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PMC:7417114 / 57974-58439 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T283 424-439 Body_part denotes glucuronic acid http://purl.org/sig/ont/fma/fma82798

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T13272 289-296 Chemical denotes N-oxide http://purl.obolibrary.org/obo/CHEBI_35580
T18122 291-296 Chemical denotes oxide http://purl.obolibrary.org/obo/CHEBI_25741|http://purl.obolibrary.org/obo/CHEBI_29356
T40591 314-316 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T6497 359-368 Chemical denotes masitinib http://purl.obolibrary.org/obo/CHEBI_63450
T63194 381-392 Chemical denotes metabolites http://purl.obolibrary.org/obo/CHEBI_25212
T19833 407-418 Chemical denotes metabolites http://purl.obolibrary.org/obo/CHEBI_25212
T42697 424-439 Chemical denotes glucuronic acid http://purl.obolibrary.org/obo/CHEBI_24298
T32206 435-439 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1586 121-124 Species denotes dog Tax:9615

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T169 222-235 http://purl.obolibrary.org/obo/GO_0070988 denotes demethylation
T170 297-306 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T171 308-326 http://purl.obolibrary.org/obo/GO_0052697 denotes phase II metabolic
T172 308-326 http://purl.obolibrary.org/obo/GO_0051923 denotes phase II metabolic
T173 344-355 http://purl.obolibrary.org/obo/GO_0000746 denotes conjugation

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T482 0-19 Sentence denotes Masitinib (Masivet)
T483 20-465 Sentence denotes (AB Science) Absorption: mean Tmax between 1.7 and 4.7 h; following oral administration of 8.4mg/kg (dog); good absorption/exposure with AUC (0-24 h)=4045 ng*h/mL Phase I metabolic pathways: reduction, demethylation, hydroxylation, oxidative deamination, oxidation and N-oxide formation; phase II metabolic pathways: direct conjugation of masitinib, N-demethyl metabolites and oxidative metabolites with glucuronic acid Information not available