end":55},"obj":"Phenotype"},{"id":"T102","span":{"begin":77,"end":91},"obj":"Phenotype"},{"id":"T103","span":{"begin":111,"end":125},"obj":"Phenotype"},{"id":"T104","span":{"begin":170,"end":184},"obj":"Phenotype"},{"id":"T105","span":{"begin":231,"end":245},"obj":"Phenotype"},{"id":"T106","span":{"begin":325,"end":339},"obj":"Phenotype"},{"id":"T107","span":{"begin":420,"end":434},"obj":"Phenotype"},{"id":"T108","span":{"begin":471,"end":485},"obj":"Phenotype"},{"id":"T109","span":{"begin":486,"end":500},"obj":"Phenotype"},{"id":"T110","span":{"begin":524,"end":538},"obj":"Phenotype"},{"id":"T111","span":{"begin":661,"end":683},"obj":"Phenotype"},{"id":"T112","span":{"begin":745,"end":753},"obj":"Phenotype"},{"id":"T113","span":{"begin":778,"end":786},"obj":"Phenotype"},{"id":"T114","span":{"begin":804,"end":813},"obj":"Phenotype"},{"id":"T115","span":{"begin":815,"end":841},"obj":"Phenotype"},{"id":"T116","span":{"begin":872,"end":890},"obj":"Phenotype"},{"id":"T117","span":{"begin":968,"end":1001},"obj":"Phenotype"},{"id":"T118","span":{"begin":1213,"end":1221},"obj":"Phenotype"},{"id":"T119","span":{"begin":1223,"end":1235},"obj":"Phenotype"}],"attributes":[{"id":"A101","pred":"hp_id","subj":"T101","obj":"http://purl.obolibrary.org/obo/HP_0000509"},{"id":"A102","pred":"hp_id","subj":"T102","obj":"http://purl.obolibrary.org/obo/HP_0000509"},{"id":"A103","pred":"hp_id","subj":"T103","obj":"http://purl.obolibrary.org/obo/HP_0000509"},{"id":"A104","pred":"hp_id","subj":"T104","obj":"http://purl.obolibrary.org/obo/HP_0000509"},{"id":"A105","pred":"hp_id","subj":"T105","obj":"http://purl.obolibrary.org/obo/HP_0000509"},{"id":"A106","pred":"hp_id","subj":"T106","obj":"http://purl.obolibrary.org/obo/HP_0000509"},{"id":"A107","pred":"hp_id","subj":"T107","obj":"http://purl.obolibrary.org/obo/HP_0000509"},{"id":"A108","pred":"hp_id","subj":"T108","obj":"http://purl.obolibrary.org/obo/HP_0000509"},{"id":"A109","pred":"hp_id","subj":"T109","obj":"http://purl.obolibrary.org/obo/HP_0000509"},{"id":"A110","pred":"hp_id","subj":"T110","obj":"http://purl.obolibrary.org/obo/HP_0000509"},{"id":"A111","pred":"hp_id","subj":"T111","obj":"http://purl.obolibrary.org/obo/HP_0030953"},{"id":"A112","pred":"hp_id","subj":"T112","obj":"http://purl.obolibrary.org/obo/HP_0012375"},{"id":"A113","pred":"hp_id","subj":"T113","obj":"http://purl.obolibrary.org/obo/HP_0010783"},{"id":"A114","pred":"hp_id","subj":"T114","obj":"http://purl.obolibrary.org/obo/HP_0000967"},{"id":"A115","pred":"hp_id","subj":"T115","obj":"http://purl.obolibrary.org/obo/HP_0011896"},{"id":"A116","pred":"hp_id","subj":"T116","obj":"http://purl.obolibrary.org/obo/HP_0011859"},{"id":"A117","pred":"hp_id","subj":"T117","obj":"http://purl.obolibrary.org/obo/HP_0002788"},{"id":"A118","pred":"hp_id","subj":"T118","obj":"http://purl.obolibrary.org/obo/HP_0100699"},{"id":"A119","pred":"hp_id","subj":"T119","obj":"http://purl.obolibrary.org/obo/HP_0430007"}],"text":"The differential diagnosis of SARS-CoV-2 conjunctivitis includes other viral conjunctivitis such as adenoviral conjunctivitis, based on our findings (Table 5). 54.29% of conjunctivitis were completely unilateral, unlike adenoviral conjunctivitis where there is a greater tendency to bilateralization [11]. However, bilateral conjunctivitis in COVID-19 has also been described [3].\nTable 5 Differential diagnosis between conjunctivitis in COVID-19 patients and adenoviral conjunctivitis\nConjunctivitis in COVID-19 Adenoviral conjunctivitis\nOnset Abrupt Abrupt\nUnilateral/bilateral Unilateral ++\nBilateral + Unilateral or bilateral (often sequentially bilateral)\nConjunctival injection Mild or very mild Varies in severity\nFollicular reaction + +\nChemosis ± ±\nEyelid swelling and erythema – ±\nConjunctival petechiae /subconjunctival hemorrhage – ±\nDischarge + ++\nEpithelial punctate keratitis – ±\nCorneal infiltrates – ±\nMembrane/pseudomembrane formation – ±\nConcurrent upper respiratory tract infection ± ±\nSymptoms Very mild-mild Mild-severe\nNatural history Self-limited within 2–4 days Self-limited within 5–14 days (could get worse during the first days)\nPotential sequelae Not Known Severe cases: conjunctival scarring, symblepharon, subepithelial corneal infiltrates, decreased vision"}

    LitCovid-PD-GO-BP

    {"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T6","span":{"begin":943,"end":952},"obj":"http://purl.obolibrary.org/obo/GO_0009058"},{"id":"T7","span":{"begin":1282,"end":1288},"obj":"http://purl.obolibrary.org/obo/GO_0007601"}],"text":"The differential diagnosis of SARS-CoV-2 conjunctivitis includes other viral conjunctivitis such as adenoviral conjunctivitis, based on our findings (Table 5). 54.29% of conjunctivitis were completely unilateral, unlike adenoviral conjunctivitis where there is a greater tendency to bilateralization [11]. However, bilateral conjunctivitis in COVID-19 has also been described [3].\nTable 5 Differential diagnosis between conjunctivitis in COVID-19 patients and adenoviral conjunctivitis\nConjunctivitis in COVID-19 Adenoviral conjunctivitis\nOnset Abrupt Abrupt\nUnilateral/bilateral Unilateral ++\nBilateral + Unilateral or bilateral (often sequentially bilateral)\nConjunctival injection Mild or very mild Varies in severity\nFollicular reaction + +\nChemosis ± ±\nEyelid swelling and erythema – ±\nConjunctival petechiae /subconjunctival hemorrhage – ±\nDischarge + ++\nEpithelial punctate keratitis – ±\nCorneal infiltrates – ±\nMembrane/pseudomembrane formation – ±\nConcurrent upper respiratory tract infection ± ±\nSymptoms Very mild-mild Mild-severe\nNatural history Self-limited within 2–4 days Self-limited within 5–14 days (could get worse during the first days)\nPotential sequelae Not Known Severe cases: conjunctival scarring, symblepharon, subepithelial corneal infiltrates, decreased vision"}

    LitCovid-sentences

    {"project":"LitCovid-sentences","denotations":[{"id":"T178","span":{"begin":0,"end":159},"obj":"Sentence"},{"id":"T179","span":{"begin":160,"end":305},"obj":"Sentence"},{"id":"T180","span":{"begin":306,"end":380},"obj":"Sentence"},{"id":"T181","span":{"begin":381,"end":485},"obj":"Sentence"},{"id":"T182","span":{"begin":486,"end":538},"obj":"Sentence"},{"id":"T183","span":{"begin":539,"end":558},"obj":"Sentence"},{"id":"T184","span":{"begin":559,"end":593},"obj":"Sentence"},{"id":"T185","span":{"begin":594,"end":660},"obj":"Sentence"},{"id":"T186","span":{"begin":661,"end":720},"obj":"Sentence"},{"id":"T187","span":{"begin":721,"end":744},"obj":"Sentence"},{"id":"T188","span":{"begin":745,"end":757},"obj":"Sentence"},{"id":"T189","span":{"begin":758,"end":790},"obj":"Sentence"},{"id":"T190","span":{"begin":791,"end":845},"obj":"Sentence"},{"id":"T191","span":{"begin":846,"end":860},"obj":"Sentence"},{"id":"T192","span":{"begin":861,"end":894},"obj":"Sentence"},{"id":"T193","span":{"begin":895,"end":918},"obj":"Sentence"},{"id":"T194","span":{"begin":919,"end":956},"obj":"Sentence"},{"id":"T195","span":{"begin":957,"end":1005},"obj":"Sentence"},{"id":"T196","span":{"begin":1006,"end":1041},"obj":"Sentence"},{"id":"T197","span":{"begin":1042,"end":1156},"obj":"Sentence"},{"id":"T198","span":{"begin":1157,"end":1288},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The differential diagnosis of SARS-CoV-2 conjunctivitis includes other viral conjunctivitis such as adenoviral conjunctivitis, based on our findings (Table 5). 54.29% of conjunctivitis were completely unilateral, unlike adenoviral conjunctivitis where there is a greater tendency to bilateralization [11]. However, bilateral conjunctivitis in COVID-19 has also been described [3].\nTable 5 Differential diagnosis between conjunctivitis in COVID-19 patients and adenoviral conjunctivitis\nConjunctivitis in COVID-19 Adenoviral conjunctivitis\nOnset Abrupt Abrupt\nUnilateral/bilateral Unilateral ++\nBilateral + Unilateral or bilateral (often sequentially bilateral)\nConjunctival injection Mild or very mild Varies in severity\nFollicular reaction + +\nChemosis ± ±\nEyelid swelling and erythema – ±\nConjunctival petechiae /subconjunctival hemorrhage – ±\nDischarge + ++\nEpithelial punctate keratitis – ±\nCorneal infiltrates – ±\nMembrane/pseudomembrane formation – ±\nConcurrent upper respiratory tract infection ± ±\nSymptoms Very mild-mild Mild-severe\nNatural history Self-limited within 2–4 days Self-limited within 5–14 days (could get worse during the first days)\nPotential sequelae Not Known Severe cases: conjunctival scarring, symblepharon, subepithelial corneal infiltrates, decreased vision"}

    2_test

    {"project":"2_test","denotations":[{"id":"32860573-32210533-45244302","span":{"begin":301,"end":303},"obj":"32210533"},{"id":"T79487","span":{"begin":301,"end":303},"obj":"32210533"}],"text":"The differential diagnosis of SARS-CoV-2 conjunctivitis includes other viral conjunctivitis such as adenoviral conjunctivitis, based on our findings (Table 5). 54.29% of conjunctivitis were completely unilateral, unlike adenoviral conjunctivitis where there is a greater tendency to bilateralization [11]. However, bilateral conjunctivitis in COVID-19 has also been described [3].\nTable 5 Differential diagnosis between conjunctivitis in COVID-19 patients and adenoviral conjunctivitis\nConjunctivitis in COVID-19 Adenoviral conjunctivitis\nOnset Abrupt Abrupt\nUnilateral/bilateral Unilateral ++\nBilateral + Unilateral or bilateral (often sequentially bilateral)\nConjunctival injection Mild or very mild Varies in severity\nFollicular reaction + +\nChemosis ± ±\nEyelid swelling and erythema – ±\nConjunctival petechiae /subconjunctival hemorrhage – ±\nDischarge + ++\nEpithelial punctate keratitis – ±\nCorneal infiltrates – ±\nMembrane/pseudomembrane formation – ±\nConcurrent upper respiratory tract infection ± ±\nSymptoms Very mild-mild Mild-severe\nNatural history Self-limited within 2–4 days Self-limited within 5–14 days (could get worse during the first days)\nPotential sequelae Not Known Severe cases: conjunctival scarring, symblepharon, subepithelial corneal infiltrates, decreased vision"}

    LitCovid-PMC-OGER-BB

    {"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T74","span":{"begin":170,"end":181},"obj":"SP_7"},{"id":"T76","span":{"begin":958,"end":984},"obj":"UBERON:0000970"},{"id":"T93","span":{"begin":897,"end":902},"obj":"NCBITaxon:10239"},{"id":"T132","span":{"begin":19,"end":29},"obj":"NCBITaxon:10508"},{"id":"T133","span":{"begin":139,"end":149},"obj":"NCBITaxon:10508"},{"id":"T134","span":{"begin":262,"end":270},"obj":"SP_7"},{"id":"T135","span":{"begin":355,"end":363},"obj":"SP_7"},{"id":"T136","span":{"begin":377,"end":387},"obj":"NCBITaxon:10508"},{"id":"T137","span":{"begin":420,"end":438},"obj":"SP_7"},{"id":"T138","span":{"begin":656,"end":662},"obj":"UBERON:0001711"},{"id":"T139","span":{"begin":708,"end":723},"obj":"UBERON:0003893"},{"id":"T140","span":{"begin":748,"end":757},"obj":"UBERON:0000483"},{"id":"T141","span":{"begin":847,"end":870},"obj":"UBERON:0001557"},{"id":"T142","span":{"begin":1069,"end":1081},"obj":"UBERON:0001811"},{"id":"T143","span":{"begin":1106,"end":1126},"obj":"UBERON:0001772"},{"id":"T144","span":{"begin":1150,"end":1156},"obj":"GO:0007601"},{"id":"T145","span":{"begin":1214,"end":1222},"obj":"SP_7"},{"id":"T146","span":{"begin":1236,"end":1247},"obj":"NCBITaxon:10508"}],"text":"The differential diagnosis of SARS-CoV-2 conjunctivitis includes other viral conjunctivitis such as adenoviral conjunctivitis, based on our findings (Table 5). 54.29% of conjunctivitis were completely unilateral, unlike adenoviral conjunctivitis where there is a greater tendency to bilateralization [11]. However, bilateral conjunctivitis in COVID-19 has also been described [3].\nTable 5 Differential diagnosis between conjunctivitis in COVID-19 patients and adenoviral conjunctivitis\nConjunctivitis in COVID-19 Adenoviral conjunctivitis\nOnset Abrupt Abrupt\nUnilateral/bilateral Unilateral ++\nBilateral + Unilateral or bilateral (often sequentially bilateral)\nConjunctival injection Mild or very mild Varies in severity\nFollicular reaction + +\nChemosis ± ±\nEyelid swelling and erythema – ±\nConjunctival petechiae /subconjunctival hemorrhage – ±\nDischarge + ++\nEpithelial punctate keratitis – ±\nCorneal infiltrates – ±\nMembrane/pseudomembrane formation – ±\nConcurrent upper respiratory tract infection ± ±\nSymptoms Very mild-mild Mild-severe\nNatural history Self-limited within 2–4 days Self-limited within 5–14 days (could get worse during the first days)\nPotential sequelae Not Known Severe cases: conjunctival scarring, symblepharon, subepithelial corneal infiltrates, decreased vision"}

    LitCovid-PubTator

    {"project":"LitCovid-PubTator","denotations":[{"id":"488","span":{"begin":486,"end":500},"obj":"Disease"},{"id":"489","span":{"begin":504,"end":512},"obj":"Disease"},{"id":"490","span":{"begin":513,"end":558},"obj":"Disease"},{"id":"491","span":{"begin":758,"end":773},"obj":"Disease"},{"id":"492","span":{"begin":778,"end":786},"obj":"Disease"},{"id":"493","span":{"begin":815,"end":841},"obj":"Disease"},{"id":"494","span":{"begin":968,"end":1001},"obj":"Disease"},{"id":"495","span":{"begin":1237,"end":1270},"obj":"Disease"},{"id":"500","span":{"begin":447,"end":455},"obj":"Species"},{"id":"501","span":{"begin":420,"end":434},"obj":"Disease"},{"id":"502","span":{"begin":438,"end":446},"obj":"Disease"},{"id":"503","span":{"begin":471,"end":485},"obj":"Disease"},{"id":"511","span":{"begin":30,"end":55},"obj":"Disease"},{"id":"512","span":{"begin":71,"end":91},"obj":"Disease"},{"id":"513","span":{"begin":111,"end":125},"obj":"Disease"},{"id":"514","span":{"begin":170,"end":184},"obj":"Disease"},{"id":"515","span":{"begin":231,"end":245},"obj":"Disease"},{"id":"516","span":{"begin":325,"end":339},"obj":"Disease"},{"id":"517","span":{"begin":343,"end":351},"obj":"Disease"}],"attributes":[{"id":"A488","pred":"tao:has_database_id","subj":"488","obj":"MESH:D003231"},{"id":"A489","pred":"tao:has_database_id","subj":"489","obj":"MESH:C000657245"},{"id":"A490","pred":"tao:has_database_id","subj":"490","obj":"MESH:D000033"},{"id":"A491","pred":"tao:has_database_id","subj":"491","obj":"MESH:D005141"},{"id":"A492","pred":"tao:has_database_id","subj":"492","obj":"MESH:D004890"},{"id":"A493","pred":"tao:has_database_id","subj":"493","obj":"MESH:D006470"},{"id":"A494","pred":"tao:has_database_id","subj":"494","obj":"MESH:D012141"},{"id":"A495","pred":"tao:has_database_id","subj":"495","obj":"MESH:C567547"},{"id":"A500","pred":"tao:has_database_id","subj":"500","obj":"Tax:9606"},{"id":"A501","pred":"tao:has_database_id","subj":"501","obj":"MESH:D003231"},{"id":"A502","pred":"tao:has_database_id","subj":"502","obj":"MESH:C000657245"},{"id":"A503","pred":"tao:has_database_id","subj":"503","obj":"MESH:D003231"},{"id":"A511","pred":"tao:has_database_id","subj":"511","obj":"MESH:C000657245"},{"id":"A513","pred":"tao:has_database_id","subj":"513","obj":"MESH:D003231"},{"id":"A514","pred":"tao:has_database_id","subj":"514","obj":"MESH:D003231"},{"id":"A515","pred":"tao:has_database_id","subj":"515","obj":"MESH:D003231"},{"id":"A516","pred":"tao:has_database_id","subj":"516","obj":"MESH:D003231"},{"id":"A517","pred":"tao:has_database_id","subj":"517","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The differential diagnosis of SARS-CoV-2 conjunctivitis includes other viral conjunctivitis such as adenoviral conjunctivitis, based on our findings (Table 5). 54.29% of conjunctivitis were completely unilateral, unlike adenoviral conjunctivitis where there is a greater tendency to bilateralization [11]. However, bilateral conjunctivitis in COVID-19 has also been described [3].\nTable 5 Differential diagnosis between conjunctivitis in COVID-19 patients and adenoviral conjunctivitis\nConjunctivitis in COVID-19 Adenoviral conjunctivitis\nOnset Abrupt Abrupt\nUnilateral/bilateral Unilateral ++\nBilateral + Unilateral or bilateral (often sequentially bilateral)\nConjunctival injection Mild or very mild Varies in severity\nFollicular reaction + +\nChemosis ± ±\nEyelid swelling and erythema – ±\nConjunctival petechiae /subconjunctival hemorrhage – ±\nDischarge + ++\nEpithelial punctate keratitis – ±\nCorneal infiltrates – ±\nMembrane/pseudomembrane formation – ±\nConcurrent upper respiratory tract infection ± ±\nSymptoms Very mild-mild Mild-severe\nNatural history Self-limited within 2–4 days Self-limited within 5–14 days (could get worse during the first days)\nPotential sequelae Not Known Severe cases: conjunctival scarring, symblepharon, subepithelial corneal infiltrates, decreased vision"}