PMC:7441777 / 29127-29573 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7441777","sourcedb":"PMC","sourceid":"7441777","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7441777","text":"of the binding free energy of EGCG, TF3, TF2b, and TF2a are reported in Table 4. The remaining four polyphenols which showed lower estimated affinity compare to remdesivir are shown in Table S2 in Supplementary Information. It can be noted from Figure 4 that the intermolecular van der Waals (ΔEvdW) and electrostatic (ΔEelec) terms are favorable for the ligand binding, whereas the desolvation of polar groups (ΔGpol) opposes the complex formati","tracks":[{"project":"LitCovid-PD-CLO","denotations":[{"id":"T188","span":{"begin":191,"end":193},"obj":"http://purl.obolibrary.org/obo/CLO_0008922"},{"id":"T189","span":{"begin":191,"end":193},"obj":"http://purl.obolibrary.org/obo/CLO_0050052"}],"attributes":[{"subj":"T188","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T189","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T410","span":{"begin":30,"end":34},"obj":"Chemical"},{"id":"T411","span":{"begin":36,"end":39},"obj":"Chemical"},{"id":"T412","span":{"begin":100,"end":111},"obj":"Chemical"},{"id":"T413","span":{"begin":161,"end":171},"obj":"Chemical"},{"id":"T414","span":{"begin":191,"end":193},"obj":"Chemical"},{"id":"T415","span":{"begin":355,"end":361},"obj":"Chemical"}],"attributes":[{"id":"A410","pred":"chebi_id","subj":"T410","obj":"http://purl.obolibrary.org/obo/CHEBI_4806"},{"id":"A411","pred":"chebi_id","subj":"T411","obj":"http://purl.obolibrary.org/obo/CHEBI_136608"},{"id":"A412","pred":"chebi_id","subj":"T412","obj":"http://purl.obolibrary.org/obo/CHEBI_26195"},{"id":"A413","pred":"chebi_id","subj":"T413","obj":"http://purl.obolibrary.org/obo/CHEBI_145994"},{"id":"A414","pred":"chebi_id","subj":"T414","obj":"http://purl.obolibrary.org/obo/CHEBI_29387"},{"id":"A415","pred":"chebi_id","subj":"T415","obj":"http://purl.obolibrary.org/obo/CHEBI_52214"},{"subj":"T410","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T411","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T412","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T413","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T414","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T415","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"708","span":{"begin":41,"end":45},"obj":"Gene"},{"id":"713","span":{"begin":30,"end":34},"obj":"Chemical"},{"id":"714","span":{"begin":100,"end":111},"obj":"Chemical"},{"id":"715","span":{"begin":161,"end":171},"obj":"Chemical"}],"attributes":[{"id":"A708","pred":"tao:has_database_id","subj":"708","obj":"Gene:2959"},{"id":"A713","pred":"tao:has_database_id","subj":"713","obj":"MESH:C045651"},{"id":"A714","pred":"tao:has_database_id","subj":"714","obj":"MESH:D059808"},{"id":"A715","pred":"tao:has_database_id","subj":"715","obj":"MESH:C000606551"},{"subj":"708","pred":"source","obj":"LitCovid-PubTator"},{"subj":"713","pred":"source","obj":"LitCovid-PubTator"},{"subj":"714","pred":"source","obj":"LitCovid-PubTator"},{"subj":"715","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T276","span":{"begin":81,"end":223},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T276","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-CLO","color":"#db93ec","default":true},{"id":"LitCovid-PD-CHEBI","color":"#93ecc1"},{"id":"LitCovid-PubTator","color":"#eca793"},{"id":"LitCovid-sentences","color":"#9398ec"}]}]}}