PMC:7441788 / 14051-14346
Annnotations
LitCovid-PD-FMA-UBERON
{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T100","span":{"begin":61,"end":70},"obj":"Body_part"},{"id":"T101","span":{"begin":108,"end":110},"obj":"Body_part"},{"id":"T102","span":{"begin":117,"end":119},"obj":"Body_part"},{"id":"T103","span":{"begin":143,"end":149},"obj":"Body_part"},{"id":"T104","span":{"begin":227,"end":235},"obj":"Body_part"}],"attributes":[{"id":"A100","pred":"fma_id","subj":"T100","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A101","pred":"fma_id","subj":"T101","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A102","pred":"fma_id","subj":"T102","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A103","pred":"fma_id","subj":"T103","obj":"http://purl.org/sig/ont/fma/fma62970"},{"id":"A104","pred":"fma_id","subj":"T104","obj":"http://purl.org/sig/ont/fma/fma84050"}],"text":"Some clinical studies have found that high concentrations of cytokines and pro-inflammatory factors such as IL-6 and IL-10 are elevated in the plasma of critically ill patients infected with SARS-CoV-2 [46,47], suggesting that cytokine release syndrome (CRS) is associated with disease severity."}
LitCovid-PD-MONDO
{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T87","span":{"begin":191,"end":199},"obj":"Disease"},{"id":"T88","span":{"begin":254,"end":257},"obj":"Disease"}],"attributes":[{"id":"A87","pred":"mondo_id","subj":"T87","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A88","pred":"mondo_id","subj":"T88","obj":"http://purl.obolibrary.org/obo/MONDO_0007399"},{"id":"A89","pred":"mondo_id","subj":"T88","obj":"http://purl.obolibrary.org/obo/MONDO_0017361"}],"text":"Some clinical studies have found that high concentrations of cytokines and pro-inflammatory factors such as IL-6 and IL-10 are elevated in the plasma of critically ill patients infected with SARS-CoV-2 [46,47], suggesting that cytokine release syndrome (CRS) is associated with disease severity."}
LitCovid-PD-CLO
{"project":"LitCovid-PD-CLO","denotations":[{"id":"T166","span":{"begin":143,"end":149},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"}],"text":"Some clinical studies have found that high concentrations of cytokines and pro-inflammatory factors such as IL-6 and IL-10 are elevated in the plasma of critically ill patients infected with SARS-CoV-2 [46,47], suggesting that cytokine release syndrome (CRS) is associated with disease severity."}
LitCovid-PD-CHEBI
{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T188","span":{"begin":108,"end":110},"obj":"Chemical"},{"id":"T190","span":{"begin":117,"end":119},"obj":"Chemical"}],"attributes":[{"id":"A188","pred":"chebi_id","subj":"T188","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A189","pred":"chebi_id","subj":"T188","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A190","pred":"chebi_id","subj":"T190","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A191","pred":"chebi_id","subj":"T190","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"}],"text":"Some clinical studies have found that high concentrations of cytokines and pro-inflammatory factors such as IL-6 and IL-10 are elevated in the plasma of critically ill patients infected with SARS-CoV-2 [46,47], suggesting that cytokine release syndrome (CRS) is associated with disease severity."}
LitCovid-sample-PD-NCBITaxon
{"project":"LitCovid-sample-PD-NCBITaxon","denotations":[{"id":"T95","span":{"begin":191,"end":201},"obj":"Species"}],"attributes":[{"id":"A95","pred":"ncbi_taxonomy_id","subj":"T95","obj":"NCBItxid:2697049"}],"namespaces":[{"prefix":"NCBItxid","uri":"http://purl.bioontology.org/ontology/NCBITAXON/"}],"text":"Some clinical studies have found that high concentrations of cytokines and pro-inflammatory factors such as IL-6 and IL-10 are elevated in the plasma of critically ill patients infected with SARS-CoV-2 [46,47], suggesting that cytokine release syndrome (CRS) is associated with disease severity."}
LitCovid-sample-sentences
{"project":"LitCovid-sample-sentences","denotations":[{"id":"T102","span":{"begin":0,"end":295},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Some clinical studies have found that high concentrations of cytokines and pro-inflammatory factors such as IL-6 and IL-10 are elevated in the plasma of critically ill patients infected with SARS-CoV-2 [46,47], suggesting that cytokine release syndrome (CRS) is associated with disease severity."}
LitCovid-sample-Pubtator
{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"531","span":{"begin":108,"end":112},"obj":"Gene"},{"id":"532","span":{"begin":117,"end":122},"obj":"Gene"},{"id":"533","span":{"begin":168,"end":176},"obj":"Species"},{"id":"534","span":{"begin":191,"end":201},"obj":"Species"},{"id":"545","span":{"begin":153,"end":167},"obj":"Disease"},{"id":"546","span":{"begin":177,"end":185},"obj":"Disease"},{"id":"547","span":{"begin":254,"end":257},"obj":"Disease"}],"attributes":[{"id":"A531","pred":"pubann:denotes","subj":"531","obj":"Gene:3569"},{"id":"A532","pred":"pubann:denotes","subj":"532","obj":"Gene:3586"},{"id":"A533","pred":"pubann:denotes","subj":"533","obj":"Tax:9606"},{"id":"A534","pred":"pubann:denotes","subj":"534","obj":"Tax:2697049"},{"id":"A545","pred":"pubann:denotes","subj":"545","obj":"MESH:D016638"},{"id":"A546","pred":"pubann:denotes","subj":"546","obj":"MESH:D007239"},{"id":"A547","pred":"pubann:denotes","subj":"547","obj":"MESH:D003398"}],"text":"Some clinical studies have found that high concentrations of cytokines and pro-inflammatory factors such as IL-6 and IL-10 are elevated in the plasma of critically ill patients infected with SARS-CoV-2 [46,47], suggesting that cytokine release syndrome (CRS) is associated with disease severity."}
LitCovid-sample-UniProt
{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T1136","span":{"begin":108,"end":112},"obj":"Protein"},{"id":"T1180","span":{"begin":117,"end":122},"obj":"Protein"}],"attributes":[{"id":"A1136","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q9XT80"},{"id":"A1137","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q9UCU4"},{"id":"A1138","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q9UCU3"},{"id":"A1139","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q9UCU2"},{"id":"A1140","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q9MZR1"},{"id":"A1141","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q9MYZ7"},{"id":"A1142","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q95KN6"},{"id":"A1143","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q95181"},{"id":"A1144","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q90YI0"},{"id":"A1145","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q8MKH0"},{"id":"A1146","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q8BN26"},{"id":"A1147","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q865X6"},{"id":"A1148","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q865W7"},{"id":"A1149","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q6V919"},{"id":"A1150","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q6L6X6"},{"id":"A1151","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q5I6E3"},{"id":"A1152","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q3UCQ0"},{"id":"A1153","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q2MH06"},{"id":"A1154","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q28819"},{"id":"A1155","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q28747"},{"id":"A1156","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q28319"},{"id":"A1157","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q25BC2"},{"id":"A1158","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q0PW36"},{"id":"A1159","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q0GGL7"},{"id":"A1160","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/Q08DT2"},{"id":"A1161","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/P79341"},{"id":"A1162","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/P51494"},{"id":"A1163","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/P46650"},{"id":"A1164","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/P41693"},{"id":"A1165","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/P41683"},{"id":"A1166","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/P41323"},{"id":"A1167","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/P29455"},{"id":"A1168","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/P26893"},{"id":"A1169","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/P26892"},{"id":"A1170","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/P20607"},{"id":"A1171","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/P08505"},{"id":"A1172","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/P05231"},{"id":"A1173","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/O46568"},{"id":"A1174","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/O35736"},{"id":"A1175","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/O19007"},{"id":"A1176","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/B6CKP4"},{"id":"A1177","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/A9QWQ9"},{"id":"A1178","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/A3FBE9"},{"id":"A1179","pred":"uniprot_id","subj":"T1136","obj":"https://www.uniprot.org/uniprot/A0S0B0"},{"id":"A1180","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/Q9Z1Y5"},{"id":"A1181","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/Q9TSJ7"},{"id":"A1182","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/Q9TSJ4"},{"id":"A1183","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/Q9JHK7"},{"id":"A1184","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/Q8MKG9"},{"id":"A1185","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/Q865X4"},{"id":"A1186","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/Q6A2H5"},{"id":"A1187","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/Q6A2H4"},{"id":"A1188","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/Q63263"},{"id":"A1189","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/Q5Q0V6"},{"id":"A1190","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/Q2PE73"},{"id":"A1191","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/Q29408"},{"id":"A1192","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/Q29055"},{"id":"A1193","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/Q28374"},{"id":"A1194","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/Q25BC1"},{"id":"A1195","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/Q1W5D6"},{"id":"A1196","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/Q0Z972"},{"id":"A1197","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/Q0VBJ1"},{"id":"A1198","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/P79338"},{"id":"A1199","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/P55029"},{"id":"A1200","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/P51746"},{"id":"A1201","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/P51497"},{"id":"A1202","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/P51496"},{"id":"A1203","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/P48411"},{"id":"A1204","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/P47965"},{"id":"A1205","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/P46651"},{"id":"A1206","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/P43480"},{"id":"A1207","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/P29456"},{"id":"A1208","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/P22301"},{"id":"A1209","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/P18893"},{"id":"A1210","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/O97798"},{"id":"A1211","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/O46673"},{"id":"A1212","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/A9QWR2"},{"id":"A1213","pred":"uniprot_id","subj":"T1180","obj":"https://www.uniprot.org/uniprot/A2T6Z6"}],"text":"Some clinical studies have found that high concentrations of cytokines and pro-inflammatory factors such as IL-6 and IL-10 are elevated in the plasma of critically ill patients infected with SARS-CoV-2 [46,47], suggesting that cytokine release syndrome (CRS) is associated with disease severity."}
LitCovid-sample-PD-IDO
{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T112","span":{"begin":177,"end":185},"obj":"http://purl.obolibrary.org/obo/IDO_0000586"},{"id":"T113","span":{"begin":278,"end":285},"obj":"http://purl.obolibrary.org/obo/OGMS_0000031"}],"text":"Some clinical studies have found that high concentrations of cytokines and pro-inflammatory factors such as IL-6 and IL-10 are elevated in the plasma of critically ill patients infected with SARS-CoV-2 [46,47], suggesting that cytokine release syndrome (CRS) is associated with disease severity."}
LitCovid-sample-PD-FMA
{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T99","span":{"begin":61,"end":70},"obj":"Body_part"},{"id":"T100","span":{"begin":108,"end":110},"obj":"Body_part"},{"id":"T101","span":{"begin":117,"end":119},"obj":"Body_part"},{"id":"T102","span":{"begin":143,"end":149},"obj":"Body_part"},{"id":"T103","span":{"begin":227,"end":235},"obj":"Body_part"}],"attributes":[{"id":"A99","pred":"fma_id","subj":"T99","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A100","pred":"fma_id","subj":"T100","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A101","pred":"fma_id","subj":"T101","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A102","pred":"fma_id","subj":"T102","obj":"http://purl.org/sig/ont/fma/fma62970"},{"id":"A103","pred":"fma_id","subj":"T103","obj":"http://purl.org/sig/ont/fma/fma84050"}],"text":"Some clinical studies have found that high concentrations of cytokines and pro-inflammatory factors such as IL-6 and IL-10 are elevated in the plasma of critically ill patients infected with SARS-CoV-2 [46,47], suggesting that cytokine release syndrome (CRS) is associated with disease severity."}
LitCovid-sample-PD-MONDO
{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T80","span":{"begin":191,"end":201},"obj":"Disease"},{"id":"T81","span":{"begin":254,"end":257},"obj":"Disease"}],"attributes":[{"id":"A80","pred":"mondo_id","subj":"T80","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A81","pred":"mondo_id","subj":"T81","obj":"http://purl.obolibrary.org/obo/MONDO_0007399"},{"id":"A82","pred":"mondo_id","subj":"T81","obj":"http://purl.obolibrary.org/obo/MONDO_0017361"}],"text":"Some clinical studies have found that high concentrations of cytokines and pro-inflammatory factors such as IL-6 and IL-10 are elevated in the plasma of critically ill patients infected with SARS-CoV-2 [46,47], suggesting that cytokine release syndrome (CRS) is associated with disease severity."}
LitCovid-PubTator
{"project":"LitCovid-PubTator","denotations":[{"id":"531","span":{"begin":108,"end":112},"obj":"Gene"},{"id":"532","span":{"begin":117,"end":122},"obj":"Gene"},{"id":"533","span":{"begin":168,"end":176},"obj":"Species"},{"id":"534","span":{"begin":191,"end":201},"obj":"Species"},{"id":"545","span":{"begin":153,"end":167},"obj":"Disease"},{"id":"546","span":{"begin":177,"end":185},"obj":"Disease"},{"id":"547","span":{"begin":254,"end":257},"obj":"Disease"}],"attributes":[{"id":"A531","pred":"tao:has_database_id","subj":"531","obj":"Gene:3569"},{"id":"A532","pred":"tao:has_database_id","subj":"532","obj":"Gene:3586"},{"id":"A533","pred":"tao:has_database_id","subj":"533","obj":"Tax:9606"},{"id":"A534","pred":"tao:has_database_id","subj":"534","obj":"Tax:2697049"},{"id":"A545","pred":"tao:has_database_id","subj":"545","obj":"MESH:D016638"},{"id":"A546","pred":"tao:has_database_id","subj":"546","obj":"MESH:D007239"},{"id":"A547","pred":"tao:has_database_id","subj":"547","obj":"MESH:D003398"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Some clinical studies have found that high concentrations of cytokines and pro-inflammatory factors such as IL-6 and IL-10 are elevated in the plasma of critically ill patients infected with SARS-CoV-2 [46,47], suggesting that cytokine release syndrome (CRS) is associated with disease severity."}
LitCovid-sentences
{"project":"LitCovid-sentences","denotations":[{"id":"T102","span":{"begin":0,"end":295},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Some clinical studies have found that high concentrations of cytokines and pro-inflammatory factors such as IL-6 and IL-10 are elevated in the plasma of critically ill patients infected with SARS-CoV-2 [46,47], suggesting that cytokine release syndrome (CRS) is associated with disease severity."}
LitCovid-PD-HP
{"project":"LitCovid-PD-HP","denotations":[{"id":"T11","span":{"begin":227,"end":252},"obj":"Phenotype"}],"attributes":[{"id":"A11","pred":"hp_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/HP_0033041"}],"text":"Some clinical studies have found that high concentrations of cytokines and pro-inflammatory factors such as IL-6 and IL-10 are elevated in the plasma of critically ill patients infected with SARS-CoV-2 [46,47], suggesting that cytokine release syndrome (CRS) is associated with disease severity."}
2_test
{"project":"2_test","denotations":[{"id":"32496926-31986264-132195699","span":{"begin":203,"end":205},"obj":"31986264"},{"id":"32496926-32007143-132195700","span":{"begin":206,"end":208},"obj":"32007143"}],"text":"Some clinical studies have found that high concentrations of cytokines and pro-inflammatory factors such as IL-6 and IL-10 are elevated in the plasma of critically ill patients infected with SARS-CoV-2 [46,47], suggesting that cytokine release syndrome (CRS) is associated with disease severity."}