PMC:7443692 / 6177-6539 JSONTXT

{"project":"LitCovid-sample-MedDRA","denotations":[{"id":"T7","span":{"begin":184,"end":207},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"},{"id":"T8","span":{"begin":316,"end":321},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"}],"attributes":[{"id":"A7","pred":"meddra_id","subj":"T7","obj":"http://purl.bioontology.org/ontology/MEDDRA/10058063"},{"id":"A8","pred":"meddra_id","subj":"T8","obj":"http://purl.bioontology.org/ontology/MEDDRA/10038555"}],"text":"tps://www.biorxiv.org/content/10.1101/2020.06.30.178897v1). Thus, understanding the glycosylation of the viral Spike trimer is fundamental for the development of efficacious vaccines, neutralizing antibodies, and therapeutic inhibitors of infection.\nACE2 is an integral membrane metalloproteinase that regulates the renin-angiotensin system (Tikellis et al., 201"}

{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T27","span":{"begin":322,"end":333},"obj":"Chemical"}],"attributes":[{"id":"A27","pred":"chebi_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"}],"text":"tps://www.biorxiv.org/content/10.1101/2020.06.30.178897v1). Thus, understanding the glycosylation of the viral Spike trimer is fundamental for the development of efficacious vaccines, neutralizing antibodies, and therapeutic inhibitors of infection.\nACE2 is an integral membrane metalloproteinase that regulates the renin-angiotensin system (Tikellis et al., 201"}

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T33","span":{"begin":60,"end":249},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"tps://www.biorxiv.org/content/10.1101/2020.06.30.178897v1). Thus, understanding the glycosylation of the viral Spike trimer is fundamental for the development of efficacious vaccines, neutralizing antibodies, and therapeutic inhibitors of infection.\nACE2 is an integral membrane metalloproteinase that regulates the renin-angiotensin system (Tikellis et al., 201"}

{"project":"LitCovid-sample-PD-UBERON","denotations":[{"id":"T1","span":{"begin":316,"end":340},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0018229"}],"text":"tps://www.biorxiv.org/content/10.1101/2020.06.30.178897v1). Thus, understanding the glycosylation of the viral Spike trimer is fundamental for the development of efficacious vaccines, neutralizing antibodies, and therapeutic inhibitors of infection.\nACE2 is an integral membrane metalloproteinase that regulates the renin-angiotensin system (Tikellis et al., 201"}

{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T22","span":{"begin":239,"end":248},"obj":"Disease"}],"attributes":[{"id":"A22","pred":"mondo_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"tps://www.biorxiv.org/content/10.1101/2020.06.30.178897v1). Thus, understanding the glycosylation of the viral Spike trimer is fundamental for the development of efficacious vaccines, neutralizing antibodies, and therapeutic inhibitors of infection.\nACE2 is an integral membrane metalloproteinase that regulates the renin-angiotensin system (Tikellis et al., 201"}

{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T699","span":{"begin":250,"end":254},"obj":"Protein"},{"id":"T700","span":{"begin":316,"end":321},"obj":"Protein"},{"id":"T711","span":{"begin":322,"end":333},"obj":"Protein"}],"attributes":[{"id":"A699","pred":"uniprot_id","subj":"T699","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A700","pred":"uniprot_id","subj":"T700","obj":"https://www.uniprot.org/uniprot/Q9TSZ1"},{"id":"A701","pred":"uniprot_id","subj":"T700","obj":"https://www.uniprot.org/uniprot/Q6T5C2"},{"id":"A702","pred":"uniprot_id","subj":"T700","obj":"https://www.uniprot.org/uniprot/Q6FI38"},{"id":"A703","pred":"uniprot_id","subj":"T700","obj":"https://www.uniprot.org/uniprot/Q6DYE7"},{"id":"A704","pred":"uniprot_id","subj":"T700","obj":"https://www.uniprot.org/uniprot/Q6DLW5"},{"id":"A705","pred":"uniprot_id","subj":"T700","obj":"https://www.uniprot.org/uniprot/Q6DLS0"},{"id":"A706","pred":"uniprot_id","subj":"T700","obj":"https://www.uniprot.org/uniprot/Q63497"},{"id":"A707","pred":"uniprot_id","subj":"T700","obj":"https://www.uniprot.org/uniprot/P60016"},{"id":"A708","pred":"uniprot_id","subj":"T700","obj":"https://www.uniprot.org/uniprot/P52115"},{"id":"A709","pred":"uniprot_id","subj":"T700","obj":"https://www.uniprot.org/uniprot/P08424"},{"id":"A710","pred":"uniprot_id","subj":"T700","obj":"https://www.uniprot.org/uniprot/P00797"},{"id":"A711","pred":"uniprot_id","subj":"T711","obj":"https://www.uniprot.org/uniprot/Q10757"}],"text":"tps://www.biorxiv.org/content/10.1101/2020.06.30.178897v1). Thus, understanding the glycosylation of the viral Spike trimer is fundamental for the development of efficacious vaccines, neutralizing antibodies, and therapeutic inhibitors of infection.\nACE2 is an integral membrane metalloproteinase that regulates the renin-angiotensin system (Tikellis et al., 201"}

{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T32","span":{"begin":239,"end":248},"obj":"http://purl.obolibrary.org/obo/IDO_0000586"}],"text":"tps://www.biorxiv.org/content/10.1101/2020.06.30.178897v1). Thus, understanding the glycosylation of the viral Spike trimer is fundamental for the development of efficacious vaccines, neutralizing antibodies, and therapeutic inhibitors of infection.\nACE2 is an integral membrane metalloproteinase that regulates the renin-angiotensin system (Tikellis et al., 201"}

{"project":"LitCovid-sample-PD-GO-BP-0","denotations":[{"id":"T21","span":{"begin":84,"end":97},"obj":"http://purl.obolibrary.org/obo/GO_0070085"}],"text":"tps://www.biorxiv.org/content/10.1101/2020.06.30.178897v1). Thus, understanding the glycosylation of the viral Spike trimer is fundamental for the development of efficacious vaccines, neutralizing antibodies, and therapeutic inhibitors of infection.\nACE2 is an integral membrane metalloproteinase that regulates the renin-angiotensin system (Tikellis et al., 201"}

{"project":"LitCovid-sample-GO-BP","denotations":[{"id":"T19","span":{"begin":84,"end":97},"obj":"http://purl.obolibrary.org/obo/GO_0070085"}],"text":"tps://www.biorxiv.org/content/10.1101/2020.06.30.178897v1). Thus, understanding the glycosylation of the viral Spike trimer is fundamental for the development of efficacious vaccines, neutralizing antibodies, and therapeutic inhibitors of infection.\nACE2 is an integral membrane metalloproteinase that regulates the renin-angiotensin system (Tikellis et al., 201"}