PMC:7443692 / 9613-13789
Annnotations
LitCovid-sample-MedDRA
Id | Subject | Object | Predicate | Lexical cue | meddra_id |
---|---|---|---|---|---|
T10 | 2953-2963 | http://purl.bioontology.org/ontology/MEDDRA/10022891 | denotes | microscopy | http://purl.bioontology.org/ontology/MEDDRA/10069374 |
T11 | 3144-3150 | http://purl.bioontology.org/ontology/MEDDRA/10022891 | denotes | weight | http://purl.bioontology.org/ontology/MEDDRA/10047890 |
LitCovid-sample-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T38 | 67-79 | Chemical | denotes | Glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
T39 | 557-560 | Chemical | denotes | SDS | http://purl.obolibrary.org/obo/CHEBI_8984 |
T40 | 703-711 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
T41 | 1012-1019 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T42 | 1054-1063 | Chemical | denotes | glutamine | http://purl.obolibrary.org/obo/CHEBI_28300 |
T43 | 1104-1117 | Chemical | denotes | pyroglutamine | http://purl.obolibrary.org/obo/CHEBI_133469 |
T44 | 1190-1197 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
T45 | 1239-1242 | Chemical | denotes | Asn | http://purl.obolibrary.org/obo/CHEBI_17196|http://purl.obolibrary.org/obo/CHEBI_22653|http://purl.obolibrary.org/obo/CHEBI_50347 |
T48 | 1346-1349 | Chemical | denotes | Cys | http://purl.obolibrary.org/obo/CHEBI_29950|http://purl.obolibrary.org/obo/CHEBI_15356|http://purl.obolibrary.org/obo/CHEBI_17561 |
T51 | 1368-1377 | Chemical | denotes | disulfide | http://purl.obolibrary.org/obo/CHEBI_48343 |
T52 | 1391-1394 | Chemical | denotes | Cys | http://purl.obolibrary.org/obo/CHEBI_29950|http://purl.obolibrary.org/obo/CHEBI_15356|http://purl.obolibrary.org/obo/CHEBI_17561 |
T55 | 1518-1521 | Chemical | denotes | Cys | http://purl.obolibrary.org/obo/CHEBI_29950|http://purl.obolibrary.org/obo/CHEBI_15356|http://purl.obolibrary.org/obo/CHEBI_17561 |
T58 | 1531-1534 | Chemical | denotes | Val | http://purl.obolibrary.org/obo/CHEBI_16414|http://purl.obolibrary.org/obo/CHEBI_30015 |
T60 | 1573-1576 | Chemical | denotes | Ser | http://purl.obolibrary.org/obo/CHEBI_17115|http://purl.obolibrary.org/obo/CHEBI_29999 |
T62 | 1586-1589 | Chemical | denotes | Gln | http://purl.obolibrary.org/obo/CHEBI_30011 |
T63 | 1650-1660 | Chemical | denotes | methionine | http://purl.obolibrary.org/obo/CHEBI_16811|http://purl.obolibrary.org/obo/CHEBI_64558 |
T65 | 1683-1693 | Chemical | denotes | methionine | http://purl.obolibrary.org/obo/CHEBI_16811|http://purl.obolibrary.org/obo/CHEBI_64558 |
T67 | 1831-1834 | Chemical | denotes | Met | http://purl.obolibrary.org/obo/CHEBI_16044|http://purl.obolibrary.org/obo/CHEBI_16643|http://purl.obolibrary.org/obo/CHEBI_16811 |
T70 | 1856-1867 | Chemical | denotes | amino acids | http://purl.obolibrary.org/obo/CHEBI_33709 |
T71 | 1920-1923 | Chemical | denotes | Ser | http://purl.obolibrary.org/obo/CHEBI_17115|http://purl.obolibrary.org/obo/CHEBI_29999 |
T73 | 1928-1931 | Chemical | denotes | Gln | http://purl.obolibrary.org/obo/CHEBI_30011 |
T74 | 2098-2109 | Chemical | denotes | nucleotides | http://purl.obolibrary.org/obo/CHEBI_36976 |
T75 | 2608-2620 | Chemical | denotes | Glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
T76 | 2771-2778 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T77 | 3028-3031 | Chemical | denotes | SDS | http://purl.obolibrary.org/obo/CHEBI_8984 |
T78 | 3083-3090 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T79 | 3381-3388 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T80 | 3407-3416 | Chemical | denotes | glutamine | http://purl.obolibrary.org/obo/CHEBI_28300 |
T81 | 3440-3448 | Chemical | denotes | N-glycan | http://purl.obolibrary.org/obo/CHEBI_59520 |
T82 | 3650-3658 | Chemical | denotes | cysteine | http://purl.obolibrary.org/obo/CHEBI_15356 |
T83 | 3721-3728 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
T84 | 3776-3783 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
T85 | 3839-3843 | Chemical | denotes | ions | http://purl.obolibrary.org/obo/CHEBI_24870 |
T86 | 3897-3904 | Chemical | denotes | oxonium | http://purl.obolibrary.org/obo/CHEBI_29412 |
T87 | 3905-3909 | Chemical | denotes | ions | http://purl.obolibrary.org/obo/CHEBI_24870 |
T88 | 3933-3940 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
T89 | 3950-3954 | Chemical | denotes | ions | http://purl.obolibrary.org/obo/CHEBI_24870 |
T90 | 4037-4041 | Chemical | denotes | ions | http://purl.obolibrary.org/obo/CHEBI_24870 |
T91 | 4113-4119 | Chemical | denotes | fucose | http://purl.obolibrary.org/obo/CHEBI_33984 |
T92 | 4163-4175 | Chemical | denotes | glycopeptide | http://purl.obolibrary.org/obo/CHEBI_24396 |
LitCovid-sample-PD-NCBITaxon
Id | Subject | Object | Predicate | Lexical cue | ncbi_taxonomy_id |
---|---|---|---|---|---|
T40 | 50-60 | Species | denotes | SARS-CoV-2 | NCBItxid:2697049 |
T41 | 99-104 | Species | denotes | Human | NCBItxid:9606 |
T42 | 154-164 | Species | denotes | SARS-CoV-2 | NCBItxid:2697049 |
T43 | 263-268 | Species | denotes | human | NCBItxid:9606 |
T44 | 2115-2126 | Species | denotes | pseudovirus | NCBItxid:186672 |
T45 | 2151-2161 | Species | denotes | SARS-CoV-2 | NCBItxid:2697049 |
T46 | 2591-2601 | Species | denotes | SARS-CoV-2 | NCBItxid:2697049 |
T47 | 2650-2655 | Species | denotes | Human | NCBItxid:9606 |
T48 | 2678-2688 | Species | denotes | SARS-CoV-2 | NCBItxid:2697049 |
T49 | 2713-2718 | Species | denotes | human | NCBItxid:9606 |
T50 | 3070-3080 | Species | denotes | SARS-CoV-2 | NCBItxid:2697049 |
T51 | 3117-3122 | Species | denotes | human | NCBItxid:9606 |
LitCovid-sample-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T49 | 0-109 | Sentence | denotes | Expression, Purification, and Characterization of SARS-CoV-2 Spike Glycoprotein Trimer and Soluble Human ACE2 |
T50 | 110-616 | Sentence | denotes | A trimer-stabilized, soluble variant of the SARS-CoV-2 S that contains 22 canonical N-linked glycosylation sequons per protomer and a soluble version of human ACE2 that contains six, lacking the most C-terminal seventh, canonical N-linked glycosylation sequons (Figure 1 A) were purified from the media of transfected HEK293 cells, and the quaternary structure confirmed by negative EM staining for the S trimer (Figure 1B) and purity examined by SDS-PAGE Coomassie G-250 stained gels for both (Figure 1C). |
T51 | 617-745 | Sentence | denotes | In addition, proteolytic digestions followed by proteomic analyses confirmed that the proteins were highly purified (Table S12). |
T52 | 746-945 | Sentence | denotes | Finally, the N terminus of both the mature S and the soluble mature ACE2 were empirically determined via proteolytic digestions and liquid chromatography-tandem mass spectrometry (LC-MS/MS) analyses. |
T53 | 946-1174 | Sentence | denotes | These results confirmed that both the secreted, mature forms of S protein and ACE2 begin with an N-terminal glutamine that has undergone condensation to form pyroglutamine at residues 14 and 18, respectively (Figures 1D and S1). |
T54 | 1175-1422 | Sentence | denotes | The N-terminal peptide observed for S also contains a glycan at Asn-0017 (Figure 1D), and mass spectrometry analysis of non-reducing proteolytic digestions confirmed that Cys-0015 of S is in a disulfide linkage with Cys-0136 (Figure S2; Table S2). |
T55 | 1423-1756 | Sentence | denotes | Given that SignalP (Almagro Armenteros et al., 2019) predicts signal sequence cleavage between Cys-0015 and Val-0016 but we observed cleavage between Ser-0013 and Gln-0014, we examined the possibility that an in-frame upstream methionine to the proposed start methionine (Figure 1A) might be used to initiate translation (Figure S3). |
T56 | 1757-1976 | Sentence | denotes | If one examines the predicted signal sequence cleavage using the in-frame Met that is encoded nine amino acids upstream, SignalP now predicts cleavage between the Ser and Gln that we observed in our studies (Figure S3). |
T57 | 1977-2218 | Sentence | denotes | To examine whether this impacted S expression, we expressed constructs that contained or did not contain the upstream 27 nucleotides in a pseudovirus (VSV) system expressing SARS-CoV-2 S (Figure S4) and in our HEK293 system (data not shown). |
T58 | 2219-2340 | Sentence | denotes | Both expression systems produced a similar amount of S regardless of which expression construct was utilized (Figure S4). |
T59 | 2341-2546 | Sentence | denotes | Thus, while the translation initiation start site has still not been fully defined, allowing for earlier translation in expression construct design did not have a significant impact on the generation of S. |
T60 | 2547-2660 | Sentence | denotes | Figure 1 Expression and Characterization of SARS-CoV-2 Spike Glycoprotein Trimer Immunogen and Soluble Human ACE2 |
T61 | 2661-2724 | Sentence | denotes | (A) Sequences of SARS-CoV-2 S immunogen and soluble human ACE2. |
T62 | 2725-2831 | Sentence | denotes | The N-terminal pyroglutamines for both mature protein monomers are bolded, underlined, and shown in green. |
T63 | 2832-2918 | Sentence | denotes | The canonical N-linked glycosylation sequons are bolded, underlined, and shown in red. |
T64 | 2919-3128 | Sentence | denotes | (B and C) Negative stain electron microscopy of the purified trimer (B) and Coomassie G-250-stained reducing SDS-PAGE gels (C) confirmed purity of the SARS-CoV-2 S protein trimer and of the soluble human ACE2. |
T65 | 3129-3159 | Sentence | denotes | MWM, molecular weight markers. |
T66 | 3160-3329 | Sentence | denotes | (D) A representative Step-HCD fragmentation spectrum from mass-spectrometry analysis of a tryptic digest of S annotated manually based on search results from pGlyco 2.2. |
T67 | 3330-3422 | Sentence | denotes | This spectrum defines the N terminus of the mature protein monomer as (pyro-)glutamine 0014. |
T68 | 3423-3584 | Sentence | denotes | A representative N-glycan consistent with this annotation and our glycomics data (Figure 2) is overlaid by using the Symbol Nomenclature For Glycans (SNFG) code. |
T69 | 3585-3621 | Sentence | denotes | This complex glycan occurs at N0017. |
T70 | 3622-3741 | Sentence | denotes | Note, that as expected, the cysteine is carbamidomethylated, and the mass accuracy of the assigned peptide is 0.98 ppm. |
T71 | 3742-3854 | Sentence | denotes | On the sequence of the N-terminal peptide and in the spectrum, the assigned b (blue) and y (red) ions are shown. |
T72 | 3855-4008 | Sentence | denotes | In the spectrum, purple highlights glycan oxonium ions and green marks intact peptide fragment ions with various partial glycan sequences still attached. |
T73 | 4009-4176 | Sentence | denotes | Note that the green-labeled ions allow for limited topology to be extracted including defining that the fucose is on the core and not the antennae of the glycopeptide. |
LitCovid-sample-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T30 | 50-60 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T31 | 154-164 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T32 | 2151-2161 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T33 | 2591-2601 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T34 | 2678-2688 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T35 | 3070-3080 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-sample-UniProt
Id | Subject | Object | Predicate | Lexical cue | uniprot_id |
---|---|---|---|---|---|
T1191 | 61-79 | Protein | denotes | Spike Glycoprotein | https://www.uniprot.org/uniprot/Q9QAS2|https://www.uniprot.org/uniprot/Q9QAR5|https://www.uniprot.org/uniprot/Q9QAQ8|https://www.uniprot.org/uniprot/Q9IW04|https://www.uniprot.org/uniprot/Q9IKD1|https://www.uniprot.org/uniprot/Q990M4|https://www.uniprot.org/uniprot/Q990M3|https://www.uniprot.org/uniprot/Q990M2|https://www.uniprot.org/uniprot/Q990M1|https://www.uniprot.org/uniprot/Q91AV1|https://www.uniprot.org/uniprot/Q91A26|https://www.uniprot.org/uniprot/Q8V436|https://www.uniprot.org/uniprot/Q8JSP8|https://www.uniprot.org/uniprot/Q8BB25|https://www.uniprot.org/uniprot/Q86623|https://www.uniprot.org/uniprot/Q85088|https://www.uniprot.org/uniprot/Q85087|https://www.uniprot.org/uniprot/Q80BV6|https://www.uniprot.org/uniprot/Q7TFB1|https://www.uniprot.org/uniprot/Q7TFA2|https://www.uniprot.org/uniprot/Q7TA19|https://www.uniprot.org/uniprot/Q7T6T3|https://www.uniprot.org/uniprot/Q7T696|https://www.uniprot.org/uniprot/Q77NC4|https://www.uniprot.org/uniprot/Q6TNF9|https://www.uniprot.org/uniprot/Q6R1L7|https://www.uniprot.org/uniprot/Q6QU82|https://www.uniprot.org/uniprot/Q6Q1S2|https://www.uniprot.org/uniprot/Q696Q6|https://www.uniprot.org/uniprot/Q66291|https://www.uniprot.org/uniprot/Q66290|https://www.uniprot.org/uniprot/Q66199|https://www.uniprot.org/uniprot/Q66177|https://www.uniprot.org/uniprot/Q66176|https://www.uniprot.org/uniprot/Q66174|https://www.uniprot.org/uniprot/Q65984|https://www.uniprot.org/uniprot/Q5MQD0|https://www.uniprot.org/uniprot/Q5I5X9|https://www.uniprot.org/uniprot/Q5DIY0|https://www.uniprot.org/uniprot/Q5DIX9|https://www.uniprot.org/uniprot/Q5DIX8|https://www.uniprot.org/uniprot/Q5DIX7|https://www.uniprot.org/uniprot/Q52PA3|https://www.uniprot.org/uniprot/Q4ZJS1|https://www.uniprot.org/uniprot/Q4U5G0|https://www.uniprot.org/uniprot/Q3T8J0|https://www.uniprot.org/uniprot/Q3LZX1|https://www.uniprot.org/uniprot/Q3I5J5|https://www.uniprot.org/uniprot/Q14EB0|https://www.uniprot.org/uniprot/Q0ZME7|https://www.uniprot.org/uniprot/Q0Q4F2|https://www.uniprot.org/uniprot/Q0Q475|https://www.uniprot.org/uniprot/Q0Q466|https://www.uniprot.org/uniprot/Q0GNB8|https://www.uniprot.org/uniprot/Q02385|https://www.uniprot.org/uniprot/Q02167|https://www.uniprot.org/uniprot/Q01977|https://www.uniprot.org/uniprot/Q008X4|https://www.uniprot.org/uniprot/P89344|https://www.uniprot.org/uniprot/P89343|https://www.uniprot.org/uniprot/P89342|https://www.uniprot.org/uniprot/P59594|https://www.uniprot.org/uniprot/P36334|https://www.uniprot.org/uniprot/P36300|https://www.uniprot.org/uniprot/P33470|https://www.uniprot.org/uniprot/P30208|https://www.uniprot.org/uniprot/P30207|https://www.uniprot.org/uniprot/P30206|https://www.uniprot.org/uniprot/P27662|https://www.uniprot.org/uniprot/P27655|https://www.uniprot.org/uniprot/P27277|https://www.uniprot.org/uniprot/P25194|https://www.uniprot.org/uniprot/P25193|https://www.uniprot.org/uniprot/P25192|https://www.uniprot.org/uniprot/P25191|https://www.uniprot.org/uniprot/P25190|https://www.uniprot.org/uniprot/P24413|https://www.uniprot.org/uniprot/P23052|https://www.uniprot.org/uniprot/P22432|https://www.uniprot.org/uniprot/P18450|https://www.uniprot.org/uniprot/P17662|https://www.uniprot.org/uniprot/P15777|https://www.uniprot.org/uniprot/P15423|https://www.uniprot.org/uniprot/P12722|https://www.uniprot.org/uniprot/P12651|https://www.uniprot.org/uniprot/P12650|https://www.uniprot.org/uniprot/P12647|https://www.uniprot.org/uniprot/P11225|https://www.uniprot.org/uniprot/P11224|https://www.uniprot.org/uniprot/P11223|https://www.uniprot.org/uniprot/P10033|https://www.uniprot.org/uniprot/P0DTC2|https://www.uniprot.org/uniprot/P07946|https://www.uniprot.org/uniprot/P05135|https://www.uniprot.org/uniprot/P05134|https://www.uniprot.org/uniprot/O90304|https://www.uniprot.org/uniprot/O39227|https://www.uniprot.org/uniprot/K9N5Q8|https://www.uniprot.org/uniprot/A3EXG6|https://www.uniprot.org/uniprot/A3EXD0|https://www.uniprot.org/uniprot/A3EX94 |
T1292 | 67-79 | Protein | denotes | Glycoprotein | https://www.uniprot.org/uniprot/Q82706|https://www.uniprot.org/uniprot/Q82683|https://www.uniprot.org/uniprot/Q82020|https://www.uniprot.org/uniprot/Q787B5|https://www.uniprot.org/uniprot/Q77SK0|https://www.uniprot.org/uniprot/Q77N36|https://www.uniprot.org/uniprot/Q76G52|https://www.uniprot.org/uniprot/Q75T09|https://www.uniprot.org/uniprot/Q6X1D5|https://www.uniprot.org/uniprot/Q6X1D1|https://www.uniprot.org/uniprot/Q6TYA0|https://www.uniprot.org/uniprot/Q6E0W7|https://www.uniprot.org/uniprot/Q66T62|https://www.uniprot.org/uniprot/Q5VKP3|https://www.uniprot.org/uniprot/Q5VKN9|https://www.uniprot.org/uniprot/Q5K2K4|https://www.uniprot.org/uniprot/Q5IX93|https://www.uniprot.org/uniprot/Q5IX92|https://www.uniprot.org/uniprot/Q5IX91|https://www.uniprot.org/uniprot/Q5IX90|https://www.uniprot.org/uniprot/Q5IX89|https://www.uniprot.org/uniprot/Q5IX88|https://www.uniprot.org/uniprot/Q5IX87|https://www.uniprot.org/uniprot/Q5GA86|https://www.uniprot.org/uniprot/Q58FH1|https://www.uniprot.org/uniprot/Q4VKV3|https://www.uniprot.org/uniprot/Q4F900|https://www.uniprot.org/uniprot/Q49LL3|https://www.uniprot.org/uniprot/Q49IU2|https://www.uniprot.org/uniprot/Q49IU1|https://www.uniprot.org/uniprot/Q49IT9|https://www.uniprot.org/uniprot/Q49IT8|https://www.uniprot.org/uniprot/Q49AV0|https://www.uniprot.org/uniprot/Q0GBY1|https://www.uniprot.org/uniprot/Q0GBX6|https://www.uniprot.org/uniprot/Q08089|https://www.uniprot.org/uniprot/P32595|https://www.uniprot.org/uniprot/P32550|https://www.uniprot.org/uniprot/P19462|https://www.uniprot.org/uniprot/P16288|https://www.uniprot.org/uniprot/P15199|https://www.uniprot.org/uniprot/P13180|https://www.uniprot.org/uniprot/P0C572|https://www.uniprot.org/uniprot/P08667|https://www.uniprot.org/uniprot/P08163|https://www.uniprot.org/uniprot/P07923|https://www.uniprot.org/uniprot/P04884|https://www.uniprot.org/uniprot/P04883|https://www.uniprot.org/uniprot/P04882|https://www.uniprot.org/uniprot/P03524|https://www.uniprot.org/uniprot/P03522|https://www.uniprot.org/uniprot/O92284|https://www.uniprot.org/uniprot/O56677|https://www.uniprot.org/uniprot/O10236|https://www.uniprot.org/uniprot/J7HBH4|https://www.uniprot.org/uniprot/D8V075|https://www.uniprot.org/uniprot/A7WNB3|https://www.uniprot.org/uniprot/A4UHQ6|https://www.uniprot.org/uniprot/A4UHQ1|https://www.uniprot.org/uniprot/A3RM22|https://www.uniprot.org/uniprot/A3F5R8|https://www.uniprot.org/uniprot/A3F5R3|https://www.uniprot.org/uniprot/A3F5Q8|https://www.uniprot.org/uniprot/A3F5N3|https://www.uniprot.org/uniprot/A3F5M3|https://www.uniprot.org/uniprot/A3F5L8 |
T1358 | 105-109 | Protein | denotes | ACE2 | https://www.uniprot.org/uniprot/Q9UFZ6 |
T1359 | 269-273 | Protein | denotes | ACE2 | https://www.uniprot.org/uniprot/Q9UFZ6 |
T1360 | 740-743 | Protein | denotes | S12 | https://www.uniprot.org/uniprot/Q4VAY7|https://www.uniprot.org/uniprot/P28222 |
T1362 | 814-818 | Protein | denotes | ACE2 | https://www.uniprot.org/uniprot/Q9UFZ6 |
T1363 | 1010-1019 | Protein | denotes | S protein | https://www.uniprot.org/uniprot/Q9UIP0|https://www.uniprot.org/uniprot/Q9UIN9|https://www.uniprot.org/uniprot/Q9UIN8|https://www.uniprot.org/uniprot/Q9UIN7|https://www.uniprot.org/uniprot/Q9UIN6|https://www.uniprot.org/uniprot/Q9UBH8|https://www.uniprot.org/uniprot/Q9NRH8|https://www.uniprot.org/uniprot/Q9NRH7|https://www.uniprot.org/uniprot/Q9NRH6|https://www.uniprot.org/uniprot/Q9NRH5|https://www.uniprot.org/uniprot/Q9NRH4|https://www.uniprot.org/uniprot/Q9NPG5|https://www.uniprot.org/uniprot/Q9NPE0|https://www.uniprot.org/uniprot/Q9NP52|https://www.uniprot.org/uniprot/Q95IF9|https://www.uniprot.org/uniprot/Q8N5P3|https://www.uniprot.org/uniprot/Q8IZU6|https://www.uniprot.org/uniprot/Q8IZU5|https://www.uniprot.org/uniprot/Q8IZU4|https://www.uniprot.org/uniprot/Q86Z04|https://www.uniprot.org/uniprot/Q7YR44|https://www.uniprot.org/uniprot/Q7LA71|https://www.uniprot.org/uniprot/Q7LA70|https://www.uniprot.org/uniprot/Q5STD2|https://www.uniprot.org/uniprot/Q5SQ85|https://www.uniprot.org/uniprot/Q1XI16|https://www.uniprot.org/uniprot/Q1XI12|https://www.uniprot.org/uniprot/Q15517|https://www.uniprot.org/uniprot/O43509|https://www.uniprot.org/uniprot/O19084|https://www.uniprot.org/uniprot/B0UYZ7|https://www.uniprot.org/uniprot/B0S7V2|https://www.uniprot.org/uniprot/A5A6L9 |
T1396 | 1024-1028 | Protein | denotes | ACE2 | https://www.uniprot.org/uniprot/Q9UFZ6 |
T1397 | 1179-1197 | Protein | denotes | N-terminal peptide | https://www.uniprot.org/uniprot/Q9DB14|https://www.uniprot.org/uniprot/Q9D2P6|https://www.uniprot.org/uniprot/Q9CYP0|https://www.uniprot.org/uniprot/Q9BS38|https://www.uniprot.org/uniprot/Q8CCZ3|https://www.uniprot.org/uniprot/Q6FHD0|https://www.uniprot.org/uniprot/Q06A28|https://www.uniprot.org/uniprot/P27682|https://www.uniprot.org/uniprot/P18844|https://www.uniprot.org/uniprot/P12961|https://www.uniprot.org/uniprot/P05408|https://www.uniprot.org/uniprot/P01165|https://www.uniprot.org/uniprot/P01164|https://www.uniprot.org/uniprot/A5HAK0|https://www.uniprot.org/uniprot/A5A6J6 |
T1412 | 2602-2620 | Protein | denotes | Spike Glycoprotein | https://www.uniprot.org/uniprot/Q9QAS2|https://www.uniprot.org/uniprot/Q9QAR5|https://www.uniprot.org/uniprot/Q9QAQ8|https://www.uniprot.org/uniprot/Q9IW04|https://www.uniprot.org/uniprot/Q9IKD1|https://www.uniprot.org/uniprot/Q990M4|https://www.uniprot.org/uniprot/Q990M3|https://www.uniprot.org/uniprot/Q990M2|https://www.uniprot.org/uniprot/Q990M1|https://www.uniprot.org/uniprot/Q91AV1|https://www.uniprot.org/uniprot/Q91A26|https://www.uniprot.org/uniprot/Q8V436|https://www.uniprot.org/uniprot/Q8JSP8|https://www.uniprot.org/uniprot/Q8BB25|https://www.uniprot.org/uniprot/Q86623|https://www.uniprot.org/uniprot/Q85088|https://www.uniprot.org/uniprot/Q85087|https://www.uniprot.org/uniprot/Q80BV6|https://www.uniprot.org/uniprot/Q7TFB1|https://www.uniprot.org/uniprot/Q7TFA2|https://www.uniprot.org/uniprot/Q7TA19|https://www.uniprot.org/uniprot/Q7T6T3|https://www.uniprot.org/uniprot/Q7T696|https://www.uniprot.org/uniprot/Q77NC4|https://www.uniprot.org/uniprot/Q6TNF9|https://www.uniprot.org/uniprot/Q6R1L7|https://www.uniprot.org/uniprot/Q6QU82|https://www.uniprot.org/uniprot/Q6Q1S2|https://www.uniprot.org/uniprot/Q696Q6|https://www.uniprot.org/uniprot/Q66291|https://www.uniprot.org/uniprot/Q66290|https://www.uniprot.org/uniprot/Q66199|https://www.uniprot.org/uniprot/Q66177|https://www.uniprot.org/uniprot/Q66176|https://www.uniprot.org/uniprot/Q66174|https://www.uniprot.org/uniprot/Q65984|https://www.uniprot.org/uniprot/Q5MQD0|https://www.uniprot.org/uniprot/Q5I5X9|https://www.uniprot.org/uniprot/Q5DIY0|https://www.uniprot.org/uniprot/Q5DIX9|https://www.uniprot.org/uniprot/Q5DIX8|https://www.uniprot.org/uniprot/Q5DIX7|https://www.uniprot.org/uniprot/Q52PA3|https://www.uniprot.org/uniprot/Q4ZJS1|https://www.uniprot.org/uniprot/Q4U5G0|https://www.uniprot.org/uniprot/Q3T8J0|https://www.uniprot.org/uniprot/Q3LZX1|https://www.uniprot.org/uniprot/Q3I5J5|https://www.uniprot.org/uniprot/Q14EB0|https://www.uniprot.org/uniprot/Q0ZME7|https://www.uniprot.org/uniprot/Q0Q4F2|https://www.uniprot.org/uniprot/Q0Q475|https://www.uniprot.org/uniprot/Q0Q466|https://www.uniprot.org/uniprot/Q0GNB8|https://www.uniprot.org/uniprot/Q02385|https://www.uniprot.org/uniprot/Q02167|https://www.uniprot.org/uniprot/Q01977|https://www.uniprot.org/uniprot/Q008X4|https://www.uniprot.org/uniprot/P89344|https://www.uniprot.org/uniprot/P89343|https://www.uniprot.org/uniprot/P89342|https://www.uniprot.org/uniprot/P59594|https://www.uniprot.org/uniprot/P36334|https://www.uniprot.org/uniprot/P36300|https://www.uniprot.org/uniprot/P33470|https://www.uniprot.org/uniprot/P30208|https://www.uniprot.org/uniprot/P30207|https://www.uniprot.org/uniprot/P30206|https://www.uniprot.org/uniprot/P27662|https://www.uniprot.org/uniprot/P27655|https://www.uniprot.org/uniprot/P27277|https://www.uniprot.org/uniprot/P25194|https://www.uniprot.org/uniprot/P25193|https://www.uniprot.org/uniprot/P25192|https://www.uniprot.org/uniprot/P25191|https://www.uniprot.org/uniprot/P25190|https://www.uniprot.org/uniprot/P24413|https://www.uniprot.org/uniprot/P23052|https://www.uniprot.org/uniprot/P22432|https://www.uniprot.org/uniprot/P18450|https://www.uniprot.org/uniprot/P17662|https://www.uniprot.org/uniprot/P15777|https://www.uniprot.org/uniprot/P15423|https://www.uniprot.org/uniprot/P12722|https://www.uniprot.org/uniprot/P12651|https://www.uniprot.org/uniprot/P12650|https://www.uniprot.org/uniprot/P12647|https://www.uniprot.org/uniprot/P11225|https://www.uniprot.org/uniprot/P11224|https://www.uniprot.org/uniprot/P11223|https://www.uniprot.org/uniprot/P10033|https://www.uniprot.org/uniprot/P0DTC2|https://www.uniprot.org/uniprot/P07946|https://www.uniprot.org/uniprot/P05135|https://www.uniprot.org/uniprot/P05134|https://www.uniprot.org/uniprot/O90304|https://www.uniprot.org/uniprot/O39227|https://www.uniprot.org/uniprot/K9N5Q8|https://www.uniprot.org/uniprot/A3EXG6|https://www.uniprot.org/uniprot/A3EXD0|https://www.uniprot.org/uniprot/A3EX94 |
T1513 | 2608-2620 | Protein | denotes | Glycoprotein | https://www.uniprot.org/uniprot/Q82706|https://www.uniprot.org/uniprot/Q82683|https://www.uniprot.org/uniprot/Q82020|https://www.uniprot.org/uniprot/Q787B5|https://www.uniprot.org/uniprot/Q77SK0|https://www.uniprot.org/uniprot/Q77N36|https://www.uniprot.org/uniprot/Q76G52|https://www.uniprot.org/uniprot/Q75T09|https://www.uniprot.org/uniprot/Q6X1D5|https://www.uniprot.org/uniprot/Q6X1D1|https://www.uniprot.org/uniprot/Q6TYA0|https://www.uniprot.org/uniprot/Q6E0W7|https://www.uniprot.org/uniprot/Q66T62|https://www.uniprot.org/uniprot/Q5VKP3|https://www.uniprot.org/uniprot/Q5VKN9|https://www.uniprot.org/uniprot/Q5K2K4|https://www.uniprot.org/uniprot/Q5IX93|https://www.uniprot.org/uniprot/Q5IX92|https://www.uniprot.org/uniprot/Q5IX91|https://www.uniprot.org/uniprot/Q5IX90|https://www.uniprot.org/uniprot/Q5IX89|https://www.uniprot.org/uniprot/Q5IX88|https://www.uniprot.org/uniprot/Q5IX87|https://www.uniprot.org/uniprot/Q5GA86|https://www.uniprot.org/uniprot/Q58FH1|https://www.uniprot.org/uniprot/Q4VKV3|https://www.uniprot.org/uniprot/Q4F900|https://www.uniprot.org/uniprot/Q49LL3|https://www.uniprot.org/uniprot/Q49IU2|https://www.uniprot.org/uniprot/Q49IU1|https://www.uniprot.org/uniprot/Q49IT9|https://www.uniprot.org/uniprot/Q49IT8|https://www.uniprot.org/uniprot/Q49AV0|https://www.uniprot.org/uniprot/Q0GBY1|https://www.uniprot.org/uniprot/Q0GBX6|https://www.uniprot.org/uniprot/Q08089|https://www.uniprot.org/uniprot/P32595|https://www.uniprot.org/uniprot/P32550|https://www.uniprot.org/uniprot/P19462|https://www.uniprot.org/uniprot/P16288|https://www.uniprot.org/uniprot/P15199|https://www.uniprot.org/uniprot/P13180|https://www.uniprot.org/uniprot/P0C572|https://www.uniprot.org/uniprot/P08667|https://www.uniprot.org/uniprot/P08163|https://www.uniprot.org/uniprot/P07923|https://www.uniprot.org/uniprot/P04884|https://www.uniprot.org/uniprot/P04883|https://www.uniprot.org/uniprot/P04882|https://www.uniprot.org/uniprot/P03524|https://www.uniprot.org/uniprot/P03522|https://www.uniprot.org/uniprot/O92284|https://www.uniprot.org/uniprot/O56677|https://www.uniprot.org/uniprot/O10236|https://www.uniprot.org/uniprot/J7HBH4|https://www.uniprot.org/uniprot/D8V075|https://www.uniprot.org/uniprot/A7WNB3|https://www.uniprot.org/uniprot/A4UHQ6|https://www.uniprot.org/uniprot/A4UHQ1|https://www.uniprot.org/uniprot/A3RM22|https://www.uniprot.org/uniprot/A3F5R8|https://www.uniprot.org/uniprot/A3F5R3|https://www.uniprot.org/uniprot/A3F5Q8|https://www.uniprot.org/uniprot/A3F5N3|https://www.uniprot.org/uniprot/A3F5M3|https://www.uniprot.org/uniprot/A3F5L8 |
T1579 | 2656-2660 | Protein | denotes | ACE2 | https://www.uniprot.org/uniprot/Q9UFZ6 |
T1580 | 2719-2723 | Protein | denotes | ACE2 | https://www.uniprot.org/uniprot/Q9UFZ6 |
T1581 | 3081-3090 | Protein | denotes | S protein | https://www.uniprot.org/uniprot/Q9UIP0|https://www.uniprot.org/uniprot/Q9UIN9|https://www.uniprot.org/uniprot/Q9UIN8|https://www.uniprot.org/uniprot/Q9UIN7|https://www.uniprot.org/uniprot/Q9UIN6|https://www.uniprot.org/uniprot/Q9UBH8|https://www.uniprot.org/uniprot/Q9NRH8|https://www.uniprot.org/uniprot/Q9NRH7|https://www.uniprot.org/uniprot/Q9NRH6|https://www.uniprot.org/uniprot/Q9NRH5|https://www.uniprot.org/uniprot/Q9NRH4|https://www.uniprot.org/uniprot/Q9NPG5|https://www.uniprot.org/uniprot/Q9NPE0|https://www.uniprot.org/uniprot/Q9NP52|https://www.uniprot.org/uniprot/Q95IF9|https://www.uniprot.org/uniprot/Q8N5P3|https://www.uniprot.org/uniprot/Q8IZU6|https://www.uniprot.org/uniprot/Q8IZU5|https://www.uniprot.org/uniprot/Q8IZU4|https://www.uniprot.org/uniprot/Q86Z04|https://www.uniprot.org/uniprot/Q7YR44|https://www.uniprot.org/uniprot/Q7LA71|https://www.uniprot.org/uniprot/Q7LA70|https://www.uniprot.org/uniprot/Q5STD2|https://www.uniprot.org/uniprot/Q5SQ85|https://www.uniprot.org/uniprot/Q1XI16|https://www.uniprot.org/uniprot/Q1XI12|https://www.uniprot.org/uniprot/Q15517|https://www.uniprot.org/uniprot/O43509|https://www.uniprot.org/uniprot/O19084|https://www.uniprot.org/uniprot/B0UYZ7|https://www.uniprot.org/uniprot/B0S7V2|https://www.uniprot.org/uniprot/A5A6L9 |
T1614 | 3123-3127 | Protein | denotes | ACE2 | https://www.uniprot.org/uniprot/Q9UFZ6 |
T1615 | 3765-3783 | Protein | denotes | N-terminal peptide | https://www.uniprot.org/uniprot/Q9DB14|https://www.uniprot.org/uniprot/Q9D2P6|https://www.uniprot.org/uniprot/Q9CYP0|https://www.uniprot.org/uniprot/Q9BS38|https://www.uniprot.org/uniprot/Q8CCZ3|https://www.uniprot.org/uniprot/Q6FHD0|https://www.uniprot.org/uniprot/Q06A28|https://www.uniprot.org/uniprot/P27682|https://www.uniprot.org/uniprot/P18844|https://www.uniprot.org/uniprot/P12961|https://www.uniprot.org/uniprot/P05408|https://www.uniprot.org/uniprot/P01165|https://www.uniprot.org/uniprot/P01164|https://www.uniprot.org/uniprot/A5HAK0|https://www.uniprot.org/uniprot/A5A6J6 |
LitCovid-sample-PD-IDO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T45 | 435-440 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cells |
T46 | 2386-2390 | http://purl.obolibrary.org/obo/BFO_0000029 | denotes | site |
LitCovid-sample-PD-FMA
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T46 | 67-79 | Body_part | denotes | Glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
T47 | 435-440 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T48 | 703-711 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T49 | 1012-1019 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T50 | 1054-1063 | Body_part | denotes | glutamine | http://purl.org/sig/ont/fma/fma82752 |
T51 | 1650-1660 | Body_part | denotes | methionine | http://purl.org/sig/ont/fma/fma82759 |
T52 | 1683-1693 | Body_part | denotes | methionine | http://purl.org/sig/ont/fma/fma82759 |
T53 | 1856-1867 | Body_part | denotes | amino acids | http://purl.org/sig/ont/fma/fma82739 |
T54 | 2098-2109 | Body_part | denotes | nucleotides | http://purl.org/sig/ont/fma/fma82740 |
T55 | 2608-2620 | Body_part | denotes | Glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
T56 | 2771-2778 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T57 | 3083-3090 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T58 | 3381-3388 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T59 | 3407-3416 | Body_part | denotes | glutamine | http://purl.org/sig/ont/fma/fma82752 |
T60 | 3650-3658 | Body_part | denotes | cysteine | http://purl.org/sig/ont/fma/fma82751 |
T61 | 4113-4119 | Body_part | denotes | fucose | http://purl.org/sig/ont/fma/fma82790 |
T62 | 4163-4175 | Body_part | denotes | glycopeptide | http://purl.org/sig/ont/fma/fma82784 |
LitCovid-sample-PD-MAT
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2 | 4147-4155 | http://purl.obolibrary.org/obo/MAT_0000086 | denotes | antennae |
LitCovid-sample-PD-GO-BP-0
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T32 | 203-216 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
T33 | 349-362 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
T34 | 642-652 | http://purl.obolibrary.org/obo/GO_0007586 | denotes | digestions |
T35 | 863-873 | http://purl.obolibrary.org/obo/GO_0007586 | denotes | digestions |
T36 | 1320-1330 | http://purl.obolibrary.org/obo/GO_0007586 | denotes | digestions |
T37 | 1732-1743 | http://purl.obolibrary.org/obo/GO_0006412 | denotes | translation |
T38 | 2357-2379 | http://purl.obolibrary.org/obo/GO_0006413 | denotes | translation initiation |
T39 | 2357-2368 | http://purl.obolibrary.org/obo/GO_0006412 | denotes | translation |
T40 | 2446-2457 | http://purl.obolibrary.org/obo/GO_0006412 | denotes | translation |
T41 | 2855-2868 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
LitCovid-sample-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T30 | 203-216 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
T31 | 349-362 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
T32 | 642-652 | http://purl.obolibrary.org/obo/GO_0007586 | denotes | digestions |
T33 | 863-873 | http://purl.obolibrary.org/obo/GO_0007586 | denotes | digestions |
T34 | 1320-1330 | http://purl.obolibrary.org/obo/GO_0007586 | denotes | digestions |
T35 | 1732-1743 | http://purl.obolibrary.org/obo/GO_0006412 | denotes | translation |
T36 | 2357-2379 | http://purl.obolibrary.org/obo/GO_0006413 | denotes | translation initiation |
T37 | 2357-2368 | http://purl.obolibrary.org/obo/GO_0006412 | denotes | translation |
T38 | 2446-2457 | http://purl.obolibrary.org/obo/GO_0006412 | denotes | translation |
T39 | 2855-2868 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32841605-30778233-19659502 | 1470-1474 | 30778233 | denotes | 2019 |