PMC:7435837 / 2541-6183 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7435837","sourcedb":"PMC","sourceid":"7435837","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7435837","text":"2. The Cell Entry Mechanism of Encapsulated Viruses\nEncapsulated viruses such as the SARS-CoV and SARS-CoV-2 viruses comprise of some general surface constituents. The surface envelope or capsule is presented as a lipid bilayer membrane that contains various envelope proteins (E), membrane proteins (M), and an outer layer that presents so-called spike (S) proteins [1]. M and S proteins are generally rich in sugar molecules that form a so-called glycan structure. N- or O-glycosylate moieties are commonly found in the viral S proteins and they can recognize some cell receptors to which the virion can bind [2,3]. These spike proteins facilitate virion entry into host cells. Encapsulated viruses such as the coronaviruses present approximately 200 of these spiky structures [4]. Spike proteins are comprised of glycoproteins, proteins that also contain polysaccharide or oligosaccharide moieties otherwise known as glycans [5,6,7].\nThe glycoproteins have a variety of functions that maintain the virion structure and properties such as water solubility, creation of diffusion barriers, and antiadhesive actions among others [6]. In addition to the intrinsic functions that glycoproteins afford to the maintenance of the virion structure, they also act as a structure that recognizes glycan-binding proteins presented on the membranes of potential host cells [1]. The viral glycans may be recognized by bacterial, fungal, and parasite-associated glycan-binding proteins. However, viruses are also recognized by host cells via the same mechanism. It is this form of intercellular recognition interactions that prove vital to effect the virus entry into host cells in which the virus could replicate [7].\nA detailed description of the spike glycoproteins of SARS-CoV-2 reported that two binding subunits can be distinguished. These subunits become active when the two units are cleaved by host cell proteases on the host cell membrane. Subunit, S1 is responsible for binding to the host cell membrane and subunit, S2 is responsible for fusion of the virion and host cell membranes. The S1 unit is the factor that makes various coronaviruses specific toward a certain host [8]. Pulmonary angiotensin-converting-enzyme 2 (ACE-2) in humans exhibit the appropriate receptor, a specific sequence of amino acid residues [9], towards S1 and partly explains the effective spread of the coronaviruses via droplets in the atmosphere [10].\nAs part of the human host immune responses, the glycans of the coronavirus spike protein subunits are recognized by dendritic cells [11] in the blood which binds to the glycan and subsequently expresses CD4+ and CD8+ glycopeptides. These glycopeptides label the spike protein and this labeled protein is then presented to T-cells [12]. T-cells subsequently recognize the labels, phagocytose these antigen-marked viruses, and degrade them. It has been found that the glycan-binding proteins, also known as lectins [5], can impart broad-spectrum binding properties against HIV-1, SARS-CoV, and human cytomegalovirus. The lectin which is capable of showing broad interaction via oligomannosyl antigens is known as lectin GNA (Galanthus nivalis agglutinin). The N-oligomannosyl cores are embedded in N-glycans which are commonly expressed on the surface of numerous viral pathogens [13]. Once the lectin binds to the glycan, the virus structure may undergo conformational changes that result in the fusion of the virus and host to facilitate virus entry. S-proteins are specifically responsible for host cell entry by coronaviruses [14]. Figure 1 depicts a simplified entry mechanism of the viruses into host cells.","divisions":[{"label":"title","span":{"begin":0,"end":51}},{"label":"p","span":{"begin":52,"end":936}},{"label":"p","span":{"begin":937,"end":1706}},{"label":"p","span":{"begin":1707,"end":2430}}],"tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T6","span":{"begin":7,"end":11},"obj":"Body_part"},{"id":"T7","span":{"begin":188,"end":195},"obj":"Body_part"},{"id":"T8","span":{"begin":214,"end":219},"obj":"Body_part"},{"id":"T9","span":{"begin":268,"end":276},"obj":"Body_part"},{"id":"T10","span":{"begin":291,"end":299},"obj":"Body_part"},{"id":"T11","span":{"begin":358,"end":366},"obj":"Body_part"},{"id":"T12","span":{"begin":380,"end":388},"obj":"Body_part"},{"id":"T13","span":{"begin":411,"end":416},"obj":"Body_part"},{"id":"T14","span":{"begin":530,"end":538},"obj":"Body_part"},{"id":"T15","span":{"begin":567,"end":571},"obj":"Body_part"},{"id":"T16","span":{"begin":630,"end":638},"obj":"Body_part"},{"id":"T17","span":{"begin":673,"end":678},"obj":"Body_part"},{"id":"T18","span":{"begin":790,"end":798},"obj":"Body_part"},{"id":"T19","span":{"begin":816,"end":829},"obj":"Body_part"},{"id":"T20","span":{"begin":831,"end":839},"obj":"Body_part"},{"id":"T21","span":{"begin":858,"end":872},"obj":"Body_part"},{"id":"T22","span":{"begin":876,"end":891},"obj":"Body_part"},{"id":"T23","span":{"begin":941,"end":954},"obj":"Body_part"},{"id":"T24","span":{"begin":1178,"end":1191},"obj":"Body_part"},{"id":"T25","span":{"begin":1303,"end":1311},"obj":"Body_part"},{"id":"T26","span":{"begin":1357,"end":1362},"obj":"Body_part"},{"id":"T27","span":{"begin":1465,"end":1473},"obj":"Body_part"},{"id":"T28","span":{"begin":1520,"end":1525},"obj":"Body_part"},{"id":"T29","span":{"begin":1661,"end":1666},"obj":"Body_part"},{"id":"T30","span":{"begin":1743,"end":1756},"obj":"Body_part"},{"id":"T31","span":{"begin":1896,"end":1900},"obj":"Body_part"},{"id":"T32","span":{"begin":1923,"end":1936},"obj":"Body_part"},{"id":"T33","span":{"begin":1923,"end":1927},"obj":"Body_part"},{"id":"T34","span":{"begin":1989,"end":2002},"obj":"Body_part"},{"id":"T35","span":{"begin":1989,"end":1993},"obj":"Body_part"},{"id":"T36","span":{"begin":2068,"end":2082},"obj":"Body_part"},{"id":"T37","span":{"begin":2068,"end":2072},"obj":"Body_part"},{"id":"T38","span":{"begin":2296,"end":2306},"obj":"Body_part"},{"id":"T39","span":{"begin":2512,"end":2519},"obj":"Body_part"},{"id":"T40","span":{"begin":2547,"end":2562},"obj":"Body_part"},{"id":"T41","span":{"begin":2557,"end":2562},"obj":"Body_part"},{"id":"T42","span":{"begin":2575,"end":2580},"obj":"Body_part"},{"id":"T43","span":{"begin":2648,"end":2661},"obj":"Body_part"},{"id":"T44","span":{"begin":2669,"end":2682},"obj":"Body_part"},{"id":"T45","span":{"begin":2699,"end":2706},"obj":"Body_part"},{"id":"T46","span":{"begin":2724,"end":2731},"obj":"Body_part"},{"id":"T47","span":{"begin":2755,"end":2760},"obj":"Body_part"},{"id":"T48","span":{"begin":2769,"end":2774},"obj":"Body_part"},{"id":"T49","span":{"begin":2912,"end":2920},"obj":"Body_part"},{"id":"T50","span":{"begin":3002,"end":3005},"obj":"Body_part"},{"id":"T51","span":{"begin":3484,"end":3492},"obj":"Body_part"},{"id":"T52","span":{"begin":3531,"end":3535},"obj":"Body_part"},{"id":"T53","span":{"begin":3636,"end":3641},"obj":"Body_part"}],"attributes":[{"id":"A6","pred":"fma_id","subj":"T6","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A7","pred":"fma_id","subj":"T7","obj":"http://purl.org/sig/ont/fma/fma85272"},{"id":"A8","pred":"fma_id","subj":"T8","obj":"http://purl.org/sig/ont/fma/fma67264"},{"id":"A9","pred":"fma_id","subj":"T9","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A10","pred":"fma_id","subj":"T10","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A11","pred":"fma_id","subj":"T11","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A12","pred":"fma_id","subj":"T12","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A13","pred":"fma_id","subj":"T13","obj":"http://purl.org/sig/ont/fma/fma82737"},{"id":"A14","pred":"fma_id","subj":"T14","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A15","pred":"fma_id","subj":"T15","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A16","pred":"fma_id","subj":"T16","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A17","pred":"fma_id","subj":"T17","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A18","pred":"fma_id","subj":"T18","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A19","pred":"fma_id","subj":"T19","obj":"http://purl.org/sig/ont/fma/fma62925"},{"id":"A20","pred":"fma_id","subj":"T20","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A21","pred":"fma_id","subj":"T21","obj":"http://purl.org/sig/ont/fma/fma82746"},{"id":"A22","pred":"fma_id","subj":"T22","obj":"http://purl.org/sig/ont/fma/fma82742"},{"id":"A23","pred":"fma_id","subj":"T23","obj":"http://purl.org/sig/ont/fma/fma62925"},{"id":"A24","pred":"fma_id","subj":"T24","obj":"http://purl.org/sig/ont/fma/fma62925"},{"id":"A25","pred":"fma_id","subj":"T25","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A26","pred":"fma_id","subj":"T26","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A27","pred":"fma_id","subj":"T27","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A28","pred":"fma_id","subj":"T28","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A29","pred":"fma_id","subj":"T29","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A30","pred":"fma_id","subj":"T30","obj":"http://purl.org/sig/ont/fma/fma62925"},{"id":"A31","pred":"fma_id","subj":"T31","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A32","pred":"fma_id","subj":"T32","obj":"http://purl.org/sig/ont/fma/fma63841"},{"id":"A33","pred":"fma_id","subj":"T33","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A34","pred":"fma_id","subj":"T34","obj":"http://purl.org/sig/ont/fma/fma63841"},{"id":"A35","pred":"fma_id","subj":"T35","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A36","pred":"fma_id","subj":"T36","obj":"http://purl.org/sig/ont/fma/fma63841"},{"id":"A37","pred":"fma_id","subj":"T37","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A38","pred":"fma_id","subj":"T38","obj":"http://purl.org/sig/ont/fma/fma82739"},{"id":"A39","pred":"fma_id","subj":"T39","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A40","pred":"fma_id","subj":"T40","obj":"http://purl.org/sig/ont/fma/fma273565"},{"id":"A41","pred":"fma_id","subj":"T41","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A42","pred":"fma_id","subj":"T42","obj":"http://purl.org/sig/ont/fma/fma9670"},{"id":"A43","pred":"fma_id","subj":"T43","obj":"http://purl.org/sig/ont/fma/fma82784"},{"id":"A44","pred":"fma_id","subj":"T44","obj":"http://purl.org/sig/ont/fma/fma82784"},{"id":"A45","pred":"fma_id","subj":"T45","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A46","pred":"fma_id","subj":"T46","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A47","pred":"fma_id","subj":"T47","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A48","pred":"fma_id","subj":"T48","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A49","pred":"fma_id","subj":"T49","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A50","pred":"fma_id","subj":"T50","obj":"http://purl.org/sig/ont/fma/fma278683"},{"id":"A51","pred":"fma_id","subj":"T51","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A52","pred":"fma_id","subj":"T52","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A53","pred":"fma_id","subj":"T53","obj":"http://purl.org/sig/ont/fma/fma68646"},{"subj":"T6","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T7","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T8","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T9","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T10","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T11","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T12","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T13","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T14","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T15","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T16","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T17","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T18","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T19","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T20","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T21","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T22","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T23","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T24","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T25","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T26","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T27","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T28","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T29","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T30","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T31","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T32","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T33","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T34","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T35","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T36","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T37","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T38","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T39","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T40","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T41","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T42","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T43","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T44","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T45","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T46","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T47","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T48","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T49","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T50","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T51","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T52","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T53","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T1","span":{"begin":188,"end":195},"obj":"Body_part"},{"id":"T2","span":{"begin":2575,"end":2580},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0003893"},{"id":"A2","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"subj":"T1","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T2","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T3","span":{"begin":85,"end":93},"obj":"Disease"},{"id":"T4","span":{"begin":98,"end":106},"obj":"Disease"},{"id":"T5","span":{"begin":1760,"end":1768},"obj":"Disease"},{"id":"T6","span":{"begin":3009,"end":3017},"obj":"Disease"}],"attributes":[{"id":"A3","pred":"mondo_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A6","pred":"mondo_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"subj":"T3","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T4","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T5","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T6","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T19","span":{"begin":7,"end":11},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T20","span":{"begin":44,"end":51},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T21","span":{"begin":65,"end":72},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T22","span":{"begin":109,"end":116},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T23","span":{"begin":212,"end":213},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T24","span":{"begin":228,"end":236},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T25","span":{"begin":282,"end":290},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T26","span":{"begin":437,"end":438},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T27","span":{"begin":567,"end":571},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T28","span":{"begin":673,"end":678},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T29","span":{"begin":693,"end":700},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T30","span":{"begin":960,"end":961},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T31","span":{"begin":1260,"end":1261},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T32","span":{"begin":1329,"end":1338},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T33","span":{"begin":1357,"end":1362},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T34","span":{"begin":1484,"end":1491},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T35","span":{"begin":1520,"end":1525},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T36","span":{"begin":1639,"end":1644},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T37","span":{"begin":1661,"end":1666},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T38","span":{"begin":1680,"end":1685},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T39","span":{"begin":1707,"end":1708},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T40","span":{"begin":1850,"end":1856},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T41","span":{"begin":1896,"end":1900},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T42","span":{"begin":1923,"end":1927},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T43","span":{"begin":1928,"end":1936},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T44","span":{"begin":1947,"end":1949},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T45","span":{"begin":1989,"end":1993},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T46","span":{"begin":1994,"end":2002},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T47","span":{"begin":2016,"end":2018},"obj":"http://purl.obolibrary.org/obo/CLO_0008922"},{"id":"T48","span":{"begin":2016,"end":2018},"obj":"http://purl.obolibrary.org/obo/CLO_0050052"},{"id":"T49","span":{"begin":2068,"end":2072},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T50","span":{"begin":2073,"end":2082},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T51","span":{"begin":2088,"end":2090},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T52","span":{"begin":2159,"end":2160},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T53","span":{"begin":2232,"end":2238},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T54","span":{"begin":2273,"end":2274},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T55","span":{"begin":2296,"end":2315},"obj":"http://purl.obolibrary.org/obo/CHEBI_33708"},{"id":"T56","span":{"begin":2296,"end":2315},"obj":"http://purl.obolibrary.org/obo/PR_000036907"},{"id":"T57","span":{"begin":2329,"end":2331},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T58","span":{"begin":2446,"end":2451},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T59","span":{"begin":2547,"end":2562},"obj":"http://purl.obolibrary.org/obo/CL_0000451"},{"id":"T60","span":{"begin":2564,"end":2566},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T61","span":{"begin":2575,"end":2580},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T62","span":{"begin":2575,"end":2580},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T63","span":{"begin":2634,"end":2637},"obj":"http://purl.obolibrary.org/obo/PR_000001004"},{"id":"T64","span":{"begin":2643,"end":2646},"obj":"http://purl.obolibrary.org/obo/CLO_0053438"},{"id":"T65","span":{"begin":2683,"end":2688},"obj":"http://purl.obolibrary.org/obo/CLO_0007225"},{"id":"T66","span":{"begin":2716,"end":2723},"obj":"http://purl.obolibrary.org/obo/CLO_0007225"},{"id":"T67","span":{"begin":2753,"end":2760},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T68","span":{"begin":2767,"end":2774},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T69","span":{"begin":2802,"end":2808},"obj":"http://purl.obolibrary.org/obo/CLO_0007225"},{"id":"T70","span":{"begin":2843,"end":2850},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T71","span":{"begin":2873,"end":2876},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T72","span":{"begin":3023,"end":3028},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T73","span":{"begin":3356,"end":3361},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T74","span":{"begin":3440,"end":3445},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T75","span":{"begin":3469,"end":3474},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T76","span":{"begin":3531,"end":3535},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T77","span":{"begin":3582,"end":3583},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T78","span":{"begin":3618,"end":3625},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T79","span":{"begin":3636,"end":3641},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"attributes":[{"subj":"T19","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T20","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T21","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T22","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T23","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T24","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T25","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T26","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T27","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T28","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T29","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T30","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T31","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T32","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T33","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T34","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T35","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T36","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T37","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T38","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T39","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T40","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T41","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T42","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T43","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T44","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T45","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T46","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T47","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T48","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T49","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T50","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T51","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T52","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T53","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T54","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T55","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T56","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T57","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T58","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T59","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T60","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T61","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T62","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T63","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T64","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T65","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T66","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T67","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T68","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T69","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T70","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T71","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T72","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T73","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T74","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T75","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T76","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T77","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T78","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T79","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T14","span":{"begin":214,"end":219},"obj":"Chemical"},{"id":"T15","span":{"begin":268,"end":276},"obj":"Chemical"},{"id":"T16","span":{"begin":291,"end":299},"obj":"Chemical"},{"id":"T17","span":{"begin":358,"end":366},"obj":"Chemical"},{"id":"T18","span":{"begin":380,"end":388},"obj":"Chemical"},{"id":"T19","span":{"begin":417,"end":426},"obj":"Chemical"},{"id":"T20","span":{"begin":530,"end":538},"obj":"Chemical"},{"id":"T21","span":{"begin":630,"end":638},"obj":"Chemical"},{"id":"T22","span":{"begin":790,"end":798},"obj":"Chemical"},{"id":"T23","span":{"begin":816,"end":829},"obj":"Chemical"},{"id":"T24","span":{"begin":831,"end":839},"obj":"Chemical"},{"id":"T25","span":{"begin":858,"end":872},"obj":"Chemical"},{"id":"T26","span":{"begin":876,"end":891},"obj":"Chemical"},{"id":"T27","span":{"begin":920,"end":927},"obj":"Chemical"},{"id":"T28","span":{"begin":941,"end":954},"obj":"Chemical"},{"id":"T29","span":{"begin":1041,"end":1046},"obj":"Chemical"},{"id":"T30","span":{"begin":1178,"end":1191},"obj":"Chemical"},{"id":"T31","span":{"begin":1303,"end":1311},"obj":"Chemical"},{"id":"T32","span":{"begin":1378,"end":1385},"obj":"Chemical"},{"id":"T33","span":{"begin":1465,"end":1473},"obj":"Chemical"},{"id":"T34","span":{"begin":1743,"end":1756},"obj":"Chemical"},{"id":"T35","span":{"begin":2016,"end":2018},"obj":"Chemical"},{"id":"T36","span":{"begin":2189,"end":2200},"obj":"Chemical"},{"id":"T37","span":{"begin":2296,"end":2306},"obj":"Chemical"},{"id":"T38","span":{"begin":2296,"end":2301},"obj":"Chemical"},{"id":"T39","span":{"begin":2302,"end":2306},"obj":"Chemical"},{"id":"T40","span":{"begin":2479,"end":2486},"obj":"Chemical"},{"id":"T41","span":{"begin":2512,"end":2519},"obj":"Chemical"},{"id":"T42","span":{"begin":2648,"end":2661},"obj":"Chemical"},{"id":"T43","span":{"begin":2669,"end":2682},"obj":"Chemical"},{"id":"T44","span":{"begin":2683,"end":2688},"obj":"Chemical"},{"id":"T45","span":{"begin":2699,"end":2706},"obj":"Chemical"},{"id":"T46","span":{"begin":2724,"end":2731},"obj":"Chemical"},{"id":"T47","span":{"begin":2828,"end":2835},"obj":"Chemical"},{"id":"T48","span":{"begin":2912,"end":2920},"obj":"Chemical"},{"id":"T49","span":{"begin":3121,"end":3129},"obj":"Chemical"},{"id":"T50","span":{"begin":3149,"end":3152},"obj":"Chemical"},{"id":"T51","span":{"begin":3227,"end":3236},"obj":"Chemical"},{"id":"T52","span":{"begin":3229,"end":3236},"obj":"Chemical"},{"id":"T53","span":{"begin":3484,"end":3492},"obj":"Chemical"}],"attributes":[{"id":"A14","pred":"chebi_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_18059"},{"id":"A15","pred":"chebi_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A16","pred":"chebi_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A17","pred":"chebi_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A18","pred":"chebi_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A19","pred":"chebi_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A20","pred":"chebi_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A21","pred":"chebi_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A22","pred":"chebi_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A23","pred":"chebi_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/CHEBI_17089"},{"id":"A24","pred":"chebi_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A25","pred":"chebi_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/CHEBI_18154"},{"id":"A26","pred":"chebi_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/CHEBI_50699"},{"id":"A27","pred":"chebi_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/CHEBI_18154"},{"id":"A28","pred":"chebi_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/CHEBI_17089"},{"id":"A29","pred":"chebi_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/CHEBI_15377"},{"id":"A30","pred":"chebi_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/CHEBI_17089"},{"id":"A31","pred":"chebi_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A32","pred":"chebi_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/CHEBI_18154"},{"id":"A33","pred":"chebi_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A34","pred":"chebi_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/CHEBI_17089"},{"id":"A35","pred":"chebi_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/CHEBI_29387"},{"id":"A36","pred":"chebi_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A37","pred":"chebi_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/CHEBI_33709"},{"id":"A38","pred":"chebi_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A39","pred":"chebi_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A40","pred":"chebi_id","subj":"T40","obj":"http://purl.obolibrary.org/obo/CHEBI_18154"},{"id":"A41","pred":"chebi_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A42","pred":"chebi_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/CHEBI_24396"},{"id":"A43","pred":"chebi_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/CHEBI_24396"},{"id":"A44","pred":"chebi_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/CHEBI_35209"},{"id":"A45","pred":"chebi_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A46","pred":"chebi_id","subj":"T46","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A47","pred":"chebi_id","subj":"T47","obj":"http://purl.obolibrary.org/obo/CHEBI_59132"},{"id":"A48","pred":"chebi_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A49","pred":"chebi_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/CHEBI_59132"},{"id":"A50","pred":"chebi_id","subj":"T50","obj":"http://purl.obolibrary.org/obo/CHEBI_48015"},{"id":"A51","pred":"chebi_id","subj":"T51","obj":"http://purl.obolibrary.org/obo/CHEBI_59520"},{"id":"A52","pred":"chebi_id","subj":"T52","obj":"http://purl.obolibrary.org/obo/CHEBI_18154"},{"id":"A53","pred":"chebi_id","subj":"T53","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"subj":"T14","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T15","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T16","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T17","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T18","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T19","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T20","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T21","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T22","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T23","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T24","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T25","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T26","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T27","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T28","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T29","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T30","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T31","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T32","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T33","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T34","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T35","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T36","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T37","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T38","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T39","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T40","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T41","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T42","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T43","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T44","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T45","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T46","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T47","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T48","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T49","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T50","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T51","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T52","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T53","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T1","span":{"begin":473,"end":486},"obj":"http://purl.obolibrary.org/obo/GO_0006493"},{"id":"T2","span":{"begin":657,"end":672},"obj":"http://purl.obolibrary.org/obo/GO_0044409"},{"id":"T3","span":{"begin":1639,"end":1666},"obj":"http://purl.obolibrary.org/obo/GO_0046718"},{"id":"T4","span":{"begin":1645,"end":1660},"obj":"http://purl.obolibrary.org/obo/GO_0044409"},{"id":"T5","span":{"begin":2457,"end":2473},"obj":"http://purl.obolibrary.org/obo/GO_0006955"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T2","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T3","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T4","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T5","pred":"source","obj":"LitCovid-PD-GO-BP"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"40","span":{"begin":784,"end":789},"obj":"Gene"},{"id":"41","span":{"begin":624,"end":629},"obj":"Gene"},{"id":"42","span":{"begin":85,"end":93},"obj":"Species"},{"id":"43","span":{"begin":98,"end":108},"obj":"Species"},{"id":"44","span":{"begin":713,"end":726},"obj":"Species"},{"id":"45","span":{"begin":348,"end":353},"obj":"Gene"},{"id":"46","span":{"begin":411,"end":416},"obj":"Chemical"},{"id":"47","span":{"begin":449,"end":455},"obj":"Chemical"},{"id":"48","span":{"begin":467,"end":486},"obj":"Chemical"},{"id":"49","span":{"begin":858,"end":872},"obj":"Chemical"},{"id":"50","span":{"begin":876,"end":891},"obj":"Chemical"},{"id":"51","span":{"begin":920,"end":927},"obj":"Chemical"},{"id":"55","span":{"begin":1041,"end":1046},"obj":"Chemical"},{"id":"56","span":{"begin":1288,"end":1294},"obj":"Chemical"},{"id":"57","span":{"begin":1378,"end":1385},"obj":"Chemical"},{"id":"65","span":{"begin":2189,"end":2220},"obj":"Gene"},{"id":"66","span":{"begin":2222,"end":2227},"obj":"Gene"},{"id":"67","span":{"begin":1760,"end":1770},"obj":"Species"},{"id":"68","span":{"begin":2129,"end":2142},"obj":"Species"},{"id":"69","span":{"begin":2232,"end":2238},"obj":"Species"},{"id":"70","span":{"begin":2380,"end":2393},"obj":"Species"},{"id":"71","span":{"begin":1737,"end":1742},"obj":"Gene"},{"id":"88","span":{"begin":2693,"end":2698},"obj":"Gene"},{"id":"89","span":{"begin":2506,"end":2511},"obj":"Gene"},{"id":"90","span":{"begin":2446,"end":2451},"obj":"Species"},{"id":"91","span":{"begin":2494,"end":2505},"obj":"Species"},{"id":"92","span":{"begin":3002,"end":3007},"obj":"Species"},{"id":"93","span":{"begin":3009,"end":3017},"obj":"Species"},{"id":"94","span":{"begin":3023,"end":3044},"obj":"Species"},{"id":"95","span":{"begin":3154,"end":3171},"obj":"Species"},{"id":"96","span":{"begin":3545,"end":3558},"obj":"Species"},{"id":"97","span":{"begin":2479,"end":2486},"obj":"Chemical"},{"id":"98","span":{"begin":2600,"end":2606},"obj":"Chemical"},{"id":"99","span":{"begin":2648,"end":2661},"obj":"Chemical"},{"id":"100","span":{"begin":2669,"end":2682},"obj":"Chemical"},{"id":"101","span":{"begin":2897,"end":2903},"obj":"Chemical"},{"id":"102","span":{"begin":3227,"end":3236},"obj":"Chemical"},{"id":"103","span":{"begin":3344,"end":3350},"obj":"Chemical"}],"attributes":[{"id":"A40","pred":"tao:has_database_id","subj":"40","obj":"Gene:43740568"},{"id":"A41","pred":"tao:has_database_id","subj":"41","obj":"Gene:43740568"},{"id":"A42","pred":"tao:has_database_id","subj":"42","obj":"Tax:694009"},{"id":"A43","pred":"tao:has_database_id","subj":"43","obj":"Tax:2697049"},{"id":"A44","pred":"tao:has_database_id","subj":"44","obj":"Tax:11118"},{"id":"A45","pred":"tao:has_database_id","subj":"45","obj":"Gene:43740568"},{"id":"A46","pred":"tao:has_database_id","subj":"46","obj":"MESH:D000073893"},{"id":"A47","pred":"tao:has_database_id","subj":"47","obj":"MESH:D011134"},{"id":"A49","pred":"tao:has_database_id","subj":"49","obj":"MESH:D011134"},{"id":"A50","pred":"tao:has_database_id","subj":"50","obj":"MESH:D009844"},{"id":"A51","pred":"tao:has_database_id","subj":"51","obj":"MESH:D011134"},{"id":"A55","pred":"tao:has_database_id","subj":"55","obj":"MESH:D014867"},{"id":"A56","pred":"tao:has_database_id","subj":"56","obj":"MESH:D011134"},{"id":"A57","pred":"tao:has_database_id","subj":"57","obj":"MESH:D011134"},{"id":"A65","pred":"tao:has_database_id","subj":"65","obj":"Gene:59272"},{"id":"A66","pred":"tao:has_database_id","subj":"66","obj":"Gene:59272"},{"id":"A67","pred":"tao:has_database_id","subj":"67","obj":"Tax:2697049"},{"id":"A68","pred":"tao:has_database_id","subj":"68","obj":"Tax:11118"},{"id":"A69","pred":"tao:has_database_id","subj":"69","obj":"Tax:9606"},{"id":"A70","pred":"tao:has_database_id","subj":"70","obj":"Tax:11118"},{"id":"A71","pred":"tao:has_database_id","subj":"71","obj":"Gene:43740568"},{"id":"A88","pred":"tao:has_database_id","subj":"88","obj":"Gene:43740568"},{"id":"A89","pred":"tao:has_database_id","subj":"89","obj":"Gene:43740568"},{"id":"A90","pred":"tao:has_database_id","subj":"90","obj":"Tax:9606"},{"id":"A91","pred":"tao:has_database_id","subj":"91","obj":"Tax:11118"},{"id":"A92","pred":"tao:has_database_id","subj":"92","obj":"Tax:11676"},{"id":"A93","pred":"tao:has_database_id","subj":"93","obj":"Tax:694009"},{"id":"A94","pred":"tao:has_database_id","subj":"94","obj":"Tax:10359"},{"id":"A95","pred":"tao:has_database_id","subj":"95","obj":"Tax:4670"},{"id":"A96","pred":"tao:has_database_id","subj":"96","obj":"Tax:11118"},{"id":"A97","pred":"tao:has_database_id","subj":"97","obj":"MESH:D011134"},{"id":"A98","pred":"tao:has_database_id","subj":"98","obj":"MESH:D011134"},{"id":"A99","pred":"tao:has_database_id","subj":"99","obj":"MESH:D006020"},{"id":"A100","pred":"tao:has_database_id","subj":"100","obj":"MESH:D006020"},{"id":"A101","pred":"tao:has_database_id","subj":"101","obj":"MESH:D011134"},{"id":"A103","pred":"tao:has_database_id","subj":"103","obj":"MESH:D011134"},{"subj":"40","pred":"source","obj":"LitCovid-PubTator"},{"subj":"41","pred":"source","obj":"LitCovid-PubTator"},{"subj":"42","pred":"source","obj":"LitCovid-PubTator"},{"subj":"43","pred":"source","obj":"LitCovid-PubTator"},{"subj":"44","pred":"source","obj":"LitCovid-PubTator"},{"subj":"45","pred":"source","obj":"LitCovid-PubTator"},{"subj":"46","pred":"source","obj":"LitCovid-PubTator"},{"subj":"47","pred":"source","obj":"LitCovid-PubTator"},{"subj":"48","pred":"source","obj":"LitCovid-PubTator"},{"subj":"49","pred":"source","obj":"LitCovid-PubTator"},{"subj":"50","pred":"source","obj":"LitCovid-PubTator"},{"subj":"51","pred":"source","obj":"LitCovid-PubTator"},{"subj":"55","pred":"source","obj":"LitCovid-PubTator"},{"subj":"56","pred":"source","obj":"LitCovid-PubTator"},{"subj":"57","pred":"source","obj":"LitCovid-PubTator"},{"subj":"65","pred":"source","obj":"LitCovid-PubTator"},{"subj":"66","pred":"source","obj":"LitCovid-PubTator"},{"subj":"67","pred":"source","obj":"LitCovid-PubTator"},{"subj":"68","pred":"source","obj":"LitCovid-PubTator"},{"subj":"69","pred":"source","obj":"LitCovid-PubTator"},{"subj":"70","pred":"source","obj":"LitCovid-PubTator"},{"subj":"71","pred":"source","obj":"LitCovid-PubTator"},{"subj":"88","pred":"source","obj":"LitCovid-PubTator"},{"subj":"89","pred":"source","obj":"LitCovid-PubTator"},{"subj":"90","pred":"source","obj":"LitCovid-PubTator"},{"subj":"91","pred":"source","obj":"LitCovid-PubTator"},{"subj":"92","pred":"source","obj":"LitCovid-PubTator"},{"subj":"93","pred":"source","obj":"LitCovid-PubTator"},{"subj":"94","pred":"source","obj":"LitCovid-PubTator"},{"subj":"95","pred":"source","obj":"LitCovid-PubTator"},{"subj":"96","pred":"source","obj":"LitCovid-PubTator"},{"subj":"97","pred":"source","obj":"LitCovid-PubTator"},{"subj":"98","pred":"source","obj":"LitCovid-PubTator"},{"subj":"99","pred":"source","obj":"LitCovid-PubTator"},{"subj":"100","pred":"source","obj":"LitCovid-PubTator"},{"subj":"101","pred":"source","obj":"LitCovid-PubTator"},{"subj":"102","pred":"source","obj":"LitCovid-PubTator"},{"subj":"103","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T23","span":{"begin":0,"end":2},"obj":"Sentence"},{"id":"T24","span":{"begin":3,"end":51},"obj":"Sentence"},{"id":"T25","span":{"begin":52,"end":163},"obj":"Sentence"},{"id":"T26","span":{"begin":164,"end":371},"obj":"Sentence"},{"id":"T27","span":{"begin":372,"end":466},"obj":"Sentence"},{"id":"T28","span":{"begin":467,"end":617},"obj":"Sentence"},{"id":"T29","span":{"begin":618,"end":679},"obj":"Sentence"},{"id":"T30","span":{"begin":680,"end":783},"obj":"Sentence"},{"id":"T31","span":{"begin":784,"end":936},"obj":"Sentence"},{"id":"T32","span":{"begin":937,"end":1133},"obj":"Sentence"},{"id":"T33","span":{"begin":1134,"end":1367},"obj":"Sentence"},{"id":"T34","span":{"begin":1368,"end":1474},"obj":"Sentence"},{"id":"T35","span":{"begin":1475,"end":1549},"obj":"Sentence"},{"id":"T36","span":{"begin":1550,"end":1706},"obj":"Sentence"},{"id":"T37","span":{"begin":1707,"end":1827},"obj":"Sentence"},{"id":"T38","span":{"begin":1828,"end":1937},"obj":"Sentence"},{"id":"T39","span":{"begin":1938,"end":2083},"obj":"Sentence"},{"id":"T40","span":{"begin":2084,"end":2178},"obj":"Sentence"},{"id":"T41","span":{"begin":2179,"end":2430},"obj":"Sentence"},{"id":"T42","span":{"begin":2431,"end":2662},"obj":"Sentence"},{"id":"T43","span":{"begin":2663,"end":2766},"obj":"Sentence"},{"id":"T44","span":{"begin":2767,"end":2869},"obj":"Sentence"},{"id":"T45","span":{"begin":2870,"end":3045},"obj":"Sentence"},{"id":"T46","span":{"begin":3046,"end":3184},"obj":"Sentence"},{"id":"T47","span":{"begin":3185,"end":3314},"obj":"Sentence"},{"id":"T48","span":{"begin":3315,"end":3481},"obj":"Sentence"},{"id":"T49","span":{"begin":3482,"end":3564},"obj":"Sentence"},{"id":"T50","span":{"begin":3565,"end":3642},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T23","pred":"source","obj":"LitCovid-sentences"},{"subj":"T24","pred":"source","obj":"LitCovid-sentences"},{"subj":"T25","pred":"source","obj":"LitCovid-sentences"},{"subj":"T26","pred":"source","obj":"LitCovid-sentences"},{"subj":"T27","pred":"source","obj":"LitCovid-sentences"},{"subj":"T28","pred":"source","obj":"LitCovid-sentences"},{"subj":"T29","pred":"source","obj":"LitCovid-sentences"},{"subj":"T30","pred":"source","obj":"LitCovid-sentences"},{"subj":"T31","pred":"source","obj":"LitCovid-sentences"},{"subj":"T32","pred":"source","obj":"LitCovid-sentences"},{"subj":"T33","pred":"source","obj":"LitCovid-sentences"},{"subj":"T34","pred":"source","obj":"LitCovid-sentences"},{"subj":"T35","pred":"source","obj":"LitCovid-sentences"},{"subj":"T36","pred":"source","obj":"LitCovid-sentences"},{"subj":"T37","pred":"source","obj":"LitCovid-sentences"},{"subj":"T38","pred":"source","obj":"LitCovid-sentences"},{"subj":"T39","pred":"source","obj":"LitCovid-sentences"},{"subj":"T40","pred":"source","obj":"LitCovid-sentences"},{"subj":"T41","pred":"source","obj":"LitCovid-sentences"},{"subj":"T42","pred":"source","obj":"LitCovid-sentences"},{"subj":"T43","pred":"source","obj":"LitCovid-sentences"},{"subj":"T44","pred":"source","obj":"LitCovid-sentences"},{"subj":"T45","pred":"source","obj":"LitCovid-sentences"},{"subj":"T46","pred":"source","obj":"LitCovid-sentences"},{"subj":"T47","pred":"source","obj":"LitCovid-sentences"},{"subj":"T48","pred":"source","obj":"LitCovid-sentences"},{"subj":"T49","pred":"source","obj":"LitCovid-sentences"},{"subj":"T50","pred":"source","obj":"LitCovid-sentences"}]},{"project":"2_test","denotations":[{"id":"32731428-26925438-71421239","span":{"begin":368,"end":369},"obj":"26925438"},{"id":"32731428-10799570-71421240","span":{"begin":612,"end":613},"obj":"10799570"},{"id":"32731428-24736006-71421241","span":{"begin":614,"end":615},"obj":"24736006"},{"id":"32731428-24188132-71421242","span":{"begin":929,"end":930},"obj":"24188132"},{"id":"32731428-27558841-71421243","span":{"begin":931,"end":932},"obj":"27558841"},{"id":"32731428-31121217-71421244","span":{"begin":933,"end":934},"obj":"31121217"},{"id":"32731428-27558841-71421245","span":{"begin":1130,"end":1131},"obj":"27558841"},{"id":"32731428-26925438-71421246","span":{"begin":1364,"end":1365},"obj":"26925438"},{"id":"32731428-31121217-71421247","span":{"begin":1703,"end":1704},"obj":"31121217"},{"id":"32731428-32155444-71421248","span":{"begin":2175,"end":2176},"obj":"32155444"},{"id":"32731428-14651994-71421249","span":{"begin":2317,"end":2318},"obj":"14651994"},{"id":"32731428-18931070-71421250","span":{"begin":2426,"end":2428},"obj":"18931070"},{"id":"32731428-18799140-71421251","span":{"begin":2564,"end":2566},"obj":"18799140"},{"id":"32731428-32328406-71421252","span":{"begin":2762,"end":2764},"obj":"32328406"},{"id":"32731428-24188132-71421253","span":{"begin":2945,"end":2946},"obj":"24188132"},{"id":"32731428-25774492-71421254","span":{"begin":3310,"end":3312},"obj":"25774492"},{"id":"32731428-16258152-71421255","span":{"begin":3560,"end":3562},"obj":"16258152"}],"attributes":[{"subj":"32731428-26925438-71421239","pred":"source","obj":"2_test"},{"subj":"32731428-10799570-71421240","pred":"source","obj":"2_test"},{"subj":"32731428-24736006-71421241","pred":"source","obj":"2_test"},{"subj":"32731428-24188132-71421242","pred":"source","obj":"2_test"},{"subj":"32731428-27558841-71421243","pred":"source","obj":"2_test"},{"subj":"32731428-31121217-71421244","pred":"source","obj":"2_test"},{"subj":"32731428-27558841-71421245","pred":"source","obj":"2_test"},{"subj":"32731428-26925438-71421246","pred":"source","obj":"2_test"},{"subj":"32731428-31121217-71421247","pred":"source","obj":"2_test"},{"subj":"32731428-32155444-71421248","pred":"source","obj":"2_test"},{"subj":"32731428-14651994-71421249","pred":"source","obj":"2_test"},{"subj":"32731428-18931070-71421250","pred":"source","obj":"2_test"},{"subj":"32731428-18799140-71421251","pred":"source","obj":"2_test"},{"subj":"32731428-32328406-71421252","pred":"source","obj":"2_test"},{"subj":"32731428-24188132-71421253","pred":"source","obj":"2_test"},{"subj":"32731428-25774492-71421254","pred":"source","obj":"2_test"},{"subj":"32731428-16258152-71421255","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#93ec9b","default":true},{"id":"LitCovid-PD-UBERON","color":"#ec93a5"},{"id":"LitCovid-PD-MONDO","color":"#93bfec"},{"id":"LitCovid-PD-CLO","color":"#d9ec93"},{"id":"LitCovid-PD-CHEBI","color":"#e593ec"},{"id":"LitCovid-PD-GO-BP","color":"#93eccb"},{"id":"LitCovid-PubTator","color":"#ecb193"},{"id":"LitCovid-sentences","color":"#9793ec"},{"id":"2_test","color":"#a9ec93"}]}]}}