PMC:7417114 / 8819-10433 JSONTXT

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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7417114","sourcedb":"PMC","sourceid":"7417114","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7417114","text":"Table 1. Classification of viruses and the kinase inhibitors showing antiviral activity.\nVirus Baltimore classification Kinase inhibitors showing antiviral activity(potential kinase targets)\nSARS-CoV-2 Group IV, positive sense single-stranded RNA virus imatinib\n(unpublished; preprint: https://www.biorxiv.org/content/10.1101/2020.03.25.008482v2.full)\nabemaciclib, gilteritinib, osimertinib\n(unpublished; preprint:\nhttps://www.biorxiv.org/content/10.1101/2020.03.20.999730v3.full.pdf)\nSARS-CoV Group IV, positive sense single-stranded RNA virus imatinib, dasatinib, nilotinib (ABL2)\n(27) (29)\nMERS-CoV Group IV, positive sense single-stranded RNA virus imatinib, dasatinib (ABL2) (27)\nsaracatinib (LYN, FYN) (33)\nsorafenib (RAF) (68)\nDengue Group IV, positive sense single-stranded RNA virus dasatinib, saracatinib (SRC, FYN) (34) (35) (36)\nsunitinib, erlotinib (AAK1, GAK, AXL, KIT, RET) (46)\nHepatitis C Group IV, positive sense single-stranded RNA virus sunitinib, erlotinib (AAK1, GAK) (41) (42)\ngefitinib, erlotinib (EGFR) (59) ((56) (57)\nWest Nile Group IV, positive sense single-stranded RNA virus sunitinib, erlotinib (46)\nZika Group IV, positive sense single-stranded RNA virus sunitinib, erlotinib (46)\nEbola Group V, negative sense single-stranded RNA virus nilotinib (ABL1) (24)\nInfluenza A Group V, negative sense single-stranded RNA virus alvocidib (CDK9)\nHuman cytomegalovirus Group 1, double-stranded DNA virus gefitinib, erlotinib (EGFR) (59) (57) (56)\nVaccinia Group 1, double-stranded DNA virus imatinib (ABL) (25)\nHerpes simplex type 1 Group 1, double-stranded DNA virus palbociclib (CDK6) 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