PMC:7417201 / 2452-3824
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7417201","sourcedb":"PMC","sourceid":"7417201","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7417201","text":"Italy was among the first countries dramatically stricken by COVID-19 outbreak [7]. Therefore, the evaluation of the impact of containment measures against COVID-19 spread on the non-COVID-19 diseases in Italy may measure the magnitude of the effect on larger scale. Piccolo et al. [8] recently investigated the association between the outbreak of COVID-19 and percutaneous coronary intervention (PCI) rates for acute coronary syndrome (ACS) in the Campania region, accounting for about 10% of the entire Italian population. They found evidence that the outbreak of COVID-19 was associated with a decline by 32% in the number of PCI for ACS suggesting two potential explanations. If on one hand chest pain, which is the most frightening sign who lead patients to emergency room, might be underestimated due to the COVID-19 fear, on the other, physical activity that might trigger an ACS has significantly decreased during lockdown. The aim of this study was to assess the impact of the COVID-19 pandemic on stress single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) work-up for ischemic heart disease during the lockdown imposed by the Italian Government [7]. For this purpose, we reviewed the data of stress SPECT-MPI performed between February and May 2020, in comparison with the corresponding months of the years 2017, 2018, and 2019.","tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T4","span":{"begin":690,"end":694},"obj":"Body_part"},{"id":"T5","span":{"begin":695,"end":700},"obj":"Body_part"},{"id":"T6","span":{"begin":1121,"end":1126},"obj":"Body_part"}],"attributes":[{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma9712"},{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma9576"},{"id":"A6","pred":"fma_id","subj":"T6","obj":"http://purl.org/sig/ont/fma/fma7088"},{"subj":"T4","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T5","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T6","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T5","span":{"begin":260,"end":265},"obj":"Body_part"},{"id":"T6","span":{"begin":690,"end":694},"obj":"Body_part"},{"id":"T7","span":{"begin":695,"end":700},"obj":"Body_part"},{"id":"T8","span":{"begin":1121,"end":1126},"obj":"Body_part"}],"attributes":[{"id":"A5","pred":"uberon_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/UBERON_0002542"},{"id":"A6","pred":"uberon_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/UBERON_0002398"},{"id":"A7","pred":"uberon_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/UBERON_0001443"},{"id":"A8","pred":"uberon_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"subj":"T5","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T6","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T7","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T8","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T16","span":{"begin":61,"end":69},"obj":"Disease"},{"id":"T17","span":{"begin":156,"end":164},"obj":"Disease"},{"id":"T18","span":{"begin":183,"end":191},"obj":"Disease"},{"id":"T19","span":{"begin":348,"end":356},"obj":"Disease"},{"id":"T20","span":{"begin":412,"end":435},"obj":"Disease"},{"id":"T21","span":{"begin":566,"end":574},"obj":"Disease"},{"id":"T22","span":{"begin":814,"end":822},"obj":"Disease"},{"id":"T23","span":{"begin":986,"end":994},"obj":"Disease"},{"id":"T24","span":{"begin":1112,"end":1134},"obj":"Disease"},{"id":"T25","span":{"begin":1121,"end":1134},"obj":"Disease"}],"attributes":[{"id":"A16","pred":"mondo_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A17","pred":"mondo_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A18","pred":"mondo_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A19","pred":"mondo_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A20","pred":"mondo_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/MONDO_0005542"},{"id":"A21","pred":"mondo_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A22","pred":"mondo_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A23","pred":"mondo_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A24","pred":"mondo_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/MONDO_0024644"},{"id":"A25","pred":"mondo_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/MONDO_0005267"},{"subj":"T16","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T17","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T18","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T19","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T20","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T21","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T22","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T23","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T24","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T25","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T21","span":{"begin":595,"end":596},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T22","span":{"begin":695,"end":700},"obj":"http://www.ebi.ac.uk/efo/EFO_0000965"},{"id":"T23","span":{"begin":852,"end":860},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T24","span":{"begin":887,"end":890},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T25","span":{"begin":936,"end":939},"obj":"http://purl.obolibrary.org/obo/PR_000001343"},{"id":"T26","span":{"begin":1121,"end":1126},"obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"T27","span":{"begin":1121,"end":1126},"obj":"http://purl.obolibrary.org/obo/UBERON_0007100"},{"id":"T28","span":{"begin":1121,"end":1126},"obj":"http://purl.obolibrary.org/obo/UBERON_0015228"},{"id":"T29","span":{"begin":1121,"end":1126},"obj":"http://www.ebi.ac.uk/efo/EFO_0000815"},{"id":"T30","span":{"begin":1357,"end":1361},"obj":"http://purl.obolibrary.org/obo/CLO_0001185"}],"attributes":[{"subj":"T21","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T22","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T23","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T24","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T25","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T26","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T27","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T28","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T29","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T30","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T4","span":{"begin":1021,"end":1027},"obj":"Chemical"}],"attributes":[{"id":"A4","pred":"chebi_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_30212"},{"subj":"T4","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T20","span":{"begin":0,"end":83},"obj":"Sentence"},{"id":"T21","span":{"begin":84,"end":266},"obj":"Sentence"},{"id":"T22","span":{"begin":267,"end":524},"obj":"Sentence"},{"id":"T23","span":{"begin":525,"end":679},"obj":"Sentence"},{"id":"T24","span":{"begin":680,"end":931},"obj":"Sentence"},{"id":"T25","span":{"begin":932,"end":1193},"obj":"Sentence"},{"id":"T26","span":{"begin":1194,"end":1372},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T20","pred":"source","obj":"LitCovid-sentences"},{"subj":"T21","pred":"source","obj":"LitCovid-sentences"},{"subj":"T22","pred":"source","obj":"LitCovid-sentences"},{"subj":"T23","pred":"source","obj":"LitCovid-sentences"},{"subj":"T24","pred":"source","obj":"LitCovid-sentences"},{"subj":"T25","pred":"source","obj":"LitCovid-sentences"},{"subj":"T26","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T1","span":{"begin":695,"end":705},"obj":"Phenotype"}],"attributes":[{"id":"A1","pred":"hp_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/HP_0100749"},{"subj":"T1","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"35","span":{"begin":751,"end":759},"obj":"Species"},{"id":"36","span":{"begin":61,"end":69},"obj":"Disease"},{"id":"37","span":{"begin":156,"end":164},"obj":"Disease"},{"id":"38","span":{"begin":183,"end":191},"obj":"Disease"},{"id":"39","span":{"begin":348,"end":356},"obj":"Disease"},{"id":"40","span":{"begin":418,"end":435},"obj":"Disease"},{"id":"41","span":{"begin":566,"end":574},"obj":"Disease"},{"id":"42","span":{"begin":695,"end":705},"obj":"Disease"},{"id":"43","span":{"begin":814,"end":822},"obj":"Disease"},{"id":"44","span":{"begin":986,"end":994},"obj":"Disease"},{"id":"45","span":{"begin":1112,"end":1134},"obj":"Disease"}],"attributes":[{"id":"A35","pred":"tao:has_database_id","subj":"35","obj":"Tax:9606"},{"id":"A36","pred":"tao:has_database_id","subj":"36","obj":"MESH:C000657245"},{"id":"A37","pred":"tao:has_database_id","subj":"37","obj":"MESH:C000657245"},{"id":"A38","pred":"tao:has_database_id","subj":"38","obj":"MESH:C000657245"},{"id":"A39","pred":"tao:has_database_id","subj":"39","obj":"MESH:C000657245"},{"id":"A40","pred":"tao:has_database_id","subj":"40","obj":"MESH:D054058"},{"id":"A41","pred":"tao:has_database_id","subj":"41","obj":"MESH:C000657245"},{"id":"A42","pred":"tao:has_database_id","subj":"42","obj":"MESH:D002637"},{"id":"A43","pred":"tao:has_database_id","subj":"43","obj":"MESH:C000657245"},{"id":"A44","pred":"tao:has_database_id","subj":"44","obj":"MESH:C000657245"},{"id":"A45","pred":"tao:has_database_id","subj":"45","obj":"MESH:D003324"},{"subj":"35","pred":"source","obj":"LitCovid-PubTator"},{"subj":"36","pred":"source","obj":"LitCovid-PubTator"},{"subj":"37","pred":"source","obj":"LitCovid-PubTator"},{"subj":"38","pred":"source","obj":"LitCovid-PubTator"},{"subj":"39","pred":"source","obj":"LitCovid-PubTator"},{"subj":"40","pred":"source","obj":"LitCovid-PubTator"},{"subj":"41","pred":"source","obj":"LitCovid-PubTator"},{"subj":"42","pred":"source","obj":"LitCovid-PubTator"},{"subj":"43","pred":"source","obj":"LitCovid-PubTator"},{"subj":"44","pred":"source","obj":"LitCovid-PubTator"},{"subj":"45","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T16","span":{"begin":61,"end":69},"obj":"SP_7"},{"id":"T17","span":{"begin":156,"end":164},"obj":"SP_7"},{"id":"T18","span":{"begin":183,"end":191},"obj":"SP_7"},{"id":"T19","span":{"begin":348,"end":356},"obj":"SP_7"},{"id":"T20","span":{"begin":566,"end":574},"obj":"SP_7"},{"id":"T21","span":{"begin":695,"end":700},"obj":"UBERON:0001443"},{"id":"T22","span":{"begin":814,"end":822},"obj":"SP_7"},{"id":"T23","span":{"begin":986,"end":994},"obj":"SP_7"},{"id":"T24","span":{"begin":1021,"end":1027},"obj":"CHEBI:30212;CHEBI:30212"},{"id":"T25","span":{"begin":1065,"end":1075},"obj":"UBERON:0002349"},{"id":"T26","span":{"begin":1121,"end":1126},"obj":"UBERON:0000948"},{"id":"T67067","span":{"begin":61,"end":69},"obj":"SP_7"},{"id":"T19119","span":{"begin":156,"end":164},"obj":"SP_7"},{"id":"T81906","span":{"begin":183,"end":191},"obj":"SP_7"},{"id":"T85148","span":{"begin":348,"end":356},"obj":"SP_7"},{"id":"T82256","span":{"begin":566,"end":574},"obj":"SP_7"},{"id":"T73215","span":{"begin":695,"end":700},"obj":"UBERON:0001443"},{"id":"T88621","span":{"begin":814,"end":822},"obj":"SP_7"},{"id":"T1733","span":{"begin":986,"end":994},"obj":"SP_7"},{"id":"T39467","span":{"begin":1021,"end":1027},"obj":"CHEBI:30212;CHEBI:30212"},{"id":"T14150","span":{"begin":1065,"end":1075},"obj":"UBERON:0002349"},{"id":"T70329","span":{"begin":1121,"end":1126},"obj":"UBERON:0000948"}],"attributes":[{"subj":"T16","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T17","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T18","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T19","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T20","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T21","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T22","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T23","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T24","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T25","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T26","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T67067","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T19119","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T81906","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T85148","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T82256","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T73215","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T88621","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T1733","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T39467","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T14150","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T70329","pred":"source","obj":"LitCovid-PMC-OGER-BB"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#93abec","default":true},{"id":"LitCovid-PD-UBERON","color":"#c5ec93"},{"id":"LitCovid-PD-MONDO","color":"#ec93df"},{"id":"LitCovid-PD-CLO","color":"#93ecdf"},{"id":"LitCovid-PD-CHEBI","color":"#ecc593"},{"id":"LitCovid-sentences","color":"#ab93ec"},{"id":"LitCovid-PD-HP","color":"#94ec93"},{"id":"LitCovid-PubTator","color":"#ec93ae"},{"id":"LitCovid-PMC-OGER-BB","color":"#93c8ec"}]}]}}