PMC:7441777 / 31988-32304 JSONTXT

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T199","span":{"begin":209,"end":212},"obj":"http://purl.obolibrary.org/obo/CLO_0009325"},{"id":"T200","span":{"begin":279,"end":281},"obj":"http://purl.obolibrary.org/obo/CLO_0008922"},{"id":"T201","span":{"begin":279,"end":281},"obj":"http://purl.obolibrary.org/obo/CLO_0050052"}],"text":"The estimated binding free energy (ΔGbind) of remdesivir, EGCG, TF3, TF2b, and TF2a were −24.57, −27.02, −42.27, −26.74 and −27.17 kcal/mol, respectively (Table 4) and myricetin, quercetagetin, hesperidin and TF1 show lower binding affinity compared to that of remdesivir (Table S2 in the Supplementary Information)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T432","span":{"begin":46,"end":56},"obj":"Chemical"},{"id":"T433","span":{"begin":58,"end":62},"obj":"Chemical"},{"id":"T434","span":{"begin":64,"end":67},"obj":"Chemical"},{"id":"T435","span":{"begin":168,"end":177},"obj":"Chemical"},{"id":"T437","span":{"begin":179,"end":192},"obj":"Chemical"},{"id":"T438","span":{"begin":194,"end":204},"obj":"Chemical"},{"id":"T439","span":{"begin":261,"end":271},"obj":"Chemical"},{"id":"T440","span":{"begin":279,"end":281},"obj":"Chemical"}],"attributes":[{"id":"A432","pred":"chebi_id","subj":"T432","obj":"http://purl.obolibrary.org/obo/CHEBI_145994"},{"id":"A433","pred":"chebi_id","subj":"T433","obj":"http://purl.obolibrary.org/obo/CHEBI_4806"},{"id":"A434","pred":"chebi_id","subj":"T434","obj":"http://purl.obolibrary.org/obo/CHEBI_136608"},{"id":"A435","pred":"chebi_id","subj":"T435","obj":"http://purl.obolibrary.org/obo/CHEBI_18152"},{"id":"A436","pred":"chebi_id","subj":"T435","obj":"http://purl.obolibrary.org/obo/CHEBI_58395"},{"id":"A437","pred":"chebi_id","subj":"T437","obj":"http://purl.obolibrary.org/obo/CHEBI_8695"},{"id":"A438","pred":"chebi_id","subj":"T438","obj":"http://purl.obolibrary.org/obo/CHEBI_28775"},{"id":"A439","pred":"chebi_id","subj":"T439","obj":"http://purl.obolibrary.org/obo/CHEBI_145994"},{"id":"A440","pred":"chebi_id","subj":"T440","obj":"http://purl.obolibrary.org/obo/CHEBI_29387"}],"text":"The estimated binding free energy (ΔGbind) of remdesivir, EGCG, TF3, TF2b, and TF2a were −24.57, −27.02, −42.27, −26.74 and −27.17 kcal/mol, respectively (Table 4) and myricetin, quercetagetin, hesperidin and TF1 show lower binding affinity compared to that of remdesivir (Table S2 in the Supplementary Information)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"777","span":{"begin":69,"end":73},"obj":"Gene"},{"id":"784","span":{"begin":46,"end":56},"obj":"Chemical"},{"id":"785","span":{"begin":58,"end":62},"obj":"Chemical"},{"id":"786","span":{"begin":168,"end":177},"obj":"Chemical"},{"id":"787","span":{"begin":179,"end":192},"obj":"Chemical"},{"id":"788","span":{"begin":194,"end":204},"obj":"Chemical"},{"id":"789","span":{"begin":261,"end":271},"obj":"Chemical"}],"attributes":[{"id":"A777","pred":"tao:has_database_id","subj":"777","obj":"Gene:2959"},{"id":"A784","pred":"tao:has_database_id","subj":"784","obj":"MESH:C000606551"},{"id":"A785","pred":"tao:has_database_id","subj":"785","obj":"MESH:C045651"},{"id":"A786","pred":"tao:has_database_id","subj":"786","obj":"MESH:C040015"},{"id":"A787","pred":"tao:has_database_id","subj":"787","obj":"MESH:C079163"},{"id":"A788","pred":"tao:has_database_id","subj":"788","obj":"MESH:D006569"},{"id":"A789","pred":"tao:has_database_id","subj":"789","obj":"MESH:C000606551"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The estimated binding free energy (ΔGbind) of remdesivir, EGCG, TF3, TF2b, and TF2a were −24.57, −27.02, −42.27, −26.74 and −27.17 kcal/mol, respectively (Table 4) and myricetin, quercetagetin, hesperidin and TF1 show lower binding affinity compared to that of remdesivir (Table S2 in the Supplementary Information)."}

{"project":"LitCovid-PD-GlycoEpitope","denotations":[{"id":"T15","span":{"begin":209,"end":212},"obj":"GlycoEpitope"}],"attributes":[{"id":"A15","pred":"glyco_epitope_db_id","subj":"T15","obj":"http://www.glycoepitope.jp/epitopes/AN0049"}],"text":"The estimated binding free energy (ΔGbind) of remdesivir, EGCG, TF3, TF2b, and TF2a were −24.57, −27.02, −42.27, −26.74 and −27.17 kcal/mol, respectively (Table 4) and myricetin, quercetagetin, hesperidin and TF1 show lower binding affinity compared to that of remdesivir (Table S2 in the Supplementary Information)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T302","span":{"begin":0,"end":316},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The estimated binding free energy (ΔGbind) of remdesivir, EGCG, TF3, TF2b, and TF2a were −24.57, −27.02, −42.27, −26.74 and −27.17 kcal/mol, respectively (Table 4) and myricetin, quercetagetin, hesperidin and TF1 show lower binding affinity compared to that of remdesivir (Table S2 in the Supplementary Information)."}