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PMC:7408073 / 985-3875 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T42134 821-832 Body_part denotes eosinophils http://purl.org/sig/ont/fma/fma62861
T20834 1077-1085 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T67033 1109-1113 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T79726 2388-2398 Body_part denotes eosinophil http://purl.org/sig/ont/fma/fma62861
T26227 2465-2475 Body_part denotes eosinophil http://purl.org/sig/ont/fma/fma62861
T2518 2810-2816 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T6 2810-2816 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
88 1109-1114 Gene denotes IL-1β Gene:3552
89 1116-1120 Gene denotes IL-6 Gene:3569
90 1122-1126 Gene denotes IL-8 Gene:3576
91 1128-1133 Gene denotes IL-10 Gene:3586
92 1138-1142 Gene denotes TNFα Gene:7124
93 26-73 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
94 75-85 Species denotes SARS-CoV-2 Tax:2697049
95 275-283 Species denotes patients Tax:9606
96 694-702 Species denotes patients Tax:9606
97 726-734 Species denotes patients Tax:9606
98 1409-1417 Species denotes patients Tax:9606
99 1467-1475 Species denotes patients Tax:9606
100 1832-1839 Species denotes patient Tax:9606
101 1872-1880 Species denotes patients Tax:9606
102 2328-2336 Species denotes patients Tax:9606
103 2621-2629 Species denotes patients Tax:9606
104 2825-2833 Species denotes patients Tax:9606
105 2881-2889 Species denotes patients Tax:9606
106 2338-2341 Gene denotes Th2 Gene:15111
107 322-328 Chemical denotes oxygen MESH:D010100
108 380-391 Chemical denotes chloroquine MESH:D002738
109 397-407 Chemical denotes macrolides MESH:D018942
110 87-96 Disease denotes infection MESH:D007239
111 117-125 Disease denotes COVID-19 MESH:C000657245
112 255-263 Disease denotes COVID-19 MESH:C000657245
113 264-273 Disease denotes infection MESH:D007239
114 441-461 Disease denotes SARS-CoV-2 infection MESH:C000657245
115 564-590 Disease denotes acute respiratory syndrome MESH:D012120
116 613-618 Disease denotes death MESH:D003643
117 743-772 Disease denotes lymphopaenia and eosinopaenia
118 850-862 Disease denotes eosinopaenia
119 963-989 Disease denotes cardiac dysfunction/injury MESH:D006331
120 991-1019 Disease denotes respiratory distress/illness MESH:D012140
121 1021-1061 Disease denotes coagulopathy, hypoproteinaemia, acidosis MESH:D000138
122 1063-1070 Disease denotes hypoxia MESH:D000860
123 1178-1190 Disease denotes hypertension MESH:D006973
124 1271-1285 Disease denotes severe disease MESH:D045169
125 1349-1355 Disease denotes asthma MESH:D001249
126 1400-1408 Disease denotes infected MESH:D007239
127 1458-1466 Disease denotes allergic MESH:D004342
128 1570-1576 Disease denotes asthma MESH:D001249
129 1638-1654 Disease denotes Viral infections MESH:D001102
130 1684-1700 Disease denotes allergic disease MESH:D004342
131 2011-2031 Disease denotes hypertensive disease MESH:D006973
132 2122-2137 Disease denotes virus infection MESH:D001102
133 2182-2194 Disease denotes hypertension MESH:D006973
134 2319-2327 Disease denotes infected MESH:D007239
135 2351-2368 Disease denotes allergic diseases MESH:D004342
136 2525-2537 Disease denotes hypertensive MESH:D006973
137 2599-2607 Disease denotes COVID-19 MESH:C000657245
138 2645-2666 Disease denotes chronic renal disease MESH:D051436
139 2802-2824 Disease denotes chronic kidney disease MESH:D051436
140 2858-2866 Disease denotes COVID-19 MESH:C000657245
141 2874-2880 Disease denotes asthma MESH:D001249

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T7 26-73 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T8 26-59 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T9 75-83 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T10 75-79 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T11 87-96 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T12 117-125 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T13 255-263 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T14 264-273 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T15 441-449 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T16 441-445 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T17 452-461 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T18 557-590 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T19 592-596 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T20 930-934 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T21 983-989 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T22 1021-1033 Disease denotes coagulopathy http://purl.obolibrary.org/obo/MONDO_0001531
T23 1053-1061 Disease denotes acidosis http://purl.obolibrary.org/obo/MONDO_0006022
T24 1178-1190 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T25 1349-1355 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T26 1458-1466 Disease denotes allergic http://purl.obolibrary.org/obo/MONDO_0004980
T27 1570-1576 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T28 1638-1654 Disease denotes Viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T29 1684-1700 Disease denotes allergic disease http://purl.obolibrary.org/obo/MONDO_0005271
T30 1684-1692 Disease denotes allergic http://purl.obolibrary.org/obo/MONDO_0004980
T31 1984-1988 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T32 2011-2031 Disease denotes hypertensive disease http://purl.obolibrary.org/obo/MONDO_0005044
T33 2122-2137 Disease denotes virus infection http://purl.obolibrary.org/obo/MONDO_0005108
T34 2128-2137 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T35 2182-2194 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T36 2351-2368 Disease denotes allergic diseases http://purl.obolibrary.org/obo/MONDO_0005271
T37 2351-2359 Disease denotes allergic http://purl.obolibrary.org/obo/MONDO_0004980
T38 2442-2446 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T39 2599-2607 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T40 2645-2666 Disease denotes chronic renal disease http://purl.obolibrary.org/obo/MONDO_0005300
T41 2653-2666 Disease denotes renal disease http://purl.obolibrary.org/obo/MONDO_0002118|http://purl.obolibrary.org/obo/MONDO_0005240
T43 2802-2824 Disease denotes chronic kidney disease http://purl.obolibrary.org/obo/MONDO_0005300
T44 2810-2824 Disease denotes kidney disease http://purl.obolibrary.org/obo/MONDO_0001343|http://purl.obolibrary.org/obo/MONDO_0005240
T46 2858-2866 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T47 2874-2880 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T92165 797-806 http://www.ebi.ac.uk/efo/EFO_0000876 denotes extremely
T23402 870-871 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T30677 1075-1076 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T96031 1122-1126 http://purl.obolibrary.org/obo/CLO_0053704 denotes IL-8
T99826 1396-1399 http://purl.obolibrary.org/obo/CLO_0001414 denotes 548
T43843 1970-1975 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T60553 2094-2095 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T56639 2122-2127 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T28761 2224-2226 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T99781 2266-2268 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T70533 2416-2417 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T72708 2810-2816 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T15863 2810-2816 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T37184 2810-2816 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T15 322-328 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T16 350-365 Chemical denotes glucocorticoids http://purl.obolibrary.org/obo/CHEBI_24261
T17 380-391 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T18 397-407 Chemical denotes macrolides http://purl.obolibrary.org/obo/CHEBI_25106
T19 893-902 Chemical denotes biomarker http://purl.obolibrary.org/obo/CHEBI_59163
T20 1109-1111 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T22 1116-1118 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T24 1122-1124 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T26 1128-1130 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T28 2052-2068 Chemical denotes antihypertensive http://purl.obolibrary.org/obo/CHEBI_35674

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T46890 640-645 http://purl.obolibrary.org/obo/GO_0007568 denotes Aging
T87124 1638-1654 http://purl.obolibrary.org/obo/GO_0016032 denotes Viral infections

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T7 0-2 Sentence denotes 1.
T8 3-15 Sentence denotes Introduction
T9 16-193 Sentence denotes The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is the cause of the COVID-19 pandemic, for which there is currently no specific pharmacotherapy.
T10 194-436 Sentence denotes In the intensive care unit, depending on the severity of the COVID-19 infection, patients might receive supportive care such as oxygen supply, interferons, glucocorticoids, anti-virals, chloroquine, and macrolides given as deemed appropriate.
T11 437-639 Sentence denotes The SARS-CoV-2 infection produces either non-severe or severe symptoms and, in the latter case, it may precipitate into severe acute respiratory syndrome (SARS) and ultimately death [1,2,3,4,5,6,7,8,9].
T12 640-720 Sentence denotes Aging and different comorbidities are associated with patients’ critical status.
T13 721-907 Sentence denotes Most patients display lymphopaenia and eosinopaenia, and critical ones show extremely low levels of eosinophils, suggesting that eosinopaenia may be a potential diagnostic biomarker [1].
T14 908-1163 Sentence denotes Most serious cases of SARS are closely associated with cardiac dysfunction/injury, respiratory distress/illness, coagulopathy, hypoproteinaemia, acidosis, hypoxia and a cytokine storm mainly involving IL-1β, IL-6, IL-8, IL-10 and TNFα [1,2,3,4,5,6,7,8,9].
T15 1164-1637 Sentence denotes For instance, hypertension, an age-related disease, is the most common comorbidity (15–31% up to 24–58% in severe disease cases according to clinical reports), while only five cases of asthma (0.9%) were identified in one report of 548 infected patients in Wuhan [6], but no other asthmatic or allergic patients were described in other reports [1,2,3,4,5,7,8,9], considering that the overall prevalence of asthma is estimated to be 6.4% in Wuhan [6] and ~ 4% in China [10].
T16 1638-1803 Sentence denotes Viral infections usually increase the risk of allergic disease exacerbation [1]; however, the reported data seem to suggest that, in this case, the opposite is true.
T17 1804-2270 Sentence denotes Indeed, in more than 72.000 patient cohorts examined, the number of patients defined as asthmatic was low (5), which suggests that asthmatics might be protected from virus-induced SARS, whereas pre-existing hypertensive disease and/or pre-existing antihypertensive treatments may represent a risk factor for increased virus infection, considering that the overall prevalence of hypertension in Chinese adult population ≥18 years of age is estimated to be ~ 23% [11].
T18 2271-2573 Sentence denotes Therefore, according to the clinical picture of infected patients, Th2-mediated allergic diseases (usually with high eosinophil counts) may play a protective role against SARS (usually with low eosinophil counts), while yet unknown mechanisms related to hypertensive conditions may exacerbate symptoms.
T19 2574-2890 Sentence denotes To complete the picture, COVID-19 hospitalized patients suffering from chronic renal disease were usually low (0-3%) [1,2,3,4,5,6,7,8,9] if compared with the prevalence of the disease in China (10.2-11.3%) [12], suggesting that chronic kidney disease patients might be protected from COVID-19 as for asthma patients.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T2 991-1011 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T3 1021-1033 Phenotype denotes coagulopathy http://purl.obolibrary.org/obo/HP_0003256
T4 1053-1061 Phenotype denotes acidosis http://purl.obolibrary.org/obo/HP_0001941
T5 1063-1070 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T6 1077-1091 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T7 1178-1190 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T8 1349-1355 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T9 1570-1576 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T10 2182-2194 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T11 2802-2824 Phenotype denotes chronic kidney disease http://purl.obolibrary.org/obo/HP_0012622
T12 2874-2880 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099

2_test

Id Subject Object Predicate Lexical cue
32708755-32077115-20678617 620-621 32077115 denotes 1
32708755-32161940-20678618 622-623 32161940 denotes 2
32708755-32171076-20678619 624-625 32171076 denotes 3
32708755-32109013-20678620 628-629 32109013 denotes 5
32708755-32294485-20678621 630-631 32294485 denotes 6
32708755-32091533-20678622 632-633 32091533 denotes 7
32708755-31986264-20678623 634-635 31986264 denotes 8
32708755-32297671-20678624 636-637 32297671 denotes 9
32708755-32077115-20678625 904-905 32077115 denotes 1
32708755-32077115-20678626 1144-1145 32077115 denotes 1
32708755-32161940-20678627 1146-1147 32161940 denotes 2
32708755-32171076-20678628 1148-1149 32171076 denotes 3
32708755-32109013-20678629 1152-1153 32109013 denotes 5
32708755-32294485-20678630 1154-1155 32294485 denotes 6
32708755-32091533-20678631 1156-1157 32091533 denotes 7
32708755-31986264-20678632 1158-1159 31986264 denotes 8
32708755-32297671-20678633 1160-1161 32297671 denotes 9
32708755-32294485-20678634 1428-1429 32294485 denotes 6
32708755-32077115-20678635 1509-1510 32077115 denotes 1
32708755-32161940-20678636 1511-1512 32161940 denotes 2
32708755-32171076-20678637 1513-1514 32171076 denotes 3
32708755-32109013-20678638 1517-1518 32109013 denotes 5
32708755-32091533-20678639 1519-1520 32091533 denotes 7
32708755-31986264-20678640 1521-1522 31986264 denotes 8
32708755-32297671-20678641 1523-1524 32297671 denotes 9
32708755-32294485-20678642 1611-1612 32294485 denotes 6
32708755-31230828-20678643 1633-1635 31230828 denotes 10
32708755-32077115-20678644 1715-1716 32077115 denotes 1
32708755-29449338-20678645 2266-2268 29449338 denotes 11
32708755-32077115-20678646 2692-2693 32077115 denotes 1
32708755-32161940-20678647 2694-2695 32161940 denotes 2
32708755-32171076-20678648 2696-2697 32171076 denotes 3
32708755-32109013-20678649 2700-2701 32109013 denotes 5
32708755-32294485-20678650 2702-2703 32294485 denotes 6
32708755-32091533-20678651 2704-2705 32091533 denotes 7
32708755-31986264-20678652 2706-2707 31986264 denotes 8
32708755-32297671-20678653 2708-2709 32297671 denotes 9
32708755-22386035-20678654 2781-2783 22386035 denotes 12