PMC:7441777 / 18760-19310 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T33","span":{"begin":84,"end":92},"obj":"Body_part"}],"attributes":[{"id":"A33","pred":"fma_id","subj":"T33","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"2.5. Molecular target prediction\nNatural compounds interact with a large number of proteins, enzymes, lipids. This interaction plays a crucial role in elucidating the molecular mechanism of the small molecules. So, it is important to identify the molecular targets for new molecules (Gfeller et al., 2014). Swiss Target Prediction website (http://www.swisstargetprediction.ch/index.php) was logged on, and canonical SMILE molecular structures of remdesivir, EGCG, TF2a, TF2b, and TF3 were entered in the search bar option, and results were analyzed."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T113","span":{"begin":66,"end":67},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T114","span":{"begin":134,"end":135},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"2.5. Molecular target prediction\nNatural compounds interact with a large number of proteins, enzymes, lipids. This interaction plays a crucial role in elucidating the molecular mechanism of the small molecules. So, it is important to identify the molecular targets for new molecules (Gfeller et al., 2014). Swiss Target Prediction website (http://www.swisstargetprediction.ch/index.php) was logged on, and canonical SMILE molecular structures of remdesivir, EGCG, TF2a, TF2b, and TF3 were entered in the search bar option, and results were analyzed."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T266","span":{"begin":84,"end":92},"obj":"Chemical"},{"id":"T267","span":{"begin":103,"end":109},"obj":"Chemical"},{"id":"T268","span":{"begin":201,"end":210},"obj":"Chemical"},{"id":"T269","span":{"begin":274,"end":283},"obj":"Chemical"},{"id":"T270","span":{"begin":447,"end":457},"obj":"Chemical"},{"id":"T271","span":{"begin":459,"end":463},"obj":"Chemical"},{"id":"T272","span":{"begin":481,"end":484},"obj":"Chemical"}],"attributes":[{"id":"A266","pred":"chebi_id","subj":"T266","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A267","pred":"chebi_id","subj":"T267","obj":"http://purl.obolibrary.org/obo/CHEBI_18059"},{"id":"A268","pred":"chebi_id","subj":"T268","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A269","pred":"chebi_id","subj":"T269","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A270","pred":"chebi_id","subj":"T270","obj":"http://purl.obolibrary.org/obo/CHEBI_145994"},{"id":"A271","pred":"chebi_id","subj":"T271","obj":"http://purl.obolibrary.org/obo/CHEBI_4806"},{"id":"A272","pred":"chebi_id","subj":"T272","obj":"http://purl.obolibrary.org/obo/CHEBI_136608"}],"text":"2.5. Molecular target prediction\nNatural compounds interact with a large number of proteins, enzymes, lipids. This interaction plays a crucial role in elucidating the molecular mechanism of the small molecules. So, it is important to identify the molecular targets for new molecules (Gfeller et al., 2014). Swiss Target Prediction website (http://www.swisstargetprediction.ch/index.php) was logged on, and canonical SMILE molecular structures of remdesivir, EGCG, TF2a, TF2b, and TF3 were entered in the search bar option, and results were analyzed."}

{"project":"LitCovid-PubTator","denotations":[{"id":"406","span":{"begin":471,"end":475},"obj":"Gene"},{"id":"407","span":{"begin":417,"end":422},"obj":"Gene"},{"id":"408","span":{"begin":103,"end":109},"obj":"Chemical"},{"id":"409","span":{"begin":447,"end":457},"obj":"Chemical"}],"attributes":[{"id":"A406","pred":"tao:has_database_id","subj":"406","obj":"Gene:2959"},{"id":"A408","pred":"tao:has_database_id","subj":"408","obj":"MESH:D008055"},{"id":"A409","pred":"tao:has_database_id","subj":"409","obj":"MESH:C000606551"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"2.5. Molecular target prediction\nNatural compounds interact with a large number of proteins, enzymes, lipids. This interaction plays a crucial role in elucidating the molecular mechanism of the small molecules. So, it is important to identify the molecular targets for new molecules (Gfeller et al., 2014). Swiss Target Prediction website (http://www.swisstargetprediction.ch/index.php) was logged on, and canonical SMILE molecular structures of remdesivir, EGCG, TF2a, TF2b, and TF3 were entered in the search bar option, and results were analyzed."}

{"project":"LitCovid-sentences","denotations":[{"id":"T186","span":{"begin":0,"end":4},"obj":"Sentence"},{"id":"T187","span":{"begin":6,"end":33},"obj":"Sentence"},{"id":"T188","span":{"begin":34,"end":110},"obj":"Sentence"},{"id":"T189","span":{"begin":111,"end":211},"obj":"Sentence"},{"id":"T190","span":{"begin":212,"end":307},"obj":"Sentence"},{"id":"T191","span":{"begin":308,"end":550},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"2.5. Molecular target prediction\nNatural compounds interact with a large number of proteins, enzymes, lipids. This interaction plays a crucial role in elucidating the molecular mechanism of the small molecules. So, it is important to identify the molecular targets for new molecules (Gfeller et al., 2014). Swiss Target Prediction website (http://www.swisstargetprediction.ch/index.php) was logged on, and canonical SMILE molecular structures of remdesivir, EGCG, TF2a, TF2b, and TF3 were entered in the search bar option, and results were analyzed."}

{"project":"2_test","denotations":[{"id":"32720577-24792161-56195125","span":{"begin":301,"end":305},"obj":"24792161"}],"text":"2.5. Molecular target prediction\nNatural compounds interact with a large number of proteins, enzymes, lipids. This interaction plays a crucial role in elucidating the molecular mechanism of the small molecules. So, it is important to identify the molecular targets for new molecules (Gfeller et al., 2014). Swiss Target Prediction website (http://www.swisstargetprediction.ch/index.php) was logged on, and canonical SMILE molecular structures of remdesivir, EGCG, TF2a, TF2b, and TF3 were entered in the search bar option, and results were analyzed."}