PMC:7414629 / 9335-12650
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T85 | 1356-1368 | Body_part | denotes | facial nerve | http://purl.org/sig/ont/fma/fma50868 |
T86 | 1722-1734 | Body_part | denotes | Facial nerve | http://purl.org/sig/ont/fma/fma50868 |
T87 | 1842-1847 | Body_part | denotes | nerve | http://purl.org/sig/ont/fma/fma65132 |
T88 | 1915-1918 | Body_part | denotes | CSF | http://purl.org/sig/ont/fma/fma20935 |
T89 | 1981-1984 | Body_part | denotes | CSF | http://purl.org/sig/ont/fma/fma20935 |
T90 | 2275-2280 | Body_part | denotes | Nerve | http://purl.org/sig/ont/fma/fma65132 |
T91 | 2694-2697 | Body_part | denotes | CNS | http://purl.org/sig/ont/fma/fma55675 |
T92 | 2783-2801 | Body_part | denotes | respiratory system | http://purl.org/sig/ont/fma/fma7158 |
T93 | 2911-2936 | Body_part | denotes | peripheral nervous system | http://purl.org/sig/ont/fma/fma9903 |
T94 | 3087-3090 | Body_part | denotes | CSF | http://purl.org/sig/ont/fma/fma20935 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T55 | 1356-1368 | Body_part | denotes | facial nerve | http://purl.obolibrary.org/obo/UBERON_0001647 |
T56 | 1363-1368 | Body_part | denotes | nerve | http://purl.obolibrary.org/obo/UBERON_0001021 |
T57 | 1722-1734 | Body_part | denotes | Facial nerve | http://purl.obolibrary.org/obo/UBERON_0001647 |
T58 | 1729-1734 | Body_part | denotes | nerve | http://purl.obolibrary.org/obo/UBERON_0001021 |
T59 | 1842-1847 | Body_part | denotes | nerve | http://purl.obolibrary.org/obo/UBERON_0001021 |
T60 | 2275-2280 | Body_part | denotes | Nerve | http://purl.obolibrary.org/obo/UBERON_0001021 |
T61 | 2694-2697 | Body_part | denotes | CNS | http://purl.obolibrary.org/obo/UBERON_0001017 |
T62 | 2783-2801 | Body_part | denotes | respiratory system | http://purl.obolibrary.org/obo/UBERON_0001004 |
T63 | 2911-2936 | Body_part | denotes | peripheral nervous system | http://purl.obolibrary.org/obo/UBERON_0000010 |
T64 | 2922-2936 | Body_part | denotes | nervous system | http://purl.obolibrary.org/obo/UBERON_0001016 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T55 | 95-103 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T56 | 106-115 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T57 | 120-123 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T58 | 229-232 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T59 | 259-267 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T60 | 270-279 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T61 | 392-400 | Disease | denotes | COVID 19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T62 | 515-518 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T63 | 537-540 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T64 | 552-560 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T65 | 563-573 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
T66 | 691-699 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T67 | 795-798 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T68 | 896-904 | Disease | denotes | COVID 19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T69 | 1036-1039 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T70 | 1090-1098 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T71 | 1101-1110 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T72 | 1122-1125 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T73 | 1356-1374 | Disease | denotes | facial nerve palsy | http://purl.obolibrary.org/obo/MONDO_0005665 |
T74 | 1369-1374 | Disease | denotes | palsy | http://purl.obolibrary.org/obo/MONDO_0006496 |
T75 | 1750-1753 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T76 | 1863-1866 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T77 | 1960-1968 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T78 | 2165-2168 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T79 | 2736-2739 | Disease | denotes | GBS | http://purl.obolibrary.org/obo/MONDO_0016218 |
T80 | 2827-2835 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T81 | 3066-3074 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T143 | 40-41 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T144 | 63-65 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
T145 | 196-197 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T146 | 311-312 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T147 | 715-716 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T148 | 1142-1143 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T149 | 1241-1242 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T150 | 1274-1275 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T151 | 1363-1368 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | nerve |
T152 | 1398-1401 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T153 | 1450-1453 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 3/5 |
T154 | 1491-1492 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T155 | 1586-1587 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T156 | 1658-1659 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T157 | 1729-1734 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | nerve |
T158 | 1757-1758 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T159 | 1777-1779 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
T160 | 1822-1823 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T161 | 1842-1847 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | nerve |
T162 | 1906-1908 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
T163 | 2258-2264 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tested |
T164 | 2275-2280 | http://purl.obolibrary.org/obo/UBERON_0001021 | denotes | Nerve |
T165 | 2554-2555 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T166 | 2572-2573 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T167 | 2651-2654 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T168 | 2662-2669 | http://purl.obolibrary.org/obo/CLO_0009985 | denotes | focused |
T169 | 2694-2697 | http://www.ebi.ac.uk/efo/EFO_0000302 | denotes | CNS |
T170 | 2694-2697 | http://www.ebi.ac.uk/efo/EFO_0000908 | denotes | CNS |
T171 | 2694-2697 | http://purl.obolibrary.org/obo/UBERON_0001017 | denotes | CNS |
T172 | 2750-2751 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T173 | 2783-2801 | http://purl.obolibrary.org/obo/UBERON_0001004 | denotes | respiratory system |
T174 | 2847-2853 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tested |
T175 | 2911-2936 | http://purl.obolibrary.org/obo/UBERON_0000010 | denotes | peripheral nervous system |
T176 | 2911-2936 | http://www.ebi.ac.uk/efo/EFO_0000891 | denotes | peripheral nervous system |
T177 | 3055-3056 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T178 | 3110-3111 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
213 | 588-596 | Species | denotes | patients | Tax:9606 |
214 | 100-115 | Disease | denotes | CoV-2 infection | MESH:C000657245 |
215 | 259-279 | Disease | denotes | SARS-CoV-2 infection | MESH:C000657245 |
216 | 392-400 | Disease | denotes | COVID 19 | MESH:C000657245 |
217 | 417-437 | Disease | denotes | respiratory symptoms | MESH:D012818 |
218 | 552-573 | Disease | denotes | SARS-CoV-2 infections | MESH:C000657245 |
219 | 607-627 | Disease | denotes | respiratory symptoms | MESH:D012818 |
220 | 691-699 | Disease | denotes | COVID-19 | MESH:C000657245 |
221 | 823-843 | Disease | denotes | respiratory symptoms | MESH:D012818 |
222 | 896-904 | Disease | denotes | COVID 19 | MESH:C000657245 |
223 | 1090-1110 | Disease | denotes | SARS-CoV-2 infection | MESH:C000657245 |
231 | 1637-1645 | Species | denotes | patients | Tax:9606 |
232 | 1704-1712 | Species | denotes | patients | Tax:9606 |
233 | 1363-1374 | Disease | denotes | nerve palsy | MESH:D010243 |
234 | 1493-1508 | Disease | denotes | facial diplegia | MESH:C531747 |
235 | 1525-1540 | Disease | denotes | facial weakness | MESH:D018908 |
236 | 1681-1696 | Disease | denotes | facial diplegia | MESH:C531747 |
237 | 1722-1746 | Disease | denotes | Facial nerve involvement | MESH:D005155 |
241 | 1960-1970 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
242 | 2006-2013 | Species | denotes | patient | Tax:9606 |
243 | 2048-2056 | Species | denotes | patients | Tax:9606 |
250 | 2827-2837 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
251 | 2854-2862 | Species | denotes | patients | Tax:9606 |
252 | 3066-3076 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
253 | 2765-2801 | Disease | denotes | impairment of the respiratory system | MESH:D012131 |
254 | 3122-3137 | Disease | denotes | facial weakness | MESH:D018908 |
255 | 3169-3177 | Disease | denotes | diplegia | MESH:D002547 |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T22 | 2120-2122 | Chemical | denotes | GM | http://purl.obolibrary.org/obo/CHEBI_74120 |
T23 | 2127-2131 | Chemical | denotes | GQ1b | http://purl.obolibrary.org/obo/CHEBI_27515 |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T33 | 1356-1374 | Phenotype | denotes | facial nerve palsy | http://purl.obolibrary.org/obo/HP_0010628 |
T34 | 1493-1508 | Phenotype | denotes | facial diplegia | http://purl.obolibrary.org/obo/HP_0001349 |
T35 | 1525-1540 | Phenotype | denotes | facial weakness | http://purl.obolibrary.org/obo/HP_0030319 |
T36 | 1681-1696 | Phenotype | denotes | facial diplegia | http://purl.obolibrary.org/obo/HP_0001349 |
T37 | 3112-3137 | Phenotype | denotes | bilateral facial weakness | http://purl.obolibrary.org/obo/HP_0001349 |
T38 | 3162-3177 | Phenotype | denotes | facial diplegia | http://purl.obolibrary.org/obo/HP_0001349 |
LitCovid-PD-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue | glyco_epitope_db_id |
---|---|---|---|---|---|
T3 | 2127-2131 | GlycoEpitope | denotes | GQ1b | http://www.glycoepitope.jp/epitopes/EP0069 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T83 | 0-10 | Sentence | denotes | Discussion |
T84 | 11-124 | Sentence | denotes | Only one case series [8] and a few case reports [9, 11] show an association between SARS-CoV-2 infection and GBS. |
T85 | 125-233 | Sentence | denotes | The presented well-documented case report shows all characteristics of a typical, but severe, course of GBS. |
T86 | 234-357 | Sentence | denotes | The association with the SARS-CoV-2 infection in the present case is without a doubt because of the strict time connection. |
T87 | 358-456 | Sentence | denotes | The clinical course regarding the COVID 19 disease and the respiratory symptoms was uncomplicated. |
T88 | 457-519 | Sentence | denotes | The main complaint was the neurological complication with GBS. |
T89 | 520-685 | Sentence | denotes | Severe course of GBS-associated SARS-CoV-2 infections occur also in patients with mild respiratory symptoms, but must be taken into account with seriously ill cases. |
T90 | 686-788 | Sentence | denotes | With COVID-19 disease due to a general impairment, the neurological symptoms can be easily overlooked. |
T91 | 789-905 | Sentence | denotes | Since GBS can cause or exacerbate respiratory symptoms, it should take into account the suspect courses of COVID 19. |
T92 | 906-1040 | Sentence | denotes | It would be helpful if clinical, paraclinical, or electrophysiological findings were found that would facilitate the diagnosis of GBS. |
T93 | 1041-1169 | Sentence | denotes | To date, the previously described courses of the SARS-CoV-2 infection-associated GBS do not describe a special clinical pattern. |
T94 | 1170-1273 | Sentence | denotes | To date, available references summarizing the following points include a total of nine published cases. |
T95 | 1274-1375 | Sentence | denotes | A remarkable clinical pattern in our case was that there was bilateral peripheral facial nerve palsy. |
T96 | 1376-1558 | Sentence | denotes | This clinical symptom has been reported in one other case report [10] and 3/5 cases in the Italian series reported a facial diplegia in one case and facial weakness in two cases [8]. |
T97 | 1559-1721 | Sentence | denotes | Therefore, we can describe a bilateral facial involvement in five out of nine patients (55.5%) and a documented bilateral facial diplegia in 3/9 patients (33,3%). |
T98 | 1722-1789 | Sentence | denotes | Facial nerve involvement in GBS is a common finding in 27–50% [12]. |
T99 | 1790-1867 | Sentence | denotes | There are no data available for a bilateral seventh nerve involvement in GBS. |
T100 | 1868-1910 | Sentence | denotes | Estimated data reported up to 12–25% [11]. |
T101 | 1911-1955 | Sentence | denotes | The CSF parameters show no specific pattern. |
T102 | 1956-2091 | Sentence | denotes | The SARS-CoV-2 RT-PCR in CSF was performed in our patient and in the Italian series of five patients [8] and was negative in all cases. |
T103 | 2092-2178 | Sentence | denotes | Antiganglioside antibodies (GM 1-, GQ1b-antibodies) may indicate special GBS subtypes. |
T104 | 2179-2274 | Sentence | denotes | They were analyzed in our case and three out of five in the Italian series [8] tested negative. |
T105 | 2275-2367 | Sentence | denotes | Nerve conduction studies have been performed in our case and two other case reports [9, 10]. |
T106 | 2368-2434 | Sentence | denotes | An axonal affection pattern is reported in two out of three cases. |
T107 | 2435-2528 | Sentence | denotes | Except for the presented case, the clinical course of the other cases is not well documented. |
T108 | 2529-2632 | Sentence | denotes | So the data do not allow a discussion over a prognostic value of the present electrophysiological data. |
T109 | 2633-2710 | Sentence | denotes | So far, attention has mostly focused on complications of the CNS involvement. |
T110 | 2711-2937 | Sentence | denotes | Taking into account that GBS can cause a considerable impairment of the respiratory system, clinicians dealing with SARS-CoV-2 positive-tested patients should have to pay attention to symptoms of the peripheral nervous system. |
T111 | 2938-3091 | Sentence | denotes | As far as we know from these few reported cases, there seems to be no association with antiganglioside antibodies or a positive SARS-CoV-2 RT-PCR in CSF. |
T112 | 3092-3199 | Sentence | denotes | The occurrence of a bilateral facial weakness or bilateral peripheral facial diplegia should be emphasized. |
T113 | 3200-3315 | Sentence | denotes | This finding and the appearance of specific electrophysiological pattern should be shown in further investigations. |
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T139 | 2275-2280 | UBERON:0006134 | denotes | Nerve |
T140 | 2281-2291 | GO:0007399 | denotes | conduction |
T155 | 3151-3161 | UBERON:0001021 | denotes | peripheral |
T157 | 2974-2980 | UBERON:0001456 | denotes | orted |
T158 | 3006-3012 | UBERON:0001456 | denotes | o asso |
T159 | 3079-3085 | UBERON:0001456 | denotes | -PCR i |
T160 | 3162-3168 | UBERON:0001456 | denotes | facial |
T171 | 2694-2697 | UBERON:0001017 | denotes | CNS |
T172 | 2783-2801 | UBERON:0001004 | denotes | respiratory system |
T173 | 2827-2837 | SP_7 | denotes | SARS-CoV-2 |
T174 | 2911-2936 | UBERON:0000010 | denotes | peripheral nervous system |
T175 | 3041-3051 | GO:0042571 | denotes | antibodies |
T176 | 3066-3076 | SP_7 | denotes | SARS-CoV-2 |
T177 | 3122-3128 | UBERON:0001456 | denotes | facial |
T178 | 3162-3168 | UBERON:0001456 | denotes | facial |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32770414-32302082-63220883 | 33-34 | 32302082 | denotes | 8 |
32770414-32312628-63220884 | 60-61 | 32312628 | denotes | 9 |
32770414-32313807-63220885 | 63-65 | 32313807 | denotes | 11 |
32770414-32302082-63220886 | 1555-1556 | 32302082 | denotes | 8 |
32770414-32313807-63220887 | 1906-1908 | 32313807 | denotes | 11 |
32770414-32302082-63220888 | 2058-2059 | 32302082 | denotes | 8 |
32770414-32302082-63220889 | 2255-2256 | 32302082 | denotes | 8 |
32770414-32312628-63220890 | 2360-2361 | 32312628 | denotes | 9 |