PMC:7417114 / 53651-54016 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7417114","sourcedb":"PMC","sourceid":"7417114","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7417114","text":"The toxicity profile of axitinib in a Phase II clinical trial was consistent with the one reported with the VEGFR-TKI family with grade 3–4 adverse effects, including dyspnea (14.5%) as a respiratory symptom (230);\nin clinical trials, fatal pulmonary embolism was reported in 1/359 patients (\u003c1%) receiving axitinib (Pfizer Labs Patient Information approved by FDA)","divisions":[{"label":"p","span":{"begin":0,"end":214}}],"tracks":[{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T511","span":{"begin":241,"end":259},"obj":"Disease"}],"attributes":[{"id":"A511","pred":"mondo_id","subj":"T511","obj":"http://purl.obolibrary.org/obo/MONDO_0005279"},{"subj":"T511","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T610","span":{"begin":36,"end":37},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T611","span":{"begin":136,"end":139},"obj":"http://purl.obolibrary.org/obo/CLO_0001302"},{"id":"T612","span":{"begin":186,"end":187},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"attributes":[{"subj":"T610","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T611","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T612","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T73177","span":{"begin":24,"end":32},"obj":"Chemical"},{"id":"T47340","span":{"begin":44,"end":46},"obj":"Chemical"},{"id":"T79503","span":{"begin":307,"end":315},"obj":"Chemical"}],"attributes":[{"id":"A56857","pred":"chebi_id","subj":"T73177","obj":"http://purl.obolibrary.org/obo/CHEBI_66910"},{"id":"A53342","pred":"chebi_id","subj":"T47340","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"},{"id":"A80107","pred":"chebi_id","subj":"T79503","obj":"http://purl.obolibrary.org/obo/CHEBI_66910"},{"subj":"T73177","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T47340","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T79503","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"1518","span":{"begin":108,"end":113},"obj":"Gene"},{"id":"1577","span":{"begin":282,"end":290},"obj":"Species"},{"id":"1578","span":{"begin":329,"end":336},"obj":"Species"}],"attributes":[{"id":"A1518","pred":"tao:has_database_id","subj":"1518","obj":"Gene:3791"},{"id":"A1577","pred":"tao:has_database_id","subj":"1577","obj":"Tax:9606"},{"id":"A1578","pred":"tao:has_database_id","subj":"1578","obj":"Tax:9606"},{"subj":"1518","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1577","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1578","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T150","span":{"begin":167,"end":174},"obj":"Phenotype"},{"id":"T151","span":{"begin":241,"end":259},"obj":"Phenotype"}],"attributes":[{"id":"A150","pred":"hp_id","subj":"T150","obj":"http://purl.obolibrary.org/obo/HP_0002094"},{"id":"A151","pred":"hp_id","subj":"T151","obj":"http://purl.obolibrary.org/obo/HP_0002204"},{"subj":"T150","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T151","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T443","span":{"begin":215,"end":365},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T443","pred":"source","obj":"LitCovid-sentences"}]},{"project":"2_test","denotations":[{"id":"32778962-17959415-84130744","span":{"begin":209,"end":212},"obj":"17959415"}],"attributes":[{"subj":"32778962-17959415-84130744","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-MONDO","color":"#e7ec93","default":true},{"id":"LitCovid-PD-CLO","color":"#d793ec"},{"id":"LitCovid-PD-CHEBI","color":"#93ecbd"},{"id":"LitCovid-PubTator","color":"#eca393"},{"id":"LitCovid-PD-HP","color":"#939dec"},{"id":"LitCovid-sentences","color":"#b7ec93"},{"id":"2_test","color":"#ec93d1"}]}]}}