PMC:7417788 / 52378-52755 JSONTXT

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{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T382","span":{"begin":94,"end":99},"obj":"Body_part"},{"id":"T383","span":{"begin":122,"end":127},"obj":"Body_part"},{"id":"T384","span":{"begin":132,"end":139},"obj":"Body_part"},{"id":"T385","span":{"begin":152,"end":174},"obj":"Body_part"},{"id":"T386","span":{"begin":198,"end":209},"obj":"Body_part"},{"id":"T387","span":{"begin":213,"end":218},"obj":"Body_part"},{"id":"T388","span":{"begin":282,"end":288},"obj":"Body_part"},{"id":"T389","span":{"begin":316,"end":340},"obj":"Body_part"},{"id":"T390","span":{"begin":335,"end":340},"obj":"Body_part"},{"id":"T391","span":{"begin":344,"end":355},"obj":"Body_part"}],"attributes":[{"id":"A382","pred":"fma_id","subj":"T382","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A383","pred":"fma_id","subj":"T383","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A384","pred":"fma_id","subj":"T384","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A385","pred":"fma_id","subj":"T385","obj":"http://purl.org/sig/ont/fma/fma55675"},{"id":"A386","pred":"fma_id","subj":"T386","obj":"http://purl.org/sig/ont/fma/fma63261"},{"id":"A387","pred":"fma_id","subj":"T387","obj":"http://purl.org/sig/ont/fma/fma50801"},{"id":"A388","pred":"fma_id","subj":"T388","obj":"http://purl.org/sig/ont/fma/fma7196"},{"id":"A389","pred":"fma_id","subj":"T389","obj":"http://purl.org/sig/ont/fma/fma86475"},{"id":"A390","pred":"fma_id","subj":"T390","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A391","pred":"fma_id","subj":"T391","obj":"http://purl.org/sig/ont/fma/fma9608"}],"text":"Using scRNA-seq, recent studies have reported transcriptomic and functional changes in immune cells during aging in mouse cells and tissues such as the central nervous system (Mrdjen et al., 2018), macrophages in brain (Martinez-Jimenez et al., 2017; Van Hove et al., 2019), TCs in spleen (Dulken et al., 2019), and hematopoietic stem cells in bone marrow (Leins et al., 2018)."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T23","span":{"begin":152,"end":174},"obj":"Body_part"},{"id":"T24","span":{"begin":160,"end":174},"obj":"Body_part"},{"id":"T25","span":{"begin":213,"end":218},"obj":"Body_part"},{"id":"T26","span":{"begin":282,"end":288},"obj":"Body_part"},{"id":"T27","span":{"begin":344,"end":355},"obj":"Body_part"}],"attributes":[{"id":"A23","pred":"uberon_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/UBERON_0001017"},{"id":"A24","pred":"uberon_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/UBERON_0001016"},{"id":"A25","pred":"uberon_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/UBERON_0000955"},{"id":"A26","pred":"uberon_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/UBERON_0002106"},{"id":"A27","pred":"uberon_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/UBERON_0002371"}],"text":"Using scRNA-seq, recent studies have reported transcriptomic and functional changes in immune cells during aging in mouse cells and tissues such as the central nervous system (Mrdjen et al., 2018), macrophages in brain (Martinez-Jimenez et al., 2017; Van Hove et al., 2019), TCs in spleen (Dulken et al., 2019), and hematopoietic stem cells in bone marrow (Leins et al., 2018)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T933","span":{"begin":94,"end":99},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T934","span":{"begin":116,"end":121},"obj":"http://purl.obolibrary.org/obo/CLO_0007836"},{"id":"T935","span":{"begin":122,"end":127},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T936","span":{"begin":152,"end":174},"obj":"http://purl.obolibrary.org/obo/UBERON_0001017"},{"id":"T937","span":{"begin":152,"end":174},"obj":"http://www.ebi.ac.uk/efo/EFO_0000302"},{"id":"T938","span":{"begin":152,"end":174},"obj":"http://www.ebi.ac.uk/efo/EFO_0000908"},{"id":"T939","span":{"begin":191,"end":195},"obj":"http://purl.obolibrary.org/obo/CLO_0001185"},{"id":"T940","span":{"begin":213,"end":218},"obj":"http://purl.obolibrary.org/obo/UBERON_0000955"},{"id":"T941","span":{"begin":213,"end":218},"obj":"http://www.ebi.ac.uk/efo/EFO_0000302"},{"id":"T942","span":{"begin":275,"end":278},"obj":"http://purl.obolibrary.org/obo/CLO_0050938"},{"id":"T943","span":{"begin":275,"end":278},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T944","span":{"begin":282,"end":288},"obj":"http://purl.obolibrary.org/obo/UBERON_0002106"},{"id":"T945","span":{"begin":330,"end":340},"obj":"http://purl.obolibrary.org/obo/CL_0000034"},{"id":"T946","span":{"begin":344,"end":348},"obj":"http://purl.obolibrary.org/obo/UBERON_0002481"},{"id":"T947","span":{"begin":371,"end":375},"obj":"http://purl.obolibrary.org/obo/CLO_0001185"}],"text":"Using scRNA-seq, recent studies have reported transcriptomic and functional changes in immune cells during aging in mouse cells and tissues such as the central nervous system (Mrdjen et al., 2018), macrophages in brain (Martinez-Jimenez et al., 2017; Van Hove et al., 2019), TCs in spleen (Dulken et al., 2019), and hematopoietic stem cells in bone marrow (Leins et al., 2018)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T249","span":{"begin":107,"end":112},"obj":"http://purl.obolibrary.org/obo/GO_0007568"}],"text":"Using scRNA-seq, recent studies have reported transcriptomic and functional changes in immune cells during aging in mouse cells and tissues such as the central nervous system (Mrdjen et al., 2018), macrophages in brain (Martinez-Jimenez et al., 2017; Van Hove et al., 2019), TCs in spleen (Dulken et al., 2019), and hematopoietic stem cells in bone marrow (Leins et al., 2018)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T266","span":{"begin":0,"end":377},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Using scRNA-seq, recent studies have reported transcriptomic and functional changes in immune cells during aging in mouse cells and tissues such as the central nervous system (Mrdjen et al., 2018), macrophages in brain (Martinez-Jimenez et al., 2017; Van Hove et al., 2019), TCs in spleen (Dulken et al., 2019), and hematopoietic stem cells in bone marrow (Leins et al., 2018)."}

{"project":"2_test","denotations":[{"id":"32780218-29706550-132718713","span":{"begin":191,"end":195},"obj":"29706550"},{"id":"32780218-29891535-132718714","span":{"begin":245,"end":249},"obj":"29891535"},{"id":"32780218-29891535-132718715","span":{"begin":268,"end":272},"obj":"29891535"},{"id":"32780218-29706550-132718716","span":{"begin":305,"end":309},"obj":"29706550"},{"id":"32780218-29891535-132718717","span":{"begin":371,"end":375},"obj":"29891535"}],"text":"Using scRNA-seq, recent studies have reported transcriptomic and functional changes in immune cells during aging in mouse cells and tissues such as the central nervous system (Mrdjen et al., 2018), macrophages in brain (Martinez-Jimenez et al., 2017; Van Hove et al., 2019), TCs in spleen (Dulken et al., 2019), and hematopoietic stem cells in bone marrow (Leins et al., 2018)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1172","span":{"begin":116,"end":121},"obj":"Species"}],"attributes":[{"id":"A1172","pred":"tao:has_database_id","subj":"1172","obj":"Tax:10090"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Using scRNA-seq, recent studies have reported transcriptomic and functional changes in immune cells during aging in mouse cells and tissues such as the central nervous system (Mrdjen et al., 2018), macrophages in brain (Martinez-Jimenez et al., 2017; Van Hove et al., 2019), TCs in spleen (Dulken et al., 2019), and hematopoietic stem cells in bone marrow (Leins et al., 2018)."}