PMC:7417114 / 72833-73604 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7417114","sourcedb":"PMC","sourceid":"7417114","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7417114","text":"Respiratory side effects of imatinib include pneumonia (1-10%). Generally, imatinib-induced pulmonary fibrosis and pneumonitis are very infrequently occurring (141) (142), and imatinib-induced pneumonitis develops in a median time of 49 days (143). In dasatinib-treated CML patients, pleural effusion and lung parenchyma changes (ground-glass or alveolar opacities and septal thickening) were described, however resolved after treatment was interrupted (144). The median time between dasatinib treatment initiation and respiratory symptoms was 229 days. In a case study of a dasatinib-treated Japanese patient, pneumonia developed two years after initiation of dasatinib therapy, and drug discontinuation along with corticosteroid therapy greatly improved symptoms 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