PMC:7445716 / 2372-4185
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T7 | 272-278 | Body_part | denotes | tendon | http://purl.org/sig/ont/fma/fma9721 |
| T8 | 389-408 | Body_part | denotes | cerebrospinal fluid | http://purl.org/sig/ont/fma/fma20935 |
| T9 | 410-413 | Body_part | denotes | CSF | http://purl.org/sig/ont/fma/fma20935 |
| T10 | 762-771 | Body_part | denotes | brainstem | http://purl.org/sig/ont/fma/fma79876 |
| T11 | 979-995 | Body_part | denotes | Peripheral nerve | http://purl.org/sig/ont/fma/fma65239 |
| T12 | 1147-1158 | Body_part | denotes | ganglioside | http://purl.org/sig/ont/fma/fma82816 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T3 | 272-278 | Body_part | denotes | tendon | http://purl.obolibrary.org/obo/UBERON_0000043 |
| T4 | 389-408 | Body_part | denotes | cerebrospinal fluid | http://purl.obolibrary.org/obo/UBERON_0001359 |
| T5 | 762-771 | Body_part | denotes | brainstem | http://purl.obolibrary.org/obo/UBERON_0002298 |
| T6 | 990-995 | Body_part | denotes | nerve | http://purl.obolibrary.org/obo/UBERON_0001021 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T35 | 0-3 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T36 | 135-157 | Disease | denotes | polyradiculoneuropathy | http://purl.obolibrary.org/obo/MONDO_0006915 |
| T37 | 159-206 | Disease | denotes | acute inflammatory demyelinating polyneuropathy | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T38 | 178-206 | Disease | denotes | demyelinating polyneuropathy | http://purl.obolibrary.org/obo/MONDO_0003334 |
| T39 | 192-206 | Disease | denotes | polyneuropathy | http://purl.obolibrary.org/obo/MONDO_0001824 |
| T40 | 207-211 | Disease | denotes | AIDP | http://purl.obolibrary.org/obo/MONDO_0020347 |
| T41 | 324-327 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T42 | 509-512 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T43 | 554-576 | Disease | denotes | Miller Fisher syndrome | http://purl.obolibrary.org/obo/MONDO_0005851 |
| T44 | 578-581 | Disease | denotes | MFS | http://purl.obolibrary.org/obo/MONDO_0007947|http://purl.obolibrary.org/obo/MONDO_0019202|http://purl.obolibrary.org/obo/MONDO_0005851 |
| T47 | 594-606 | Disease | denotes | facial palsy | http://purl.obolibrary.org/obo/MONDO_0001835|http://purl.obolibrary.org/obo/MONDO_0005665 |
| T49 | 601-606 | Disease | denotes | palsy | http://purl.obolibrary.org/obo/MONDO_0006496 |
| T50 | 704-716 | Disease | denotes | polyneuritis | http://purl.obolibrary.org/obo/MONDO_0021718 |
| T51 | 728-731 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
| T52 | 732-735 | Disease | denotes | MFS | http://purl.obolibrary.org/obo/MONDO_0007947|http://purl.obolibrary.org/obo/MONDO_0019202|http://purl.obolibrary.org/obo/MONDO_0005851 |
| T55 | 750-784 | Disease | denotes | Bickerstaff brainstem encephalitis | http://purl.obolibrary.org/obo/MONDO_0019208 |
| T56 | 772-784 | Disease | denotes | encephalitis | http://purl.obolibrary.org/obo/MONDO_0019956 |
| T57 | 871-875 | Disease | denotes | AIDP | http://purl.obolibrary.org/obo/MONDO_0020347 |
| T58 | 877-906 | Disease | denotes | acute motor axonal neuropathy | http://purl.obolibrary.org/obo/MONDO_0020349 |
| T59 | 889-906 | Disease | denotes | axonal neuropathy | http://purl.obolibrary.org/obo/MONDO_0004183 |
| T60 | 896-906 | Disease | denotes | neuropathy | http://purl.obolibrary.org/obo/MONDO_0005244 |
| T61 | 908-912 | Disease | denotes | AMAN | http://purl.obolibrary.org/obo/MONDO_0020349 |
| T62 | 919-956 | Disease | denotes | acute motor sensory axonal neuropathy | http://purl.obolibrary.org/obo/MONDO_0020348 |
| T63 | 939-956 | Disease | denotes | axonal neuropathy | http://purl.obolibrary.org/obo/MONDO_0004183 |
| T64 | 946-956 | Disease | denotes | neuropathy | http://purl.obolibrary.org/obo/MONDO_0005244 |
| T65 | 958-963 | Disease | denotes | AMSAN | http://purl.obolibrary.org/obo/MONDO_0020348 |
| T66 | 1063-1073 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T67 | 1288-1297 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T68 | 1305-1316 | Disease | denotes | hepatitis E | http://purl.obolibrary.org/obo/MONDO_0005788 |
| T69 | 1305-1314 | Disease | denotes | hepatitis | http://purl.obolibrary.org/obo/MONDO_0002251 |
| T70 | 1328-1332 | Disease | denotes | Zika | http://purl.obolibrary.org/obo/MONDO_0018661 |
| T71 | 1382-1403 | Disease | denotes | Mycoplasma Pneumoniae | http://purl.obolibrary.org/obo/MONDO_0005867 |
| T72 | 1748-1756 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T73 | 1761-1764 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T18 | 272-278 | http://www.ebi.ac.uk/cellline#tendon | denotes | tendon |
| T19 | 272-278 | http://www.ebi.ac.uk/efo/EFO_0000952 | denotes | tendon |
| T20 | 525-526 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T21 | 990-995 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | nerve |
| T22 | 1224-1231 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T23 | 1275-1280 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T24 | 1298-1303 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T25 | 1317-1322 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T26 | 1333-1338 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T27 | 1344-1352 | http://purl.obolibrary.org/obo/NCBITaxon_2 | denotes | bacteria |
| T28 | 1428-1429 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T29 | 1461-1464 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T30 | 1593-1594 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T31 | 1694-1697 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T2 | 1147-1158 | Chemical | denotes | ganglioside | http://purl.obolibrary.org/obo/CHEBI_28892 |
| T3 | 1544-1554 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T4 | 1629-1633 | Chemical | denotes | beta | http://purl.obolibrary.org/obo/CHEBI_10545 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1044-1059 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune response |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 72 | 1262-1280 | Species | denotes | Epstein–Barr virus | Tax:10376 |
| 73 | 1288-1303 | Species | denotes | influenza virus | Tax:11308 |
| 74 | 1328-1338 | Species | denotes | Zika virus | Tax:64320 |
| 75 | 1360-1380 | Species | denotes | Campylobacter Jejuni | Tax:197 |
| 76 | 1382-1403 | Species | denotes | Mycoplasma Pneumoniae | Tax:2104 |
| 77 | 1629-1647 | Species | denotes | beta-coronaviruses | Tax:694002 |
| 78 | 1683-1691 | Species | denotes | MERS-CoV | Tax:1335626 |
| 79 | 1282-1285 | Species | denotes | EBV | Tax:10376 |
| 80 | 1147-1158 | Chemical | denotes | ganglioside | MESH:D005732 |
| 81 | 46-63 | Disease | denotes | flaccid paralysis | MESH:D010243 |
| 82 | 121-157 | Disease | denotes | demyelinating polyradiculoneuropathy | MESH:D020277 |
| 83 | 178-206 | Disease | denotes | demyelinating polyneuropathy | MESH:D003711 |
| 84 | 249-257 | Disease | denotes | weakness | MESH:D018908 |
| 85 | 259-287 | Disease | denotes | loss of deep tendon reflexes | MESH:D012021 |
| 86 | 293-309 | Disease | denotes | sensory deficits | MESH:D012678 |
| 87 | 578-581 | Disease | denotes | MFS | MESH:D008382 |
| 88 | 584-606 | Disease | denotes | bilateral facial palsy | MESH:D005158 |
| 89 | 704-726 | Disease | denotes | polyneuritis cranialis | MESH:D009443 |
| 90 | 732-735 | Disease | denotes | MFS | MESH:D008382 |
| 91 | 772-784 | Disease | denotes | encephalitis | MESH:D004660 |
| 92 | 877-906 | Disease | denotes | acute motor axonal neuropathy | MESH:D000208 |
| 93 | 919-956 | Disease | denotes | acute motor sensory axonal neuropathy | MESH:C536450 |
| 94 | 1063-1073 | Disease | denotes | infections | MESH:D007239 |
| 95 | 1560-1570 | Disease | denotes | malignancy | MESH:D009369 |
| 96 | 1649-1681 | Disease | denotes | Middle East Respiratory Syndrome | MESH:D018352 |
| 97 | 1748-1756 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T20 | 0-69 | Sentence | denotes | GBS represents the most common cause of acute flaccid paralysis [57]. |
| T21 | 70-310 | Sentence | denotes | The classic form is an immune-mediated acute-onset demyelinating polyradiculoneuropathy (acute inflammatory demyelinating polyneuropathy—AIDP) typically presenting with ascending weakness, loss of deep tendon reflexes, and sensory deficits. |
| T22 | 311-483 | Sentence | denotes | Diagnosis of GBS relies on the results of clinical, electrophysiological, and cerebrospinal fluid (CSF) examinations (classically albuminocytological dissociation) [57–59]. |
| T23 | 484-793 | Sentence | denotes | The clinical spectrum of GBS encompasses a classic sensorimotor form, Miller Fisher syndrome (MFS), bilateral facial palsy with paraesthesia, pure motor, pure sensory, paraparetic, pharyngeal–cervical–brachial variants, polyneuritis cranialis (GBS–MFS overlap), and Bickerstaff brainstem encephalitis [57–60]. |
| T24 | 794-978 | Sentence | denotes | As regard electrophysiological features, three main subtypes are recognized: AIDP, acute motor axonal neuropathy (AMAN), and acute motor sensory axonal neuropathy (AMSAN) [57, 58, 61]. |
| T25 | 979-1179 | Sentence | denotes | Peripheral nerve damage is thought to be provoked by an aberrant immune response to infections, in some cases driven by the production of autoreactive antibodies (anti-ganglioside antibodies) [57–59]. |
| T26 | 1180-1418 | Sentence | denotes | Potential triggering pathogens include both viruses [e.g., cytomegalovirus (CMV), Epstein–Barr virus (EBV), influenza virus, hepatitis E virus, and Zika virus] and bacteria (e.g., Campylobacter Jejuni, Mycoplasma Pneumoniae) [57, 58, 62]. |
| T27 | 1419-1581 | Sentence | denotes | However, a relationship with other events has been also described (e.g., vaccinations, surgery, administration of checkpoint inhibitors, and malignancy) [57, 58]. |
| T28 | 1582-1813 | Sentence | denotes | Given that a potential causal association with beta-coronaviruses [Middle East Respiratory Syndrome (MERS-CoV)] has already been speculated, the relationship between COVID-19 and GBS deserves undoubtedly further attention [63, 64]. |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T3 | 54-63 | Phenotype | denotes | paralysis | http://purl.obolibrary.org/obo/HP_0003470 |
| T4 | 121-134 | Phenotype | denotes | demyelinating | http://purl.obolibrary.org/obo/HP_0011096 |
| T5 | 178-191 | Phenotype | denotes | demyelinating | http://purl.obolibrary.org/obo/HP_0011096 |
| T6 | 192-206 | Phenotype | denotes | polyneuropathy | http://purl.obolibrary.org/obo/HP_0001271 |
| T7 | 259-287 | Phenotype | denotes | loss of deep tendon reflexes | http://purl.obolibrary.org/obo/HP_0001284 |
| T8 | 584-606 | Phenotype | denotes | bilateral facial palsy | http://purl.obolibrary.org/obo/HP_0430025 |
| T9 | 704-716 | Phenotype | denotes | polyneuritis | http://purl.obolibrary.org/obo/HP_0031003 |
| T10 | 772-784 | Phenotype | denotes | encephalitis | http://purl.obolibrary.org/obo/HP_0002383 |
| T11 | 883-906 | Phenotype | denotes | motor axonal neuropathy | http://purl.obolibrary.org/obo/HP_0007002 |
| T12 | 931-956 | Phenotype | denotes | sensory axonal neuropathy | http://purl.obolibrary.org/obo/HP_0003390 |
| T13 | 979-1002 | Phenotype | denotes | Peripheral nerve damage | http://purl.obolibrary.org/obo/HP_0009830 |
| T14 | 1305-1314 | Phenotype | denotes | hepatitis | http://purl.obolibrary.org/obo/HP_0012115 |
| T15 | 1393-1403 | Phenotype | denotes | Pneumoniae | http://purl.obolibrary.org/obo/HP_0002090 |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T28 | 93-99 | UBERON:0002405 | denotes | immune |
| T29 | 272-278 | UBERON:0000043 | denotes | tendon |
| T30 | 279-287 | GO:0060004 | denotes | reflexes |
| T31 | 389-408 | UBERON:0001359 | denotes | cerebrospinal fluid |
| T32 | 535-547 | UBERON:0025534 | denotes | sensorimotor |
| T33 | 594-600 | UBERON:0001456 | denotes | facial |
| T34 | 665-675 | UBERON:0006562 | denotes | pharyngeal |
| T35 | 676-684 | UBERON:0005434 | denotes | cervical |
| T36 | 685-693 | UBERON:0001460 | denotes | brachial |
| T37 | 762-771 | UBERON:0002298 | denotes | brainstem |
| T38 | 889-895 | GO:0030424 | denotes | axonal |
| T39 | 939-945 | GO:0030424 | denotes | axonal |
| T40 | 979-995 | UBERON:0001021 | denotes | Peripheral nerve |
| T41 | 1044-1050 | UBERON:0002405;GO:0006955 | denotes | immune |
| T42 | 1051-1059 | GO:0006955 | denotes | response |
| T43 | 1130-1140 | GO:0042571 | denotes | antibodies |
| T44 | 1147-1158 | CHEBI:5386;CHEBI:5386 | denotes | ganglioside |
| T45 | 1159-1169 | GO:0042571 | denotes | antibodies |
| T46 | 1224-1231 | NCBITaxon:10376 | denotes | viruses |
| T47 | 1239-1254 | NCBITaxon:10358 | denotes | cytomegalovirus |
| T48 | 1256-1259 | NCBITaxon:10358 | denotes | CMV |
| T49 | 1262-1280 | NCBITaxon:10376 | denotes | Epstein–Barr virus |
| T50 | 1282-1285 | NCBITaxon:10376 | denotes | EBV |
| T51 | 1288-1297 | NCBITaxon:7719 | denotes | influenza |
| T52 | 1298-1303 | NCBITaxon:10376 | denotes | virus |
| T53 | 1305-1316 | NCBITaxon:10376 | denotes | hepatitis E |
| T54 | 1317-1322 | NCBITaxon:10239 | denotes | virus |
| T55 | 1328-1332 | NCBITaxon:7955 | denotes | Zika |
| T56 | 1333-1338 | NCBITaxon:10239 | denotes | virus |
| T57 | 1344-1352 | NCBITaxon:2 | denotes | bacteria |
| T58 | 1360-1380 | NCBITaxon:197 | denotes | Campylobacter Jejuni |
| T59 | 1382-1403 | NCBITaxon:2104 | denotes | Mycoplasma Pneumoniae |
| T60 | 1533-1543 | GO:0000075 | denotes | checkpoint |
| T61 | 1544-1554 | CHEBI:35222;CHEBI:35222 | denotes | inhibitors |
| T62 | 1634-1647 | NCBITaxon:11118 | denotes | coronaviruses |
| T63 | 1683-1691 | SP_9 | denotes | MERS-CoV |
| T64 | 1748-1756 | SP_7 | denotes | COVID-19 |
| T6430 | 93-99 | UBERON:0002405 | denotes | immune |
| T42852 | 272-278 | UBERON:0000043 | denotes | tendon |
| T93969 | 279-287 | GO:0060004 | denotes | reflexes |
| T60468 | 389-408 | UBERON:0001359 | denotes | cerebrospinal fluid |
| T8794 | 535-547 | UBERON:0025534 | denotes | sensorimotor |
| T20510 | 594-600 | UBERON:0001456 | denotes | facial |
| T22353 | 665-675 | UBERON:0006562 | denotes | pharyngeal |
| T47521 | 676-684 | UBERON:0005434 | denotes | cervical |
| T16287 | 685-693 | UBERON:0001460 | denotes | brachial |
| T65493 | 762-771 | UBERON:0002298 | denotes | brainstem |
| T84677 | 889-895 | GO:0030424 | denotes | axonal |
| T3745 | 939-945 | GO:0030424 | denotes | axonal |
| T84301 | 979-995 | UBERON:0001021 | denotes | Peripheral nerve |
| T92975 | 1044-1050 | UBERON:0002405;GO:0006955 | denotes | immune |
| T53844 | 1051-1059 | GO:0006955 | denotes | response |
| T68274 | 1130-1140 | GO:0042571 | denotes | antibodies |
| T56699 | 1147-1158 | CHEBI:5386;CHEBI:5386 | denotes | ganglioside |
| T33354 | 1159-1169 | GO:0042571 | denotes | antibodies |
| T29794 | 1224-1231 | NCBITaxon:10376 | denotes | viruses |
| T20681 | 1239-1254 | NCBITaxon:10358 | denotes | cytomegalovirus |
| T78305 | 1256-1259 | NCBITaxon:10358 | denotes | CMV |
| T76697 | 1262-1280 | NCBITaxon:10376 | denotes | Epstein–Barr virus |
| T91212 | 1282-1285 | NCBITaxon:10376 | denotes | EBV |
| T17853 | 1288-1297 | NCBITaxon:7719 | denotes | influenza |
| T95830 | 1298-1303 | NCBITaxon:10376 | denotes | virus |
| T99746 | 1305-1316 | NCBITaxon:10376 | denotes | hepatitis E |
| T38360 | 1317-1322 | NCBITaxon:10239 | denotes | virus |
| T23161 | 1328-1332 | NCBITaxon:7955 | denotes | Zika |
| T94360 | 1333-1338 | NCBITaxon:10239 | denotes | virus |
| T43117 | 1344-1352 | NCBITaxon:2 | denotes | bacteria |
| T66998 | 1360-1380 | NCBITaxon:197 | denotes | Campylobacter Jejuni |
| T94241 | 1382-1403 | NCBITaxon:2104 | denotes | Mycoplasma Pneumoniae |
| T95916 | 1533-1543 | GO:0000075 | denotes | checkpoint |
| T13087 | 1544-1554 | CHEBI:35222;CHEBI:35222 | denotes | inhibitors |
| T44436 | 1634-1647 | NCBITaxon:11118 | denotes | coronaviruses |
| T44433 | 1683-1691 | SP_9 | denotes | MERS-CoV |
| T35938 | 1748-1756 | SP_7 | denotes | COVID-19 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32840686-31541214-63205623 | 65-67 | 31541214 | denotes | 57 |
| 32840686-31541214-63205624 | 476-478 | 31541214 | denotes | 57 |
| 32840686-26948435-63205624 | 476-478 | 26948435 | denotes | 57 |
| 32840686-30310069-63205624 | 476-478 | 30310069 | denotes | 57 |
| 32840686-31541214-63205625 | 786-788 | 31541214 | denotes | 57 |
| 32840686-26948435-63205625 | 786-788 | 26948435 | denotes | 57 |
| 32840686-30310069-63205625 | 786-788 | 30310069 | denotes | 57 |
| 32840686-26369515-63205625 | 786-788 | 26369515 | denotes | 57 |
| 32840686-31541214-63205626 | 966-968 | 31541214 | denotes | 57 |
| 32840686-26948435-63205627 | 970-972 | 26948435 | denotes | 58 |
| 32840686-30419502-63205628 | 974-976 | 30419502 | denotes | 61 |
| 32840686-31541214-63205629 | 1172-1174 | 31541214 | denotes | 57 |
| 32840686-26948435-63205629 | 1172-1174 | 26948435 | denotes | 57 |
| 32840686-30310069-63205629 | 1172-1174 | 30310069 | denotes | 57 |
| 32840686-31541214-63205630 | 1406-1408 | 31541214 | denotes | 57 |
| 32840686-26948435-63205631 | 1410-1412 | 26948435 | denotes | 58 |
| 32840686-32518150-63205632 | 1414-1416 | 32518150 | denotes | 62 |
| 32840686-31541214-63205633 | 1573-1575 | 31541214 | denotes | 57 |
| 32840686-26948435-63205634 | 1577-1579 | 26948435 | denotes | 58 |
| 32840686-32860084-63205635 | 1809-1811 | 32860084 | denotes | 64 |