PMC:7441777 / 44179-44661 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T86","span":{"begin":271,"end":275},"obj":"Body_part"},{"id":"T87","span":{"begin":296,"end":301},"obj":"Body_part"},{"id":"T88","span":{"begin":330,"end":336},"obj":"Body_part"},{"id":"T89","span":{"begin":360,"end":364},"obj":"Body_part"},{"id":"T90","span":{"begin":384,"end":389},"obj":"Body_part"}],"attributes":[{"id":"A86","pred":"fma_id","subj":"T86","obj":"http://purl.org/sig/ont/fma/fma62971"},{"id":"A87","pred":"fma_id","subj":"T87","obj":"http://purl.org/sig/ont/fma/fma12275"},{"id":"A88","pred":"fma_id","subj":"T88","obj":"http://purl.org/sig/ont/fma/fma62970"},{"id":"A89","pred":"fma_id","subj":"T89","obj":"http://purl.org/sig/ont/fma/fma62971"},{"id":"A90","pred":"fma_id","subj":"T90","obj":"http://purl.org/sig/ont/fma/fma14543"}],"text":"Among the five compounds, TF2b and TF3 were predicted as the substrate of renal organic cation transporter-2 (Renal OCT2), as shown in Table S6 in the Supplementary Information. While EGCG, TF2a, and remdesivir are possibly cleared through other available routes such as bile, breath, faces, and sweat. EGCG remains intact in the plasma and later excreted via bile and metabolized by colon microflora. It is also expected that all the compounds are absorbable via oral prescription."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T23","span":{"begin":271,"end":275},"obj":"Body_part"},{"id":"T24","span":{"begin":296,"end":301},"obj":"Body_part"},{"id":"T25","span":{"begin":360,"end":364},"obj":"Body_part"},{"id":"T26","span":{"begin":384,"end":389},"obj":"Body_part"}],"attributes":[{"id":"A23","pred":"uberon_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/UBERON_0001970"},{"id":"A24","pred":"uberon_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/UBERON_0001089"},{"id":"A25","pred":"uberon_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/UBERON_0001970"},{"id":"A26","pred":"uberon_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/UBERON_0001155"}],"text":"Among the five compounds, TF2b and TF3 were predicted as the substrate of renal organic cation transporter-2 (Renal OCT2), as shown in Table S6 in the Supplementary Information. While EGCG, TF2a, and remdesivir are possibly cleared through other available routes such as bile, breath, faces, and sweat. EGCG remains intact in the plasma and later excreted via bile and metabolized by colon microflora. It is also expected that all the compounds are absorbable via oral prescription."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T272","span":{"begin":80,"end":87},"obj":"http://purl.obolibrary.org/obo/OBI_0100026"},{"id":"T273","span":{"begin":80,"end":87},"obj":"http://purl.obolibrary.org/obo/UBERON_0000468"},{"id":"T274","span":{"begin":285,"end":290},"obj":"http://purl.obolibrary.org/obo/UBERON_0001456"},{"id":"T275","span":{"begin":330,"end":336},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"},{"id":"T276","span":{"begin":384,"end":389},"obj":"http://purl.obolibrary.org/obo/UBERON_0001155"}],"text":"Among the five compounds, TF2b and TF3 were predicted as the substrate of renal organic cation transporter-2 (Renal OCT2), as shown in Table S6 in the Supplementary Information. While EGCG, TF2a, and remdesivir are possibly cleared through other available routes such as bile, breath, faces, and sweat. EGCG remains intact in the plasma and later excreted via bile and metabolized by colon microflora. It is also expected that all the compounds are absorbable via oral prescription."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T623","span":{"begin":35,"end":38},"obj":"Chemical"},{"id":"T624","span":{"begin":80,"end":94},"obj":"Chemical"},{"id":"T625","span":{"begin":88,"end":94},"obj":"Chemical"},{"id":"T626","span":{"begin":184,"end":188},"obj":"Chemical"},{"id":"T627","span":{"begin":200,"end":210},"obj":"Chemical"},{"id":"T628","span":{"begin":303,"end":307},"obj":"Chemical"}],"attributes":[{"id":"A623","pred":"chebi_id","subj":"T623","obj":"http://purl.obolibrary.org/obo/CHEBI_136608"},{"id":"A624","pred":"chebi_id","subj":"T624","obj":"http://purl.obolibrary.org/obo/CHEBI_25697"},{"id":"A625","pred":"chebi_id","subj":"T625","obj":"http://purl.obolibrary.org/obo/CHEBI_36916"},{"id":"A626","pred":"chebi_id","subj":"T626","obj":"http://purl.obolibrary.org/obo/CHEBI_4806"},{"id":"A627","pred":"chebi_id","subj":"T627","obj":"http://purl.obolibrary.org/obo/CHEBI_145994"},{"id":"A628","pred":"chebi_id","subj":"T628","obj":"http://purl.obolibrary.org/obo/CHEBI_4806"}],"text":"Among the five compounds, TF2b and TF3 were predicted as the substrate of renal organic cation transporter-2 (Renal OCT2), as shown in Table S6 in the Supplementary Information. While EGCG, TF2a, and remdesivir are possibly cleared through other available routes such as bile, breath, faces, and sweat. EGCG remains intact in the plasma and later excreted via bile and metabolized by colon microflora. It is also expected that all the compounds are absorbable via oral prescription."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T35","span":{"begin":80,"end":106},"obj":"http://purl.obolibrary.org/obo/GO_0015695"}],"text":"Among the five compounds, TF2b and TF3 were predicted as the substrate of renal organic cation transporter-2 (Renal OCT2), as shown in Table S6 in the Supplementary Information. While EGCG, TF2a, and remdesivir are possibly cleared through other available routes such as bile, breath, faces, and sweat. EGCG remains intact in the plasma and later excreted via bile and metabolized by colon microflora. It is also expected that all the compounds are absorbable via oral prescription."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1260","span":{"begin":26,"end":30},"obj":"Gene"},{"id":"1261","span":{"begin":116,"end":120},"obj":"Gene"},{"id":"1262","span":{"begin":184,"end":188},"obj":"Chemical"},{"id":"1263","span":{"begin":200,"end":210},"obj":"Chemical"},{"id":"1264","span":{"begin":303,"end":307},"obj":"Chemical"},{"id":"1265","span":{"begin":277,"end":283},"obj":"Disease"}],"attributes":[{"id":"A1260","pred":"tao:has_database_id","subj":"1260","obj":"Gene:2959"},{"id":"A1261","pred":"tao:has_database_id","subj":"1261","obj":"Gene:5452"},{"id":"A1262","pred":"tao:has_database_id","subj":"1262","obj":"MESH:C045651"},{"id":"A1263","pred":"tao:has_database_id","subj":"1263","obj":"MESH:C000606551"},{"id":"A1264","pred":"tao:has_database_id","subj":"1264","obj":"MESH:C045651"},{"id":"A1265","pred":"tao:has_database_id","subj":"1265","obj":"MESH:D004417"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Among the five compounds, TF2b and TF3 were predicted as the substrate of renal organic cation transporter-2 (Renal OCT2), as shown in Table S6 in the Supplementary Information. While EGCG, TF2a, and remdesivir are possibly cleared through other available routes such as bile, breath, faces, and sweat. EGCG remains intact in the plasma and later excreted via bile and metabolized by colon microflora. It is also expected that all the compounds are absorbable via oral prescription."}

{"project":"LitCovid-sentences","denotations":[{"id":"T438","span":{"begin":0,"end":177},"obj":"Sentence"},{"id":"T439","span":{"begin":178,"end":302},"obj":"Sentence"},{"id":"T440","span":{"begin":303,"end":401},"obj":"Sentence"},{"id":"T441","span":{"begin":402,"end":482},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Among the five compounds, TF2b and TF3 were predicted as the substrate of renal organic cation transporter-2 (Renal OCT2), as shown in Table S6 in the Supplementary Information. While EGCG, TF2a, and remdesivir are possibly cleared through other available routes such as bile, breath, faces, and sweat. EGCG remains intact in the plasma and later excreted via bile and metabolized by colon microflora. It is also expected that all the compounds are absorbable via oral prescription."}