PMC:7417788 / 13570-13910 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T321","span":{"begin":49,"end":55},"obj":"CL:0000236"},{"id":"T322","span":{"begin":65,"end":69},"obj":"PR:000001866"},{"id":"T323","span":{"begin":83,"end":90},"obj":"CL:0000788"},{"id":"T324","span":{"begin":104,"end":108},"obj":"PR:000001963"},{"id":"T325","span":{"begin":117,"end":123},"obj":"GO:0007613"},{"id":"T326","span":{"begin":133,"end":139},"obj":"GO:0007613"},{"id":"T327","span":{"begin":146,"end":158},"obj":"CL:0000786"},{"id":"T328","span":{"begin":172,"end":180},"obj":"GO:0042571"},{"id":"T329","span":{"begin":181,"end":190},"obj":"GO:0048305"},{"id":"T330","span":{"begin":205,"end":215},"obj":"GO:0010467"},{"id":"T331","span":{"begin":230,"end":244},"obj":"GO:0019814"},{"id":"T332","span":{"begin":245,"end":250},"obj":"SO:0002122"},{"id":"T333","span":{"begin":251,"end":255},"obj":"PR:000012212"},{"id":"T334","span":{"begin":273,"end":278},"obj":"PR:000001013"},{"id":"T335","span":{"begin":280,"end":287},"obj":"CL:0000236"},{"id":"T336","span":{"begin":314,"end":321},"obj":"CL:0000236"}],"text":"In addition, we identified four major peripheral B cell subsets: IL4R+ IGHD+ naive B cells (Naive BCs); CD27+ IGHG1+ memory B cells (Memory BCs); plasma cells or so-called antibody-secreting cells (ASCs), expressing high level of immunoglobulin genes MZB1; and a subset of ITGAX+ B cells defined as age-associated B cells (ABCs) (Fig. S3L)."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T142","span":{"begin":51,"end":55},"obj":"Body_part"},{"id":"T143","span":{"begin":85,"end":90},"obj":"Body_part"},{"id":"T144","span":{"begin":126,"end":131},"obj":"Body_part"},{"id":"T145","span":{"begin":146,"end":158},"obj":"Body_part"},{"id":"T146","span":{"begin":146,"end":152},"obj":"Body_part"},{"id":"T147","span":{"begin":153,"end":158},"obj":"Body_part"},{"id":"T148","span":{"begin":172,"end":180},"obj":"Body_part"},{"id":"T149","span":{"begin":191,"end":196},"obj":"Body_part"},{"id":"T150","span":{"begin":230,"end":244},"obj":"Body_part"},{"id":"T151","span":{"begin":282,"end":287},"obj":"Body_part"},{"id":"T152","span":{"begin":316,"end":321},"obj":"Body_part"}],"attributes":[{"id":"A142","pred":"fma_id","subj":"T142","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A143","pred":"fma_id","subj":"T143","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A144","pred":"fma_id","subj":"T144","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A145","pred":"fma_id","subj":"T145","obj":"http://purl.org/sig/ont/fma/fma70574"},{"id":"A146","pred":"fma_id","subj":"T146","obj":"http://purl.org/sig/ont/fma/fma62970"},{"id":"A147","pred":"fma_id","subj":"T147","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A148","pred":"fma_id","subj":"T148","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A149","pred":"fma_id","subj":"T149","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A150","pred":"fma_id","subj":"T150","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A151","pred":"fma_id","subj":"T151","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A152","pred":"fma_id","subj":"T152","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"In addition, we identified four major peripheral B cell subsets: IL4R+ IGHD+ naive B cells (Naive BCs); CD27+ IGHG1+ memory B cells (Memory BCs); plasma cells or so-called antibody-secreting cells (ASCs), expressing high level of immunoglobulin genes MZB1; and a subset of ITGAX+ B cells defined as age-associated B cells (ABCs) (Fig. S3L)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T34","span":{"begin":71,"end":75},"obj":"Disease"}],"attributes":[{"id":"A34","pred":"mondo_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/MONDO_0000050"}],"text":"In addition, we identified four major peripheral B cell subsets: IL4R+ IGHD+ naive B cells (Naive BCs); CD27+ IGHG1+ memory B cells (Memory BCs); plasma cells or so-called antibody-secreting cells (ASCs), expressing high level of immunoglobulin genes MZB1; and a subset of ITGAX+ B cells defined as age-associated B cells (ABCs) (Fig. S3L)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T263","span":{"begin":49,"end":55},"obj":"http://purl.obolibrary.org/obo/CL_0000236"},{"id":"T264","span":{"begin":83,"end":90},"obj":"http://purl.obolibrary.org/obo/CL_0000236"},{"id":"T265","span":{"begin":98,"end":101},"obj":"http://purl.obolibrary.org/obo/CL_0000236"},{"id":"T266","span":{"begin":104,"end":108},"obj":"http://purl.obolibrary.org/obo/PR_000001963"},{"id":"T267","span":{"begin":124,"end":131},"obj":"http://purl.obolibrary.org/obo/CL_0000236"},{"id":"T268","span":{"begin":140,"end":143},"obj":"http://purl.obolibrary.org/obo/CL_0000236"},{"id":"T269","span":{"begin":146,"end":158},"obj":"http://purl.obolibrary.org/obo/CL_0000786"},{"id":"T270","span":{"begin":191,"end":196},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T271","span":{"begin":245,"end":250},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T272","span":{"begin":261,"end":262},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T273","span":{"begin":273,"end":278},"obj":"http://purl.obolibrary.org/obo/PR_000001013"},{"id":"T274","span":{"begin":280,"end":287},"obj":"http://purl.obolibrary.org/obo/CL_0000236"},{"id":"T275","span":{"begin":314,"end":321},"obj":"http://purl.obolibrary.org/obo/CL_0000236"}],"text":"In addition, we identified four major peripheral B cell subsets: IL4R+ IGHD+ naive B cells (Naive BCs); CD27+ IGHG1+ memory B cells (Memory BCs); plasma cells or so-called antibody-secreting cells (ASCs), expressing high level of immunoglobulin genes MZB1; and a subset of ITGAX+ B cells defined as age-associated B cells (ABCs) (Fig. S3L)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T45","span":{"begin":65,"end":69},"obj":"http://purl.obolibrary.org/obo/GO_0004913"},{"id":"T46","span":{"begin":117,"end":123},"obj":"http://purl.obolibrary.org/obo/GO_0007613"},{"id":"T47","span":{"begin":133,"end":139},"obj":"http://purl.obolibrary.org/obo/GO_0007613"}],"text":"In addition, we identified four major peripheral B cell subsets: IL4R+ IGHD+ naive B cells (Naive BCs); CD27+ IGHG1+ memory B cells (Memory BCs); plasma cells or so-called antibody-secreting cells (ASCs), expressing high level of immunoglobulin genes MZB1; and a subset of ITGAX+ B cells defined as age-associated B cells (ABCs) (Fig. S3L)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T62","span":{"begin":0,"end":340},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In addition, we identified four major peripheral B cell subsets: IL4R+ IGHD+ naive B cells (Naive BCs); CD27+ IGHG1+ memory B cells (Memory BCs); plasma cells or so-called antibody-secreting cells (ASCs), expressing high level of immunoglobulin genes MZB1; and a subset of ITGAX+ B cells defined as age-associated B cells (ABCs) (Fig. S3L)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"283","span":{"begin":65,"end":69},"obj":"Gene"},{"id":"284","span":{"begin":71,"end":75},"obj":"Gene"},{"id":"285","span":{"begin":104,"end":108},"obj":"Gene"},{"id":"286","span":{"begin":110,"end":115},"obj":"Gene"},{"id":"287","span":{"begin":251,"end":255},"obj":"Gene"},{"id":"288","span":{"begin":273,"end":278},"obj":"Gene"}],"attributes":[{"id":"A283","pred":"tao:has_database_id","subj":"283","obj":"Gene:3566"},{"id":"A284","pred":"tao:has_database_id","subj":"284","obj":"Gene:3495"},{"id":"A285","pred":"tao:has_database_id","subj":"285","obj":"Gene:939"},{"id":"A286","pred":"tao:has_database_id","subj":"286","obj":"Gene:3500"},{"id":"A287","pred":"tao:has_database_id","subj":"287","obj":"Gene:51237"},{"id":"A288","pred":"tao:has_database_id","subj":"288","obj":"Gene:3687"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In addition, we identified four major peripheral B cell subsets: IL4R+ IGHD+ naive B cells (Naive BCs); CD27+ IGHG1+ memory B cells (Memory BCs); plasma cells or so-called antibody-secreting cells (ASCs), expressing high level of immunoglobulin genes MZB1; and a subset of ITGAX+ B cells defined as age-associated B cells (ABCs) (Fig. S3L)."}