PMC:7417788 / 301-641 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T13","span":{"begin":11,"end":16},"obj":"SO:0002031"},{"id":"T14","span":{"begin":63,"end":69},"obj":"UBERON:0002405;CL:0000738"},{"id":"T15","span":{"begin":70,"end":74},"obj":"CL:0000738"},{"id":"T16","span":{"begin":95,"end":100},"obj":"UBERON:0000178"},{"id":"T17","span":{"begin":157,"end":165},"obj":"SP_7"},{"id":"T18","span":{"begin":185,"end":191},"obj":"UBERON:0002405;CL:0000738"},{"id":"T19","span":{"begin":192,"end":196},"obj":"CL:0000738"},{"id":"T20","span":{"begin":258,"end":264},"obj":"CL:0000084"},{"id":"T21","span":{"begin":293,"end":299},"obj":"GO:0007613"},{"id":"T22","span":{"begin":309,"end":317},"obj":"CHEBI:35224;CHEBI:35224"},{"id":"T73107","span":{"begin":11,"end":16},"obj":"SO:0002031"},{"id":"T65469","span":{"begin":63,"end":69},"obj":"UBERON:0002405;CL:0000738"},{"id":"T31260","span":{"begin":70,"end":74},"obj":"CL:0000738"},{"id":"T36911","span":{"begin":95,"end":100},"obj":"UBERON:0000178"},{"id":"T38094","span":{"begin":157,"end":165},"obj":"SP_7"},{"id":"T8518","span":{"begin":185,"end":191},"obj":"UBERON:0002405;CL:0000738"},{"id":"T10007","span":{"begin":192,"end":196},"obj":"CL:0000738"},{"id":"T60022","span":{"begin":258,"end":264},"obj":"CL:0000084"},{"id":"T9673","span":{"begin":293,"end":299},"obj":"GO:0007613"},{"id":"T13245","span":{"begin":309,"end":317},"obj":"CHEBI:35224;CHEBI:35224"}],"text":"e combined scRNA-seq, mass cytometry and scATAC-seq to compare immune cell types in peripheral blood collected from young and old subjects and patients with COVID-19. We found that the immune cell landscape was reprogrammed with age and was characterized by T cell polarization from naive and memory cells to effector, cytotoxic, exhausted "}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T4","span":{"begin":70,"end":74},"obj":"Body_part"},{"id":"T5","span":{"begin":95,"end":100},"obj":"Body_part"},{"id":"T6","span":{"begin":192,"end":196},"obj":"Body_part"},{"id":"T7","span":{"begin":260,"end":264},"obj":"Body_part"},{"id":"T8","span":{"begin":300,"end":305},"obj":"Body_part"}],"attributes":[{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma9670"},{"id":"A6","pred":"fma_id","subj":"T6","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A7","pred":"fma_id","subj":"T7","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A8","pred":"fma_id","subj":"T8","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"e combined scRNA-seq, mass cytometry and scATAC-seq to compare immune cell types in peripheral blood collected from young and old subjects and patients with COVID-19. We found that the immune cell landscape was reprogrammed with age and was characterized by T cell polarization from naive and memory cells to effector, cytotoxic, exhausted "}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T1","span":{"begin":95,"end":100},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"}],"text":"e combined scRNA-seq, mass cytometry and scATAC-seq to compare immune cell types in peripheral blood collected from young and old subjects and patients with COVID-19. We found that the immune cell landscape was reprogrammed with age and was characterized by T cell polarization from naive and memory cells to effector, cytotoxic, exhausted "}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T3","span":{"begin":157,"end":165},"obj":"Disease"}],"attributes":[{"id":"A3","pred":"mondo_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"e combined scRNA-seq, mass cytometry and scATAC-seq to compare immune cell types in peripheral blood collected from young and old subjects and patients with COVID-19. We found that the immune cell landscape was reprogrammed with age and was characterized by T cell polarization from naive and memory cells to effector, cytotoxic, exhausted "}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T8","span":{"begin":70,"end":80},"obj":"http://purl.obolibrary.org/obo/CL_0000000"},{"id":"T9","span":{"begin":95,"end":100},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T10","span":{"begin":95,"end":100},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T11","span":{"begin":192,"end":196},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T12","span":{"begin":258,"end":264},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T13","span":{"begin":300,"end":305},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"e combined scRNA-seq, mass cytometry and scATAC-seq to compare immune cell types in peripheral blood collected from young and old subjects and patients with COVID-19. We found that the immune cell landscape was reprogrammed with age and was characterized by T cell polarization from naive and memory cells to effector, cytotoxic, exhausted "}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T1","span":{"begin":309,"end":317},"obj":"Chemical"}],"attributes":[{"id":"A1","pred":"chebi_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_35224"}],"text":"e combined scRNA-seq, mass cytometry and scATAC-seq to compare immune cell types in peripheral blood collected from young and old subjects and patients with COVID-19. We found that the immune cell landscape was reprogrammed with age and was characterized by T cell polarization from naive and memory cells to effector, cytotoxic, exhausted "}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T2","span":{"begin":258,"end":277},"obj":"http://purl.obolibrary.org/obo/GO_0001768"},{"id":"T3","span":{"begin":260,"end":277},"obj":"http://purl.obolibrary.org/obo/GO_0030010"},{"id":"T4","span":{"begin":293,"end":299},"obj":"http://purl.obolibrary.org/obo/GO_0007613"}],"text":"e combined scRNA-seq, mass cytometry and scATAC-seq to compare immune cell types in peripheral blood collected from young and old subjects and patients with COVID-19. We found that the immune cell landscape was reprogrammed with age and was characterized by T cell polarization from naive and memory cells to effector, cytotoxic, exhausted "}

{"project":"LitCovid-PubTator","denotations":[{"id":"14","span":{"begin":143,"end":151},"obj":"Species"},{"id":"18","span":{"begin":157,"end":165},"obj":"Disease"}],"attributes":[{"id":"A14","pred":"tao:has_database_id","subj":"14","obj":"Tax:9606"},{"id":"A18","pred":"tao:has_database_id","subj":"18","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"e combined scRNA-seq, mass cytometry and scATAC-seq to compare immune cell types in peripheral blood collected from young and old subjects and patients with COVID-19. We found that the immune cell landscape was reprogrammed with age and was characterized by T cell polarization from naive and memory cells to effector, cytotoxic, exhausted "}