PMC:7443692 / 3597-3977 JSONTXT

{"project":"LitCovid-sample-MedDRA","denotations":[{"id":"T3","span":{"begin":202,"end":225},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"}],"attributes":[{"id":"A3","pred":"meddra_id","subj":"T3","obj":"http://purl.bioontology.org/ontology/MEDDRA/10058063"}],"text":"Given the importance of viral Spike proteins for targeting and entry into host cells along with their location on the viral surface, Spike proteins are often used as immunogens for vaccines to generate neutralizing antibodies and frequently targeted for inhibition by small molecules that might block host receptor binding and/or membrane fusion (Li, 2016; Watanabe et al., 2019)."}

{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T17","span":{"begin":36,"end":44},"obj":"Chemical"},{"id":"T18","span":{"begin":139,"end":147},"obj":"Chemical"}],"attributes":[{"id":"A17","pred":"chebi_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A18","pred":"chebi_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"Given the importance of viral Spike proteins for targeting and entry into host cells along with their location on the viral surface, Spike proteins are often used as immunogens for vaccines to generate neutralizing antibodies and frequently targeted for inhibition by small molecules that might block host receptor binding and/or membrane fusion (Li, 2016; Watanabe et al., 2019)."}

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T24","span":{"begin":0,"end":380},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Given the importance of viral Spike proteins for targeting and entry into host cells along with their location on the viral surface, Spike proteins are often used as immunogens for vaccines to generate neutralizing antibodies and frequently targeted for inhibition by small molecules that might block host receptor binding and/or membrane fusion (Li, 2016; Watanabe et al., 2019)."}

{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T401","span":{"begin":30,"end":44},"obj":"Protein"},{"id":"T402","span":{"begin":133,"end":147},"obj":"Protein"}],"attributes":[{"id":"A401","pred":"uniprot_id","subj":"T401","obj":"https://www.uniprot.org/uniprot/P31340"},{"id":"A402","pred":"uniprot_id","subj":"T402","obj":"https://www.uniprot.org/uniprot/P31340"}],"text":"Given the importance of viral Spike proteins for targeting and entry into host cells along with their location on the viral surface, Spike proteins are often used as immunogens for vaccines to generate neutralizing antibodies and frequently targeted for inhibition by small molecules that might block host receptor binding and/or membrane fusion (Li, 2016; Watanabe et al., 2019)."}

{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T22","span":{"begin":63,"end":78},"obj":"http://purl.obolibrary.org/obo/GO_0044409"},{"id":"T23","span":{"begin":74,"end":78},"obj":"http://purl.obolibrary.org/obo/IDO_0000531"},{"id":"T24","span":{"begin":79,"end":84},"obj":"http://purl.obolibrary.org/obo/CL_0000000"},{"id":"T25","span":{"begin":301,"end":305},"obj":"http://purl.obolibrary.org/obo/IDO_0000531"}],"text":"Given the importance of viral Spike proteins for targeting and entry into host cells along with their location on the viral surface, Spike proteins are often used as immunogens for vaccines to generate neutralizing antibodies and frequently targeted for inhibition by small molecules that might block host receptor binding and/or membrane fusion (Li, 2016; Watanabe et al., 2019)."}

{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T18","span":{"begin":36,"end":44},"obj":"Body_part"},{"id":"T19","span":{"begin":79,"end":84},"obj":"Body_part"},{"id":"T20","span":{"begin":139,"end":147},"obj":"Body_part"}],"attributes":[{"id":"A18","pred":"fma_id","subj":"T18","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A19","pred":"fma_id","subj":"T19","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A20","pred":"fma_id","subj":"T20","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"Given the importance of viral Spike proteins for targeting and entry into host cells along with their location on the viral surface, Spike proteins are often used as immunogens for vaccines to generate neutralizing antibodies and frequently targeted for inhibition by small molecules that might block host receptor binding and/or membrane fusion (Li, 2016; Watanabe et al., 2019)."}

{"project":"LitCovid-sample-PD-GO-BP-0","denotations":[{"id":"T9","span":{"begin":63,"end":84},"obj":"http://purl.obolibrary.org/obo/GO_0030260"},{"id":"T10","span":{"begin":63,"end":78},"obj":"http://purl.obolibrary.org/obo/GO_0044409"},{"id":"T11","span":{"begin":330,"end":345},"obj":"http://purl.obolibrary.org/obo/GO_0061025"}],"text":"Given the importance of viral Spike proteins for targeting and entry into host cells along with their location on the viral surface, Spike proteins are often used as immunogens for vaccines to generate neutralizing antibodies and frequently targeted for inhibition by small molecules that might block host receptor binding and/or membrane fusion (Li, 2016; Watanabe et al., 2019)."}

{"project":"LitCovid-sample-GO-BP","denotations":[{"id":"T8","span":{"begin":36,"end":58},"obj":"http://purl.obolibrary.org/obo/GO_0006605"},{"id":"T9","span":{"begin":63,"end":78},"obj":"http://purl.obolibrary.org/obo/GO_0044409"},{"id":"T10","span":{"begin":330,"end":345},"obj":"http://purl.obolibrary.org/obo/GO_0061025"}],"text":"Given the importance of viral Spike proteins for targeting and entry into host cells along with their location on the viral surface, Spike proteins are often used as immunogens for vaccines to generate neutralizing antibodies and frequently targeted for inhibition by small molecules that might block host receptor binding and/or membrane fusion (Li, 2016; Watanabe et al., 2019)."}

{"project":"2_test","denotations":[{"id":"32841605-27578435-19659469","span":{"begin":351,"end":355},"obj":"27578435"},{"id":"32841605-31121217-19659470","span":{"begin":374,"end":378},"obj":"31121217"}],"text":"Given the importance of viral Spike proteins for targeting and entry into host cells along with their location on the viral surface, Spike proteins are often used as immunogens for vaccines to generate neutralizing antibodies and frequently targeted for inhibition by small molecules that might block host receptor binding and/or membrane fusion (Li, 2016; Watanabe et al., 2019)."}