PMC:7454258 / 202104-203872 JSONTXT

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T8","span":{"begin":24,"end":29},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T9","span":{"begin":53,"end":54},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T10","span":{"begin":276,"end":281},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T11","span":{"begin":331,"end":332},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T12","span":{"begin":350,"end":351},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T13","span":{"begin":405,"end":406},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T14","span":{"begin":437,"end":438},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T15","span":{"begin":540,"end":550},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T16","span":{"begin":569,"end":570},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T17","span":{"begin":613,"end":614},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T18","span":{"begin":808,"end":809},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T19","span":{"begin":956,"end":957},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T20","span":{"begin":1408,"end":1409},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T21","span":{"begin":1457,"end":1467},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T22","span":{"begin":1483,"end":1488},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T23","span":{"begin":1552,"end":1557},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T24","span":{"begin":1609,"end":1614},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"}],"text":"As one example, the NIH Human Microbiome Project was a trans-NIH initiative supported by the NIH Common Fund from 2007 to 2016 (334). This project aimed to expand science on the microbiome. Initially funded as an initiative of the NIH Roadmap for Biomedical Research, the NIH Human Microbiome Project was originally established as a 5-y project with a budget of $150 million (335). The project began with a “jumpstart” phase in 2007 and a set of grants was funded in mid-2009 and additional demonstration project grants were awarded. These activities were supported by a Data Analysis and Coordination Center and a set of additional grants was awarded for developing new technologies, new software tools, and studying the ethical, legal, and social implications of this work. The grantees worked together in a highly cooperative consortium. Ultimately, this 10-y $215 million project spanned \u003e20 of the NIH institutes, centers, and offices and resulted in a \u003e40-fold increase in nonproject investment in microbiome research (336). That is, individual or multiple institutes, centers, and offices used program announcements or request for applications. Some of these funding mechanisms were supported by the Common Fund and others were additional commitments by the participating NIH institutes, centers, and offices from their own budgets. The Trans-NIH Microbiome Working Group established in 2012 provided a forum for coordinating NIH extramural research activities related to the human microbiome and continues to coordinate this work after the NIH Human Microbiome Project was completed. Notably, the NIH Human Microbiome Project identified several potential priority areas around food and the microbiome, but these topics have not yet been systematically pursued."}

{"project":"LitCovid-PubTator","denotations":[{"id":"881","span":{"begin":24,"end":40},"obj":"Species"},{"id":"882","span":{"begin":276,"end":292},"obj":"Species"},{"id":"883","span":{"begin":1483,"end":1499},"obj":"Species"},{"id":"884","span":{"begin":1552,"end":1568},"obj":"Species"},{"id":"885","span":{"begin":1609,"end":1625},"obj":"Species"}],"attributes":[{"id":"A881","pred":"tao:has_database_id","subj":"881","obj":"Tax:646099"},{"id":"A882","pred":"tao:has_database_id","subj":"882","obj":"Tax:646099"},{"id":"A883","pred":"tao:has_database_id","subj":"883","obj":"Tax:646099"},{"id":"A884","pred":"tao:has_database_id","subj":"884","obj":"Tax:646099"},{"id":"A885","pred":"tao:has_database_id","subj":"885","obj":"Tax:646099"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"As one example, the NIH Human Microbiome Project was a trans-NIH initiative supported by the NIH Common Fund from 2007 to 2016 (334). This project aimed to expand science on the microbiome. Initially funded as an initiative of the NIH Roadmap for Biomedical Research, the NIH Human Microbiome Project was originally established as a 5-y project with a budget of $150 million (335). The project began with a “jumpstart” phase in 2007 and a set of grants was funded in mid-2009 and additional demonstration project grants were awarded. These activities were supported by a Data Analysis and Coordination Center and a set of additional grants was awarded for developing new technologies, new software tools, and studying the ethical, legal, and social implications of this work. The grantees worked together in a highly cooperative consortium. Ultimately, this 10-y $215 million project spanned \u003e20 of the NIH institutes, centers, and offices and resulted in a \u003e40-fold increase in nonproject investment in microbiome research (336). That is, individual or multiple institutes, centers, and offices used program announcements or request for applications. Some of these funding mechanisms were supported by the Common Fund and others were additional commitments by the participating NIH institutes, centers, and offices from their own budgets. The Trans-NIH Microbiome Working Group established in 2012 provided a forum for coordinating NIH extramural research activities related to the human microbiome and continues to coordinate this work after the NIH Human Microbiome Project was completed. Notably, the NIH Human Microbiome Project identified several potential priority areas around food and the microbiome, but these topics have not yet been systematically pursued."}

{"project":"LitCovid-sentences","denotations":[{"id":"T1108","span":{"begin":0,"end":133},"obj":"Sentence"},{"id":"T1109","span":{"begin":134,"end":189},"obj":"Sentence"},{"id":"T1110","span":{"begin":190,"end":381},"obj":"Sentence"},{"id":"T1111","span":{"begin":382,"end":533},"obj":"Sentence"},{"id":"T1112","span":{"begin":534,"end":775},"obj":"Sentence"},{"id":"T1113","span":{"begin":776,"end":840},"obj":"Sentence"},{"id":"T1114","span":{"begin":841,"end":1030},"obj":"Sentence"},{"id":"T1115","span":{"begin":1031,"end":1151},"obj":"Sentence"},{"id":"T1116","span":{"begin":1152,"end":1339},"obj":"Sentence"},{"id":"T1117","span":{"begin":1340,"end":1591},"obj":"Sentence"},{"id":"T1118","span":{"begin":1592,"end":1768},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"As one example, the NIH Human Microbiome Project was a trans-NIH initiative supported by the NIH Common Fund from 2007 to 2016 (334). This project aimed to expand science on the microbiome. Initially funded as an initiative of the NIH Roadmap for Biomedical Research, the NIH Human Microbiome Project was originally established as a 5-y project with a budget of $150 million (335). The project began with a “jumpstart” phase in 2007 and a set of grants was funded in mid-2009 and additional demonstration project grants were awarded. These activities were supported by a Data Analysis and Coordination Center and a set of additional grants was awarded for developing new technologies, new software tools, and studying the ethical, legal, and social implications of this work. The grantees worked together in a highly cooperative consortium. Ultimately, this 10-y $215 million project spanned \u003e20 of the NIH institutes, centers, and offices and resulted in a \u003e40-fold increase in nonproject investment in microbiome research (336). That is, individual or multiple institutes, centers, and offices used program announcements or request for applications. Some of these funding mechanisms were supported by the Common Fund and others were additional commitments by the participating NIH institutes, centers, and offices from their own budgets. The Trans-NIH Microbiome Working Group established in 2012 provided a forum for coordinating NIH extramural research activities related to the human microbiome and continues to coordinate this work after the NIH Human Microbiome Project was completed. Notably, the NIH Human Microbiome Project identified several potential priority areas around food and the microbiome, but these topics have not yet been systematically pursued."}

{"project":"2_test","denotations":[{"id":"32687145-19819907-2017942","span":{"begin":376,"end":379},"obj":"19819907"},{"id":"32687145-30808411-2017943","span":{"begin":1025,"end":1028},"obj":"30808411"}],"text":"As one example, the NIH Human Microbiome Project was a trans-NIH initiative supported by the NIH Common Fund from 2007 to 2016 (334). This project aimed to expand science on the microbiome. Initially funded as an initiative of the NIH Roadmap for Biomedical Research, the NIH Human Microbiome Project was originally established as a 5-y project with a budget of $150 million (335). The project began with a “jumpstart” phase in 2007 and a set of grants was funded in mid-2009 and additional demonstration project grants were awarded. These activities were supported by a Data Analysis and Coordination Center and a set of additional grants was awarded for developing new technologies, new software tools, and studying the ethical, legal, and social implications of this work. The grantees worked together in a highly cooperative consortium. Ultimately, this 10-y $215 million project spanned \u003e20 of the NIH institutes, centers, and offices and resulted in a \u003e40-fold increase in nonproject investment in microbiome research (336). That is, individual or multiple institutes, centers, and offices used program announcements or request for applications. Some of these funding mechanisms were supported by the Common Fund and others were additional commitments by the participating NIH institutes, centers, and offices from their own budgets. The Trans-NIH Microbiome Working Group established in 2012 provided a forum for coordinating NIH extramural research activities related to the human microbiome and continues to coordinate this work after the NIH Human Microbiome Project was completed. Notably, the NIH Human Microbiome Project identified several potential priority areas around food and the microbiome, but these topics have not yet been systematically pursued."}