PMC:7441788 / 39290-39626 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T128","span":{"begin":217,"end":225},"obj":"Body_part"}],"attributes":[{"id":"A128","pred":"fma_id","subj":"T128","obj":"http://purl.org/sig/ont/fma/fma67180"}],"text":"ntion. CQ/HCQ have diverse biological activities, and their mechanisms against CoVs including SARS-CoV-2 are not yet fully clarified. Current studies show that CQ/HCQ can prevent receptor recognition by CoVs, inhibit endosome acidification, which interferes membrane fusion, and exhibit immunomodulatory activity. These multiple mechani"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T160","span":{"begin":94,"end":102},"obj":"Disease"}],"attributes":[{"id":"A160","pred":"mondo_id","subj":"T160","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"ntion. CQ/HCQ have diverse biological activities, and their mechanisms against CoVs including SARS-CoV-2 are not yet fully clarified. Current studies show that CQ/HCQ can prevent receptor recognition by CoVs, inhibit endosome acidification, which interferes membrane fusion, and exhibit immunomodulatory activity. These multiple mechani"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T285","span":{"begin":38,"end":48},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T286","span":{"begin":258,"end":266},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T287","span":{"begin":304,"end":312},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"ntion. CQ/HCQ have diverse biological activities, and their mechanisms against CoVs including SARS-CoV-2 are not yet fully clarified. Current studies show that CQ/HCQ can prevent receptor recognition by CoVs, inhibit endosome acidification, which interferes membrane fusion, and exhibit immunomodulatory activity. These multiple mechani"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T409","span":{"begin":7,"end":9},"obj":"Chemical"},{"id":"T410","span":{"begin":160,"end":162},"obj":"Chemical"}],"attributes":[{"id":"A409","pred":"chebi_id","subj":"T409","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"id":"A410","pred":"chebi_id","subj":"T410","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"}],"text":"ntion. CQ/HCQ have diverse biological activities, and their mechanisms against CoVs including SARS-CoV-2 are not yet fully clarified. Current studies show that CQ/HCQ can prevent receptor recognition by CoVs, inhibit endosome acidification, which interferes membrane fusion, and exhibit immunomodulatory activity. These multiple mechani"}

{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T240","span":{"begin":7,"end":9},"obj":"Chemical"},{"id":"T241","span":{"begin":160,"end":162},"obj":"Chemical"}],"attributes":[{"id":"A240","pred":"chebi_id","subj":"T240","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"id":"A241","pred":"chebi_id","subj":"T241","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"}],"text":"ntion. CQ/HCQ have diverse biological activities, and their mechanisms against CoVs including SARS-CoV-2 are not yet fully clarified. Current studies show that CQ/HCQ can prevent receptor recognition by CoVs, inhibit endosome acidification, which interferes membrane fusion, and exhibit immunomodulatory activity. These multiple mechani"}

{"project":"LitCovid-sample-PD-NCBITaxon","denotations":[{"id":"T140","span":{"begin":94,"end":104},"obj":"Species"}],"attributes":[{"id":"A140","pred":"ncbi_taxonomy_id","subj":"T140","obj":"NCBItxid:2697049"}],"namespaces":[{"prefix":"NCBItxid","uri":"http://purl.bioontology.org/ontology/NCBITAXON/"}],"text":"ntion. CQ/HCQ have diverse biological activities, and their mechanisms against CoVs including SARS-CoV-2 are not yet fully clarified. Current studies show that CQ/HCQ can prevent receptor recognition by CoVs, inhibit endosome acidification, which interferes membrane fusion, and exhibit immunomodulatory activity. These multiple mechani"}

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T269","span":{"begin":7,"end":133},"obj":"Sentence"},{"id":"T270","span":{"begin":134,"end":313},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"ntion. CQ/HCQ have diverse biological activities, and their mechanisms against CoVs including SARS-CoV-2 are not yet fully clarified. Current studies show that CQ/HCQ can prevent receptor recognition by CoVs, inhibit endosome acidification, which interferes membrane fusion, and exhibit immunomodulatory activity. These multiple mechani"}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"1480","span":{"begin":79,"end":83},"obj":"Species"},{"id":"1481","span":{"begin":94,"end":104},"obj":"Species"},{"id":"1482","span":{"begin":203,"end":207},"obj":"Species"},{"id":"1497","span":{"begin":7,"end":13},"obj":"Chemical"},{"id":"1498","span":{"begin":160,"end":166},"obj":"Chemical"}],"attributes":[{"id":"A1480","pred":"pubann:denotes","subj":"1480","obj":"Tax:11118"},{"id":"A1481","pred":"pubann:denotes","subj":"1481","obj":"Tax:2697049"},{"id":"A1482","pred":"pubann:denotes","subj":"1482","obj":"Tax:11118"}],"text":"ntion. CQ/HCQ have diverse biological activities, and their mechanisms against CoVs including SARS-CoV-2 are not yet fully clarified. Current studies show that CQ/HCQ can prevent receptor recognition by CoVs, inhibit endosome acidification, which interferes membrane fusion, and exhibit immunomodulatory activity. These multiple mechani"}

{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T127","span":{"begin":217,"end":225},"obj":"Body_part"}],"attributes":[{"id":"A127","pred":"fma_id","subj":"T127","obj":"http://purl.org/sig/ont/fma/fma67180"}],"text":"ntion. CQ/HCQ have diverse biological activities, and their mechanisms against CoVs including SARS-CoV-2 are not yet fully clarified. Current studies show that CQ/HCQ can prevent receptor recognition by CoVs, inhibit endosome acidification, which interferes membrane fusion, and exhibit immunomodulatory activity. These multiple mechani"}

{"project":"LitCovid-sample-PD-GO-BP-0","denotations":[{"id":"T77","span":{"begin":226,"end":239},"obj":"http://purl.obolibrary.org/obo/GO_0045851"},{"id":"T78","span":{"begin":258,"end":273},"obj":"http://purl.obolibrary.org/obo/GO_0061025"}],"text":"ntion. CQ/HCQ have diverse biological activities, and their mechanisms against CoVs including SARS-CoV-2 are not yet fully clarified. Current studies show that CQ/HCQ can prevent receptor recognition by CoVs, inhibit endosome acidification, which interferes membrane fusion, and exhibit immunomodulatory activity. These multiple mechani"}

{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T152","span":{"begin":94,"end":104},"obj":"Disease"}],"attributes":[{"id":"A152","pred":"mondo_id","subj":"T152","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"ntion. CQ/HCQ have diverse biological activities, and their mechanisms against CoVs including SARS-CoV-2 are not yet fully clarified. Current studies show that CQ/HCQ can prevent receptor recognition by CoVs, inhibit endosome acidification, which interferes membrane fusion, and exhibit immunomodulatory activity. These multiple mechani"}

{"project":"LitCovid-sample-GO-BP","denotations":[{"id":"T68","span":{"begin":226,"end":239},"obj":"http://purl.obolibrary.org/obo/GO_0045851"},{"id":"T69","span":{"begin":258,"end":273},"obj":"http://purl.obolibrary.org/obo/GO_0061025"}],"text":"ntion. CQ/HCQ have diverse biological activities, and their mechanisms against CoVs including SARS-CoV-2 are not yet fully clarified. Current studies show that CQ/HCQ can prevent receptor recognition by CoVs, inhibit endosome acidification, which interferes membrane fusion, and exhibit immunomodulatory activity. These multiple mechani"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T64","span":{"begin":226,"end":239},"obj":"http://purl.obolibrary.org/obo/GO_0045851"},{"id":"T65","span":{"begin":258,"end":273},"obj":"http://purl.obolibrary.org/obo/GO_0061025"}],"text":"ntion. CQ/HCQ have diverse biological activities, and their mechanisms against CoVs including SARS-CoV-2 are not yet fully clarified. Current studies show that CQ/HCQ can prevent receptor recognition by CoVs, inhibit endosome acidification, which interferes membrane fusion, and exhibit immunomodulatory activity. These multiple mechani"}

{"project":"LitCovid-PubTator","denotations":[{"id":"1480","span":{"begin":79,"end":83},"obj":"Species"},{"id":"1481","span":{"begin":94,"end":104},"obj":"Species"},{"id":"1482","span":{"begin":203,"end":207},"obj":"Species"},{"id":"1497","span":{"begin":7,"end":13},"obj":"Chemical"},{"id":"1498","span":{"begin":160,"end":166},"obj":"Chemical"}],"attributes":[{"id":"A1480","pred":"tao:has_database_id","subj":"1480","obj":"Tax:11118"},{"id":"A1481","pred":"tao:has_database_id","subj":"1481","obj":"Tax:2697049"},{"id":"A1482","pred":"tao:has_database_id","subj":"1482","obj":"Tax:11118"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"ntion. CQ/HCQ have diverse biological activities, and their mechanisms against CoVs including SARS-CoV-2 are not yet fully clarified. Current studies show that CQ/HCQ can prevent receptor recognition by CoVs, inhibit endosome acidification, which interferes membrane fusion, and exhibit immunomodulatory activity. These multiple mechani"}

{"project":"LitCovid-sentences","denotations":[{"id":"T269","span":{"begin":7,"end":133},"obj":"Sentence"},{"id":"T270","span":{"begin":134,"end":313},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"ntion. CQ/HCQ have diverse biological activities, and their mechanisms against CoVs including SARS-CoV-2 are not yet fully clarified. Current studies show that CQ/HCQ can prevent receptor recognition by CoVs, inhibit endosome acidification, which interferes membrane fusion, and exhibit immunomodulatory activity. These multiple mechani"}