PMC:7455777 / 2308-3421 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T14","span":{"begin":156,"end":171},"obj":"Body_part"},{"id":"T15","span":{"begin":258,"end":265},"obj":"Body_part"},{"id":"T16","span":{"begin":710,"end":722},"obj":"Body_part"}],"attributes":[{"id":"A14","pred":"fma_id","subj":"T14","obj":"http://purl.org/sig/ont/fma/fma61830"},{"id":"A15","pred":"fma_id","subj":"T15","obj":"http://purl.org/sig/ont/fma/fma54527"},{"id":"A16","pred":"fma_id","subj":"T16","obj":"http://purl.org/sig/ont/fma/fma83929"}],"text":"Manifestations Presentations Neuropathological findings Type of study References\nEncephalitis/meningitis Three out of six patients presented with somnolent Cerebral cortex encephalitis with perivascular and parenchymal inflammatory infiltrates, and shrunken neurons Correspondence [5]\nEncephalopathy Four out of 18 patients presented with myalgia, headache, and decreased taste, progressed to consciousness and multiorgan failure Hypoxic changes with no specific pathology Retrospective study [6]\nAcute disseminated encephalomyelitis Fatigue and exertional dyspnea, progressed to shock state, respiratory failure Features resembling both vascular and demyelinating aetiologies among with range of sub-cortical white matter pathology Case report [7]\nAcute cerebrovascular disease 17 patients presented with cerebral ischaemia, five with intracerebral haemorrhage and one with leukoencephalopathy of posterior reversible encephalopathy Thrombotic microangiopathy and endothelial injury Retrospective study [8]\nTwo patient presented with coma and multiorgan failure Microthrombi and acute infarcts Correspondence [9]"}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T12","span":{"begin":156,"end":171},"obj":"Body_part"},{"id":"T13","span":{"begin":165,"end":171},"obj":"Body_part"},{"id":"T14","span":{"begin":710,"end":722},"obj":"Body_part"}],"attributes":[{"id":"A12","pred":"uberon_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/UBERON_0000956"},{"id":"A13","pred":"uberon_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/UBERON_0001851"},{"id":"A14","pred":"uberon_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/UBERON_0002316"}],"text":"Manifestations Presentations Neuropathological findings Type of study References\nEncephalitis/meningitis Three out of six patients presented with somnolent Cerebral cortex encephalitis with perivascular and parenchymal inflammatory infiltrates, and shrunken neurons Correspondence [5]\nEncephalopathy Four out of 18 patients presented with myalgia, headache, and decreased taste, progressed to consciousness and multiorgan failure Hypoxic changes with no specific pathology Retrospective study [6]\nAcute disseminated encephalomyelitis Fatigue and exertional dyspnea, progressed to shock state, respiratory failure Features resembling both vascular and demyelinating aetiologies among with range of sub-cortical white matter pathology Case report [7]\nAcute cerebrovascular disease 17 patients presented with cerebral ischaemia, five with intracerebral haemorrhage and one with leukoencephalopathy of posterior reversible encephalopathy Thrombotic microangiopathy and endothelial injury Retrospective study [8]\nTwo patient presented with coma and multiorgan failure Microthrombi and acute infarcts Correspondence [9]"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T27","span":{"begin":81,"end":93},"obj":"Disease"},{"id":"T28","span":{"begin":94,"end":104},"obj":"Disease"},{"id":"T30","span":{"begin":172,"end":184},"obj":"Disease"},{"id":"T31","span":{"begin":285,"end":299},"obj":"Disease"},{"id":"T32","span":{"begin":411,"end":429},"obj":"Disease"},{"id":"T33","span":{"begin":497,"end":533},"obj":"Disease"},{"id":"T34","span":{"begin":516,"end":533},"obj":"Disease"},{"id":"T35","span":{"begin":593,"end":612},"obj":"Disease"},{"id":"T36","span":{"begin":755,"end":778},"obj":"Disease"},{"id":"T37","span":{"begin":919,"end":933},"obj":"Disease"},{"id":"T38","span":{"begin":934,"end":960},"obj":"Disease"},{"id":"T39","span":{"begin":977,"end":983},"obj":"Disease"},{"id":"T40","span":{"begin":1044,"end":1062},"obj":"Disease"}],"attributes":[{"id":"A27","pred":"mondo_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/MONDO_0019956"},{"id":"A28","pred":"mondo_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/MONDO_0004796"},{"id":"A29","pred":"mondo_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/MONDO_0021108"},{"id":"A30","pred":"mondo_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/MONDO_0019956"},{"id":"A31","pred":"mondo_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/MONDO_0005560"},{"id":"A32","pred":"mondo_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/MONDO_0043726"},{"id":"A33","pred":"mondo_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/MONDO_0019383"},{"id":"A34","pred":"mondo_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/MONDO_0005156"},{"id":"A35","pred":"mondo_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/MONDO_0021113"},{"id":"A36","pred":"mondo_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/MONDO_0011057"},{"id":"A37","pred":"mondo_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/MONDO_0005560"},{"id":"A38","pred":"mondo_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/MONDO_0019737"},{"id":"A39","pred":"mondo_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/MONDO_0021178"},{"id":"A40","pred":"mondo_id","subj":"T40","obj":"http://purl.obolibrary.org/obo/MONDO_0043726"}],"text":"Manifestations Presentations Neuropathological findings Type of study References\nEncephalitis/meningitis Three out of six patients presented with somnolent Cerebral cortex encephalitis with perivascular and parenchymal inflammatory infiltrates, and shrunken neurons Correspondence [5]\nEncephalopathy Four out of 18 patients presented with myalgia, headache, and decreased taste, progressed to consciousness and multiorgan failure Hypoxic changes with no specific pathology Retrospective study [6]\nAcute disseminated encephalomyelitis Fatigue and exertional dyspnea, progressed to shock state, respiratory failure Features resembling both vascular and demyelinating aetiologies among with range of sub-cortical white matter pathology Case report [7]\nAcute cerebrovascular disease 17 patients presented with cerebral ischaemia, five with intracerebral haemorrhage and one with leukoencephalopathy of posterior reversible encephalopathy Thrombotic microangiopathy and endothelial injury Retrospective study [8]\nTwo patient presented with coma and multiorgan failure Microthrombi and acute infarcts Correspondence [9]"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T41","span":{"begin":156,"end":171},"obj":"http://purl.obolibrary.org/obo/UBERON_0000956"},{"id":"T42","span":{"begin":312,"end":314},"obj":"http://purl.obolibrary.org/obo/CLO_0050510"},{"id":"T43","span":{"begin":898,"end":907},"obj":"http://purl.obolibrary.org/obo/UBERON_0001353"}],"text":"Manifestations Presentations Neuropathological findings Type of study References\nEncephalitis/meningitis Three out of six patients presented with somnolent Cerebral cortex encephalitis with perivascular and parenchymal inflammatory infiltrates, and shrunken neurons Correspondence [5]\nEncephalopathy Four out of 18 patients presented with myalgia, headache, and decreased taste, progressed to consciousness and multiorgan failure Hypoxic changes with no specific pathology Retrospective study [6]\nAcute disseminated encephalomyelitis Fatigue and exertional dyspnea, progressed to shock state, respiratory failure Features resembling both vascular and demyelinating aetiologies among with range of sub-cortical white matter pathology Case report [7]\nAcute cerebrovascular disease 17 patients presented with cerebral ischaemia, five with intracerebral haemorrhage and one with leukoencephalopathy of posterior reversible encephalopathy Thrombotic microangiopathy and endothelial injury Retrospective study [8]\nTwo patient presented with coma and multiorgan failure Microthrombi and acute infarcts Correspondence [9]"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T10","span":{"begin":81,"end":93},"obj":"Phenotype"},{"id":"T11","span":{"begin":94,"end":104},"obj":"Phenotype"},{"id":"T12","span":{"begin":172,"end":184},"obj":"Phenotype"},{"id":"T13","span":{"begin":285,"end":299},"obj":"Phenotype"},{"id":"T14","span":{"begin":339,"end":346},"obj":"Phenotype"},{"id":"T15","span":{"begin":348,"end":356},"obj":"Phenotype"},{"id":"T16","span":{"begin":362,"end":377},"obj":"Phenotype"},{"id":"T17","span":{"begin":534,"end":541},"obj":"Phenotype"},{"id":"T18","span":{"begin":546,"end":564},"obj":"Phenotype"},{"id":"T19","span":{"begin":580,"end":585},"obj":"Phenotype"},{"id":"T20","span":{"begin":593,"end":612},"obj":"Phenotype"},{"id":"T21","span":{"begin":651,"end":664},"obj":"Phenotype"},{"id":"T22","span":{"begin":875,"end":894},"obj":"Phenotype"},{"id":"T23","span":{"begin":919,"end":933},"obj":"Phenotype"},{"id":"T24","span":{"begin":1035,"end":1039},"obj":"Phenotype"}],"attributes":[{"id":"A10","pred":"hp_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/HP_0002383"},{"id":"A11","pred":"hp_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/HP_0001287"},{"id":"A12","pred":"hp_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/HP_0002383"},{"id":"A13","pred":"hp_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/HP_0001298"},{"id":"A14","pred":"hp_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/HP_0003326"},{"id":"A15","pred":"hp_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/HP_0002315"},{"id":"A16","pred":"hp_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/HP_0000224"},{"id":"A17","pred":"hp_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/HP_0012378"},{"id":"A18","pred":"hp_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/HP_0002875"},{"id":"A19","pred":"hp_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/HP_0031273"},{"id":"A20","pred":"hp_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/HP_0002878"},{"id":"A21","pred":"hp_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/HP_0011096"},{"id":"A22","pred":"hp_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/HP_0002352"},{"id":"A23","pred":"hp_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/HP_0001298"},{"id":"A24","pred":"hp_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/HP_0001259"}],"text":"Manifestations Presentations Neuropathological findings Type of study References\nEncephalitis/meningitis Three out of six patients presented with somnolent Cerebral cortex encephalitis with perivascular and parenchymal inflammatory infiltrates, and shrunken neurons Correspondence [5]\nEncephalopathy Four out of 18 patients presented with myalgia, headache, and decreased taste, progressed to consciousness and multiorgan failure Hypoxic changes with no specific pathology Retrospective study [6]\nAcute disseminated encephalomyelitis Fatigue and exertional dyspnea, progressed to shock state, respiratory failure Features resembling both vascular and demyelinating aetiologies among with range of sub-cortical white matter pathology Case report [7]\nAcute cerebrovascular disease 17 patients presented with cerebral ischaemia, five with intracerebral haemorrhage and one with leukoencephalopathy of posterior reversible encephalopathy Thrombotic microangiopathy and endothelial injury Retrospective study [8]\nTwo patient presented with coma and multiorgan failure Microthrombi and acute infarcts Correspondence [9]"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T1","span":{"begin":372,"end":377},"obj":"http://purl.obolibrary.org/obo/GO_0050909"}],"text":"Manifestations Presentations Neuropathological findings Type of study References\nEncephalitis/meningitis Three out of six patients presented with somnolent Cerebral cortex encephalitis with perivascular and parenchymal inflammatory infiltrates, and shrunken neurons Correspondence [5]\nEncephalopathy Four out of 18 patients presented with myalgia, headache, and decreased taste, progressed to consciousness and multiorgan failure Hypoxic changes with no specific pathology Retrospective study [6]\nAcute disseminated encephalomyelitis Fatigue and exertional dyspnea, progressed to shock state, respiratory failure Features resembling both vascular and demyelinating aetiologies among with range of sub-cortical white matter pathology Case report [7]\nAcute cerebrovascular disease 17 patients presented with cerebral ischaemia, five with intracerebral haemorrhage and one with leukoencephalopathy of posterior reversible encephalopathy Thrombotic microangiopathy and endothelial injury Retrospective study [8]\nTwo patient presented with coma and multiorgan failure Microthrombi and acute infarcts Correspondence [9]"}

{"project":"LitCovid-sentences","denotations":[{"id":"T16","span":{"begin":0,"end":80},"obj":"Sentence"},{"id":"T17","span":{"begin":81,"end":284},"obj":"Sentence"},{"id":"T18","span":{"begin":285,"end":496},"obj":"Sentence"},{"id":"T19","span":{"begin":497,"end":748},"obj":"Sentence"},{"id":"T20","span":{"begin":749,"end":1007},"obj":"Sentence"},{"id":"T21","span":{"begin":1008,"end":1113},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Manifestations Presentations Neuropathological findings Type of study References\nEncephalitis/meningitis Three out of six patients presented with somnolent Cerebral cortex encephalitis with perivascular and parenchymal inflammatory infiltrates, and shrunken neurons Correspondence [5]\nEncephalopathy Four out of 18 patients presented with myalgia, headache, and decreased taste, progressed to consciousness and multiorgan failure Hypoxic changes with no specific pathology Retrospective study [6]\nAcute disseminated encephalomyelitis Fatigue and exertional dyspnea, progressed to shock state, respiratory failure Features resembling both vascular and demyelinating aetiologies among with range of sub-cortical white matter pathology Case report [7]\nAcute cerebrovascular disease 17 patients presented with cerebral ischaemia, five with intracerebral haemorrhage and one with leukoencephalopathy of posterior reversible encephalopathy Thrombotic microangiopathy and endothelial injury Retrospective study [8]\nTwo patient presented with coma and multiorgan failure Microthrombi and acute infarcts Correspondence [9]"}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T50","span":{"begin":165,"end":171},"obj":"UBERON:0001851"},{"id":"T51","span":{"begin":190,"end":202},"obj":"UBERON:0014930"},{"id":"T52","span":{"begin":207,"end":218},"obj":"UBERON:0008987"},{"id":"T53","span":{"begin":258,"end":280},"obj":"CL:0000540"},{"id":"T54","span":{"begin":372,"end":377},"obj":"GO:0050909"},{"id":"T55","span":{"begin":411,"end":421},"obj":"UBERON:0000062"},{"id":"T56","span":{"begin":593,"end":604},"obj":"UBERON:0001004"},{"id":"T57","span":{"begin":701,"end":709},"obj":"UBERON:0001851"},{"id":"T58","span":{"begin":710,"end":722},"obj":"UBERON:0002316"},{"id":"T59","span":{"begin":755,"end":770},"obj":"UBERON:0002037"},{"id":"T60","span":{"begin":806,"end":814},"obj":"UBERON:0001893"},{"id":"T61","span":{"begin":965,"end":976},"obj":"UBERON:0001986"},{"id":"T62","span":{"begin":1044,"end":1054},"obj":"UBERON:0000062"},{"id":"T78205","span":{"begin":436,"end":441},"obj":"NCBITaxon:10239"},{"id":"T31513","span":{"begin":443,"end":447},"obj":"GO:0006955"},{"id":"T35827","span":{"begin":448,"end":453},"obj":"UBERON:0002405;GO:0006955"},{"id":"T24974","span":{"begin":454,"end":462},"obj":"GO:0006955"},{"id":"T55916","span":{"begin":506,"end":515},"obj":"UBERON:0002048"},{"id":"T47982","span":{"begin":606,"end":611},"obj":"NCBITaxon:10239"},{"id":"T57685","span":{"begin":629,"end":632},"obj":"UBERON:0001017"},{"id":"T17278","span":{"begin":657,"end":664},"obj":"CL:0000540"},{"id":"T57698","span":{"begin":669,"end":680},"obj":"CL:0000125"},{"id":"T64355","span":{"begin":707,"end":719},"obj":"UBERON:0001016"},{"id":"T54808","span":{"begin":796,"end":799},"obj":"UBERON:0001017"},{"id":"T50105","span":{"begin":837,"end":847},"obj":"SP_7"},{"id":"T87508","span":{"begin":975,"end":983},"obj":"SP_10"},{"id":"T16890","span":{"begin":1055,"end":1060},"obj":"NCBITaxon:10239"},{"id":"T50263","span":{"begin":1086,"end":1089},"obj":"UBERON:0001017"}],"text":"Manifestations Presentations Neuropathological findings Type of study References\nEncephalitis/meningitis Three out of six patients presented with somnolent Cerebral cortex encephalitis with perivascular and parenchymal inflammatory infiltrates, and shrunken neurons Correspondence [5]\nEncephalopathy Four out of 18 patients presented with myalgia, headache, and decreased taste, progressed to consciousness and multiorgan failure Hypoxic changes with no specific pathology Retrospective study [6]\nAcute disseminated encephalomyelitis Fatigue and exertional dyspnea, progressed to shock state, respiratory failure Features resembling both vascular and demyelinating aetiologies among with range of sub-cortical white matter pathology Case report [7]\nAcute cerebrovascular disease 17 patients presented with cerebral ischaemia, five with intracerebral haemorrhage and one with leukoencephalopathy of posterior reversible encephalopathy Thrombotic microangiopathy and endothelial injury Retrospective study [8]\nTwo patient presented with coma and multiorgan failure Microthrombi and acute infarcts Correspondence [9]"}

{"project":"LitCovid-PubTator","denotations":[{"id":"57","span":{"begin":122,"end":130},"obj":"Species"},{"id":"58","span":{"begin":315,"end":323},"obj":"Species"},{"id":"59","span":{"begin":782,"end":790},"obj":"Species"},{"id":"60","span":{"begin":1012,"end":1019},"obj":"Species"},{"id":"61","span":{"begin":81,"end":104},"obj":"Disease"},{"id":"62","span":{"begin":146,"end":184},"obj":"Disease"},{"id":"63","span":{"begin":249,"end":299},"obj":"Disease"},{"id":"64","span":{"begin":339,"end":346},"obj":"Disease"},{"id":"65","span":{"begin":348,"end":356},"obj":"Disease"},{"id":"66","span":{"begin":411,"end":437},"obj":"Disease"},{"id":"67","span":{"begin":497,"end":541},"obj":"Disease"},{"id":"68","span":{"begin":546,"end":564},"obj":"Disease"},{"id":"69","span":{"begin":593,"end":612},"obj":"Disease"},{"id":"70","span":{"begin":749,"end":778},"obj":"Disease"},{"id":"71","span":{"begin":806,"end":824},"obj":"Disease"},{"id":"72","span":{"begin":836,"end":861},"obj":"Disease"},{"id":"73","span":{"begin":875,"end":894},"obj":"Disease"},{"id":"74","span":{"begin":919,"end":960},"obj":"Disease"},{"id":"75","span":{"begin":965,"end":983},"obj":"Disease"},{"id":"76","span":{"begin":1035,"end":1075},"obj":"Disease"},{"id":"77","span":{"begin":1086,"end":1094},"obj":"Disease"}],"attributes":[{"id":"A57","pred":"tao:has_database_id","subj":"57","obj":"Tax:9606"},{"id":"A58","pred":"tao:has_database_id","subj":"58","obj":"Tax:9606"},{"id":"A59","pred":"tao:has_database_id","subj":"59","obj":"Tax:9606"},{"id":"A60","pred":"tao:has_database_id","subj":"60","obj":"Tax:9606"},{"id":"A61","pred":"tao:has_database_id","subj":"61","obj":"MESH:D004660"},{"id":"A62","pred":"tao:has_database_id","subj":"62","obj":"MESH:D006970"},{"id":"A63","pred":"tao:has_database_id","subj":"63","obj":"MESH:D001927"},{"id":"A64","pred":"tao:has_database_id","subj":"64","obj":"MESH:D063806"},{"id":"A65","pred":"tao:has_database_id","subj":"65","obj":"MESH:D006261"},{"id":"A66","pred":"tao:has_database_id","subj":"66","obj":"MESH:D009102"},{"id":"A67","pred":"tao:has_database_id","subj":"67","obj":"MESH:D004673"},{"id":"A68","pred":"tao:has_database_id","subj":"68","obj":"MESH:D004417"},{"id":"A69","pred":"tao:has_database_id","subj":"69","obj":"MESH:D012131"},{"id":"A70","pred":"tao:has_database_id","subj":"70","obj":"MESH:D002561"},{"id":"A71","pred":"tao:has_database_id","subj":"71","obj":"MESH:D002545"},{"id":"A72","pred":"tao:has_database_id","subj":"72","obj":"MESH:D002543"},{"id":"A73","pred":"tao:has_database_id","subj":"73","obj":"MESH:D056784"},{"id":"A74","pred":"tao:has_database_id","subj":"74","obj":"MESH:D057049"},{"id":"A75","pred":"tao:has_database_id","subj":"75","obj":"MESH:D014947"},{"id":"A76","pred":"tao:has_database_id","subj":"76","obj":"MESH:D003128"},{"id":"A77","pred":"tao:has_database_id","subj":"77","obj":"MESH:D007238"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Manifestations Presentations Neuropathological findings Type of study References\nEncephalitis/meningitis Three out of six patients presented with somnolent Cerebral cortex encephalitis with perivascular and parenchymal inflammatory infiltrates, and shrunken neurons Correspondence [5]\nEncephalopathy Four out of 18 patients presented with myalgia, headache, and decreased taste, progressed to consciousness and multiorgan failure Hypoxic changes with no specific pathology Retrospective study [6]\nAcute disseminated encephalomyelitis Fatigue and exertional dyspnea, progressed to shock state, respiratory failure Features resembling both vascular and demyelinating aetiologies among with range of sub-cortical white matter pathology Case report [7]\nAcute cerebrovascular disease 17 patients presented with cerebral ischaemia, five with intracerebral haemorrhage and one with leukoencephalopathy of posterior reversible encephalopathy Thrombotic microangiopathy and endothelial injury Retrospective study [8]\nTwo patient presented with coma and multiorgan failure Microthrombi and acute infarcts Correspondence [9]"}