PMC:7441788 / 0-631 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T1","span":{"begin":382,"end":391},"obj":"Body_part"},{"id":"T2","span":{"begin":564,"end":572},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma46831"},{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma67180"}],"text":"Advances in the use of chloroquine and hydroxychloroquine for the treatment of COVID-19\nJ. SUN ET AL.\nPOSTGRADUATE MEDICINE\n\nAbstract\nABSTRACT\nCoronavirus Disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading worldwide. Antiviral therapy is the most important treatment for COVID-19. Among the drugs under investigation, anti-malarials, chloroquine (CQ) and hydroxychloroquine (HCQ), are being repurposed as treatment for COVID-19. CQ/HCQ were shown to prevent receptor recognition by coronaviruses, inhibit endosome acidification, which interferes with membrane fusion, and "}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T1","span":{"begin":79,"end":87},"obj":"Disease"},{"id":"T2","span":{"begin":95,"end":97},"obj":"Disease"},{"id":"T3","span":{"begin":143,"end":167},"obj":"Disease"},{"id":"T4","span":{"begin":169,"end":177},"obj":"Disease"},{"id":"T5","span":{"begin":190,"end":237},"obj":"Disease"},{"id":"T6","span":{"begin":190,"end":223},"obj":"Disease"},{"id":"T7","span":{"begin":239,"end":247},"obj":"Disease"},{"id":"T8","span":{"begin":330,"end":338},"obj":"Disease"},{"id":"T9","span":{"begin":478,"end":486},"obj":"Disease"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/MONDO_0005029"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A6","pred":"mondo_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A7","pred":"mondo_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A8","pred":"mondo_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A9","pred":"mondo_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"Advances in the use of chloroquine and hydroxychloroquine for the treatment of COVID-19\nJ. SUN ET AL.\nPOSTGRADUATE MEDICINE\n\nAbstract\nABSTRACT\nCoronavirus Disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading worldwide. Antiviral therapy is the most important treatment for COVID-19. Among the drugs under investigation, anti-malarials, chloroquine (CQ) and hydroxychloroquine (HCQ), are being repurposed as treatment for COVID-19. CQ/HCQ were shown to prevent receptor recognition by coronaviruses, inhibit endosome acidification, which interferes with membrane fusion, and "}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T1","span":{"begin":610,"end":618},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"}],"text":"Advances in the use of chloroquine and hydroxychloroquine for the treatment of COVID-19\nJ. SUN ET AL.\nPOSTGRADUATE MEDICINE\n\nAbstract\nABSTRACT\nCoronavirus Disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading worldwide. Antiviral therapy is the most important treatment for COVID-19. Among the drugs under investigation, anti-malarials, chloroquine (CQ) and hydroxychloroquine (HCQ), are being repurposed as treatment for COVID-19. CQ/HCQ were shown to prevent receptor recognition by coronaviruses, inhibit endosome acidification, which interferes with membrane fusion, and "}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T1","span":{"begin":23,"end":34},"obj":"Chemical"},{"id":"T2","span":{"begin":39,"end":57},"obj":"Chemical"},{"id":"T3","span":{"begin":95,"end":97},"obj":"Chemical"},{"id":"T4","span":{"begin":98,"end":100},"obj":"Chemical"},{"id":"T5","span":{"begin":350,"end":355},"obj":"Chemical"},{"id":"T6","span":{"begin":393,"end":404},"obj":"Chemical"},{"id":"T7","span":{"begin":406,"end":408},"obj":"Chemical"},{"id":"T8","span":{"begin":414,"end":432},"obj":"Chemical"},{"id":"T9","span":{"begin":488,"end":490},"obj":"Chemical"}],"attributes":[{"id":"A1","pred":"chebi_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"id":"A2","pred":"chebi_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/CHEBI_5801"},{"id":"A3","pred":"chebi_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/CHEBI_73510"},{"id":"A4","pred":"chebi_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_73770"},{"id":"A5","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A6","pred":"chebi_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"id":"A7","pred":"chebi_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"id":"A8","pred":"chebi_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/CHEBI_5801"},{"id":"A9","pred":"chebi_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"}],"text":"Advances in the use of chloroquine and hydroxychloroquine for the treatment of COVID-19\nJ. SUN ET AL.\nPOSTGRADUATE MEDICINE\n\nAbstract\nABSTRACT\nCoronavirus Disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading worldwide. Antiviral therapy is the most important treatment for COVID-19. Among the drugs under investigation, anti-malarials, chloroquine (CQ) and hydroxychloroquine (HCQ), are being repurposed as treatment for COVID-19. CQ/HCQ were shown to prevent receptor recognition by coronaviruses, inhibit endosome acidification, which interferes with membrane fusion, and "}

{"project":"LitCovid-sample-MedDRA","denotations":[{"id":"T1","span":{"begin":362,"end":375},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"}],"attributes":[{"id":"A1","pred":"meddra_id","subj":"T1","obj":"http://purl.bioontology.org/ontology/MEDDRA/10062026"}],"text":"Advances in the use of chloroquine and hydroxychloroquine for the treatment of COVID-19\nJ. SUN ET AL.\nPOSTGRADUATE MEDICINE\n\nAbstract\nABSTRACT\nCoronavirus Disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading worldwide. Antiviral therapy is the most important treatment for COVID-19. Among the drugs under investigation, anti-malarials, chloroquine (CQ) and hydroxychloroquine (HCQ), are being repurposed as treatment for COVID-19. CQ/HCQ were shown to prevent receptor recognition by coronaviruses, inhibit endosome acidification, which interferes with membrane fusion, and "}

{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T1","span":{"begin":23,"end":34},"obj":"Chemical"},{"id":"T2","span":{"begin":39,"end":57},"obj":"Chemical"},{"id":"T3","span":{"begin":393,"end":404},"obj":"Chemical"},{"id":"T4","span":{"begin":406,"end":408},"obj":"Chemical"},{"id":"T5","span":{"begin":414,"end":432},"obj":"Chemical"},{"id":"T6","span":{"begin":488,"end":490},"obj":"Chemical"}],"attributes":[{"id":"A1","pred":"chebi_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"id":"A2","pred":"chebi_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/CHEBI_5801"},{"id":"A3","pred":"chebi_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"id":"A4","pred":"chebi_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"id":"A5","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_5801"},{"id":"A6","pred":"chebi_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"}],"text":"Advances in the use of chloroquine and hydroxychloroquine for the treatment of COVID-19\nJ. SUN ET AL.\nPOSTGRADUATE MEDICINE\n\nAbstract\nABSTRACT\nCoronavirus Disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading worldwide. Antiviral therapy is the most important treatment for COVID-19. Among the drugs under investigation, anti-malarials, chloroquine (CQ) and hydroxychloroquine (HCQ), are being repurposed as treatment for COVID-19. CQ/HCQ were shown to prevent receptor recognition by coronaviruses, inhibit endosome acidification, which interferes with membrane fusion, and "}

{"project":"LitCovid-sample-PD-NCBITaxon","denotations":[{"id":"T1","span":{"begin":79,"end":87},"obj":"Species"},{"id":"T2","span":{"begin":143,"end":167},"obj":"Species"},{"id":"T3","span":{"begin":169,"end":177},"obj":"Species"},{"id":"T4","span":{"begin":190,"end":237},"obj":"Species"},{"id":"T5","span":{"begin":239,"end":249},"obj":"Species"},{"id":"T6","span":{"begin":330,"end":338},"obj":"Species"},{"id":"T7","span":{"begin":478,"end":486},"obj":"Species"}],"attributes":[{"id":"A1","pred":"ncbi_taxonomy_id","subj":"T1","obj":"NCBItxid:2697049"},{"id":"A2","pred":"ncbi_taxonomy_id","subj":"T2","obj":"NCBItxid:2697049"},{"id":"A3","pred":"ncbi_taxonomy_id","subj":"T3","obj":"NCBItxid:2697049"},{"id":"A4","pred":"ncbi_taxonomy_id","subj":"T4","obj":"NCBItxid:2697049"},{"id":"A5","pred":"ncbi_taxonomy_id","subj":"T5","obj":"NCBItxid:2697049"},{"id":"A6","pred":"ncbi_taxonomy_id","subj":"T6","obj":"NCBItxid:2697049"},{"id":"A7","pred":"ncbi_taxonomy_id","subj":"T7","obj":"NCBItxid:2697049"}],"namespaces":[{"prefix":"NCBItxid","uri":"http://purl.bioontology.org/ontology/NCBITAXON/"}],"text":"Advances in the use of chloroquine and hydroxychloroquine for the treatment of COVID-19\nJ. SUN ET AL.\nPOSTGRADUATE MEDICINE\n\nAbstract\nABSTRACT\nCoronavirus Disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading worldwide. Antiviral therapy is the most important treatment for COVID-19. Among the drugs under investigation, anti-malarials, chloroquine (CQ) and hydroxychloroquine (HCQ), are being repurposed as treatment for COVID-19. CQ/HCQ were shown to prevent receptor recognition by coronaviruses, inhibit endosome acidification, which interferes with membrane fusion, and "}

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T1","span":{"begin":0,"end":87},"obj":"Sentence"},{"id":"T2","span":{"begin":88,"end":90},"obj":"Sentence"},{"id":"T3","span":{"begin":91,"end":101},"obj":"Sentence"},{"id":"T4","span":{"begin":102,"end":123},"obj":"Sentence"},{"id":"T5","span":{"begin":125,"end":133},"obj":"Sentence"},{"id":"T6","span":{"begin":134,"end":142},"obj":"Sentence"},{"id":"T7","span":{"begin":143,"end":275},"obj":"Sentence"},{"id":"T8","span":{"begin":276,"end":339},"obj":"Sentence"},{"id":"T9","span":{"begin":340,"end":487},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Advances in the use of chloroquine and hydroxychloroquine for the treatment of COVID-19\nJ. SUN ET AL.\nPOSTGRADUATE MEDICINE\n\nAbstract\nABSTRACT\nCoronavirus Disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading worldwide. Antiviral therapy is the most important treatment for COVID-19. Among the drugs under investigation, anti-malarials, chloroquine (CQ) and hydroxychloroquine (HCQ), are being repurposed as treatment for COVID-19. CQ/HCQ were shown to prevent receptor recognition by coronaviruses, inhibit endosome acidification, which interferes with membrane fusion, and "}

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{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T1","span":{"begin":155,"end":162},"obj":"http://purl.obolibrary.org/obo/OGMS_0000031"},{"id":"T2","span":{"begin":276,"end":285},"obj":"http://purl.obolibrary.org/obo/IDO_0000559"}],"text":"Advances in the use of chloroquine and hydroxychloroquine for the treatment of COVID-19\nJ. SUN ET AL.\nPOSTGRADUATE MEDICINE\n\nAbstract\nABSTRACT\nCoronavirus Disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading worldwide. Antiviral therapy is the most important treatment for COVID-19. Among the drugs under investigation, anti-malarials, chloroquine (CQ) and hydroxychloroquine (HCQ), are being repurposed as treatment for COVID-19. CQ/HCQ were shown to prevent receptor recognition by coronaviruses, inhibit endosome acidification, which interferes with membrane fusion, and "}

{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T1","span":{"begin":382,"end":391},"obj":"Body_part"},{"id":"T2","span":{"begin":564,"end":572},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma46831"},{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma67180"}],"text":"Advances in the use of chloroquine and hydroxychloroquine for the treatment of COVID-19\nJ. SUN ET AL.\nPOSTGRADUATE MEDICINE\n\nAbstract\nABSTRACT\nCoronavirus Disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading worldwide. Antiviral therapy is the most important treatment for COVID-19. Among the drugs under investigation, anti-malarials, chloroquine (CQ) and hydroxychloroquine (HCQ), are being repurposed as treatment for COVID-19. CQ/HCQ were shown to prevent receptor recognition by coronaviruses, inhibit endosome acidification, which interferes with membrane fusion, and "}

{"project":"LitCovid-sample-PD-GO-BP-0","denotations":[{"id":"T1","span":{"begin":573,"end":586},"obj":"http://purl.obolibrary.org/obo/GO_0045851"},{"id":"T2","span":{"begin":610,"end":625},"obj":"http://purl.obolibrary.org/obo/GO_0061025"}],"text":"Advances in the use of chloroquine and hydroxychloroquine for the treatment of COVID-19\nJ. SUN ET AL.\nPOSTGRADUATE MEDICINE\n\nAbstract\nABSTRACT\nCoronavirus Disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading worldwide. Antiviral therapy is the most important treatment for COVID-19. Among the drugs under investigation, anti-malarials, chloroquine (CQ) and hydroxychloroquine (HCQ), are being repurposed as treatment for COVID-19. CQ/HCQ were shown to prevent receptor recognition by coronaviruses, inhibit endosome acidification, which interferes with membrane fusion, and "}

{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T1","span":{"begin":79,"end":87},"obj":"Disease"},{"id":"T2","span":{"begin":143,"end":167},"obj":"Disease"},{"id":"T3","span":{"begin":169,"end":177},"obj":"Disease"},{"id":"T4","span":{"begin":190,"end":237},"obj":"Disease"},{"id":"T5","span":{"begin":239,"end":249},"obj":"Disease"},{"id":"T6","span":{"begin":330,"end":338},"obj":"Disease"},{"id":"T7","span":{"begin":478,"end":486},"obj":"Disease"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A6","pred":"mondo_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A7","pred":"mondo_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"Advances in the use of chloroquine and hydroxychloroquine for the treatment of COVID-19\nJ. SUN ET AL.\nPOSTGRADUATE MEDICINE\n\nAbstract\nABSTRACT\nCoronavirus Disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading worldwide. Antiviral therapy is the most important treatment for COVID-19. Among the drugs under investigation, anti-malarials, chloroquine (CQ) and hydroxychloroquine (HCQ), are being repurposed as treatment for COVID-19. CQ/HCQ were shown to prevent receptor recognition by coronaviruses, inhibit endosome acidification, which interferes with membrane fusion, and "}

{"project":"LitCovid-sample-GO-BP","denotations":[{"id":"T1","span":{"begin":573,"end":586},"obj":"http://purl.obolibrary.org/obo/GO_0045851"},{"id":"T2","span":{"begin":610,"end":625},"obj":"http://purl.obolibrary.org/obo/GO_0061025"}],"text":"Advances in the use of chloroquine and hydroxychloroquine for the treatment of COVID-19\nJ. SUN ET AL.\nPOSTGRADUATE MEDICINE\n\nAbstract\nABSTRACT\nCoronavirus Disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading worldwide. Antiviral therapy is the most important treatment for COVID-19. Among the drugs under investigation, anti-malarials, chloroquine (CQ) and hydroxychloroquine (HCQ), are being repurposed as treatment for COVID-19. CQ/HCQ were shown to prevent receptor recognition by coronaviruses, inhibit endosome acidification, which interferes with membrane fusion, and "}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T1","span":{"begin":573,"end":586},"obj":"http://purl.obolibrary.org/obo/GO_0045851"},{"id":"T2","span":{"begin":610,"end":625},"obj":"http://purl.obolibrary.org/obo/GO_0061025"}],"text":"Advances in the use of chloroquine and hydroxychloroquine for the treatment of COVID-19\nJ. SUN ET AL.\nPOSTGRADUATE MEDICINE\n\nAbstract\nABSTRACT\nCoronavirus Disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading worldwide. Antiviral therapy is the most important treatment for COVID-19. Among the drugs under investigation, anti-malarials, chloroquine (CQ) and hydroxychloroquine (HCQ), are being repurposed as treatment for COVID-19. CQ/HCQ were shown to prevent receptor recognition by coronaviruses, inhibit endosome acidification, which interferes with membrane fusion, and "}

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