> top > docs > PMC:7441788 > spans > 7426-14473 > annotations

PMC:7441788 / 7426-14473 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T26 129-136 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T27 248-260 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T28 248-252 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T29 379-392 Body_part denotes cell membrane http://purl.org/sig/ont/fma/fma63841
T30 379-383 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T31 455-460 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T32 586-593 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T33 671-683 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T34 671-675 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T35 1003-1010 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T36 1398-1405 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T37 1444-1455 Body_part denotes ganglioside http://purl.org/sig/ont/fma/fma82816
T38 1623-1626 Body_part denotes MHC http://purl.org/sig/ont/fma/fma84079
T39 1700-1704 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T40 1755-1764 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T41 1804-1809 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T42 1816-1821 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T43 1985-1992 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T44 2001-2004 Body_part denotes MHC http://purl.org/sig/ont/fma/fma84079
T45 2009-2041 Body_part denotes major histocompatibility complex http://purl.org/sig/ont/fma/fma84079
T46 2125-2127 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T47 2129-2140 Body_part denotes interleukin http://purl.org/sig/ont/fma/fma86578
T48 2189-2196 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T49 2197-2215 Body_part denotes membrane receptors http://purl.org/sig/ont/fma/fma0326969
T50 2235-2240 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T51 2288-2301 Body_part denotes glycoproteins http://purl.org/sig/ont/fma/fma62925
T52 2306-2318 Body_part denotes gangliosides http://purl.org/sig/ont/fma/fma82816
T53 2592-2604 Body_part denotes gangliosides http://purl.org/sig/ont/fma/fma82816
T54 2617-2629 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T55 2617-2621 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T56 2689-2701 Body_part denotes gangliosides http://purl.org/sig/ont/fma/fma82816
T57 2770-2777 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T58 2781-2793 Body_part denotes gangliosides http://purl.org/sig/ont/fma/fma82816
T59 3036-3047 Body_part denotes ganglioside http://purl.org/sig/ont/fma/fma82816
T60 3132-3135 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T61 3155-3159 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T62 3276-3285 Body_part denotes endosomal http://purl.org/sig/ont/fma/fma67180
T63 3286-3297 Body_part denotes compartment http://purl.org/sig/ont/fma/fma76577
T64 3529-3535 Body_part denotes serine http://purl.org/sig/ont/fma/fma82764
T65 3587-3594 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T66 3770-3778 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T67 3935-3940 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T68 4030-4037 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T69 4179-4194 Body_part denotes early endosomes http://purl.org/sig/ont/fma/fma67463
T70 4234-4239 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T71 4367-4376 Body_part denotes endosomal http://purl.org/sig/ont/fma/fma67180
T72 4501-4509 Body_part denotes endosome http://purl.org/sig/ont/fma/fma67180
T73 4556-4565 Body_part denotes lysosomal http://purl.org/sig/ont/fma/fma63836
T74 4678-4682 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T75 4750-4757 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T76 4807-4819 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T77 4807-4811 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T78 4963-4967 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T79 4968-4984 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T80 4979-4984 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T81 5560-5564 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T82 5580-5588 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T83 5751-5760 Body_part denotes lysosomal http://purl.org/sig/ont/fma/fma63836
T84 5802-5834 Body_part denotes major histocompatibility complex http://purl.org/sig/ont/fma/fma84079
T85 5836-5839 Body_part denotes MHC http://purl.org/sig/ont/fma/fma84079
T86 5916-5920 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T87 5988-5993 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T88 6016-6025 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T89 6034-6045 Body_part denotes interleukin http://purl.org/sig/ont/fma/fma86578
T90 6046-6052 Body_part denotes (IL)-1 http://purl.org/sig/ont/fma/fma86583
T91 6047-6049 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T92 6054-6056 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T93 6109-6114 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T94 6121-6126 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T95 6162-6171 Body_part denotes endosomal http://purl.org/sig/ont/fma/fma67180
T96 6308-6317 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T97 6409-6418 Body_part denotes cytosolic http://purl.org/sig/ont/fma/fma66836
T98 6419-6422 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T99 6524-6526 Body_part denotes A2 http://purl.org/sig/ont/fma/fma66595
T100 6686-6695 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T101 6733-6735 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T102 6742-6744 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T103 6768-6774 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T104 6852-6860 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T5 4963-4967 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T63 37-45 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T64 140-148 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T65 488-496 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T66 612-620 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T67 992-996 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T68 1266-1274 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T69 1862-1870 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T70 1872-1896 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T71 2149-2154 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T72 2217-2226 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T73 2385-2394 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T74 2420-2428 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T75 2510-2518 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T76 3793-3801 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T77 3849-3858 Disease denotes hepatitis http://purl.obolibrary.org/obo/MONDO_0002251
T78 3907-3915 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T79 4017-4025 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T80 4122-4130 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T81 4163-4171 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T82 4302-4310 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T83 4851-4860 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T84 4890-4898 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T85 5341-5347 Disease denotes dengue http://purl.obolibrary.org/obo/MONDO_0005502
T86 6063-6068 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T87 6816-6824 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T88 6879-6882 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T90 6994-6997 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T92 7027-7035 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T73 63-71 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T74 199-201 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T75 206-208 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T76 206-208 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T77 219-221 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T78 248-252 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T79 313-318 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T80 339-341 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T81 339-341 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T82 360-365 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T83 379-383 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T84 384-392 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T85 448-460 http://purl.obolibrary.org/obo/CLO_0051719 denotes VeroE6 cells
T86 671-675 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T87 825-833 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T88 1472-1480 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T89 1559-1569 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T90 1692-1695 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T91 1698-1704 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T92 1714-1723 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T93 1788-1798 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T94 1802-1809 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T95 1814-1821 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T96 1975-1984 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T97 2197-2205 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T98 2235-2240 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T99 2338-2339 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T100 2355-2362 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T101 2460-2461 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T102 2543-2544 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T103 2617-2621 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T104 2941-2949 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T105 3089-3097 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T106 3136-3143 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T107 3155-3159 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T108 3184-3185 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T109 3241-3249 http://purl.obolibrary.org/obo/UBERON_0000158 denotes Membrane
T110 3389-3399 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T111 3595-3605 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T112 3624-3632 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T113 3737-3747 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T114 3751-3752 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T115 3843-3848 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T116 3859-3864 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T117 3881-3882 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T118 3925-3928 http://purl.obolibrary.org/obo/CLO_0001230 denotes 293
T119 3925-3928 http://purl.obolibrary.org/obo/CLO_0037237 denotes 293
T120 3925-3928 http://purl.obolibrary.org/obo/CLO_0050903 denotes 293
T121 3925-3928 http://purl.obolibrary.org/obo/CLO_0054249 denotes 293
T122 3925-3928 http://purl.obolibrary.org/obo/CLO_0054250 denotes 293
T123 3925-3928 http://purl.obolibrary.org/obo/CLO_0054251 denotes 293
T124 3925-3928 http://purl.obolibrary.org/obo/CLO_0054252 denotes 293
T125 3935-3940 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T126 4044-4045 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T127 4227-4239 http://purl.obolibrary.org/obo/CLO_0051719 denotes VeroE6 cells
T128 4448-4456 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T129 4556-4565 http://purl.obolibrary.org/obo/GO_0005764 denotes lysosomal
T130 4613-4618 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T131 4628-4637 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membranes
T132 4678-4682 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T133 4683-4692 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T134 4740-4749 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T135 4790-4797 http://purl.obolibrary.org/obo/SO_0000418 denotes signals
T136 4807-4811 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T137 4882-4884 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T138 4947-4952 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T139 4963-4984 http://purl.obolibrary.org/obo/CL_0000082 denotes lung epithelial cells
T140 4986-4990 http://purl.obolibrary.org/obo/CLO_0007158 denotes L132
T141 5016-5026 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T142 5175-5185 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T143 5297-5306 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T144 5348-5353 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T145 5354-5362 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T146 5418-5426 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T147 5446-5456 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T148 5558-5564 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T149 5565-5575 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T150 5751-5760 http://purl.obolibrary.org/obo/GO_0005764 denotes lysosomal
T151 5761-5769 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T152 5872-5882 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T153 5914-5920 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T154 5921-5931 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T155 5980-5983 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T156 5986-5993 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T157 5995-5997 http://purl.obolibrary.org/obo/CLO_0053794 denotes 41
T158 6107-6114 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T159 6119-6126 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T160 6219-6228 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T161 6279-6289 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T162 6386-6394 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T163 6441-6458 http://purl.obolibrary.org/obo/PR_000024990 denotes type I interferon
T164 6524-6526 http://purl.obolibrary.org/obo/CLO_0001562 denotes A2
T165 6620-6622 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T166 6768-6774 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T83 18-20 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T84 129-136 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T85 206-208 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T86 270-281 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T87 339-341 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T88 434-436 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T89 517-519 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T90 586-593 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T91 704-706 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T92 837-839 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T93 1003-1010 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T94 1127-1129 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T95 1191-1193 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T96 1224-1233 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T97 1398-1405 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T98 1428-1439 Chemical denotes sialic acid http://purl.obolibrary.org/obo/CHEBI_26667
T99 1435-1439 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T100 1444-1455 Chemical denotes ganglioside http://purl.obolibrary.org/obo/CHEBI_28892
T101 1633-1635 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T102 1829-1840 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T103 1898-1900 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T104 1902-1913 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T105 1920-1938 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T106 1967-1974 Chemical denotes mitogen http://purl.obolibrary.org/obo/CHEBI_52290
T107 1985-1992 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T108 2005-2007 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T109 2048-2050 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T110 2083-2097 Chemical denotes cyclic GMP-AMP http://purl.obolibrary.org/obo/CHEBI_71580
T111 2090-2093 Chemical denotes GMP http://purl.obolibrary.org/obo/CHEBI_17345|http://purl.obolibrary.org/obo/CHEBI_58115
T113 2094-2097 Chemical denotes AMP http://purl.obolibrary.org/obo/CHEBI_16027|http://purl.obolibrary.org/obo/CHEBI_28971|http://purl.obolibrary.org/obo/CHEBI_456215
T116 2113-2123 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T117 2125-2127 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T119 2189-2196 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T120 2265-2276 Chemical denotes sialic acid http://purl.obolibrary.org/obo/CHEBI_26667
T121 2272-2276 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T122 2288-2301 Chemical denotes glycoproteins http://purl.obolibrary.org/obo/CHEBI_17089
T123 2306-2318 Chemical denotes gangliosides http://purl.obolibrary.org/obo/CHEBI_28892
T124 2592-2604 Chemical denotes gangliosides http://purl.obolibrary.org/obo/CHEBI_28892
T125 2638-2649 Chemical denotes sialic acid http://purl.obolibrary.org/obo/CHEBI_26667
T126 2645-2649 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T127 2659-2661 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T128 2672-2684 Chemical denotes sialic acids http://purl.obolibrary.org/obo/CHEBI_26667
T129 2679-2684 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T130 2689-2701 Chemical denotes gangliosides http://purl.obolibrary.org/obo/CHEBI_28892
T131 2770-2777 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T132 2781-2793 Chemical denotes gangliosides http://purl.obolibrary.org/obo/CHEBI_28892
T133 2800-2802 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T134 2828-2835 Chemical denotes quinone http://purl.obolibrary.org/obo/CHEBI_36141
T135 2886-2898 Chemical denotes sialic acids http://purl.obolibrary.org/obo/CHEBI_26667
T136 2893-2898 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T137 2953-2955 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T138 3020-3031 Chemical denotes sialic acid http://purl.obolibrary.org/obo/CHEBI_26667
T139 3027-3031 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T140 3036-3047 Chemical denotes ganglioside http://purl.obolibrary.org/obo/CHEBI_28892
T141 3482-3484 Chemical denotes PC http://purl.obolibrary.org/obo/CHEBI_16110|http://purl.obolibrary.org/obo/CHEBI_49183|http://purl.obolibrary.org/obo/CHEBI_53201|http://purl.obolibrary.org/obo/CHEBI_55395|http://purl.obolibrary.org/obo/CHEBI_57643|http://purl.obolibrary.org/obo/CHEBI_61433
T147 3529-3535 Chemical denotes serine http://purl.obolibrary.org/obo/CHEBI_17822
T148 3587-3594 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T149 3770-3778 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T150 4030-4037 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T151 4101-4103 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T152 4269-4271 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T153 4346-4348 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T154 4460-4462 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T155 4732-4739 Chemical denotes mitogen http://purl.obolibrary.org/obo/CHEBI_52290
T156 4750-4757 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T157 4827-4834 Chemical denotes nucleus http://purl.obolibrary.org/obo/CHEBI_33252
T158 4905-4907 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T159 5108-5131 Chemical denotes reactive oxygen species http://purl.obolibrary.org/obo/CHEBI_26523
T160 5117-5123 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T161 5133-5136 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T162 5287-5296 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T163 5380-5382 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T164 5408-5417 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T165 5600-5602 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T166 5685-5701 Chemical denotes immunomodulators http://purl.obolibrary.org/obo/CHEBI_50846
T167 5735-5737 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T168 5782-5789 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T169 5847-5849 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T170 6000-6002 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T171 6047-6049 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T173 6054-6056 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T175 6324-6326 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T176 6347-6361 Chemical denotes cyclic GMP-AMP http://purl.obolibrary.org/obo/CHEBI_71580
T177 6354-6357 Chemical denotes GMP http://purl.obolibrary.org/obo/CHEBI_17345|http://purl.obolibrary.org/obo/CHEBI_58115
T179 6358-6361 Chemical denotes AMP http://purl.obolibrary.org/obo/CHEBI_16027|http://purl.obolibrary.org/obo/CHEBI_28971|http://purl.obolibrary.org/obo/CHEBI_456215
T182 6419-6422 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T183 6448-6458 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T184 6486-6488 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T185 6555-6571 Chemical denotes arachidonic acid http://purl.obolibrary.org/obo/CHEBI_15843
T186 6567-6571 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T187 6604-6618 Chemical denotes prostaglandins http://purl.obolibrary.org/obo/CHEBI_26333
T188 6733-6735 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T190 6742-6744 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T192 6959-6961 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638

LitCovid-sample-MedDRA

Id Subject Object Predicate Lexical cue meddra_id
T4 270-299 http://purl.bioontology.org/ontology/MEDDRA/10022891 denotes angiotensin-converting enzyme http://purl.bioontology.org/ontology/MEDDRA/10050289
T5 403-416 http://purl.bioontology.org/ontology/MEDDRA/10022891 denotes investigation http://purl.bioontology.org/ontology/MEDDRA/10062026
T6 1829-1858 http://purl.bioontology.org/ontology/MEDDRA/10022891 denotes angiotensin-converting enzyme http://purl.bioontology.org/ontology/MEDDRA/10050289
T7 4052-4064 http://purl.bioontology.org/ontology/MEDDRA/10022891 denotes investigated http://purl.bioontology.org/ontology/MEDDRA/10062026

LitCovid-sample-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T58 18-20 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T59 129-136 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T60 270-281 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T61 434-436 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T62 517-519 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T63 586-593 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T64 704-706 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T65 837-839 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T66 1003-1010 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T67 1127-1129 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T68 1191-1193 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T69 1398-1405 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T70 1428-1439 Chemical denotes sialic acid http://purl.obolibrary.org/obo/CHEBI_26667
T71 1444-1455 Chemical denotes ganglioside http://purl.obolibrary.org/obo/CHEBI_28892
T72 1829-1840 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T73 1898-1900 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T74 1902-1913 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T75 1920-1938 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T76 1985-1992 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T77 2083-2097 Chemical denotes cyclic GMP-AMP http://purl.obolibrary.org/obo/CHEBI_71580
T78 2189-2196 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T79 2265-2276 Chemical denotes sialic acid http://purl.obolibrary.org/obo/CHEBI_26667
T80 2288-2301 Chemical denotes glycoproteins http://purl.obolibrary.org/obo/CHEBI_17089
T81 2306-2318 Chemical denotes gangliosides http://purl.obolibrary.org/obo/CHEBI_28892
T82 2592-2604 Chemical denotes gangliosides http://purl.obolibrary.org/obo/CHEBI_28892
T83 2638-2649 Chemical denotes sialic acid http://purl.obolibrary.org/obo/CHEBI_26667
T84 2659-2661 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T85 2672-2684 Chemical denotes sialic acids http://purl.obolibrary.org/obo/CHEBI_26667
T86 2689-2701 Chemical denotes gangliosides http://purl.obolibrary.org/obo/CHEBI_28892
T87 2770-2777 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T88 2781-2793 Chemical denotes gangliosides http://purl.obolibrary.org/obo/CHEBI_28892
T89 2800-2802 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T90 2828-2835 Chemical denotes quinone http://purl.obolibrary.org/obo/CHEBI_36141
T91 2886-2898 Chemical denotes sialic acids http://purl.obolibrary.org/obo/CHEBI_26667
T92 2953-2955 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T93 3020-3031 Chemical denotes sialic acid http://purl.obolibrary.org/obo/CHEBI_26667
T94 3036-3047 Chemical denotes ganglioside http://purl.obolibrary.org/obo/CHEBI_28892
T95 3132-3135 Chemical denotes RNA http://purl.obolibrary.org/obo/CHEBI_33697
T96 3529-3535 Chemical denotes serine http://purl.obolibrary.org/obo/CHEBI_17822
T97 3587-3594 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T98 3770-3778 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T99 4030-4037 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T100 4101-4103 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T101 4269-4271 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T102 4346-4348 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T103 4460-4462 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T104 4750-4757 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T105 4905-4907 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T106 5108-5131 Chemical denotes reactive oxygen species http://purl.obolibrary.org/obo/CHEBI_26523
T107 5133-5136 Chemical denotes ROS http://purl.obolibrary.org/obo/CHEBI_26523
T108 5380-5382 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T109 5600-5602 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T110 5735-5737 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T111 6000-6002 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T112 6324-6326 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T113 6347-6361 Chemical denotes cyclic GMP-AMP http://purl.obolibrary.org/obo/CHEBI_71580
T114 6419-6422 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T115 6486-6488 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638
T116 6555-6571 Chemical denotes arachidonic acid http://purl.obolibrary.org/obo/CHEBI_15843
T117 6604-6618 Chemical denotes prostaglandins http://purl.obolibrary.org/obo/CHEBI_26333
T118 6959-6961 Chemical denotes CQ http://purl.obolibrary.org/obo/CHEBI_3638

LitCovid-sample-PD-NCBITaxon

Id Subject Object Predicate Lexical cue ncbi_taxonomy_id
T67 37-45 Species denotes COVID-19 NCBItxid:2697049
T68 140-150 Species denotes SARS-CoV-2 NCBItxid:2697049
T69 488-498 Species denotes SARS-CoV-2 NCBItxid:2697049
T70 612-620 Species denotes SARS-CoV NCBItxid:694009
T71 992-996 Species denotes SARS NCBItxid:694009
T72 1266-1274 Species denotes COVID-19 NCBItxid:2697049
T73 1862-1870 Species denotes COVID-19 NCBItxid:2697049
T74 1872-1896 Species denotes coronavirus disease 2019 NCBItxid:2697049
T75 2355-2362 Species denotes viruses NCBItxid:10239
T76 2420-2428 Species denotes SARS-CoV NCBItxid:694009
T77 2438-2447 Species denotes HCoV-OC43 NCBItxid:31631
T78 2510-2520 Species denotes SARS-CoV-2 NCBItxid:2697049
T79 3132-3143 Species denotes RNA viruses NCBItxid:2559587
T80 3793-3801 Species denotes SARS-CoV NCBItxid:694009
T81 3808-3816 Species denotes MERS-CoV NCBItxid:1335626
T82 3823-3832 Species denotes HCoV-229E NCBItxid:11137
T83 3843-3866 Species denotes mouse hepatitis virus 2 NCBItxid:76344
T84 3868-3871 Species denotes MHV NCBItxid:11138
T85 3907-3917 Species denotes SARS-CoV-2 NCBItxid:2697049
T86 4017-4027 Species denotes SARS-CoV-2 NCBItxid:2697049
T87 4122-4132 Species denotes SARS-CoV-2 NCBItxid:2697049
T88 4163-4173 Species denotes SARS-CoV-2 NCBItxid:2697049
T89 4302-4312 Species denotes SARS-CoV-2 NCBItxid:2697049
T90 4877-4880 Species denotes MHV NCBItxid:11138
T91 4890-4898 Species denotes SARS-CoV NCBItxid:694009
T92 4922-4931 Species denotes HCoV-229E NCBItxid:11137
T93 4947-4952 Species denotes human NCBItxid:9606
T94 5341-5353 Species denotes dengue virus NCBItxid:12637
T95 6816-6826 Species denotes SARS-CoV-2 NCBItxid:2697049
T96 7027-7035 Species denotes COVID-19 NCBItxid:2697049

LitCovid-sample-sentences

Id Subject Object Predicate Lexical cue
T58 0-2 Sentence denotes 4.
T59 4-45 Sentence denotes Mechanisms of CQ/HCQ in treating COVID-19
T60 47-51 Sentence denotes 4.1.
T61 53-71 Sentence denotes Antiviral activity
T62 73-79 Sentence denotes 4.1.1.
T63 81-122 Sentence denotes Hindrance of receptor recognition process
T64 123-214 Sentence denotes The S protein of SARS-CoV-2 is cleaved by host proteases into two subunits, S1 and S2 [19].
T65 215-398 Sentence denotes The S1 subunit binds to the host cell surface receptor angiotensin-converting enzyme 2 (ACE2) for virus attachment, and the S2 subunit fuses the virus and the host cell membrane [19].
T66 399-787 Sentence denotes The investigation of the effect of CQ on ACE2 in VeroE6 cells showed that effective anti-SARS-CoV-2 concentrations of CQ had no significant effect on the synthesis and glycosylation of S protein on the surface of SARS-CoV, and although it had no significant effect on the cell surface expression of ACE2, CQ could destroy the glycosylation at the terminal glycosylation site of ACE2 [13].
T67 788-1061 Sentence denotes Therefore, the mechanism of anti-CoV activity of CQ/HCQ may be at least partly related to the impairment of terminal glycosylation of ACE2, which may result in reduced binding affinities between ACE2 and SARS CoV S protein, thereby blocking receptor recognition (Figure 1).
T68 1062-1071 Sentence denotes Figure 1.
T69 1072-1190 Sentence denotes Schematic representation of the possible mechanisms of CQ/HCQ against CoVs replication and modulating immune response.
T70 1191-1822 Sentence denotes CQ/HCQ may synergistically exert antiviral and immunomodulatory effects on COVID-19 through multiple mechanisms including hindering the receptor recognition process by influencing the affinity of ACE2 and S protein, and the affinity for sialic acid and ganglioside; inhibiting the membrane fusion process by suppressing endolysosome acidification; suppressing the p38 activation and affecting host defense machinery, and preventing MHC class II expression (block expression of CD154 on the surface of CD4 + T cell) and TLR signaling and reducing the production of cytokines through inhibiting the activation of T cells and B cells.
T71 1823-2173 Sentence denotes ACE2, angiotensin-converting enzyme 2; COVID-19, coronavirus disease 2019; CQ, chloroquine; HCQ, hydroxychloroquine; CoVs, coronaviruses; MAPK, mitogen-activated protein kinase; MHC-II, major histocompatibility complex class II; TLR, toll-like receptor; cGAS, cyclic GMP-AMP synthase; IFN, interferon; IL, interleukin; TNF-α, tumor necrosis factor-α.
T72 2174-2459 Sentence denotes In addition to protein membrane receptors, infection of host cells by HCoVs also relies on sialic acid-containing glycoproteins and gangliosides, which are used by a broad range of viruses as receptors, such as influenza [20] and HCoVs including SARS-CoV [21] and HCoV-OC43 [13,22,23].
T73 2460-2658 Sentence denotes A recent molecular structure analysis showed that SARS-CoV-2 not only uses ACE2 as a receptor, but also recognizes highly conserved gangliosides on the host cell surface through sialic acid [24,25].
T74 2659-2799 Sentence denotes CQ/HCQ binds sialic acids and gangliosides with high affinity, which can prevent the attachment of SARSCoV-2 S protein to gangliosides [25].
T75 2800-2907 Sentence denotes CQ had inhibitory effect on quinone reductase 2 (QR2) involved in the biosynthesis of sialic acids [26,27].
T76 2908-3059 Sentence denotes Hence, the mechanism of anti-CoV activity of CQ/HCQ may also be related to hindering the recognition process of sialic acid and ganglioside (Figure 1).
T77 3061-3067 Sentence denotes 4.1.2.
T78 3069-3112 Sentence denotes Interference of the membrane fusion process
T79 3113-3240 Sentence denotes CoVs are enveloped RNA viruses, and their cell entry processes involve a principal route of receptor-mediated endocytosis [28].
T80 3241-3405 Sentence denotes Membrane fusion takes place in the endosomal compartment after endocytosis, which needs additional triggers such as pH acidification or proteolytic activation [29].
T81 3406-3645 Sentence denotes Multiple cellular proteases, such as trypsin, furin, proprotein convertase (PC) family, cathepsins, transmembrane protease/serine (TMPRSS) proteases and elastase, are involved in S protein activation, which can induce membrane fusion [30].
T82 3646-3880 Sentence denotes Among them, cathepsin L, with anoptimal pH of 3.0 to 6.5, is most commonly associated with activation of a variety of CoV S proteins [30], such as SARS-CoV [19], MERS-CoV [31], HCoV-229E [32], and mouse hepatitis virus 2 (MHV-2) [33].
T83 3881-4043 Sentence denotes A recent study found that SARS-CoV-2 enters 293/hACE2 cells mainly through endocytosis, in which cathepsin L is critical for priming of SARS-CoV-2 S protein [24].
T84 4044-4393 Sentence denotes A study investigated the detailed mechanism of action of CQ/HCQ in inhibiting SARS-CoV-2 entry, and co-localization of SARS-CoV-2 with early endosomes (EEs) or endolysosomes (ELs) in VeroE6 cells, and the results showed that CQ/HCQ hampered the transport of SARS-CoV-2 from EEs to ELs, indicating that CQ/HCQ might inhibit endosomal maturation [17].
T85 4394-4657 Sentence denotes These studies revealed that the mechanism of anti-CoV activity of CQ/HCQ may involve the inhibition of the endosome acidification process, which might inactivate lysosomal proteases, thus interfering with the fusion of virus and host membranes [34,35] (Figure 1).
T86 4659-4665 Sentence denotes 4.1.3.
T87 4667-4727 Sentence denotes Effects on cell signaling pathway and host defense machinery
T88 4728-4904 Sentence denotes The mitogen-activated protein kinase (MAPK) pathway transmits signals from the cell surface to the nucleus involved in the infection of CoVs such as MHV [36] and SARS-CoV [37].
T89 4905-5044 Sentence denotes CQ could inhibit HCoV-229E replication in human embryonic lung epithelial cells (L132) through suppressing the activation of p38 MAPK [38].
T90 5045-5210 Sentence denotes Moreover, HCQ could markedly induce the production of cellular reactive oxygen species (ROS), which play an important role in the activation of innate immunity [39].
T91 5211-5368 Sentence denotes HCQ also could trigger the host defense mechanism through the mitochondrial antiviral signaling (MAVS) pathway, resulting in anti-dengue virus activity [39].
T92 5369-5529 Sentence denotes Therefore, CQ/HCQ may also exert their antiviral activity by suppressing the activation of p38 MAPK pathway and affecting the host defense machinery (Figure 1).
T93 5531-5535 Sentence denotes 4.2.
T94 5537-5599 Sentence denotes Inhibitory effect on T cell activation and cytokine production
T95 5600-5702 Sentence denotes CQ/HCQ regulate the release of various pro-inflammatory factors, which are important immunomodulators.
T96 5703-5888 Sentence denotes Intracellular alkalinization by CQ/HCQ inhibits lysosomal activity, preventing antigen processing, major histocompatibility complex (MHC) class II expression and immune activation [40].
T97 5889-5999 Sentence denotes This process can inhibit T cell activation and block expression of CD154 on the surface of CD4 + T cells [41].
T98 6000-6132 Sentence denotes CQ also reduces cytokines such as interleukin (IL)-1, IL-6 and tumor necrosis factor-α (TNF-α) produced by T cells and B cells [42].
T99 6133-6323 Sentence denotes At the same time, changes of endosomal pH can interfere with Toll-like receptor (TLR) signaling, such as TLR7 and TLR9 processing, inhibiting the activation and production of cytokines [43].
T100 6324-6475 Sentence denotes CQ/HCQ also weaken the cyclic GMP-AMP (cGAMP) synthase (cGAS) activity by inhibiting cytosolic DNA, thereby reducing type I interferon production [44].
T101 6476-6624 Sentence denotes In vitro, CQ/HCQ can also inhibit phospholipase A2, altering the metabolism of arachidonic acid, and reducing the production of prostaglandins [45].
T102 6625-6920 Sentence denotes Some clinical studies have found that high concentrations of cytokines and pro-inflammatory factors such as IL-6 and IL-10 are elevated in the plasma of critically ill patients infected with SARS-CoV-2 [46,47], suggesting that cytokine release syndrome (CRS) is associated with disease severity.
T103 6921-7047 Sentence denotes In the aspect of immune response, HCQ/CQ therefore are likely to inhibit CRS, delaying the progression of COVID-19 (Figure 1).

LitCovid-sample-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T5 4963-4967 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-sample-Pubtator

Id Subject Object Predicate Lexical cue pubann:denotes
313 37-45 Disease denotes COVID-19 MESH:C000657245
322 1387-1391 Gene denotes ACE2 Gene:59272
323 1555-1558 Gene denotes p38 Gene:1432
324 1668-1673 Gene denotes CD154 Gene:959
325 1692-1695 Gene denotes CD4 Gene:920
326 1142-1146 Species denotes CoVs Tax:11118
327 1127-1129 Chemical denotes CQ MESH:D002738
328 1130-1133 Chemical denotes HCQ MESH:D006886
329 1266-1274 Disease denotes COVID-19 MESH:C000657245
350 270-301 Gene denotes angiotensin-converting enzyme 2 Gene:59272
351 303-307 Gene denotes ACE2 Gene:59272
352 440-444 Gene denotes ACE2 Gene:103231639
353 698-702 Gene denotes ACE2 Gene:59272
354 777-781 Gene denotes ACE2 Gene:59272
355 922-926 Gene denotes ACE2 Gene:59272
356 983-987 Gene denotes ACE2 Gene:59272
357 584-585 Gene denotes S Gene:43740568
358 127-128 Gene denotes S Gene:43740568
359 140-150 Species denotes SARS-CoV-2 Tax:2697049
360 612-620 Species denotes SARS-CoV Tax:694009
361 992-1000 Species denotes SARS CoV Tax:694009
362 488-498 Species denotes SARS-CoV-2 Tax:2697049
363 821-824 Species denotes CoV Tax:11118
364 434-436 Chemical denotes CQ MESH:D002738
365 517-519 Chemical denotes CQ MESH:D002738
366 704-706 Chemical denotes CQ MESH:D002738
367 837-839 Chemical denotes CQ MESH:D002738
368 840-843 Chemical denotes HCQ MESH:D006886
369 448-454 CellLine denotes VeroE6 CVCL:0574
394 2535-2539 Gene denotes ACE2 Gene:59272
395 2828-2847 Gene denotes quinone reductase 2 Gene:4835
396 2849-2852 Gene denotes QR2 Gene:4835
397 2659-2665 Gene denotes CQ/HCQ
398 2420-2428 Species denotes SARS-CoV Tax:694009
400 2510-2520 Species denotes SARS-CoV-2 Tax:2697049
401 2385-2394 Species denotes influenza Tax:11320
402 2758-2765 Species denotes SARSCoV Tax:694009
403 2937-2940 Species denotes CoV Tax:11118
404 2265-2276 Chemical denotes sialic acid MESH:D019158
405 2306-2318 Chemical denotes gangliosides MESH:D005732
406 2592-2604 Chemical denotes gangliosides MESH:D005732
407 2638-2649 Chemical denotes sialic acid MESH:D019158
408 2672-2684 Chemical denotes sialic acids MESH:D012794
409 2689-2701 Chemical denotes gangliosides MESH:D005732
410 2781-2793 Chemical denotes gangliosides MESH:D005732
411 2800-2802 Chemical denotes CQ MESH:D002738
412 2886-2898 Chemical denotes sialic acids MESH:D012794
413 2953-2955 Chemical denotes CQ MESH:D002738
414 2956-2959 Chemical denotes HCQ MESH:D006886
415 3020-3031 Chemical denotes sialic acid MESH:D019158
416 3036-3047 Chemical denotes ganglioside MESH:D005732
417 2217-2226 Disease denotes infection MESH:D007239
442 3452-3457 Gene denotes furin Gene:5045
443 3658-3669 Gene denotes cathepsin L Gene:1514
444 3978-3989 Gene denotes cathepsin L Gene:1514
445 4346-4352 Gene denotes CQ/HCQ
446 4101-4107 Gene denotes CQ/HCQ
447 4028-4029 Gene denotes S Gene:43740568
448 3113-3117 Species denotes CoVs Tax:11118
452 3843-3864 Species denotes mouse hepatitis virus Tax:11138
453 3907-3917 Species denotes SARS-CoV-2 Tax:2697049
454 4017-4027 Species denotes SARS-CoV-2 Tax:2697049
455 4122-4132 Species denotes SARS-CoV-2 Tax:2697049
456 4163-4173 Species denotes SARS-CoV-2 Tax:2697049
457 4302-4312 Species denotes SARS-CoV-2 Tax:2697049
458 3868-3873 Species denotes MHV-2 Tax:502106
459 4444-4447 Species denotes CoV Tax:11118
460 3529-3535 Chemical denotes serine MESH:D012694
461 4269-4271 Chemical denotes CQ MESH:D002738
462 4460-4462 Chemical denotes CQ MESH:D002738
463 4463-4466 Chemical denotes HCQ MESH:D006886
464 3764-3778 Disease denotes CoV S proteins MESH:C000657245
465 4227-4233 CellLine denotes VeroE6 CVCL:0574
478 5273-5306 Gene denotes mitochondrial antiviral signaling Gene:57506
479 5308-5312 Gene denotes MAVS Gene:57506
480 4864-4868 Species denotes CoVs Tax:11118
482 4922-4931 Species denotes HCoV-229E Tax:11137
483 4947-4952 Species denotes human Tax:9606
484 5055-5058 Chemical denotes HCQ MESH:D006886
485 5108-5131 Chemical denotes reactive oxygen species MESH:D017382
486 5133-5136 Chemical denotes ROS MESH:D017382
487 5211-5214 Chemical denotes HCQ MESH:D006886
488 5380-5386 Chemical denotes CQ/HCQ
489 4851-4860 Disease denotes infection MESH:D007239
520 5956-5961 Gene denotes CD154 Gene:959
521 5980-5983 Gene denotes CD4 Gene:920
522 6034-6052 Gene denotes interleukin (IL)-1 Gene:3552
523 6054-6058 Gene denotes IL-6 Gene:3569
524 6063-6086 Gene denotes tumor necrosis factor-α Gene:7124
525 6088-6093 Gene denotes TNF-α Gene:7124
526 6238-6242 Gene denotes TLR7 Gene:51284
527 6247-6251 Gene denotes TLR9 Gene:54106
528 6347-6378 Gene denotes cyclic GMP-AMP (cGAMP) synthase Gene:115004
529 6380-6384 Gene denotes cGAS Gene:115004
530 6510-6526 Gene denotes phospholipase A2 Gene:5319
531 6733-6737 Gene denotes IL-6 Gene:3569
532 6742-6747 Gene denotes IL-10 Gene:3586
533 6793-6801 Species denotes patients Tax:9606
534 6816-6826 Species denotes SARS-CoV-2 Tax:2697049
535 5735-5737 Chemical denotes CQ MESH:D002738
536 5738-5741 Chemical denotes HCQ MESH:D006886
537 6000-6002 Chemical denotes CQ MESH:D002738
538 6324-6327 Chemical denotes CQ/ MESH:D002738
539 6327-6330 Chemical denotes HCQ MESH:D006886
540 6486-6492 Chemical denotes CQ/HCQ
541 6555-6571 Chemical denotes arachidonic acid MESH:D016718
542 6604-6618 Chemical denotes prostaglandins MESH:D011453
543 6955-6958 Chemical denotes HCQ MESH:D006886
544 6959-6961 Chemical denotes CQ MESH:D002738
545 6778-6792 Disease denotes critically ill MESH:D016638
546 6802-6810 Disease denotes infected MESH:D007239
547 6879-6882 Disease denotes CRS MESH:D003398
548 6994-6997 Disease denotes CRS MESH:D003398
549 7027-7035 Disease denotes COVID-19 MESH:C000657245

LitCovid-sample-UniProt

Id Subject Object Predicate Lexical cue uniprot_id
T1 127-136 Protein denotes S protein https://www.uniprot.org/uniprot/Q9UIP0|https://www.uniprot.org/uniprot/Q9UIN9|https://www.uniprot.org/uniprot/Q9UIN8|https://www.uniprot.org/uniprot/Q9UIN7|https://www.uniprot.org/uniprot/Q9UIN6|https://www.uniprot.org/uniprot/Q9UBH8|https://www.uniprot.org/uniprot/Q9NRH8|https://www.uniprot.org/uniprot/Q9NRH7|https://www.uniprot.org/uniprot/Q9NRH6|https://www.uniprot.org/uniprot/Q9NRH5|https://www.uniprot.org/uniprot/Q9NRH4|https://www.uniprot.org/uniprot/Q9NPG5|https://www.uniprot.org/uniprot/Q9NPE0|https://www.uniprot.org/uniprot/Q9NP52|https://www.uniprot.org/uniprot/Q95IF9|https://www.uniprot.org/uniprot/Q8N5P3|https://www.uniprot.org/uniprot/Q8IZU6|https://www.uniprot.org/uniprot/Q8IZU5|https://www.uniprot.org/uniprot/Q8IZU4|https://www.uniprot.org/uniprot/Q86Z04|https://www.uniprot.org/uniprot/Q7YR44|https://www.uniprot.org/uniprot/Q7LA71|https://www.uniprot.org/uniprot/Q7LA70|https://www.uniprot.org/uniprot/Q5STD2|https://www.uniprot.org/uniprot/Q5SQ85|https://www.uniprot.org/uniprot/Q1XI16|https://www.uniprot.org/uniprot/Q1XI12|https://www.uniprot.org/uniprot/Q15517|https://www.uniprot.org/uniprot/O43509|https://www.uniprot.org/uniprot/O19084|https://www.uniprot.org/uniprot/B0UYZ7|https://www.uniprot.org/uniprot/B0S7V2|https://www.uniprot.org/uniprot/A5A6L9
T34 270-301 Protein denotes angiotensin-converting enzyme 2 https://www.uniprot.org/uniprot/Q9UFZ6|https://www.uniprot.org/uniprot/Q9NRA7|https://www.uniprot.org/uniprot/Q9BYF1|https://www.uniprot.org/uniprot/Q99N71|https://www.uniprot.org/uniprot/Q99N70|https://www.uniprot.org/uniprot/Q8R0I0|https://www.uniprot.org/uniprot/Q86WT0|https://www.uniprot.org/uniprot/Q6UWP0|https://www.uniprot.org/uniprot/Q5RFN1|https://www.uniprot.org/uniprot/Q5EGZ1|https://www.uniprot.org/uniprot/Q58DD0|https://www.uniprot.org/uniprot/Q56NL1|https://www.uniprot.org/uniprot/Q56H28|https://www.uniprot.org/uniprot/Q2PGE2|https://www.uniprot.org/uniprot/C7ECU1
T49 303-307 Protein denotes ACE2 https://www.uniprot.org/uniprot/Q9UFZ6
T50 440-444 Protein denotes ACE2 https://www.uniprot.org/uniprot/Q9UFZ6
T51 584-593 Protein denotes S protein https://www.uniprot.org/uniprot/Q9UIP0|https://www.uniprot.org/uniprot/Q9UIN9|https://www.uniprot.org/uniprot/Q9UIN8|https://www.uniprot.org/uniprot/Q9UIN7|https://www.uniprot.org/uniprot/Q9UIN6|https://www.uniprot.org/uniprot/Q9UBH8|https://www.uniprot.org/uniprot/Q9NRH8|https://www.uniprot.org/uniprot/Q9NRH7|https://www.uniprot.org/uniprot/Q9NRH6|https://www.uniprot.org/uniprot/Q9NRH5|https://www.uniprot.org/uniprot/Q9NRH4|https://www.uniprot.org/uniprot/Q9NPG5|https://www.uniprot.org/uniprot/Q9NPE0|https://www.uniprot.org/uniprot/Q9NP52|https://www.uniprot.org/uniprot/Q95IF9|https://www.uniprot.org/uniprot/Q8N5P3|https://www.uniprot.org/uniprot/Q8IZU6|https://www.uniprot.org/uniprot/Q8IZU5|https://www.uniprot.org/uniprot/Q8IZU4|https://www.uniprot.org/uniprot/Q86Z04|https://www.uniprot.org/uniprot/Q7YR44|https://www.uniprot.org/uniprot/Q7LA71|https://www.uniprot.org/uniprot/Q7LA70|https://www.uniprot.org/uniprot/Q5STD2|https://www.uniprot.org/uniprot/Q5SQ85|https://www.uniprot.org/uniprot/Q1XI16|https://www.uniprot.org/uniprot/Q1XI12|https://www.uniprot.org/uniprot/Q15517|https://www.uniprot.org/uniprot/O43509|https://www.uniprot.org/uniprot/O19084|https://www.uniprot.org/uniprot/B0UYZ7|https://www.uniprot.org/uniprot/B0S7V2|https://www.uniprot.org/uniprot/A5A6L9
T84 698-702 Protein denotes ACE2 https://www.uniprot.org/uniprot/Q9UFZ6
T85 777-781 Protein denotes ACE2 https://www.uniprot.org/uniprot/Q9UFZ6
T86 922-926 Protein denotes ACE2 https://www.uniprot.org/uniprot/Q9UFZ6
T87 983-987 Protein denotes ACE2 https://www.uniprot.org/uniprot/Q9UFZ6
T88 1001-1010 Protein denotes S protein https://www.uniprot.org/uniprot/Q9UIP0|https://www.uniprot.org/uniprot/Q9UIN9|https://www.uniprot.org/uniprot/Q9UIN8|https://www.uniprot.org/uniprot/Q9UIN7|https://www.uniprot.org/uniprot/Q9UIN6|https://www.uniprot.org/uniprot/Q9UBH8|https://www.uniprot.org/uniprot/Q9NRH8|https://www.uniprot.org/uniprot/Q9NRH7|https://www.uniprot.org/uniprot/Q9NRH6|https://www.uniprot.org/uniprot/Q9NRH5|https://www.uniprot.org/uniprot/Q9NRH4|https://www.uniprot.org/uniprot/Q9NPG5|https://www.uniprot.org/uniprot/Q9NPE0|https://www.uniprot.org/uniprot/Q9NP52|https://www.uniprot.org/uniprot/Q95IF9|https://www.uniprot.org/uniprot/Q8N5P3|https://www.uniprot.org/uniprot/Q8IZU6|https://www.uniprot.org/uniprot/Q8IZU5|https://www.uniprot.org/uniprot/Q8IZU4|https://www.uniprot.org/uniprot/Q86Z04|https://www.uniprot.org/uniprot/Q7YR44|https://www.uniprot.org/uniprot/Q7LA71|https://www.uniprot.org/uniprot/Q7LA70|https://www.uniprot.org/uniprot/Q5STD2|https://www.uniprot.org/uniprot/Q5SQ85|https://www.uniprot.org/uniprot/Q1XI16|https://www.uniprot.org/uniprot/Q1XI12|https://www.uniprot.org/uniprot/Q15517|https://www.uniprot.org/uniprot/O43509|https://www.uniprot.org/uniprot/O19084|https://www.uniprot.org/uniprot/B0UYZ7|https://www.uniprot.org/uniprot/B0S7V2|https://www.uniprot.org/uniprot/A5A6L9
T121 1387-1391 Protein denotes ACE2 https://www.uniprot.org/uniprot/Q9UFZ6
T122 1396-1405 Protein denotes S protein https://www.uniprot.org/uniprot/Q9UIP0|https://www.uniprot.org/uniprot/Q9UIN9|https://www.uniprot.org/uniprot/Q9UIN8|https://www.uniprot.org/uniprot/Q9UIN7|https://www.uniprot.org/uniprot/Q9UIN6|https://www.uniprot.org/uniprot/Q9UBH8|https://www.uniprot.org/uniprot/Q9NRH8|https://www.uniprot.org/uniprot/Q9NRH7|https://www.uniprot.org/uniprot/Q9NRH6|https://www.uniprot.org/uniprot/Q9NRH5|https://www.uniprot.org/uniprot/Q9NRH4|https://www.uniprot.org/uniprot/Q9NPG5|https://www.uniprot.org/uniprot/Q9NPE0|https://www.uniprot.org/uniprot/Q9NP52|https://www.uniprot.org/uniprot/Q95IF9|https://www.uniprot.org/uniprot/Q8N5P3|https://www.uniprot.org/uniprot/Q8IZU6|https://www.uniprot.org/uniprot/Q8IZU5|https://www.uniprot.org/uniprot/Q8IZU4|https://www.uniprot.org/uniprot/Q86Z04|https://www.uniprot.org/uniprot/Q7YR44|https://www.uniprot.org/uniprot/Q7LA71|https://www.uniprot.org/uniprot/Q7LA70|https://www.uniprot.org/uniprot/Q5STD2|https://www.uniprot.org/uniprot/Q5SQ85|https://www.uniprot.org/uniprot/Q1XI16|https://www.uniprot.org/uniprot/Q1XI12|https://www.uniprot.org/uniprot/Q15517|https://www.uniprot.org/uniprot/O43509|https://www.uniprot.org/uniprot/O19084|https://www.uniprot.org/uniprot/B0UYZ7|https://www.uniprot.org/uniprot/B0S7V2|https://www.uniprot.org/uniprot/A5A6L9
T155 1555-1558 Protein denotes p38 https://www.uniprot.org/uniprot/Q9Y4Y1|https://www.uniprot.org/uniprot/Q9Y2S7|https://www.uniprot.org/uniprot/Q9UFX6|https://www.uniprot.org/uniprot/Q9UFG0|https://www.uniprot.org/uniprot/Q9Q6X7|https://www.uniprot.org/uniprot/Q9PY95|https://www.uniprot.org/uniprot/Q9P060|https://www.uniprot.org/uniprot/Q9NV58|https://www.uniprot.org/uniprot/Q9H8M8|https://www.uniprot.org/uniprot/Q9H5H9|https://www.uniprot.org/uniprot/Q96JE4|https://www.uniprot.org/uniprot/Q96IL6|https://www.uniprot.org/uniprot/Q96HJ0|https://www.uniprot.org/uniprot/Q96GA9|https://www.uniprot.org/uniprot/Q7TD18|https://www.uniprot.org/uniprot/Q64010|https://www.uniprot.org/uniprot/Q63768|https://www.uniprot.org/uniprot/Q52LG1|https://www.uniprot.org/uniprot/Q04929|https://www.uniprot.org/uniprot/Q01552|https://www.uniprot.org/uniprot/P46108|https://www.uniprot.org/uniprot/P34717|https://www.uniprot.org/uniprot/P27586|https://www.uniprot.org/uniprot/P0C797|https://www.uniprot.org/uniprot/P0C796|https://www.uniprot.org/uniprot/P06663|https://www.uniprot.org/uniprot/P04383|https://www.uniprot.org/uniprot/O97628|https://www.uniprot.org/uniprot/O95433|https://www.uniprot.org/uniprot/D3DTH6|https://www.uniprot.org/uniprot/B4DUR9|https://www.uniprot.org/uniprot/B2R9L2|https://www.uniprot.org/uniprot/B2R846|https://www.uniprot.org/uniprot/B0LPE8|https://www.uniprot.org/uniprot/A8MWE8|https://www.uniprot.org/uniprot/A3KCU9
T191 1668-1673 Protein denotes CD154 https://www.uniprot.org/uniprot/Q9Z2V2|https://www.uniprot.org/uniprot/Q9R254|https://www.uniprot.org/uniprot/Q9BDN3|https://www.uniprot.org/uniprot/Q9BDM7|https://www.uniprot.org/uniprot/Q9BDM3|https://www.uniprot.org/uniprot/Q9BDC7|https://www.uniprot.org/uniprot/Q95MQ5|https://www.uniprot.org/uniprot/P63305|https://www.uniprot.org/uniprot/P63304|https://www.uniprot.org/uniprot/P51749|https://www.uniprot.org/uniprot/P29965|https://www.uniprot.org/uniprot/P27548|https://www.uniprot.org/uniprot/O97626|https://www.uniprot.org/uniprot/O97605
T205 1692-1695 Protein denotes CD4 https://www.uniprot.org/uniprot/Q9XS78|https://www.uniprot.org/uniprot/Q9UDE5|https://www.uniprot.org/uniprot/Q5U066|https://www.uniprot.org/uniprot/Q4ZGK2|https://www.uniprot.org/uniprot/Q29617|https://www.uniprot.org/uniprot/Q29037|https://www.uniprot.org/uniprot/Q28217|https://www.uniprot.org/uniprot/Q08340|https://www.uniprot.org/uniprot/Q08339|https://www.uniprot.org/uniprot/Q08338|https://www.uniprot.org/uniprot/Q08336|https://www.uniprot.org/uniprot/P79196|https://www.uniprot.org/uniprot/P79185|https://www.uniprot.org/uniprot/P79184|https://www.uniprot.org/uniprot/P46630|https://www.uniprot.org/uniprot/P33705|https://www.uniprot.org/uniprot/P16004|https://www.uniprot.org/uniprot/P16003|https://www.uniprot.org/uniprot/P06332|https://www.uniprot.org/uniprot/P05542|https://www.uniprot.org/uniprot/P05540|https://www.uniprot.org/uniprot/P01730|https://www.uniprot.org/uniprot/O77593|https://www.uniprot.org/uniprot/O02805|https://www.uniprot.org/uniprot/D3DUS5|https://www.uniprot.org/uniprot/B2R737
T231 1823-1827 Protein denotes ACE2 https://www.uniprot.org/uniprot/Q9UFZ6
T232 1829-1860 Protein denotes angiotensin-converting enzyme 2 https://www.uniprot.org/uniprot/Q9UFZ6|https://www.uniprot.org/uniprot/Q9NRA7|https://www.uniprot.org/uniprot/Q9BYF1|https://www.uniprot.org/uniprot/Q99N71|https://www.uniprot.org/uniprot/Q99N70|https://www.uniprot.org/uniprot/Q8R0I0|https://www.uniprot.org/uniprot/Q86WT0|https://www.uniprot.org/uniprot/Q6UWP0|https://www.uniprot.org/uniprot/Q5RFN1|https://www.uniprot.org/uniprot/Q5EGZ1|https://www.uniprot.org/uniprot/Q58DD0|https://www.uniprot.org/uniprot/Q56NL1|https://www.uniprot.org/uniprot/Q56H28|https://www.uniprot.org/uniprot/Q2PGE2|https://www.uniprot.org/uniprot/C7ECU1
T247 2077-2081 Protein denotes cGAS https://www.uniprot.org/uniprot/Q96E45|https://www.uniprot.org/uniprot/Q8N884|https://www.uniprot.org/uniprot/Q8C6L5|https://www.uniprot.org/uniprot/Q5SWL1|https://www.uniprot.org/uniprot/Q5SWL0|https://www.uniprot.org/uniprot/Q3ULW3|https://www.uniprot.org/uniprot/Q32NC9|https://www.uniprot.org/uniprot/Q14CV6|https://www.uniprot.org/uniprot/L0L2J9|https://www.uniprot.org/uniprot/I3LM39|https://www.uniprot.org/uniprot/E1BGN7|https://www.uniprot.org/uniprot/A7SFB5
T259 2083-2106 Protein denotes cyclic GMP-AMP synthase https://www.uniprot.org/uniprot/Q96E45|https://www.uniprot.org/uniprot/Q8N884|https://www.uniprot.org/uniprot/Q8C6L5|https://www.uniprot.org/uniprot/Q5SWL1|https://www.uniprot.org/uniprot/Q5SWL0|https://www.uniprot.org/uniprot/Q3ULW3|https://www.uniprot.org/uniprot/Q32NC9|https://www.uniprot.org/uniprot/Q14CV6|https://www.uniprot.org/uniprot/L0L2J9|https://www.uniprot.org/uniprot/I3LM39|https://www.uniprot.org/uniprot/E1BGN7|https://www.uniprot.org/uniprot/A7SFB5
T271 2113-2123 Protein denotes interferon https://www.uniprot.org/uniprot/P51527|https://www.uniprot.org/uniprot/P51526
T273 2149-2170 Protein denotes tumor necrosis factor https://www.uniprot.org/uniprot/Q9UIV3|https://www.uniprot.org/uniprot/Q9TTJ3|https://www.uniprot.org/uniprot/Q9P1Q2|https://www.uniprot.org/uniprot/Q9MYZ2|https://www.uniprot.org/uniprot/Q9JI27|https://www.uniprot.org/uniprot/Q9JI26|https://www.uniprot.org/uniprot/Q9BEA1|https://www.uniprot.org/uniprot/Q91VF3|https://www.uniprot.org/uniprot/Q8WNR1|https://www.uniprot.org/uniprot/Q8MKG8|https://www.uniprot.org/uniprot/Q8JFG3|https://www.uniprot.org/uniprot/Q8HZD9|https://www.uniprot.org/uniprot/Q8HZD6|https://www.uniprot.org/uniprot/Q8HYM0|https://www.uniprot.org/uniprot/Q75N23|https://www.uniprot.org/uniprot/Q6EE11|https://www.uniprot.org/uniprot/Q62326|https://www.uniprot.org/uniprot/Q5TM21|https://www.uniprot.org/uniprot/Q539C2|https://www.uniprot.org/uniprot/Q2MH05|https://www.uniprot.org/uniprot/P29553|https://www.uniprot.org/uniprot/P23563|https://www.uniprot.org/uniprot/P23383|https://www.uniprot.org/uniprot/P19101|https://www.uniprot.org/uniprot/P16599|https://www.uniprot.org/uniprot/P13296|https://www.uniprot.org/uniprot/P06804|https://www.uniprot.org/uniprot/P04924|https://www.uniprot.org/uniprot/P01375|https://www.uniprot.org/uniprot/O77764|https://www.uniprot.org/uniprot/O77510|https://www.uniprot.org/uniprot/O43647|https://www.uniprot.org/uniprot/O35853|https://www.uniprot.org/uniprot/O35734|https://www.uniprot.org/uniprot/O18779|https://www.uniprot.org/uniprot/A9QWR7|https://www.uniprot.org/uniprot/A5D9N8|https://www.uniprot.org/uniprot/A4IFT5|https://www.uniprot.org/uniprot/Q28339|https://www.uniprot.org/uniprot/Q28320|https://www.uniprot.org/uniprot/Q27978|https://www.uniprot.org/uniprot/Q1XHZ6|https://www.uniprot.org/uniprot/Q1WM27|https://www.uniprot.org/uniprot/Q1G1A2|https://www.uniprot.org/uniprot/Q19LH4|https://www.uniprot.org/uniprot/Q06599|https://www.uniprot.org/uniprot/Q006K5|https://www.uniprot.org/uniprot/P79374|https://www.uniprot.org/uniprot/P79337|https://www.uniprot.org/uniprot/P59695|https://www.uniprot.org/uniprot/P59694|https://www.uniprot.org/uniprot/P59693|https://www.uniprot.org/uniprot/P59684|https://www.uniprot.org/uniprot/P51743|https://www.uniprot.org/uniprot/P51742|https://www.uniprot.org/uniprot/P51435|https://www.uniprot.org/uniprot/P48094|https://www.uniprot.org/uniprot/P36939|https://www.uniprot.org/uniprot/P33620
T332 2288-2301 Protein denotes glycoproteins https://www.uniprot.org/uniprot/Q9QSP1|https://www.uniprot.org/uniprot/Q9QJT6|https://www.uniprot.org/uniprot/Q9JGT4|https://www.uniprot.org/uniprot/Q9IPJ6|https://www.uniprot.org/uniprot/Q9DIC6|https://www.uniprot.org/uniprot/Q91DS0|https://www.uniprot.org/uniprot/Q91C28|https://www.uniprot.org/uniprot/Q8QQA2|https://www.uniprot.org/uniprot/Q8QPE5|https://www.uniprot.org/uniprot/Q8QPE4|https://www.uniprot.org/uniprot/Q8QPE3|https://www.uniprot.org/uniprot/Q8JTH0|https://www.uniprot.org/uniprot/Q8BDV6|https://www.uniprot.org/uniprot/Q8B6J6|https://www.uniprot.org/uniprot/Q8B0I1|https://www.uniprot.org/uniprot/Q8B0H6|https://www.uniprot.org/uniprot/Q8B0H1|https://www.uniprot.org/uniprot/Q89669|https://www.uniprot.org/uniprot/Q85213|https://www.uniprot.org/uniprot/Q82706|https://www.uniprot.org/uniprot/Q82683|https://www.uniprot.org/uniprot/Q82020|https://www.uniprot.org/uniprot/Q787B5|https://www.uniprot.org/uniprot/Q77SK0|https://www.uniprot.org/uniprot/Q77N36|https://www.uniprot.org/uniprot/Q76G52|https://www.uniprot.org/uniprot/Q75T09|https://www.uniprot.org/uniprot/Q6X1D5|https://www.uniprot.org/uniprot/Q6X1D1|https://www.uniprot.org/uniprot/Q6TYA0|https://www.uniprot.org/uniprot/Q6E0W7|https://www.uniprot.org/uniprot/Q66T62|https://www.uniprot.org/uniprot/Q5VKP3|https://www.uniprot.org/uniprot/Q5VKN9|https://www.uniprot.org/uniprot/Q5K2K4|https://www.uniprot.org/uniprot/Q5IX93|https://www.uniprot.org/uniprot/Q5IX92|https://www.uniprot.org/uniprot/Q5IX91|https://www.uniprot.org/uniprot/Q5IX90|https://www.uniprot.org/uniprot/Q5IX89|https://www.uniprot.org/uniprot/Q5IX88|https://www.uniprot.org/uniprot/Q5IX87|https://www.uniprot.org/uniprot/Q5GA86|https://www.uniprot.org/uniprot/Q58FH1|https://www.uniprot.org/uniprot/Q4VKV3|https://www.uniprot.org/uniprot/Q4F900|https://www.uniprot.org/uniprot/Q49LL3|https://www.uniprot.org/uniprot/Q49IU2|https://www.uniprot.org/uniprot/Q49IU1|https://www.uniprot.org/uniprot/Q49IT9|https://www.uniprot.org/uniprot/Q49IT8|https://www.uniprot.org/uniprot/Q49AV0|https://www.uniprot.org/uniprot/Q0GBY1|https://www.uniprot.org/uniprot/Q0GBX6|https://www.uniprot.org/uniprot/Q08089|https://www.uniprot.org/uniprot/P32595|https://www.uniprot.org/uniprot/P32550|https://www.uniprot.org/uniprot/P19462|https://www.uniprot.org/uniprot/P16288|https://www.uniprot.org/uniprot/P15199|https://www.uniprot.org/uniprot/P13180|https://www.uniprot.org/uniprot/P0C572|https://www.uniprot.org/uniprot/P08667|https://www.uniprot.org/uniprot/P08163|https://www.uniprot.org/uniprot/P07923|https://www.uniprot.org/uniprot/P04884|https://www.uniprot.org/uniprot/P04883|https://www.uniprot.org/uniprot/P04882|https://www.uniprot.org/uniprot/P03524|https://www.uniprot.org/uniprot/P03522|https://www.uniprot.org/uniprot/O92284|https://www.uniprot.org/uniprot/O56677|https://www.uniprot.org/uniprot/O10236|https://www.uniprot.org/uniprot/J7HBH4|https://www.uniprot.org/uniprot/D8V075|https://www.uniprot.org/uniprot/A7WNB3|https://www.uniprot.org/uniprot/A4UHQ6|https://www.uniprot.org/uniprot/A4UHQ1|https://www.uniprot.org/uniprot/A3RM22|https://www.uniprot.org/uniprot/A3F5R8|https://www.uniprot.org/uniprot/A3F5R3|https://www.uniprot.org/uniprot/A3F5Q8|https://www.uniprot.org/uniprot/A3F5N3|https://www.uniprot.org/uniprot/A3F5M3|https://www.uniprot.org/uniprot/A3F5L8
T417 2535-2539 Protein denotes ACE2 https://www.uniprot.org/uniprot/Q9UFZ6
T418 2768-2777 Protein denotes S protein https://www.uniprot.org/uniprot/Q9UIP0|https://www.uniprot.org/uniprot/Q9UIN9|https://www.uniprot.org/uniprot/Q9UIN8|https://www.uniprot.org/uniprot/Q9UIN7|https://www.uniprot.org/uniprot/Q9UIN6|https://www.uniprot.org/uniprot/Q9UBH8|https://www.uniprot.org/uniprot/Q9NRH8|https://www.uniprot.org/uniprot/Q9NRH7|https://www.uniprot.org/uniprot/Q9NRH6|https://www.uniprot.org/uniprot/Q9NRH5|https://www.uniprot.org/uniprot/Q9NRH4|https://www.uniprot.org/uniprot/Q9NPG5|https://www.uniprot.org/uniprot/Q9NPE0|https://www.uniprot.org/uniprot/Q9NP52|https://www.uniprot.org/uniprot/Q95IF9|https://www.uniprot.org/uniprot/Q8N5P3|https://www.uniprot.org/uniprot/Q8IZU6|https://www.uniprot.org/uniprot/Q8IZU5|https://www.uniprot.org/uniprot/Q8IZU4|https://www.uniprot.org/uniprot/Q86Z04|https://www.uniprot.org/uniprot/Q7YR44|https://www.uniprot.org/uniprot/Q7LA71|https://www.uniprot.org/uniprot/Q7LA70|https://www.uniprot.org/uniprot/Q5STD2|https://www.uniprot.org/uniprot/Q5SQ85|https://www.uniprot.org/uniprot/Q1XI16|https://www.uniprot.org/uniprot/Q1XI12|https://www.uniprot.org/uniprot/Q15517|https://www.uniprot.org/uniprot/O43509|https://www.uniprot.org/uniprot/O19084|https://www.uniprot.org/uniprot/B0UYZ7|https://www.uniprot.org/uniprot/B0S7V2|https://www.uniprot.org/uniprot/A5A6L9
T451 2828-2847 Protein denotes quinone reductase 2 https://www.uniprot.org/uniprot/Q9JI75|https://www.uniprot.org/uniprot/Q6AY80|https://www.uniprot.org/uniprot/Q5TD04|https://www.uniprot.org/uniprot/Q5RBB9|https://www.uniprot.org/uniprot/P16083|https://www.uniprot.org/uniprot/B2R492
T457 2849-2852 Protein denotes QR2 https://www.uniprot.org/uniprot/Q9JI75|https://www.uniprot.org/uniprot/Q6AY80|https://www.uniprot.org/uniprot/Q5TD04|https://www.uniprot.org/uniprot/Q5RBB9|https://www.uniprot.org/uniprot/P16083|https://www.uniprot.org/uniprot/B2R492
T463 3443-3450 Protein denotes trypsin https://www.uniprot.org/uniprot/P83348|https://www.uniprot.org/uniprot/P81524|https://www.uniprot.org/uniprot/P81071|https://www.uniprot.org/uniprot/P70059|https://www.uniprot.org/uniprot/P51588|https://www.uniprot.org/uniprot/P35051|https://www.uniprot.org/uniprot/P35050|https://www.uniprot.org/uniprot/P35048|https://www.uniprot.org/uniprot/P35034|https://www.uniprot.org/uniprot/P19799|https://www.uniprot.org/uniprot/P00764|https://www.uniprot.org/uniprot/P00761|https://www.uniprot.org/uniprot/O97399
T476 3452-3457 Protein denotes furin https://www.uniprot.org/uniprot/Q9UCZ5|https://www.uniprot.org/uniprot/Q6LBS3|https://www.uniprot.org/uniprot/Q6GTN6|https://www.uniprot.org/uniprot/Q28193|https://www.uniprot.org/uniprot/Q14336|https://www.uniprot.org/uniprot/P23377|https://www.uniprot.org/uniprot/P23188|https://www.uniprot.org/uniprot/P09958
T484 3520-3528 Protein denotes protease https://www.uniprot.org/uniprot/Q9Y6I0|https://www.uniprot.org/uniprot/Q9WJC5|https://www.uniprot.org/uniprot/Q9WF19|https://www.uniprot.org/uniprot/Q9WC63|https://www.uniprot.org/uniprot/Q9WC54|https://www.uniprot.org/uniprot/Q9UKI1|https://www.uniprot.org/uniprot/Q9UKI0|https://www.uniprot.org/uniprot/Q9UKH6|https://www.uniprot.org/uniprot/Q9UKH5|https://www.uniprot.org/uniprot/P04323|https://www.uniprot.org/uniprot/P04023|https://www.uniprot.org/uniprot/P03371|https://www.uniprot.org/uniprot/P03370|https://www.uniprot.org/uniprot/P03369|https://www.uniprot.org/uniprot/P03368|https://www.uniprot.org/uniprot/P03367|https://www.uniprot.org/uniprot/P03366|https://www.uniprot.org/uniprot/P03365|https://www.uniprot.org/uniprot/P03363|https://www.uniprot.org/uniprot/P03362|https://www.uniprot.org/uniprot/P03361|https://www.uniprot.org/uniprot/P03360|https://www.uniprot.org/uniprot/P03359|https://www.uniprot.org/uniprot/P03357|https://www.uniprot.org/uniprot/P03356|https://www.uniprot.org/uniprot/P03355|https://www.uniprot.org/uniprot/P03353|https://www.uniprot.org/uniprot/P03253|https://www.uniprot.org/uniprot/P03252|https://www.uniprot.org/uniprot/P03234|https://www.uniprot.org/uniprot/O93215|https://www.uniprot.org/uniprot/O92808|https://www.uniprot.org/uniprot/O91080|https://www.uniprot.org/uniprot/O89940|https://www.uniprot.org/uniprot/O89811|https://www.uniprot.org/uniprot/O89290|https://www.uniprot.org/uniprot/O73194|https://www.uniprot.org/uniprot/O71150|https://www.uniprot.org/uniprot/O71070|https://www.uniprot.org/uniprot/O56228|https://www.uniprot.org/uniprot/O56227|https://www.uniprot.org/uniprot/O41798|https://www.uniprot.org/uniprot/O40958|https://www.uniprot.org/uniprot/O36367|https://www.uniprot.org/uniprot/O12158|https://www.uniprot.org/uniprot/O09798|https://www.uniprot.org/uniprot/O09777|https://www.uniprot.org/uniprot/D2K3N9|https://www.uniprot.org/uniprot/D2K3N8|https://www.uniprot.org/uniprot/D0UZM9|https://www.uniprot.org/uniprot/A0A0U3TYK5|https://www.uniprot.org/uniprot/A0A0A8IBU6|https://www.uniprot.org/uniprot/Q9UKH4|https://www.uniprot.org/uniprot/Q9QSR3|https://www.uniprot.org/uniprot/Q9QM72|https://www.uniprot.org/uniprot/Q9QJ30|https://www.uniprot.org/uniprot/Q9QBZ9|https://www.uniprot.org/uniprot/Q9QBZ5|https://www.uniprot.org/uniprot/Q9QBZ1|https://www.uniprot.org/uniprot/Q9QBY3|https://www.uniprot.org/uniprot/Q9Q720|https://www.uniprot.org/uniprot/Q9IZT3|https://www.uniprot.org/uniprot/Q9IZT2|https://www.uniprot.org/uniprot/Q9IRA3|https://www.uniprot.org/uniprot/Q9IIH4|https://www.uniprot.org/uniprot/Q9IDV9|https://www.uniprot.org/uniprot/Q9E6P2|https://www.uniprot.org/uniprot/Q9E6P1|https://www.uniprot.org/uniprot/Q96629|https://www.uniprot.org/uniprot/Q91QZ3|https://www.uniprot.org/uniprot/Q8JN66|https://www.uniprot.org/uniprot/Q8I7P9|https://www.uniprot.org/uniprot/Q8AII1|https://www.uniprot.org/uniprot/Q89928|https://www.uniprot.org/uniprot/Q89855|https://www.uniprot.org/uniprot/Q89703|https://www.uniprot.org/uniprot/Q89548|https://www.uniprot.org/uniprot/Q88140|https://www.uniprot.org/uniprot/Q85590|https://www.uniprot.org/uniprot/Q85571|https://www.uniprot.org/uniprot/Q85570|https://www.uniprot.org/uniprot/Q84177|https://www.uniprot.org/uniprot/Q83906|https://www.uniprot.org/uniprot/Q83417|https://www.uniprot.org/uniprot/Q82859|https://www.uniprot.org/uniprot/Q82851|https://www.uniprot.org/uniprot/Q7SVK7|https://www.uniprot.org/uniprot/Q7M6L1|https://www.uniprot.org/uniprot/Q7M6L0|https://www.uniprot.org/uniprot/Q79666|https://www.uniprot.org/uniprot/Q79582|https://www.uniprot.org/uniprot/Q77906|https://www.uniprot.org/uniprot/Q777B6|https://www.uniprot.org/uniprot/Q77373|https://www.uniprot.org/uniprot/Q76634|https://www.uniprot.org/uniprot/Q76629|https://www.uniprot.org/uniprot/Q76605|https://www.uniprot.org/uniprot/Q75002|https://www.uniprot.org/uniprot/Q74120|https://www.uniprot.org/uniprot/Q73368|https://www.uniprot.org/uniprot/Q6UDK6|https://www.uniprot.org/uniprot/Q6UDK5|https://www.uniprot.org/uniprot/Q6SW62|https://www.uniprot.org/uniprot/Q6SW61|https://www.uniprot.org/uniprot/Q6S6T7|https://www.uniprot.org/uniprot/Q6S6T6|https://www.uniprot.org/uniprot/Q69263|https://www.uniprot.org/uniprot/Q69030|https://www.uniprot.org/uniprot/Q66541|https://www.uniprot.org/uniprot/Q65ZF9|https://www.uniprot.org/uniprot/Q65652|https://www.uniprot.org/uniprot/Q65593|https://www.uniprot.org/uniprot/Q64962|https://www.uniprot.org/uniprot/Q61577|https://www.uniprot.org/uniprot/Q5TJ03|https://www.uniprot.org/uniprot/Q4U0X6|https://www.uniprot.org/uniprot/Q3KSP9|https://www.uniprot.org/uniprot/Q2Q1R2|https://www.uniprot.org/uniprot/Q2HRB6|https://www.uniprot.org/uniprot/Q2HRB5|https://www.uniprot.org/uniprot/Q27YG9|https://www.uniprot.org/uniprot/Q1HVC7|https://www.uniprot.org/uniprot/Q18LE3|https://www.uniprot.org/uniprot/Q0R5R3|https://www.uniprot.org/uniprot/Q0R5R2|https://www.uniprot.org/uniprot/Q09SZ9|https://www.uniprot.org/uniprot/Q02836|https://www.uniprot.org/uniprot/Q01002|https://www.uniprot.org/uniprot/P90341|https://www.uniprot.org/uniprot/P89449|https://www.uniprot.org/uniprot/P87563|https://www.uniprot.org/uniprot/P84454|https://www.uniprot.org/uniprot/P68986|https://www.uniprot.org/uniprot/P68985|https://www.uniprot.org/uniprot/P68984|https://www.uniprot.org/uniprot/P63131|https://www.uniprot.org/uniprot/P63129|https://www.uniprot.org/uniprot/P63128|https://www.uniprot.org/uniprot/P63127|https://www.uniprot.org/uniprot/P63125|https://www.uniprot.org/uniprot/P63124|https://www.uniprot.org/uniprot/P63123|https://www.uniprot.org/uniprot/P63122|https://www.uniprot.org/uniprot/P63121|https://www.uniprot.org/uniprot/P63120|https://www.uniprot.org/uniprot/P63119|https://www.uniprot.org/uniprot/P54817|https://www.uniprot.org/uniprot/P52369|https://www.uniprot.org/uniprot/P52351|https://www.uniprot.org/uniprot/P42672|https://www.uniprot.org/uniprot/P35990|https://www.uniprot.org/uniprot/P35963|https://www.uniprot.org/uniprot/P35956|https://www.uniprot.org/uniprot/P33459|https://www.uniprot.org/uniprot/P32542|https://www.uniprot.org/uniprot/P31822|https://www.uniprot.org/uniprot/P30202|https://www.uniprot.org/uniprot/P28936|https://www.uniprot.org/uniprot/P27980|https://www.uniprot.org/uniprot/P27973|https://www.uniprot.org/uniprot/P27528|https://www.uniprot.org/uniprot/P27502|https://www.uniprot.org/uniprot/P26810|https://www.uniprot.org/uniprot/P26809|https://www.uniprot.org/uniprot/P26808|https://www.uniprot.org/uniprot/P25059|https://www.uniprot.org/uniprot/P24740|https://www.uniprot.org/uniprot/P24433|https://www.uniprot.org/uniprot/P24107|https://www.uniprot.org/uniprot/P23984|https://www.uniprot.org/uniprot/P23427|https://www.uniprot.org/uniprot/P23426|https://www.uniprot.org/uniprot/P22382|https://www.uniprot.org/uniprot/P21414|https://www.uniprot.org/uniprot/P20892|https://www.uniprot.org/uniprot/P20876|https://www.uniprot.org/uniprot/P20875|https://www.uniprot.org/uniprot/P20825|https://www.uniprot.org/uniprot/P19561|https://www.uniprot.org/uniprot/P19560|https://www.uniprot.org/uniprot/P19505|https://www.uniprot.org/uniprot/P19202|https://www.uniprot.org/uniprot/P19199|https://www.uniprot.org/uniprot/P19151|https://www.uniprot.org/uniprot/P19119|https://www.uniprot.org/uniprot/P19028|https://www.uniprot.org/uniprot/P18802|https://www.uniprot.org/uniprot/P18096|https://www.uniprot.org/uniprot/P18042|https://www.uniprot.org/uniprot/P17965|https://www.uniprot.org/uniprot/P17757|https://www.uniprot.org/uniprot/P17283|https://www.uniprot.org/uniprot/P16901|https://www.uniprot.org/uniprot/P16753|https://www.uniprot.org/uniprot/P16423|https://www.uniprot.org/uniprot/P16088|https://www.uniprot.org/uniprot/P16046|https://www.uniprot.org/uniprot/P15833|https://www.uniprot.org/uniprot/P14078|https://www.uniprot.org/uniprot/P14074|https://www.uniprot.org/uniprot/P12502|https://www.uniprot.org/uniprot/P12499|https://www.uniprot.org/uniprot/P12498|https://www.uniprot.org/uniprot/P12497|https://www.uniprot.org/uniprot/P12451|https://www.uniprot.org/uniprot/P11826|https://www.uniprot.org/uniprot/P11825|https://www.uniprot.org/uniprot/P11365|https://www.uniprot.org/uniprot/P11283|https://www.uniprot.org/uniprot/P11227|https://www.uniprot.org/uniprot/P11204|https://www.uniprot.org/uniprot/P10394|https://www.uniprot.org/uniprot/P10381|https://www.uniprot.org/uniprot/P10274|https://www.uniprot.org/uniprot/P10273|https://www.uniprot.org/uniprot/P10272|https://www.uniprot.org/uniprot/P10271|https://www.uniprot.org/uniprot/P10270|https://www.uniprot.org/uniprot/P10265|https://www.uniprot.org/uniprot/P10210|https://www.uniprot.org/uniprot/P0DOI1|https://www.uniprot.org/uniprot/P0DOI0|https://www.uniprot.org/uniprot/P0C6F2|https://www.uniprot.org/uniprot/P0C211|https://www.uniprot.org/uniprot/P0C210|https://www.uniprot.org/uniprot/P09569|https://www.uniprot.org/uniprot/P09286|https://www.uniprot.org/uniprot/P08361|https://www.uniprot.org/uniprot/P07885|https://www.uniprot.org/uniprot/P05962|https://www.uniprot.org/uniprot/P05961|https://www.uniprot.org/uniprot/P05960|https://www.uniprot.org/uniprot/P05959|https://www.uniprot.org/uniprot/P05897|https://www.uniprot.org/uniprot/P05896|https://www.uniprot.org/uniprot/P05895|https://www.uniprot.org/uniprot/P04589|https://www.uniprot.org/uniprot/P04588|https://www.uniprot.org/uniprot/P04587|https://www.uniprot.org/uniprot/P04585|https://www.uniprot.org/uniprot/P04584|https://www.uniprot.org/uniprot/Q1HVC6|https://www.uniprot.org/uniprot/Q1A267|https://www.uniprot.org/uniprot/Q1A249
T728 3559-3567 Protein denotes elastase https://www.uniprot.org/uniprot/P32197
T729 3585-3594 Protein denotes S protein https://www.uniprot.org/uniprot/Q9UIP0|https://www.uniprot.org/uniprot/Q9UIN9|https://www.uniprot.org/uniprot/Q9UIN8|https://www.uniprot.org/uniprot/Q9UIN7|https://www.uniprot.org/uniprot/Q9UIN6|https://www.uniprot.org/uniprot/Q9UBH8|https://www.uniprot.org/uniprot/Q9NRH8|https://www.uniprot.org/uniprot/Q9NRH7|https://www.uniprot.org/uniprot/Q9NRH6|https://www.uniprot.org/uniprot/Q9NRH5|https://www.uniprot.org/uniprot/Q9NRH4|https://www.uniprot.org/uniprot/Q9NPG5|https://www.uniprot.org/uniprot/Q9NPE0|https://www.uniprot.org/uniprot/Q9NP52|https://www.uniprot.org/uniprot/Q95IF9|https://www.uniprot.org/uniprot/Q8N5P3|https://www.uniprot.org/uniprot/Q8IZU6|https://www.uniprot.org/uniprot/Q8IZU5|https://www.uniprot.org/uniprot/Q8IZU4|https://www.uniprot.org/uniprot/Q86Z04|https://www.uniprot.org/uniprot/Q7YR44|https://www.uniprot.org/uniprot/Q7LA71|https://www.uniprot.org/uniprot/Q7LA70|https://www.uniprot.org/uniprot/Q5STD2|https://www.uniprot.org/uniprot/Q5SQ85|https://www.uniprot.org/uniprot/Q1XI16|https://www.uniprot.org/uniprot/Q1XI12|https://www.uniprot.org/uniprot/Q15517|https://www.uniprot.org/uniprot/O43509|https://www.uniprot.org/uniprot/O19084|https://www.uniprot.org/uniprot/B0UYZ7|https://www.uniprot.org/uniprot/B0S7V2|https://www.uniprot.org/uniprot/A5A6L9
T762 3658-3669 Protein denotes cathepsin L https://www.uniprot.org/uniprot/Q9QV07|https://www.uniprot.org/uniprot/Q9GL24|https://www.uniprot.org/uniprot/Q9GKL8|https://www.uniprot.org/uniprot/Q96QJ0|https://www.uniprot.org/uniprot/Q95029|https://www.uniprot.org/uniprot/Q91UZ0|https://www.uniprot.org/uniprot/Q6IAV1|https://www.uniprot.org/uniprot/Q5U121|https://www.uniprot.org/uniprot/Q3T0P2|https://www.uniprot.org/uniprot/Q28944|https://www.uniprot.org/uniprot/Q26636|https://www.uniprot.org/uniprot/Q26534|https://www.uniprot.org/uniprot/Q10991|https://www.uniprot.org/uniprot/P25975|https://www.uniprot.org/uniprot/P25773|https://www.uniprot.org/uniprot/P09648|https://www.uniprot.org/uniprot/P07711|https://www.uniprot.org/uniprot/P07154|https://www.uniprot.org/uniprot/P06797|https://www.uniprot.org/uniprot/O97431|https://www.uniprot.org/uniprot/O77502|https://www.uniprot.org/uniprot/M3WXJ1
T784 3768-3778 Protein denotes S proteins https://www.uniprot.org/uniprot/Q9UIP0|https://www.uniprot.org/uniprot/Q9UIN9|https://www.uniprot.org/uniprot/Q9UIN8|https://www.uniprot.org/uniprot/Q9UIN7|https://www.uniprot.org/uniprot/Q9UIN6|https://www.uniprot.org/uniprot/Q9UBH8|https://www.uniprot.org/uniprot/Q9NRH8|https://www.uniprot.org/uniprot/Q9NRH7|https://www.uniprot.org/uniprot/Q9NRH6|https://www.uniprot.org/uniprot/Q9NRH5|https://www.uniprot.org/uniprot/Q9NRH4|https://www.uniprot.org/uniprot/Q9NPG5|https://www.uniprot.org/uniprot/Q9NPE0|https://www.uniprot.org/uniprot/Q9NP52|https://www.uniprot.org/uniprot/Q95IF9|https://www.uniprot.org/uniprot/Q8N5P3|https://www.uniprot.org/uniprot/Q8IZU6|https://www.uniprot.org/uniprot/Q8IZU5|https://www.uniprot.org/uniprot/Q8IZU4|https://www.uniprot.org/uniprot/Q86Z04|https://www.uniprot.org/uniprot/Q7YR44|https://www.uniprot.org/uniprot/Q7LA71|https://www.uniprot.org/uniprot/Q7LA70|https://www.uniprot.org/uniprot/Q5STD2|https://www.uniprot.org/uniprot/Q5SQ85|https://www.uniprot.org/uniprot/Q1XI16|https://www.uniprot.org/uniprot/Q1XI12|https://www.uniprot.org/uniprot/Q15517|https://www.uniprot.org/uniprot/O43509|https://www.uniprot.org/uniprot/O19084|https://www.uniprot.org/uniprot/B0UYZ7|https://www.uniprot.org/uniprot/B0S7V2|https://www.uniprot.org/uniprot/A5A6L9
T817 3978-3989 Protein denotes cathepsin L https://www.uniprot.org/uniprot/Q9QV07|https://www.uniprot.org/uniprot/Q9GL24|https://www.uniprot.org/uniprot/Q9GKL8|https://www.uniprot.org/uniprot/Q96QJ0|https://www.uniprot.org/uniprot/Q95029|https://www.uniprot.org/uniprot/Q91UZ0|https://www.uniprot.org/uniprot/Q6IAV1|https://www.uniprot.org/uniprot/Q5U121|https://www.uniprot.org/uniprot/Q3T0P2|https://www.uniprot.org/uniprot/Q28944|https://www.uniprot.org/uniprot/Q26636|https://www.uniprot.org/uniprot/Q26534|https://www.uniprot.org/uniprot/Q10991|https://www.uniprot.org/uniprot/P25975|https://www.uniprot.org/uniprot/P25773|https://www.uniprot.org/uniprot/P09648|https://www.uniprot.org/uniprot/P07711|https://www.uniprot.org/uniprot/P07154|https://www.uniprot.org/uniprot/P06797|https://www.uniprot.org/uniprot/O97431|https://www.uniprot.org/uniprot/O77502|https://www.uniprot.org/uniprot/M3WXJ1
T839 4028-4037 Protein denotes S protein https://www.uniprot.org/uniprot/Q9UIP0|https://www.uniprot.org/uniprot/Q9UIN9|https://www.uniprot.org/uniprot/Q9UIN8|https://www.uniprot.org/uniprot/Q9UIN7|https://www.uniprot.org/uniprot/Q9UIN6|https://www.uniprot.org/uniprot/Q9UBH8|https://www.uniprot.org/uniprot/Q9NRH8|https://www.uniprot.org/uniprot/Q9NRH7|https://www.uniprot.org/uniprot/Q9NRH6|https://www.uniprot.org/uniprot/Q9NRH5|https://www.uniprot.org/uniprot/Q9NRH4|https://www.uniprot.org/uniprot/Q9NPG5|https://www.uniprot.org/uniprot/Q9NPE0|https://www.uniprot.org/uniprot/Q9NP52|https://www.uniprot.org/uniprot/Q95IF9|https://www.uniprot.org/uniprot/Q8N5P3|https://www.uniprot.org/uniprot/Q8IZU6|https://www.uniprot.org/uniprot/Q8IZU5|https://www.uniprot.org/uniprot/Q8IZU4|https://www.uniprot.org/uniprot/Q86Z04|https://www.uniprot.org/uniprot/Q7YR44|https://www.uniprot.org/uniprot/Q7LA71|https://www.uniprot.org/uniprot/Q7LA70|https://www.uniprot.org/uniprot/Q5STD2|https://www.uniprot.org/uniprot/Q5SQ85|https://www.uniprot.org/uniprot/Q1XI16|https://www.uniprot.org/uniprot/Q1XI12|https://www.uniprot.org/uniprot/Q15517|https://www.uniprot.org/uniprot/O43509|https://www.uniprot.org/uniprot/O19084|https://www.uniprot.org/uniprot/B0UYZ7|https://www.uniprot.org/uniprot/B0S7V2|https://www.uniprot.org/uniprot/A5A6L9
T872 4953-4962 Protein denotes embryonic https://www.uniprot.org/uniprot/P02301
T873 5030-5038 Protein denotes p38 MAPK https://www.uniprot.org/uniprot/Q9TXB4|https://www.uniprot.org/uniprot/O62618|https://www.uniprot.org/uniprot/O46216|https://www.uniprot.org/uniprot/A4V3C0
T877 5308-5312 Protein denotes MAVS https://www.uniprot.org/uniprot/Q9ULE9|https://www.uniprot.org/uniprot/Q9H8D3|https://www.uniprot.org/uniprot/Q9H4Y1|https://www.uniprot.org/uniprot/Q9H1H3|https://www.uniprot.org/uniprot/Q8VCF0|https://www.uniprot.org/uniprot/Q86VY7|https://www.uniprot.org/uniprot/Q7Z434|https://www.uniprot.org/uniprot/Q66HG9|https://www.uniprot.org/uniprot/Q5T7I6|https://www.uniprot.org/uniprot/Q3I0Y2|https://www.uniprot.org/uniprot/Q2HWT5|https://www.uniprot.org/uniprot/M1P2Z0|https://www.uniprot.org/uniprot/F5H6C8|https://www.uniprot.org/uniprot/B2BD34|https://www.uniprot.org/uniprot/B2BD33|https://www.uniprot.org/uniprot/A8K6X0
T893 5460-5468 Protein denotes p38 MAPK https://www.uniprot.org/uniprot/Q9TXB4|https://www.uniprot.org/uniprot/O62618|https://www.uniprot.org/uniprot/O46216|https://www.uniprot.org/uniprot/A4V3C0
T897 5956-5961 Protein denotes CD154 https://www.uniprot.org/uniprot/Q9Z2V2|https://www.uniprot.org/uniprot/Q9R254|https://www.uniprot.org/uniprot/Q9BDN3|https://www.uniprot.org/uniprot/Q9BDM7|https://www.uniprot.org/uniprot/Q9BDM3|https://www.uniprot.org/uniprot/Q9BDC7|https://www.uniprot.org/uniprot/Q95MQ5|https://www.uniprot.org/uniprot/P63305|https://www.uniprot.org/uniprot/P63304|https://www.uniprot.org/uniprot/P51749|https://www.uniprot.org/uniprot/P29965|https://www.uniprot.org/uniprot/P27548|https://www.uniprot.org/uniprot/O97626|https://www.uniprot.org/uniprot/O97605
T911 5980-5983 Protein denotes CD4 https://www.uniprot.org/uniprot/Q9XS78|https://www.uniprot.org/uniprot/Q9UDE5|https://www.uniprot.org/uniprot/Q5U066|https://www.uniprot.org/uniprot/Q4ZGK2|https://www.uniprot.org/uniprot/Q29617|https://www.uniprot.org/uniprot/Q29037|https://www.uniprot.org/uniprot/Q28217|https://www.uniprot.org/uniprot/Q08340|https://www.uniprot.org/uniprot/Q08339|https://www.uniprot.org/uniprot/Q08338|https://www.uniprot.org/uniprot/Q08336|https://www.uniprot.org/uniprot/P79196|https://www.uniprot.org/uniprot/P79185|https://www.uniprot.org/uniprot/P79184|https://www.uniprot.org/uniprot/P46630|https://www.uniprot.org/uniprot/P33705|https://www.uniprot.org/uniprot/P16004|https://www.uniprot.org/uniprot/P16003|https://www.uniprot.org/uniprot/P06332|https://www.uniprot.org/uniprot/P05542|https://www.uniprot.org/uniprot/P05540|https://www.uniprot.org/uniprot/P01730|https://www.uniprot.org/uniprot/O77593|https://www.uniprot.org/uniprot/O02805|https://www.uniprot.org/uniprot/D3DUS5|https://www.uniprot.org/uniprot/B2R737
T937 6054-6058 Protein denotes IL-6 https://www.uniprot.org/uniprot/Q9XT80|https://www.uniprot.org/uniprot/Q9UCU4|https://www.uniprot.org/uniprot/Q9UCU3|https://www.uniprot.org/uniprot/Q9UCU2|https://www.uniprot.org/uniprot/Q9MZR1|https://www.uniprot.org/uniprot/Q9MYZ7|https://www.uniprot.org/uniprot/Q95KN6|https://www.uniprot.org/uniprot/Q95181|https://www.uniprot.org/uniprot/Q90YI0|https://www.uniprot.org/uniprot/Q8MKH0|https://www.uniprot.org/uniprot/Q8BN26|https://www.uniprot.org/uniprot/Q865X6|https://www.uniprot.org/uniprot/Q865W7|https://www.uniprot.org/uniprot/Q6V919|https://www.uniprot.org/uniprot/Q6L6X6|https://www.uniprot.org/uniprot/Q5I6E3|https://www.uniprot.org/uniprot/Q3UCQ0|https://www.uniprot.org/uniprot/Q2MH06|https://www.uniprot.org/uniprot/Q28819|https://www.uniprot.org/uniprot/Q28747|https://www.uniprot.org/uniprot/Q28319|https://www.uniprot.org/uniprot/Q25BC2|https://www.uniprot.org/uniprot/Q0PW36|https://www.uniprot.org/uniprot/Q0GGL7|https://www.uniprot.org/uniprot/Q08DT2|https://www.uniprot.org/uniprot/P79341|https://www.uniprot.org/uniprot/P51494|https://www.uniprot.org/uniprot/P46650|https://www.uniprot.org/uniprot/P41693|https://www.uniprot.org/uniprot/P41683|https://www.uniprot.org/uniprot/P41323|https://www.uniprot.org/uniprot/P29455|https://www.uniprot.org/uniprot/P26893|https://www.uniprot.org/uniprot/P26892|https://www.uniprot.org/uniprot/P20607|https://www.uniprot.org/uniprot/P08505|https://www.uniprot.org/uniprot/P05231|https://www.uniprot.org/uniprot/O46568|https://www.uniprot.org/uniprot/O35736|https://www.uniprot.org/uniprot/O19007|https://www.uniprot.org/uniprot/B6CKP4|https://www.uniprot.org/uniprot/A9QWQ9|https://www.uniprot.org/uniprot/A3FBE9|https://www.uniprot.org/uniprot/A0S0B0
T981 6063-6084 Protein denotes tumor necrosis factor https://www.uniprot.org/uniprot/Q9UIV3|https://www.uniprot.org/uniprot/Q9TTJ3|https://www.uniprot.org/uniprot/Q9P1Q2|https://www.uniprot.org/uniprot/Q9MYZ2|https://www.uniprot.org/uniprot/Q9JI27|https://www.uniprot.org/uniprot/Q9JI26|https://www.uniprot.org/uniprot/Q9BEA1|https://www.uniprot.org/uniprot/Q91VF3|https://www.uniprot.org/uniprot/Q8WNR1|https://www.uniprot.org/uniprot/Q8MKG8|https://www.uniprot.org/uniprot/Q8JFG3|https://www.uniprot.org/uniprot/Q8HZD9|https://www.uniprot.org/uniprot/Q8HZD6|https://www.uniprot.org/uniprot/Q8HYM0|https://www.uniprot.org/uniprot/Q75N23|https://www.uniprot.org/uniprot/Q6EE11|https://www.uniprot.org/uniprot/Q62326|https://www.uniprot.org/uniprot/Q5TM21|https://www.uniprot.org/uniprot/Q539C2|https://www.uniprot.org/uniprot/Q2MH05|https://www.uniprot.org/uniprot/P29553|https://www.uniprot.org/uniprot/P23563|https://www.uniprot.org/uniprot/P23383|https://www.uniprot.org/uniprot/P19101|https://www.uniprot.org/uniprot/P16599|https://www.uniprot.org/uniprot/P13296|https://www.uniprot.org/uniprot/P06804|https://www.uniprot.org/uniprot/P04924|https://www.uniprot.org/uniprot/P01375|https://www.uniprot.org/uniprot/O77764|https://www.uniprot.org/uniprot/O77510|https://www.uniprot.org/uniprot/O43647|https://www.uniprot.org/uniprot/O35853|https://www.uniprot.org/uniprot/O35734|https://www.uniprot.org/uniprot/O18779|https://www.uniprot.org/uniprot/A9QWR7|https://www.uniprot.org/uniprot/A5D9N8|https://www.uniprot.org/uniprot/A4IFT5|https://www.uniprot.org/uniprot/Q28339|https://www.uniprot.org/uniprot/Q28320|https://www.uniprot.org/uniprot/Q27978|https://www.uniprot.org/uniprot/Q1XHZ6|https://www.uniprot.org/uniprot/Q1WM27|https://www.uniprot.org/uniprot/Q1G1A2|https://www.uniprot.org/uniprot/Q19LH4|https://www.uniprot.org/uniprot/Q06599|https://www.uniprot.org/uniprot/Q006K5|https://www.uniprot.org/uniprot/P79374|https://www.uniprot.org/uniprot/P79337|https://www.uniprot.org/uniprot/P59695|https://www.uniprot.org/uniprot/P59694|https://www.uniprot.org/uniprot/P59693|https://www.uniprot.org/uniprot/P59684|https://www.uniprot.org/uniprot/P51743|https://www.uniprot.org/uniprot/P51742|https://www.uniprot.org/uniprot/P51435|https://www.uniprot.org/uniprot/P48094|https://www.uniprot.org/uniprot/P36939|https://www.uniprot.org/uniprot/P33620
T1040 6362-6378 Protein denotes (cGAMP) synthase https://www.uniprot.org/uniprot/Q96E45|https://www.uniprot.org/uniprot/Q8N884|https://www.uniprot.org/uniprot/Q8C6L5|https://www.uniprot.org/uniprot/Q5SWL1|https://www.uniprot.org/uniprot/Q5SWL0|https://www.uniprot.org/uniprot/Q3ULW3|https://www.uniprot.org/uniprot/Q32NC9|https://www.uniprot.org/uniprot/Q14CV6|https://www.uniprot.org/uniprot/L0L2J9|https://www.uniprot.org/uniprot/I3LM39|https://www.uniprot.org/uniprot/E1BGN7|https://www.uniprot.org/uniprot/A7SFB5
T1052 6380-6384 Protein denotes cGAS https://www.uniprot.org/uniprot/Q96E45|https://www.uniprot.org/uniprot/Q8N884|https://www.uniprot.org/uniprot/Q8C6L5|https://www.uniprot.org/uniprot/Q5SWL1|https://www.uniprot.org/uniprot/Q5SWL0|https://www.uniprot.org/uniprot/Q3ULW3|https://www.uniprot.org/uniprot/Q32NC9|https://www.uniprot.org/uniprot/Q14CV6|https://www.uniprot.org/uniprot/L0L2J9|https://www.uniprot.org/uniprot/I3LM39|https://www.uniprot.org/uniprot/E1BGN7|https://www.uniprot.org/uniprot/A7SFB5
T1064 6448-6458 Protein denotes interferon https://www.uniprot.org/uniprot/P51527|https://www.uniprot.org/uniprot/P51526
T1066 6510-6526 Protein denotes phospholipase A2 https://www.uniprot.org/uniprot/Q05017|https://www.uniprot.org/uniprot/P86780|https://www.uniprot.org/uniprot/P86517|https://www.uniprot.org/uniprot/P86043|https://www.uniprot.org/uniprot/P82971|https://www.uniprot.org/uniprot/P59066|https://www.uniprot.org/uniprot/P50393|https://www.uniprot.org/uniprot/P50392|https://www.uniprot.org/uniprot/P49147|https://www.uniprot.org/uniprot/P47713|https://www.uniprot.org/uniprot/P47712|https://www.uniprot.org/uniprot/P43434|https://www.uniprot.org/uniprot/P18999|https://www.uniprot.org/uniprot/P14419|https://www.uniprot.org/uniprot/P0DPT8|https://www.uniprot.org/uniprot/P0DP54|https://www.uniprot.org/uniprot/P0CV89|https://www.uniprot.org/uniprot/P0C8L9|https://www.uniprot.org/uniprot/P06596|https://www.uniprot.org/uniprot/P04362|https://www.uniprot.org/uniprot/P04055|https://www.uniprot.org/uniprot/P04054|https://www.uniprot.org/uniprot/P00630|https://www.uniprot.org/uniprot/P00594|https://www.uniprot.org/uniprot/P00593|https://www.uniprot.org/uniprot/O77793|https://www.uniprot.org/uniprot/O70320|https://www.uniprot.org/uniprot/O54728|https://www.uniprot.org/uniprot/F5CPF0|https://www.uniprot.org/uniprot/C0HLL2|https://www.uniprot.org/uniprot/C0HLB8|https://www.uniprot.org/uniprot/B3EWQ8|https://www.uniprot.org/uniprot/B3EWP6|https://www.uniprot.org/uniprot/B2R4H5|https://www.uniprot.org/uniprot/B1WAZ6|https://www.uniprot.org/uniprot/B1AKG4|https://www.uniprot.org/uniprot/A8KAX2|https://www.uniprot.org/uniprot/A6H6K5|https://www.uniprot.org/uniprot/A5JGM7|https://www.uniprot.org/uniprot/A4IFJ5|https://www.uniprot.org/uniprot/A0A5C2A2T2|https://www.uniprot.org/uniprot/A0A5C1ZXT8|https://www.uniprot.org/uniprot/A0A5C1ZW08|https://www.uniprot.org/uniprot/Q9Z0Y2|https://www.uniprot.org/uniprot/Q9TWL9|https://www.uniprot.org/uniprot/Q9TT38|https://www.uniprot.org/uniprot/Q9PRZ0|https://www.uniprot.org/uniprot/Q9D884|https://www.uniprot.org/uniprot/Q9D7E2|https://www.uniprot.org/uniprot/Q9D4Y6|https://www.uniprot.org/uniprot/Q9BMK4|https://www.uniprot.org/uniprot/Q96DP9|https://www.uniprot.org/uniprot/Q8WPH5|https://www.uniprot.org/uniprot/Q8IUP7|https://www.uniprot.org/uniprot/Q7T0T9|https://www.uniprot.org/uniprot/Q7M4I6|https://www.uniprot.org/uniprot/Q7M4I5|https://www.uniprot.org/uniprot/Q7M3V3|https://www.uniprot.org/uniprot/Q7M334|https://www.uniprot.org/uniprot/Q7LZG3|https://www.uniprot.org/uniprot/Q6T178|https://www.uniprot.org/uniprot/Q6P1J6|https://www.uniprot.org/uniprot/Q5R8A5|https://www.uniprot.org/uniprot/Q53S03|https://www.uniprot.org/uniprot/Q3TTY0|https://www.uniprot.org/uniprot/Q3KPI1|https://www.uniprot.org/uniprot/Q29R80|https://www.uniprot.org/uniprot/Q1XD55|https://www.uniprot.org/uniprot/Q0VEX7|https://www.uniprot.org/uniprot/Q06HQ7
T1136 6733-6737 Protein denotes IL-6 https://www.uniprot.org/uniprot/Q9XT80|https://www.uniprot.org/uniprot/Q9UCU4|https://www.uniprot.org/uniprot/Q9UCU3|https://www.uniprot.org/uniprot/Q9UCU2|https://www.uniprot.org/uniprot/Q9MZR1|https://www.uniprot.org/uniprot/Q9MYZ7|https://www.uniprot.org/uniprot/Q95KN6|https://www.uniprot.org/uniprot/Q95181|https://www.uniprot.org/uniprot/Q90YI0|https://www.uniprot.org/uniprot/Q8MKH0|https://www.uniprot.org/uniprot/Q8BN26|https://www.uniprot.org/uniprot/Q865X6|https://www.uniprot.org/uniprot/Q865W7|https://www.uniprot.org/uniprot/Q6V919|https://www.uniprot.org/uniprot/Q6L6X6|https://www.uniprot.org/uniprot/Q5I6E3|https://www.uniprot.org/uniprot/Q3UCQ0|https://www.uniprot.org/uniprot/Q2MH06|https://www.uniprot.org/uniprot/Q28819|https://www.uniprot.org/uniprot/Q28747|https://www.uniprot.org/uniprot/Q28319|https://www.uniprot.org/uniprot/Q25BC2|https://www.uniprot.org/uniprot/Q0PW36|https://www.uniprot.org/uniprot/Q0GGL7|https://www.uniprot.org/uniprot/Q08DT2|https://www.uniprot.org/uniprot/P79341|https://www.uniprot.org/uniprot/P51494|https://www.uniprot.org/uniprot/P46650|https://www.uniprot.org/uniprot/P41693|https://www.uniprot.org/uniprot/P41683|https://www.uniprot.org/uniprot/P41323|https://www.uniprot.org/uniprot/P29455|https://www.uniprot.org/uniprot/P26893|https://www.uniprot.org/uniprot/P26892|https://www.uniprot.org/uniprot/P20607|https://www.uniprot.org/uniprot/P08505|https://www.uniprot.org/uniprot/P05231|https://www.uniprot.org/uniprot/O46568|https://www.uniprot.org/uniprot/O35736|https://www.uniprot.org/uniprot/O19007|https://www.uniprot.org/uniprot/B6CKP4|https://www.uniprot.org/uniprot/A9QWQ9|https://www.uniprot.org/uniprot/A3FBE9|https://www.uniprot.org/uniprot/A0S0B0
T1180 6742-6747 Protein denotes IL-10 https://www.uniprot.org/uniprot/Q9Z1Y5|https://www.uniprot.org/uniprot/Q9TSJ7|https://www.uniprot.org/uniprot/Q9TSJ4|https://www.uniprot.org/uniprot/Q9JHK7|https://www.uniprot.org/uniprot/Q8MKG9|https://www.uniprot.org/uniprot/Q865X4|https://www.uniprot.org/uniprot/Q6A2H5|https://www.uniprot.org/uniprot/Q6A2H4|https://www.uniprot.org/uniprot/Q63263|https://www.uniprot.org/uniprot/Q5Q0V6|https://www.uniprot.org/uniprot/Q2PE73|https://www.uniprot.org/uniprot/Q29408|https://www.uniprot.org/uniprot/Q29055|https://www.uniprot.org/uniprot/Q28374|https://www.uniprot.org/uniprot/Q25BC1|https://www.uniprot.org/uniprot/Q1W5D6|https://www.uniprot.org/uniprot/Q0Z972|https://www.uniprot.org/uniprot/Q0VBJ1|https://www.uniprot.org/uniprot/P79338|https://www.uniprot.org/uniprot/P55029|https://www.uniprot.org/uniprot/P51746|https://www.uniprot.org/uniprot/P51497|https://www.uniprot.org/uniprot/P51496|https://www.uniprot.org/uniprot/P48411|https://www.uniprot.org/uniprot/P47965|https://www.uniprot.org/uniprot/P46651|https://www.uniprot.org/uniprot/P43480|https://www.uniprot.org/uniprot/P29456|https://www.uniprot.org/uniprot/P22301|https://www.uniprot.org/uniprot/P18893|https://www.uniprot.org/uniprot/O97798|https://www.uniprot.org/uniprot/O46673|https://www.uniprot.org/uniprot/A9QWR2|https://www.uniprot.org/uniprot/A2T6Z6

LitCovid-sample-PD-IDO

Id Subject Object Predicate Lexical cue
T57 53-62 http://purl.obolibrary.org/obo/IDO_0000559 denotes Antiviral
T58 165-169 http://purl.obolibrary.org/obo/IDO_0000531 denotes host
T59 243-247 http://purl.obolibrary.org/obo/IDO_0000531 denotes host
T60 248-252 http://purl.obolibrary.org/obo/CL_0000000 denotes cell
T61 313-318 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T62 360-365 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T63 374-378 http://purl.obolibrary.org/obo/IDO_0000531 denotes host
T64 379-383 http://purl.obolibrary.org/obo/CL_0000000 denotes cell
T65 455-460 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T66 671-675 http://purl.obolibrary.org/obo/CL_0000000 denotes cell
T67 769-773 http://purl.obolibrary.org/obo/BFO_0000029 denotes site
T68 1147-1158 http://purl.obolibrary.org/obo/IDO_0000608 denotes replication
T69 1174-1189 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T70 1224-1233 http://purl.obolibrary.org/obo/IDO_0000559 denotes antiviral
T71 1584-1588 http://purl.obolibrary.org/obo/IDO_0000531 denotes host
T72 1700-1704 http://purl.obolibrary.org/obo/CL_0000000 denotes cell
T73 1741-1751 http://purl.obolibrary.org/obo/IDO_0000607 denotes production
T74 1804-1809 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T75 1816-1821 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T76 1884-1891 http://purl.obolibrary.org/obo/OGMS_0000031 denotes disease
T77 2217-2226 http://purl.obolibrary.org/obo/IDO_0000586 denotes infection
T78 2230-2234 http://purl.obolibrary.org/obo/IDO_0000531 denotes host
T79 2235-2240 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T80 2355-2362 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T81 2612-2616 http://purl.obolibrary.org/obo/IDO_0000531 denotes host
T82 2617-2621 http://purl.obolibrary.org/obo/CL_0000000 denotes cell
T83 3136-3143 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T84 3155-3159 http://purl.obolibrary.org/obo/CL_0000000 denotes cell
T85 3859-3864 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T86 3935-3940 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T87 4234-4239 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T88 4613-4618 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T89 4623-4627 http://purl.obolibrary.org/obo/IDO_0000531 denotes host
T90 4678-4682 http://purl.obolibrary.org/obo/CL_0000000 denotes cell
T91 4705-4709 http://purl.obolibrary.org/obo/IDO_0000531 denotes host
T92 4807-4811 http://purl.obolibrary.org/obo/CL_0000000 denotes cell
T93 4851-4860 http://purl.obolibrary.org/obo/IDO_0000586 denotes infection
T94 4932-4943 http://purl.obolibrary.org/obo/IDO_0000608 denotes replication
T95 4979-4984 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T96 5085-5095 http://purl.obolibrary.org/obo/IDO_0000607 denotes production
T97 5238-5242 http://purl.obolibrary.org/obo/IDO_0000531 denotes host
T98 5287-5296 http://purl.obolibrary.org/obo/IDO_0000559 denotes antiviral
T99 5348-5353 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T100 5408-5417 http://purl.obolibrary.org/obo/IDO_0000559 denotes antiviral
T101 5495-5499 http://purl.obolibrary.org/obo/IDO_0000531 denotes host
T102 5560-5564 http://purl.obolibrary.org/obo/CL_0000000 denotes cell
T103 5589-5599 http://purl.obolibrary.org/obo/IDO_0000607 denotes production
T104 5916-5920 http://purl.obolibrary.org/obo/CL_0000000 denotes cell
T105 5988-5993 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T106 6095-6108 http://purl.obolibrary.org/obo/IDO_0000607 denotes produced by T
T107 6109-6114 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T108 6121-6126 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T109 6294-6304 http://purl.obolibrary.org/obo/IDO_0000607 denotes production
T110 6459-6469 http://purl.obolibrary.org/obo/IDO_0000607 denotes production
T111 6590-6600 http://purl.obolibrary.org/obo/IDO_0000607 denotes production
T112 6802-6810 http://purl.obolibrary.org/obo/IDO_0000586 denotes infected
T113 6903-6910 http://purl.obolibrary.org/obo/OGMS_0000031 denotes disease
T114 6938-6953 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response

LitCovid-sample-PD-FMA

Id Subject Object Predicate Lexical cue fma_id
T26 129-136 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T27 248-260 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T28 248-252 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T29 379-392 Body_part denotes cell membrane http://purl.org/sig/ont/fma/fma63841
T30 379-383 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T31 455-460 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T32 586-593 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T33 671-683 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T34 671-675 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T35 1003-1010 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T36 1398-1405 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T37 1444-1455 Body_part denotes ganglioside http://purl.org/sig/ont/fma/fma82816
T38 1623-1626 Body_part denotes MHC http://purl.org/sig/ont/fma/fma84079
T39 1700-1704 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T40 1755-1764 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T41 1804-1809 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T42 1816-1821 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T43 1985-1992 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T44 2001-2004 Body_part denotes MHC http://purl.org/sig/ont/fma/fma84079
T45 2009-2041 Body_part denotes major histocompatibility complex http://purl.org/sig/ont/fma/fma84079
T46 2125-2127 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T47 2129-2140 Body_part denotes interleukin http://purl.org/sig/ont/fma/fma86578
T48 2189-2196 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T49 2197-2215 Body_part denotes membrane receptors http://purl.org/sig/ont/fma/fma0326969
T50 2235-2240 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T51 2288-2301 Body_part denotes glycoproteins http://purl.org/sig/ont/fma/fma62925
T52 2306-2318 Body_part denotes gangliosides http://purl.org/sig/ont/fma/fma82816
T53 2592-2604 Body_part denotes gangliosides http://purl.org/sig/ont/fma/fma82816
T54 2617-2629 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T55 2617-2621 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T56 2689-2701 Body_part denotes gangliosides http://purl.org/sig/ont/fma/fma82816
T57 2770-2777 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T58 2781-2793 Body_part denotes gangliosides http://purl.org/sig/ont/fma/fma82816
T59 3036-3047 Body_part denotes ganglioside http://purl.org/sig/ont/fma/fma82816
T60 3132-3135 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T61 3155-3159 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T62 3276-3285 Body_part denotes endosomal http://purl.org/sig/ont/fma/fma67180
T63 3286-3297 Body_part denotes compartment http://purl.org/sig/ont/fma/fma76577
T64 3529-3535 Body_part denotes serine http://purl.org/sig/ont/fma/fma82764
T65 3587-3594 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T66 3770-3778 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T67 3935-3940 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T68 4030-4037 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T69 4179-4194 Body_part denotes early endosomes http://purl.org/sig/ont/fma/fma67463
T70 4234-4239 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T71 4367-4376 Body_part denotes endosomal http://purl.org/sig/ont/fma/fma67180
T72 4501-4509 Body_part denotes endosome http://purl.org/sig/ont/fma/fma67180
T73 4556-4565 Body_part denotes lysosomal http://purl.org/sig/ont/fma/fma63836
T74 4678-4682 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T75 4750-4757 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T76 4807-4819 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T77 4807-4811 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T78 4963-4967 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T79 4968-4984 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T80 4979-4984 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T81 5560-5564 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T82 5580-5588 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T83 5751-5760 Body_part denotes lysosomal http://purl.org/sig/ont/fma/fma63836
T84 5802-5834 Body_part denotes major histocompatibility complex http://purl.org/sig/ont/fma/fma84079
T85 5836-5839 Body_part denotes MHC http://purl.org/sig/ont/fma/fma84079
T86 5916-5920 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T87 5988-5993 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T88 6016-6025 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T89 6034-6045 Body_part denotes interleukin http://purl.org/sig/ont/fma/fma86578
T90 6046-6052 Body_part denotes (IL)-1 http://purl.org/sig/ont/fma/fma86583
T91 6047-6049 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T92 6054-6056 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T93 6109-6114 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T94 6121-6126 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T95 6162-6171 Body_part denotes endosomal http://purl.org/sig/ont/fma/fma67180
T96 6308-6317 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T97 6409-6418 Body_part denotes cytosolic http://purl.org/sig/ont/fma/fma66836
T98 6419-6422 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T99 6686-6695 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T100 6733-6735 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T101 6742-6744 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T102 6768-6774 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T103 6852-6860 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050

LitCovid-sample-PD-MAT

Id Subject Object Predicate Lexical cue
T3 4963-4967 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung

LitCovid-sample-PD-GO-BP-0

Id Subject Object Predicate Lexical cue
T3 553-562 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T4 567-580 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T5 725-738 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T6 746-768 http://purl.obolibrary.org/obo/GO_0033578 denotes terminal glycosylation
T7 755-768 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T8 896-918 http://purl.obolibrary.org/obo/GO_0033578 denotes terminal glycosylation
T9 905-918 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T10 1174-1189 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T11 1472-1487 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion
T12 1524-1537 http://purl.obolibrary.org/obo/GO_0045851 denotes acidification
T13 1555-1558 http://purl.obolibrary.org/obo/GO_0004707 denotes p38
T14 1623-1626 http://purl.obolibrary.org/obo/GO_0046776 denotes MHC
T15 1714-1723 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T16 1961-1965 http://purl.obolibrary.org/obo/GO_0004707 denotes MAPK
T17 2001-2004 http://purl.obolibrary.org/obo/GO_0046776 denotes MHC
T18 2009-2041 http://purl.obolibrary.org/obo/GO_0046776 denotes major histocompatibility complex
T19 2155-2163 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T20 2155-2163 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T21 2155-2163 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T22 2155-2163 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T23 2870-2882 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis
T24 3089-3104 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion
T25 3205-3234 http://purl.obolibrary.org/obo/GO_0006898 denotes receptor-mediated endocytosis
T26 3223-3234 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T27 3241-3256 http://purl.obolibrary.org/obo/GO_0061025 denotes Membrane fusion
T28 3304-3315 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T29 3360-3373 http://purl.obolibrary.org/obo/GO_0045851 denotes acidification
T30 3624-3639 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion
T31 3956-3967 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T32 4147-4159 http://purl.obolibrary.org/obo/GO_0051179 denotes localization
T33 4289-4298 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T34 4510-4523 http://purl.obolibrary.org/obo/GO_0045851 denotes acidification
T35 4683-4700 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T36 4683-4692 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T37 4766-4770 http://purl.obolibrary.org/obo/GO_0004707 denotes MAPK
T38 5030-5033 http://purl.obolibrary.org/obo/GO_0004707 denotes p38
T39 5034-5038 http://purl.obolibrary.org/obo/GO_0004707 denotes MAPK
T40 5189-5204 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immunity
T41 5297-5306 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T42 5460-5463 http://purl.obolibrary.org/obo/GO_0004707 denotes p38
T43 5464-5468 http://purl.obolibrary.org/obo/GO_0004707 denotes MAPK
T44 5558-5575 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T45 5560-5575 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T46 5580-5599 http://purl.obolibrary.org/obo/GO_0001816 denotes cytokine production
T47 5703-5731 http://purl.obolibrary.org/obo/GO_0051454 denotes Intracellular alkalinization
T48 5782-5800 http://purl.obolibrary.org/obo/GO_0019882 denotes antigen processing
T49 5802-5834 http://purl.obolibrary.org/obo/GO_0046776 denotes major histocompatibility complex
T50 5836-5839 http://purl.obolibrary.org/obo/GO_0046776 denotes MHC
T51 5906-5931 http://purl.obolibrary.org/obo/GO_0050868 denotes inhibit T cell activation
T52 5914-5931 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T53 5916-5931 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T54 6069-6077 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T55 6069-6077 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T56 6069-6077 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T57 6069-6077 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T58 6219-6228 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T59 6441-6469 http://purl.obolibrary.org/obo/GO_0032606 denotes type I interferon production
T60 6448-6469 http://purl.obolibrary.org/obo/GO_0001816 denotes interferon production
T61 6510-6523 http://purl.obolibrary.org/obo/GO_0004623 denotes phospholipase
T62 6541-6551 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T63 6938-6953 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response

LitCovid-sample-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T56 37-45 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T57 140-150 Disease denotes SARS-CoV-2 http://purl.obolibrary.org/obo/MONDO_0100096
T58 488-498 Disease denotes SARS-CoV-2 http://purl.obolibrary.org/obo/MONDO_0100096
T59 612-620 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T60 992-996 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T61 1266-1274 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T62 1862-1870 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T63 1872-1896 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T64 2149-2154 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T65 2217-2226 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T66 2385-2394 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T67 2420-2428 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T68 2510-2520 Disease denotes SARS-CoV-2 http://purl.obolibrary.org/obo/MONDO_0100096
T69 3793-3801 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T70 3849-3858 Disease denotes hepatitis http://purl.obolibrary.org/obo/MONDO_0002251
T71 3907-3917 Disease denotes SARS-CoV-2 http://purl.obolibrary.org/obo/MONDO_0100096
T72 4017-4027 Disease denotes SARS-CoV-2 http://purl.obolibrary.org/obo/MONDO_0100096
T73 4122-4132 Disease denotes SARS-CoV-2 http://purl.obolibrary.org/obo/MONDO_0100096
T74 4163-4173 Disease denotes SARS-CoV-2 http://purl.obolibrary.org/obo/MONDO_0100096
T75 4302-4312 Disease denotes SARS-CoV-2 http://purl.obolibrary.org/obo/MONDO_0100096
T76 4851-4860 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T77 4890-4898 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T78 5341-5347 Disease denotes dengue http://purl.obolibrary.org/obo/MONDO_0005502
T79 6063-6068 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T80 6816-6826 Disease denotes SARS-CoV-2 http://purl.obolibrary.org/obo/MONDO_0100096
T81 6879-6882 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T83 6994-6997 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T85 7027-7035 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-sample-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T8 2149-2154 Phenotype denotes tumor http://purl.obolibrary.org/obo/HP_0002664
T9 3849-3858 Phenotype denotes hepatitis http://purl.obolibrary.org/obo/HP_0012115
T10 6063-6068 Phenotype denotes tumor http://purl.obolibrary.org/obo/HP_0002664

LitCovid-sample-GO-BP

Id Subject Object Predicate Lexical cue
T3 553-562 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T4 567-580 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T5 725-738 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T6 746-768 http://purl.obolibrary.org/obo/GO_0033578 denotes terminal glycosylation
T7 755-768 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T8 896-918 http://purl.obolibrary.org/obo/GO_0033578 denotes terminal glycosylation
T9 905-918 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T10 1174-1189 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T11 1472-1487 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion
T12 1524-1537 http://purl.obolibrary.org/obo/GO_0045851 denotes acidification
T13 1623-1626 http://purl.obolibrary.org/obo/GO_0046776 denotes MHC
T14 1714-1723 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T15 1961-1965 http://purl.obolibrary.org/obo/GO_0004707 denotes MAPK
T16 2001-2004 http://purl.obolibrary.org/obo/GO_0046776 denotes MHC
T17 2009-2041 http://purl.obolibrary.org/obo/GO_0046776 denotes major histocompatibility complex
T18 2155-2163 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T19 2155-2163 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T20 2155-2163 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T21 2155-2163 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T22 2870-2882 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis
T23 3089-3104 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion
T24 3205-3234 http://purl.obolibrary.org/obo/GO_0006898 denotes receptor-mediated endocytosis
T25 3223-3234 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T26 3241-3256 http://purl.obolibrary.org/obo/GO_0061025 denotes Membrane fusion
T27 3304-3315 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T28 3360-3373 http://purl.obolibrary.org/obo/GO_0045851 denotes acidification
T29 3624-3639 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion
T30 3956-3967 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T31 4147-4159 http://purl.obolibrary.org/obo/GO_0051179 denotes localization
T32 4289-4298 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T33 4510-4523 http://purl.obolibrary.org/obo/GO_0045851 denotes acidification
T34 4683-4700 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T35 4683-4692 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T36 4766-4770 http://purl.obolibrary.org/obo/GO_0004707 denotes MAPK
T37 5034-5038 http://purl.obolibrary.org/obo/GO_0004707 denotes MAPK
T38 5189-5204 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immunity
T39 5297-5306 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T40 5464-5468 http://purl.obolibrary.org/obo/GO_0004707 denotes MAPK
T41 5558-5575 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T42 5560-5575 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T43 5580-5599 http://purl.obolibrary.org/obo/GO_0001816 denotes cytokine production
T44 5703-5731 http://purl.obolibrary.org/obo/GO_0051454 denotes Intracellular alkalinization
T45 5782-5800 http://purl.obolibrary.org/obo/GO_0019882 denotes antigen processing
T46 5802-5834 http://purl.obolibrary.org/obo/GO_0046776 denotes major histocompatibility complex
T47 5836-5839 http://purl.obolibrary.org/obo/GO_0046776 denotes MHC
T48 5906-5931 http://purl.obolibrary.org/obo/GO_0050868 denotes inhibit T cell activation
T49 5914-5931 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T50 5916-5931 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T51 6069-6077 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T52 6069-6077 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T53 6069-6077 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T54 6069-6077 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T55 6219-6228 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T56 6441-6469 http://purl.obolibrary.org/obo/GO_0032606 denotes type I interferon production
T57 6448-6469 http://purl.obolibrary.org/obo/GO_0001816 denotes interferon production
T58 6541-6551 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T59 6938-6953 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T3 553-562 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T4 567-580 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T5 725-738 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T6 746-768 http://purl.obolibrary.org/obo/GO_0033578 denotes terminal glycosylation
T7 755-768 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T8 896-918 http://purl.obolibrary.org/obo/GO_0033578 denotes terminal glycosylation
T9 905-918 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T10 1174-1189 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T11 1472-1487 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion
T12 1524-1537 http://purl.obolibrary.org/obo/GO_0045851 denotes acidification
T13 1623-1626 http://purl.obolibrary.org/obo/GO_0046776 denotes MHC
T14 1714-1723 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T15 1961-1965 http://purl.obolibrary.org/obo/GO_0004707 denotes MAPK
T16 2001-2004 http://purl.obolibrary.org/obo/GO_0046776 denotes MHC
T17 2009-2041 http://purl.obolibrary.org/obo/GO_0046776 denotes major histocompatibility complex
T18 2155-2163 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T19 2155-2163 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T20 2155-2163 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T21 2155-2163 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T22 2870-2882 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis
T23 3089-3104 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion
T24 3205-3234 http://purl.obolibrary.org/obo/GO_0006898 denotes receptor-mediated endocytosis
T25 3223-3234 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T26 3241-3256 http://purl.obolibrary.org/obo/GO_0061025 denotes Membrane fusion
T27 3304-3315 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T28 3360-3373 http://purl.obolibrary.org/obo/GO_0045851 denotes acidification
T29 3624-3639 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion
T30 3956-3967 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T31 4147-4159 http://purl.obolibrary.org/obo/GO_0051179 denotes localization
T32 4289-4298 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T33 4510-4523 http://purl.obolibrary.org/obo/GO_0045851 denotes acidification
T34 4683-4700 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T35 4683-4692 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T36 4766-4770 http://purl.obolibrary.org/obo/GO_0004707 denotes MAPK
T37 5034-5038 http://purl.obolibrary.org/obo/GO_0004707 denotes MAPK
T38 5189-5204 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immunity
T39 5297-5306 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T40 5464-5468 http://purl.obolibrary.org/obo/GO_0004707 denotes MAPK
T41 5558-5575 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T42 5560-5575 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T43 5580-5599 http://purl.obolibrary.org/obo/GO_0001816 denotes cytokine production
T44 5703-5731 http://purl.obolibrary.org/obo/GO_0051454 denotes Intracellular alkalinization
T45 5782-5800 http://purl.obolibrary.org/obo/GO_0019882 denotes antigen processing
T46 5802-5834 http://purl.obolibrary.org/obo/GO_0046776 denotes major histocompatibility complex
T47 5836-5839 http://purl.obolibrary.org/obo/GO_0046776 denotes MHC
T48 5906-5931 http://purl.obolibrary.org/obo/GO_0050868 denotes inhibit T cell activation
T49 5914-5931 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T50 5916-5931 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T51 6069-6077 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T52 6069-6077 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T53 6069-6077 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T54 6069-6077 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T55 6219-6228 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T56 6441-6469 http://purl.obolibrary.org/obo/GO_0032606 denotes type I interferon production
T57 6448-6469 http://purl.obolibrary.org/obo/GO_0001816 denotes interferon production
T58 6541-6551 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T59 6938-6953 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
313 37-45 Disease denotes COVID-19 MESH:C000657245
322 1387-1391 Gene denotes ACE2 Gene:59272
323 1555-1558 Gene denotes p38 Gene:1432
324 1668-1673 Gene denotes CD154 Gene:959
325 1692-1695 Gene denotes CD4 Gene:920
326 1142-1146 Species denotes CoVs Tax:11118
327 1127-1129 Chemical denotes CQ MESH:D002738
328 1130-1133 Chemical denotes HCQ MESH:D006886
329 1266-1274 Disease denotes COVID-19 MESH:C000657245
350 270-301 Gene denotes angiotensin-converting enzyme 2 Gene:59272
351 303-307 Gene denotes ACE2 Gene:59272
352 440-444 Gene denotes ACE2 Gene:103231639
353 698-702 Gene denotes ACE2 Gene:59272
354 777-781 Gene denotes ACE2 Gene:59272
355 922-926 Gene denotes ACE2 Gene:59272
356 983-987 Gene denotes ACE2 Gene:59272
357 584-585 Gene denotes S Gene:43740568
358 127-128 Gene denotes S Gene:43740568
359 140-150 Species denotes SARS-CoV-2 Tax:2697049
360 612-620 Species denotes SARS-CoV Tax:694009
361 992-1000 Species denotes SARS CoV Tax:694009
362 488-498 Species denotes SARS-CoV-2 Tax:2697049
363 821-824 Species denotes CoV Tax:11118
364 434-436 Chemical denotes CQ MESH:D002738
365 517-519 Chemical denotes CQ MESH:D002738
366 704-706 Chemical denotes CQ MESH:D002738
367 837-839 Chemical denotes CQ MESH:D002738
368 840-843 Chemical denotes HCQ MESH:D006886
369 448-454 CellLine denotes VeroE6 CVCL:0574
394 2535-2539 Gene denotes ACE2 Gene:59272
395 2828-2847 Gene denotes quinone reductase 2 Gene:4835
396 2849-2852 Gene denotes QR2 Gene:4835
397 2659-2665 Gene denotes CQ/HCQ
398 2420-2428 Species denotes SARS-CoV Tax:694009
399 2438-2447 Species denotes HCoV-OC43 Tax:31631
400 2510-2520 Species denotes SARS-CoV-2 Tax:2697049
401 2385-2394 Species denotes influenza Tax:11320
402 2758-2765 Species denotes SARSCoV Tax:694009
403 2937-2940 Species denotes CoV Tax:11118
404 2265-2276 Chemical denotes sialic acid MESH:D019158
405 2306-2318 Chemical denotes gangliosides MESH:D005732
406 2592-2604 Chemical denotes gangliosides MESH:D005732
407 2638-2649 Chemical denotes sialic acid MESH:D019158
408 2672-2684 Chemical denotes sialic acids MESH:D012794
409 2689-2701 Chemical denotes gangliosides MESH:D005732
410 2781-2793 Chemical denotes gangliosides MESH:D005732
411 2800-2802 Chemical denotes CQ MESH:D002738
412 2886-2898 Chemical denotes sialic acids MESH:D012794
413 2953-2955 Chemical denotes CQ MESH:D002738
414 2956-2959 Chemical denotes HCQ MESH:D006886
415 3020-3031 Chemical denotes sialic acid MESH:D019158
416 3036-3047 Chemical denotes ganglioside MESH:D005732
417 2217-2226 Disease denotes infection MESH:D007239
442 3452-3457 Gene denotes furin Gene:5045
443 3658-3669 Gene denotes cathepsin L Gene:1514
444 3978-3989 Gene denotes cathepsin L Gene:1514
445 4346-4352 Gene denotes CQ/HCQ
446 4101-4107 Gene denotes CQ/HCQ
447 4028-4029 Gene denotes S Gene:43740568
448 3113-3117 Species denotes CoVs Tax:11118
452 3843-3864 Species denotes mouse hepatitis virus Tax:11138
453 3907-3917 Species denotes SARS-CoV-2 Tax:2697049
454 4017-4027 Species denotes SARS-CoV-2 Tax:2697049
455 4122-4132 Species denotes SARS-CoV-2 Tax:2697049
456 4163-4173 Species denotes SARS-CoV-2 Tax:2697049
457 4302-4312 Species denotes SARS-CoV-2 Tax:2697049
458 3868-3873 Species denotes MHV-2 Tax:502106
459 4444-4447 Species denotes CoV Tax:11118
460 3529-3535 Chemical denotes serine MESH:D012694
461 4269-4271 Chemical denotes CQ MESH:D002738
462 4460-4462 Chemical denotes CQ MESH:D002738
463 4463-4466 Chemical denotes HCQ MESH:D006886
464 3764-3778 Disease denotes CoV S proteins MESH:C000657245
465 4227-4233 CellLine denotes VeroE6 CVCL:0574
478 5273-5306 Gene denotes mitochondrial antiviral signaling Gene:57506
479 5308-5312 Gene denotes MAVS Gene:57506
480 4864-4868 Species denotes CoVs Tax:11118
481 4890-4898 Species denotes SARS-CoV Tax:694009
482 4922-4931 Species denotes HCoV-229E Tax:11137
483 4947-4952 Species denotes human Tax:9606
484 5055-5058 Chemical denotes HCQ MESH:D006886
485 5108-5131 Chemical denotes reactive oxygen species MESH:D017382
486 5133-5136 Chemical denotes ROS MESH:D017382
487 5211-5214 Chemical denotes HCQ MESH:D006886
488 5380-5386 Chemical denotes CQ/HCQ
489 4851-4860 Disease denotes infection MESH:D007239
520 5956-5961 Gene denotes CD154 Gene:959
521 5980-5983 Gene denotes CD4 Gene:920
522 6034-6052 Gene denotes interleukin (IL)-1 Gene:3552
523 6054-6058 Gene denotes IL-6 Gene:3569
524 6063-6086 Gene denotes tumor necrosis factor-α Gene:7124
525 6088-6093 Gene denotes TNF-α Gene:7124
526 6238-6242 Gene denotes TLR7 Gene:51284
527 6247-6251 Gene denotes TLR9 Gene:54106
528 6347-6378 Gene denotes cyclic GMP-AMP (cGAMP) synthase Gene:115004
529 6380-6384 Gene denotes cGAS Gene:115004
530 6510-6526 Gene denotes phospholipase A2 Gene:5319
531 6733-6737 Gene denotes IL-6 Gene:3569
532 6742-6747 Gene denotes IL-10 Gene:3586
533 6793-6801 Species denotes patients Tax:9606
534 6816-6826 Species denotes SARS-CoV-2 Tax:2697049
535 5735-5737 Chemical denotes CQ MESH:D002738
536 5738-5741 Chemical denotes HCQ MESH:D006886
537 6000-6002 Chemical denotes CQ MESH:D002738
538 6324-6327 Chemical denotes CQ/ MESH:D002738
539 6327-6330 Chemical denotes HCQ MESH:D006886
540 6486-6492 Chemical denotes CQ/HCQ
541 6555-6571 Chemical denotes arachidonic acid MESH:D016718
542 6604-6618 Chemical denotes prostaglandins MESH:D011453
543 6955-6958 Chemical denotes HCQ MESH:D006886
544 6959-6961 Chemical denotes CQ MESH:D002738
545 6778-6792 Disease denotes critically ill MESH:D016638
546 6802-6810 Disease denotes infected MESH:D007239
547 6879-6882 Disease denotes CRS MESH:D003398
548 6994-6997 Disease denotes CRS MESH:D003398
549 7027-7035 Disease denotes COVID-19 MESH:C000657245

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T58 0-2 Sentence denotes 4.
T59 4-45 Sentence denotes Mechanisms of CQ/HCQ in treating COVID-19
T60 47-51 Sentence denotes 4.1.
T61 53-71 Sentence denotes Antiviral activity
T62 73-79 Sentence denotes 4.1.1.
T63 81-122 Sentence denotes Hindrance of receptor recognition process
T64 123-214 Sentence denotes The S protein of SARS-CoV-2 is cleaved by host proteases into two subunits, S1 and S2 [19].
T65 215-398 Sentence denotes The S1 subunit binds to the host cell surface receptor angiotensin-converting enzyme 2 (ACE2) for virus attachment, and the S2 subunit fuses the virus and the host cell membrane [19].
T66 399-787 Sentence denotes The investigation of the effect of CQ on ACE2 in VeroE6 cells showed that effective anti-SARS-CoV-2 concentrations of CQ had no significant effect on the synthesis and glycosylation of S protein on the surface of SARS-CoV, and although it had no significant effect on the cell surface expression of ACE2, CQ could destroy the glycosylation at the terminal glycosylation site of ACE2 [13].
T67 788-1061 Sentence denotes Therefore, the mechanism of anti-CoV activity of CQ/HCQ may be at least partly related to the impairment of terminal glycosylation of ACE2, which may result in reduced binding affinities between ACE2 and SARS CoV S protein, thereby blocking receptor recognition (Figure 1).
T68 1062-1071 Sentence denotes Figure 1.
T69 1072-1190 Sentence denotes Schematic representation of the possible mechanisms of CQ/HCQ against CoVs replication and modulating immune response.
T70 1191-1822 Sentence denotes CQ/HCQ may synergistically exert antiviral and immunomodulatory effects on COVID-19 through multiple mechanisms including hindering the receptor recognition process by influencing the affinity of ACE2 and S protein, and the affinity for sialic acid and ganglioside; inhibiting the membrane fusion process by suppressing endolysosome acidification; suppressing the p38 activation and affecting host defense machinery, and preventing MHC class II expression (block expression of CD154 on the surface of CD4 + T cell) and TLR signaling and reducing the production of cytokines through inhibiting the activation of T cells and B cells.
T71 1823-2173 Sentence denotes ACE2, angiotensin-converting enzyme 2; COVID-19, coronavirus disease 2019; CQ, chloroquine; HCQ, hydroxychloroquine; CoVs, coronaviruses; MAPK, mitogen-activated protein kinase; MHC-II, major histocompatibility complex class II; TLR, toll-like receptor; cGAS, cyclic GMP-AMP synthase; IFN, interferon; IL, interleukin; TNF-α, tumor necrosis factor-α.
T72 2174-2459 Sentence denotes In addition to protein membrane receptors, infection of host cells by HCoVs also relies on sialic acid-containing glycoproteins and gangliosides, which are used by a broad range of viruses as receptors, such as influenza [20] and HCoVs including SARS-CoV [21] and HCoV-OC43 [13,22,23].
T73 2460-2658 Sentence denotes A recent molecular structure analysis showed that SARS-CoV-2 not only uses ACE2 as a receptor, but also recognizes highly conserved gangliosides on the host cell surface through sialic acid [24,25].
T74 2659-2799 Sentence denotes CQ/HCQ binds sialic acids and gangliosides with high affinity, which can prevent the attachment of SARSCoV-2 S protein to gangliosides [25].
T75 2800-2907 Sentence denotes CQ had inhibitory effect on quinone reductase 2 (QR2) involved in the biosynthesis of sialic acids [26,27].
T76 2908-3059 Sentence denotes Hence, the mechanism of anti-CoV activity of CQ/HCQ may also be related to hindering the recognition process of sialic acid and ganglioside (Figure 1).
T77 3061-3067 Sentence denotes 4.1.2.
T78 3069-3112 Sentence denotes Interference of the membrane fusion process
T79 3113-3240 Sentence denotes CoVs are enveloped RNA viruses, and their cell entry processes involve a principal route of receptor-mediated endocytosis [28].
T80 3241-3405 Sentence denotes Membrane fusion takes place in the endosomal compartment after endocytosis, which needs additional triggers such as pH acidification or proteolytic activation [29].
T81 3406-3645 Sentence denotes Multiple cellular proteases, such as trypsin, furin, proprotein convertase (PC) family, cathepsins, transmembrane protease/serine (TMPRSS) proteases and elastase, are involved in S protein activation, which can induce membrane fusion [30].
T82 3646-3880 Sentence denotes Among them, cathepsin L, with anoptimal pH of 3.0 to 6.5, is most commonly associated with activation of a variety of CoV S proteins [30], such as SARS-CoV [19], MERS-CoV [31], HCoV-229E [32], and mouse hepatitis virus 2 (MHV-2) [33].
T83 3881-4043 Sentence denotes A recent study found that SARS-CoV-2 enters 293/hACE2 cells mainly through endocytosis, in which cathepsin L is critical for priming of SARS-CoV-2 S protein [24].
T84 4044-4393 Sentence denotes A study investigated the detailed mechanism of action of CQ/HCQ in inhibiting SARS-CoV-2 entry, and co-localization of SARS-CoV-2 with early endosomes (EEs) or endolysosomes (ELs) in VeroE6 cells, and the results showed that CQ/HCQ hampered the transport of SARS-CoV-2 from EEs to ELs, indicating that CQ/HCQ might inhibit endosomal maturation [17].
T85 4394-4657 Sentence denotes These studies revealed that the mechanism of anti-CoV activity of CQ/HCQ may involve the inhibition of the endosome acidification process, which might inactivate lysosomal proteases, thus interfering with the fusion of virus and host membranes [34,35] (Figure 1).
T86 4659-4665 Sentence denotes 4.1.3.
T87 4667-4727 Sentence denotes Effects on cell signaling pathway and host defense machinery
T88 4728-4904 Sentence denotes The mitogen-activated protein kinase (MAPK) pathway transmits signals from the cell surface to the nucleus involved in the infection of CoVs such as MHV [36] and SARS-CoV [37].
T89 4905-5044 Sentence denotes CQ could inhibit HCoV-229E replication in human embryonic lung epithelial cells (L132) through suppressing the activation of p38 MAPK [38].
T90 5045-5210 Sentence denotes Moreover, HCQ could markedly induce the production of cellular reactive oxygen species (ROS), which play an important role in the activation of innate immunity [39].
T91 5211-5368 Sentence denotes HCQ also could trigger the host defense mechanism through the mitochondrial antiviral signaling (MAVS) pathway, resulting in anti-dengue virus activity [39].
T92 5369-5529 Sentence denotes Therefore, CQ/HCQ may also exert their antiviral activity by suppressing the activation of p38 MAPK pathway and affecting the host defense machinery (Figure 1).
T93 5531-5535 Sentence denotes 4.2.
T94 5537-5599 Sentence denotes Inhibitory effect on T cell activation and cytokine production
T95 5600-5702 Sentence denotes CQ/HCQ regulate the release of various pro-inflammatory factors, which are important immunomodulators.
T96 5703-5888 Sentence denotes Intracellular alkalinization by CQ/HCQ inhibits lysosomal activity, preventing antigen processing, major histocompatibility complex (MHC) class II expression and immune activation [40].
T97 5889-5999 Sentence denotes This process can inhibit T cell activation and block expression of CD154 on the surface of CD4 + T cells [41].
T98 6000-6132 Sentence denotes CQ also reduces cytokines such as interleukin (IL)-1, IL-6 and tumor necrosis factor-α (TNF-α) produced by T cells and B cells [42].
T99 6133-6323 Sentence denotes At the same time, changes of endosomal pH can interfere with Toll-like receptor (TLR) signaling, such as TLR7 and TLR9 processing, inhibiting the activation and production of cytokines [43].
T100 6324-6475 Sentence denotes CQ/HCQ also weaken the cyclic GMP-AMP (cGAMP) synthase (cGAS) activity by inhibiting cytosolic DNA, thereby reducing type I interferon production [44].
T101 6476-6624 Sentence denotes In vitro, CQ/HCQ can also inhibit phospholipase A2, altering the metabolism of arachidonic acid, and reducing the production of prostaglandins [45].
T102 6625-6920 Sentence denotes Some clinical studies have found that high concentrations of cytokines and pro-inflammatory factors such as IL-6 and IL-10 are elevated in the plasma of critically ill patients infected with SARS-CoV-2 [46,47], suggesting that cytokine release syndrome (CRS) is associated with disease severity.
T103 6921-7047 Sentence denotes In the aspect of immune response, HCQ/CQ therefore are likely to inhibit CRS, delaying the progression of COVID-19 (Figure 1).

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T8 2149-2154 Phenotype denotes tumor http://purl.obolibrary.org/obo/HP_0002664
T9 3849-3858 Phenotype denotes hepatitis http://purl.obolibrary.org/obo/HP_0012115
T10 6063-6068 Phenotype denotes tumor http://purl.obolibrary.org/obo/HP_0002664
T11 6852-6877 Phenotype denotes cytokine release syndrome http://purl.obolibrary.org/obo/HP_0033041

2_test

Id Subject Object Predicate Lexical cue
32496926-24121034-132195666 210-212 24121034 denotes 19
32496926-24121034-132195667 394-396 24121034 denotes 19
32496926-16115318-132195668 783-785 16115318 denotes 13
32496926-18279660-132195669 2430-2432 18279660 denotes 21
32496926-16115318-132195670 2449-2451 16115318 denotes 13
32496926-31160783-132195671 2452-2454 31160783 denotes 22
32496926-23873408-132195672 2455-2457 23873408 denotes 23
32496926-32221306-132195673 2651-2653 32221306 denotes 24
32496926-15078100-132195674 2900-2902 15078100 denotes 26
32496926-9068613-132195675 2903-2905 9068613 denotes 27
32496926-22590686-132195676 3236-3238 22590686 denotes 28
32496926-22816037-132195677 3401-3403 22816037 denotes 29
32496926-25445340-132195678 3641-3643 25445340 denotes 30
32496926-25445340-132195679 3780-3782 25445340 denotes 30
32496926-24121034-132195680 3803-3805 24121034 denotes 19
32496926-23468491-132195681 3818-3820 23468491 denotes 31
32496926-18971274-132195682 3834-3836 18971274 denotes 32
32496926-16731916-132195683 3876-3878 16731916 denotes 33
32496926-32221306-132195684 4039-4041 32221306 denotes 24
32496926-32194981-132195685 4389-4391 32194981 denotes 17
32496926-28596841-132195686 4639-4641 28596841 denotes 34
32496926-14592603-132195687 4642-4644 14592603 denotes 35
32496926-12021326-132195688 4882-4884 12021326 denotes 36
32496926-16378980-132195689 4900-4902 16378980 denotes 37
32496926-18055026-132195690 5040-5042 18055026 denotes 38
32496926-25321315-132195691 5206-5208 25321315 denotes 39
32496926-25321315-132195692 5364-5366 25321315 denotes 39
32496926-2250716-132195693 5884-5886 2250716 denotes 40
32496926-28793932-132195694 5995-5997 28793932 denotes 41
32496926-16418198-132195695 6128-6130 16418198 denotes 42
32496926-18820679-132195696 6319-6321 18820679 denotes 43
32496926-25821216-132195697 6471-6473 25821216 denotes 44
32496926-4016141-132195698 6620-6622 4016141 denotes 45
32496926-31986264-132195699 6828-6830 31986264 denotes 46
32496926-32007143-132195700 6831-6833 32007143 denotes 47