PMC:7443692 / 31986-32563 JSONTXT

{"project":"LitCovid-sample-PD-NCBITaxon","denotations":[{"id":"T85","span":{"begin":47,"end":52},"obj":"Species"},{"id":"T86","span":{"begin":228,"end":233},"obj":"Species"},{"id":"T87","span":{"begin":252,"end":257},"obj":"Species"},{"id":"T88","span":{"begin":477,"end":482},"obj":"Species"}],"attributes":[{"id":"A85","pred":"ncbi_taxonomy_id","subj":"T85","obj":"NCBItxid:9606"},{"id":"A86","pred":"ncbi_taxonomy_id","subj":"T86","obj":"NCBItxid:9606"},{"id":"A87","pred":"ncbi_taxonomy_id","subj":"T87","obj":"NCBItxid:9606"},{"id":"A88","pred":"ncbi_taxonomy_id","subj":"T88","obj":"NCBItxid:9606"}],"namespaces":[{"prefix":"NCBItxid","uri":"http://purl.bioontology.org/ontology/NCBITAXON/"}],"text":"3D Structural Modeling of Glycosylated Soluble Human ACE2\nResults from glycomics and glycoproteomics experiments were combined with results from bioinformatics analyses and used to model several versions of glycosylated soluble human ACE2.\n(A) Soluble human ACE2 model from MD simulations displaying abundance glycoforms, interaction surface with S, and sequence variants. N546 variant is boxed that would remove N-linked glycosylation at that site (see Video S2).\n(B) Soluble human ACE2 model from MD simulations displaying processed glycoforms and interaction surface with S."}

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T192","span":{"begin":58,"end":239},"obj":"Sentence"},{"id":"T193","span":{"begin":240,"end":372},"obj":"Sentence"},{"id":"T194","span":{"begin":373,"end":464},"obj":"Sentence"},{"id":"T195","span":{"begin":465,"end":577},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"3D Structural Modeling of Glycosylated Soluble Human ACE2\nResults from glycomics and glycoproteomics experiments were combined with results from bioinformatics analyses and used to model several versions of glycosylated soluble human ACE2.\n(A) Soluble human ACE2 model from MD simulations displaying abundance glycoforms, interaction surface with S, and sequence variants. N546 variant is boxed that would remove N-linked glycosylation at that site (see Video S2).\n(B) Soluble human ACE2 model from MD simulations displaying processed glycoforms and interaction surface with S."}

{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T2164","span":{"begin":53,"end":57},"obj":"Protein"},{"id":"T2165","span":{"begin":234,"end":238},"obj":"Protein"},{"id":"T2166","span":{"begin":258,"end":262},"obj":"Protein"},{"id":"T2167","span":{"begin":483,"end":487},"obj":"Protein"}],"attributes":[{"id":"A2164","pred":"uniprot_id","subj":"T2164","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A2165","pred":"uniprot_id","subj":"T2165","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A2166","pred":"uniprot_id","subj":"T2166","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A2167","pred":"uniprot_id","subj":"T2167","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"}],"text":"3D Structural Modeling of Glycosylated Soluble Human ACE2\nResults from glycomics and glycoproteomics experiments were combined with results from bioinformatics analyses and used to model several versions of glycosylated soluble human ACE2.\n(A) Soluble human ACE2 model from MD simulations displaying abundance glycoforms, interaction surface with S, and sequence variants. N546 variant is boxed that would remove N-linked glycosylation at that site (see Video S2).\n(B) Soluble human ACE2 model from MD simulations displaying processed glycoforms and interaction surface with S."}

{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T93","span":{"begin":444,"end":448},"obj":"http://purl.obolibrary.org/obo/BFO_0000029"}],"text":"3D Structural Modeling of Glycosylated Soluble Human ACE2\nResults from glycomics and glycoproteomics experiments were combined with results from bioinformatics analyses and used to model several versions of glycosylated soluble human ACE2.\n(A) Soluble human ACE2 model from MD simulations displaying abundance glycoforms, interaction surface with S, and sequence variants. N546 variant is boxed that would remove N-linked glycosylation at that site (see Video S2).\n(B) Soluble human ACE2 model from MD simulations displaying processed glycoforms and interaction surface with S."}

{"project":"LitCovid-sample-PD-GO-BP-0","denotations":[{"id":"T75","span":{"begin":422,"end":435},"obj":"http://purl.obolibrary.org/obo/GO_0070085"}],"text":"3D Structural Modeling of Glycosylated Soluble Human ACE2\nResults from glycomics and glycoproteomics experiments were combined with results from bioinformatics analyses and used to model several versions of glycosylated soluble human ACE2.\n(A) Soluble human ACE2 model from MD simulations displaying abundance glycoforms, interaction surface with S, and sequence variants. N546 variant is boxed that would remove N-linked glycosylation at that site (see Video S2).\n(B) Soluble human ACE2 model from MD simulations displaying processed glycoforms and interaction surface with S."}

{"project":"LitCovid-sample-GO-BP","denotations":[{"id":"T71","span":{"begin":422,"end":435},"obj":"http://purl.obolibrary.org/obo/GO_0070085"}],"text":"3D Structural Modeling of Glycosylated Soluble Human ACE2\nResults from glycomics and glycoproteomics experiments were combined with results from bioinformatics analyses and used to model several versions of glycosylated soluble human ACE2.\n(A) Soluble human ACE2 model from MD simulations displaying abundance glycoforms, interaction surface with S, and sequence variants. N546 variant is boxed that would remove N-linked glycosylation at that site (see Video S2).\n(B) Soluble human ACE2 model from MD simulations displaying processed glycoforms and interaction surface with S."}