PMC:7441788 / 19721-20203 JSONTXT

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T185","span":{"begin":24,"end":29},"obj":"http://purl.obolibrary.org/obo/CLO_0007225"},{"id":"T186","span":{"begin":252,"end":257},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T187","span":{"begin":261,"end":264},"obj":"http://purl.obolibrary.org/obo/CLO_0001000"},{"id":"T188","span":{"begin":286,"end":291},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"}],"text":"Gautret et al.[57] Open label, nonrandom cohort study HCQ group: n = 12; HCQ＋azithromycin group: n = 6; control group: n = 12 HCQ (200 mg/3 times/day for 10 days) HCQ alone or in combination with azithromycin could effectively eliminate nasopharyngeal virus in 3–5 days. Nasopharyngeal virus determination was used as main endpoint. Small sample size; Six patients dropped out due to critical illness or intolerance to the drug; Lack of clinical outcomes; Limited follow-up results."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T240","span":{"begin":24,"end":29},"obj":"Chemical"},{"id":"T241","span":{"begin":58,"end":63},"obj":"Chemical"},{"id":"T242","span":{"begin":77,"end":89},"obj":"Chemical"},{"id":"T243","span":{"begin":90,"end":95},"obj":"Chemical"},{"id":"T244","span":{"begin":112,"end":117},"obj":"Chemical"},{"id":"T245","span":{"begin":196,"end":208},"obj":"Chemical"},{"id":"T246","span":{"begin":423,"end":427},"obj":"Chemical"}],"attributes":[{"id":"A240","pred":"chebi_id","subj":"T240","obj":"http://purl.obolibrary.org/obo/CHEBI_35209"},{"id":"A241","pred":"chebi_id","subj":"T241","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"},{"id":"A242","pred":"chebi_id","subj":"T242","obj":"http://purl.obolibrary.org/obo/CHEBI_2955"},{"id":"A243","pred":"chebi_id","subj":"T243","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"},{"id":"A244","pred":"chebi_id","subj":"T244","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"},{"id":"A245","pred":"chebi_id","subj":"T245","obj":"http://purl.obolibrary.org/obo/CHEBI_2955"},{"id":"A246","pred":"chebi_id","subj":"T246","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"}],"text":"Gautret et al.[57] Open label, nonrandom cohort study HCQ group: n = 12; HCQ＋azithromycin group: n = 6; control group: n = 12 HCQ (200 mg/3 times/day for 10 days) HCQ alone or in combination with azithromycin could effectively eliminate nasopharyngeal virus in 3–5 days. Nasopharyngeal virus determination was used as main endpoint. Small sample size; Six patients dropped out due to critical illness or intolerance to the drug; Lack of clinical outcomes; Limited follow-up results."}

{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T137","span":{"begin":77,"end":89},"obj":"Chemical"},{"id":"T138","span":{"begin":196,"end":208},"obj":"Chemical"}],"attributes":[{"id":"A137","pred":"chebi_id","subj":"T137","obj":"http://purl.obolibrary.org/obo/CHEBI_2955"},{"id":"A138","pred":"chebi_id","subj":"T138","obj":"http://purl.obolibrary.org/obo/CHEBI_2955"}],"text":"Gautret et al.[57] Open label, nonrandom cohort study HCQ group: n = 12; HCQ＋azithromycin group: n = 6; control group: n = 12 HCQ (200 mg/3 times/day for 10 days) HCQ alone or in combination with azithromycin could effectively eliminate nasopharyngeal virus in 3–5 days. Nasopharyngeal virus determination was used as main endpoint. Small sample size; Six patients dropped out due to critical illness or intolerance to the drug; Lack of clinical outcomes; Limited follow-up results."}

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T148","span":{"begin":0,"end":270},"obj":"Sentence"},{"id":"T149","span":{"begin":271,"end":332},"obj":"Sentence"},{"id":"T150","span":{"begin":333,"end":482},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Gautret et al.[57] Open label, nonrandom cohort study HCQ group: n = 12; HCQ＋azithromycin group: n = 6; control group: n = 12 HCQ (200 mg/3 times/day for 10 days) HCQ alone or in combination with azithromycin could effectively eliminate nasopharyngeal virus in 3–5 days. Nasopharyngeal virus determination was used as main endpoint. Small sample size; Six patients dropped out due to critical illness or intolerance to the drug; Lack of clinical outcomes; Limited follow-up results."}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"686","span":{"begin":54,"end":57},"obj":"Chemical"},{"id":"687","span":{"begin":73,"end":76},"obj":"Chemical"}],"attributes":[{"id":"A686","pred":"pubann:denotes","subj":"686","obj":"MESH:D006886"},{"id":"A687","pred":"pubann:denotes","subj":"687","obj":"MESH:D006886"}],"text":"Gautret et al.[57] Open label, nonrandom cohort study HCQ group: n = 12; HCQ＋azithromycin group: n = 6; control group: n = 12 HCQ (200 mg/3 times/day for 10 days) HCQ alone or in combination with azithromycin could effectively eliminate nasopharyngeal virus in 3–5 days. Nasopharyngeal virus determination was used as main endpoint. Small sample size; Six patients dropped out due to critical illness or intolerance to the drug; Lack of clinical outcomes; Limited follow-up results."}

{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T122","span":{"begin":252,"end":257},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T123","span":{"begin":286,"end":291},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"}],"text":"Gautret et al.[57] Open label, nonrandom cohort study HCQ group: n = 12; HCQ＋azithromycin group: n = 6; control group: n = 12 HCQ (200 mg/3 times/day for 10 days) HCQ alone or in combination with azithromycin could effectively eliminate nasopharyngeal virus in 3–5 days. Nasopharyngeal virus determination was used as main endpoint. Small sample size; Six patients dropped out due to critical illness or intolerance to the drug; Lack of clinical outcomes; Limited follow-up results."}

{"project":"LitCovid-PubTator","denotations":[{"id":"686","span":{"begin":54,"end":57},"obj":"Chemical"},{"id":"687","span":{"begin":73,"end":76},"obj":"Chemical"}],"attributes":[{"id":"A686","pred":"tao:has_database_id","subj":"686","obj":"MESH:D006886"},{"id":"A687","pred":"tao:has_database_id","subj":"687","obj":"MESH:D006886"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Gautret et al.[57] Open label, nonrandom cohort study HCQ group: n = 12; HCQ＋azithromycin group: n = 6; control group: n = 12 HCQ (200 mg/3 times/day for 10 days) HCQ alone or in combination with azithromycin could effectively eliminate nasopharyngeal virus in 3–5 days. Nasopharyngeal virus determination was used as main endpoint. Small sample size; Six patients dropped out due to critical illness or intolerance to the drug; Lack of clinical outcomes; Limited follow-up results."}

{"project":"LitCovid-sentences","denotations":[{"id":"T148","span":{"begin":0,"end":270},"obj":"Sentence"},{"id":"T149","span":{"begin":271,"end":332},"obj":"Sentence"},{"id":"T150","span":{"begin":333,"end":482},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Gautret et al.[57] Open label, nonrandom cohort study HCQ group: n = 12; HCQ＋azithromycin group: n = 6; control group: n = 12 HCQ (200 mg/3 times/day for 10 days) HCQ alone or in combination with azithromycin could effectively eliminate nasopharyngeal virus in 3–5 days. Nasopharyngeal virus determination was used as main endpoint. Small sample size; Six patients dropped out due to critical illness or intolerance to the drug; Lack of clinical outcomes; Limited follow-up results."}