PMC:7441788 / 1118-1749 JSONTXT

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T13","span":{"begin":162,"end":170},"obj":"Disease"},{"id":"T14","span":{"begin":257,"end":265},"obj":"Disease"},{"id":"T15","span":{"begin":372,"end":380},"obj":"Disease"},{"id":"T16","span":{"begin":455,"end":463},"obj":"Disease"},{"id":"T17","span":{"begin":610,"end":618},"obj":"Disease"}],"attributes":[{"id":"A13","pred":"mondo_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A14","pred":"mondo_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A15","pred":"mondo_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A16","pred":"mondo_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A17","pred":"mondo_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"e effects. However, recent studies indicated that the use of CQ/HCQ, alone or in combination with a macrolide, did not show any favorable effect on patients with COVID-19. Adverse effects, including prolonged QT interval after taking CQ/HCQ, may develop in COVID-19 patients. Therefore, current data are not sufficient enough to support the use of CQ/HCQ as therapies for COVID-19 and increasing caution should be taken about the application of CQ/HCQ in COVID-19 before conclusive findings are obtained by well-designed, multi-center, randomized, controlled studies.\n\n1. Introduction\nCoronavirus disease-19 (COVID-19) caused by s"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T6","span":{"begin":98,"end":99},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"e effects. However, recent studies indicated that the use of CQ/HCQ, alone or in combination with a macrolide, did not show any favorable effect on patients with COVID-19. Adverse effects, including prolonged QT interval after taking CQ/HCQ, may develop in COVID-19 patients. Therefore, current data are not sufficient enough to support the use of CQ/HCQ as therapies for COVID-19 and increasing caution should be taken about the application of CQ/HCQ in COVID-19 before conclusive findings are obtained by well-designed, multi-center, randomized, controlled studies.\n\n1. Introduction\nCoronavirus disease-19 (COVID-19) caused by s"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T13","span":{"begin":61,"end":63},"obj":"Chemical"},{"id":"T14","span":{"begin":100,"end":109},"obj":"Chemical"},{"id":"T15","span":{"begin":234,"end":236},"obj":"Chemical"},{"id":"T16","span":{"begin":348,"end":350},"obj":"Chemical"},{"id":"T17","span":{"begin":430,"end":441},"obj":"Chemical"},{"id":"T18","span":{"begin":445,"end":447},"obj":"Chemical"}],"attributes":[{"id":"A13","pred":"chebi_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"id":"A14","pred":"chebi_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_25106"},{"id":"A15","pred":"chebi_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"id":"A16","pred":"chebi_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"id":"A17","pred":"chebi_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_33232"},{"id":"A18","pred":"chebi_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"}],"text":"e effects. However, recent studies indicated that the use of CQ/HCQ, alone or in combination with a macrolide, did not show any favorable effect on patients with COVID-19. Adverse effects, including prolonged QT interval after taking CQ/HCQ, may develop in COVID-19 patients. Therefore, current data are not sufficient enough to support the use of CQ/HCQ as therapies for COVID-19 and increasing caution should be taken about the application of CQ/HCQ in COVID-19 before conclusive findings are obtained by well-designed, multi-center, randomized, controlled studies.\n\n1. Introduction\nCoronavirus disease-19 (COVID-19) caused by s"}

{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T10","span":{"begin":61,"end":63},"obj":"Chemical"},{"id":"T11","span":{"begin":100,"end":109},"obj":"Chemical"},{"id":"T12","span":{"begin":234,"end":236},"obj":"Chemical"},{"id":"T13","span":{"begin":348,"end":350},"obj":"Chemical"},{"id":"T14","span":{"begin":445,"end":447},"obj":"Chemical"}],"attributes":[{"id":"A10","pred":"chebi_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"id":"A11","pred":"chebi_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_25106"},{"id":"A12","pred":"chebi_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"id":"A13","pred":"chebi_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"id":"A14","pred":"chebi_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"}],"text":"e effects. However, recent studies indicated that the use of CQ/HCQ, alone or in combination with a macrolide, did not show any favorable effect on patients with COVID-19. Adverse effects, including prolonged QT interval after taking CQ/HCQ, may develop in COVID-19 patients. Therefore, current data are not sufficient enough to support the use of CQ/HCQ as therapies for COVID-19 and increasing caution should be taken about the application of CQ/HCQ in COVID-19 before conclusive findings are obtained by well-designed, multi-center, randomized, controlled studies.\n\n1. Introduction\nCoronavirus disease-19 (COVID-19) caused by s"}

{"project":"LitCovid-sample-PD-NCBITaxon","denotations":[{"id":"T11","span":{"begin":162,"end":170},"obj":"Species"},{"id":"T12","span":{"begin":257,"end":265},"obj":"Species"},{"id":"T13","span":{"begin":372,"end":380},"obj":"Species"},{"id":"T14","span":{"begin":455,"end":463},"obj":"Species"},{"id":"T15","span":{"begin":610,"end":618},"obj":"Species"}],"attributes":[{"id":"A11","pred":"ncbi_taxonomy_id","subj":"T11","obj":"NCBItxid:2697049"},{"id":"A12","pred":"ncbi_taxonomy_id","subj":"T12","obj":"NCBItxid:2697049"},{"id":"A13","pred":"ncbi_taxonomy_id","subj":"T13","obj":"NCBItxid:2697049"},{"id":"A14","pred":"ncbi_taxonomy_id","subj":"T14","obj":"NCBItxid:2697049"},{"id":"A15","pred":"ncbi_taxonomy_id","subj":"T15","obj":"NCBItxid:2697049"}],"namespaces":[{"prefix":"NCBItxid","uri":"http://purl.bioontology.org/ontology/NCBITAXON/"}],"text":"e effects. However, recent studies indicated that the use of CQ/HCQ, alone or in combination with a macrolide, did not show any favorable effect on patients with COVID-19. Adverse effects, including prolonged QT interval after taking CQ/HCQ, may develop in COVID-19 patients. Therefore, current data are not sufficient enough to support the use of CQ/HCQ as therapies for COVID-19 and increasing caution should be taken about the application of CQ/HCQ in COVID-19 before conclusive findings are obtained by well-designed, multi-center, randomized, controlled studies.\n\n1. Introduction\nCoronavirus disease-19 (COVID-19) caused by s"}

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T14","span":{"begin":11,"end":171},"obj":"Sentence"},{"id":"T15","span":{"begin":172,"end":275},"obj":"Sentence"},{"id":"T16","span":{"begin":276,"end":567},"obj":"Sentence"},{"id":"T17","span":{"begin":569,"end":571},"obj":"Sentence"},{"id":"T18","span":{"begin":573,"end":585},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"e effects. However, recent studies indicated that the use of CQ/HCQ, alone or in combination with a macrolide, did not show any favorable effect on patients with COVID-19. Adverse effects, including prolonged QT interval after taking CQ/HCQ, may develop in COVID-19 patients. Therefore, current data are not sufficient enough to support the use of CQ/HCQ as therapies for COVID-19 and increasing caution should be taken about the application of CQ/HCQ in COVID-19 before conclusive findings are obtained by well-designed, multi-center, randomized, controlled studies.\n\n1. Introduction\nCoronavirus disease-19 (COVID-19) caused by s"}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"120","span":{"begin":610,"end":618},"obj":"Disease"},{"id":"46","span":{"begin":148,"end":156},"obj":"Species"},{"id":"47","span":{"begin":266,"end":274},"obj":"Species"},{"id":"55","span":{"begin":61,"end":67},"obj":"Chemical"},{"id":"56","span":{"begin":100,"end":109},"obj":"Chemical"},{"id":"57","span":{"begin":234,"end":236},"obj":"Chemical"},{"id":"58","span":{"begin":237,"end":240},"obj":"Chemical"},{"id":"59","span":{"begin":348,"end":350},"obj":"Chemical"},{"id":"60","span":{"begin":351,"end":354},"obj":"Chemical"},{"id":"61","span":{"begin":445,"end":447},"obj":"Chemical"},{"id":"62","span":{"begin":448,"end":451},"obj":"Chemical"},{"id":"70","span":{"begin":162,"end":170},"obj":"Disease"},{"id":"71","span":{"begin":257,"end":265},"obj":"Disease"},{"id":"72","span":{"begin":372,"end":380},"obj":"Disease"},{"id":"73","span":{"begin":455,"end":463},"obj":"Disease"}],"attributes":[{"id":"A72","pred":"pubann:denotes","subj":"72","obj":"MESH:C000657245"},{"id":"A73","pred":"pubann:denotes","subj":"73","obj":"MESH:C000657245"},{"id":"A61","pred":"pubann:denotes","subj":"61","obj":"MESH:D002738"},{"id":"A57","pred":"pubann:denotes","subj":"57","obj":"MESH:D002738"},{"id":"A62","pred":"pubann:denotes","subj":"62","obj":"MESH:D006886"},{"id":"A60","pred":"pubann:denotes","subj":"60","obj":"MESH:D006886"},{"id":"A120","pred":"pubann:denotes","subj":"120","obj":"MESH:C000657245"},{"id":"A70","pred":"pubann:denotes","subj":"70","obj":"MESH:C000657245"},{"id":"A46","pred":"pubann:denotes","subj":"46","obj":"Tax:9606"},{"id":"A71","pred":"pubann:denotes","subj":"71","obj":"MESH:C000657245"},{"id":"A58","pred":"pubann:denotes","subj":"58","obj":"MESH:D006886"},{"id":"A47","pred":"pubann:denotes","subj":"47","obj":"Tax:9606"},{"id":"A59","pred":"pubann:denotes","subj":"59","obj":"MESH:D002738"},{"id":"A56","pred":"pubann:denotes","subj":"56","obj":"MESH:D018942"}],"text":"e effects. However, recent studies indicated that the use of CQ/HCQ, alone or in combination with a macrolide, did not show any favorable effect on patients with COVID-19. Adverse effects, including prolonged QT interval after taking CQ/HCQ, may develop in COVID-19 patients. Therefore, current data are not sufficient enough to support the use of CQ/HCQ as therapies for COVID-19 and increasing caution should be taken about the application of CQ/HCQ in COVID-19 before conclusive findings are obtained by well-designed, multi-center, randomized, controlled studies.\n\n1. Introduction\nCoronavirus disease-19 (COVID-19) caused by s"}

{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T5","span":{"begin":598,"end":605},"obj":"http://purl.obolibrary.org/obo/OGMS_0000031"}],"text":"e effects. However, recent studies indicated that the use of CQ/HCQ, alone or in combination with a macrolide, did not show any favorable effect on patients with COVID-19. Adverse effects, including prolonged QT interval after taking CQ/HCQ, may develop in COVID-19 patients. Therefore, current data are not sufficient enough to support the use of CQ/HCQ as therapies for COVID-19 and increasing caution should be taken about the application of CQ/HCQ in COVID-19 before conclusive findings are obtained by well-designed, multi-center, randomized, controlled studies.\n\n1. Introduction\nCoronavirus disease-19 (COVID-19) caused by s"}

{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T11","span":{"begin":162,"end":170},"obj":"Disease"},{"id":"T12","span":{"begin":257,"end":265},"obj":"Disease"},{"id":"T13","span":{"begin":372,"end":380},"obj":"Disease"},{"id":"T14","span":{"begin":455,"end":463},"obj":"Disease"},{"id":"T15","span":{"begin":586,"end":608},"obj":"Disease"},{"id":"T16","span":{"begin":610,"end":618},"obj":"Disease"}],"attributes":[{"id":"A11","pred":"mondo_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A12","pred":"mondo_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A13","pred":"mondo_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A14","pred":"mondo_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A15","pred":"mondo_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A16","pred":"mondo_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"e effects. However, recent studies indicated that the use of CQ/HCQ, alone or in combination with a macrolide, did not show any favorable effect on patients with COVID-19. Adverse effects, including prolonged QT interval after taking CQ/HCQ, may develop in COVID-19 patients. Therefore, current data are not sufficient enough to support the use of CQ/HCQ as therapies for COVID-19 and increasing caution should be taken about the application of CQ/HCQ in COVID-19 before conclusive findings are obtained by well-designed, multi-center, randomized, controlled studies.\n\n1. Introduction\nCoronavirus disease-19 (COVID-19) caused by s"}

{"project":"LitCovid-sample-PD-HP","denotations":[{"id":"T1","span":{"begin":199,"end":220},"obj":"Phenotype"}],"attributes":[{"id":"A1","pred":"hp_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/HP_0001657"}],"text":"e effects. However, recent studies indicated that the use of CQ/HCQ, alone or in combination with a macrolide, did not show any favorable effect on patients with COVID-19. Adverse effects, including prolonged QT interval after taking CQ/HCQ, may develop in COVID-19 patients. Therefore, current data are not sufficient enough to support the use of CQ/HCQ as therapies for COVID-19 and increasing caution should be taken about the application of CQ/HCQ in COVID-19 before conclusive findings are obtained by well-designed, multi-center, randomized, controlled studies.\n\n1. Introduction\nCoronavirus disease-19 (COVID-19) caused by s"}

{"project":"LitCovid-PubTator","denotations":[{"id":"46","span":{"begin":148,"end":156},"obj":"Species"},{"id":"47","span":{"begin":266,"end":274},"obj":"Species"},{"id":"55","span":{"begin":61,"end":67},"obj":"Chemical"},{"id":"56","span":{"begin":100,"end":109},"obj":"Chemical"},{"id":"57","span":{"begin":234,"end":236},"obj":"Chemical"},{"id":"58","span":{"begin":237,"end":240},"obj":"Chemical"},{"id":"59","span":{"begin":348,"end":350},"obj":"Chemical"},{"id":"60","span":{"begin":351,"end":354},"obj":"Chemical"},{"id":"61","span":{"begin":445,"end":447},"obj":"Chemical"},{"id":"62","span":{"begin":448,"end":451},"obj":"Chemical"},{"id":"70","span":{"begin":162,"end":170},"obj":"Disease"},{"id":"71","span":{"begin":257,"end":265},"obj":"Disease"},{"id":"72","span":{"begin":372,"end":380},"obj":"Disease"},{"id":"73","span":{"begin":455,"end":463},"obj":"Disease"},{"id":"119","span":{"begin":586,"end":608},"obj":"Disease"},{"id":"120","span":{"begin":610,"end":618},"obj":"Disease"}],"attributes":[{"id":"A46","pred":"tao:has_database_id","subj":"46","obj":"Tax:9606"},{"id":"A47","pred":"tao:has_database_id","subj":"47","obj":"Tax:9606"},{"id":"A56","pred":"tao:has_database_id","subj":"56","obj":"MESH:D018942"},{"id":"A57","pred":"tao:has_database_id","subj":"57","obj":"MESH:D002738"},{"id":"A58","pred":"tao:has_database_id","subj":"58","obj":"MESH:D006886"},{"id":"A59","pred":"tao:has_database_id","subj":"59","obj":"MESH:D002738"},{"id":"A60","pred":"tao:has_database_id","subj":"60","obj":"MESH:D006886"},{"id":"A61","pred":"tao:has_database_id","subj":"61","obj":"MESH:D002738"},{"id":"A62","pred":"tao:has_database_id","subj":"62","obj":"MESH:D006886"},{"id":"A70","pred":"tao:has_database_id","subj":"70","obj":"MESH:C000657245"},{"id":"A71","pred":"tao:has_database_id","subj":"71","obj":"MESH:C000657245"},{"id":"A72","pred":"tao:has_database_id","subj":"72","obj":"MESH:C000657245"},{"id":"A73","pred":"tao:has_database_id","subj":"73","obj":"MESH:C000657245"},{"id":"A119","pred":"tao:has_database_id","subj":"119","obj":"MESH:C000657245"},{"id":"A120","pred":"tao:has_database_id","subj":"120","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"e effects. However, recent studies indicated that the use of CQ/HCQ, alone or in combination with a macrolide, did not show any favorable effect on patients with COVID-19. Adverse effects, including prolonged QT interval after taking CQ/HCQ, may develop in COVID-19 patients. Therefore, current data are not sufficient enough to support the use of CQ/HCQ as therapies for COVID-19 and increasing caution should be taken about the application of CQ/HCQ in COVID-19 before conclusive findings are obtained by well-designed, multi-center, randomized, controlled studies.\n\n1. Introduction\nCoronavirus disease-19 (COVID-19) caused by s"}

{"project":"LitCovid-sentences","denotations":[{"id":"T14","span":{"begin":11,"end":171},"obj":"Sentence"},{"id":"T15","span":{"begin":172,"end":275},"obj":"Sentence"},{"id":"T16","span":{"begin":276,"end":567},"obj":"Sentence"},{"id":"T17","span":{"begin":569,"end":571},"obj":"Sentence"},{"id":"T18","span":{"begin":573,"end":585},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"e effects. However, recent studies indicated that the use of CQ/HCQ, alone or in combination with a macrolide, did not show any favorable effect on patients with COVID-19. Adverse effects, including prolonged QT interval after taking CQ/HCQ, may develop in COVID-19 patients. Therefore, current data are not sufficient enough to support the use of CQ/HCQ as therapies for COVID-19 and increasing caution should be taken about the application of CQ/HCQ in COVID-19 before conclusive findings are obtained by well-designed, multi-center, randomized, controlled studies.\n\n1. Introduction\nCoronavirus disease-19 (COVID-19) caused by s"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T1","span":{"begin":199,"end":220},"obj":"Phenotype"}],"attributes":[{"id":"A1","pred":"hp_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/HP_0001657"}],"text":"e effects. However, recent studies indicated that the use of CQ/HCQ, alone or in combination with a macrolide, did not show any favorable effect on patients with COVID-19. Adverse effects, including prolonged QT interval after taking CQ/HCQ, may develop in COVID-19 patients. Therefore, current data are not sufficient enough to support the use of CQ/HCQ as therapies for COVID-19 and increasing caution should be taken about the application of CQ/HCQ in COVID-19 before conclusive findings are obtained by well-designed, multi-center, randomized, controlled studies.\n\n1. Introduction\nCoronavirus disease-19 (COVID-19) caused by s"}