PMC:7417788 / 33765-34051 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T778","span":{"begin":13,"end":20},"obj":"CHEBI:59132;CHEBI:59132"},{"id":"T779","span":{"begin":42,"end":56},"obj":"GO:0019814"},{"id":"T780","span":{"begin":183,"end":188},"obj":"GO:0007568"}],"text":"Although the antigen repertoire sensed by immunoglobulin receptors on both TCs (TCRs) and BCs (BCRs) is known to continuously evolve with age (Yuseff et al., 2013), the phenomenon of aging-associated TCR and BCR repertoire constriction has not yet been studied at the single-cell level."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T295","span":{"begin":42,"end":56},"obj":"Body_part"},{"id":"T296","span":{"begin":275,"end":279},"obj":"Body_part"}],"attributes":[{"id":"A295","pred":"fma_id","subj":"T295","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A296","pred":"fma_id","subj":"T296","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"Although the antigen repertoire sensed by immunoglobulin receptors on both TCs (TCRs) and BCs (BCRs) is known to continuously evolve with age (Yuseff et al., 2013), the phenomenon of aging-associated TCR and BCR repertoire constriction has not yet been studied at the single-cell level."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T641","span":{"begin":75,"end":78},"obj":"http://purl.obolibrary.org/obo/CLO_0050938"},{"id":"T642","span":{"begin":75,"end":78},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T643","span":{"begin":90,"end":93},"obj":"http://purl.obolibrary.org/obo/CL_0000236"},{"id":"T644","span":{"begin":236,"end":239},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T645","span":{"begin":275,"end":279},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"Although the antigen repertoire sensed by immunoglobulin receptors on both TCs (TCRs) and BCs (BCRs) is known to continuously evolve with age (Yuseff et al., 2013), the phenomenon of aging-associated TCR and BCR repertoire constriction has not yet been studied at the single-cell level."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T246","span":{"begin":13,"end":20},"obj":"Chemical"}],"attributes":[{"id":"A246","pred":"chebi_id","subj":"T246","obj":"http://purl.obolibrary.org/obo/CHEBI_59132"}],"text":"Although the antigen repertoire sensed by immunoglobulin receptors on both TCs (TCRs) and BCs (BCRs) is known to continuously evolve with age (Yuseff et al., 2013), the phenomenon of aging-associated TCR and BCR repertoire constriction has not yet been studied at the single-cell level."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T187","span":{"begin":183,"end":188},"obj":"http://purl.obolibrary.org/obo/GO_0007568"}],"text":"Although the antigen repertoire sensed by immunoglobulin receptors on both TCs (TCRs) and BCs (BCRs) is known to continuously evolve with age (Yuseff et al., 2013), the phenomenon of aging-associated TCR and BCR repertoire constriction has not yet been studied at the single-cell level."}

{"project":"LitCovid-sentences","denotations":[{"id":"T176","span":{"begin":0,"end":286},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Although the antigen repertoire sensed by immunoglobulin receptors on both TCs (TCRs) and BCs (BCRs) is known to continuously evolve with age (Yuseff et al., 2013), the phenomenon of aging-associated TCR and BCR repertoire constriction has not yet been studied at the single-cell level."}

{"project":"2_test","denotations":[{"id":"32780218-29891535-132718702","span":{"begin":158,"end":162},"obj":"29891535"}],"text":"Although the antigen repertoire sensed by immunoglobulin receptors on both TCs (TCRs) and BCs (BCRs) is known to continuously evolve with age (Yuseff et al., 2013), the phenomenon of aging-associated TCR and BCR repertoire constriction has not yet been studied at the single-cell level."}

{"project":"LitCovid-PubTator","denotations":[{"id":"771","span":{"begin":208,"end":211},"obj":"Gene"},{"id":"785","span":{"begin":200,"end":203},"obj":"Gene"}],"attributes":[{"id":"A771","pred":"tao:has_database_id","subj":"771","obj":"Gene:613"},{"id":"A785","pred":"tao:has_database_id","subj":"785","obj":"Gene:6962"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Although the antigen repertoire sensed by immunoglobulin receptors on both TCs (TCRs) and BCs (BCRs) is known to continuously evolve with age (Yuseff et al., 2013), the phenomenon of aging-associated TCR and BCR repertoire constriction has not yet been studied at the single-cell level."}