PMC:7426526 / 16027-17479 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7426526","sourcedb":"PMC","sourceid":"7426526","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7426526","text":"Table 3 Examples of gastric cancer stem cell markers and their use as diagnostic, predictive, or therapeutic biomarkers.\nMarker Stem cell marker Biomarker diagnostic Biomarker therapeutic Biomarker prognostic\nSurface markers, CD\nCD24 (238) (239)* (240)* (241) (242–244) (239, 245)*\nCD44 (and its variants) (246–251) (239, 240, 245, 252)* (247, 251, 253, 254) (240)* (255–257) (239, 240, 245)* (247, 251, 254, 258–260) (239, 240, 245, 252)*\nCD90 (251) (239, 245)*\nCD133 (247, 249, 250) (239, 240, 252)* (254, 261) (240)* (257) (239, 240)* (254, 262–265) (239, 240, 252)*\nSurface markers, no CD\nCXCR4 (266) (267)* (268–271)\nEpCAM (248, 249, 272) (239, 240, 252)* (273) (265, 272)\nLGR5 (274) (252)* (240)* (275, 276) (252)* (275, 277–279)\nLINGO2 (280) (280)\nIntracellular markers\nALDH (249, 281, 282) (239, 240, 252)* (260, 281, 282)\nLetm1 (283) (283)\nMusashi2 (284) (284)\nNanog (285) (239, 286)* (287) (240)* (287, 288) (286)*\nOct-3/4 (239, 252)* (289)** (247, 265, 288) (289)**\nSox2 (247) (239, 240, 252, 290)* (240)* (291)** (292) (247, 288, 293) (265)**\nThe table lists examples of cancer stem cell markers and indicates those which have been tested as biomarkers within a therapeutic (metastasis, tumor stage, size, resistance), diagnostic (i.e., resistance), or prognostic (survival, resistance etc.) approach. 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