PMC:7417788 / 11835-15256
Annnotations
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T258 | 14-20 | UBERON:0002405;CL:0000738 | denotes | immune |
| T259 | 21-25 | CL:0000738 | denotes | cell |
| T260 | 42-50 | GO:0007569 | denotes | cellular |
| T261 | 51-56 | GO:0007568 | denotes | aging |
| T262 | 227-232 | SO:0000704 | denotes | genes |
| T263 | 357-360 | PR:000001004 | denotes | CD4 |
| T264 | 362-365 | CL:0002488 | denotes | TCs |
| T265 | 408-411 | CL:0002488 | denotes | TCs |
| T266 | 624-629 | GO:0007568 | denotes | Aging |
| T267 | 670-673 | CL:0002488 | denotes | TCs |
| T268 | 724-730 | CL:0000084 | denotes | T cell |
| T269 | 750-753 | PR:000001004 | denotes | CD4 |
| T270 | 762-765 | PR:000001004 | denotes | CD4 |
| T271 | 772-775 | PR:000001004 | denotes | CD4 |
| T272 | 799-806 | CL:0000084 | denotes | T cells |
| T273 | 808-815 | GO:0007067 | denotes | mitotic |
| T274 | 847-857 | GO:0010467 | denotes | expression |
| T275 | 903-906 | PR:000001004 | denotes | CD4 |
| T276 | 908-915 | CL:0000084 | denotes | T cells |
| T277 | 960-967 | PR:000001343 | denotes | CD69low |
| T278 | 974-977 | PR:000001004 | denotes | CD4 |
| T279 | 979-986 | CL:0000084 | denotes | T cells |
| T280 | 988-991 | PR:000001004 | denotes | CD4 |
| T281 | 1008-1016 | PR:000001343 | denotes | CD69high |
| T282 | 1017-1021 | PR:000001202 | denotes | CCR6 |
| T283 | 1031-1037 | GO:0007613 | denotes | memory |
| T284 | 1043-1050 | CL:0000084 | denotes | T cells |
| T285 | 1052-1055 | PR:000001004 | denotes | CD4 |
| T286 | 1062-1066 | PR:000001202 | denotes | CCR6 |
| T287 | 1068-1076 | CHEBI:35224;CHEBI:35224 | denotes | effector |
| T288 | 1077-1083 | GO:0007613 | denotes | memory |
| T289 | 1084-1087 | PR:000001004 | denotes | CD4 |
| T290 | 1089-1096 | CL:0000084 | denotes | T cells |
| T291 | 1098-1101 | PR:000001004 | denotes | CD4 |
| T292 | 1108-1113 | PR:000001350 | denotes | FOXP3 |
| T293 | 1115-1125 | GO:0065007;CL:0000815 | denotes | regulatory |
| T294 | 1126-1133 | CL:0000815 | denotes | T cells |
| T295 | 1135-1138 | PR:000001004 | denotes | CD4 |
| T296 | 1149-1154 | PR:000001919 | denotes | PDCD1 |
| T297 | 1166-1169 | PR:000001004 | denotes | CD4 |
| T298 | 1171-1178 | CL:0000084 | denotes | T cells |
| T299 | 1210-1217 | CL:0000084 | denotes | T cells |
| T300 | 1253-1257 | PR:000001203 | denotes | CCR7 |
| T301 | 1270-1277 | CL:0000084 | denotes | T cells |
| T302 | 1291-1295 | PR:000003472 | denotes | GZMK |
| T303 | 1297-1305 | CHEBI:35224;CHEBI:35224 | denotes | effector |
| T304 | 1306-1312 | GO:0007613 | denotes | memory |
| T305 | 1318-1319 | CL:0000084 | denotes | T |
| T306 | 1382-1387 | PR:000001919 | denotes | PDCD1 |
| T307 | 1404-1411 | CL:0000084 | denotes | T cells |
| T308 | 1446-1453 | CL:0000623 | denotes | NK cell |
| T309 | 1508-1514 | UBERON:0002405 | denotes | immune |
| T310 | 1539-1543 | PR:000001483 | denotes | CD16 |
| T311 | 1545-1551 | PR:000001484 | denotes | FCGR3A |
| T312 | 1556-1560 | PR:000001024 | denotes | CD56 |
| T313 | 1562-1567 | PR:000001024 | denotes | NCAM1 |
| T314 | 1590-1593 | PR:P22807 | denotes | NK1 |
| T315 | 1600-1608 | PR:000001483 | denotes | CD16high |
| T316 | 1609-1616 | PR:000001024 | denotes | CD56dim |
| T317 | 1662-1665 | PR:P22808 | denotes | NK2 |
| T318 | 1675-1683 | PR:000001483 | denotes | CD16high |
| T319 | 1684-1691 | PR:000001024 | denotes | CD56dim |
| T320 | 1718-1721 | PR:P22809 | denotes | NK3 |
| T321 | 1784-1790 | CL:0000236 | denotes | B cell |
| T322 | 1800-1804 | PR:000001866 | denotes | IL4R |
| T323 | 1818-1825 | CL:0000788 | denotes | B cells |
| T324 | 1839-1843 | PR:000001963 | denotes | CD27 |
| T325 | 1852-1858 | GO:0007613 | denotes | memory |
| T326 | 1868-1874 | GO:0007613 | denotes | Memory |
| T327 | 1881-1893 | CL:0000786 | denotes | plasma cells |
| T328 | 1907-1915 | GO:0042571 | denotes | antibody |
| T329 | 1916-1925 | GO:0048305 | denotes | secreting |
| T330 | 1940-1950 | GO:0010467 | denotes | expressing |
| T331 | 1965-1979 | GO:0019814 | denotes | immunoglobulin |
| T332 | 1980-1985 | SO:0002122 | denotes | genes |
| T333 | 1986-1990 | PR:000012212 | denotes | MZB1 |
| T334 | 2008-2013 | PR:000001013 | denotes | ITGAX |
| T335 | 2015-2022 | CL:0000236 | denotes | B cells |
| T336 | 2049-2056 | CL:0000236 | denotes | B cells |
| T337 | 2079-2084 | SP_6;NCBITaxon:9606 | denotes | human |
| T338 | 2085-2095 | CL:0000080 | denotes | peripheral |
| T339 | 2096-2101 | CL:0000080;UBERON:0000178 | denotes | blood |
| T340 | 2102-2115 | CL:0000763 | denotes | myeloid cells |
| T341 | 2127-2130 | CL:0000576 | denotes | MCs |
| T342 | 2158-2165 | CHEBI:59132;CHEBI:59132;GO:0016064 | denotes | antigen |
| T343 | 2264-2272 | PR:000001889 | denotes | CD14high |
| T344 | 2273-2277 | PR:000001483 | denotes | CD16 |
| T345 | 2289-2298 | CL:0000860 | denotes | monocytes |
| T346 | 2300-2304 | PR:000001889 | denotes | CD14 |
| T347 | 2311-2315 | PR:000001889 | denotes | CD14 |
| T348 | 2319-2327 | PR:000001483 | denotes | CD16high |
| T349 | 2341-2350 | CL:0000576 | denotes | monocytes |
| T350 | 2352-2356 | PR:000001483 | denotes | CD16 |
| T351 | 2363-2367 | PR:000001889 | denotes | CD14 |
| T352 | 2369-2373 | PR:000001483 | denotes | CD16 |
| T353 | 2377-2399 | CL:0002393 | denotes | intermediate monocytes |
| T354 | 2460-2464 | PR:000002027 | denotes | CD1c |
| T355 | 2496-2501 | PR:000001865 | denotes | CD123 |
| T356 | 2503-2508 | PR:000001865 | denotes | IL3RA |
| T357 | 2511-2517 | PR:000001292 | denotes | CLEC4C |
| T358 | 2537-2541 | CL:0000784 | denotes | pDCs |
| T359 | 2559-2568 | GO:0030425;CL:0000451 | denotes | dendritic |
| T360 | 2569-2573 | CL:0000451 | denotes | cell |
| T361 | 2595-2605 | GO:0010467 | denotes | expressing |
| T362 | 2614-2619 | PR:000001865 | denotes | CD123 |
| T363 | 2708-2714 | UBERON:0002405;CL:0000738 | denotes | immune |
| T364 | 2715-2719 | CL:0000738 | denotes | cell |
| T365 | 2805-2810 | GO:0007568 | denotes | aging |
| T366 | 3042-3045 | PR:000001004 | denotes | CD4 |
| T367 | 3053-3056 | PR:000001004 | denotes | CD4 |
| T368 | 3062-3065 | PR:000001004 | denotes | CD4 |
| T369 | 3071-3074 | PR:000001004 | denotes | CD4 |
| T370 | 3110-3113 | PR:000001004 | denotes | CD4 |
| T371 | 3121-3124 | PR:000001004 | denotes | CD4 |
| T372 | 3155-3165 | PR:000001024 | denotes | CD56bright |
| T373 | 3166-3169 | PR:P22807 | denotes | NK1 |
| T374 | 3171-3175 | PR:000001483 | denotes | CD16 |
| T375 | 3182-3185 | PR:P22808 | denotes | NK2 |
| T376 | 3190-3194 | PR:000001483 | denotes | CD16 |
| T377 | 3201-3204 | PR:P22809 | denotes | NK3 |
| T378 | 3238-3244 | GO:0007613 | denotes | Memory |
| T379 | 3288-3296 | PR:000001889 | denotes | CD14high |
| T380 | 3302-3310 | PR:000001483 | denotes | CD16high |
| T381 | 3319-3335 | CL:0002486 | denotes | intermediate MCs |
| T382 | 3362-3366 | CL:0000784;CHEBI:76777;CHEBI:76777 | denotes | pDCs |
| T383 | 3371-3375 | CL:0000990 | denotes | cDCs |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T119 | 21-25 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T120 | 84-88 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T121 | 156-161 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T122 | 450-453 | Body_part | denotes | NKs | http://purl.org/sig/ont/fma/fma63147 |
| T123 | 678-681 | Body_part | denotes | NKs | http://purl.org/sig/ont/fma/fma63147 |
| T124 | 726-730 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T125 | 801-806 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T126 | 818-823 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T127 | 910-915 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T128 | 981-986 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T129 | 1045-1050 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T130 | 1091-1096 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T131 | 1115-1133 | Body_part | denotes | regulatory T cells | http://purl.org/sig/ont/fma/fma84070 |
| T132 | 1128-1133 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T133 | 1173-1178 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T134 | 1212-1217 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T135 | 1272-1277 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T136 | 1320-1325 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T137 | 1406-1411 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T138 | 1446-1453 | Body_part | denotes | NK cell | http://purl.org/sig/ont/fma/fma63147 |
| T139 | 1449-1453 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T140 | 1484-1487 | Body_part | denotes | NKs | http://purl.org/sig/ont/fma/fma63147 |
| T141 | 1649-1660 | Body_part | denotes | compartment | http://purl.org/sig/ont/fma/fma76577 |
| T142 | 1786-1790 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T143 | 1820-1825 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T144 | 1861-1866 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T145 | 1881-1893 | Body_part | denotes | plasma cells | http://purl.org/sig/ont/fma/fma70574 |
| T146 | 1881-1887 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T147 | 1888-1893 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T148 | 1907-1915 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
| T149 | 1926-1931 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T150 | 1965-1979 | Body_part | denotes | immunoglobulin | http://purl.org/sig/ont/fma/fma62871 |
| T151 | 2017-2022 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T152 | 2051-2056 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T153 | 2096-2101 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
| T154 | 2102-2115 | Body_part | denotes | myeloid cells | http://purl.org/sig/ont/fma/fma70339 |
| T155 | 2110-2115 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T156 | 2289-2298 | Body_part | denotes | monocytes | http://purl.org/sig/ont/fma/fma62864 |
| T157 | 2341-2350 | Body_part | denotes | monocytes | http://purl.org/sig/ont/fma/fma62864 |
| T158 | 2390-2399 | Body_part | denotes | monocytes | http://purl.org/sig/ont/fma/fma62864 |
| T159 | 2559-2573 | Body_part | denotes | dendritic cell | http://purl.org/sig/ont/fma/fma273565 |
| T160 | 2569-2573 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T161 | 2715-2719 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T162 | 2836-2840 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T163 | 2868-2872 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T164 | 2889-2896 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T165 | 2919-2932 | Body_part | denotes | cell clusters | http://purl.org/sig/ont/fma/fma62807 |
| T166 | 2919-2923 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T167 | 3150-3153 | Body_part | denotes | NKs | http://purl.org/sig/ont/fma/fma63147 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T11 | 2096-2101 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T12 | 2919-2932 | Body_part | denotes | cell clusters | http://purl.obolibrary.org/obo/UBERON_0034922 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T34 | 1806-1810 | Disease | denotes | IGHD | http://purl.obolibrary.org/obo/MONDO_0000050 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T197 | 21-25 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T198 | 84-88 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T199 | 156-161 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T200 | 227-232 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | genes |
| T201 | 311-314 | http://purl.obolibrary.org/obo/CLO_0052882 | denotes | CD3 |
| T202 | 311-314 | http://purl.obolibrary.org/obo/CLO_0053434 | denotes | CD3 |
| T203 | 316-319 | http://purl.obolibrary.org/obo/CLO_0050938 | denotes | TCs |
| T204 | 316-319 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | TCs |
| T205 | 357-360 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
| T206 | 362-365 | http://purl.obolibrary.org/obo/CLO_0050938 | denotes | TCs |
| T207 | 362-365 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | TCs |
| T208 | 403-406 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
| T209 | 408-411 | http://purl.obolibrary.org/obo/CLO_0050938 | denotes | TCs |
| T210 | 408-411 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | TCs |
| T211 | 450-453 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NKs |
| T212 | 491-494 | http://purl.obolibrary.org/obo/CL_0000236 | denotes | BCs |
| T213 | 533-536 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | MCs |
| T214 | 577-580 | http://purl.obolibrary.org/obo/CL_0000451 | denotes | DCs |
| T215 | 670-673 | http://purl.obolibrary.org/obo/CLO_0050938 | denotes | TCs |
| T216 | 670-673 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | TCs |
| T217 | 678-681 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NKs |
| T218 | 724-730 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cell |
| T219 | 750-753 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
| T220 | 756-759 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
| T221 | 762-765 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
| T222 | 766-769 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
| T223 | 772-775 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
| T224 | 776-779 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
| T225 | 799-806 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
| T226 | 816-823 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
| T227 | 903-906 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
| T228 | 908-915 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
| T229 | 968-986 | http://purl.obolibrary.org/obo/CL_0000895 | denotes | naive CD4+ T cells |
| T230 | 988-991 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
| T231 | 1038-1041 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
| T232 | 1043-1050 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
| T233 | 1052-1055 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
| T234 | 1084-1087 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
| T235 | 1089-1096 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
| T236 | 1098-1101 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
| T237 | 1108-1113 | http://purl.obolibrary.org/obo/PR_000001350 | denotes | FOXP3 |
| T238 | 1115-1133 | http://purl.obolibrary.org/obo/CL_0000815 | denotes | regulatory T cells |
| T239 | 1135-1138 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
| T240 | 1139-1143 | http://purl.obolibrary.org/obo/CL_0000792 | denotes | Treg |
| T241 | 1166-1169 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
| T242 | 1171-1178 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
| T243 | 1180-1183 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
| T244 | 1205-1208 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
| T245 | 1210-1217 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
| T246 | 1253-1257 | http://purl.obolibrary.org/obo/PR_000001203 | denotes | CCR7 |
| T247 | 1265-1268 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
| T248 | 1270-1277 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
| T249 | 1279-1282 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
| T250 | 1313-1316 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
| T251 | 1318-1325 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
| T252 | 1327-1330 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
| T253 | 1359-1362 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
| T254 | 1364-1367 | http://purl.obolibrary.org/obo/CLO_0050938 | denotes | TCs |
| T255 | 1364-1367 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | TCs |
| T256 | 1369-1372 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
| T257 | 1399-1402 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
| T258 | 1404-1411 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
| T259 | 1413-1416 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
| T260 | 1446-1453 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cell |
| T261 | 1484-1487 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NKs |
| T262 | 1562-1567 | http://purl.obolibrary.org/obo/PR_000001024 | denotes | NCAM1 |
| T263 | 1784-1790 | http://purl.obolibrary.org/obo/CL_0000236 | denotes | B cell |
| T264 | 1818-1825 | http://purl.obolibrary.org/obo/CL_0000236 | denotes | B cells |
| T265 | 1833-1836 | http://purl.obolibrary.org/obo/CL_0000236 | denotes | BCs |
| T266 | 1839-1843 | http://purl.obolibrary.org/obo/PR_000001963 | denotes | CD27 |
| T267 | 1859-1866 | http://purl.obolibrary.org/obo/CL_0000236 | denotes | B cells |
| T268 | 1875-1878 | http://purl.obolibrary.org/obo/CL_0000236 | denotes | BCs |
| T269 | 1881-1893 | http://purl.obolibrary.org/obo/CL_0000786 | denotes | plasma cells |
| T270 | 1926-1931 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T271 | 1980-1985 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | genes |
| T272 | 1996-1997 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T273 | 2008-2013 | http://purl.obolibrary.org/obo/PR_000001013 | denotes | ITGAX |
| T274 | 2015-2022 | http://purl.obolibrary.org/obo/CL_0000236 | denotes | B cells |
| T275 | 2049-2056 | http://purl.obolibrary.org/obo/CL_0000236 | denotes | B cells |
| T276 | 2079-2084 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T277 | 2096-2101 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T278 | 2096-2101 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T279 | 2110-2115 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T280 | 2127-2130 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | MCs |
| T281 | 2135-2138 | http://purl.obolibrary.org/obo/CL_0000451 | denotes | DCs |
| T282 | 2196-2206 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
| T283 | 2289-2298 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | monocytes |
| T284 | 2305-2308 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | MCs |
| T285 | 2341-2350 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | monocytes |
| T286 | 2357-2360 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | MCs |
| T287 | 2390-2399 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | monocytes |
| T288 | 2410-2413 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | MCs |
| T289 | 2448-2451 | http://purl.obolibrary.org/obo/CL_0000990 | denotes | DC1 |
| T290 | 2484-2487 | http://purl.obolibrary.org/obo/CL_0000784 | denotes | DC2 |
| T291 | 2532-2535 | http://purl.obolibrary.org/obo/CL_0000451 | denotes | DCs |
| T292 | 2559-2573 | http://purl.obolibrary.org/obo/CL_0000451 | denotes | dendritic cell |
| T293 | 2590-2593 | http://purl.obolibrary.org/obo/CL_0000451 | denotes | DCs |
| T294 | 2715-2719 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T295 | 2836-2840 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T296 | 2868-2872 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T297 | 2919-2932 | http://purl.obolibrary.org/obo/UBERON_0034922 | denotes | cell clusters |
| T298 | 3037-3040 | http://purl.obolibrary.org/obo/CLO_0050938 | denotes | TCs |
| T299 | 3037-3040 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | TCs |
| T300 | 3042-3045 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
| T301 | 3053-3056 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
| T302 | 3062-3065 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
| T303 | 3071-3074 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
| T304 | 3075-3079 | http://purl.obolibrary.org/obo/CL_0000792 | denotes | Treg |
| T305 | 3081-3084 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
| T306 | 3092-3095 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
| T307 | 3101-3104 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
| T308 | 3110-3113 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
| T309 | 3115-3118 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
| T310 | 3121-3124 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
| T311 | 3126-3129 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
| T312 | 3150-3153 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NKs |
| T313 | 3223-3226 | http://purl.obolibrary.org/obo/CL_0000236 | denotes | BCs |
| T314 | 3283-3286 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | MCs |
| T315 | 3297-3300 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | MCs |
| T316 | 3311-3314 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | MCs |
| T317 | 3332-3335 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | MCs |
| T318 | 3357-3360 | http://purl.obolibrary.org/obo/CL_0000451 | denotes | DCs |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T40 | 1068-1076 | Chemical | denotes | effector | http://purl.obolibrary.org/obo/CHEBI_35224 |
| T41 | 1297-1305 | Chemical | denotes | effector | http://purl.obolibrary.org/obo/CHEBI_35224 |
| T42 | 2158-2165 | Chemical | denotes | antigen | http://purl.obolibrary.org/obo/CHEBI_59132 |
| T43 | 2889-2896 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T40 | 51-56 | http://purl.obolibrary.org/obo/GO_0007568 | denotes | aging |
| T41 | 624-629 | http://purl.obolibrary.org/obo/GO_0007568 | denotes | Aging |
| T42 | 1031-1037 | http://purl.obolibrary.org/obo/GO_0007613 | denotes | memory |
| T43 | 1077-1083 | http://purl.obolibrary.org/obo/GO_0007613 | denotes | memory |
| T44 | 1306-1312 | http://purl.obolibrary.org/obo/GO_0007613 | denotes | memory |
| T45 | 1800-1804 | http://purl.obolibrary.org/obo/GO_0004913 | denotes | IL4R |
| T46 | 1852-1858 | http://purl.obolibrary.org/obo/GO_0007613 | denotes | memory |
| T47 | 1868-1874 | http://purl.obolibrary.org/obo/GO_0007613 | denotes | Memory |
| T48 | 2158-2178 | http://purl.obolibrary.org/obo/GO_0019882 | denotes | antigen presentation |
| T49 | 2228-2245 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcriptionally |
| T50 | 2805-2810 | http://purl.obolibrary.org/obo/GO_0007568 | denotes | aging |
| T51 | 3238-3244 | http://purl.obolibrary.org/obo/GO_0007613 | denotes | Memory |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T54 | 0-66 | Sentence | denotes | Dissection of immune cell subtypes in the cellular aging ecosystem |
| T55 | 67-178 | Sentence | denotes | To classify each cell subpopulation in an unbiased manner, we separately reclustered the cells of each lineage. |
| T56 | 179-623 | Sentence | denotes | By analyzing the most significantly upregulated genes in each cluster in scRNA-seq analysis, we identified five distinct subsets of CD3+ TCs (Fig. S3A), five distinct subsets of CD4+ TCs (Fig. S3B), four distinct subsets of CD8+ TCs (Fig. S3C), three distinct subsets of NKs (Fig. S3D), four distinct subsets of BCs (Fig. S3E), three distinct subsets of MCs (Fig. S3F) and four distinct subsets of DCs (Fig. S3G, see Table S3A for the details). |
| T57 | 624-703 | Sentence | denotes | Aging affects the development and function of TCs and NKs (Pinti et al., 2016). |
| T58 | 704-898 | Sentence | denotes | We identified known T cell subsets, including CD4+, CD8+, CD4+CD8+, CD4−CD8− and proliferative T cells (mitotic T cells, T-mito), based on the expression of canonical lineage markers (Fig. S3H). |
| T59 | 899-1200 | Sentence | denotes | The CD4+ T cells were subdivided into five classes: CCR7high CD69low naive CD4+ T cells (CD4 Naive); CCR7med CD69high CCR6− central memory CD4+ T cells (CD4 Tcm); CCR6+ effector memory CD4+ T cells (CD4 Tem); FOXP3+ regulatory T cells (CD4 Treg) and PDCD1+ exhausted CD4+ T cells (CD4 Tex) (Fig. S3I). |
| T60 | 1201-1433 | Sentence | denotes | The CD8+ T cells were subdivided into four classes: CCR7+ naive CD8+ T cells (CD8 Naive); GZMK+ effector memory CD8+ T cells (CD8 Tem); GZMB+ GNLY+ cytotoxic CD8+ TCs (CD8 CTL) and PDCD1+ exhausted CD8+ T cells (CD8 Tex) (Fig. S3J). |
| T61 | 1434-1734 | Sentence | denotes | Analysis of NK cell-status identified circulating NKs with three separate immune states (Fig. S 3D): the CD16 (FCGR3A)low CD56 (NCAM1)bright NK population (NK1), the CD16high CD56dim CD57 (B3GAT1)− low-cytotoxic NK compartment (NK2) and the CD16high CD56dim CD57+ late NK population (NK3) (Fig. S3K). |
| T62 | 1735-2075 | Sentence | denotes | In addition, we identified four major peripheral B cell subsets: IL4R+ IGHD+ naive B cells (Naive BCs); CD27+ IGHG1+ memory B cells (Memory BCs); plasma cells or so-called antibody-secreting cells (ASCs), expressing high level of immunoglobulin genes MZB1; and a subset of ITGAX+ B cells defined as age-associated B cells (ABCs) (Fig. S3L). |
| T63 | 2076-2680 | Sentence | denotes | In human peripheral blood myeloid cells (including MCs and DCs), known to promote antigen presentation and inflammatory activities, we identified seven transcriptionally distinct subsets: CD14high CD16− classical monocytes (CD14 MCs), CD14+/− CD16high nonclassical monocytes (CD16 MCs), CD14+ CD16+/− intermediate monocytes (Intermed MCs) (Fig. S3M), CLEC9A+ conventional DC1 (cDC1), CD1c+ cDC2 conventional DC2 (cDC2), CD123 (IL3RA)+ CLEC4C+ plasmacytoid DCs (pDCs) (Fig. S3N), and dendritic cell precursors (pre-DCs) expressing AXL and CD123 (Grabiec and Hussell, 2016; Ruffin et al., 2019) (Fig. S3N). |
| T64 | 2681-2782 | Sentence | denotes | Therefore, we targeted the immune cell changes based on more precise classification of each subgroup. |
| T65 | 2783-2903 | Sentence | denotes | To further verify the aging-associated change in the cell ratio, we performed single-cell analysis at the protein level. |
| T66 | 2904-3421 | Sentence | denotes | Similar to the cell clusters and subsets in scRNA-seq results, in CyTOF analysis, we identified 21 sub-clusters with nine subsets of TCs (CD4 Naive, CD4 Tcm, CD4 Tem, CD4 Treg, CD8 Naive, CD8 Tem, CD8 CTL, CD4+ CD8+, CD4− CD8−), three subsets of NKs (CD56bright NK1, CD16+CD57− NK2 and CD16+CD57+ NK3), four subsets of BCs (Naive BC, Memory BC, ASCs, and ABCs), three subsets of MCs (CD14high MCs, CD16high MCs and intermediate MCs), and two subsets of DCs (pDCs and cDCs) (Fig. S4A–K, see Table S3B for the details). |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32780218-29706550-132718693 | 697-701 | 29706550 | denotes | 2016 |
| 32780218-29706550-132718694 | 2642-2646 | 29706550 | denotes | 2016 |
| 32780218-29891535-132718695 | 2663-2667 | 29891535 | denotes | 2019 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 165 | 357-360 | Gene | denotes | CD4 | Gene:920 |
| 166 | 403-406 | Gene | denotes | CD8 | Gene:925 |
| 167 | 241-248 | Species | denotes | cluster | Tax:100569 |
| 208 | 750-753 | Gene | denotes | CD4 | Gene:920 |
| 209 | 756-759 | Gene | denotes | CD8 | Gene:925 |
| 210 | 762-765 | Gene | denotes | CD4 | Gene:920 |
| 211 | 766-769 | Gene | denotes | CD8 | Gene:925 |
| 212 | 772-775 | Gene | denotes | CD4 | Gene:920 |
| 213 | 776-779 | Gene | denotes | CD8 | Gene:925 |
| 214 | 903-906 | Gene | denotes | CD4 | Gene:920 |
| 215 | 951-955 | Gene | denotes | CCR7 | Gene:1236 |
| 216 | 960-964 | Gene | denotes | CD69 | Gene:969 |
| 217 | 974-977 | Gene | denotes | CD4 | Gene:920 |
| 218 | 988-991 | Gene | denotes | CD4 | Gene:920 |
| 219 | 1000-1004 | Gene | denotes | CCR7 | Gene:1236 |
| 220 | 1008-1012 | Gene | denotes | CD69 | Gene:969 |
| 221 | 1017-1021 | Gene | denotes | CCR6 | Gene:1235 |
| 222 | 1038-1041 | Gene | denotes | CD4 | Gene:920 |
| 223 | 1052-1055 | Gene | denotes | CD4 | Gene:920 |
| 224 | 1062-1066 | Gene | denotes | CCR6 | Gene:1235 |
| 225 | 1084-1087 | Gene | denotes | CD4 | Gene:920 |
| 226 | 1098-1101 | Gene | denotes | CD4 | Gene:920 |
| 227 | 1108-1113 | Gene | denotes | FOXP3 | Gene:50943 |
| 228 | 1135-1138 | Gene | denotes | CD4 | Gene:920 |
| 229 | 1149-1154 | Gene | denotes | PDCD1 | Gene:5133 |
| 230 | 1166-1169 | Gene | denotes | CD4 | Gene:920 |
| 231 | 1180-1183 | Gene | denotes | CD4 | Gene:920 |
| 232 | 1205-1208 | Gene | denotes | CD8 | Gene:925 |
| 233 | 1253-1257 | Gene | denotes | CCR7 | Gene:1236 |
| 234 | 1265-1268 | Gene | denotes | CD8 | Gene:925 |
| 235 | 1291-1295 | Gene | denotes | GZMK | Gene:3003 |
| 236 | 1313-1316 | Gene | denotes | CD8 | Gene:925 |
| 237 | 1327-1330 | Gene | denotes | CD8 | Gene:925 |
| 238 | 1337-1341 | Gene | denotes | GZMB | Gene:3002 |
| 239 | 1343-1347 | Gene | denotes | GNLY | Gene:10578 |
| 240 | 1359-1362 | Gene | denotes | CD8 | Gene:925 |
| 241 | 1369-1372 | Gene | denotes | CD8 | Gene:925 |
| 242 | 1382-1387 | Gene | denotes | PDCD1 | Gene:5133 |
| 243 | 1399-1402 | Gene | denotes | CD8 | Gene:925 |
| 244 | 1413-1416 | Gene | denotes | CD8 | Gene:925 |
| 245 | 1331-1334 | Gene | denotes | Tem | Gene:100188881 |
| 246 | 1102-1105 | Gene | denotes | Tem | Gene:100188881 |
| 247 | 1279-1282 | Gene | denotes | CD8 | Gene:925 |
| 269 | 1539-1543 | Gene | denotes | CD16 | Gene:2214 |
| 270 | 1545-1551 | Gene | denotes | FCGR3A | Gene:2214 |
| 271 | 1556-1560 | Gene | denotes | CD56 | Gene:4684 |
| 272 | 1562-1567 | Gene | denotes | NCAM1 | Gene:4684 |
| 273 | 1590-1593 | Gene | denotes | NK1 | Gene:27087 |
| 274 | 1600-1604 | Gene | denotes | CD16 | Gene:2214 |
| 275 | 1609-1613 | Gene | denotes | CD56 | Gene:4684 |
| 276 | 1617-1621 | Gene | denotes | CD57 | Gene:27087 |
| 277 | 1623-1629 | Gene | denotes | B3GAT1 | Gene:27087 |
| 278 | 1662-1665 | Gene | denotes | NK2 | Gene:7080 |
| 279 | 1675-1679 | Gene | denotes | CD16 | Gene:2214 |
| 280 | 1684-1688 | Gene | denotes | CD56 | Gene:4684 |
| 281 | 1692-1696 | Gene | denotes | CD57 | Gene:27087 |
| 282 | 1703-1722 | Gene | denotes | NK population (NK3) | Gene:4824 |
| 283 | 1800-1804 | Gene | denotes | IL4R | Gene:3566 |
| 284 | 1806-1810 | Gene | denotes | IGHD | Gene:3495 |
| 285 | 1839-1843 | Gene | denotes | CD27 | Gene:939 |
| 286 | 1845-1850 | Gene | denotes | IGHG1 | Gene:3500 |
| 287 | 1986-1990 | Gene | denotes | MZB1 | Gene:51237 |
| 288 | 2008-2013 | Gene | denotes | ITGAX | Gene:3687 |
| 289 | 1575-1589 | Gene | denotes | NK population | Gene:4824 |
| 309 | 2264-2268 | Gene | denotes | CD14 | Gene:929 |
| 310 | 2273-2277 | Gene | denotes | CD16 | Gene:2214 |
| 311 | 2300-2304 | Gene | denotes | CD14 | Gene:929 |
| 312 | 2311-2315 | Gene | denotes | CD14 | Gene:929 |
| 313 | 2319-2323 | Gene | denotes | CD16 | Gene:2214 |
| 314 | 2352-2356 | Gene | denotes | CD16 | Gene:2214 |
| 315 | 2363-2367 | Gene | denotes | CD14 | Gene:929 |
| 316 | 2369-2373 | Gene | denotes | CD16 | Gene:2214 |
| 317 | 2427-2433 | Gene | denotes | CLEC9A | Gene:283420 |
| 318 | 2460-2464 | Gene | denotes | CD1c | Gene:911 |
| 319 | 2466-2470 | Gene | denotes | cDC2 | Gene:983 |
| 320 | 2484-2487 | Gene | denotes | DC2 | Gene:58505 |
| 321 | 2489-2493 | Gene | denotes | cDC2 | Gene:983 |
| 322 | 2496-2501 | Gene | denotes | CD123 | Gene:3563 |
| 323 | 2503-2508 | Gene | denotes | IL3RA | Gene:3563 |
| 324 | 2511-2517 | Gene | denotes | CLEC4C | Gene:170482 |
| 325 | 2606-2609 | Gene | denotes | AXL | Gene:558 |
| 326 | 2614-2619 | Gene | denotes | CD123 | Gene:3563 |
| 327 | 2079-2084 | Species | denotes | human | Tax:9606 |
| 351 | 3042-3045 | Gene | denotes | CD4 | Gene:920 |
| 352 | 3053-3056 | Gene | denotes | CD4 | Gene:920 |
| 353 | 3062-3065 | Gene | denotes | CD4 | Gene:920 |
| 354 | 3071-3074 | Gene | denotes | CD4 | Gene:920 |
| 355 | 3081-3084 | Gene | denotes | CD8 | Gene:925 |
| 356 | 3092-3095 | Gene | denotes | CD8 | Gene:925 |
| 357 | 3101-3104 | Gene | denotes | CD8 | Gene:925 |
| 358 | 3110-3113 | Gene | denotes | CD4 | Gene:920 |
| 359 | 3115-3118 | Gene | denotes | CD8 | Gene:925 |
| 360 | 3121-3124 | Gene | denotes | CD4 | Gene:920 |
| 361 | 3126-3129 | Gene | denotes | CD8 | Gene:925 |
| 362 | 3155-3159 | Gene | denotes | CD56 | Gene:4684 |
| 363 | 3166-3169 | Gene | denotes | NK1 | Gene:27087 |
| 364 | 3171-3175 | Gene | denotes | CD16 | Gene:2214 |
| 365 | 3176-3180 | Gene | denotes | CD57 | Gene:27087 |
| 366 | 3182-3185 | Gene | denotes | NK2 | Gene:7080 |
| 367 | 3190-3194 | Gene | denotes | CD16 | Gene:2214 |
| 368 | 3195-3199 | Gene | denotes | CD57 | Gene:27087 |
| 369 | 3201-3204 | Gene | denotes | NK3 | Gene:4824 |
| 370 | 3288-3292 | Gene | denotes | CD14 | Gene:929 |
| 371 | 3302-3306 | Gene | denotes | CD16 | Gene:2214 |
| 372 | 3096-3099 | Gene | denotes | Tem | Gene:100188881 |
| 373 | 3066-3069 | Gene | denotes | Tem | Gene:100188881 |