PMC:7441788 / 40341-40684 JSONTXT

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T167","span":{"begin":28,"end":39},"obj":"Disease"},{"id":"T168","span":{"begin":95,"end":104},"obj":"Disease"},{"id":"T169","span":{"begin":242,"end":250},"obj":"Disease"},{"id":"T170","span":{"begin":288,"end":296},"obj":"Disease"}],"attributes":[{"id":"A167","pred":"mondo_id","subj":"T167","obj":"http://purl.obolibrary.org/obo/MONDO_0017941"},{"id":"A168","pred":"mondo_id","subj":"T168","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A169","pred":"mondo_id","subj":"T169","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A170","pred":"mondo_id","subj":"T170","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":" beneficial results against chikungunya virus in vitro, but in animal models it aggravates the infection and lacks therapeutic effect [73]. More importantly, in recent studies the use of HCQ did not show any favorable effect on patients with COVID-19 and high-dose CQ treatment of severe COVID-19 patients may even increase the risks of mortal"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T296","span":{"begin":40,"end":45},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T297","span":{"begin":63,"end":69},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_33208"}],"text":" beneficial results against chikungunya virus in vitro, but in animal models it aggravates the infection and lacks therapeutic effect [73]. More importantly, in recent studies the use of HCQ did not show any favorable effect on patients with COVID-19 and high-dose CQ treatment of severe COVID-19 patients may even increase the risks of mortal"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T416","span":{"begin":265,"end":267},"obj":"Chemical"}],"attributes":[{"id":"A416","pred":"chebi_id","subj":"T416","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"}],"text":" beneficial results against chikungunya virus in vitro, but in animal models it aggravates the infection and lacks therapeutic effect [73]. More importantly, in recent studies the use of HCQ did not show any favorable effect on patients with COVID-19 and high-dose CQ treatment of severe COVID-19 patients may even increase the risks of mortal"}

{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T247","span":{"begin":265,"end":267},"obj":"Chemical"}],"attributes":[{"id":"A247","pred":"chebi_id","subj":"T247","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"}],"text":" beneficial results against chikungunya virus in vitro, but in animal models it aggravates the infection and lacks therapeutic effect [73]. More importantly, in recent studies the use of HCQ did not show any favorable effect on patients with COVID-19 and high-dose CQ treatment of severe COVID-19 patients may even increase the risks of mortal"}

{"project":"LitCovid-sample-PD-NCBITaxon","denotations":[{"id":"T148","span":{"begin":28,"end":45},"obj":"Species"},{"id":"T149","span":{"begin":242,"end":250},"obj":"Species"},{"id":"T150","span":{"begin":288,"end":296},"obj":"Species"}],"attributes":[{"id":"A148","pred":"ncbi_taxonomy_id","subj":"T148","obj":"NCBItxid:37124"},{"id":"A149","pred":"ncbi_taxonomy_id","subj":"T149","obj":"NCBItxid:2697049"},{"id":"A150","pred":"ncbi_taxonomy_id","subj":"T150","obj":"NCBItxid:2697049"}],"namespaces":[{"prefix":"NCBItxid","uri":"http://purl.bioontology.org/ontology/NCBITAXON/"}],"text":" beneficial results against chikungunya virus in vitro, but in animal models it aggravates the infection and lacks therapeutic effect [73]. More importantly, in recent studies the use of HCQ did not show any favorable effect on patients with COVID-19 and high-dose CQ treatment of severe COVID-19 patients may even increase the risks of mortal"}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"1488","span":{"begin":28,"end":45},"obj":"Species"},{"id":"1489","span":{"begin":228,"end":236},"obj":"Species"},{"id":"1490","span":{"begin":297,"end":305},"obj":"Species"},{"id":"1503","span":{"begin":187,"end":190},"obj":"Chemical"},{"id":"1504","span":{"begin":265,"end":267},"obj":"Chemical"},{"id":"1523","span":{"begin":95,"end":104},"obj":"Disease"},{"id":"1524","span":{"begin":242,"end":250},"obj":"Disease"},{"id":"1525","span":{"begin":288,"end":296},"obj":"Disease"}],"attributes":[{"id":"A1490","pred":"pubann:denotes","subj":"1490","obj":"Tax:9606"},{"id":"A1503","pred":"pubann:denotes","subj":"1503","obj":"MESH:D006886"},{"id":"A1504","pred":"pubann:denotes","subj":"1504","obj":"MESH:D002738"},{"id":"A1524","pred":"pubann:denotes","subj":"1524","obj":"MESH:C000657245"},{"id":"A1489","pred":"pubann:denotes","subj":"1489","obj":"Tax:9606"},{"id":"A1523","pred":"pubann:denotes","subj":"1523","obj":"MESH:D007239"},{"id":"A1525","pred":"pubann:denotes","subj":"1525","obj":"MESH:C000657245"},{"id":"A1488","pred":"pubann:denotes","subj":"1488","obj":"Tax:37124"}],"text":" beneficial results against chikungunya virus in vitro, but in animal models it aggravates the infection and lacks therapeutic effect [73]. More importantly, in recent studies the use of HCQ did not show any favorable effect on patients with COVID-19 and high-dose CQ treatment of severe COVID-19 patients may even increase the risks of mortal"}

{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T151","span":{"begin":40,"end":45},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T152","span":{"begin":95,"end":104},"obj":"http://purl.obolibrary.org/obo/IDO_0000586"}],"text":" beneficial results against chikungunya virus in vitro, but in animal models it aggravates the infection and lacks therapeutic effect [73]. More importantly, in recent studies the use of HCQ did not show any favorable effect on patients with COVID-19 and high-dose CQ treatment of severe COVID-19 patients may even increase the risks of mortal"}

{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T159","span":{"begin":28,"end":39},"obj":"Disease"},{"id":"T160","span":{"begin":95,"end":104},"obj":"Disease"},{"id":"T161","span":{"begin":242,"end":250},"obj":"Disease"},{"id":"T162","span":{"begin":288,"end":296},"obj":"Disease"}],"attributes":[{"id":"A159","pred":"mondo_id","subj":"T159","obj":"http://purl.obolibrary.org/obo/MONDO_0017941"},{"id":"A160","pred":"mondo_id","subj":"T160","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A161","pred":"mondo_id","subj":"T161","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A162","pred":"mondo_id","subj":"T162","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":" beneficial results against chikungunya virus in vitro, but in animal models it aggravates the infection and lacks therapeutic effect [73]. More importantly, in recent studies the use of HCQ did not show any favorable effect on patients with COVID-19 and high-dose CQ treatment of severe COVID-19 patients may even increase the risks of mortal"}

{"project":"LitCovid-PubTator","denotations":[{"id":"1488","span":{"begin":28,"end":45},"obj":"Species"},{"id":"1489","span":{"begin":228,"end":236},"obj":"Species"},{"id":"1490","span":{"begin":297,"end":305},"obj":"Species"},{"id":"1503","span":{"begin":187,"end":190},"obj":"Chemical"},{"id":"1504","span":{"begin":265,"end":267},"obj":"Chemical"},{"id":"1523","span":{"begin":95,"end":104},"obj":"Disease"},{"id":"1524","span":{"begin":242,"end":250},"obj":"Disease"},{"id":"1525","span":{"begin":288,"end":296},"obj":"Disease"}],"attributes":[{"id":"A1488","pred":"tao:has_database_id","subj":"1488","obj":"Tax:37124"},{"id":"A1489","pred":"tao:has_database_id","subj":"1489","obj":"Tax:9606"},{"id":"A1490","pred":"tao:has_database_id","subj":"1490","obj":"Tax:9606"},{"id":"A1503","pred":"tao:has_database_id","subj":"1503","obj":"MESH:D006886"},{"id":"A1504","pred":"tao:has_database_id","subj":"1504","obj":"MESH:D002738"},{"id":"A1523","pred":"tao:has_database_id","subj":"1523","obj":"MESH:D007239"},{"id":"A1524","pred":"tao:has_database_id","subj":"1524","obj":"MESH:C000657245"},{"id":"A1525","pred":"tao:has_database_id","subj":"1525","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":" beneficial results against chikungunya virus in vitro, but in animal models it aggravates the infection and lacks therapeutic effect [73]. More importantly, in recent studies the use of HCQ did not show any favorable effect on patients with COVID-19 and high-dose CQ treatment of severe COVID-19 patients may even increase the risks of mortal"}