PMC:7426526 / 29949-30588
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7426526","sourcedb":"PMC","sourceid":"7426526","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7426526","text":"Nanog is a homeobox domain transcription factor widely expressed in human cancers (487). In colorectal tumors its expression was significantly increased in CD133+ cells, and on the basis of a univariate analysis, Nanog expression correlated linearly to liver and lymph node metastasis and the TNM stage. It might therefore be useful as a prognostic biomarker in post-operative liver metastasis (362). In breast cancer, expression of Nanog and Oct-3/4 has been correlated to a poor prognosis of the patient as well as EMT (220, 221). In HCC cell lines Nanog expression drives selfrenewal and invasion, metastasis, and drug resistance (298).","tracks":[{"project":"TEST0","denotations":[{"id":"32849491-83-90-3396367","span":{"begin":83,"end":86},"obj":"[\"25821200\"]"},{"id":"32849491-91-98-3396368","span":{"begin":395,"end":398},"obj":"[\"22562535\"]"},{"id":"32849491-121-128-3396369","span":{"begin":522,"end":525},"obj":"[\"25301732\"]"},{"id":"32849491-126-133-3396370","span":{"begin":527,"end":530},"obj":"[\"30464534\"]"},{"id":"32849491-101-108-3396371","span":{"begin":634,"end":637},"obj":"[\"27610139\"]"}],"attributes":[{"subj":"32849491-83-90-3396367","pred":"source","obj":"TEST0"},{"subj":"32849491-91-98-3396368","pred":"source","obj":"TEST0"},{"subj":"32849491-121-128-3396369","pred":"source","obj":"TEST0"},{"subj":"32849491-126-133-3396370","pred":"source","obj":"TEST0"},{"subj":"32849491-101-108-3396371","pred":"source","obj":"TEST0"}]},{"project":"MyTest","denotations":[{"id":"32849491-25821200-34970747","span":{"begin":83,"end":86},"obj":"25821200"},{"id":"32849491-22562535-34970748","span":{"begin":395,"end":398},"obj":"22562535"},{"id":"32849491-25301732-34970749","span":{"begin":522,"end":525},"obj":"25301732"},{"id":"32849491-30464534-34970750","span":{"begin":527,"end":530},"obj":"30464534"},{"id":"32849491-27610139-34970751","span":{"begin":634,"end":637},"obj":"27610139"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"attributes":[{"subj":"32849491-25821200-34970747","pred":"source","obj":"MyTest"},{"subj":"32849491-22562535-34970748","pred":"source","obj":"MyTest"},{"subj":"32849491-25301732-34970749","pred":"source","obj":"MyTest"},{"subj":"32849491-30464534-34970750","pred":"source","obj":"MyTest"},{"subj":"32849491-27610139-34970751","pred":"source","obj":"MyTest"}]},{"project":"2_test","denotations":[{"id":"32849491-25821200-34970747","span":{"begin":83,"end":86},"obj":"25821200"},{"id":"32849491-22562535-34970748","span":{"begin":395,"end":398},"obj":"22562535"},{"id":"32849491-25301732-34970749","span":{"begin":522,"end":525},"obj":"25301732"},{"id":"32849491-30464534-34970750","span":{"begin":527,"end":530},"obj":"30464534"},{"id":"32849491-27610139-34970751","span":{"begin":634,"end":637},"obj":"27610139"}],"attributes":[{"subj":"32849491-25821200-34970747","pred":"source","obj":"2_test"},{"subj":"32849491-22562535-34970748","pred":"source","obj":"2_test"},{"subj":"32849491-25301732-34970749","pred":"source","obj":"2_test"},{"subj":"32849491-30464534-34970750","pred":"source","obj":"2_test"},{"subj":"32849491-27610139-34970751","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"TEST0","color":"#d893ec","default":true},{"id":"MyTest","color":"#93ecbe"},{"id":"2_test","color":"#eca493"}]}]}}