PMC:7454258 / 101674-104086 JSONTXT

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    LitCovid-PD-FMA-UBERON

    {"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T81564","span":{"begin":322,"end":327},"obj":"Body_part"},{"id":"T51004","span":{"begin":328,"end":335},"obj":"Body_part"},{"id":"T15201","span":{"begin":350,"end":355},"obj":"Body_part"},{"id":"T9581","span":{"begin":370,"end":375},"obj":"Body_part"},{"id":"T10333","span":{"begin":661,"end":666},"obj":"Body_part"},{"id":"T45281","span":{"begin":686,"end":691},"obj":"Body_part"}],"attributes":[{"id":"A31982","pred":"fma_id","subj":"T81564","obj":"http://purl.org/sig/ont/fma/fma9670"},{"id":"A32208","pred":"fma_id","subj":"T51004","obj":"http://purl.org/sig/ont/fma/fma82743"},{"id":"A15849","pred":"fma_id","subj":"T15201","obj":"http://purl.org/sig/ont/fma/fma9670"},{"id":"A62259","pred":"fma_id","subj":"T9581","obj":"http://purl.org/sig/ont/fma/fma228775"},{"id":"A78521","pred":"fma_id","subj":"T10333","obj":"http://purl.org/sig/ont/fma/fma9670"},{"id":"A42643","pred":"fma_id","subj":"T45281","obj":"http://purl.org/sig/ont/fma/fma9670"}],"text":"In 1990, Congress specified that the DGAs focus on the general public, not on specific nutritional recommendations for individuals suffering from diet-related conditions (Public Law 101–445). However, highlighting the scale and scope of diet-related illness, only 12% of US adults are metabolically healthy (as defined by blood glucose, cholesterol, blood pressure, and waist circumference). Thus, the DGAs’ general focus may exclude the specific dietary needs of the great majority of the US population. Until 2014, the NIH supported the development of evidence reviews and dietary guidance for patients with health issues such as overweight and obesity, high blood pressure, and high blood cholesterol, among others (188, 189). These reviews were used by DGACs with input and endorsement from \u003e25 professional groups. The NIH ceased these reports in 2014, in part because the CDC's mandate deals with disease prevention activities and the mandate of the HHS Agency for Healthcare Research and Quality (AHRQ) includes development of systematic evidence reviews to inform clinical practice guidelines (189–191). Certain nongovernmental professional and clinical organizations provide nutrition guidance for populations with or at risk for various chronic conditions, but these various recommendations are not coordinated (192, 193). The current 2020 DGAC process excludes—for the first time—the use of existing high-quality nongovernmental systematic reviews and meta-analyses conducted by peer-reviewed researchers and major professional organizations. Little work has been done to understand the short- or long-term implications of NIH's shift in 2014 away from dietary guidance for populations with disease conditions, or whether CDC and AHRQ efforts are addressing this gap. Thus, currently no federal entity takes the lead on the development of evidence reviews or dietary guidance for patients with diet-related health conditions. Several organizations, including AND, the National Association for the Advancement of Colored People, and the National Hispanic Medical Association, recently formed the Food4Health Alliance to advocate for additional federal nutrition guidelines tailored to the needs of tens of millions of Americans who have diet-related diseases such as hypertension, obesity, and type 2 diabetes—conditions that also disproportionately affect minorities and underserved communities (194)."}

    LitCovid-PD-UBERON

    {"project":"LitCovid-PD-UBERON","denotations":[{"id":"T35","span":{"begin":218,"end":223},"obj":"Body_part"},{"id":"T36","span":{"begin":322,"end":327},"obj":"Body_part"},{"id":"T37","span":{"begin":350,"end":355},"obj":"Body_part"},{"id":"T38","span":{"begin":661,"end":666},"obj":"Body_part"},{"id":"T39","span":{"begin":686,"end":691},"obj":"Body_part"}],"attributes":[{"id":"A35","pred":"uberon_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/UBERON_0002542"},{"id":"A36","pred":"uberon_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A37","pred":"uberon_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A38","pred":"uberon_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A39","pred":"uberon_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"}],"text":"In 1990, Congress specified that the DGAs focus on the general public, not on specific nutritional recommendations for individuals suffering from diet-related conditions (Public Law 101–445). However, highlighting the scale and scope of diet-related illness, only 12% of US adults are metabolically healthy (as defined by blood glucose, cholesterol, blood pressure, and waist circumference). Thus, the DGAs’ general focus may exclude the specific dietary needs of the great majority of the US population. Until 2014, the NIH supported the development of evidence reviews and dietary guidance for patients with health issues such as overweight and obesity, high blood pressure, and high blood cholesterol, among others (188, 189). These reviews were used by DGACs with input and endorsement from \u003e25 professional groups. The NIH ceased these reports in 2014, in part because the CDC's mandate deals with disease prevention activities and the mandate of the HHS Agency for Healthcare Research and Quality (AHRQ) includes development of systematic evidence reviews to inform clinical practice guidelines (189–191). Certain nongovernmental professional and clinical organizations provide nutrition guidance for populations with or at risk for various chronic conditions, but these various recommendations are not coordinated (192, 193). The current 2020 DGAC process excludes—for the first time—the use of existing high-quality nongovernmental systematic reviews and meta-analyses conducted by peer-reviewed researchers and major professional organizations. Little work has been done to understand the short- or long-term implications of NIH's shift in 2014 away from dietary guidance for populations with disease conditions, or whether CDC and AHRQ efforts are addressing this gap. Thus, currently no federal entity takes the lead on the development of evidence reviews or dietary guidance for patients with diet-related health conditions. Several organizations, including AND, the National Association for the Advancement of Colored People, and the National Hispanic Medical Association, recently formed the Food4Health Alliance to advocate for additional federal nutrition guidelines tailored to the needs of tens of millions of Americans who have diet-related diseases such as hypertension, obesity, and type 2 diabetes—conditions that also disproportionately affect minorities and underserved communities (194)."}

    LitCovid-PD-MONDO

    {"project":"LitCovid-PD-MONDO","denotations":[{"id":"T195","span":{"begin":647,"end":654},"obj":"Disease"},{"id":"T196","span":{"begin":656,"end":675},"obj":"Disease"},{"id":"T197","span":{"begin":956,"end":959},"obj":"Disease"},{"id":"T199","span":{"begin":2277,"end":2289},"obj":"Disease"},{"id":"T200","span":{"begin":2291,"end":2298},"obj":"Disease"},{"id":"T201","span":{"begin":2304,"end":2319},"obj":"Disease"},{"id":"T202","span":{"begin":2311,"end":2319},"obj":"Disease"}],"attributes":[{"id":"A195","pred":"mondo_id","subj":"T195","obj":"http://purl.obolibrary.org/obo/MONDO_0011122"},{"id":"A196","pred":"mondo_id","subj":"T196","obj":"http://purl.obolibrary.org/obo/MONDO_0005044"},{"id":"A197","pred":"mondo_id","subj":"T197","obj":"http://purl.obolibrary.org/obo/MONDO_0008897"},{"id":"A198","pred":"mondo_id","subj":"T197","obj":"http://purl.obolibrary.org/obo/MONDO_0011549"},{"id":"A199","pred":"mondo_id","subj":"T199","obj":"http://purl.obolibrary.org/obo/MONDO_0005044"},{"id":"A200","pred":"mondo_id","subj":"T200","obj":"http://purl.obolibrary.org/obo/MONDO_0011122"},{"id":"A201","pred":"mondo_id","subj":"T201","obj":"http://purl.obolibrary.org/obo/MONDO_0005148"},{"id":"A202","pred":"mondo_id","subj":"T202","obj":"http://purl.obolibrary.org/obo/MONDO_0005015"}],"text":"In 1990, Congress specified that the DGAs focus on the general public, not on specific nutritional recommendations for individuals suffering from diet-related conditions (Public Law 101–445). However, highlighting the scale and scope of diet-related illness, only 12% of US adults are metabolically healthy (as defined by blood glucose, cholesterol, blood pressure, and waist circumference). Thus, the DGAs’ general focus may exclude the specific dietary needs of the great majority of the US population. Until 2014, the NIH supported the development of evidence reviews and dietary guidance for patients with health issues such as overweight and obesity, high blood pressure, and high blood cholesterol, among others (188, 189). These reviews were used by DGACs with input and endorsement from \u003e25 professional groups. The NIH ceased these reports in 2014, in part because the CDC's mandate deals with disease prevention activities and the mandate of the HHS Agency for Healthcare Research and Quality (AHRQ) includes development of systematic evidence reviews to inform clinical practice guidelines (189–191). Certain nongovernmental professional and clinical organizations provide nutrition guidance for populations with or at risk for various chronic conditions, but these various recommendations are not coordinated (192, 193). The current 2020 DGAC process excludes—for the first time—the use of existing high-quality nongovernmental systematic reviews and meta-analyses conducted by peer-reviewed researchers and major professional organizations. Little work has been done to understand the short- or long-term implications of NIH's shift in 2014 away from dietary guidance for populations with disease conditions, or whether CDC and AHRQ efforts are addressing this gap. Thus, currently no federal entity takes the lead on the development of evidence reviews or dietary guidance for patients with diet-related health conditions. Several organizations, including AND, the National Association for the Advancement of Colored People, and the National Hispanic Medical Association, recently formed the Food4Health Alliance to advocate for additional federal nutrition guidelines tailored to the needs of tens of millions of Americans who have diet-related diseases such as hypertension, obesity, and type 2 diabetes—conditions that also disproportionately affect minorities and underserved communities (194)."}

    LitCovid-PD-CLO

    {"project":"LitCovid-PD-CLO","denotations":[{"id":"T20172","span":{"begin":42,"end":47},"obj":"http://purl.obolibrary.org/obo/CLO_0009985"},{"id":"T30730","span":{"begin":322,"end":327},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T88373","span":{"begin":322,"end":327},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T77388","span":{"begin":350,"end":355},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T93943","span":{"begin":350,"end":355},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T9287","span":{"begin":416,"end":421},"obj":"http://purl.obolibrary.org/obo/CLO_0009985"},{"id":"T59944","span":{"begin":661,"end":666},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T42369","span":{"begin":661,"end":666},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T16018","span":{"begin":686,"end":691},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T75644","span":{"begin":686,"end":691},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T99223","span":{"begin":922,"end":932},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T3127","span":{"begin":1162,"end":1175},"obj":"http://purl.obolibrary.org/obo/OBI_0000245"},{"id":"T45829","span":{"begin":1490,"end":1494},"obj":"http://purl.obolibrary.org/obo/CLO_0008416"},{"id":"T82149","span":{"begin":1490,"end":1494},"obj":"http://purl.obolibrary.org/obo/CLO_0050081"},{"id":"T53952","span":{"begin":1539,"end":1552},"obj":"http://purl.obolibrary.org/obo/OBI_0000245"},{"id":"T16870","span":{"begin":1566,"end":1569},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T30298","span":{"begin":1733,"end":1736},"obj":"http://purl.obolibrary.org/obo/CL_0000990"},{"id":"T45347","span":{"begin":1945,"end":1958},"obj":"http://purl.obolibrary.org/obo/OBI_0000245"}],"text":"In 1990, Congress specified that the DGAs focus on the general public, not on specific nutritional recommendations for individuals suffering from diet-related conditions (Public Law 101–445). However, highlighting the scale and scope of diet-related illness, only 12% of US adults are metabolically healthy (as defined by blood glucose, cholesterol, blood pressure, and waist circumference). Thus, the DGAs’ general focus may exclude the specific dietary needs of the great majority of the US population. Until 2014, the NIH supported the development of evidence reviews and dietary guidance for patients with health issues such as overweight and obesity, high blood pressure, and high blood cholesterol, among others (188, 189). These reviews were used by DGACs with input and endorsement from \u003e25 professional groups. The NIH ceased these reports in 2014, in part because the CDC's mandate deals with disease prevention activities and the mandate of the HHS Agency for Healthcare Research and Quality (AHRQ) includes development of systematic evidence reviews to inform clinical practice guidelines (189–191). Certain nongovernmental professional and clinical organizations provide nutrition guidance for populations with or at risk for various chronic conditions, but these various recommendations are not coordinated (192, 193). The current 2020 DGAC process excludes—for the first time—the use of existing high-quality nongovernmental systematic reviews and meta-analyses conducted by peer-reviewed researchers and major professional organizations. Little work has been done to understand the short- or long-term implications of NIH's shift in 2014 away from dietary guidance for populations with disease conditions, or whether CDC and AHRQ efforts are addressing this gap. Thus, currently no federal entity takes the lead on the development of evidence reviews or dietary guidance for patients with diet-related health conditions. Several organizations, including AND, the National Association for the Advancement of Colored People, and the National Hispanic Medical Association, recently formed the Food4Health Alliance to advocate for additional federal nutrition guidelines tailored to the needs of tens of millions of Americans who have diet-related diseases such as hypertension, obesity, and type 2 diabetes—conditions that also disproportionately affect minorities and underserved communities (194)."}

    LitCovid-PD-CHEBI

    {"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T44573","span":{"begin":328,"end":335},"obj":"Chemical"},{"id":"T97910","span":{"begin":337,"end":348},"obj":"Chemical"},{"id":"T45598","span":{"begin":692,"end":703},"obj":"Chemical"},{"id":"T67279","span":{"begin":956,"end":959},"obj":"Chemical"}],"attributes":[{"id":"A61126","pred":"chebi_id","subj":"T44573","obj":"http://purl.obolibrary.org/obo/CHEBI_17234"},{"id":"A97541","pred":"chebi_id","subj":"T44573","obj":"http://purl.obolibrary.org/obo/CHEBI_4167"},{"id":"A98542","pred":"chebi_id","subj":"T97910","obj":"http://purl.obolibrary.org/obo/CHEBI_16113"},{"id":"A8207","pred":"chebi_id","subj":"T45598","obj":"http://purl.obolibrary.org/obo/CHEBI_16113"},{"id":"A92958","pred":"chebi_id","subj":"T67279","obj":"http://purl.obolibrary.org/obo/CHEBI_88937"}],"text":"In 1990, Congress specified that the DGAs focus on the general public, not on specific nutritional recommendations for individuals suffering from diet-related conditions (Public Law 101–445). However, highlighting the scale and scope of diet-related illness, only 12% of US adults are metabolically healthy (as defined by blood glucose, cholesterol, blood pressure, and waist circumference). Thus, the DGAs’ general focus may exclude the specific dietary needs of the great majority of the US population. Until 2014, the NIH supported the development of evidence reviews and dietary guidance for patients with health issues such as overweight and obesity, high blood pressure, and high blood cholesterol, among others (188, 189). These reviews were used by DGACs with input and endorsement from \u003e25 professional groups. The NIH ceased these reports in 2014, in part because the CDC's mandate deals with disease prevention activities and the mandate of the HHS Agency for Healthcare Research and Quality (AHRQ) includes development of systematic evidence reviews to inform clinical practice guidelines (189–191). Certain nongovernmental professional and clinical organizations provide nutrition guidance for populations with or at risk for various chronic conditions, but these various recommendations are not coordinated (192, 193). The current 2020 DGAC process excludes—for the first time—the use of existing high-quality nongovernmental systematic reviews and meta-analyses conducted by peer-reviewed researchers and major professional organizations. Little work has been done to understand the short- or long-term implications of NIH's shift in 2014 away from dietary guidance for populations with disease conditions, or whether CDC and AHRQ efforts are addressing this gap. Thus, currently no federal entity takes the lead on the development of evidence reviews or dietary guidance for patients with diet-related health conditions. Several organizations, including AND, the National Association for the Advancement of Colored People, and the National Hispanic Medical Association, recently formed the Food4Health Alliance to advocate for additional federal nutrition guidelines tailored to the needs of tens of millions of Americans who have diet-related diseases such as hypertension, obesity, and type 2 diabetes—conditions that also disproportionately affect minorities and underserved communities (194)."}

    LitCovid-PubTator

    {"project":"LitCovid-PubTator","denotations":[{"id":"556","span":{"begin":596,"end":604},"obj":"Species"},{"id":"557","span":{"begin":1891,"end":1899},"obj":"Species"},{"id":"558","span":{"begin":2031,"end":2037},"obj":"Species"},{"id":"559","span":{"begin":328,"end":335},"obj":"Chemical"},{"id":"560","span":{"begin":337,"end":348},"obj":"Chemical"},{"id":"561","span":{"begin":692,"end":703},"obj":"Chemical"},{"id":"562","span":{"begin":647,"end":654},"obj":"Disease"},{"id":"563","span":{"begin":2277,"end":2289},"obj":"Disease"},{"id":"564","span":{"begin":2291,"end":2298},"obj":"Disease"},{"id":"565","span":{"begin":2304,"end":2319},"obj":"Disease"}],"attributes":[{"id":"A556","pred":"tao:has_database_id","subj":"556","obj":"Tax:9606"},{"id":"A557","pred":"tao:has_database_id","subj":"557","obj":"Tax:9606"},{"id":"A558","pred":"tao:has_database_id","subj":"558","obj":"Tax:9606"},{"id":"A559","pred":"tao:has_database_id","subj":"559","obj":"MESH:D005947"},{"id":"A560","pred":"tao:has_database_id","subj":"560","obj":"MESH:D002784"},{"id":"A561","pred":"tao:has_database_id","subj":"561","obj":"MESH:D002784"},{"id":"A562","pred":"tao:has_database_id","subj":"562","obj":"MESH:D009765"},{"id":"A563","pred":"tao:has_database_id","subj":"563","obj":"MESH:D006973"},{"id":"A564","pred":"tao:has_database_id","subj":"564","obj":"MESH:D009765"},{"id":"A565","pred":"tao:has_database_id","subj":"565","obj":"MESH:D003924"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In 1990, Congress specified that the DGAs focus on the general public, not on specific nutritional recommendations for individuals suffering from diet-related conditions (Public Law 101–445). However, highlighting the scale and scope of diet-related illness, only 12% of US adults are metabolically healthy (as defined by blood glucose, cholesterol, blood pressure, and waist circumference). Thus, the DGAs’ general focus may exclude the specific dietary needs of the great majority of the US population. Until 2014, the NIH supported the development of evidence reviews and dietary guidance for patients with health issues such as overweight and obesity, high blood pressure, and high blood cholesterol, among others (188, 189). These reviews were used by DGACs with input and endorsement from \u003e25 professional groups. The NIH ceased these reports in 2014, in part because the CDC's mandate deals with disease prevention activities and the mandate of the HHS Agency for Healthcare Research and Quality (AHRQ) includes development of systematic evidence reviews to inform clinical practice guidelines (189–191). Certain nongovernmental professional and clinical organizations provide nutrition guidance for populations with or at risk for various chronic conditions, but these various recommendations are not coordinated (192, 193). The current 2020 DGAC process excludes—for the first time—the use of existing high-quality nongovernmental systematic reviews and meta-analyses conducted by peer-reviewed researchers and major professional organizations. Little work has been done to understand the short- or long-term implications of NIH's shift in 2014 away from dietary guidance for populations with disease conditions, or whether CDC and AHRQ efforts are addressing this gap. Thus, currently no federal entity takes the lead on the development of evidence reviews or dietary guidance for patients with diet-related health conditions. Several organizations, including AND, the National Association for the Advancement of Colored People, and the National Hispanic Medical Association, recently formed the Food4Health Alliance to advocate for additional federal nutrition guidelines tailored to the needs of tens of millions of Americans who have diet-related diseases such as hypertension, obesity, and type 2 diabetes—conditions that also disproportionately affect minorities and underserved communities (194)."}

    LitCovid-sentences

    {"project":"LitCovid-sentences","denotations":[{"id":"T536","span":{"begin":0,"end":191},"obj":"Sentence"},{"id":"T537","span":{"begin":192,"end":391},"obj":"Sentence"},{"id":"T538","span":{"begin":392,"end":504},"obj":"Sentence"},{"id":"T539","span":{"begin":505,"end":729},"obj":"Sentence"},{"id":"T540","span":{"begin":730,"end":819},"obj":"Sentence"},{"id":"T541","span":{"begin":820,"end":1111},"obj":"Sentence"},{"id":"T542","span":{"begin":1112,"end":1332},"obj":"Sentence"},{"id":"T543","span":{"begin":1333,"end":1553},"obj":"Sentence"},{"id":"T544","span":{"begin":1554,"end":1778},"obj":"Sentence"},{"id":"T545","span":{"begin":1779,"end":1936},"obj":"Sentence"},{"id":"T546","span":{"begin":1937,"end":2412},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In 1990, Congress specified that the DGAs focus on the general public, not on specific nutritional recommendations for individuals suffering from diet-related conditions (Public Law 101–445). However, highlighting the scale and scope of diet-related illness, only 12% of US adults are metabolically healthy (as defined by blood glucose, cholesterol, blood pressure, and waist circumference). Thus, the DGAs’ general focus may exclude the specific dietary needs of the great majority of the US population. Until 2014, the NIH supported the development of evidence reviews and dietary guidance for patients with health issues such as overweight and obesity, high blood pressure, and high blood cholesterol, among others (188, 189). These reviews were used by DGACs with input and endorsement from \u003e25 professional groups. The NIH ceased these reports in 2014, in part because the CDC's mandate deals with disease prevention activities and the mandate of the HHS Agency for Healthcare Research and Quality (AHRQ) includes development of systematic evidence reviews to inform clinical practice guidelines (189–191). Certain nongovernmental professional and clinical organizations provide nutrition guidance for populations with or at risk for various chronic conditions, but these various recommendations are not coordinated (192, 193). The current 2020 DGAC process excludes—for the first time—the use of existing high-quality nongovernmental systematic reviews and meta-analyses conducted by peer-reviewed researchers and major professional organizations. Little work has been done to understand the short- or long-term implications of NIH's shift in 2014 away from dietary guidance for populations with disease conditions, or whether CDC and AHRQ efforts are addressing this gap. Thus, currently no federal entity takes the lead on the development of evidence reviews or dietary guidance for patients with diet-related health conditions. Several organizations, including AND, the National Association for the Advancement of Colored People, and the National Hispanic Medical Association, recently formed the Food4Health Alliance to advocate for additional federal nutrition guidelines tailored to the needs of tens of millions of Americans who have diet-related diseases such as hypertension, obesity, and type 2 diabetes—conditions that also disproportionately affect minorities and underserved communities (194)."}

    LitCovid-PD-HP

    {"project":"LitCovid-PD-HP","denotations":[{"id":"T88","span":{"begin":632,"end":642},"obj":"Phenotype"},{"id":"T89","span":{"begin":647,"end":654},"obj":"Phenotype"},{"id":"T90","span":{"begin":656,"end":675},"obj":"Phenotype"},{"id":"T91","span":{"begin":2277,"end":2289},"obj":"Phenotype"},{"id":"T92","span":{"begin":2291,"end":2298},"obj":"Phenotype"},{"id":"T93","span":{"begin":2304,"end":2319},"obj":"Phenotype"}],"attributes":[{"id":"A88","pred":"hp_id","subj":"T88","obj":"http://purl.obolibrary.org/obo/HP_0025502"},{"id":"A89","pred":"hp_id","subj":"T89","obj":"http://purl.obolibrary.org/obo/HP_0001513"},{"id":"A90","pred":"hp_id","subj":"T90","obj":"http://purl.obolibrary.org/obo/HP_0000822"},{"id":"A91","pred":"hp_id","subj":"T91","obj":"http://purl.obolibrary.org/obo/HP_0000822"},{"id":"A92","pred":"hp_id","subj":"T92","obj":"http://purl.obolibrary.org/obo/HP_0001513"},{"id":"A93","pred":"hp_id","subj":"T93","obj":"http://purl.obolibrary.org/obo/HP_0005978"}],"text":"In 1990, Congress specified that the DGAs focus on the general public, not on specific nutritional recommendations for individuals suffering from diet-related conditions (Public Law 101–445). However, highlighting the scale and scope of diet-related illness, only 12% of US adults are metabolically healthy (as defined by blood glucose, cholesterol, blood pressure, and waist circumference). Thus, the DGAs’ general focus may exclude the specific dietary needs of the great majority of the US population. Until 2014, the NIH supported the development of evidence reviews and dietary guidance for patients with health issues such as overweight and obesity, high blood pressure, and high blood cholesterol, among others (188, 189). These reviews were used by DGACs with input and endorsement from \u003e25 professional groups. The NIH ceased these reports in 2014, in part because the CDC's mandate deals with disease prevention activities and the mandate of the HHS Agency for Healthcare Research and Quality (AHRQ) includes development of systematic evidence reviews to inform clinical practice guidelines (189–191). Certain nongovernmental professional and clinical organizations provide nutrition guidance for populations with or at risk for various chronic conditions, but these various recommendations are not coordinated (192, 193). The current 2020 DGAC process excludes—for the first time—the use of existing high-quality nongovernmental systematic reviews and meta-analyses conducted by peer-reviewed researchers and major professional organizations. Little work has been done to understand the short- or long-term implications of NIH's shift in 2014 away from dietary guidance for populations with disease conditions, or whether CDC and AHRQ efforts are addressing this gap. Thus, currently no federal entity takes the lead on the development of evidence reviews or dietary guidance for patients with diet-related health conditions. Several organizations, including AND, the National Association for the Advancement of Colored People, and the National Hispanic Medical Association, recently formed the Food4Health Alliance to advocate for additional federal nutrition guidelines tailored to the needs of tens of millions of Americans who have diet-related diseases such as hypertension, obesity, and type 2 diabetes—conditions that also disproportionately affect minorities and underserved communities (194)."}