PMC:7454258 / 106673-108498 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T41551","span":{"begin":1421,"end":1432},"obj":"Body_part"},{"id":"T93576","span":{"begin":1650,"end":1655},"obj":"Body_part"}],"attributes":[{"id":"A76916","pred":"fma_id","subj":"T41551","obj":"http://purl.org/sig/ont/fma/fma293882"},{"id":"A84208","pred":"fma_id","subj":"T93576","obj":"http://purl.org/sig/ont/fma/fma82737"}],"text":"Nutrition research is foundational for diverse federal, tribal, state, and local food and nutrition regulatory activities including labeling, health claims, food marketing, and oversight of food additives and other constituents (204). For example, Congress in 1990 (Public Law 101–535) authorized the Secretary of HHS to provide consumers with accurate nutrition information on food labels, giving rise to the Nutrition Facts panel. In 1994, the GAO recommended that USDA and FDA work together to perform laboratory analyses to independently verify the accuracy of nutrition labels; review labels for compliance with formatting requirements, nutrient content claims, and health claims; work with companies to correct identified inaccuracies; and where appropriate, pursue legal action against products with inappropriate labels (205). Since that time, USDA and FDA, among other federal departments and agencies, have needed to work together on these topics. Examples include the determination that partially hydrogenated oils (high in industrial trans fat) were no longer Generally Recognized As Safe (GRAS), for which NIH- and USDA-funded research, CDC surveillance data, and HHS regulatory reviews supported the FDA determination (206); and FDA's amendment of the food additive regulations to change the standard of identity of enriched flour and corn masa flour (207) to allow folic acid fortification to help prevent neural tube defects in developing infants, which required similar inputs from diverse federal research, surveillance, and regulatory efforts. Another example is the 2016 Nutrition Facts updates (e.g., requiring labeling of added sugar) based on new scientific research, updated DGAs, consensus reports, and national survey data, along with input obtained through proposed rulemaking processes (208, 209)."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T40","span":{"begin":1421,"end":1432},"obj":"Body_part"},{"id":"T41","span":{"begin":1428,"end":1432},"obj":"Body_part"}],"attributes":[{"id":"A40","pred":"uberon_id","subj":"T40","obj":"http://purl.obolibrary.org/obo/UBERON_0001049"},{"id":"A41","pred":"uberon_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/UBERON_0000025"}],"text":"Nutrition research is foundational for diverse federal, tribal, state, and local food and nutrition regulatory activities including labeling, health claims, food marketing, and oversight of food additives and other constituents (204). For example, Congress in 1990 (Public Law 101–535) authorized the Secretary of HHS to provide consumers with accurate nutrition information on food labels, giving rise to the Nutrition Facts panel. In 1994, the GAO recommended that USDA and FDA work together to perform laboratory analyses to independently verify the accuracy of nutrition labels; review labels for compliance with formatting requirements, nutrient content claims, and health claims; work with companies to correct identified inaccuracies; and where appropriate, pursue legal action against products with inappropriate labels (205). Since that time, USDA and FDA, among other federal departments and agencies, have needed to work together on these topics. Examples include the determination that partially hydrogenated oils (high in industrial trans fat) were no longer Generally Recognized As Safe (GRAS), for which NIH- and USDA-funded research, CDC surveillance data, and HHS regulatory reviews supported the FDA determination (206); and FDA's amendment of the food additive regulations to change the standard of identity of enriched flour and corn masa flour (207) to allow folic acid fortification to help prevent neural tube defects in developing infants, which required similar inputs from diverse federal research, surveillance, and regulatory efforts. Another example is the 2016 Nutrition Facts updates (e.g., requiring labeling of added sugar) based on new scientific research, updated DGAs, consensus reports, and national survey data, along with input obtained through proposed rulemaking processes (208, 209)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T204","span":{"begin":314,"end":317},"obj":"Disease"},{"id":"T206","span":{"begin":1177,"end":1180},"obj":"Disease"},{"id":"T208","span":{"begin":1421,"end":1440},"obj":"Disease"}],"attributes":[{"id":"A204","pred":"mondo_id","subj":"T204","obj":"http://purl.obolibrary.org/obo/MONDO_0008897"},{"id":"A205","pred":"mondo_id","subj":"T204","obj":"http://purl.obolibrary.org/obo/MONDO_0011549"},{"id":"A206","pred":"mondo_id","subj":"T206","obj":"http://purl.obolibrary.org/obo/MONDO_0008897"},{"id":"A207","pred":"mondo_id","subj":"T206","obj":"http://purl.obolibrary.org/obo/MONDO_0011549"},{"id":"A208","pred":"mondo_id","subj":"T208","obj":"http://purl.obolibrary.org/obo/MONDO_0018075"}],"text":"Nutrition research is foundational for diverse federal, tribal, state, and local food and nutrition regulatory activities including labeling, health claims, food marketing, and oversight of food additives and other constituents (204). For example, Congress in 1990 (Public Law 101–535) authorized the Secretary of HHS to provide consumers with accurate nutrition information on food labels, giving rise to the Nutrition Facts panel. In 1994, the GAO recommended that USDA and FDA work together to perform laboratory analyses to independently verify the accuracy of nutrition labels; review labels for compliance with formatting requirements, nutrient content claims, and health claims; work with companies to correct identified inaccuracies; and where appropriate, pursue legal action against products with inappropriate labels (205). Since that time, USDA and FDA, among other federal departments and agencies, have needed to work together on these topics. Examples include the determination that partially hydrogenated oils (high in industrial trans fat) were no longer Generally Recognized As Safe (GRAS), for which NIH- and USDA-funded research, CDC surveillance data, and HHS regulatory reviews supported the FDA determination (206); and FDA's amendment of the food additive regulations to change the standard of identity of enriched flour and corn masa flour (207) to allow folic acid fortification to help prevent neural tube defects in developing infants, which required similar inputs from diverse federal research, surveillance, and regulatory efforts. Another example is the 2016 Nutrition Facts updates (e.g., requiring labeling of added sugar) based on new scientific research, updated DGAs, consensus reports, and national survey data, along with input obtained through proposed rulemaking processes (208, 209)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T84697","span":{"begin":111,"end":121},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T25335","span":{"begin":132,"end":140},"obj":"http://purl.obolibrary.org/obo/CLO_0007225"},{"id":"T65926","span":{"begin":383,"end":389},"obj":"http://purl.obolibrary.org/obo/CLO_0007225"},{"id":"T83557","span":{"begin":575,"end":581},"obj":"http://purl.obolibrary.org/obo/CLO_0007225"},{"id":"T69569","span":{"begin":590,"end":596},"obj":"http://purl.obolibrary.org/obo/CLO_0007225"},{"id":"T75149","span":{"begin":821,"end":827},"obj":"http://purl.obolibrary.org/obo/CLO_0007225"},{"id":"T64554","span":{"begin":1052,"end":1055},"obj":"http://purl.obolibrary.org/obo/UBERON_0001013"},{"id":"T78831","span":{"begin":1150,"end":1153},"obj":"http://purl.obolibrary.org/obo/CL_0000990"},{"id":"T97140","span":{"begin":1428,"end":1432},"obj":"http://purl.obolibrary.org/obo/UBERON_0000025"},{"id":"T44251","span":{"begin":1632,"end":1640},"obj":"http://purl.obolibrary.org/obo/CLO_0007225"}],"text":"Nutrition research is foundational for diverse federal, tribal, state, and local food and nutrition regulatory activities including labeling, health claims, food marketing, and oversight of food additives and other constituents (204). For example, Congress in 1990 (Public Law 101–535) authorized the Secretary of HHS to provide consumers with accurate nutrition information on food labels, giving rise to the Nutrition Facts panel. In 1994, the GAO recommended that USDA and FDA work together to perform laboratory analyses to independently verify the accuracy of nutrition labels; review labels for compliance with formatting requirements, nutrient content claims, and health claims; work with companies to correct identified inaccuracies; and where appropriate, pursue legal action against products with inappropriate labels (205). Since that time, USDA and FDA, among other federal departments and agencies, have needed to work together on these topics. Examples include the determination that partially hydrogenated oils (high in industrial trans fat) were no longer Generally Recognized As Safe (GRAS), for which NIH- and USDA-funded research, CDC surveillance data, and HHS regulatory reviews supported the FDA determination (206); and FDA's amendment of the food additive regulations to change the standard of identity of enriched flour and corn masa flour (207) to allow folic acid fortification to help prevent neural tube defects in developing infants, which required similar inputs from diverse federal research, surveillance, and regulatory efforts. Another example is the 2016 Nutrition Facts updates (e.g., requiring labeling of added sugar) based on new scientific research, updated DGAs, consensus reports, and national survey data, along with input obtained through proposed rulemaking processes (208, 209)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T37641","span":{"begin":190,"end":204},"obj":"Chemical"},{"id":"T87328","span":{"begin":314,"end":317},"obj":"Chemical"},{"id":"T36339","span":{"begin":642,"end":650},"obj":"Chemical"},{"id":"T60922","span":{"begin":1177,"end":1180},"obj":"Chemical"},{"id":"T9590","span":{"begin":1266,"end":1279},"obj":"Chemical"},{"id":"T82828","span":{"begin":1380,"end":1390},"obj":"Chemical"},{"id":"T88892","span":{"begin":1386,"end":1390},"obj":"Chemical"}],"attributes":[{"id":"A78375","pred":"chebi_id","subj":"T37641","obj":"http://purl.obolibrary.org/obo/CHEBI_64047"},{"id":"A44920","pred":"chebi_id","subj":"T87328","obj":"http://purl.obolibrary.org/obo/CHEBI_88937"},{"id":"A26009","pred":"chebi_id","subj":"T36339","obj":"http://purl.obolibrary.org/obo/CHEBI_33284"},{"id":"A92788","pred":"chebi_id","subj":"T60922","obj":"http://purl.obolibrary.org/obo/CHEBI_88937"},{"id":"A62963","pred":"chebi_id","subj":"T9590","obj":"http://purl.obolibrary.org/obo/CHEBI_64047"},{"id":"A59161","pred":"chebi_id","subj":"T82828","obj":"http://purl.obolibrary.org/obo/CHEBI_27470"},{"id":"A22602","pred":"chebi_id","subj":"T88892","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"}],"text":"Nutrition research is foundational for diverse federal, tribal, state, and local food and nutrition regulatory activities including labeling, health claims, food marketing, and oversight of food additives and other constituents (204). For example, Congress in 1990 (Public Law 101–535) authorized the Secretary of HHS to provide consumers with accurate nutrition information on food labels, giving rise to the Nutrition Facts panel. In 1994, the GAO recommended that USDA and FDA work together to perform laboratory analyses to independently verify the accuracy of nutrition labels; review labels for compliance with formatting requirements, nutrient content claims, and health claims; work with companies to correct identified inaccuracies; and where appropriate, pursue legal action against products with inappropriate labels (205). Since that time, USDA and FDA, among other federal departments and agencies, have needed to work together on these topics. Examples include the determination that partially hydrogenated oils (high in industrial trans fat) were no longer Generally Recognized As Safe (GRAS), for which NIH- and USDA-funded research, CDC surveillance data, and HHS regulatory reviews supported the FDA determination (206); and FDA's amendment of the food additive regulations to change the standard of identity of enriched flour and corn masa flour (207) to allow folic acid fortification to help prevent neural tube defects in developing infants, which required similar inputs from diverse federal research, surveillance, and regulatory efforts. Another example is the 2016 Nutrition Facts updates (e.g., requiring labeling of added sugar) based on new scientific research, updated DGAs, consensus reports, and national survey data, along with input obtained through proposed rulemaking processes (208, 209)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T29074","span":{"begin":1280,"end":1291},"obj":"http://purl.obolibrary.org/obo/GO_0065007"}],"text":"Nutrition research is foundational for diverse federal, tribal, state, and local food and nutrition regulatory activities including labeling, health claims, food marketing, and oversight of food additives and other constituents (204). For example, Congress in 1990 (Public Law 101–535) authorized the Secretary of HHS to provide consumers with accurate nutrition information on food labels, giving rise to the Nutrition Facts panel. In 1994, the GAO recommended that USDA and FDA work together to perform laboratory analyses to independently verify the accuracy of nutrition labels; review labels for compliance with formatting requirements, nutrient content claims, and health claims; work with companies to correct identified inaccuracies; and where appropriate, pursue legal action against products with inappropriate labels (205). Since that time, USDA and FDA, among other federal departments and agencies, have needed to work together on these topics. Examples include the determination that partially hydrogenated oils (high in industrial trans fat) were no longer Generally Recognized As Safe (GRAS), for which NIH- and USDA-funded research, CDC surveillance data, and HHS regulatory reviews supported the FDA determination (206); and FDA's amendment of the food additive regulations to change the standard of identity of enriched flour and corn masa flour (207) to allow folic acid fortification to help prevent neural tube defects in developing infants, which required similar inputs from diverse federal research, surveillance, and regulatory efforts. Another example is the 2016 Nutrition Facts updates (e.g., requiring labeling of added sugar) based on new scientific research, updated DGAs, consensus reports, and national survey data, along with input obtained through proposed rulemaking processes (208, 209)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"576","span":{"begin":1455,"end":1462},"obj":"Species"},{"id":"577","span":{"begin":1380,"end":1390},"obj":"Chemical"},{"id":"578","span":{"begin":1650,"end":1655},"obj":"Chemical"},{"id":"579","span":{"begin":1421,"end":1440},"obj":"Disease"}],"attributes":[{"id":"A576","pred":"tao:has_database_id","subj":"576","obj":"Tax:9606"},{"id":"A577","pred":"tao:has_database_id","subj":"577","obj":"MESH:D005492"},{"id":"A578","pred":"tao:has_database_id","subj":"578","obj":"MESH:D000073893"},{"id":"A579","pred":"tao:has_database_id","subj":"579","obj":"MESH:D005184"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Nutrition research is foundational for diverse federal, tribal, state, and local food and nutrition regulatory activities including labeling, health claims, food marketing, and oversight of food additives and other constituents (204). For example, Congress in 1990 (Public Law 101–535) authorized the Secretary of HHS to provide consumers with accurate nutrition information on food labels, giving rise to the Nutrition Facts panel. In 1994, the GAO recommended that USDA and FDA work together to perform laboratory analyses to independently verify the accuracy of nutrition labels; review labels for compliance with formatting requirements, nutrient content claims, and health claims; work with companies to correct identified inaccuracies; and where appropriate, pursue legal action against products with inappropriate labels (205). Since that time, USDA and FDA, among other federal departments and agencies, have needed to work together on these topics. Examples include the determination that partially hydrogenated oils (high in industrial trans fat) were no longer Generally Recognized As Safe (GRAS), for which NIH- and USDA-funded research, CDC surveillance data, and HHS regulatory reviews supported the FDA determination (206); and FDA's amendment of the food additive regulations to change the standard of identity of enriched flour and corn masa flour (207) to allow folic acid fortification to help prevent neural tube defects in developing infants, which required similar inputs from diverse federal research, surveillance, and regulatory efforts. Another example is the 2016 Nutrition Facts updates (e.g., requiring labeling of added sugar) based on new scientific research, updated DGAs, consensus reports, and national survey data, along with input obtained through proposed rulemaking processes (208, 209)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T561","span":{"begin":0,"end":234},"obj":"Sentence"},{"id":"T562","span":{"begin":235,"end":432},"obj":"Sentence"},{"id":"T563","span":{"begin":433,"end":834},"obj":"Sentence"},{"id":"T564","span":{"begin":835,"end":957},"obj":"Sentence"},{"id":"T565","span":{"begin":958,"end":1562},"obj":"Sentence"},{"id":"T566","span":{"begin":1563,"end":1825},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Nutrition research is foundational for diverse federal, tribal, state, and local food and nutrition regulatory activities including labeling, health claims, food marketing, and oversight of food additives and other constituents (204). For example, Congress in 1990 (Public Law 101–535) authorized the Secretary of HHS to provide consumers with accurate nutrition information on food labels, giving rise to the Nutrition Facts panel. In 1994, the GAO recommended that USDA and FDA work together to perform laboratory analyses to independently verify the accuracy of nutrition labels; review labels for compliance with formatting requirements, nutrient content claims, and health claims; work with companies to correct identified inaccuracies; and where appropriate, pursue legal action against products with inappropriate labels (205). Since that time, USDA and FDA, among other federal departments and agencies, have needed to work together on these topics. Examples include the determination that partially hydrogenated oils (high in industrial trans fat) were no longer Generally Recognized As Safe (GRAS), for which NIH- and USDA-funded research, CDC surveillance data, and HHS regulatory reviews supported the FDA determination (206); and FDA's amendment of the food additive regulations to change the standard of identity of enriched flour and corn masa flour (207) to allow folic acid fortification to help prevent neural tube defects in developing infants, which required similar inputs from diverse federal research, surveillance, and regulatory efforts. Another example is the 2016 Nutrition Facts updates (e.g., requiring labeling of added sugar) based on new scientific research, updated DGAs, consensus reports, and national survey data, along with input obtained through proposed rulemaking processes (208, 209)."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T94","span":{"begin":1421,"end":1440},"obj":"Phenotype"}],"attributes":[{"id":"A94","pred":"hp_id","subj":"T94","obj":"http://purl.obolibrary.org/obo/HP_0045005"}],"text":"Nutrition research is foundational for diverse federal, tribal, state, and local food and nutrition regulatory activities including labeling, health claims, food marketing, and oversight of food additives and other constituents (204). For example, Congress in 1990 (Public Law 101–535) authorized the Secretary of HHS to provide consumers with accurate nutrition information on food labels, giving rise to the Nutrition Facts panel. In 1994, the GAO recommended that USDA and FDA work together to perform laboratory analyses to independently verify the accuracy of nutrition labels; review labels for compliance with formatting requirements, nutrient content claims, and health claims; work with companies to correct identified inaccuracies; and where appropriate, pursue legal action against products with inappropriate labels (205). Since that time, USDA and FDA, among other federal departments and agencies, have needed to work together on these topics. Examples include the determination that partially hydrogenated oils (high in industrial trans fat) were no longer Generally Recognized As Safe (GRAS), for which NIH- and USDA-funded research, CDC surveillance data, and HHS regulatory reviews supported the FDA determination (206); and FDA's amendment of the food additive regulations to change the standard of identity of enriched flour and corn masa flour (207) to allow folic acid fortification to help prevent neural tube defects in developing infants, which required similar inputs from diverse federal research, surveillance, and regulatory efforts. Another example is the 2016 Nutrition Facts updates (e.g., requiring labeling of added sugar) based on new scientific research, updated DGAs, consensus reports, and national survey data, along with input obtained through proposed rulemaking processes (208, 209)."}

{"project":"2_test","denotations":[{"id":"32687145-30982338-2017903","span":{"begin":1820,"end":1823},"obj":"30982338"}],"text":"Nutrition research is foundational for diverse federal, tribal, state, and local food and nutrition regulatory activities including labeling, health claims, food marketing, and oversight of food additives and other constituents (204). For example, Congress in 1990 (Public Law 101–535) authorized the Secretary of HHS to provide consumers with accurate nutrition information on food labels, giving rise to the Nutrition Facts panel. In 1994, the GAO recommended that USDA and FDA work together to perform laboratory analyses to independently verify the accuracy of nutrition labels; review labels for compliance with formatting requirements, nutrient content claims, and health claims; work with companies to correct identified inaccuracies; and where appropriate, pursue legal action against products with inappropriate labels (205). Since that time, USDA and FDA, among other federal departments and agencies, have needed to work together on these topics. Examples include the determination that partially hydrogenated oils (high in industrial trans fat) were no longer Generally Recognized As Safe (GRAS), for which NIH- and USDA-funded research, CDC surveillance data, and HHS regulatory reviews supported the FDA determination (206); and FDA's amendment of the food additive regulations to change the standard of identity of enriched flour and corn masa flour (207) to allow folic acid fortification to help prevent neural tube defects in developing infants, which required similar inputs from diverse federal research, surveillance, and regulatory efforts. Another example is the 2016 Nutrition Facts updates (e.g., requiring labeling of added sugar) based on new scientific research, updated DGAs, consensus reports, and national survey data, along with input obtained through proposed rulemaking processes (208, 209)."}