PMC:7436876
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T1 | 6-13 | Body_part | denotes | abdomen | http://purl.org/sig/ont/fma/fma9577 |
| T2 | 110-117 | Body_part | denotes | abdomen | http://purl.org/sig/ont/fma/fma9577 |
| T3 | 223-230 | Body_part | denotes | abdomen | http://purl.org/sig/ont/fma/fma9577 |
| T4 | 334-341 | Body_part | denotes | abdomen | http://purl.org/sig/ont/fma/fma9577 |
| T5 | 667-674 | Body_part | denotes | abdomen | http://purl.org/sig/ont/fma/fma9577 |
| T6 | 914-919 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
| T7 | 1414-1421 | Body_part | denotes | abdomen | http://purl.org/sig/ont/fma/fma9577 |
| T8 | 1535-1542 | Body_part | denotes | abdomen | http://purl.org/sig/ont/fma/fma9577 |
| T9 | 1669-1676 | Body_part | denotes | abdomen | http://purl.org/sig/ont/fma/fma9577 |
| T10 | 1777-1782 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
| T11 | 1864-1871 | Body_part | denotes | abdomen | http://purl.org/sig/ont/fma/fma9577 |
| T12 | 1882-1887 | Body_part | denotes | chest | http://purl.org/sig/ont/fma/fma9576 |
| T13 | 2033-2040 | Body_part | denotes | abdomen | http://purl.org/sig/ont/fma/fma9577 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 6-13 | Body_part | denotes | abdomen | http://purl.obolibrary.org/obo/UBERON_0000916 |
| T2 | 110-117 | Body_part | denotes | abdomen | http://purl.obolibrary.org/obo/UBERON_0000916 |
| T3 | 223-230 | Body_part | denotes | abdomen | http://purl.obolibrary.org/obo/UBERON_0000916 |
| T4 | 334-341 | Body_part | denotes | abdomen | http://purl.obolibrary.org/obo/UBERON_0000916 |
| T5 | 667-674 | Body_part | denotes | abdomen | http://purl.obolibrary.org/obo/UBERON_0000916 |
| T6 | 1243-1249 | Body_part | denotes | vessel | http://purl.obolibrary.org/obo/UBERON_0000055 |
| T7 | 1295-1302 | Body_part | denotes | vessels | http://purl.obolibrary.org/obo/UBERON_0000055 |
| T8 | 1414-1421 | Body_part | denotes | abdomen | http://purl.obolibrary.org/obo/UBERON_0000916 |
| T9 | 1535-1542 | Body_part | denotes | abdomen | http://purl.obolibrary.org/obo/UBERON_0000916 |
| T10 | 1669-1676 | Body_part | denotes | abdomen | http://purl.obolibrary.org/obo/UBERON_0000916 |
| T11 | 1777-1782 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
| T12 | 1864-1871 | Body_part | denotes | abdomen | http://purl.obolibrary.org/obo/UBERON_0000916 |
| T13 | 1882-1887 | Body_part | denotes | chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
| T14 | 2033-2040 | Body_part | denotes | abdomen | http://purl.obolibrary.org/obo/UBERON_0000916 |
| T15 | 2075-2082 | Body_part | denotes | vessels | http://purl.obolibrary.org/obo/UBERON_0000055 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 46-54 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T2 | 64-72 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T3 | 246-254 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T4 | 290-294 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T5 | 301-310 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T6 | 682-690 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T7 | 936-940 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T8 | 952-956 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T9 | 962-971 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T10 | 1002-1012 | Disease | denotes | thrombosis | http://purl.obolibrary.org/obo/MONDO_0000831 |
| T11 | 1140-1152 | Disease | denotes | pancreatitis | http://purl.obolibrary.org/obo/MONDO_0004982 |
| T12 | 1154-1165 | Disease | denotes | peritonitis | http://purl.obolibrary.org/obo/MONDO_0004522 |
| T13 | 1191-1198 | Disease | denotes | colitis | http://purl.obolibrary.org/obo/MONDO_0005292 |
| T14 | 1250-1258 | Disease | denotes | ischemia | http://purl.obolibrary.org/obo/MONDO_0005053 |
| T15 | 1368-1376 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T16 | 1561-1565 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T17 | 1572-1581 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T18 | 1804-1812 | Disease | denotes | COVID‐19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T19 | 2194-2204 | Disease | denotes | infectious | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 6-13 | http://purl.obolibrary.org/obo/UBERON_0000916 | denotes | abdomen |
| T2 | 6-13 | http://www.ebi.ac.uk/efo/EFO_0000968 | denotes | abdomen |
| T3 | 110-117 | http://purl.obolibrary.org/obo/UBERON_0000916 | denotes | abdomen |
| T4 | 110-117 | http://www.ebi.ac.uk/efo/EFO_0000968 | denotes | abdomen |
| T5 | 223-230 | http://purl.obolibrary.org/obo/UBERON_0000916 | denotes | abdomen |
| T6 | 223-230 | http://www.ebi.ac.uk/efo/EFO_0000968 | denotes | abdomen |
| T7 | 334-341 | http://purl.obolibrary.org/obo/UBERON_0000916 | denotes | abdomen |
| T8 | 334-341 | http://www.ebi.ac.uk/efo/EFO_0000968 | denotes | abdomen |
| T9 | 667-674 | http://purl.obolibrary.org/obo/UBERON_0000916 | denotes | abdomen |
| T10 | 667-674 | http://www.ebi.ac.uk/efo/EFO_0000968 | denotes | abdomen |
| T11 | 843-844 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T12 | 914-919 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
| T13 | 1167-1174 | http://purl.obolibrary.org/obo/UBERON_0001155 | denotes | colonic |
| T14 | 1243-1249 | http://purl.obolibrary.org/obo/UBERON_0000055 | denotes | vessel |
| T15 | 1295-1302 | http://purl.obolibrary.org/obo/UBERON_0000055 | denotes | vessels |
| T16 | 1313-1325 | http://purl.obolibrary.org/obo/UBERON_0000026 | denotes | appendagitis |
| T17 | 1313-1325 | http://www.ebi.ac.uk/efo/EFO_0000799 | denotes | appendagitis |
| T18 | 1414-1421 | http://purl.obolibrary.org/obo/UBERON_0000916 | denotes | abdomen |
| T19 | 1414-1421 | http://www.ebi.ac.uk/efo/EFO_0000968 | denotes | abdomen |
| T20 | 1482-1483 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T21 | 1535-1542 | http://purl.obolibrary.org/obo/UBERON_0000916 | denotes | abdomen |
| T22 | 1535-1542 | http://www.ebi.ac.uk/efo/EFO_0000968 | denotes | abdomen |
| T23 | 1669-1676 | http://purl.obolibrary.org/obo/UBERON_0000916 | denotes | abdomen |
| T24 | 1669-1676 | http://www.ebi.ac.uk/efo/EFO_0000968 | denotes | abdomen |
| T25 | 1687-1693 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tested |
| T26 | 1864-1871 | http://purl.obolibrary.org/obo/UBERON_0000916 | denotes | abdomen |
| T27 | 1864-1871 | http://www.ebi.ac.uk/efo/EFO_0000968 | denotes | abdomen |
| T28 | 1882-1887 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | chest |
| T29 | 2011-2012 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T30 | 2033-2040 | http://purl.obolibrary.org/obo/UBERON_0000916 | denotes | abdomen |
| T31 | 2033-2040 | http://www.ebi.ac.uk/efo/EFO_0000968 | denotes | abdomen |
| T32 | 2042-2050 | http://purl.obolibrary.org/obo/CLO_0009985 | denotes | focusing |
| T33 | 2075-2082 | http://purl.obolibrary.org/obo/UBERON_0000055 | denotes | vessels |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1 | 446-457 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 501-513 | http://purl.obolibrary.org/obo/GO_0009405 | denotes | pathogenesis |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-63 | Sentence | denotes | Acute abdomen is not always surgical amid the COVID‐19 pandemic |
| T2 | 64-117 | Sentence | denotes | COVID‐19 related‐non‐surgical causes of acute abdomen |
| T3 | 120-126 | Sentence | denotes | Editor |
| T4 | 128-262 | Sentence | denotes | Lima et al.'s recently published paper discussed the role of imaging in the diagnosis of acute abdomen cases amid the COVID‐19 era 1 . |
| T5 | 263-410 | Sentence | denotes | Saeed et al. reported that SARS‐CoV‐2 infection could lead to an acute abdomen‐like presentation in the absence of identifiable surgical causes 2 . |
| T6 | 411-529 | Sentence | denotes | Both authors discussed the role of angiotensin‐converting‐enzyme‐2 (ACE2) receptor in the pathogenesis of this entity. |
| T7 | 530-601 | Sentence | denotes | Our experience with similar cases makes us concur with both authors 3 . |
| T8 | 602-767 | Sentence | denotes | Herein we will summarize the likely non‐surgical causes of acute abdomen in the COVID‐19 era and discuss important management points when dealing with such patients. |
| T9 | 768-842 | Sentence | denotes | The causes can be divided into respiratory and non‐respiratory (Fig. 1 ). |
| T10 | 843-947 | Sentence | denotes | A respiratory cause for such presentation is pain referring from lower lungs involved by the SARS‐CoV‐2. |
| T11 | 948-1109 | Sentence | denotes | The SARS‐CoV2 infection seems to increase the risk of thrombosis 4 ; thus, the non‐respiratory causes can be further classified as thrombotic and non‐thrombotic. |
| T12 | 1110-1359 | Sentence | denotes | Non‐thrombotic causes include pancreatitis, peritonitis, colonic distension, and colitis, while thrombotic etiologies are mesenteric vessel ischemia (occlusive or non‐occlusive), renal vessels infarcts, appendagitis, and omental infarcts (Fig. 1 ). |
| T13 | 1360-1630 | Sentence | denotes | Fig. 1 COVID‐19‐related non‐surgical causes of acute abdomen With the causes mentioned above in mind, it is wise to keep a broad differential of non‐surgical causes of acute abdomen in the setting of SARS‐CoV‐2 infection, to avoid unnecessary surgical interventions 5 . |
| T14 | 1631-1767 | Sentence | denotes | Any patients presenting with an acute abdomen should be tested and retested for SRAS‐CoV‐2, even in the absence of respiratory symptoms. |
| T15 | 1768-1826 | Sentence | denotes | Elevated serum ferritin may support COVID‐19 diagnosis 3 . |
| T16 | 1827-1972 | Sentence | denotes | Computed tomography (CT) scan of the abdomen and lower chest will be valuable in ruling some of the causes and identifying pulmonary involvement. |
| T17 | 1973-2083 | Sentence | denotes | If unrevealing, we suggest performing a CT angiogram of the abdomen, focusing on mesenteric and renal vessels. |
| T18 | 2084-2276 | Sentence | denotes | We believe in the role of multidisciplinary meetings (MDT), including radiologists, surgeons, internists, and infectious experts, to tailor an individualized, case‐by‐case management approach. |
| T19 | 2278-2299 | Sentence | denotes | Author's contribution |
| T20 | 2300-2347 | Sentence | denotes | MFHM and KA contributed equally to this letter. |
| T21 | 2348-2431 | Sentence | denotes | KA and MFHM wrote the initial and the final version and approved it for submission. |
| T22 | 2433-2448 | Sentence | denotes | Acknowledgement |
| T23 | 2449-2544 | Sentence | denotes | We acknowledge the editor and the editorial team members for their prompt review of the letter. |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 888-892 | Phenotype | denotes | pain | http://purl.obolibrary.org/obo/HP_0012531 |
| T2 | 1140-1152 | Phenotype | denotes | pancreatitis | http://purl.obolibrary.org/obo/HP_0001733 |
| T3 | 1154-1165 | Phenotype | denotes | peritonitis | http://purl.obolibrary.org/obo/HP_0002586 |
| T4 | 1191-1198 | Phenotype | denotes | colitis | http://purl.obolibrary.org/obo/HP_0002583 |
| T5 | 1768-1791 | Phenotype | denotes | Elevated serum ferritin | http://purl.obolibrary.org/obo/HP_0003281 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1 | 46-54 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 8 | 446-477 | Gene | denotes | angiotensin‐converting‐enzyme‐2 | Gene:59272 |
| 9 | 479-483 | Gene | denotes | ACE2 | Gene:59272 |
| 10 | 758-766 | Species | denotes | patients | Tax:9606 |
| 11 | 246-254 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 12 | 295-310 | Disease | denotes | CoV‐2 infection | MESH:C000657245 |
| 13 | 682-690 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 25 | 936-946 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
| 26 | 952-961 | Species | denotes | SARS‐CoV2 | Tax:2697049 |
| 27 | 888-892 | Disease | denotes | pain | MESH:D010146 |
| 28 | 962-971 | Disease | denotes | infection | MESH:D007239 |
| 29 | 1002-1012 | Disease | denotes | thrombosis | MESH:D013927 |
| 30 | 1140-1152 | Disease | denotes | pancreatitis | MESH:D010195 |
| 31 | 1154-1165 | Disease | denotes | peritonitis | MESH:D010534 |
| 32 | 1167-1174 | Disease | denotes | colonic | MESH:D003110 |
| 33 | 1191-1198 | Disease | denotes | colitis | MESH:D003092 |
| 34 | 1250-1325 | Disease | denotes | ischemia (occlusive or non‐occlusive), renal vessels infarcts, appendagitis | MESH:D065666 |
| 35 | 1331-1347 | Disease | denotes | omental infarcts | MESH:D015436 |
| 37 | 1368-1376 | Disease | denotes | COVID‐19 | MESH:C000657245 |
| 43 | 1635-1643 | Species | denotes | patients | Tax:9606 |
| 44 | 1716-1721 | Species | denotes | CoV‐2 | Tax:2697049 |
| 45 | 1561-1581 | Disease | denotes | SARS‐CoV‐2 infection | MESH:C000657245 |
| 46 | 1746-1766 | Disease | denotes | respiratory symptoms | MESH:D012818 |
| 47 | 1804-1812 | Disease | denotes | COVID‐19 | MESH:C000657245 |