PMC:7441788 / 4228-4471 JSONTXT

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T43","span":{"begin":40,"end":48},"obj":"Disease"},{"id":"T44","span":{"begin":170,"end":178},"obj":"Disease"}],"attributes":[{"id":"A43","pred":"mondo_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A44","pred":"mondo_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"he antiviral activity of CQ/HCQ against SARS-CoV had an EC50 of 4.1 (±1.0) μM and 34(±5) μM, CC50 of \u003e128 μM and CC50 \u003e 100 and SI of \u003e31 and SI\u003e3, respectively [10,11]. SARS-CoV replication was inhibited by 99% at 16 μM CQ 3 days post-infecti"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T33","span":{"begin":13,"end":21},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T34","span":{"begin":82,"end":84},"obj":"http://purl.obolibrary.org/obo/CLO_0001302"}],"text":"he antiviral activity of CQ/HCQ against SARS-CoV had an EC50 of 4.1 (±1.0) μM and 34(±5) μM, CC50 of \u003e128 μM and CC50 \u003e 100 and SI of \u003e31 and SI\u003e3, respectively [10,11]. SARS-CoV replication was inhibited by 99% at 16 μM CQ 3 days post-infecti"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T49","span":{"begin":3,"end":12},"obj":"Chemical"},{"id":"T50","span":{"begin":25,"end":27},"obj":"Chemical"},{"id":"T51","span":{"begin":128,"end":130},"obj":"Chemical"},{"id":"T52","span":{"begin":142,"end":144},"obj":"Chemical"},{"id":"T53","span":{"begin":221,"end":223},"obj":"Chemical"}],"attributes":[{"id":"A49","pred":"chebi_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"},{"id":"A50","pred":"chebi_id","subj":"T50","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"id":"A51","pred":"chebi_id","subj":"T51","obj":"http://purl.obolibrary.org/obo/CHEBI_90326"},{"id":"A52","pred":"chebi_id","subj":"T52","obj":"http://purl.obolibrary.org/obo/CHEBI_90326"},{"id":"A53","pred":"chebi_id","subj":"T53","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"}],"text":"he antiviral activity of CQ/HCQ against SARS-CoV had an EC50 of 4.1 (±1.0) μM and 34(±5) μM, CC50 of \u003e128 μM and CC50 \u003e 100 and SI of \u003e31 and SI\u003e3, respectively [10,11]. SARS-CoV replication was inhibited by 99% at 16 μM CQ 3 days post-infecti"}

{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T32","span":{"begin":25,"end":27},"obj":"Chemical"},{"id":"T33","span":{"begin":221,"end":223},"obj":"Chemical"}],"attributes":[{"id":"A32","pred":"chebi_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"id":"A33","pred":"chebi_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"}],"text":"he antiviral activity of CQ/HCQ against SARS-CoV had an EC50 of 4.1 (±1.0) μM and 34(±5) μM, CC50 of \u003e128 μM and CC50 \u003e 100 and SI of \u003e31 and SI\u003e3, respectively [10,11]. SARS-CoV replication was inhibited by 99% at 16 μM CQ 3 days post-infecti"}

{"project":"LitCovid-sample-PD-NCBITaxon","denotations":[{"id":"T43","span":{"begin":40,"end":48},"obj":"Species"},{"id":"T44","span":{"begin":170,"end":178},"obj":"Species"}],"attributes":[{"id":"A43","pred":"ncbi_taxonomy_id","subj":"T43","obj":"NCBItxid:694009"},{"id":"A44","pred":"ncbi_taxonomy_id","subj":"T44","obj":"NCBItxid:694009"}],"namespaces":[{"prefix":"NCBItxid","uri":"http://purl.bioontology.org/ontology/NCBITAXON/"}],"text":"he antiviral activity of CQ/HCQ against SARS-CoV had an EC50 of 4.1 (±1.0) μM and 34(±5) μM, CC50 of \u003e128 μM and CC50 \u003e 100 and SI of \u003e31 and SI\u003e3, respectively [10,11]. SARS-CoV replication was inhibited by 99% at 16 μM CQ 3 days post-infecti"}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"194","span":{"begin":89,"end":91},"obj":"Gene"},{"id":"197","span":{"begin":218,"end":220},"obj":"Gene"},{"id":"198","span":{"begin":106,"end":108},"obj":"Gene"},{"id":"199","span":{"begin":75,"end":77},"obj":"Gene"},{"id":"200","span":{"begin":40,"end":48},"obj":"Species"},{"id":"201","span":{"begin":170,"end":178},"obj":"Species"},{"id":"204","span":{"begin":25,"end":27},"obj":"Chemical"},{"id":"205","span":{"begin":28,"end":31},"obj":"Chemical"},{"id":"206","span":{"begin":221,"end":223},"obj":"Chemical"}],"attributes":[{"id":"A194","pred":"pubann:denotes","subj":"194","obj":"Gene:56925"},{"id":"A198","pred":"pubann:denotes","subj":"198","obj":"Gene:56925"},{"id":"A199","pred":"pubann:denotes","subj":"199","obj":"Gene:56925"},{"id":"A197","pred":"pubann:denotes","subj":"197","obj":"Gene:56925"},{"id":"A205","pred":"pubann:denotes","subj":"205","obj":"MESH:D006886"},{"id":"A206","pred":"pubann:denotes","subj":"206","obj":"MESH:D002738"},{"id":"A200","pred":"pubann:denotes","subj":"200","obj":"Tax:694009"},{"id":"A201","pred":"pubann:denotes","subj":"201","obj":"Tax:694009"},{"id":"A204","pred":"pubann:denotes","subj":"204","obj":"MESH:D002738"}],"text":"he antiviral activity of CQ/HCQ against SARS-CoV had an EC50 of 4.1 (±1.0) μM and 34(±5) μM, CC50 of \u003e128 μM and CC50 \u003e 100 and SI of \u003e31 and SI\u003e3, respectively [10,11]. SARS-CoV replication was inhibited by 99% at 16 μM CQ 3 days post-infecti"}

{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T31","span":{"begin":3,"end":12},"obj":"http://purl.obolibrary.org/obo/IDO_0000559"},{"id":"T32","span":{"begin":179,"end":190},"obj":"http://purl.obolibrary.org/obo/IDO_0000608"}],"text":"he antiviral activity of CQ/HCQ against SARS-CoV had an EC50 of 4.1 (±1.0) μM and 34(±5) μM, CC50 of \u003e128 μM and CC50 \u003e 100 and SI of \u003e31 and SI\u003e3, respectively [10,11]. SARS-CoV replication was inhibited by 99% at 16 μM CQ 3 days post-infecti"}

{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T37","span":{"begin":40,"end":48},"obj":"Disease"},{"id":"T38","span":{"begin":170,"end":178},"obj":"Disease"}],"attributes":[{"id":"A37","pred":"mondo_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A38","pred":"mondo_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"he antiviral activity of CQ/HCQ against SARS-CoV had an EC50 of 4.1 (±1.0) μM and 34(±5) μM, CC50 of \u003e128 μM and CC50 \u003e 100 and SI of \u003e31 and SI\u003e3, respectively [10,11]. SARS-CoV replication was inhibited by 99% at 16 μM CQ 3 days post-infecti"}

{"project":"LitCovid-PubTator","denotations":[{"id":"194","span":{"begin":89,"end":91},"obj":"Gene"},{"id":"197","span":{"begin":218,"end":220},"obj":"Gene"},{"id":"198","span":{"begin":106,"end":108},"obj":"Gene"},{"id":"199","span":{"begin":75,"end":77},"obj":"Gene"},{"id":"200","span":{"begin":40,"end":48},"obj":"Species"},{"id":"201","span":{"begin":170,"end":178},"obj":"Species"},{"id":"204","span":{"begin":25,"end":27},"obj":"Chemical"},{"id":"205","span":{"begin":28,"end":31},"obj":"Chemical"},{"id":"206","span":{"begin":221,"end":223},"obj":"Chemical"}],"attributes":[{"id":"A194","pred":"tao:has_database_id","subj":"194","obj":"Gene:56925"},{"id":"A197","pred":"tao:has_database_id","subj":"197","obj":"Gene:56925"},{"id":"A198","pred":"tao:has_database_id","subj":"198","obj":"Gene:56925"},{"id":"A199","pred":"tao:has_database_id","subj":"199","obj":"Gene:56925"},{"id":"A200","pred":"tao:has_database_id","subj":"200","obj":"Tax:694009"},{"id":"A201","pred":"tao:has_database_id","subj":"201","obj":"Tax:694009"},{"id":"A204","pred":"tao:has_database_id","subj":"204","obj":"MESH:D002738"},{"id":"A205","pred":"tao:has_database_id","subj":"205","obj":"MESH:D006886"},{"id":"A206","pred":"tao:has_database_id","subj":"206","obj":"MESH:D002738"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"he antiviral activity of CQ/HCQ against SARS-CoV had an EC50 of 4.1 (±1.0) μM and 34(±5) μM, CC50 of \u003e128 μM and CC50 \u003e 100 and SI of \u003e31 and SI\u003e3, respectively [10,11]. SARS-CoV replication was inhibited by 99% at 16 μM CQ 3 days post-infecti"}

{"project":"2_test","denotations":[{"id":"32496926-24841269-132195657","span":{"begin":162,"end":164},"obj":"24841269"},{"id":"32496926-16640347-132195658","span":{"begin":165,"end":167},"obj":"16640347"}],"text":"he antiviral activity of CQ/HCQ against SARS-CoV had an EC50 of 4.1 (±1.0) μM and 34(±5) μM, CC50 of \u003e128 μM and CC50 \u003e 100 and SI of \u003e31 and SI\u003e3, respectively [10,11]. SARS-CoV replication was inhibited by 99% at 16 μM CQ 3 days post-infecti"}