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PMC:7417114 / 36639-37254 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T199 287-295 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T200 420-428 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T393 310-318 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T394 341-357 Disease denotes virus infections http://purl.obolibrary.org/obo/MONDO_0005108
T395 388-404 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T396 416-419 Disease denotes ABL http://purl.obolibrary.org/obo/MONDO_0008692

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T465 204-211 http://purl.obolibrary.org/obo/CLO_0009985 denotes focused
T466 230-231 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T467 341-346 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T468 469-472 http://purl.obolibrary.org/obo/CLO_0037126 denotes GAK
T469 489-492 http://purl.obolibrary.org/obo/CLO_0009132 denotes SRC

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T325 260-270 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T326 287-295 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T327 416-419 Chemical denotes ABL http://purl.obolibrary.org/obo/CHEBI_30805
T328 420-428 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T329 553-563 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T330 567-576 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1304 416-419 Gene denotes ABL Gene:25
1305 430-434 Gene denotes AAK1 Gene:22848
1306 436-439 Gene denotes AXL Gene:558
1307 441-445 Gene denotes CDK6 Gene:1021
1308 447-451 Gene denotes CDK9 Gene:1025
1309 453-456 Gene denotes CSK Gene:1445
1310 458-462 Gene denotes EGFR Gene:1956
1311 464-467 Gene denotes FYN Gene:2534
1312 469-472 Gene denotes GAK Gene:2580
1313 474-477 Gene denotes KIT Gene:3815
1314 479-482 Gene denotes LYN Gene:4067
1315 484-487 Gene denotes RET Gene:5979
1316 310-318 Species denotes SARS-CoV Tax:694009
1317 320-328 Species denotes MERS-CoV Tax:1335626
1318 341-357 Disease denotes virus infections MESH:D001102
1319 388-404 Disease denotes viral infections MESH:D001102

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T143 253-270 http://purl.obolibrary.org/obo/GO_0033673 denotes kinase inhibitors
T144 388-404 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T145 458-462 http://purl.obolibrary.org/obo/GO_0005006 denotes EGFR
T146 546-563 http://purl.obolibrary.org/obo/GO_0033673 denotes kinase inhibitors

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T284 0-520 Sentence denotes Using KINOMEscan biochemical kinase profiling assay data from the Harvard Medical School Library of Integrated Network-based Cellular Signatures (LINCS) (72) and data derived from the ChEMBL database, we focused on the ability of a list of FDA-approved kinase inhibitors to target those proteins implicated in SARS-CoV, MERS-CoV and related virus infections, as well as several unrelated viral infections, including ABL proteins, AAK1, AXL, CDK6, CDK9, CSK, EGFR, FYN, GAK, KIT, LYN, RET, SRC, and YES (Table 2, Fig. 3).
T285 521-530 Sentence denotes Figure 3.
T286 531-615 Sentence denotes Repurposing of kinase inhibitors as antiviral therapies and for respiratory benefit.

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T2198 40-122 CHEBI:35222;CHEBI:35222 denotes iling assay data from the Harvard Medical School Library of Integrated Network-bas