PMC:7445716 / 16263-39994 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7445716","sourcedb":"PMC","sourceid":"7445716","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7445716","text":"Article Country Age Sex GBS clinical picture COVID-19 clinical picture Previous comorbidities GBS diagnosis Level of diagnostic certaintyb GBS variant\nDays between COVID-19 symptoms and GBS onset Onset Disease course Autonomic disturbances Respiratory symptoms/failure Time to Nadira\nAgosti et al. [5] Italy 68 M 5 days after LL weakness Bilateral facial palsy, progressive symmetric ascending flaccid tetraparesis, achilles tendon areflexia NA No NA Dry cough associated with fever, dysgeusia, and hyposmia Dyslipidemia, benign prostatic hypertrophy, hypertension, abdominal aortic aneurysm Clinical + CSF + electrophysiology 1 Pure motor\nAlberti et al. [6] Italy 71 M 4 days after (no resolution of pneumonia) LL paraesthesia Ascendant weakness, flaccid tetraparesis, hypoesthesia and paraesthesia in the 4 limbs, generalized areflexia, dyspnea None Yes (concurrent pneumonia) 4 days after symptoms onset (24 h after the admission) Fever (low grade), dyspnea, pneumonia Hypertension, treated abdominal aortic aneurysm, treated lung cancer Clinical + CSF + electrophysiology 1 Classic sensorimotor\nArnaud et al. [7] France 64 M 23 days after Fast progressive LL weakness Generalized areflexia, severe flaccid proximal paraparesis, decreased proprioceptive length-dependent sensitivity and LL pinprick and light touch hypoesthesia None No 4 days after symptoms onset Fever, cough, diarrhea, dyspnea, severe interstitial pneumonia DM type 2 Clinical + CSF + electrophysiology 1 Classic sensorimotor\nAssini et al. [8] Italy 55 M 20 days after Bilateral eyelid ptosis, dysphagia, dysphonia Masseter weakness, tongue protusion (bilateral hypoglossal nerve paralysis), UL and LL hyporeflexia without muscle weakness, soft palate elevation defect None Yes (concurrent pneumonia) NA Fever, anosmia, ageusia, cough, pneumonia NA Clinical + electrophysiology 2 Classic sensorimotor overlapping with Miller-Fisher\nAssini et al. [8] Italy 60 M 20 days after Distal tetraparesis with right foot drop, autonomic disturbances UL and LL distal weakness, right foot drop, generalized areflexia Gastroplegia, paralytic ileus, loss of blood pressure control Yes (concurrent pneumonia) NA Fever, severe interstitial pneumonia NA Clinical + electrophysiology 2 Pure motor\nBigaut et al. [9] France 43 M 21 days after UL and LL paraesthesia, distal LL weakness Extension to midthigh and tips of the finger with ataxia, right peripheral facial nerve palsy, generalized areflexia None No 2 days after symptoms onset Cough, asthenia, myalgia in legs, followed by acute anosmia and ageusia with diarrhea, mild interstitial pneumonia NA Clinical + CSF + electrophysiology 1 Classic sensorimotor\nBigaut et al. [9] France 70 F 10 days after Acute proximal tetraparesis, distal forelimb and perioral paraesthesia Respiratory weakness, loss of ambulation None Yes 3 days after symptoms onset Anosmia, ageusia, diarrhea, asthenia, myalgia, moderate interstitial pneumonia Obesity Clinical + CSF + electrophysiology 1 Classic sensorimotor\nBracaglia et al. [10] Italy 66 F Unknown (due to asymptomatic infection) Acute proximal and distal tetraparesis, lumbar pain and distal tingling sensation Loss of ambulation, difficulty in speeching and swallowing, generalized areflexia None No NA Asymptomatic None Clinical + electrophysiology 2 Classic sensorimotor\nCamdessanche et al. [11] France 64 M 11 days after UL and LL paraesthesia Ascendent weakness, flaccid tetraparesis, generalized areflexia, dysphagia None Yes 3 days after symptoms onset Fever (high grade), cough, pneumonia None Clinical + CSF + electrophysiology 1 Classic sensorimotor\nChan et al. [12] Canada 58 M 20 days after home isolation for suspected contact Bilateral facial weakness, dysarthria, feet paraesthesia, LL areflexia NA None No NA Asymptomatic, interstitial pneumonia None Clinical + CSF + electrophysiology 1 Bilateral facial palsy\nwith paraesthesia\nChan et al. [13] USA 68 M 18 days after Gait disturbance, hands and feet paraesthesia LL proximal weakness, absent vibratory and proprioceptive sense at the toes, UL hyporeflexia, LL areflexia, unsteady gait with inability to toe or heel walk, bilateral facial weakness, dysphagia, dysarthria, neck flexion weakness None No 8 days after the onset of symptoms Fever and upper respiratory symptoms NA Clinical + CSF 2 Classic sensorimotor\nChan et al. [13] USA 84 M 16 days after Hands and feet paraesthesia, progressive gait disturbance Bilateral facial weakness, progressive arm weakness, neuromuscular respiratory failure Yes (not specified autonomic dysfunction) Yes 25 days after the onset of symptoms Fever NA Clinical + CSF 2 Classic sensorimotor\nCoen et al. [14] Switzerland 70 M 6 days after Paraparesis, distal allodynia Generalized areflexia Difficulties in voiding and constipation No NA Dry cough, myalgia, fatigue None Clinical + CSF + 0electrophysiology 1 Classic sensorimotor\nEbrahimzadeh et al. [15] Iran 46 M 18 days after Pain and numbness in distal LL and UL extremities, ascending weakness in legs Mild peripheral right facial nerve palsy, generalized areflexia None No 7 days after symptoms onset Low-grade fever, sore thorat, dry cough and mild dyspnea, bilateral interstitial pneumonia (concurrent with neurological symptoms) None Clinical + CSF + electrophysiology 1 Classic sensorimotor\nEbrahimzadeh et al. [15] Iran 65 M 10 days after Progressive ascending LL and UL extremities weakness and paraesthesia Proximal and distal UL and LL weakness, UL hyporeflexia and LL areflexia None No 14 days after symptoms onset History of COVID-19 (symptoms not specified), fine crackles in both lungs (concurrent with neurological symptoms) Hypertension Clinical + electrophysiology 2 Classic sensorimotor\nEl Otmani et al. [16] Morocco 70 F 3 days after Weakness and paraesthesia in the 4 limbs Tetraparesis, hypotonia, generalized areflexia, bilateral positive Lasègue sign None No NA Dry cough, pneumonia Rheumatoid arthritis Clinical + CSF + electrophysiology 1 Classic sensorimotor\nEsteban Molina et al. [17] Spain 55 F 14 days after Paraesthesia and weakness in the 4 limbs Lumbar pain, dysphagia, tetraplegia, general areflexia, bilateral facial palsy, lingual and perioral paraesthesia None Yes 3 days after symptoms onset (48 h after the admission) Fever, dry cough and dyspnoea, pneumonia Dyslipidemia Clinical + CSF + electrophysiology 1 Classic sensorimotor\nFarzi et al. [18] Iran 41 M 10 days after Paraesthesia of the feet Tetraparesis, areflexia at the LL and hyporeflexia at the UL, stocking-and-glove hypesthesia and reduced sense of vibration and position None No 7 days after symptoms onset Cough, dyspnea and fever DM type II Clinical + electrophysiology 2 Classic sensorimotor\nFernández–Domínguez et al. [19] Spain 74 F 15 days after Gait ataxia and generalized areflexia NA NA No NA Respiratory symptoms (not further detailed) Hypertension and follicular lymphoma Clinical + CSF 2 Miller Fisher variant\nFinsterer et al. [20] India 20 M 5 days after NA NA NA NA NA NA NA Clinical + electrophysiology 2 NA\nFrank et al. [21] Brazil 15 M \u003e 5 days after Paraparesis, pain in the LL Rapidly progressive ascending tetraparesis, areflexia NA No NA Fever, intense sweating NA Clinical + electrophysiology 2 Classic sensorimotor\nGigli et al. [22] Italy 53 M NA Paraesthesia, gait ataxia NA NA NA NA Fever, diarrhea NA Clinical + CSF + electrophysiology 1 NA\nGutiérrez-Ortiz et al. [23] Spain 50 M 3 days after Vertical diplopia, perioral paraesthesia, gait ataxia Right internuclear ophthalmoparesis and right fascicular oculomotor palsy, ataxia, generalized areflexia None No NA Fever, cough, malaise, headache, low back pain, anosmia, ageusia Bronchial asthma Clinical + CSF 2 Miller Fisher variant\nGutiérrez-Ortiz et al. [23] Spain 39 M 3 days after Diplopia (bilateral abducens palsy) Generalized areflexia None No NA Diarrhea, low-grade fever None Clinical + CSF 2 Polyneuritis cranialis (GBS–Miller Fisher Interface)\nHelbok et al. [24] Austria 68 M 14 days after Hypoaesthesia and paraesthesia in the LL, proximal weakness, areflexia, stand ataxia Ascending weakness, flaccid tetraparesis, generalized areflexia NA Yes 2 days after symptoms onset (24 h after the admission) Fever, dry cough, myalgia, anosmia and ageusia. None Clinical + CSF + electrophysiology 1 Classic sensorimotor\nHutchins et al. [25] USA 21 M 16 days after Right-sided facial numbness and weakness Bilateral facial palsy, severe dysarthria, bilateral LL weakness , bilateral UL paraesthesia, areflexia NA No 3 days after symptoms onset Fever, cough, dyspnoea, diarrhea, nausea, headache Hypertension, prediabetes, and class I obesity Clinical + CSF + electrophysiology 1 Bilateral facial palsy with paraesthesia\nJuliao Caamaño et al. [26] Spain 61 M 10 days after Facial diplegia No progression None No 1 day after symptoms onset Fever and cough None Clinical + electrophysiology 3 Bilateral facial nerve palsy\nKhalifa et al. [27] Kingdom of Saudi Arabia 11 M 20 days after Gait ataxia, areflexia and paraesthesia in the LL Gradual motor improvement, persistent hyporeflexia NA No NA Acute upper respiratory tract infection, low-grade fever, dry cough. NA Clinical + CSF + electrophysiology 1 Classic sensorimotor\nKilinc et al. [28] The Netherlands 50 M 24 days after Facial diplegia, symmetrical proximal weakness, paraesthesia of distal extremities, gait ataxia, areflexia Progression of limb weakness and inability to walk NA No 11 days after symptoms onset Dry cough None Clinical + electrophysiology 2 Classic sensorimotor\nLampe et al. [29] Germany 65 M 2 days after Acute right UL and LL weakness causing recurrent falls Right UL paresis, slight paraparesis more pronounced on the right side, generalized hyporeflexia None No 3 days after symptoms onset Fever and dry cough None Clinical + CSF + electrophysiology 1 Pure motor\nLantos et al. [30] USA 36 M 4 days after Opthalmoparesisa and hypoesthesia below knee Progressive ophthalmoparesis (including initial left III cranial nerve and eventual bilateral VI cranial nerve palsies), ataxia, and hyporeflexia None No NA Fever, chills, and myalgia None Clinical 3 Miller Fisher variant\nLascano et al. [31] Switzerland 52 F 15 days after (no resolution of pneumonia) Back pain, diarrhea, rapidly progressive tetraparesis, distal paraesthesia Worsening of proximal weakness (tetraplegia), generalized areflexia, ataxia Constipation, abdominal pain Yes 4 days after symptoms onset Dry cough, dysgeusia, cacosmia None Clinical + CSF + electrophysiology 1 Classic sensorimotor\nLascano et al. [31] Switzerland 63 F 7 days after (no resolution of pneumonia) Limb weakness, pain on the left calf Moderate tetraparesis, LL and left UL areflexia, distal hypoesthesia and paraesthesia None No 5 days after symptoms onset Dry cough, shivering, breathing difficulties, chest pain, odynophagia DM type 2 Clinical + electrophysiology 2 Classic sensorimotor\nLascano et al. [31] Switzerland 61 F 22 days after LL weakness, dizziness, dysphagia Moderate tetraparesis, bilateral facial palsy, lower limb allodynia, severe hypopallesthesia, areflexia (except for bicipital tendon reflexes) None Yes 4 days after symptoms onset Productive cough, headaches, fever, myalgia, diarrhea, nausea, vomiting, weight loss, recurrent episodes of transient loss of consciousness None Clinical + CSF + electrophysiology 1 Classic sensorimotor\nManganotti et al. [32] Italy 50 F 16 days after Diplopia and facial paraesthesia Ataxia, diplopia in vertical and lateral gaze, left upper arm dysmetria, generalized areflexia, mild lower facial defects, and mild hypoesthesia in the left mandibular and maxillary branch None Yes (concurrent pneumonia) NA Fever, cough, ageusia, bilateral pneumonia None Clinical + CSF 2 Miller Fisher variant\nManganotti et al. [33] Italy 72 M 18 days after Tetraparesis UL \u003e LL, LL paraesthesia , generalized areflexia, facial weakness on the right side NA NA No NA Fever, dyspnea, hyposmia and ageusia NA Clinical + CSF + electrophysiology 1 Classic sensorimotor\nManganotti et al. [33] Italy 72 M 30 days after Tetraparesis LL \u003e UL, paraesthesia, global areflexia NA NA No NA Fever, cough, dyspnea, hyposmia and ageusia NA Clinical + electrophysiology 1 Classic sensorimotor\nManganotti et al. [33] Italy 49 F 14 days after Ophthalmoplegia, limb ataxia, generalized areflexia, diplopia, facial hypoesthesia, facial weakness NA NA No NA Fever, cough, dyspnea, hyposmia and ageusia NA Clinical + CSF + electrophysiology 1 Miller Fisher variant\nManganotti et al. [33] Italy 94 M 33 days after LL weakness, generalized hyporeflexia NA NA No NA Fever, cough, gastrointestinal symptoms NA Clinical + electrophysiology 2 Classic sensorimotor\nManganotti et al. [33] Italy 76 M 22 days after Quadriparesis UL \u003e LL, generalized areflexia, facial weakness, transient diplopia NA NA No NA Fever, cough, dysuria, hyposmia, ageusia NA Clinical + CSF + electrophysiology 1 Pure motor\nMarta-Enguita et al. [34] Spain 76 F 8 days after Back pain and progressive tetraparesis with distal-onset paraesthesia Progressive with dysphagia and cranial nerves involvement, generalized areflexia NA Yes 10 days after symptom onset Cough and fever without dyspnea None Clinical 3 NA\nMozhdehipanah et al. [35] Iran 38 M 16 days after Progressive LL paraesthesia, facial diplegia, lobal areflexia Mild LL weakness , bulbar symptoms developed Blood pressure instability, tachycardia No 8 days after symptoms onset Upper respiratory infection (no further details) NA Clinical + CSF + electrophysiology 1 Bilateral facial palsy with paraesthesia\nMozhdehipanah et al. [35] Iran 14 F NA Ascending quadriparesis, UL hyporeflexia, LL areflexia, distal hypoesthesia, ataxia NA NA No NA Upper respiratory infection (no further details) NA Clinical + CSF 2 Classic sensorimotor\nMozhdehipanah et al. [35] Iran 44 F 26 days after Weakness of LL Tetraparesis, generalized areflexia, symmetrical hypoesthesia NA Yes NA Dry cough, fever, myalgia, progressive dyspnea COPD Clinical + CSF + electrophysiology 1 Classic sensorimotor\nMozhdehipanah et al. [35] Iran 66 F 30 days after Progressive UL and LL weakness, generalized areflexia, symmetrical hypoesthesia NA No No NA Fever, dry cough, severe myalgia DM, hypertension, and rheumatoid arthritis Clinical + CSF + electrophysiology 1 Classic sensorimotor\nNaddaf et al. [36] USA 58 F 17 days after Progressive paraparesis, imbalance, severe lower thoracic pain without radiation Mild neck flexion weakness, mild/moderate distal UL  and proximal and distal LL  weakness, UL hyporeflexia, LL areflexia, moderately severe length-dependent sensory loss in the feet, ataxic gait None No NA Fever, dysgeusia without anosmia, bilateral interstitial pneumonia None Clinical + CSF + electrophysiology 1 Classic sensorimotor\nOguz-Akarsu et al. [37] Turkey 53 F Concurrent pneumonia Dysarthria, progressive LL weakness and numbness Ataxia, generalized areflexia None No NA Mild fever (37.5 °C), pneumonia None Clinical + electrophysiology 2 Classic sensorimotor\nOttaviani et al. [38] Italy 66 F 7 days after (concurrent pneumonia) Flaccid paraparesis, no sensory symptoms Progressively developed proximal weakness in all limbs, dysesthesia, and unilateral facial palsy, generalized areflexia NA Yes 13 days after symptoms onset Fever and cough, pneumonia NA Clinical + CSF + electrophysiology 1 Classic sensorimotor\nPadroni et al. [39] Italy 70 F 23 days after UL and LL paraesthesia, gait difficulties, asthenia Ascendant weakness, tetraparesis, generalized areflexia None Yes 6 days after symptoms onset Fever (38.5 °C), dry cough, pneumonia None Clinical + CSF + Electrophysiology 1 Classic sensorimotor\nPaterson et al. [40] UK 42 M 13 day after Distal limb numbness and weakness, dysphagia Tetraparesis, generalized areflexia, sensory loss NA Yes 16 days after symptom onset Cough, fever dyspnea, diarrhea, anosmia None Clinical + CSF + electrophysiology 1 Classic sensorimotor\nPaterson et al. [40] UK 60 M 1 day before Distal limb numbness and weakness Tetraparesis, generalized areflexia, sensory loss, dysautonomia, facial and bulbar weakness Yes Yes 5 days after symptom onset Headache, ageusia, anosmia NA Clinical + CSF + electrophysiology 1 Classic sensorimotor\nPaterson et al. [40] UK 38 M 21 day after Distal limb numbness, weakness, clumsiness Mild distal weakness, sensory ataxia None No NA Cough, diarrhea NA Clinical + CSF + electrophysiology 1 Classic sensorimotor\nPaybast et al. [41] Iran 38 M 21 days after Acute progressive ascending paraesthesia of distal LL Quadriparesthesia, bilateral facial droop with drooling of saliva and slurred speech, generalized areflexia, swallowing inability, bilaterally absent gag reflex Tachycardia and blood pressure instability No 3 days after symptoms onset Symptoms of upper respiratory tract infection Hypertension Clinical + CSF + electrophysiology 1 Classic sensorimotor\nPaybast et al. [41] Iran 14 F 21 days after Progressive ascending quadriparesthesia, mild LL weakness Mild proximal and distal LL weakness, hypoactive deep tendon reflexes in UL and absent in LL, decreased light touch, position, and vibration sensation in all distal limbs up to ankle and elbow joints, gait ataxia None No 2 days after symptoms onset Symptoms of upper respiratory tract infection None Clinical + CSF 2 Classic sensorimotor\nPfefferkorn et al. [42] Germany 51 M 14 days after UL and LL weakness, acral paraesthesia Tetraparesis, generalized areflexia, deterioration to an almost complete peripheral locked-in syndrome with tetraplegia, complete sensory loss at 4 limbs, bilateral facial and hypoglossal paresis None Yes 15 days after symptoms onset Fluctuating fever, flu-like symptoms with marked fatigue and dry cough, pneumonia NA Clinical + CSF + electrophysiology 1 Classic sensorimotor\nRana et al. [43] USA 54 M 14 days after LL paresthesias of LL Ascending tetraparesis, general areflexia, burning sensation diplopia, facial diplegia, mild ophthalmoparesis Resting tachycardia and urinary retention Yes NA Rhinorrhea, odynophagia, fever, chills, and night sweats Hypertension, hyperlipidemia, restless leg syndrome, and chronic back pain, concurrent C. Difficile infection Clinical + electrophysiology 2 Miller Fisher variant\nReyes-Bueno et al. [44] Spain 50 F 15 days after Root-type pain in all four limbs, dorsal and lumbar back pain LL Weakness, ataxia, diplopia, bilateral facial palsy, generalized areflexia Dry mouth, diarrhea and unstable blood pressure No 12 days after symptoms onset Diarrhea, odynophagia and cough NA Clinical + CSF + electrophysiology 1 Miller Fisher variant\nRiva et al. [45] Italy 60+ M 17 days after Progressive limb weakness and distal paresthesia at four limbs Ascending paraparesis with involvement of the cranial nerves (facial diplegia), generalized areflexia None No 10 days after symptoms onset Fever, headache, myalgia, anosmia and ageusia NA Clinical + electrophysiology 2 Classic sensorimotor\nSancho-Saldaña et al. [46] Spain 56 F 15 days after Unsteadiness and paraesthesia in both hands Lumbar pain and ascending weakness, global areflexia, bilateral facial nerve palsy, oropharyngeal weakness and severe proximal tetraparesis No Yes 3 days after symptoms onset Fever, dry cough and dyspnea, pneumonia NA Clinical + CSF + electrophysiology 1 Classic sensorimotor\nScheidl et al. [47] Germany 54 F 11 days after Proximal weakness of LL, numbness of 4 limbs Initial worsening of the paraparesis with rapid improvement upon initiation of the treatment, areflexia None No 12 days after symptoms onset Temporary ageusia, None Clinical + CSF + electrophysiology 1 Paraparetic variant\nSedaghat et al. [48] Iran 65 M 14 days after LL distal weakness Ascending weakness, tetraparesis, facial bilateral palsy, generalized areflexia, LL distal hypoesthesia and hypopallesthesia None No 4 days after symptoms onset Fever, cough and sometimes dyspnea, pneumonia DM type 2 Clinical + electrophysiology 2 Classic sensorimotor\nSidig et al. [49] Sudan 65 M 5 days after Numbness and weakness in both UL and LL Ascending weakness, bilateral facial paraesthesia and palsy, clumsiness of UL, tetraparesis, slight palatal muscle weakness, areflexia Urinary incontinence Yes NA Low-grade fever, sore throat, dry cough, headache and generalized fatigability DM and Hypertension Clinical + electrophysiology 2 Classic sensorimotor\nSu et al. [50] USA 72 M 6 days after Proximal UL and LL weakness Progression with worsening of the paresis, areflexia, hypoesthesia Hypotension alternating with hypertension and tachycardia Yes 8 days after symptoms onset Mild diarrhea, anorexia and chills without fever or respiratory symptoms Coronary artery disease, hypertension and alcohol abuse Clinical + CSF + electrophysiology 1 Classic sensorimotor\nTiet et al. [51] United Kingdom 49 M 21 days after Distal LL paraesthesia LL and UL weakness, facial diplegia, distal reduced sensation to pinprick and vibration sense, LL dysesthesia, generalized areflexia None No 4 days after symptoms onset Shortness of breath, headache and cough Sinusitis Clinical + CSF + electrophysiology 1 Classic sensorimotor\nToscano et al. [52] Italy 77 F 7 days after UL and LL paraesthesia Flaccid tetraplegia, areflexia, facial weakness, dysphagie, tongue weakness None Yes NA Fever, cough, ageusia, pneumonia Previous ischemic stroke, diverticulosis, arterial hypertension, atrial fibrillation Clinical + CSF + electrophysiology 1 Classic sensorimotor\nToscano et al. [52] Italy 23 M 10 days after Facial diplegia LL paraesthesia, generalized areflexia, sensory ataxia None No 2 days after symptoms onset Fever, pharyngitis NA Clinical + CSF + electrophysiology 1 Bilateral facial palsy with paraesthesia\nToscano et al. [52] Italy 55 M 10 days after Neck pain, Paresthesias in the 4 limbs, LL weakness Flaccid tetraparesis, areflexia, facial weakness None Yes NA Fever, cough, pneumonia NA Clinical + CSF + electrophysiology 1 Classic sensorimotor\nToscano et al. [52] Italy 76 M 5 days after Lumbar pain, LL weakness Flaccid tetraparesis, generalized areflexia, ataxia None No 4 days after symptoms onset Cough and hyposmia NA Clinical + CSF+\nElectrophysiology 1 Classic sensorimotor\nToscano et al. [52] Italy 61 M 7 days after LL weakness and paraesthesia Ascending weakness, tetraplegia, facial weakness, areflexia, dysphagia None Yes NA Cough, ageusia and anosmia, pneumonia NA Clinical + CSF+ electrophysiology 1 Classic sensorimotor\nVelayos Galán et al. [53] Spain 43 M 10 days after Distal weakness and numbness of the 4 limbs, gait ataxia Progression of the weakness with bilateral facial paresis and dysphagia, generalized areflexia NA No 2 days after admission Cough, pneumonia NA Clinical + electrophysiology 2 Classic sensorimotor\nVirani et al. [54] USA 54 M 8 days after LL weakness, numbness Ascending weakness, tetraparesis, areflexia Urinary retention Yes Shortly after presentation in the outpatient clinic (after 2 days of symptoms onset) Fever (102 F), dry cough, pneumonia Clostridium difficile colitis 2 days before GBS onset Clinical 3 Classic sensorimotor\nWebb et al. [55] United Kingdom 57 6 days after Ataxia, progressive limb weakness and foot dysaesthesia, Tetraparesis, generalized areflexia, hypoesthesia in the 4 limbs, hypopallesthesia in LL, dysphagia None Yes 3 days after symptoms onset Mild cough and headache, myalgia and malaise, slight fever, diarrhea, pneumonia Untreated hypertension and psoriasis Clinical + CSF + electrophysiology 1 Classic sensorimotor\nZhao et al. [56] China 61 F 8 days before LL weakness Ascending weakness, tetraparesis, areflexia, LL distal hypoesthesia None No 4 days after symptoms onset Fever (38·2 °C), dry cough pneumonia NA Clinical + CSF + electrophysiology 1 Classic 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