PMC:7441788 / 4145-4435
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7441788","sourcedb":"PMC","sourceid":"7441788","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7441788","text":"duce the virus production of 1-log and 2-log, respectively [10].\nIn VeroE6 cells, the antiviral activity of CQ/HCQ against SARS-CoV had an EC50 of 4.1 (±1.0) μM and 34(±5) μM, CC50 of \u003e128 μM and CC50 \u003e 100 and SI of \u003e31 and SI\u003e3, respectively [10,11]. SARS-CoV replication was inhibited by","tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T13","span":{"begin":75,"end":80},"obj":"Body_part"}],"attributes":[{"id":"A13","pred":"fma_id","subj":"T13","obj":"http://purl.org/sig/ont/fma/fma68646"},{"subj":"T13","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T43","span":{"begin":123,"end":131},"obj":"Disease"},{"id":"T44","span":{"begin":253,"end":261},"obj":"Disease"}],"attributes":[{"id":"A43","pred":"mondo_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A44","pred":"mondo_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"subj":"T43","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T44","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T31","span":{"begin":9,"end":14},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T32","span":{"begin":68,"end":80},"obj":"http://purl.obolibrary.org/obo/CLO_0051719"},{"id":"T33","span":{"begin":96,"end":104},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T34","span":{"begin":165,"end":167},"obj":"http://purl.obolibrary.org/obo/CLO_0001302"}],"attributes":[{"subj":"T31","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T32","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T33","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T34","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T49","span":{"begin":86,"end":95},"obj":"Chemical"},{"id":"T50","span":{"begin":108,"end":110},"obj":"Chemical"},{"id":"T51","span":{"begin":211,"end":213},"obj":"Chemical"},{"id":"T52","span":{"begin":225,"end":227},"obj":"Chemical"}],"attributes":[{"id":"A49","pred":"chebi_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"},{"id":"A50","pred":"chebi_id","subj":"T50","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"id":"A51","pred":"chebi_id","subj":"T51","obj":"http://purl.obolibrary.org/obo/CHEBI_90326"},{"id":"A52","pred":"chebi_id","subj":"T52","obj":"http://purl.obolibrary.org/obo/CHEBI_90326"},{"subj":"T49","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T50","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T51","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T52","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T32","span":{"begin":108,"end":110},"obj":"Chemical"}],"attributes":[{"id":"A32","pred":"chebi_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"subj":"T32","pred":"source","obj":"LitCovid-sample-CHEBI"}]},{"project":"LitCovid-sample-PD-NCBITaxon","denotations":[{"id":"T43","span":{"begin":123,"end":131},"obj":"Species"},{"id":"T44","span":{"begin":253,"end":261},"obj":"Species"}],"attributes":[{"id":"A43","pred":"ncbi_taxonomy_id","subj":"T43","obj":"NCBItxid:694009"},{"id":"A44","pred":"ncbi_taxonomy_id","subj":"T44","obj":"NCBItxid:694009"},{"subj":"T43","pred":"source","obj":"LitCovid-sample-PD-NCBITaxon"},{"subj":"T44","pred":"source","obj":"LitCovid-sample-PD-NCBITaxon"}],"namespaces":[{"prefix":"NCBItxid","uri":"http://purl.bioontology.org/ontology/NCBITAXON/"}]},{"project":"LitCovid-sample-sentences","denotations":[{"id":"T36","span":{"begin":65,"end":252},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T36","pred":"source","obj":"LitCovid-sample-sentences"}]},{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"194","span":{"begin":172,"end":174},"obj":"Gene"},{"id":"198","span":{"begin":189,"end":191},"obj":"Gene"},{"id":"199","span":{"begin":158,"end":160},"obj":"Gene"},{"id":"200","span":{"begin":123,"end":131},"obj":"Species"},{"id":"201","span":{"begin":253,"end":261},"obj":"Species"},{"id":"204","span":{"begin":108,"end":110},"obj":"Chemical"},{"id":"205","span":{"begin":111,"end":114},"obj":"Chemical"},{"id":"214","span":{"begin":68,"end":74},"obj":"CellLine"}],"attributes":[{"id":"A194","pred":"pubann:denotes","subj":"194","obj":"Gene:56925"},{"id":"A198","pred":"pubann:denotes","subj":"198","obj":"Gene:56925"},{"id":"A199","pred":"pubann:denotes","subj":"199","obj":"Gene:56925"},{"id":"A200","pred":"pubann:denotes","subj":"200","obj":"Tax:694009"},{"id":"A201","pred":"pubann:denotes","subj":"201","obj":"Tax:694009"},{"id":"A204","pred":"pubann:denotes","subj":"204","obj":"MESH:D002738"},{"id":"A205","pred":"pubann:denotes","subj":"205","obj":"MESH:D006886"},{"id":"A214","pred":"pubann:denotes","subj":"214","obj":"CVCL:0574"},{"subj":"194","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"198","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"199","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"200","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"201","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"204","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"205","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"214","pred":"source","obj":"LitCovid-sample-Pubtator"}]},{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T28","span":{"begin":9,"end":14},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T29","span":{"begin":15,"end":25},"obj":"http://purl.obolibrary.org/obo/IDO_0000607"},{"id":"T30","span":{"begin":75,"end":80},"obj":"http://purl.obolibrary.org/obo/CL_0000000"},{"id":"T31","span":{"begin":86,"end":95},"obj":"http://purl.obolibrary.org/obo/IDO_0000559"},{"id":"T32","span":{"begin":262,"end":273},"obj":"http://purl.obolibrary.org/obo/IDO_0000608"}],"attributes":[{"subj":"T28","pred":"source","obj":"LitCovid-sample-PD-IDO"},{"subj":"T29","pred":"source","obj":"LitCovid-sample-PD-IDO"},{"subj":"T30","pred":"source","obj":"LitCovid-sample-PD-IDO"},{"subj":"T31","pred":"source","obj":"LitCovid-sample-PD-IDO"},{"subj":"T32","pred":"source","obj":"LitCovid-sample-PD-IDO"}]},{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T13","span":{"begin":75,"end":80},"obj":"Body_part"}],"attributes":[{"id":"A13","pred":"fma_id","subj":"T13","obj":"http://purl.org/sig/ont/fma/fma68646"},{"subj":"T13","pred":"source","obj":"LitCovid-sample-PD-FMA"}]},{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T37","span":{"begin":123,"end":131},"obj":"Disease"},{"id":"T38","span":{"begin":253,"end":261},"obj":"Disease"}],"attributes":[{"id":"A37","pred":"mondo_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A38","pred":"mondo_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"subj":"T37","pred":"source","obj":"LitCovid-sample-PD-MONDO"},{"subj":"T38","pred":"source","obj":"LitCovid-sample-PD-MONDO"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"194","span":{"begin":172,"end":174},"obj":"Gene"},{"id":"198","span":{"begin":189,"end":191},"obj":"Gene"},{"id":"199","span":{"begin":158,"end":160},"obj":"Gene"},{"id":"200","span":{"begin":123,"end":131},"obj":"Species"},{"id":"201","span":{"begin":253,"end":261},"obj":"Species"},{"id":"204","span":{"begin":108,"end":110},"obj":"Chemical"},{"id":"205","span":{"begin":111,"end":114},"obj":"Chemical"},{"id":"214","span":{"begin":68,"end":74},"obj":"CellLine"}],"attributes":[{"id":"A194","pred":"tao:has_database_id","subj":"194","obj":"Gene:56925"},{"id":"A198","pred":"tao:has_database_id","subj":"198","obj":"Gene:56925"},{"id":"A199","pred":"tao:has_database_id","subj":"199","obj":"Gene:56925"},{"id":"A200","pred":"tao:has_database_id","subj":"200","obj":"Tax:694009"},{"id":"A201","pred":"tao:has_database_id","subj":"201","obj":"Tax:694009"},{"id":"A204","pred":"tao:has_database_id","subj":"204","obj":"MESH:D002738"},{"id":"A205","pred":"tao:has_database_id","subj":"205","obj":"MESH:D006886"},{"id":"A214","pred":"tao:has_database_id","subj":"214","obj":"CVCL:0574"},{"subj":"194","pred":"source","obj":"LitCovid-PubTator"},{"subj":"198","pred":"source","obj":"LitCovid-PubTator"},{"subj":"199","pred":"source","obj":"LitCovid-PubTator"},{"subj":"200","pred":"source","obj":"LitCovid-PubTator"},{"subj":"201","pred":"source","obj":"LitCovid-PubTator"},{"subj":"204","pred":"source","obj":"LitCovid-PubTator"},{"subj":"205","pred":"source","obj":"LitCovid-PubTator"},{"subj":"214","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T36","span":{"begin":65,"end":252},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T36","pred":"source","obj":"LitCovid-sentences"}]},{"project":"2_test","denotations":[{"id":"32496926-24841269-132195656","span":{"begin":60,"end":62},"obj":"24841269"},{"id":"32496926-24841269-132195657","span":{"begin":245,"end":247},"obj":"24841269"},{"id":"32496926-16640347-132195658","span":{"begin":248,"end":250},"obj":"16640347"}],"attributes":[{"subj":"32496926-24841269-132195656","pred":"source","obj":"2_test"},{"subj":"32496926-24841269-132195657","pred":"source","obj":"2_test"},{"subj":"32496926-16640347-132195658","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#c293ec","default":true},{"id":"LitCovid-PD-MONDO","color":"#93eca8"},{"id":"LitCovid-PD-CLO","color":"#ec9397"},{"id":"LitCovid-PD-CHEBI","color":"#93b1ec"},{"id":"LitCovid-sample-CHEBI","color":"#cbec93"},{"id":"LitCovid-sample-PD-NCBITaxon","color":"#ec93e5"},{"id":"LitCovid-sample-sentences","color":"#93ecd8"},{"id":"LitCovid-sample-Pubtator","color":"#ecbe93"},{"id":"LitCovid-sample-PD-IDO","color":"#a493ec"},{"id":"LitCovid-sample-PD-FMA","color":"#9bec93"},{"id":"LitCovid-sample-PD-MONDO","color":"#ec93b5"},{"id":"LitCovid-PubTator","color":"#93cfec"},{"id":"LitCovid-sentences","color":"#e9ec93"},{"id":"2_test","color":"#d593ec"}]}]}}