PMC:7441788 / 8199-8397 JSONTXT

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T87","span":{"begin":52,"end":60},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":" of ACE2 [13]. Therefore, the mechanism of anti-CoV activity of CQ/HCQ may be at least partly related to the impairment of terminal glycosylation of ACE2, which may result in reduced binding affinit"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T92","span":{"begin":64,"end":66},"obj":"Chemical"}],"attributes":[{"id":"A92","pred":"chebi_id","subj":"T92","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"}],"text":" of ACE2 [13]. Therefore, the mechanism of anti-CoV activity of CQ/HCQ may be at least partly related to the impairment of terminal glycosylation of ACE2, which may result in reduced binding affinit"}

{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T65","span":{"begin":64,"end":66},"obj":"Chemical"}],"attributes":[{"id":"A65","pred":"chebi_id","subj":"T65","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"}],"text":" of ACE2 [13]. Therefore, the mechanism of anti-CoV activity of CQ/HCQ may be at least partly related to the impairment of terminal glycosylation of ACE2, which may result in reduced binding affinit"}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"354","span":{"begin":4,"end":8},"obj":"Gene"},{"id":"355","span":{"begin":149,"end":153},"obj":"Gene"},{"id":"363","span":{"begin":48,"end":51},"obj":"Species"},{"id":"367","span":{"begin":64,"end":66},"obj":"Chemical"},{"id":"368","span":{"begin":67,"end":70},"obj":"Chemical"}],"attributes":[{"id":"A354","pred":"pubann:denotes","subj":"354","obj":"Gene:59272"},{"id":"A355","pred":"pubann:denotes","subj":"355","obj":"Gene:59272"},{"id":"A363","pred":"pubann:denotes","subj":"363","obj":"Tax:11118"},{"id":"A367","pred":"pubann:denotes","subj":"367","obj":"MESH:D002738"},{"id":"A368","pred":"pubann:denotes","subj":"368","obj":"MESH:D006886"}],"text":" of ACE2 [13]. Therefore, the mechanism of anti-CoV activity of CQ/HCQ may be at least partly related to the impairment of terminal glycosylation of ACE2, which may result in reduced binding affinit"}

{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T85","span":{"begin":4,"end":8},"obj":"Protein"},{"id":"T86","span":{"begin":149,"end":153},"obj":"Protein"}],"attributes":[{"id":"A85","pred":"uniprot_id","subj":"T85","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"},{"id":"A86","pred":"uniprot_id","subj":"T86","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"}],"text":" of ACE2 [13]. Therefore, the mechanism of anti-CoV activity of CQ/HCQ may be at least partly related to the impairment of terminal glycosylation of ACE2, which may result in reduced binding affinit"}

{"project":"LitCovid-sample-PD-GO-BP-0","denotations":[{"id":"T8","span":{"begin":123,"end":145},"obj":"http://purl.obolibrary.org/obo/GO_0033578"},{"id":"T9","span":{"begin":132,"end":145},"obj":"http://purl.obolibrary.org/obo/GO_0070085"}],"text":" of ACE2 [13]. Therefore, the mechanism of anti-CoV activity of CQ/HCQ may be at least partly related to the impairment of terminal glycosylation of ACE2, which may result in reduced binding affinit"}

{"project":"LitCovid-sample-GO-BP","denotations":[{"id":"T8","span":{"begin":123,"end":145},"obj":"http://purl.obolibrary.org/obo/GO_0033578"},{"id":"T9","span":{"begin":132,"end":145},"obj":"http://purl.obolibrary.org/obo/GO_0070085"}],"text":" of ACE2 [13]. Therefore, the mechanism of anti-CoV activity of CQ/HCQ may be at least partly related to the impairment of terminal glycosylation of ACE2, which may result in reduced binding affinit"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T8","span":{"begin":123,"end":145},"obj":"http://purl.obolibrary.org/obo/GO_0033578"},{"id":"T9","span":{"begin":132,"end":145},"obj":"http://purl.obolibrary.org/obo/GO_0070085"}],"text":" of ACE2 [13]. Therefore, the mechanism of anti-CoV activity of CQ/HCQ may be at least partly related to the impairment of terminal glycosylation of ACE2, which may result in reduced binding affinit"}

{"project":"LitCovid-PubTator","denotations":[{"id":"354","span":{"begin":4,"end":8},"obj":"Gene"},{"id":"355","span":{"begin":149,"end":153},"obj":"Gene"},{"id":"363","span":{"begin":48,"end":51},"obj":"Species"},{"id":"367","span":{"begin":64,"end":66},"obj":"Chemical"},{"id":"368","span":{"begin":67,"end":70},"obj":"Chemical"}],"attributes":[{"id":"A354","pred":"tao:has_database_id","subj":"354","obj":"Gene:59272"},{"id":"A355","pred":"tao:has_database_id","subj":"355","obj":"Gene:59272"},{"id":"A363","pred":"tao:has_database_id","subj":"363","obj":"Tax:11118"},{"id":"A367","pred":"tao:has_database_id","subj":"367","obj":"MESH:D002738"},{"id":"A368","pred":"tao:has_database_id","subj":"368","obj":"MESH:D006886"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":" of ACE2 [13]. Therefore, the mechanism of anti-CoV activity of CQ/HCQ may be at least partly related to the impairment of terminal glycosylation of ACE2, which may result in reduced binding affinit"}

{"project":"2_test","denotations":[{"id":"32496926-16115318-132195668","span":{"begin":10,"end":12},"obj":"16115318"}],"text":" of ACE2 [13]. Therefore, the mechanism of anti-CoV activity of CQ/HCQ may be at least partly related to the impairment of terminal glycosylation of ACE2, which may result in reduced binding affinit"}