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PMC:7408073 / 985-112683 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 99139-99154 Body_part denotes digestive tract http://purl.org/sig/ont/fma/fma317863
T2 99183-99188 Body_part denotes bowel http://purl.org/sig/ont/fma/fma7199
T3 99644-99649 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T4 99700-99708 Body_part denotes capsules http://purl.org/sig/ont/fma/fma85272
T5 99844-99852 Body_part denotes capsules http://purl.org/sig/ont/fma/fma85272
T6 100077-100081 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T7 100238-100242 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T8 100310-100327 Body_part denotes respiratory tract http://purl.org/sig/ont/fma/fma265130
T9 101333-101337 Body_part denotes face http://purl.org/sig/ont/fma/fma24728
T10 101371-101375 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T11 101755-101760 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T12 101761-101765 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T13 101766-101771 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T14 101772-101781 Body_part denotes intestine http://purl.org/sig/ont/fma/fma7199
T15 101782-101788 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T16 101789-101802 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T17 101803-101808 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T18 101950-101955 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T19 102046-102052 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T20 102197-102201 Body_part denotes face http://purl.org/sig/ont/fma/fma24728
T21 102534-102538 Body_part denotes sole http://purl.org/sig/ont/fma/fma25000
T22 102769-102773 Body_part denotes face http://purl.org/sig/ont/fma/fma24728
T23 103947-103959 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T24 103947-103951 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T25 104696-104704 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T26 104792-104807 Body_part denotes coronary artery http://purl.org/sig/ont/fma/fma49893
T27 105029-105034 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T28 105875-105897 Body_part denotes gastrointestinal tract http://purl.org/sig/ont/fma/fma71132
T29 106092-106098 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T30 106125-106135 Body_part denotes intestinal http://purl.org/sig/ont/fma/fma7199
T31 106849-106854 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T32 107222-107226 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T33 107227-107233 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T34 108352-108356 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T35 109150-109156 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T36 109938-109943 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T37 109954-109964 Body_part denotes eosinophil http://purl.org/sig/ont/fma/fma62861
T38 110122-110138 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T39 110133-110138 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T42134 821-832 Body_part denotes eosinophils http://purl.org/sig/ont/fma/fma62861
T20834 1077-1085 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T67033 1109-1113 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T79726 2388-2398 Body_part denotes eosinophil http://purl.org/sig/ont/fma/fma62861
T26227 2465-2475 Body_part denotes eosinophil http://purl.org/sig/ont/fma/fma62861
T2518 2810-2816 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T21234 3030-3037 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T2030 3096-3101 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T47742 3147-3163 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T6114 3158-3163 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T36553 3177-3194 Body_part denotes endothelial cells http://purl.org/sig/ont/fma/fma66772
T93384 3189-3194 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T78860 3264-3268 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T18627 3326-3333 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T66005 3370-3377 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T74461 3427-3431 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T26291 3459-3463 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T89422 3464-3469 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T39415 3627-3639 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T6412 3627-3631 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T55226 3656-3665 Body_part denotes epithelia http://purl.org/sig/ont/fma/fma9639
T86589 3747-3754 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T74128 4013-4020 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T10664 4042-4046 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T4715 4070-4079 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T30405 4086-4095 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T89383 4260-4269 Body_part denotes epithelia http://purl.org/sig/ont/fma/fma9639
T34441 4370-4377 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T53940 4402-4409 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T48489 4443-4448 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T22482 4504-4511 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T54868 4883-4890 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T83587 4913-4918 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T57345 5550-5557 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T54062 5644-5659 Body_part denotes protein complex http://purl.org/sig/ont/fma/fma67906
T62408 5998-6002 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T81532 6041-6046 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T50862 6320-6340 Body_part denotes bronchial epithelium http://purl.org/sig/ont/fma/fma67782
T15477 6330-6340 Body_part denotes epithelium http://purl.org/sig/ont/fma/fma9639
T22792 6438-6454 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T24903 6449-6454 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T67719 6625-6632 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T43 6729-6733 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T44 6852-6869 Body_part denotes protein complexes http://purl.org/sig/ont/fma/fma67906
T45 6852-6859 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T46 6936-6944 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T47 7042-7049 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T48 7213-7221 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T49 7252-7256 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T50 7257-7272 Body_part denotes plasma-membrane http://purl.org/sig/ont/fma/fma63841
T51 7309-7322 Body_part denotes glycoproteins http://purl.org/sig/ont/fma/fma62925
T52 7398-7405 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T53 7466-7474 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T54 7770-7782 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T55 7954-7958 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T56 8026-8030 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T57 8065-8082 Body_part denotes cellular membrane http://purl.org/sig/ont/fma/fma63841
T58 8113-8117 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T59 8490-8500 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T60 8567-8574 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T61 8645-8652 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T62 8850-8863 Body_part denotes cell membrane http://purl.org/sig/ont/fma/fma63841
T63 8850-8854 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T64 9046-9050 Body_part denotes neck http://purl.org/sig/ont/fma/fma7155
T65 9104-9109 Body_part denotes helix http://purl.org/sig/ont/fma/fma60992
T66 9214-9225 Body_part denotes amino acids http://purl.org/sig/ont/fma/fma82739
T67 9265-9269 Body_part denotes neck http://purl.org/sig/ont/fma/fma7155
T68 9534-9546 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T69 9534-9538 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T70 9607-9612 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T71 9698-9702 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T72 9746-9755 Body_part denotes endosomal http://purl.org/sig/ont/fma/fma67180
T73 9826-9833 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T74 10107-10114 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T75 10245-10253 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T76 10319-10327 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T77 10699-10704 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T78 10854-10860 Body_part denotes sputum http://purl.org/sig/ont/fma/fma312401
T79 10949-10955 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T80 10962-10965 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T81 11027-11038 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T82 11056-11059 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T83 11092-11095 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T84 11101-11107 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T85 11123-11126 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T86 11224-11230 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T87 11478-11484 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T88 11485-11488 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T89 11818-11822 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T90 12207-12215 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T91 12277-12284 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T92 12357-12365 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T93 12666-12672 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T94 13850-13854 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T95 13906-13910 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T96 14417-14439 Body_part denotes gastrointestinal tract http://purl.org/sig/ont/fma/fma71132
T97 14482-14486 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T98 14504-14510 Body_part denotes Tissue http://purl.org/sig/ont/fma/fma9637
T99 14511-14516 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T100 14870-14875 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T101 14979-14985 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T102 15240-15245 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T103 15350-15359 Body_part denotes connexins http://purl.org/sig/ont/fma/fma67882
T104 15372-15384 Body_part denotes gap junction http://purl.org/sig/ont/fma/fma67423
T105 15615-15630 Body_part denotes coronary artery http://purl.org/sig/ont/fma/fma49893
T106 15782-15792 Body_part denotes myocardium http://purl.org/sig/ont/fma/fma9462
T107 15932-15937 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T108 16011-16019 Body_part denotes platelet http://purl.org/sig/ont/fma/fma62851
T109 16344-16352 Body_part denotes platelet http://purl.org/sig/ont/fma/fma62851
T110 16902-16910 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T111 17140-17151 Body_part denotes hepatocytes http://purl.org/sig/ont/fma/fma14515
T112 17156-17173 Body_part denotes endothelial cells http://purl.org/sig/ont/fma/fma66772
T113 17168-17173 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T114 17221-17228 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T115 17261-17279 Body_part denotes hepatic parenchyma http://purl.org/sig/ont/fma/fma17540
T116 17301-17312 Body_part denotes hepatocytes http://purl.org/sig/ont/fma/fma14515
T117 17361-17368 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T118 17394-17398 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T119 17400-17407 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T120 17466-17470 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T121 17525-17530 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T122 17537-17548 Body_part denotes CD34+ cells http://purl.org/sig/ont/fma/fma0326120
T123 17543-17548 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T124 17723-17739 Body_part denotes pulmonary artery http://purl.org/sig/ont/fma/fma66326
T125 17740-17759 Body_part denotes smooth muscle cells http://purl.org/sig/ont/fma/fma14072
T126 17754-17759 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T127 17808-17812 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T128 17817-17824 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T129 18007-18018 Body_part denotes endothelium http://purl.org/sig/ont/fma/fma63916
T130 18030-18036 Body_part denotes muscle http://purl.org/sig/ont/fma/fma32558
T131 18046-18060 Body_part denotes left ventricle http://purl.org/sig/ont/fma/fma7101
T132 18106-18111 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T133 18461-18465 Body_part denotes axis http://purl.org/sig/ont/fma/fma12520
T134 18509-18513 Body_part denotes axis http://purl.org/sig/ont/fma/fma12520
T135 18517-18522 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T136 18619-18623 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T137 19028-19034 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T138 19068-19074 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T139 19208-19213 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T140 19571-19575 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T141 20224-20229 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T142 20302-20308 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T143 20339-20344 Body_part denotes bowel http://purl.org/sig/ont/fma/fma7199
T144 20570-20574 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T145 20575-20585 Body_part denotes fibroblast http://purl.org/sig/ont/fma/fma63877
T146 20693-20697 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T147 20711-20731 Body_part denotes extracellular matrix http://purl.org/sig/ont/fma/fma9672
T148 20762-20770 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T149 20829-20833 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T150 21054-21058 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T151 21157-21170 Body_part denotes cell membrane http://purl.org/sig/ont/fma/fma63841
T152 21157-21161 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T153 21479-21483 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T154 21582-21594 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T155 21582-21586 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T156 21677-21681 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T157 21819-21823 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T158 21824-21831 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T159 22027-22031 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T160 22196-22206 Body_part denotes eosinophil http://purl.org/sig/ont/fma/fma62861
T161 22220-22225 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T162 22240-22248 Body_part denotes alveolar http://purl.org/sig/ont/fma/fma264783
T163 22300-22304 Body_part denotes axis http://purl.org/sig/ont/fma/fma12520
T164 22347-22357 Body_part denotes eosinophil http://purl.org/sig/ont/fma/fma62861
T165 22358-22362 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T166 22804-22810 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T167 22950-22955 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T168 23075-23087 Body_part denotes compartments http://purl.org/sig/ont/fma/fma76577
T169 23201-23211 Body_part denotes eosinophil http://purl.org/sig/ont/fma/fma62861
T170 23484-23493 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T171 23661-23665 Body_part denotes axis http://purl.org/sig/ont/fma/fma12520
T172 23906-23910 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T173 24039-24043 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T174 24377-24381 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T175 24396-24410 Body_part denotes left ventricle http://purl.org/sig/ont/fma/fma7101
T176 24553-24569 Body_part denotes cardiac myocytes http://purl.org/sig/ont/fma/fma14067
T177 24633-24637 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T178 24818-24834 Body_part denotes cardiac myocytes http://purl.org/sig/ont/fma/fma14067
T179 24850-24878 Body_part denotes vascular smooth muscle cells http://purl.org/sig/ont/fma/fma284560
T180 24873-24878 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T181 24938-24942 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T182 25433-25440 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T183 26468-26481 Body_part denotes cell membrane http://purl.org/sig/ont/fma/fma63841
T184 26468-26472 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T185 26923-26930 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T186 27534-27546 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T187 27707-27711 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T188 27831-27836 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T189 27897-27913 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T190 27908-27913 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T191 27940-27949 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T192 27967-27971 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T193 28093-28097 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T194 28172-28181 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T195 28200-28204 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T196 28598-28609 Body_part denotes cytoplasmic http://purl.org/sig/ont/fma/fma66835
T197 28859-28866 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T198 29005-29009 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T199 29155-29159 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T200 29209-29213 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T201 30041-30045 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T202 30095-30099 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T203 30108-30121 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T204 30660-30664 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T205 31240-31245 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T206 31455-31460 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T207 31488-31492 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T208 31674-31679 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T209 31694-31698 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T210 31729-31743 Body_part denotes cell membranes http://purl.org/sig/ont/fma/fma63841
T211 31729-31733 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T212 31805-31809 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T213 33171-33177 Body_part denotes serine http://purl.org/sig/ont/fma/fma82764
T214 34023-34027 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T215 34880-34885 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T216 35277-35296 Body_part denotes smooth muscle cells http://purl.org/sig/ont/fma/fma14072
T217 35291-35296 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T218 35542-35547 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T219 35974-35979 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T220 36001-36008 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T221 36136-36147 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T222 36154-36159 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T223 36408-36413 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T224 36430-36435 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T225 36885-36896 Body_part denotes vasculature http://purl.org/sig/ont/fma/fma69050
T226 37336-37346 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T227 37522-37529 Body_part denotes proline http://purl.org/sig/ont/fma/fma82761
T228 37797-37802 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T229 37804-37811 Body_part denotes kidneys http://purl.org/sig/ont/fma/fma7203
T230 37813-37818 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T231 37820-37825 Body_part denotes colon http://purl.org/sig/ont/fma/fma14543
T232 37827-37842 Body_part denotes small intestine http://purl.org/sig/ont/fma/fma7200
T233 37844-37848 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T234 37850-37855 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T235 37901-37908 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T236 37935-37949 Body_part denotes cardiomyocytes http://purl.org/sig/ont/fma/fma14067
T237 37951-37962 Body_part denotes endothelium http://purl.org/sig/ont/fma/fma63916
T238 37964-37986 Body_part denotes alveolar type II cells http://purl.org/sig/ont/fma/fma62501
T239 37981-37986 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T240 38004-38009 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T241 38011-38039 Body_part denotes vascular smooth muscle cells http://purl.org/sig/ont/fma/fma284560
T242 38034-38039 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T243 38055-38067 Body_part denotes Leydig cells http://purl.org/sig/ont/fma/fma72297
T244 38062-38067 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T245 38131-38158 Body_part denotes surface of epithelial cells http://purl.org/sig/ont/fma/fma82998
T246 38153-38158 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T247 38162-38175 Body_part denotes renal tubules http://purl.org/sig/ont/fma/fma15627
T248 38177-38181 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T249 38229-38234 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T250 38300-38304 Body_part denotes axis http://purl.org/sig/ont/fma/fma12520
T251 39052-39058 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T252 39242-39248 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T253 39467-39473 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T254 39493-39500 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T255 39715-39720 Body_part denotes bowel http://purl.org/sig/ont/fma/fma7199
T256 39809-39815 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T257 39863-39869 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T258 40054-40060 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T259 40093-40099 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T260 40146-40152 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T261 40370-40376 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T262 40682-40688 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T263 40930-40935 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T264 41141-41146 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T265 41243-41249 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T266 41333-41338 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T267 41597-41603 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T268 41648-41653 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T269 41833-41839 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T270 41958-41964 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T271 42689-42695 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T272 42964-42970 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T273 43637-43643 Body_part denotes muscle http://purl.org/sig/ont/fma/fma32558
T274 43693-43702 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T275 43713-43717 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T276 43761-43770 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T277 43961-43970 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T278 44110-44118 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T279 44132-44141 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T280 44162-44166 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T281 44354-44359 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T282 44360-44365 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T283 44459-44468 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T284 44480-44484 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T285 44531-44539 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T286 44567-44585 Body_part denotes pulmonary arterial http://purl.org/sig/ont/fma/fma66326
T287 44671-44675 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T288 44678-44682 Body_part denotes IL-2 http://purl.org/sig/ont/fma/fma84051
T289 44709-44714 Body_part denotes IL-12 http://purl.org/sig/ont/fma/fma86579
T290 44947-44955 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T291 45374-45396 Body_part denotes gastrointestinal tract http://purl.org/sig/ont/fma/fma71132
T292 45402-45413 Body_part denotes enterocytes http://purl.org/sig/ont/fma/fma62122
T293 45460-45467 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T294 45816-45826 Body_part denotes intestinal http://purl.org/sig/ont/fma/fma7199
T295 46094-46098 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T296 46142-46153 Body_part denotes amino acids http://purl.org/sig/ont/fma/fma82739
T297 46155-46157 Body_part denotes AA http://purl.org/sig/ont/fma/fma82739
T298 46199-46207 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T299 46398-46400 Body_part denotes AA http://purl.org/sig/ont/fma/fma82739
T300 46428-46439 Body_part denotes enterocytes http://purl.org/sig/ont/fma/fma62122
T301 46490-46500 Body_part denotes enterocyte http://purl.org/sig/ont/fma/fma62122
T302 46530-46540 Body_part denotes intestinal http://purl.org/sig/ont/fma/fma7199
T303 46573-46578 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T304 46643-46645 Body_part denotes AA http://purl.org/sig/ont/fma/fma82739
T305 46744-46746 Body_part denotes AA http://purl.org/sig/ont/fma/fma82739
T306 46760-46762 Body_part denotes AA http://purl.org/sig/ont/fma/fma82739
T307 46785-46796 Body_part denotes enterocytes http://purl.org/sig/ont/fma/fma62122
T308 46825-46827 Body_part denotes AA http://purl.org/sig/ont/fma/fma82739
T309 46897-46899 Body_part denotes AA http://purl.org/sig/ont/fma/fma82739
T310 46952-46959 Body_part denotes insulin http://purl.org/sig/ont/fma/fma83365
T311 46999-47004 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T312 47164-47170 Body_part denotes Plasma http://purl.org/sig/ont/fma/fma62970
T313 47236-47246 Body_part denotes intestinal http://purl.org/sig/ont/fma/fma7199
T314 47406-47411 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T315 47421-47426 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T316 47490-47497 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T317 47501-47507 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T318 47522-47526 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T319 47581-47583 Body_part denotes AA http://purl.org/sig/ont/fma/fma82739
T320 47730-47742 Body_part denotes blood plasma http://purl.org/sig/ont/fma/fma62970
T321 47810-47827 Body_part denotes endothelial cells http://purl.org/sig/ont/fma/fma66772
T322 47822-47827 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T323 47859-47876 Body_part denotes endothelial cells http://purl.org/sig/ont/fma/fma66772
T324 47871-47876 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T325 47929-47935 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T326 47939-47946 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T327 48112-48116 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T328 48133-48139 Body_part denotes Plasma http://purl.org/sig/ont/fma/fma62970
T329 48198-48210 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T330 48198-48202 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T331 48219-48224 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T332 48241-48247 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T333 48266-48271 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T334 48273-48290 Body_part denotes endothelial cells http://purl.org/sig/ont/fma/fma66772
T335 48285-48290 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T336 48292-48299 Body_part denotes neurons http://purl.org/sig/ont/fma/fma54527
T337 48304-48318 Body_part denotes cardiomyocytes http://purl.org/sig/ont/fma/fma14067
T338 48582-48597 Body_part denotes plasma to cells http://purl.org/sig/ont/fma/fma70574
T339 48582-48588 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T340 48592-48597 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T341 48686-48691 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T342 49415-49419 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T343 49431-49437 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T344 49683-49694 Body_part denotes neural cell http://purl.org/sig/ont/fma/fma70333
T345 49690-49694 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T346 49769-49775 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T347 49804-49811 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T348 49884-49894 Body_part denotes fatty acid http://purl.org/sig/ont/fma/fma82738
T349 49896-49899 Body_part denotes FFA http://purl.org/sig/ont/fma/fma82738
T350 50196-50199 Body_part denotes FFA http://purl.org/sig/ont/fma/fma82738
T351 50432-50438 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T352 50621-50627 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T353 50891-50898 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T354 51099-51105 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T355 51169-51175 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T356 51279-51283 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T357 51311-51317 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T358 51380-51386 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T359 51770-51775 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T360 51989-51995 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T361 52061-52066 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T362 52244-52260 Body_part denotes endothelial cell http://purl.org/sig/ont/fma/fma66772
T363 52256-52260 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T364 52316-52334 Body_part denotes pulmonary arteries http://purl.org/sig/ont/fma/fma66326
T365 52326-52334 Body_part denotes arteries http://purl.org/sig/ont/fma/fma63812
T366 52438-52446 Body_part denotes alveolar http://purl.org/sig/ont/fma/fma264783
T367 52592-52596 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T368 52647-52651 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T369 53894-53906 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T370 53894-53898 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T371 53949-53956 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T372 54023-54030 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T373 54089-54104 Body_part denotes plasma membrane http://purl.org/sig/ont/fma/fma63841
T374 54291-54299 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T375 54376-54380 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T376 54388-54395 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T377 54573-54581 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T378 54819-54827 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T379 56000-56005 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T380 57294-57300 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T381 57822-57827 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T382 57962-57967 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T383 58321-58326 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T384 58447-58459 Body_part denotes baroreceptor http://purl.org/sig/ont/fma/fma85601
T385 59201-59205 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T386 60337-60342 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T387 60344-60348 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T388 60350-60355 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T389 60357-60362 Body_part denotes colon http://purl.org/sig/ont/fma/fma14543
T390 60372-60379 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T391 60411-60416 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T392 60421-60438 Body_part denotes endothelial cells http://purl.org/sig/ont/fma/fma66772
T393 60433-60438 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T394 61159-61165 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T395 61301-61307 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T396 61377-61383 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T397 62341-62346 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T398 62645-62649 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T399 62651-62656 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T400 62783-62789 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T401 63106-63111 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T402 63199-63214 Body_part denotes plasma membrane http://purl.org/sig/ont/fma/fma63841
T403 63634-63643 Body_part denotes lysosomes http://purl.org/sig/ont/fma/fma63836
T404 63945-63953 Body_part denotes platelet http://purl.org/sig/ont/fma/fma62851
T405 63993-64001 Body_part denotes platelet http://purl.org/sig/ont/fma/fma62851
T406 64050-64068 Body_part denotes secretory granules http://purl.org/sig/ont/fma/fma84758
T407 64132-64140 Body_part denotes platelet http://purl.org/sig/ont/fma/fma62851
T408 65145-65157 Body_part denotes renal artery http://purl.org/sig/ont/fma/fma14751
T409 65422-65432 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T410 65697-65703 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T411 65841-65848 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T412 65852-65858 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T413 65902-65904 Body_part denotes AA http://purl.org/sig/ont/fma/fma82739
T414 66004-66006 Body_part denotes AA http://purl.org/sig/ont/fma/fma82739
T415 66057-66068 Body_part denotes amino acids http://purl.org/sig/ont/fma/fma82739
T416 66120-66122 Body_part denotes AA http://purl.org/sig/ont/fma/fma82739
T417 66507-66517 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T418 66682-66690 Body_part denotes arginine http://purl.org/sig/ont/fma/fma82763
T419 66921-66928 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T420 67608-67614 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T421 67967-67977 Body_part denotes intestinal http://purl.org/sig/ont/fma/fma7199
T422 68556-68564 Body_part denotes cavities http://purl.org/sig/ont/fma/fma76576
T423 69624-69631 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T424 70594-70600 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T425 71691-71705 Body_part denotes left ventricle http://purl.org/sig/ont/fma/fma7101
T426 71740-71746 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T427 72311-72318 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T428 72339-72355 Body_part denotes pulmonary artery http://purl.org/sig/ont/fma/fma66326
T429 72356-72375 Body_part denotes smooth muscle cells http://purl.org/sig/ont/fma/fma14072
T430 72370-72375 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T431 74191-74195 Body_part denotes face http://purl.org/sig/ont/fma/fma24728
T432 74632-74639 Body_part denotes insulin http://purl.org/sig/ont/fma/fma83365
T433 74776-74780 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T434 74797-74804 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T435 74832-74838 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T436 74846-74851 Body_part denotes urine http://purl.org/sig/ont/fma/fma12274
T437 75209-75215 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T438 75225-75229 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T439 75240-75245 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T440 75268-75272 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T441 75357-75362 Body_part denotes bowel http://purl.org/sig/ont/fma/fma7199
T442 75478-75483 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T443 75575-75581 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T444 76154-76161 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T445 76742-76748 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T446 76986-76991 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T447 77008-77015 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T448 77034-77040 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T449 77283-77288 Body_part denotes urine http://purl.org/sig/ont/fma/fma12274
T450 77327-77334 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T451 77615-77620 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T452 77966-77971 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T453 77986-77990 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T454 77991-77998 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T455 78120-78124 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T456 78306-78314 Body_part denotes intronic http://purl.org/sig/ont/fma/fma84121
T457 78512-78516 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T458 78537-78541 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T459 80075-80080 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T460 81563-81569 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T461 81899-81902 Body_part denotes V-2 http://purl.org/sig/ont/fma/fma13443|http://purl.org/sig/ont/fma/fma68615
T463 82209-82213 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T464 82214-82226 Body_part denotes eosinophilic http://purl.org/sig/ont/fma/fma62861
T465 82311-82321 Body_part denotes eosinophil http://purl.org/sig/ont/fma/fma62861
T466 82563-82567 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T467 82624-82632 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T468 82662-82667 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T469 82668-82677 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T470 82747-82756 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T471 82799-82804 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T472 82877-82885 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T473 83451-83459 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T474 83691-83696 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T475 83877-83882 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T476 83958-83966 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T477 84243-84248 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T478 84312-84317 Body_part denotes Organ http://purl.org/sig/ont/fma/fma67498
T479 84679-84687 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T480 84789-84794 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T481 84965-84971 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T482 85052-85058 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T483 85470-85475 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T484 85621-85637 Body_part denotes surface of cells http://purl.org/sig/ont/fma/fma67653
T485 85632-85637 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T486 85887-85893 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T487 86018-86024 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T488 86096-86102 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T489 86469-86475 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T490 86698-86702 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T491 86983-86989 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T492 87060-87078 Body_part denotes pulmonary arterial http://purl.org/sig/ont/fma/fma66326
T493 87290-87294 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T494 87706-87710 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T495 88291-88297 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T496 88799-88805 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T497 89125-89130 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T498 89202-89208 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T499 89343-89349 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T500 91853-91859 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T501 92265-92271 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T502 92458-92464 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T503 93228-93234 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T504 93600-93606 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T505 94323-94329 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T506 94362-94368 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T507 94429-94444 Body_part denotes coronary artery http://purl.org/sig/ont/fma/fma49893
T508 94622-94627 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T509 94826-94832 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T510 95366-95370 Body_part denotes axis http://purl.org/sig/ont/fma/fma12520
T511 96260-96264 Body_part denotes face http://purl.org/sig/ont/fma/fma24728
T512 97461-97466 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T513 97610-97618 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T514 98545-98552 Body_part denotes insulin http://purl.org/sig/ont/fma/fma83365

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T6 2810-2816 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T7 3264-3268 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T8 3459-3463 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T9 3656-3665 Body_part denotes epithelia http://purl.obolibrary.org/obo/UBERON_0000483
T10 4260-4269 Body_part denotes epithelia http://purl.obolibrary.org/obo/UBERON_0000483
T11 6320-6340 Body_part denotes bronchial epithelium http://purl.obolibrary.org/obo/UBERON_0002031
T12 6330-6340 Body_part denotes epithelium http://purl.obolibrary.org/obo/UBERON_0000483
T13 6729-6733 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T14 7954-7958 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T15 8026-8030 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T16 9046-9050 Body_part denotes neck http://purl.obolibrary.org/obo/UBERON_0000974
T17 9104-9109 Body_part denotes helix http://purl.obolibrary.org/obo/UBERON_0002488
T18 9265-9269 Body_part denotes neck http://purl.obolibrary.org/obo/UBERON_0000974
T19 10684-10690 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T20 10854-10860 Body_part denotes sputum http://purl.obolibrary.org/obo/UBERON_0007311
T21 11818-11822 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T22 12933-12957 Body_part denotes renin-angiotensin system http://purl.obolibrary.org/obo/UBERON_0018229
T23 12959-12962 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T24 13906-13910 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T25 14482-14486 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T26 14504-14510 Body_part denotes Tissue http://purl.obolibrary.org/obo/UBERON_0000479
T27 14511-14516 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T28 14870-14875 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T29 15240-15245 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T30 15615-15630 Body_part denotes coronary artery http://purl.obolibrary.org/obo/UBERON_0001621
T31 15624-15630 Body_part denotes artery http://purl.obolibrary.org/obo/UBERON_0001637
T32 15782-15792 Body_part denotes myocardium http://purl.obolibrary.org/obo/UBERON_0002349
T33 15932-15937 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T34 17269-17279 Body_part denotes parenchyma http://purl.obolibrary.org/obo/UBERON_0000353
T35 17525-17530 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T36 17723-17739 Body_part denotes pulmonary artery http://purl.obolibrary.org/obo/UBERON_0002012
T37 17733-17739 Body_part denotes artery http://purl.obolibrary.org/obo/UBERON_0001637
T38 17790-17793 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T39 18007-18018 Body_part denotes endothelium http://purl.obolibrary.org/obo/UBERON_0001986
T40 18106-18111 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T41 18171-18174 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T42 18346-18349 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T43 19571-19575 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T44 19788-19791 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T45 20224-20229 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T46 20570-20574 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T47 20693-20697 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T48 20829-20833 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T49 21054-21058 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T50 21479-21483 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T51 21677-21681 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T52 21819-21823 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T53 22027-22031 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T54 23835-23838 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T55 25600-25603 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T56 26185-26188 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T57 26668-26671 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T58 28610-28614 Body_part denotes tail http://purl.obolibrary.org/obo/UBERON_0002415
T59 29155-29159 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T60 29209-29213 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T61 29405-29429 Body_part denotes renin–angiotensin system http://purl.obolibrary.org/obo/UBERON_0018229
T62 30041-30045 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T63 30095-30099 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T64 30108-30121 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T65 30660-30664 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T66 30766-30769 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T67 31124-31127 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T68 31240-31245 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T69 31488-31492 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T70 31694-31698 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T71 31805-31809 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T72 32039-32045 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T73 32534-32537 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T74 32783-32786 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T75 32924-32927 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T76 33730-33733 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T77 34210-34213 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T78 34243-34246 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T79 35542-35547 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T80 35974-35979 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T81 36408-36413 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T82 36430-36435 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T83 36885-36896 Body_part denotes vasculature http://purl.obolibrary.org/obo/UBERON_0002049
T84 37075-37078 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T85 37612-37615 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T86 37797-37802 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T87 37813-37818 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T88 37820-37825 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155
T89 37827-37842 Body_part denotes small intestine http://purl.obolibrary.org/obo/UBERON_0002108
T90 37833-37842 Body_part denotes intestine http://purl.obolibrary.org/obo/UBERON_0000160
T91 37844-37848 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T92 37850-37855 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T93 37951-37962 Body_part denotes endothelium http://purl.obolibrary.org/obo/UBERON_0001986
T94 38162-38175 Body_part denotes renal tubules http://purl.obolibrary.org/obo/UBERON_0009773
T95 38177-38181 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T96 40930-40935 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T97 41141-41146 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T98 41648-41653 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T99 41860-41863 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T100 41958-41964 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T101 43242-43245 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T102 44354-44359 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T103 44567-44585 Body_part denotes pulmonary arterial http://purl.obolibrary.org/obo/UBERON_0002012
T104 46094-46098 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T105 46573-46578 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T106 47406-47411 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T107 47421-47426 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T108 47522-47526 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T109 47730-47742 Body_part denotes blood plasma http://purl.obolibrary.org/obo/UBERON_0001969
T110 47730-47735 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T111 48686-48691 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T112 49415-49419 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T113 51260-51263 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T114 51279-51283 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T115 51770-51775 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T116 52061-52066 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T117 52316-52334 Body_part denotes pulmonary arteries http://purl.obolibrary.org/obo/UBERON_0002012
T118 52592-52596 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T119 52647-52651 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T120 53377-53382 Body_part denotes shell http://purl.obolibrary.org/obo/UBERON_0006612
T121 54376-54380 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T122 57822-57827 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T123 57962-57967 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T124 58321-58326 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T125 58447-58459 Body_part denotes baroreceptor http://purl.obolibrary.org/obo/UBERON_0004019
T126 59201-59205 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T127 60337-60342 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T128 60344-60348 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T129 60350-60355 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T130 60357-60362 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155
T131 60380-60386 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T132 60411-60416 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T133 62341-62346 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T134 64574-64577 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T135 65145-65157 Body_part denotes renal artery http://purl.obolibrary.org/obo/UBERON_0001184
T136 65151-65157 Body_part denotes artery http://purl.obolibrary.org/obo/UBERON_0001637
T137 65508-65511 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T138 65587-65590 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T139 72339-72355 Body_part denotes pulmonary artery http://purl.obolibrary.org/obo/UBERON_0002012
T140 72349-72355 Body_part denotes artery http://purl.obolibrary.org/obo/UBERON_0001637
T141 74191-74195 Body_part denotes face http://purl.obolibrary.org/obo/UBERON_0001456
T142 74776-74780 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T143 74846-74851 Body_part denotes urine http://purl.obolibrary.org/obo/UBERON_0001088
T144 75268-75272 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T145 75478-75483 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T146 76742-76748 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T147 76986-76991 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T148 77034-77040 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T149 77283-77288 Body_part denotes urine http://purl.obolibrary.org/obo/UBERON_0001088
T150 77615-77620 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T151 77720-77723 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T152 77966-77971 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T153 78537-78541 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T154 79239-79242 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T155 79976-79979 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T156 80020-80023 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T157 80075-80080 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T158 81419-81422 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T159 82209-82213 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T160 82563-82567 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T161 82662-82667 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T162 83804-83807 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T163 83877-83882 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T164 84243-84248 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T165 84312-84317 Body_part denotes Organ http://purl.obolibrary.org/obo/UBERON_0000062
T166 84789-84794 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T167 84946-84949 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T168 85470-85475 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T169 85645-85651 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T170 86698-86702 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T171 86967-86970 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T172 87060-87078 Body_part denotes pulmonary arterial http://purl.obolibrary.org/obo/UBERON_0002012
T173 87197-87200 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T174 87290-87294 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T175 87626-87629 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T176 87706-87710 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T177 88828-88831 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T178 89054-89057 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T179 89125-89130 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T180 89146-89149 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T181 89458-89461 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T182 89567-89570 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T183 90522-90525 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T184 91085-91088 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T185 91579-91582 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T186 93120-93123 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T187 93203-93206 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T188 93517-93520 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T189 94429-94444 Body_part denotes coronary artery http://purl.obolibrary.org/obo/UBERON_0001621
T190 94438-94444 Body_part denotes artery http://purl.obolibrary.org/obo/UBERON_0001637
T191 94622-94627 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T192 94849-94852 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T193 96260-96264 Body_part denotes face http://purl.obolibrary.org/obo/UBERON_0001456
T194 96885-96888 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T195 99139-99154 Body_part denotes digestive tract http://purl.obolibrary.org/obo/UBERON_0001555
T196 99644-99649 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T197 100077-100081 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T198 100238-100242 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T199 100310-100327 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T200 100840-100843 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T201 101333-101337 Body_part denotes face http://purl.obolibrary.org/obo/UBERON_0001456
T202 101371-101375 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T203 101755-101760 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T204 101761-101765 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T205 101766-101771 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T206 101772-101781 Body_part denotes intestine http://purl.obolibrary.org/obo/UBERON_0000160
T207 101782-101788 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T208 101789-101802 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T209 101803-101808 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T210 101950-101955 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T211 102197-102201 Body_part denotes face http://purl.obolibrary.org/obo/UBERON_0001456
T212 102423-102426 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T213 102769-102773 Body_part denotes face http://purl.obolibrary.org/obo/UBERON_0001456
T214 102941-102944 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T215 103536-103539 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T216 104132-104135 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T217 104491-104494 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T218 104792-104807 Body_part denotes coronary artery http://purl.obolibrary.org/obo/UBERON_0001621
T219 104801-104807 Body_part denotes artery http://purl.obolibrary.org/obo/UBERON_0001637
T220 104870-104873 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T221 105029-105034 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T222 106849-106854 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T223 107222-107226 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T224 107227-107233 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T225 108352-108356 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T226 109938-109943 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T227 110005-110008 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T228 110723-110726 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T229 111200-111203 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
88 1109-1114 Gene denotes IL-1β Gene:3552
89 1116-1120 Gene denotes IL-6 Gene:3569
90 1122-1126 Gene denotes IL-8 Gene:3576
91 1128-1133 Gene denotes IL-10 Gene:3586
92 1138-1142 Gene denotes TNFα Gene:7124
93 26-73 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
94 75-85 Species denotes SARS-CoV-2 Tax:2697049
95 275-283 Species denotes patients Tax:9606
96 694-702 Species denotes patients Tax:9606
97 726-734 Species denotes patients Tax:9606
98 1409-1417 Species denotes patients Tax:9606
99 1467-1475 Species denotes patients Tax:9606
100 1832-1839 Species denotes patient Tax:9606
101 1872-1880 Species denotes patients Tax:9606
102 2328-2336 Species denotes patients Tax:9606
103 2621-2629 Species denotes patients Tax:9606
104 2825-2833 Species denotes patients Tax:9606
105 2881-2889 Species denotes patients Tax:9606
106 2338-2341 Gene denotes Th2 Gene:15111
107 322-328 Chemical denotes oxygen MESH:D010100
108 380-391 Chemical denotes chloroquine MESH:D002738
109 397-407 Chemical denotes macrolides MESH:D018942
110 87-96 Disease denotes infection MESH:D007239
111 117-125 Disease denotes COVID-19 MESH:C000657245
112 255-263 Disease denotes COVID-19 MESH:C000657245
113 264-273 Disease denotes infection MESH:D007239
114 441-461 Disease denotes SARS-CoV-2 infection MESH:C000657245
115 564-590 Disease denotes acute respiratory syndrome MESH:D012120
116 613-618 Disease denotes death MESH:D003643
117 743-772 Disease denotes lymphopaenia and eosinopaenia
118 850-862 Disease denotes eosinopaenia
119 963-989 Disease denotes cardiac dysfunction/injury MESH:D006331
120 991-1019 Disease denotes respiratory distress/illness MESH:D012140
121 1021-1061 Disease denotes coagulopathy, hypoproteinaemia, acidosis MESH:D000138
122 1063-1070 Disease denotes hypoxia MESH:D000860
123 1178-1190 Disease denotes hypertension MESH:D006973
124 1271-1285 Disease denotes severe disease MESH:D045169
125 1349-1355 Disease denotes asthma MESH:D001249
126 1400-1408 Disease denotes infected MESH:D007239
127 1458-1466 Disease denotes allergic MESH:D004342
128 1570-1576 Disease denotes asthma MESH:D001249
129 1638-1654 Disease denotes Viral infections MESH:D001102
130 1684-1700 Disease denotes allergic disease MESH:D004342
131 2011-2031 Disease denotes hypertensive disease MESH:D006973
132 2122-2137 Disease denotes virus infection MESH:D001102
133 2182-2194 Disease denotes hypertension MESH:D006973
134 2319-2327 Disease denotes infected MESH:D007239
135 2351-2368 Disease denotes allergic diseases MESH:D004342
136 2525-2537 Disease denotes hypertensive MESH:D006973
137 2599-2607 Disease denotes COVID-19 MESH:C000657245
138 2645-2666 Disease denotes chronic renal disease MESH:D051436
139 2802-2824 Disease denotes chronic kidney disease MESH:D051436
140 2858-2866 Disease denotes COVID-19 MESH:C000657245
141 2874-2880 Disease denotes asthma MESH:D001249
145 2895-2899 Gene denotes ACE2 Gene:59272
146 2909-2917 Species denotes SARS-CoV Tax:694009
147 2922-2943 Disease denotes SARS-CoV-2 Infections MESH:C000657245
226 2944-2975 Gene denotes Angiotensin-converting enzyme 2 Gene:59272
227 2977-2981 Gene denotes ACE2 Gene:59272
228 3108-3112 Gene denotes ACE2 Gene:59272
229 3365-3369 Gene denotes ACE2 Gene:70008
230 3503-3507 Gene denotes ACE2 Gene:70008
231 3565-3569 Gene denotes ACE2 Gene:59272
232 3793-3797 Gene denotes ACE2 Gene:59272
233 3847-3853 Gene denotes ADAM17 Gene:6868
234 3927-3931 Gene denotes TNFα Gene:7124
235 3956-3960 Gene denotes ACE2 Gene:59272
236 4042-4047 Gene denotes IL-1β Gene:3552
237 4052-4056 Gene denotes TNFα Gene:7124
238 4194-4198 Gene denotes ACE2 Gene:59272
239 4488-4492 Gene denotes ACE2 Gene:59272
240 4556-4560 Gene denotes ACE2 Gene:59272
241 4637-4643 Gene denotes ADAM17 Gene:6868
242 4644-4648 Gene denotes TACE Gene:6868
243 4658-4662 Gene denotes ACE2 Gene:59272
244 4675-4679 Gene denotes ACE2 Gene:59272
245 4860-4864 Gene denotes ACE2 Gene:59272
246 4900-4904 Gene denotes ACE2 Gene:59272
247 4974-4978 Gene denotes ACE2 Gene:59272
248 5137-5141 Gene denotes ACE2 Gene:59272
249 5431-5436 Gene denotes renin Gene:5972
250 5441-5454 Gene denotes angiotensin I Gene:183
251 5473-5476 Gene denotes ACE Gene:59272
252 5477-5481 Gene denotes ACE2 Gene:59272
253 5588-5592 Gene denotes ACE2 Gene:59272
254 5815-5819 Gene denotes ACE2 Gene:59272
255 6017-6021 Gene denotes ACE2 Gene:59272
256 6182-6186 Gene denotes ACE2 Gene:59272
257 6295-6299 Gene denotes ACE2 Gene:59272
258 6549-6553 Gene denotes ACE2 Gene:59272
259 6564-6568 Gene denotes ACE2 Gene:59272
260 6674-6678 Gene denotes ACE2 Gene:59272
261 6759-6763 Gene denotes ACE2 Gene:59272
262 3741-3746 Gene denotes spike Gene:43740568
263 3317-3322 Gene denotes spike Gene:43740568
264 3020-3025 Gene denotes spike Gene:43740568
265 3041-3049 Species denotes SARS-CoV Tax:694009
266 3287-3295 Species denotes SARS-CoV Tax:694009
267 3473-3477 Species denotes mice Tax:10090
268 3643-3648 Species denotes human Tax:9606
269 4159-4167 Species denotes patients Tax:9606
270 4247-4252 Species denotes human Tax:9606
271 4515-4523 Species denotes SARS-CoV Tax:694009
272 4830-4833 Species denotes CoV Tax:11118
273 5514-5522 Species denotes SARS-CoV Tax:694009
274 5523-5531 Species denotes patients Tax:9606
275 6025-6030 Species denotes human Tax:9606
276 6061-6069 Species denotes SARS-CoV Tax:694009
277 6489-6497 Species denotes patients Tax:9606
278 6530-6540 Species denotes SARS-CoV-2 Tax:2697049
279 6636-6646 Species denotes SARS-CoV-2 Tax:2697049
280 6702-6712 Species denotes SARS-CoV-2 Tax:2697049
281 6794-6802 Species denotes SARS-CoV Tax:694009
282 6619-6624 Gene denotes spike Gene:43740568
283 5638-5643 Gene denotes spike Gene:43740568
284 5544-5549 Gene denotes spike Gene:43740568
285 4877-4882 Gene denotes spike Gene:43740568
286 4498-4503 Gene denotes spike Gene:43740568
287 4396-4401 Gene denotes spike Gene:43740568
288 4358-4363 Gene denotes spike Gene:43740568
289 4007-4012 Gene denotes spike Gene:43740568
290 3345-3347 Chemical denotes 3h MESH:D014316
291 3264-3275 Disease denotes lung injury MESH:D055370
292 3545-3554 Disease denotes infection MESH:D007239
293 4150-4158 Disease denotes COVID-19 MESH:C000657245
294 4757-4772 Disease denotes viral infection MESH:D001102
295 5072-5090 Disease denotes SARS-CoV infection MESH:C000657245
296 5220-5235 Disease denotes viral infection MESH:D001102
297 5357-5385 Disease denotes cardiovascular complications MESH:D002318
298 5396-5407 Disease denotes hypotension MESH:D007022
299 5487-5498 Disease denotes tachycardia MESH:D013610
300 6047-6055 Disease denotes infected MESH:D007239
301 6106-6115 Disease denotes infection MESH:D007239
302 6236-6245 Disease denotes infection MESH:D007239
303 6729-6740 Disease denotes lung injury MESH:D055370
307 6847-6851 Gene denotes ACE2 Gene:59272
308 6883-6887 Gene denotes ACE2 Gene:59272
309 6841-6846 Gene denotes spike Gene:43740568
357 7008-7012 Gene denotes ACE2 Gene:59272
358 7208-7212 Gene denotes ACE2 Gene:59272
359 7363-7396 Gene denotes capsid-distal S1 and –proximal S2
360 7571-7575 Gene denotes ACE2 Gene:59272
361 7743-7747 Gene denotes ACE2 Gene:59272
362 7801-7807 Gene denotes ADAM17 Gene:6868
363 7817-7821 Gene denotes ACE2 Gene:59272
364 7878-7883 Gene denotes furin Gene:5045
365 7969-7973 Gene denotes ACE2 Gene:59272
366 8308-8312 Gene denotes ACE2 Gene:59272
367 8438-8442 Gene denotes ACE2 Gene:59272
368 8513-8518 Gene denotes B0AT1 Gene:340024
369 8535-8539 Gene denotes ACE2 Gene:59272
370 8591-8595 Gene denotes ACE2 Gene:59272
371 8667-8671 Gene denotes ACE2 Gene:59272
372 8704-8708 Gene denotes ACE2 Gene:59272
373 8890-8894 Gene denotes ACE2 Gene:59272
374 8928-8932 Gene denotes ACE2 Gene:59272
375 9144-9148 Gene denotes ACE2 Gene:59272
376 9175-9181 Gene denotes ADAM17 Gene:6868
377 9182-9186 Gene denotes TACE Gene:6868
378 9296-9300 Gene denotes ACE2 Gene:59272
379 9365-9369 Gene denotes ACE2 Gene:59272
380 9424-9428 Gene denotes ACE2 Gene:59272
381 9478-9483 Gene denotes B0AT1 Gene:340024
382 9775-9782 Gene denotes TMPRSS2 Gene:7113
383 9814-9818 Gene denotes ACE2 Gene:59272
384 9808-9813 Gene denotes spike Gene:43740568
385 8639-8644 Gene denotes spike Gene:43740568
386 8561-8566 Gene denotes spike Gene:43740568
387 7921-7926 Gene denotes spike Gene:43740568
388 7460-7465 Gene denotes Spike Gene:43740568
389 7356-7361 Gene denotes spike Gene:43740568
390 7303-7308 Gene denotes spike Gene:43740568
391 7192-7197 Gene denotes spike Gene:43740568
392 7091-7100 Species denotes SARS-CoVs Tax:694009
393 7278-7294 Species denotes SARS coronavirus Tax:694009
394 7479-7484 Species denotes clove Tax:219868
395 8163-8171 Species denotes SARS-CoV Tax:694009
396 8293-8303 Species denotes SARS-CoV-2 Tax:2697049
397 8432-8437 Species denotes human Tax:9606
398 9570-9578 Species denotes SARS-CoV Tax:694009
399 7764-7769 Gene denotes spike Gene:43740568
400 7238-7246 Disease denotes infected MESH:D007239
401 8118-8127 Disease denotes infection MESH:D007239
402 8188-8197 Disease denotes infection MESH:D007239
403 9898-9907 Disease denotes infection MESH:D007239
437 10042-10046 Gene denotes ACE2 Gene:59272
438 10203-10207 Gene denotes ACE2 Gene:59272
439 10314-10318 Gene denotes ACE2 Gene:59272
440 10716-10720 Gene denotes ACE2 Gene:59272
441 11622-11626 Gene denotes ACE2 Gene:59272
442 12083-12087 Gene denotes ACE2 Gene:59272
443 12271-12276 Gene denotes spike Gene:43740568
444 12201-12206 Gene denotes spike Gene:43740568
445 10032-10037 Gene denotes spike Gene:43740568
446 10020-10028 Species denotes patients Tax:9606
447 10380-10390 Species denotes SARS-CoV-2 Tax:2697049
448 10448-10458 Species denotes SARS-CoV-2 Tax:2697049
449 10552-10562 Species denotes SARS-CoV-2 Tax:2697049
450 10870-10878 Species denotes SARS-CoV Tax:694009
451 10879-10887 Species denotes patients Tax:9606
452 11083-11091 Species denotes SARS-CoV Tax:694009
453 11169-11177 Species denotes patients Tax:9606
454 11245-11253 Species denotes patients Tax:9606
455 11433-11441 Species denotes patients Tax:9606
456 11522-11530 Species denotes patients Tax:9606
457 11593-11601 Species denotes children Tax:9606
458 11989-11999 Species denotes SARS-CoV-2 Tax:2697049
459 12154-12164 Species denotes SARS-CoV-2 Tax:2697049
460 12480-12493 Species denotes coronaviruses Tax:11118
461 10002-10010 Disease denotes COVID-19 MESH:C000657245
462 10011-10019 Disease denotes infected MESH:D007239
463 11236-11244 Disease denotes COVID-19 MESH:C000657245
464 11322-11330 Disease denotes COVID-19 MESH:C000657245
465 11405-11422 Disease denotes SARS-CoV infected MESH:C000657245
466 11658-11674 Disease denotes Kawasaki disease MESH:D009080
467 12523-12532 Disease denotes infection MESH:D007239
468 12678-12686 Disease denotes COVID-19 MESH:C000657245
469 12758-12766 Disease denotes COVID-19 MESH:C000657245
471 12816-12820 Gene denotes ACE2 Gene:59272
497 12842-12845 Gene denotes ACE Gene:59272
498 12850-12854 Gene denotes ACE2 Gene:59272
499 12965-12969 Gene denotes ACE2 Gene:59272
500 13115-13125 Gene denotes bradykinin Gene:3827
501 13142-13153 Gene denotes B1 receptor Gene:623
502 13180-13188 Gene denotes Ang (1–9 Gene:284
503 13224-13257 Gene denotes ACE/Ang II/Ang II type 1 receptor Gene:1636
504 13259-13263 Gene denotes AT1R Gene:185
505 13436-13457 Gene denotes nitric oxide synthase Gene:4843
506 13699-13702 Gene denotes ACE Gene:59272
507 13718-13722 Gene denotes ACE2 Gene:59272
508 13763-13767 Gene denotes AT1R Gene:185
509 13993-13997 Gene denotes ACE2 Gene:59272
510 14156-14160 Gene denotes ACE2 Gene:59272
511 14124-14127 Gene denotes ACE Gene:59272
512 13166-13174 Gene denotes Ang (1–7 Gene:284
513 13026-13034 Gene denotes Ang (1–7 Gene:284
514 13381-13384 Gene denotes AT2 Gene:186
515 13756-13762 Gene denotes Ang II Gene:24179
516 13813-13824 Chemical denotes aldosterone MESH:D000450
517 13311-13322 Disease denotes hypotension MESH:D007022
518 13656-13667 Disease denotes dysfunction MESH:D009461
519 13826-13838 Disease denotes inflammation MESH:D007249
520 13870-13880 Disease denotes thrombosis MESH:D013927
521 13882-13901 Disease denotes cardiac dysfunction MESH:D006331
739 14295-14299 Gene denotes ACE2 Gene:59272
740 14628-14632 Gene denotes AT1R Gene:185
741 14771-14783 Gene denotes Mas receptor Gene:116511
742 14785-14789 Gene denotes MasR Gene:116511
743 14818-14826 Gene denotes Ang (1–7 Gene:305843
744 15179-15183 Gene denotes ACE2 Gene:70008
745 15419-15423 Gene denotes ACE2 Gene:70008
746 15689-15693 Gene denotes ACE2 Gene:302668
747 15858-15862 Gene denotes ACE2 Gene:302668
748 16297-16301 Gene denotes AT1R Gene:24180
749 16366-16374 Gene denotes Ang (1–9 Gene:305843
750 16391-16395 Gene denotes AT2R Gene:24182
751 16485-16489 Gene denotes AT2R Gene:24182
752 16515-16519 Gene denotes AT2R Gene:24182
753 16678-16682 Gene denotes AT2R Gene:24182
754 16705-16709 Gene denotes AT1R Gene:11610
755 17109-17113 Gene denotes ACE2 Gene:59272
756 17216-17220 Gene denotes ACE2 Gene:59272
757 17356-17360 Gene denotes ACE2 Gene:59272
758 17389-17393 Gene denotes ACE2 Gene:59272
759 17466-17471 Gene denotes IL-1β Gene:3552
760 17537-17541 Gene denotes CD34 Gene:947
761 17550-17554 Gene denotes MasR Gene:116511
762 17570-17574 Gene denotes ACE2 Gene:59272
763 17795-17798 Gene denotes ACE Gene:59272
764 17803-17807 Gene denotes ACE2 Gene:59272
765 17841-17845 Gene denotes ACE2 Gene:59272
766 17881-17884 Gene denotes ACE Gene:59272
767 17912-17916 Gene denotes AT1R Gene:185
768 17956-17959 Gene denotes ACE Gene:59272
769 17964-17968 Gene denotes ACE2 Gene:59272
770 18210-18213 Gene denotes ACE Gene:59272
771 18218-18222 Gene denotes ACE2 Gene:59272
772 18441-18445 Gene denotes ACE2 Gene:70008
773 18456-18460 Gene denotes MasR Gene:116511
774 18485-18488 Gene denotes ACE Gene:70008
775 18549-18554 Gene denotes Ren-2 Gene:19702
776 18607-18612 Gene denotes Ren-2 Gene:19702
777 18826-18831 Gene denotes renin Gene:24715
778 18874-18877 Gene denotes ACE Gene:302668
779 18881-18885 Gene denotes ACE2 Gene:302668
780 19035-19040 Gene denotes renin Gene:24715
781 19075-19081 Gene denotes Ang II Gene:24179
782 19415-19419 Gene denotes MasR Gene:116511
783 19521-19525 Gene denotes ACE2 Gene:302668
784 19526-19534 Gene denotes Ang (1–7 Gene:305843
785 19820-19825 Gene denotes renin Gene:5972
786 19845-19848 Gene denotes ACE Gene:59272
787 19853-19857 Gene denotes ACE2 Gene:59272
788 19912-19920 Gene denotes Ang (1–9 Gene:284
789 19942-19945 Gene denotes ACE Gene:59272
790 20031-20039 Gene denotes Ang (1–9 Gene:305843
791 20041-20045 Gene denotes AT2R Gene:24182
792 20056-20064 Gene denotes Ang (1–5 Gene:305843
793 20139-20143 Gene denotes MasR Gene:116511
794 20209-20217 Gene denotes Ang (1–5 Gene:305843
795 20386-20390 Gene denotes ACE2 Gene:59272
796 20457-20465 Gene denotes Ang (1–7 Gene:284
797 20497-20500 Gene denotes Bax Gene:581
798 20637-20645 Gene denotes Ang (1–7 Gene:305843
799 20793-20798 Gene denotes TNF-α Gene:24835
800 20803-20807 Gene denotes IL-6 Gene:24498
801 21003-21007 Gene denotes ACE2 Gene:302668
802 21101-21105 Gene denotes MasR Gene:116511
803 21152-21156 Gene denotes ACE2 Gene:302668
804 21272-21276 Gene denotes ACE2 Gene:59272
805 21541-21545 Gene denotes ACE2 Gene:70008
806 21869-21873 Gene denotes ACE2 Gene:70008
807 21886-21894 Gene denotes Ang (1–7 Gene:11727
808 21930-21934 Gene denotes ACE2 Gene:70008
809 21977-21981 Gene denotes ACE2 Gene:70008
810 22010-22014 Gene denotes ACE2 Gene:70008
811 22062-22066 Gene denotes ACE2 Gene:70008
812 22126-22134 Gene denotes Ang (1–7 Gene:11727
813 22449-22453 Gene denotes ACE2 Gene:70008
814 22489-22493 Gene denotes ACE2 Gene:70008
815 22627-22632 Gene denotes IL-10 Gene:16153
816 22692-22697 Gene denotes IL-10 Gene:16153
817 22749-22753 Gene denotes MasR Gene:116511
818 22779-22784 Gene denotes IL-10 Gene:16153
819 22834-22846 Gene denotes AT2 receptor Gene:11609
820 22910-22915 Gene denotes IL-10 Gene:16153
821 23102-23107 Gene denotes IL-10 Gene:16153
822 23368-23373 Gene denotes IL-10 Gene:16153
823 23464-23469 Gene denotes IL-10 Gene:3586
824 23505-23509 Gene denotes ACE2 Gene:59272
825 23646-23650 Gene denotes ACE2 Gene:59272
826 23651-23659 Gene denotes Ang (1–7 Gene:284
827 23681-23686 Gene denotes IL-10 Gene:3586
828 23386-23394 Gene denotes Ang (1–7 Gene:11727
829 22584-22592 Gene denotes Ang (1–7 Gene:11727
830 22285-22293 Gene denotes Ang (1–7 Gene:11727
831 22152-22160 Gene denotes Ang (1–7 Gene:11727
832 21091-21099 Gene denotes Ang (1–7 Gene:305843
833 20354-20362 Gene denotes Ang (1–7 Gene:284
834 20012-20020 Gene denotes Ang (1–7 Gene:305843
835 19968-19976 Gene denotes Ang (1–5 Gene:284
836 19923-19931 Gene denotes Ang (1–7 Gene:284
837 19405-19413 Gene denotes Ang (1–7 Gene:305843
838 18446-18454 Gene denotes Ang (1–7 Gene:11727
839 14702-14710 Gene denotes Ang (1–7 Gene:11727
840 14303-14311 Gene denotes Ang (1–7 Gene:284
841 23161-23164 Gene denotes Th2 Gene:15111
842 15668-15671 Gene denotes MLN Gene:100126231
843 14462-14467 Species denotes human Tax:9606
844 14717-14721 Species denotes mice Tax:10090
845 14922-14926 Species denotes rats Tax:10116
846 15140-15155 Species denotes Transgenic mice Tax:10090
847 15424-15439 Species denotes transgenic mice Tax:10090
848 15570-15573 Species denotes rat Tax:10116
849 16278-16281 Species denotes rat Tax:10116
850 16472-16477 Species denotes mouse Tax:10090
851 17187-17192 Species denotes human Tax:9606
852 17295-17300 Species denotes human Tax:9606
853 17531-17536 Species denotes human Tax:9606
854 18040-18045 Species denotes human Tax:9606
855 18066-18074 Species denotes patients Tax:9606
856 18566-18570 Species denotes rats Tax:10116
857 18601-18606 Species denotes mouse Tax:10090
858 18676-18680 Species denotes rats Tax:10116
859 18747-18751 Species denotes rats Tax:10116
860 19204-19207 Species denotes rat Tax:10116
861 19440-19443 Species denotes rat Tax:10116
862 19728-19736 Species denotes patients Tax:9606
863 20177-20180 Species denotes rat Tax:10116
864 20258-20277 Species denotes Sprague-Dawley rats Tax:10116
865 20312-20320 Species denotes patients Tax:9606
866 20657-20668 Species denotes Wistar rats Tax:10116
867 21251-21261 Species denotes SARS-CoV-2 Tax:2697049
868 21524-21528 Species denotes mice Tax:10090
869 22387-22393 Species denotes murine Tax:10090
870 22798-22803 Species denotes mouse Tax:10090
871 23758-23766 Species denotes patients Tax:9606
872 18555-18565 Species denotes transgenic Tax:10090
873 18716-18721 Gene denotes renin Gene:5972
874 18613-18618 Gene denotes renin Gene:5972
875 21510-21515 Gene denotes spike Gene:43740568
876 22652-22656 Gene denotes MasR Gene:116511
877 22295-22299 Gene denotes MasR Gene:116511
878 20022-20026 Gene denotes MasR Gene:116511
879 21901-21907 Gene denotes Ang II Gene:24179
880 21875-21881 Gene denotes Ang II Gene:24179
881 21530-21536 Gene denotes Ang II Gene:24179
882 19904-19910 Gene denotes Ang II Gene:24179
883 18489-18495 Gene denotes Ang II Gene:24179
884 17894-17900 Gene denotes Ang II Gene:24179
885 16617-16623 Gene denotes Ang II Gene:24179
886 16083-16089 Gene denotes Ang II Gene:24179
887 14621-14627 Gene denotes Ang II Gene:24179
888 15664-15667 Chemical denotes C16
889 16532-16539 Chemical denotes PD12319
890 22870-22882 Chemical denotes nitric oxide MESH:D009569
891 14387-14412 Disease denotes inflammation of the renal MESH:D007249
892 14441-14460 Disease denotes cardiac dysfunction MESH:D006331
893 14468-14477 Disease denotes cirrhosis MESH:D005355
894 14482-14493 Disease denotes lung injury MESH:D055370
895 14494-14502 Disease denotes fibrosis MESH:D005355
896 14886-14905 Disease denotes cardiac hypertrophy MESH:D006332
897 14910-14918 Disease denotes fibrosis MESH:D005355
898 15046-15068 Disease denotes myocardial dysfunction MESH:D009202
899 15216-15238 Disease denotes ventricular arrhythmia MESH:D001145
900 15240-15251 Disease denotes heart block MESH:D006327
901 15253-15276 Disease denotes ventricular tachycardia MESH:D017180
902 15290-15314 Disease denotes ventricular fibrillation MESH:D014693
903 15462-15470 Disease denotes fibrosis MESH:D005355
904 15583-15604 Disease denotes myocardial infarction MESH:D009203
905 15740-15748 Disease denotes fibrosis MESH:D005355
906 15753-15792 Disease denotes hypertrophy of non-infarcted myocardium MESH:D006984
907 15910-15937 Disease denotes myocardial infarction heart MESH:D009203
908 15965-15987 Disease denotes cardiovascular disease MESH:D002318
909 16071-16081 Disease denotes thrombosis MESH:D013927
910 16094-16114 Disease denotes hypercholesterolemia MESH:D006937
911 16157-16167 Disease denotes thrombosis MESH:D013927
912 16330-16340 Disease denotes thrombosis MESH:D013927
913 16344-16364 Disease denotes platelet aggregation MESH:D001791
914 16432-16442 Disease denotes thrombotic MESH:D013927
915 16588-16598 Disease denotes thrombosis MESH:D013927
916 16755-16765 Disease denotes thrombosis MESH:D013927
917 16780-16818 Disease denotes disseminated intravascular coagulation MESH:D004211
918 16838-16881 Disease denotes hypoproteinaemia and deficit of coagulation MESH:D001778
919 16941-16951 Disease denotes renal loss MESH:D051437
920 16968-16979 Disease denotes proteinuria MESH:D011507
921 17193-17214 Disease denotes hepatitis C cirrhosis MESH:D006526
922 17325-17343 Disease denotes hypoxic conditions MESH:D000071069
923 17451-17458 Disease denotes hypoxia MESH:D000860
924 17668-17675 Disease denotes hypoxia MESH:D000860
925 17698-17753 Disease denotes hypoxic conditions human pulmonary artery smooth muscle MESH:D018235
926 18080-18119 Disease denotes ischaemic (local hypoxia) heart disease MESH:D003324
927 18229-18247 Disease denotes hypoxic conditions MESH:D000071069
928 18367-18374 Disease denotes hypoxia MESH:D000860
929 18411-18418 Disease denotes hypoxia MESH:D000860
930 18526-18548 Disease denotes pulmonary hypertensive MESH:D006976
931 18734-18746 Disease denotes hypertensive MESH:D006973
932 18809-18816 Disease denotes hypoxia MESH:D000860
933 18906-18924 Disease denotes hypoxic conditions MESH:D000071069
934 18939-18946 Disease denotes hypoxia MESH:D000860
935 18970-18981 Disease denotes hypercapnia MESH:D006935
936 19112-19132 Disease denotes hypercapnic acidosis MESH:D000138
937 19675-19682 Disease denotes hypoxia MESH:D000860
938 19683-19694 Disease denotes hypercapnia MESH:D006935
939 20326-20352 Disease denotes inflammatory bowel disease MESH:D015212
940 20829-20846 Disease denotes lung inflammation MESH:D011014
941 20850-20868 Disease denotes pulmonary fibrosis MESH:D011658
942 20952-20959 Disease denotes hypoxia MESH:D000860
943 20960-20971 Disease denotes hypercapnia MESH:D006935
944 20973-20980 Disease denotes Hypoxia MESH:D000860
945 21205-21213 Disease denotes COVID-19 MESH:C000657245
946 21389-21404 Disease denotes viral infection MESH:D001102
947 21713-21729 Disease denotes pulmonary oedema MESH:D011654
948 22314-22342 Disease denotes allergic airway inflammation MESH:D007249
949 22403-22409 Disease denotes asthma MESH:D001249
950 22473-22479 Disease denotes asthma MESH:D001249
951 22525-22540 Disease denotes asthma symptoms MESH:D051271
952 23225-23246 Disease denotes allergic inflammation MESH:D007249
953 23584-23592 Disease denotes COVID-19 MESH:C000657245
954 23720-23745 Disease denotes eosinopaenia/lymphopaenia
955 23749-23757 Disease denotes COVID-19 MESH:C000657245
1013 23925-23928 Gene denotes ACE Gene:59272
1014 23941-23945 Gene denotes ACE2 Gene:59272
1015 24218-24221 Gene denotes ACE Gene:302668
1016 24222-24226 Gene denotes ACE2 Gene:302668
1017 24263-24266 Gene denotes ACE Gene:302668
1018 24372-24376 Gene denotes ACE2 Gene:302668
1019 24507-24513 Gene denotes Ang II Gene:24179
1020 24628-24632 Gene denotes ACE2 Gene:302668
1021 24718-24722 Gene denotes ACE2 Gene:302668
1022 24754-24758 Gene denotes AT1R Gene:24180
1023 24880-24888 Gene denotes Ang (1–7 Gene:305843
1024 24933-24937 Gene denotes ACE2 Gene:302668
1025 25049-25057 Gene denotes Ang (1–7 Gene:305843
1026 25080-25084 Gene denotes AT1R Gene:24180
1027 25166-25174 Gene denotes Ang (1–7 Gene:305843
1028 25216-25222 Gene denotes Ang II Gene:24179
1029 25232-25236 Gene denotes ACE2 Gene:302668
1030 25321-25325 Gene denotes ACE2 Gene:302668
1031 25374-25382 Gene denotes Ang (1–7 Gene:305843
1032 25404-25408 Gene denotes ACE2 Gene:302668
1033 25648-25651 Gene denotes ACE Gene:302668
1034 25652-25656 Gene denotes ACE2 Gene:302668
1035 25774-25778 Gene denotes ACE2 Gene:302668
1036 25813-25817 Gene denotes MasR Gene:116511
1037 26067-26071 Gene denotes AT1R Gene:185
1038 26101-26105 Gene denotes MasR Gene:116511
1039 26362-26366 Gene denotes ACE2 Gene:59272
1040 26386-26394 Gene denotes Ang (1–7 Gene:284
1041 26463-26467 Gene denotes ACE2 Gene:59272
1042 26551-26555 Gene denotes ACE2 Gene:59272
1043 25001-25009 Gene denotes Ang-(1–7 Gene:305843
1044 26247-26255 Gene denotes Ang (1–7 Gene:284
1045 26091-26099 Gene denotes Ang (1–7 Gene:284
1046 25803-25811 Gene denotes Ang (1–7 Gene:305843
1047 24494-24502 Gene denotes Ang (1–7 Gene:305843
1048 26579-26584 Gene denotes spike Gene:43740568
1049 26411-26415 Gene denotes MasR Gene:116511
1050 25106-25110 Gene denotes MasR Gene:116511
1051 24977-24981 Gene denotes MasR Gene:116511
1052 23967-23972 Species denotes human Tax:9606
1053 24420-24424 Species denotes rats Tax:10116
1054 24593-24597 Species denotes rats Tax:10116
1055 24839-24842 Species denotes rat Tax:10116
1056 26225-26235 Species denotes SARS-CoV-2 Tax:2697049
1057 26585-26595 Species denotes SARS-CoV-2 Tax:2697049
1058 26257-26263 Gene denotes Ang II Gene:24179
1059 26060-26066 Gene denotes Ang II Gene:24179
1060 25296-25302 Gene denotes Ang II Gene:24179
1061 25073-25079 Gene denotes Ang II Gene:24179
1062 24904-24910 Gene denotes Ang II Gene:24179
1063 24697-24703 Gene denotes Ang II Gene:24179
1064 24599-24605 Gene denotes Ang II Gene:24179
1065 23853-23871 Disease denotes hypoxic conditions MESH:D000071069
1066 24159-24166 Disease denotes hypoxia MESH:D000860
1067 25949-25956 Disease denotes hypoxia MESH:D000860
1068 25957-25977 Disease denotes SARS-CoV-2 infection MESH:C000657245
1069 26149-26167 Disease denotes hypoxic conditions MESH:D000071069
1071 26648-26656 Disease denotes COVID-19 MESH:C000657245
1078 29005-29010 Gene denotes IL-1β Gene:3552
1079 29015-29020 Gene denotes TNF-α Gene:7124
1080 29092-29096 Gene denotes ACE2 Gene:59272
1081 29133-29137 Gene denotes ACE2 Gene:59272
1082 28985-28993 Species denotes SARS-CoV Tax:694009
1083 29175-29190 Disease denotes viral infection MESH:D001102
1097 29442-29447 Gene denotes renin Gene:5972
1098 29449-29452 Gene denotes ACE Gene:59272
1099 29457-29461 Gene denotes ACE2 Gene:59272
1100 29532-29540 Gene denotes Ang (1–9 Gene:284
1101 29543-29551 Gene denotes Ang (1–5 Gene:284
1102 29581-29591 Gene denotes bradykinin Gene:3827
1103 29623-29627 Gene denotes ACE2 Gene:59272
1104 29521-29529 Gene denotes Ang (1–7 Gene:284
1105 29660-29670 Species denotes SARS-CoV-2 Tax:2697049
1106 29405-29410 Gene denotes renin Gene:5972
1107 29513-29519 Gene denotes Ang II Gene:24179
1108 29310-29317 Disease denotes Hypoxia MESH:D000860
1109 29345-29356 Disease denotes hypercapnia MESH:D006935
1119 29682-29686 Gene denotes ACE2 Gene:59272
1120 29794-29797 Gene denotes ACE Gene:59272
1121 29837-29843 Gene denotes Ang II Gene:24179
1122 29850-29854 Gene denotes ACE2 Gene:59272
1123 29877-29885 Gene denotes Ang (1–7 Gene:284
1124 29784-29789 Gene denotes renin Gene:5972
1125 29736-29742 Gene denotes Ang II Gene:24179
1126 29713-29724 Disease denotes hypotensive MESH:D007022
1127 29755-29766 Disease denotes Hypotension MESH:D007022
1136 29903-29911 Gene denotes Ang (1–7 Gene:284
1137 29979-29984 Gene denotes IL-10 Gene:3586
1138 30272-30277 Gene denotes IL-10 Gene:3586
1139 30215-30223 Gene denotes Ang (1–7 Gene:284
1140 29998-30027 Disease denotes eosinopaenia and lymphopaenia
1141 30141-30156 Disease denotes virus infection MESH:D001102
1142 30203-30213 Disease denotes infections MESH:D007239
1143 30357-30377 Disease denotes SARS-CoV-2 infection MESH:C000657245
1152 30383-30391 Gene denotes Ang (1–7 Gene:284
1153 30393-30397 Gene denotes MasR Gene:116511
1154 30418-30422 Gene denotes ACE2 Gene:59272
1155 30534-30538 Gene denotes AT1R Gene:185
1156 30567-30571 Gene denotes ACE2 Gene:59272
1157 30527-30533 Gene denotes Ang II Gene:24179
1158 30484-30490 Gene denotes Ang II Gene:24179
1159 30503-30510 Disease denotes hypoxia MESH:D000860
1164 30601-30609 Gene denotes Ang (1–7 Gene:284
1165 30611-30615 Gene denotes MasR Gene:116511
1166 30636-30655 Disease denotes cardiac dysfunction MESH:D006331
1167 30696-30703 Disease denotes hypoxia MESH:D000860
1175 30788-30792 Gene denotes ACE2 Gene:59272
1176 30900-30904 Gene denotes ACE2 Gene:59272
1177 30952-30960 Gene denotes Ang (1–9 Gene:284
1178 30979-30982 Gene denotes AT2 Gene:186
1179 30853-30859 Gene denotes Ang II Gene:24179
1180 31031-31041 Disease denotes thrombosis MESH:D013927
1181 31052-31070 Disease denotes hypoxic conditions MESH:D000071069
1231 26763-26767 Gene denotes ACE2 Gene:59272
1232 26867-26871 Gene denotes ACE2 Gene:59272
1233 26935-26939 Gene denotes ACE2 Gene:59272
1234 27127-27131 Gene denotes ACE2 Gene:59272
1235 27326-27332 Gene denotes ADAM17 Gene:6868
1236 27333-27337 Gene denotes TACE Gene:6868
1237 27352-27356 Gene denotes ACE2 Gene:59272
1238 27370-27375 Gene denotes TNF-α Gene:7124
1239 27434-27438 Gene denotes ACE2 Gene:59272
1240 27697-27702 Gene denotes TNF-α Gene:7124
1241 27707-27712 Gene denotes IL-1β Gene:3552
1242 27794-27798 Gene denotes ACE2 Gene:59272
1243 27871-27875 Gene denotes ACE2 Gene:59272
1244 27957-27962 Gene denotes TNF-α Gene:7124
1245 27967-27972 Gene denotes IL-1β Gene:3552
1246 28030-28034 Gene denotes ACE2 Gene:59272
1247 28093-28098 Gene denotes IL-1β Gene:3552
1248 28190-28195 Gene denotes TNF-α Gene:7124
1249 28200-28205 Gene denotes IL-1β Gene:3552
1250 28289-28295 Gene denotes ADAM17 Gene:6868
1251 28384-28389 Gene denotes TNF-α Gene:7124
1252 28461-28466 Gene denotes TNF-α Gene:7124
1253 28533-28539 Gene denotes ADAM17 Gene:6868
1254 28540-28544 Gene denotes TACE Gene:6868
1255 28593-28597 Gene denotes ACE2 Gene:59272
1256 28640-28646 Gene denotes ADAM17 Gene:6868
1257 28647-28651 Gene denotes TACE Gene:6868
1258 28824-28828 Gene denotes ACE2 Gene:59272
1259 28833-28838 Gene denotes TNF-α Gene:7124
1260 28878-28882 Gene denotes ACE2 Gene:59272
1261 26917-26922 Gene denotes spike Gene:43740568
1262 26771-26781 Species denotes SARS-CoV-2 Tax:2697049
1263 26883-26891 Species denotes SARS-CoV Tax:694009
1264 27012-27020 Species denotes SARS-CoV Tax:694009
1265 27073-27076 Species denotes CoV Tax:11118
1266 27292-27300 Species denotes SARS-CoV Tax:694009
1267 27307-27310 Species denotes CoV Tax:11118
1268 27550-27560 Species denotes SARS-CoV-2 Tax:2697049
1269 27572-27580 Species denotes SARS-CoV Tax:694009
1270 27750-27760 Species denotes SARS-CoV-2 Tax:2697049
1271 28332-28340 Species denotes SARS-CoV Tax:694009
1272 28728-28736 Species denotes SARS-CoV Tax:694009
1273 27068-27072 Species denotes NL63 Tax:277944
1274 27302-27306 Species denotes NL63 Tax:277944
1275 27593-27598 Gene denotes furin Gene:5045
1276 28853-28858 Gene denotes spike Gene:43740568
1277 27042-27062 Disease denotes respiratory symptoms MESH:D012818
1278 28369-28378 Disease denotes infection MESH:D007239
1279 28426-28444 Disease denotes SARS-CoV infection MESH:C000657245
1302 31138-31142 Gene denotes ACE2 Gene:59272
1303 31176-31180 Gene denotes ACE2 Gene:59272
1304 31494-31498 Gene denotes ACE2 Gene:59272
1305 31557-31561 Gene denotes ACE2 Gene:59272
1306 31715-31719 Gene denotes ACE2 Gene:59272
1307 32211-32219 Gene denotes Ang (1–9 Gene:284
1308 32262-32273 Gene denotes B1 receptor Gene:623
1309 32306-32310 Gene denotes ACE2 Gene:59272
1310 32340-32350 Gene denotes bradykinin Gene:3827
1311 32363-32373 Gene denotes bradykinin Gene:3827
1312 32389-32393 Gene denotes ACE2 Gene:59272
1313 31657-31662 Gene denotes mACE2 Gene:70008
1314 32189-32197 Gene denotes Ang (1–7 Gene:284
1315 31150-31160 Species denotes SARS-CoV-2 Tax:2697049
1316 31617-31627 Species denotes SARS-CoV-2 Tax:2697049
1317 31959-31969 Species denotes SARS-CoV-2 Tax:2697049
1318 32200-32206 Gene denotes Ang II Gene:24179
1319 32329-32336 Chemical denotes des-Arg
1320 32431-32443 Chemical denotes casomorphins
1321 31582-31589 Disease denotes hypoxia MESH:D000860
1322 31590-31601 Disease denotes hypotension MESH:D007022
1323 32153-32161 Disease denotes COVID-19 MESH:C000657245
1329 32896-32903 Gene denotes TMPRSS2 Gene:7113
1330 32908-32914 Gene denotes ADAM17 Gene:6868
1331 32945-32950 Gene denotes renin Gene:5972
1332 32952-32955 Gene denotes ACE Gene:59272
1333 32960-32964 Gene denotes ACE2 Gene:59272
1346 33108-33115 Gene denotes TMPRSS2 Gene:7113
1347 33120-33126 Gene denotes ADAM17 Gene:6868
1348 33187-33194 Gene denotes TMPRSS2 Gene:7113
1349 33348-33354 Gene denotes ADAM17 Gene:6868
1350 33471-33477 Gene denotes ADAM17 Gene:6868
1351 33487-33491 Gene denotes ACE2 Gene:59272
1352 33534-33538 Gene denotes ACE2 Gene:59272
1353 33660-33664 Gene denotes ACE2 Gene:59272
1354 33909-33913 Gene denotes ACE2 Gene:59272
1355 33210-33220 Species denotes SARS-CoV-2 Tax:2697049
1356 33171-33177 Chemical denotes serine MESH:D012694
1357 33794-33802 Disease denotes COVID-19 MESH:C000657245
1367 34308-34312 Gene denotes ACE2 Gene:59272
1368 34358-34361 Gene denotes ACE Gene:59272
1369 34399-34403 Gene denotes MasR Gene:116511
1370 34427-34431 Gene denotes ACE2 Gene:59272
1371 34433-34436 Gene denotes ACE Gene:59272
1372 34441-34446 Gene denotes renin Gene:5972
1373 34586-34590 Gene denotes MasR Gene:116511
1374 34348-34353 Gene denotes renin Gene:5972
1375 34493-34502 Species denotes SARS-CoVs Tax:694009
1422 34830-34838 Gene denotes Ang-(1–7 Gene:284
1423 35049-35057 Gene denotes Ang-(1–7 Gene:284
1424 35137-35141 Gene denotes ACE2 Gene:59272
1425 35241-35245 Gene denotes ACE2 Gene:59272
1426 35350-35354 Gene denotes iNOS Gene:4843
1427 35387-35393 Gene denotes Ang II Gene:24179
1428 35418-35426 Gene denotes Ang (1–7 Gene:284
1429 35609-35614 Gene denotes rACE2 Gene:302668
1430 35795-35803 Gene denotes Ang (1–7 Gene:11727
1431 35809-35813 Gene denotes MasR Gene:116511
1432 36962-36966 Gene denotes ACE2 Gene:59272
1433 34770-34778 Gene denotes Ang-(1–7 Gene:284
1434 34749-34757 Gene denotes Ang-(1–7 Gene:284
1435 35075-35083 Gene denotes Ang (1–5 Gene:284
1436 36921-36925 Gene denotes MasR Gene:116511
1437 36864-36868 Gene denotes MasR Gene:116511
1438 36681-36685 Gene denotes MasR Gene:116511
1439 35470-35474 Gene denotes MasR Gene:116511
1440 35164-35168 Gene denotes MasR Gene:116511
1441 34991-34995 Gene denotes MasR Gene:116511
1442 34912-34916 Gene denotes MasR Gene:116511
1443 34797-34801 Gene denotes MasR Gene:116511
1444 35724-35729 Gene denotes rACE2 Gene:302668
1445 34874-34879 Species denotes human Tax:9606
1446 35264-35269 Species denotes human Tax:9606
1447 35455-35459 Species denotes mice Tax:10090
1448 35877-35881 Species denotes rats Tax:10116
1449 36460-36463 Species denotes rat Tax:10116
1450 36773-36777 Species denotes mice Tax:10090
1451 36781-36785 Species denotes rats Tax:10116
1452 36826-36832 Species denotes humans Tax:9606
1453 37013-37021 Species denotes patients Tax:9606
1454 34698-34710 Gene denotes Mas receptor Gene:116511
1455 34640-34652 Gene denotes Mas receptor Gene:116511
1456 36221-36227 Gene denotes Ang II Gene:24179
1457 36082-36088 Gene denotes Ang II Gene:24179
1458 35749-35755 Gene denotes Ang II Gene:24179
1459 35631-35637 Gene denotes Ang II Gene:24179
1460 35246-35259 Disease denotes hyperactivity MESH:D006948
1461 35578-35589 Disease denotes hypotensive MESH:D007022
1462 35700-35711 Disease denotes hypotensive MESH:D007022
1463 35864-35876 Disease denotes hypertensive MESH:D006973
1464 36090-36102 Disease denotes renal injury MESH:D007674
1465 36473-36491 Disease denotes cardiac arrhythmia MESH:D001145
1466 36581-36591 Disease denotes arrhythmic MESH:D001145
1467 37004-37012 Disease denotes COVID-19 MESH:C000657245
1471 37119-37123 Gene denotes ACE2 Gene:59272
1472 37129-37132 Gene denotes ACE Gene:59272
1473 37134-37147 Disease denotes Hyperactivity MESH:D006948
1488 37180-37184 Gene denotes ACE2 Gene:59272
1489 37189-37192 Gene denotes ACE Gene:59272
1490 37276-37280 Gene denotes ACE2 Gene:59272
1491 37376-37379 Gene denotes ACE Gene:59272
1492 37467-37471 Gene denotes ACE2 Gene:59272
1493 37620-37630 Gene denotes bradykinin Gene:3827
1494 37920-37924 Gene denotes ACE2 Gene:59272
1495 38101-38105 Gene denotes ACE2 Gene:59272
1496 38253-38261 Gene denotes Ang (1–7 Gene:284
1497 38295-38299 Gene denotes MasR Gene:116511
1498 37428-37437 Chemical denotes dipeptide MESH:D004151
1499 37522-37529 Chemical denotes proline MESH:D011392
1500 37749-37760 Disease denotes hypotensive MESH:D007022
1501 38359-38370 Disease denotes hypotension MESH:D007022
1576 38398-38402 Gene denotes ACE2 Gene:59272
1577 38415-38418 Gene denotes ACE Gene:59272
1578 38841-38844 Gene denotes ACE Gene:59272
1579 38849-38853 Gene denotes ACE2 Gene:59272
1580 38882-38890 Gene denotes Ang (1–9 Gene:284
1581 38907-38913 Gene denotes Ang II Gene:24179
1582 38926-38930 Gene denotes ACE2 Gene:59272
1583 38974-38978 Gene denotes ACE2 Gene:59272
1584 39760-39764 Gene denotes ACE2 Gene:59272
1585 41434-41437 Gene denotes ACE Gene:59272
1586 41442-41446 Gene denotes ACE2 Gene:59272
1587 41648-41661 Gene denotes serum albumin Gene:213
1588 42139-42143 Gene denotes ACE2 Gene:59272
1589 42383-42387 Gene denotes ACE2 Gene:59272
1590 39477-39484 Gene denotes albumin Gene:213
1591 42798-42805 Gene denotes albumin Gene:213
1592 42696-42703 Gene denotes albumin Gene:213
1593 42293-42300 Gene denotes albumin Gene:213
1594 41808-41815 Gene denotes albumin Gene:213
1595 41293-41300 Gene denotes albumin Gene:213
1596 40447-40454 Gene denotes albumin Gene:213
1597 40243-40250 Gene denotes albumin Gene:213
1598 40061-40068 Gene denotes albumin Gene:213
1599 39941-39948 Gene denotes albumin Gene:213
1600 39893-39900 Gene denotes albumin Gene:213
1601 39834-39841 Gene denotes albumin Gene:213
1602 39079-39087 Species denotes patients Tax:9606
1603 39281-39289 Species denotes patients Tax:9606
1604 39558-39568 Species denotes SARS-CoV-2 Tax:2697049
1605 40217-40225 Species denotes patients Tax:9606
1606 40399-40407 Species denotes patients Tax:9606
1607 41531-41539 Species denotes patients Tax:9606
1608 41937-41945 Species denotes patients Tax:9606
1609 41973-41981 Species denotes patients Tax:9606
1610 42234-42242 Species denotes patients Tax:9606
1611 42618-42626 Species denotes patients Tax:9606
1612 42730-42738 Species denotes patients Tax:9606
1613 42785-42793 Species denotes patients Tax:9606
1614 40924-40929 Species denotes human Tax:9606
1615 38871-38877 Gene denotes Ang II Gene:24179
1616 40747-40754 Gene denotes albumin Gene:213
1617 38486-38490 Chemical denotes EDTA MESH:D004492
1618 38531-38539 Chemical denotes chloride MESH:D002712
1619 38543-38551 Chemical denotes fluoride MESH:D005459
1620 38610-38618 Chemical denotes chloride MESH:D002712
1621 38799-38807 Chemical denotes chloride MESH:D002712
1622 38948-38956 Chemical denotes chloride MESH:D002712
1623 39089-39097 Chemical denotes chloride MESH:D002712
1624 41180-41185 Chemical denotes metal MESH:D008670
1625 41199-41203 Chemical denotes iron MESH:D007501
1626 41567-41578 Chemical denotes Ang peptide
1627 42482-42486 Chemical denotes Zn2+
1628 42580-42584 Chemical denotes Zn2+
1629 39070-39078 Disease denotes COVID–19 MESH:C000657245
1630 39272-39280 Disease denotes COVID-19 MESH:C000657245
1631 39587-39622 Disease denotes adult respiratory distress syndrome MESH:D012128
1632 39624-39628 Disease denotes ARDS MESH:D012128
1633 39632-39640 Disease denotes COVID-19 MESH:C000657245
1634 39702-39728 Disease denotes inflammatory bowel disease MESH:D015212
1635 39730-39733 Disease denotes IBD MESH:D015212
1636 40212-40216 Disease denotes ARDS MESH:D012128
1637 40320-40336 Disease denotes hypoalbuminaemia
1638 40394-40398 Disease denotes ARDS MESH:D012128
1639 41526-41530 Disease denotes ARDS MESH:D012128
1640 41622-41626 Disease denotes ARDS MESH:D012128
1641 41672-41680 Disease denotes COVID-19 MESH:C000657245
1642 41910-41936 Disease denotes asthmatic/allergic disease MESH:D004342
1643 41950-41972 Disease denotes chronic kidney disease MESH:D051436
1644 42003-42025 Disease denotes cardiovascular disease MESH:D002318
1645 42063-42071 Disease denotes COVID-19 MESH:C000657245
1646 42212-42233 Disease denotes chronic renal disease MESH:D051436
1647 42400-42422 Disease denotes chronic renal diseases MESH:D051436
1648 42611-42617 Disease denotes asthma MESH:D001249
1649 42723-42729 Disease denotes asthma MESH:D001249
1699 43085-43089 Gene denotes ACE2 Gene:59272
1700 43094-43097 Gene denotes ACE Gene:59272
1701 43713-43718 Gene denotes IL-1β Gene:3552
1702 43720-43724 Gene denotes IL-6 Gene:3569
1703 43726-43730 Gene denotes IL-8 Gene:3576
1704 43735-43740 Gene denotes TNF-α Gene:7124
1705 43844-43849 Gene denotes TNF-α Gene:7124
1706 43878-43882 Gene denotes IL-6 Gene:3569
1707 43887-43891 Gene denotes IL-8 Gene:3576
1708 44480-44485 Gene denotes IL-1β Gene:3552
1709 44487-44491 Gene denotes IL-6 Gene:3569
1710 44493-44497 Gene denotes IL-8 Gene:3576
1711 44499-44504 Gene denotes TNF-α Gene:7124
1712 44540-44545 Gene denotes IL-10 Gene:3586
1713 44671-44676 Gene denotes IL-1β Gene:3552
1714 44678-44682 Gene denotes IL-2 Gene:3558
1715 44684-44688 Gene denotes IL-4 Gene:3565
1716 44690-44694 Gene denotes IL-6 Gene:3569
1717 44696-44700 Gene denotes IL-8 Gene:3576
1718 44702-44707 Gene denotes IL-10 Gene:3586
1719 44719-44724 Gene denotes TNF-α Gene:7124
1720 43300-43308 Species denotes patients Tax:9606
1721 43817-43825 Species denotes patients Tax:9606
1722 44616-44624 Species denotes SARS-CoV Tax:694009
1723 42877-42882 Chemical denotes ZnCl2 MESH:C016837
1724 42883-42903 Chemical denotes ZnO/hexachloroethane
1725 43146-43154 Chemical denotes chloride MESH:D002712
1726 43323-43328 Chemical denotes metal MESH:D008670
1727 43578-43588 Chemical denotes metal fume
1728 45197-45202 Chemical denotes ZnCl2 MESH:C016837
1729 42990-42994 Disease denotes ARDS MESH:D012128
1730 43050-43058 Disease denotes COVID-19 MESH:C000657245
1731 43249-43253 Disease denotes ARDS MESH:D012128
1732 43291-43299 Disease denotes COVID-19 MESH:C000657245
1733 43334-43339 Disease denotes fever MESH:D005334
1734 43341-43360 Disease denotes a flu-like syndrome MESH:D007251
1735 43466-43486 Disease denotes respiratory symptoms MESH:D012818
1736 43517-43526 Disease denotes pneumonia MESH:D011014
1737 43589-43594 Disease denotes fever MESH:D005334
1738 43621-43626 Disease denotes fever MESH:D005334
1739 43628-43635 Disease denotes fatigue MESH:D005221
1740 43637-43648 Disease denotes muscle ache MESH:D063806
1741 43650-43655 Disease denotes cough MESH:D003371
1742 43657-43664 Disease denotes dyspnea MESH:D004417
1743 43808-43816 Disease denotes COVID-19 MESH:C000657245
1744 44243-44251 Disease denotes COVID-19 MESH:C000657245
1745 44567-44598 Disease denotes pulmonary arterial hypertension MESH:D000081029
1746 44847-44851 Disease denotes ARDS MESH:D012128
1747 44861-44880 Disease denotes SARS-CoV infections MESH:C000657245
1771 45442-45467 Gene denotes Zrt- and Irt-like protein Gene:84619
1772 45469-45472 Gene denotes ZIP Gene:84619
1773 46811-46816 Gene denotes B0AT1 Gene:340024
1774 46856-46860 Gene denotes ACE2 Gene:59272
1775 46952-46959 Gene denotes insulin Gene:3630
1776 47081-47085 Gene denotes ACE2 Gene:59272
1777 47121-47125 Gene denotes ACE2 Gene:59272
1778 45932-45936 Species denotes rice Tax:4530
1779 46779-46784 Species denotes human Tax:9606
1780 45494-45498 Chemical denotes Zn2+
1781 45509-45513 Chemical denotes Cu2+
1782 45518-45522 Chemical denotes Fe2+
1783 45729-45739 Chemical denotes zinc oxide MESH:D015034
1784 45770-45788 Chemical denotes zinc chloride salt
1785 45960-45970 Chemical denotes folic acid MESH:D005492
1786 46100-46104 Chemical denotes Zn2+
1787 46214-46218 Chemical denotes Zn2+
1788 46247-46252 Chemical denotes amine MESH:D000588
1789 46264-46275 Chemical denotes carboxylate
1790 46381-46391 Chemical denotes ZnCl2 salt
1791 46395-46400 Chemical denotes Zn-AA
1792 46739-46746 Chemical denotes zinc-AA
1793 46892-46899 Chemical denotes zinc-AA
1800 47421-47434 Gene denotes serum albumin Gene:213
1801 47398-47402 Chemical denotes Zn2+
1802 47549-47553 Chemical denotes Zn2+
1803 47594-47598 Chemical denotes Zn2+
1804 47774-47778 Chemical denotes Zn2+
1805 47919-47923 Chemical denotes Zn2+
1875 48174-48177 Gene denotes ZIP Gene:84619
1876 49384-49387 Gene denotes ZIP Gene:84619
1877 49543-49546 Gene denotes ZIP Gene:84619
1878 49776-49783 Gene denotes albumin Gene:213
1879 50282-50289 Gene denotes albumin Gene:213
1880 50865-50875 Gene denotes fibrinogen Gene:2244
1881 51318-51325 Gene denotes albumin Gene:213
1882 50672-50679 Gene denotes albumin Gene:213
1883 50582-50589 Gene denotes albumin Gene:213
1884 50220-50227 Gene denotes albumin Gene:213
1885 49947-49954 Gene denotes albumin Gene:213
1886 49197-49205 Species denotes patients Tax:9606
1887 51733-51740 Species denotes patient Tax:9606
1888 52769-52777 Species denotes patients Tax:9606
1889 47994-47999 Chemical denotes metal MESH:D008670
1890 48155-48159 Chemical denotes Zn2+
1891 49239-49243 Chemical denotes Zn2+
1892 49286-49290 Chemical denotes Fe2+
1893 49295-49299 Chemical denotes Cu2+
1894 49355-49360 Chemical denotes metal MESH:D008670
1895 49502-49506 Chemical denotes Fe2+
1896 49534-49538 Chemical denotes Zn2+
1897 49632-49642 Chemical denotes EDTA metal
1898 49821-49826 Chemical denotes metal MESH:D008670
1899 49879-49894 Chemical denotes free fatty acid MESH:D005230
1900 49896-49899 Chemical denotes FFA MESH:D005230
1901 49988-49993 Chemical denotes metal MESH:D008670
1902 50261-50267 Chemical denotes carbon MESH:D002244
1903 50312-50316 Chemical denotes Zn2+
1904 50711-50715 Chemical denotes Zn2+
1905 50800-50804 Chemical denotes Zn2+
1906 50891-50898 Chemical denotes heparin MESH:D006493
1907 51494-51499 Chemical denotes ZnCl2 MESH:C016837
1908 51500-51503 Chemical denotes ZnO MESH:D015034
1909 51504-51520 Chemical denotes hexachloroethane MESH:C010182
1910 48686-48703 Disease denotes blood coagulation MESH:D001778
1911 48789-48812 Disease denotes cardiovascular diseases MESH:D002318
1912 48814-48832 Disease denotes metabolic syndrome MESH:D024821
1913 48834-48846 Disease denotes inflammation MESH:D007249
1914 48860-48866 Disease denotes stress MESH:D000079225
1915 48868-48876 Disease denotes diabetes MESH:D003920
1916 48881-48891 Disease denotes thrombosis MESH:D013927
1917 49008-49027 Disease denotes Alzheimer’s disease MESH:D000544
1918 49032-49051 Disease denotes cardiac dysfunction MESH:D006331
1919 49151-49160 Disease denotes Alzheimer MESH:D000544
1920 49171-49196 Disease denotes neurodegenerative disease MESH:D019636
1921 49466-49474 Disease denotes COVID-19 MESH:C000657245
1922 49695-49700 Disease denotes death MESH:D003643
1923 49722-49748 Disease denotes neurodegenerative diseases MESH:D019636
1924 50353-50365 Disease denotes dyslipidemia MESH:D050171
1925 50465-50471 Disease denotes stress MESH:D000079225
1926 50774-50793 Disease denotes Alzheimer’s disease MESH:D000544
1927 51014-51024 Disease denotes thrombotic MESH:D013927
1928 51335-51338 Disease denotes IBD MESH:D015212
1929 51340-51344 Disease denotes ARDS MESH:D012128
1930 51349-51357 Disease denotes COVID-19 MESH:C000657245
1931 51449-51453 Disease denotes ARDS MESH:D012128
1932 51700-51704 Disease denotes ARDS MESH:D012128
1933 51799-51803 Disease denotes ARDS MESH:D012128
1934 51818-51823 Disease denotes death MESH:D003643
1935 51829-51847 Disease denotes multiorgan failure MESH:D009102
1936 51875-51890 Disease denotes hepatic failure MESH:D017093
1937 52102-52107 Disease denotes death MESH:D003643
1938 52119-52138 Disease denotes respiratory failure MESH:D012131
1939 52372-52400 Disease denotes acute pulmonary hypertension MESH:D006976
1940 52447-52455 Disease denotes fibrosis MESH:D005355
1941 52544-52552 Disease denotes coughing MESH:D003371
1942 52557-52564 Disease denotes dyspnea MESH:D004417
1943 52760-52768 Disease denotes COVID-19 MESH:C000657245
1946 52835-52839 Gene denotes ACE2 Gene:59272
1947 52817-52824 Chemical denotes MLN4760 MESH:C486469
1977 52892-52896 Gene denotes ACE2 Gene:59272
1978 53086-53090 Gene denotes ACE2 Gene:59272
1979 53389-53393 Gene denotes ACE2 Gene:59272
1980 53515-53519 Gene denotes ACE2 Gene:59272
1981 53755-53759 Gene denotes ACE2 Gene:59272
1982 53809-53813 Gene denotes ACE2 Gene:59272
1983 53840-53844 Gene denotes ACE2 Gene:59272
1984 53873-53877 Gene denotes ACE2 Gene:59272
1985 53969-53973 Gene denotes ACE2 Gene:59272
1986 54071-54075 Gene denotes ACE2 Gene:59272
1987 54133-54137 Gene denotes ACE2 Gene:59272
1988 54216-54220 Gene denotes ACE2 Gene:59272
1989 54251-54255 Gene denotes ACE2 Gene:59272
1990 54269-54273 Gene denotes ACE2 Gene:59272
1991 54327-54331 Gene denotes ACE2 Gene:59272
1992 54430-54434 Gene denotes ACE2 Gene:59272
1993 54649-54653 Gene denotes ACE2 Gene:59272
1994 54738-54742 Gene denotes ACE2 Gene:59272
1995 54285-54290 Gene denotes spike Gene:43740568
1996 54110-54115 Gene denotes spike Gene:43740568
1997 54017-54022 Gene denotes spike Gene:43740568
1998 53943-53948 Gene denotes spike Gene:43740568
1999 53834-53839 Gene denotes spike Gene:43740568
2000 54674-54677 Gene denotes MLN Gene:4295
2001 53749-53754 Species denotes human Tax:9606
2002 53867-53872 Species denotes human Tax:9606
2003 54813-54818 Gene denotes spike Gene:43740568
2004 54567-54572 Gene denotes spike Gene:43740568
2005 54798-54803 Chemical denotes sACE2
2046 54874-54878 Gene denotes ACE2 Gene:59272
2047 54927-54931 Gene denotes ACE2 Gene:59272
2048 55273-55276 Gene denotes ACE Gene:59272
2049 55812-55816 Gene denotes ACE2 Gene:59272
2050 56010-56014 Gene denotes CD34 Gene:947
2051 56058-56062 Gene denotes ACE2 Gene:59272
2052 56980-56984 Gene denotes ACE2 Gene:59272
2053 57156-57160 Gene denotes ACE2 Gene:59272
2054 57210-57214 Gene denotes ACE2 Gene:59272
2055 57263-57267 Gene denotes ACE2 Gene:59272
2056 57342-57346 Gene denotes ACE2 Gene:59272
2057 56691-56699 Gene denotes Ang (1–7 Gene:284
2058 56528-56531 Gene denotes MLN Gene:4295
2059 56205-56208 Gene denotes MLN Gene:4295
2060 55153-55156 Gene denotes MLN Gene:4295
2061 55945-55950 Gene denotes mACE2 Gene:70008
2062 55831-55836 Gene denotes mACE2 Gene:70008
2063 54868-54873 Species denotes human Tax:9606
2064 54921-54926 Species denotes human Tax:9606
2065 55263-55268 Species denotes human Tax:9606
2066 57288-57293 Species denotes human Tax:9606
2067 56667-56673 Gene denotes Ang II Gene:24179
2068 54834-54841 Chemical denotes MLN4760 MESH:C486469
2069 55280-55286 Chemical denotes rhACE2
2070 55385-55390 Chemical denotes rhACE
2071 55477-55482 Chemical denotes rhACE
2072 55546-55552 Chemical denotes rhACE2
2073 55622-55628 Chemical denotes rhACE2
2074 55655-55661 Chemical denotes rhACE2
2075 55669-55674 Chemical denotes rhACE
2076 56074-56079 Chemical denotes Dx600
2077 56218-56223 Chemical denotes DX600
2078 56270-56279 Chemical denotes disulfide MESH:D004220
2079 56394-56400 Chemical denotes rhACE2
2080 56589-56595 Chemical denotes rhACE2
2081 56653-56659 Chemical denotes rhACE2
2082 56710-56715 Chemical denotes DX600
2083 56759-56765 Chemical denotes rhACE2
2084 57003-57008 Chemical denotes Dx600
2085 56478-56498 Disease denotes hypercapnic acidosis MESH:D000138
2117 57409-57413 Gene denotes ACE2 Gene:59272
2118 57582-57586 Gene denotes ACE2 Gene:59272
2119 57678-57682 Gene denotes ACE2 Gene:59272
2120 57789-57796 Gene denotes Ang 1–7 Gene:284
2121 57847-57851 Gene denotes ACE2 Gene:70008
2122 58224-58228 Gene denotes ACE2 Gene:302668
2123 58498-58502 Gene denotes ACE2 Gene:302668
2124 58585-58589 Gene denotes ACE2 Gene:70008
2125 58623-58626 Gene denotes ACE Gene:70008
2126 57762-57768 Gene denotes Ang II Gene:24179
2127 58595-58598 Gene denotes MLN Gene:69563
2128 57922-57925 Gene denotes MLN Gene:69563
2129 57492-57495 Gene denotes MLN Gene:4295
2130 57370-57373 Gene denotes MLN Gene:4295
2131 58039-58043 Species denotes mice Tax:10090
2132 58096-58100 Species denotes rats Tax:10116
2133 58470-58474 Species denotes rats Tax:10116
2134 58697-58701 Species denotes mice Tax:10090
2135 58072-58082 Species denotes transgenic Tax:10090
2136 58020-58025 Chemical denotes water MESH:D014867
2137 58375-58382 Chemical denotes MLN4760 MESH:C486469
2138 58665-58679 Chemical denotes streptozotocin MESH:D013311
2139 57885-57897 Disease denotes hypertensive MESH:D006973
2140 58083-58095 Disease denotes hypertensive MESH:D006973
2141 58190-58202 Disease denotes hypertensive MESH:D006973
2142 58308-58320 Disease denotes hypertensive MESH:D006973
2143 58527-58538 Disease denotes bradycardia MESH:D001919
2144 58628-58639 Disease denotes albuminuria MESH:D000419
2145 58644-58661 Disease denotes glomerular injury MESH:D007674
2146 58688-58696 Disease denotes diabetic MESH:D003920
2147 58762-58770 Disease denotes diabetic MESH:D003920
2177 58867-58871 Gene denotes ACE2 Gene:59272
2178 59325-59330 Gene denotes rACE2 Gene:302668
2179 59388-59392 Gene denotes ACE2 Gene:59272
2180 60112-60116 Gene denotes ACE2 Gene:302668
2181 60306-60310 Gene denotes ACE2 Gene:302668
2182 60398-60402 Gene denotes ACE2 Gene:302668
2183 60623-60626 Gene denotes ACE Gene:70008
2184 60627-60631 Gene denotes ACE2 Gene:70008
2185 60475-60478 Gene denotes MLN Gene:69563
2186 60170-60173 Gene denotes MLN Gene:100126231
2187 59760-59763 Gene denotes MLN Gene:100126231
2188 59593-59596 Gene denotes MLN Gene:4295
2189 59275-59278 Gene denotes MLN Gene:69563
2190 59034-59038 Species denotes mice Tax:10090
2191 59168-59173 Species denotes mouse Tax:10090
2192 59319-59324 Species denotes human Tax:9606
2193 59566-59571 Species denotes human Tax:9606
2194 59722-59741 Species denotes Sprague-Dawley rats Tax:10116
2195 60538-60543 Species denotes mouse Tax:10090
2196 58841-58846 Chemical denotes DX600
2197 59875-59880 Chemical denotes water MESH:D014867
2198 60455-60461 Chemical denotes GL1001 MESH:C486469
2199 59201-59218 Disease denotes lung inflammation MESH:D011014
2200 59449-59458 Disease denotes mortality MESH:D003643
2201 59688-59709 Disease denotes myocardial infarction MESH:D009203
2202 59950-59959 Disease denotes pressures MESH:D006973
2203 60136-60157 Disease denotes myocardial infarction MESH:D009203
2204 60209-60217 Disease denotes COVID-19 MESH:C000657245
2205 60553-60560 Disease denotes colitis MESH:D003092
2229 60731-60735 Gene denotes ACE2 Gene:59272
2230 60795-60799 Gene denotes ACE2 Gene:59272
2231 60805-60808 Gene denotes ACE Gene:59272
2232 60924-60928 Gene denotes ACE2 Gene:59272
2233 60934-60937 Gene denotes ACE Gene:59272
2234 61018-61022 Gene denotes ACE2 Gene:59272
2235 61320-61331 Gene denotes transferrin Gene:7018
2236 62165-62172 Species denotes patient Tax:9606
2237 60956-60960 Chemical denotes EDTA MESH:D004492
2238 61051-61055 Chemical denotes EDTA MESH:D004492
2239 61104-61108 Chemical denotes Zn2+
2240 61117-61121 Chemical denotes Ca2+ MESH:D000069285
2241 61126-61130 Chemical denotes Fe2+
2242 61172-61176 Chemical denotes Ca2+ MESH:D000069285
2243 61252-61256 Chemical denotes Zn2+
2244 61293-61297 Chemical denotes iron MESH:D007501
2245 61355-61359 Chemical denotes iron MESH:D007501
2246 61466-61471 Chemical denotes metal MESH:D008670
2247 61528-61532 Chemical denotes EDTA MESH:D004492
2248 61546-61550 Chemical denotes Zn2+
2249 61638-61647 Chemical denotes CaNa2EDTA
2250 62119-62128 Chemical denotes CaNa2EDTA
2251 61934-61949 Disease denotes zinc deficiency MESH:C564286
2267 62686-62689 Gene denotes ACE Gene:59272
2268 62693-62697 Gene denotes ACE2 Gene:59272
2269 62833-62836 Gene denotes ACE Gene:59272
2270 62841-62845 Gene denotes ACE2 Gene:59272
2271 62905-62908 Gene denotes ACE Gene:59272
2272 62913-62917 Gene denotes ACE2 Gene:59272
2273 63140-63144 Gene denotes ACE2 Gene:59272
2274 63145-63148 Gene denotes ACE Gene:59272
2275 63249-63253 Gene denotes ACE2 Gene:59272
2276 63488-63492 Gene denotes ACE2 Gene:59272
2277 63459-63462 Gene denotes MLN Gene:4295
2278 62277-62286 Chemical denotes CaNa2EDTA
2279 62424-62428 Chemical denotes iron MESH:D007501
2280 62612-62617 Chemical denotes metal MESH:D008670
2281 63037-63042 Chemical denotes metal MESH:D008670
2295 63832-63842 Gene denotes fibrinogen Gene:2244
2296 63706-63714 Species denotes patients Tax:9606
2297 64295-64303 Species denotes patients Tax:9606
2298 63529-63540 Chemical denotes chloroquine MESH:D002738
2299 63789-63793 Chemical denotes Zn2+
2300 63868-63879 Chemical denotes chloroquine MESH:D002738
2301 64028-64032 Chemical denotes Zn2+
2302 64208-64212 Chemical denotes Zn2+
2303 64340-64351 Chemical denotes chloroquine MESH:D002738
2304 63697-63705 Disease denotes COVID-19 MESH:C000657245
2305 63911-63921 Disease denotes thrombotic MESH:D013927
2306 64257-64267 Disease denotes thrombotic MESH:D013927
2307 64286-64294 Disease denotes COVID-19 MESH:C000657245
2329 65331-65338 Species denotes patient Tax:9606
2330 64673-64678 Chemical denotes metal MESH:D008670
2331 65098-65102 Chemical denotes EDTA MESH:D004492
2332 65294-65299 Chemical denotes metal MESH:D008670
2333 64497-64505 Disease denotes COVID-19 MESH:C000657245
2334 64506-64515 Disease denotes infection MESH:D007239
2335 64548-64555 Disease denotes hypoxia MESH:D000860
2336 64757-64789 Disease denotes fatal renal toxicity and failure MESH:D051437
2337 64791-64819 Disease denotes hepatic toxicity and failure MESH:D056486
2338 64821-64849 Disease denotes gastrointestinal haemorrhage MESH:D006471
2339 64851-64862 Disease denotes arrhythmias MESH:D001145
2340 64864-64870 Disease denotes tetany MESH:D013746
2341 64872-64885 Disease denotes hypocalcaemia
2342 64887-64898 Disease denotes hypotension MESH:D007022
2343 64900-64911 Disease denotes convulsions MESH:D012640
2344 64913-64931 Disease denotes respiratory arrest MESH:D012131
2345 64937-64952 Disease denotes agranulocytosis MESH:D000380
2346 64978-64988 Disease denotes infections MESH:D007239
2347 64993-64998 Disease denotes death MESH:D003643
2348 65044-65058 Disease denotes renal toxicity MESH:D007674
2349 65145-65166 Disease denotes renal artery diseases MESH:D007674
2388 65654-65658 Gene denotes ACE2 Gene:59272
2389 65671-65674 Gene denotes ACE Gene:59272
2390 65836-65840 Gene denotes ACE2 Gene:59272
2391 65951-65955 Gene denotes ACE2 Gene:59272
2392 66211-66215 Gene denotes ACE2 Gene:59272
2393 66234-66237 Gene denotes ACE Gene:59272
2394 66253-66257 Gene denotes ACE2 Gene:59272
2395 66302-66305 Gene denotes ACE Gene:59272
2396 66310-66314 Gene denotes ACE2 Gene:59272
2397 66383-66387 Gene denotes ACE2 Gene:59272
2398 66423-66426 Gene denotes ACE Gene:59272
2399 66587-66591 Gene denotes ACE2 Gene:59272
2400 66640-66644 Gene denotes ACE2 Gene:59272
2401 66743-66747 Gene denotes ACE2 Gene:59272
2402 66863-66867 Gene denotes ACE2 Gene:59272
2403 66891-66895 Gene denotes ACE2 Gene:59272
2404 67020-67024 Gene denotes ACE2 Gene:59272
2405 67147-67151 Gene denotes ACE2 Gene:59272
2406 67492-67500 Gene denotes Ang (1–9 Gene:284
2407 67544-67548 Gene denotes ACE2 Gene:59272
2408 67483-67487 Gene denotes MasR Gene:116511
2409 67473-67481 Gene denotes Ang (1–7 Gene:284
2410 66915-66920 Gene denotes spike Gene:43740568
2411 67093-67096 Gene denotes MLN Gene:4295
2412 66932-66940 Species denotes SARS-CoV Tax:694009
2413 66826-66834 Species denotes SARS-CoV Tax:694009
2414 66501-66517 Chemical denotes basic amino acid MESH:D024361
2415 66657-66665 Chemical denotes agmatine MESH:D000376
2416 66682-66690 Chemical denotes arginine MESH:D001120
2417 66759-66763 Chemical denotes NAAE
2418 66771-66775 Chemical denotes NAAE
2419 66963-66967 Chemical denotes NAAE
2420 67005-67009 Chemical denotes NAAE
2421 67115-67123 Chemical denotes agmatine MESH:D000376
2422 67583-67591 Chemical denotes agmatine MESH:D000376
2423 67680-67688 Chemical denotes agmatine MESH:D000376
2424 67775-67791 Chemical denotes agmatine sulfate
2425 67741-67757 Disease denotes neuropathic pain MESH:D009437
2442 68289-68293 Gene denotes ACE2 Gene:59272
2443 68298-68301 Gene denotes ACE Gene:59272
2444 68108-68115 Species denotes soybean Tax:3847
2445 68777-68782 Species denotes human Tax:9606
2446 68950-68955 Species denotes human Tax:9606
2447 67855-67860 Chemical denotes metal MESH:D008670
2448 67879-67887 Chemical denotes phytates MESH:D010833
2449 67892-67902 Chemical denotes folic acid MESH:D005492
2450 68063-68076 Chemical denotes nicotianamine MESH:C082893
2451 68143-68148 Chemical denotes metal MESH:D008670
2452 68190-68195 Chemical denotes metal MESH:D008670
2453 68205-68218 Chemical denotes Nicotianamine MESH:C082893
2454 68322-68330 Chemical denotes zeolites MESH:D017641
2455 68415-68430 Chemical denotes aluminosilicate MESH:C049037
2456 68646-68651 Chemical denotes water MESH:D014867
2457 68816-68830 Chemical denotes clinoptilolite MESH:C083175
2473 69033-69037 Gene denotes ACE2 Gene:59272
2474 69244-69248 Gene denotes ACE2 Gene:59272
2475 69351-69355 Gene denotes ACE2 Gene:59272
2476 69490-69494 Gene denotes ACE2 Gene:59272
2477 69618-69623 Gene denotes hACE2 Gene:59272
2478 69201-69211 Species denotes SARS-CoV-2 Tax:2697049
2479 69345-69350 Species denotes human Tax:9606
2480 69711-69719 Species denotes patients Tax:9606
2481 69749-69755 Chemical denotes rhACE2
2482 69081-69099 Disease denotes SARS-CoV infection MESH:C000657245
2483 69278-69293 Disease denotes viral infection MESH:D001102
2484 69386-69394 Disease denotes COVID-19 MESH:C000657245
2485 69408-69412 Disease denotes ARDS MESH:D012128
2486 69702-69710 Disease denotes COVID-19 MESH:C000657245
2487 69759-69763 Disease denotes ARDS MESH:D012128
2490 69922-69926 Gene denotes ACE2 Gene:59272
2491 69987-69995 Disease denotes COVID-19 MESH:C000657245
2562 70997-71001 Gene denotes ACE2 Gene:59272
2563 71181-71184 Gene denotes ACE Gene:59272
2564 71311-71315 Gene denotes ACE2 Gene:59272
2565 71550-71554 Gene denotes ACE2 Gene:59272
2566 71674-71678 Gene denotes ACE2 Gene:302668
2567 71764-71772 Gene denotes Ang (1–7 Gene:305843
2568 71953-71956 Gene denotes ACE Gene:302668
2569 72007-72011 Gene denotes ACE2 Gene:302668
2570 72022-72026 Gene denotes MasR Gene:116511
2571 72174-72178 Gene denotes ACE2 Gene:59272
2572 72306-72310 Gene denotes ACE2 Gene:59272
2573 72481-72484 Gene denotes AT1 Gene:185
2574 72494-72498 Gene denotes ACE2 Gene:59272
2575 72609-72613 Gene denotes ACE2 Gene:59272
2576 72712-72716 Gene denotes ACE2 Gene:59272
2577 74331-74335 Gene denotes ACE2 Gene:59272
2578 74347-74353 Gene denotes Ang II Gene:24179
2579 74395-74403 Gene denotes Ang (1–9 Gene:284
2580 74522-74526 Gene denotes ACE2 Gene:59272
2581 74527-74530 Gene denotes ACE Gene:59272
2582 74376-74384 Gene denotes Ang (1–7 Gene:284
2583 72012-72020 Gene denotes Ang (1–7 Gene:305843
2584 70641-70649 Species denotes patients Tax:9606
2585 71149-71157 Species denotes patients Tax:9606
2586 71449-71457 Species denotes patients Tax:9606
2587 71715-71719 Species denotes rats Tax:10116
2588 71856-71860 Species denotes rats Tax:10116
2589 71926-71930 Species denotes rats Tax:10116
2590 72072-72078 Species denotes humans Tax:9606
2591 72333-72338 Species denotes human Tax:9606
2592 72967-72975 Species denotes patients Tax:9606
2593 73168-73176 Species denotes patients Tax:9606
2594 73472-73480 Species denotes patients Tax:9606
2595 73528-73536 Species denotes patients Tax:9606
2596 73888-73896 Species denotes patients Tax:9606
2597 74027-74035 Species denotes patients Tax:9606
2598 74228-74236 Species denotes patients Tax:9606
2599 74288-74296 Species denotes patients Tax:9606
2600 72452-72458 Gene denotes Ang II Gene:24179
2601 70447-70454 Chemical denotes calcium MESH:D002118
2602 71490-71505 Chemical denotes cholecalciferol MESH:D002762
2603 71602-71610 Chemical denotes losartan MESH:D019808
2604 71629-71639 Chemical denotes lisinopril MESH:D017706
2605 73822-73830 Chemical denotes losartan MESH:D019808
2606 70015-70023 Disease denotes COVID-19 MESH:C000657245
2607 70075-70087 Disease denotes hypertension MESH:D006973
2608 70089-70097 Disease denotes diabetes MESH:D003920
2609 70197-70209 Disease denotes hypertensive MESH:D006973
2610 70236-70248 Disease denotes hypertensive MESH:D006973
2611 70331-70343 Disease denotes hypertension MESH:D006973
2612 70903-70915 Disease denotes hypertension MESH:D006973
2613 70917-70925 Disease denotes diabetes MESH:D003920
2614 70927-70939 Disease denotes dyslipidemia MESH:D050171
2615 71077-71089 Disease denotes hypertensive MESH:D006973
2616 71126-71134 Disease denotes COVID-19 MESH:C000657245
2617 71140-71148 Disease denotes diabetic MESH:D003920
2618 72222-72240 Disease denotes hypoxic conditions MESH:D000071069
2619 72631-72649 Disease denotes hypoxic conditions MESH:D000071069
2620 72658-72666 Disease denotes COVID-19 MESH:C000657245
2621 72981-72989 Disease denotes COVID-19 MESH:C000657245
2622 73084-73092 Disease denotes COVID-19 MESH:C000657245
2623 73204-73212 Disease denotes COVID-19 MESH:C000657245
2624 73271-73280 Disease denotes mortality MESH:D003643
2625 73432-73440 Disease denotes COVID-19 MESH:C000657245
2626 73652-73657 Disease denotes death MESH:D003643
2627 73850-73858 Disease denotes COVID-19 MESH:C000657245
2628 74005-74017 Disease denotes hypertensive MESH:D006973
2629 74018-74026 Disease denotes diabetic MESH:D003920
2630 74215-74227 Disease denotes hypertensive MESH:D006973
2631 74279-74287 Disease denotes COVID-19 MESH:C000657245
2728 74707-74711 Gene denotes ACE2 Gene:59272
2729 74792-74796 Gene denotes ACE2 Gene:59272
2730 75220-75224 Gene denotes ACE2 Gene:302668
2731 75402-75406 Gene denotes ACE2 Gene:59272
2732 75582-75586 Gene denotes ACE2 Gene:59272
2733 75813-75817 Gene denotes ACE2 Gene:59272
2734 76062-76066 Gene denotes ACE2 Gene:59272
2735 76149-76153 Gene denotes ACE2 Gene:59272
2736 76280-76284 Gene denotes ACE2 Gene:59272
2737 76342-76346 Gene denotes ACE2 Gene:59272
2738 76859-76863 Gene denotes ACE2 Gene:59272
2739 77560-77564 Gene denotes ACE2 Gene:59272
2740 77580-77583 Gene denotes ACE Gene:59272
2741 77584-77588 Gene denotes ACE2 Gene:59272
2742 77943-77947 Gene denotes ACE2 Gene:59272
2743 77981-77985 Gene denotes ACE2 Gene:59272
2744 78115-78119 Gene denotes ACE2 Gene:59272
2745 78507-78511 Gene denotes ACE2 Gene:59272
2746 79153-79157 Gene denotes ACE2 Gene:59272
2747 74632-74639 Gene denotes insulin Gene:3630
2748 74873-74876 Species denotes men Tax:9606
2749 74978-74982 Species denotes rats Tax:10116
2750 75301-75309 Species denotes patients Tax:9606
2751 75484-75492 Species denotes patients Tax:9606
2752 76568-76576 Species denotes patients Tax:9606
2753 76757-76765 Species denotes patients Tax:9606
2754 77049-77057 Species denotes patients Tax:9606
2755 77358-77366 Species denotes patients Tax:9606
2756 77415-77423 Species denotes patients Tax:9606
2757 77799-77809 Species denotes SARS-CoV-2 Tax:2697049
2758 78733-78741 Species denotes patients Tax:9606
2759 79335-79343 Species denotes patients Tax:9606
2760 80135-80148 Species denotes coronaviruses Tax:11118
2761 80239-80249 Species denotes SARS-CoV-2 Tax:2697049
2762 80322-80337 Species denotes influenza virus Tax:11308
2763 80400-80406 Species denotes humans Tax:9606
2764 80440-80453 Species denotes coronaviruses Tax:11118
2765 80646-80654 Species denotes SARS-CoV Tax:694009
2766 80659-80667 Species denotes MERS-CoV Tax:1335626
2767 81052-81062 Species denotes SARS-CoV-2 Tax:2697049
2768 76688-76693 Chemical denotes sACE2
2769 76701-76705 Chemical denotes Zn2+
2770 77230-77234 Chemical denotes Zn2+
2771 77478-77488 Chemical denotes olmesartan MESH:C437965
2772 74942-74954 Disease denotes hypertensive MESH:D006973
2773 75063-75069 Disease denotes asthma MESH:D001249
2774 75080-75097 Disease denotes allergic diseases MESH:D004342
2775 75129-75137 Disease denotes COVID-19 MESH:C000657245
2776 75315-75338 Disease denotes cardiovascular diseases MESH:D002318
2777 75344-75370 Disease denotes inflammatory bowel disease MESH:D015212
2778 75504-75512 Disease denotes COVID-19 MESH:C000657245
2779 75544-75563 Disease denotes atrial fibrillation MESH:D001281
2780 75639-75658 Disease denotes cardiac dysfunction MESH:D006331
2781 75692-75704 Disease denotes hypertension MESH:D006973
2782 75720-75736 Disease denotes vascular disease MESH:D000783
2783 75889-75897 Disease denotes COVID-19 MESH:C000657245
2784 76095-76110 Disease denotes viral infection MESH:D001102
2785 76317-76325 Disease denotes COVID-19 MESH:C000657245
2786 76416-76424 Disease denotes COVID-19 MESH:C000657245
2787 76521-76542 Disease denotes chronic renal disease MESH:D051436
2788 76546-76554 Disease denotes COVID-19 MESH:C000657245
2789 76734-76756 Disease denotes chronic kidney disease MESH:D051436
2790 76787-76809 Disease denotes cardiovascular disease MESH:D002318
2791 76948-76959 Disease denotes proteinuria MESH:D011507
2792 77026-77048 Disease denotes chronic kidney disease MESH:D051436
2793 77142-77164 Disease denotes chronic renal diseases MESH:D051436
2794 77372-77394 Disease denotes chronic renal diseases MESH:D051436
2795 77402-77414 Disease denotes hypertensive MESH:D006973
2796 77543-77556 Disease denotes hyperactivity MESH:D006948
2797 77672-77680 Disease denotes COVID-19 MESH:C000657245
2798 77778-77788 Disease denotes infections MESH:D007239
2799 77889-77909 Disease denotes SARS-CoV-2 infection MESH:C000657245
2800 78169-78181 Disease denotes hypertension MESH:D006973
2801 78183-78195 Disease denotes dyslipidemia MESH:D050171
2802 78204-78212 Disease denotes diabetes MESH:D003920
2803 78217-78243 Disease denotes cardiovascular dysfunction MESH:D002318
2804 78543-78551 Disease denotes COVID-19 MESH:C000657245
2805 78580-78603 Disease denotes obstructive sleep apnea MESH:D020181
2806 78661-78669 Disease denotes COVID-19 MESH:C000657245
2807 78724-78732 Disease denotes COVID-19 MESH:C000657245
2808 78834-78842 Disease denotes Covid-19 MESH:C000657245
2809 78900-78914 Disease denotes apnea/hypopnea MESH:D020181
2810 78932-78942 Disease denotes hypoxaemia
2811 78950-78955 Disease denotes sleep MESH:D012893
2812 78982-78994 Disease denotes hypertension MESH:D006973
2813 78996-79018 Disease denotes cardiovascular disease MESH:D002318
2814 79020-79028 Disease denotes diabetes MESH:D003920
2815 79030-79037 Disease denotes obesity MESH:D009765
2816 79051-79063 Disease denotes inflammation MESH:D007249
2817 79185-79192 Disease denotes hypoxia MESH:D000860
2818 79306-79326 Disease denotes SARS-CoV-2 infection MESH:C000657245
2819 79646-79651 Disease denotes sleep MESH:D012893
2820 79779-79787 Disease denotes COVID-19 MESH:C000657245
2821 80385-80396 Disease denotes common cold MESH:D003139
2822 80704-80724 Disease denotes SARS-CoV-2 infection MESH:C000657245
2823 81024-81040 Disease denotes virus infections MESH:D001102
2827 81335-81338 Gene denotes ACE Gene:59272
2828 81339-81343 Gene denotes ACE2 Gene:59272
2829 81356-81364 Disease denotes COVID-19 MESH:C000657245
2872 82422-82426 Gene denotes ACE2 Gene:59272
2873 82455-82459 Gene denotes ACE2 Gene:59272
2874 82689-82693 Gene denotes IL-4 Gene:3565
2875 82695-82699 Gene denotes IL-5 Gene:3567
2876 82704-82709 Gene denotes IL-10 Gene:3586
2877 82743-82746 Gene denotes Th2 Gene:15111
2878 82903-82908 Gene denotes IL-10 Gene:3586
2879 83193-83197 Gene denotes ACE2 Gene:59272
2880 83277-83281 Gene denotes ACE2 Gene:59272
2881 83306-83311 Gene denotes IL-10 Gene:3586
2882 83420-83425 Gene denotes renin Gene:5972
2883 83426-83429 Gene denotes ACE Gene:59272
2884 83537-83541 Gene denotes IL-6 Gene:3569
2885 82793-82796 Gene denotes CD4 Gene:920
2886 82658-82661 Gene denotes Th2 Gene:15111
2887 81597-81605 Species denotes patients Tax:9606
2888 81612-81622 Species denotes SARS-CoV-2 Tax:2697049
2889 81737-81745 Species denotes patients Tax:9606
2890 82009-82019 Species denotes SARS-CoV-2 Tax:2697049
2891 82091-82101 Species denotes SARS-CoV-2 Tax:2697049
2892 82158-82166 Species denotes SARS-CoV Tax:694009
2893 82264-82272 Species denotes SARS-CoV Tax:694009
2894 83012-83020 Species denotes patients Tax:9606
2895 83103-83113 Species denotes SARS-CoV-2 Tax:2697049
2896 83114-83122 Species denotes patients Tax:9606
2897 81491-81511 Disease denotes SARS-CoV-2 infection MESH:C000657245
2898 81588-81596 Disease denotes COVID-19 MESH:C000657245
2899 81728-81736 Disease denotes COVID-19 MESH:C000657245
2900 82196-82202 Disease denotes asthma MESH:D001249
2901 82476-82494 Disease denotes SARS-CoV infection MESH:C000657245
2902 82521-82527 Disease denotes asthma MESH:D001249
2903 82587-82605 Disease denotes SARS-CoV infection MESH:C000657245
2904 82845-82854 Disease denotes infection MESH:D007239
2905 82911-82923 Disease denotes eosinopaenia
2906 82925-82936 Disease denotes tachycardia MESH:D013610
2907 82944-82955 Disease denotes hypotension MESH:D007022
2908 82966-82974 Disease denotes COVID-19 MESH:C000657245
2909 82979-83002 Disease denotes hypoxia increase Ang II MESH:D000860
2910 83026-83038 Disease denotes hypertensive MESH:D006973
2911 83062-83074 Disease denotes hypertensive MESH:D006973
2912 83092-83099 Disease denotes hypoxia MESH:D000860
2913 83568-83576 Disease denotes COVID-19 MESH:C000657245
2916 83640-83644 Gene denotes ACE2 Gene:59272
2917 83871-83889 Disease denotes multi-organ injury MESH:D009102
2923 84455-84459 Gene denotes ACE2 Gene:59272
2924 84597-84601 Gene denotes ACE2 Gene:59272
2925 84403-84413 Species denotes SARS-CoV-2 Tax:2697049
2926 84815-84823 Species denotes patients Tax:9606
2927 84806-84814 Disease denotes COVID-19 MESH:C000657245
2934 84884-84887 Gene denotes ACE Gene:59272
2935 84888-84892 Gene denotes ACE2 Gene:59272
2936 85026-85030 Gene denotes ACE2 Gene:59272
2937 85112-85115 Gene denotes ACE Gene:59272
2938 85116-85120 Gene denotes ACE2 Gene:59272
2939 85081-85086 Chemical denotes ZnCl2 MESH:C016837
2942 85238-85241 Gene denotes ACE Gene:59272
2943 85242-85246 Gene denotes ACE2 Gene:59272
2947 85349-85353 Gene denotes AT1R Gene:185
2948 85355-85359 Gene denotes AT2R Gene:24182
2949 85364-85368 Gene denotes MasR Gene:116511
2952 85175-85178 Gene denotes ACE Gene:59272
2953 85179-85183 Gene denotes ACE2 Gene:59272
2965 83949-83952 Gene denotes ACE Gene:59272
2966 83953-83957 Gene denotes ACE2 Gene:59272
2967 83997-84000 Gene denotes ACE Gene:59272
2968 84005-84009 Gene denotes ACE2 Gene:59272
2969 84047-84054 Gene denotes Ang 1–9 Gene:284
2970 84078-84086 Gene denotes Ang (1–5 Gene:284
2971 84139-84149 Gene denotes bradykinin Gene:3827
2972 84100-84110 Gene denotes bradykinin Gene:3827
2973 84064-84072 Gene denotes Ang (1–7 Gene:27329
2974 84056-84062 Gene denotes Ang II Gene:24179
2975 84089-84096 Chemical denotes des-Arg
2984 85479-85483 Gene denotes ACE2 Gene:59272
2985 85602-85606 Gene denotes MasR Gene:116511
2986 85716-85726 Gene denotes bradykinin Gene:3827
2987 85866-85870 Gene denotes ACE2 Gene:59272
2988 85443-85451 Gene denotes Ang (1–7 Gene:284
2989 85746-85754 Species denotes patients Tax:9606
2990 85561-85567 Gene denotes Ang II Gene:24179
2991 85737-85745 Disease denotes COVID-19 MESH:C000657245
3005 85960-85965 Gene denotes rACE2 Gene:302668
3006 86079-86083 Gene denotes ACE2 Gene:59272
3007 86242-86250 Gene denotes Ang (1–9 Gene:284
3008 86253-86261 Gene denotes Ang (1–7 Gene:284
3009 86268-86271 Gene denotes ACE Gene:59272
3010 86310-86318 Gene denotes Ang (1–5 Gene:284
3011 86367-86370 Gene denotes ACE Gene:59272
3012 86371-86375 Gene denotes ACE2 Gene:59272
3013 86138-86144 Gene denotes Ang II Gene:24179
3014 86282-86290 Gene denotes Ang (1–5 Gene:284
3015 85954-85959 Species denotes human Tax:9606
3016 86406-86414 Species denotes patients Tax:9606
3017 86397-86405 Disease denotes COVID-19 MESH:C000657245
3033 86486-86492 Gene denotes Ang II Gene:24179
3034 86764-86772 Gene denotes Ang (1–7 Gene:284
3035 86775-86783 Gene denotes Ang (1–9 Gene:284
3036 86786-86794 Gene denotes Ang (1–5 Gene:284
3037 86800-86810 Gene denotes bradykinin Gene:3827
3038 86516-86524 Species denotes patients Tax:9606
3039 86933-86941 Species denotes patients Tax:9606
3040 86496-86515 Disease denotes SARS-CoV-2 infected MESH:C000657245
3041 86698-86709 Disease denotes lung injury MESH:D055370
3042 86892-86903 Disease denotes hypotension MESH:D007022
3043 86908-86920 Disease denotes eosinopaenia
3044 86924-86932 Disease denotes COVID-19 MESH:C000657245
3045 86993-87028 Disease denotes Acute Respiratory distress syndrome MESH:D012128
3046 87032-87040 Disease denotes COVID-19 MESH:C000657245
3047 87060-87091 Disease denotes pulmonary arterial hypertension MESH:D000081029
3049 87134-87169 Disease denotes Acute Respiratory distress syndrome MESH:D012128
3076 87525-87528 Gene denotes ACE Gene:59272
3077 87680-87684 Gene denotes ACE2 Gene:59272
3078 87732-87736 Gene denotes AT1R Gene:185
3079 87791-87795 Gene denotes ACE2 Gene:59272
3080 87880-87884 Gene denotes ACE2 Gene:59272
3081 87245-87253 Species denotes patients Tax:9606
3082 87489-87498 Species denotes SARS-CoVs Tax:694009
3083 87502-87507 Species denotes human Tax:9606
3084 87508-87523 Species denotes influenza virus Tax:11308
3085 87598-87604 Species denotes humans Tax:9606
3086 87874-87879 Species denotes human Tax:9606
3087 88121-88129 Species denotes patients Tax:9606
3088 87725-87731 Gene denotes Ang II Gene:24179
3089 87240-87244 Disease denotes ARDS MESH:D012128
3090 87327-87336 Disease denotes hypoxemia MESH:D000860
3091 87338-87342 Disease denotes ARDS MESH:D012128
3092 87404-87410 Disease denotes sepsis MESH:D018805
3093 87412-87418 Disease denotes trauma MESH:D014947
3094 87420-87438 Disease denotes acute pancreatitis MESH:D010195
3095 87443-87453 Disease denotes pneumonias MESH:D011014
3096 87464-87480 Disease denotes virus infections MESH:D001102
3097 87590-87594 Disease denotes ARDS MESH:D012128
3098 87651-87655 Disease denotes ARDS MESH:D012128
3099 87799-87803 Disease denotes ARDS MESH:D012128
3100 87993-87997 Disease denotes ARDS MESH:D012128
3101 88112-88120 Disease denotes COVID-19 MESH:C000657245
3215 88541-88546 Gene denotes renin Gene:5972
3216 89304-89309 Gene denotes renin Gene:5972
3217 89311-89314 Gene denotes ACE Gene:59272
3218 89322-89326 Gene denotes ACE2 Gene:59272
3219 89607-89615 Gene denotes Ang (1–9 Gene:284
3220 89911-89914 Gene denotes ACE Gene:59272
3221 89923-89927 Gene denotes ACE2 Gene:59272
3222 90237-90245 Gene denotes Ang (1–9 Gene:284
3223 90404-90407 Gene denotes ACE Gene:59272
3224 90443-90447 Gene denotes ACE2 Gene:59272
3225 90458-90462 Gene denotes MasR Gene:116511
3226 90880-90886 Gene denotes Ang II Gene:24179
3227 91289-91297 Gene denotes Ang (1–7 Gene:284
3228 91817-91821 Gene denotes ACE2 Gene:59272
3229 91836-91840 Gene denotes ACE2 Gene:59272
3230 92008-92016 Gene denotes Ang (1–9 Gene:284
3231 92070-92074 Gene denotes ACE2 Gene:59272
3232 92100-92103 Gene denotes ACE Gene:59272
3233 92291-92296 Gene denotes rACE2 Gene:302668
3234 92451-92454 Gene denotes ACE Gene:59272
3235 92508-92512 Gene denotes ACE2 Gene:59272
3236 92542-92550 Gene denotes Ang (1–9 Gene:284
3237 92594-92598 Gene denotes ACE2 Gene:59272
3238 92622-92630 Gene denotes Ang (1–9 Gene:284
3239 92664-92672 Gene denotes Ang (1–5 Gene:284
3240 92707-92711 Gene denotes ACE2 Gene:59272
3241 92754-92757 Gene denotes ACE Gene:59272
3242 92791-92799 Gene denotes Ang (1–5 Gene:284
3243 93003-93007 Gene denotes ACE2 Gene:59272
3244 93012-93015 Gene denotes ACE Gene:59272
3245 93303-93308 Gene denotes renin Gene:5972
3246 93380-93388 Gene denotes Ang (1–9 Gene:284
3247 93433-93437 Gene denotes ACE2 Gene:59272
3248 93469-93477 Gene denotes Ang (1–9 Gene:284
3249 93591-93596 Gene denotes rACE2 Gene:302668
3250 93648-93656 Gene denotes Ang (1–9 Gene:284
3251 93670-93678 Gene denotes Ang (1–5 Gene:284
3252 93826-93830 Gene denotes ACE2 Gene:59272
3253 94124-94128 Gene denotes ACE2 Gene:59272
3254 94379-94384 Gene denotes TNF-α Gene:7124
3255 94511-94519 Gene denotes Ang (1–7 Gene:284
3256 94576-94581 Gene denotes hACE2 Gene:59272
3257 94288-94296 Gene denotes Ang (1–7 Gene:284
3258 93684-93692 Gene denotes Ang (1–7 Gene:284
3259 93361-93369 Gene denotes Ang (1–5 Gene:284
3260 93347-93355 Gene denotes Ang (1–7 Gene:284
3261 92818-92826 Gene denotes Ang (1–5 Gene:284
3262 92806-92814 Gene denotes Ang (1–7 Gene:284
3263 92356-92364 Gene denotes Ang (1–9 Gene:284
3264 91718-91726 Gene denotes Ang (1–7 Gene:284
3265 91644-91652 Gene denotes Ang (1–7 Gene:284
3266 91429-91437 Gene denotes Ang (1–7 Gene:284
3267 91145-91153 Gene denotes Ang (1–7 Gene:284
3268 91131-91139 Gene denotes Ang (1–7 Gene:284
3269 90448-90456 Gene denotes Ang (1–7 Gene:284
3270 90251-90259 Gene denotes Ang (1–7 Gene:284
3271 90219-90227 Gene denotes Ang (1–7 Gene:284
3272 90166-90174 Gene denotes Ang (1–7 Gene:284
3273 90058-90066 Gene denotes Ang (1–7 Gene:284
3274 89621-89629 Gene denotes Ang (1–5 Gene:284
3275 89596-89604 Gene denotes Ang (1–7 Gene:284
3276 93161-93166 Gene denotes renin Gene:5972
3277 89901-89906 Gene denotes renin Gene:5972
3278 88316-88324 Species denotes patients Tax:9606
3279 88578-88586 Species denotes patients Tax:9606
3280 88722-88729 Species denotes patient Tax:9606
3281 90329-90337 Species denotes patients Tax:9606
3282 90543-90551 Species denotes patients Tax:9606
3283 91183-91191 Species denotes patients Tax:9606
3284 91905-91913 Species denotes patients Tax:9606
3285 92285-92290 Species denotes human Tax:9606
3286 92319-92327 Species denotes patients Tax:9606
3287 92521-92529 Species denotes patients Tax:9606
3288 92924-92932 Species denotes patients Tax:9606
3289 93529-93537 Species denotes patients Tax:9606
3290 93585-93590 Species denotes human Tax:9606
3291 93734-93742 Species denotes patients Tax:9606
3292 93889-93897 Species denotes patients Tax:9606
3293 94339-94347 Species denotes patients Tax:9606
3294 94589-94597 Species denotes patients Tax:9606
3295 92727-92735 Gene denotes Ang (1–7 Gene:27329
3296 94504-94510 Gene denotes Ang II Gene:24179
3297 94277-94283 Gene denotes Ang II Gene:24179
3298 93339-93345 Gene denotes Ang II Gene:24179
3299 92773-92779 Gene denotes Ang II Gene:24179
3300 92742-92748 Gene denotes Ang II Gene:24179
3301 91728-91734 Gene denotes Ang II Gene:24179
3302 91533-91539 Gene denotes Ang II Gene:24179
3303 91439-91445 Gene denotes Ang II Gene:24179
3304 91375-91381 Gene denotes Ang II Gene:24179
3305 91155-91161 Gene denotes Ang II Gene:24179
3306 90717-90723 Gene denotes Ang II Gene:24179
3307 90261-90267 Gene denotes Ang II Gene:24179
3308 90176-90182 Gene denotes Ang II Gene:24179
3309 90047-90053 Gene denotes Ang II Gene:24179
3310 89588-89594 Gene denotes Ang II Gene:24179
3311 89363-89374 Chemical denotes Ang peptide
3312 88311-88315 Disease denotes ARDS MESH:D012128
3313 88573-88577 Disease denotes ARDS MESH:D012128
3314 88629-88633 Disease denotes ARDS MESH:D012128
3315 90316-90328 Disease denotes hypertensive MESH:D006973
3316 90538-90542 Disease denotes ARDS MESH:D012128
3317 91178-91182 Disease denotes ARDS MESH:D012128
3318 91900-91904 Disease denotes ARDS MESH:D012128
3319 92314-92318 Disease denotes ARDS MESH:D012128
3320 92516-92520 Disease denotes ARDS MESH:D012128
3321 92919-92923 Disease denotes ARDS MESH:D012128
3322 93524-93528 Disease denotes ARDS MESH:D012128
3323 93729-93733 Disease denotes ARDS MESH:D012128
3324 93884-93888 Disease denotes ARDS MESH:D012128
3325 94205-94229 Disease denotes coronary atherosclerosis MESH:D003324
3326 94429-94452 Disease denotes coronary artery disease MESH:D003324
3327 94628-94637 Disease denotes pressures MESH:D006973
3329 94940-94948 Disease denotes COVID-19 MESH:C000657245
3347 95004-95008 Gene denotes ACE2 Gene:59272
3348 95122-95126 Gene denotes ACE2 Gene:59272
3349 95275-95279 Gene denotes ACE2 Gene:59272
3350 95346-95350 Gene denotes ACE2 Gene:59272
3351 95380-95384 Gene denotes ACE2 Gene:59272
3352 95405-95408 Gene denotes ACE Gene:59272
3353 95409-95413 Gene denotes ACE2 Gene:59272
3354 95562-95566 Gene denotes ACE2 Gene:59272
3355 95593-95597 Gene denotes MasR Gene:116511
3356 95617-95622 Gene denotes renin Gene:5972
3357 95361-95365 Gene denotes MasR Gene:116511
3358 95050-95058 Species denotes patients Tax:9606
3359 95232-95242 Species denotes SARS-CoV-2 Tax:2697049
3360 95351-95359 Gene denotes Ang (1–7 Gene:27329
3361 95641-95646 Chemical denotes metal MESH:D008670
3362 95041-95049 Disease denotes COVID-19 MESH:C000657245
3363 95488-95495 Disease denotes hypoxia MESH:D000860
3387 95735-95739 Gene denotes ACE2 Gene:59272
3388 95869-95873 Gene denotes ACE2 Gene:70008
3389 95966-95970 Gene denotes ACE2 Gene:70008
3390 96163-96167 Gene denotes ACE2 Gene:59272
3391 96382-96386 Gene denotes ACE2 Gene:59272
3392 96346-96349 Gene denotes MLN Gene:4295
3393 96190-96193 Gene denotes MLN Gene:4295
3394 95796-95800 Gene denotes MasR Gene:116511
3395 95729-95734 Species denotes human Tax:9606
3396 95790-95795 Species denotes human Tax:9606
3397 95918-95923 Species denotes mouse Tax:10090
3398 95924-95927 Species denotes rat Tax:10116
3399 95950-95955 Species denotes human Tax:9606
3400 95960-95965 Species denotes mouse Tax:10090
3401 95986-95991 Species denotes mouse Tax:10090
3402 96021-96026 Species denotes mouse Tax:10090
3403 96027-96030 Species denotes rat Tax:10116
3404 96081-96086 Species denotes human Tax:9606
3405 96087-96099 Species denotes participants Tax:9606
3406 96157-96162 Species denotes human Tax:9606
3407 96434-96440 Species denotes humans Tax:9606
3408 96002-96009 Disease denotes colitis MESH:D003092
3409 96130-96138 Disease denotes toxicity MESH:D064420
3416 96612-96616 Gene denotes ACE2 Gene:59272
3417 96724-96728 Gene denotes ACE2 Gene:59272
3418 96606-96611 Species denotes human Tax:9606
3419 96711-96716 Species denotes human Tax:9606
3420 96914-96922 Species denotes patients Tax:9606
3421 96902-96910 Disease denotes COVID-19 MESH:C000657245
3424 97067-97071 Gene denotes ACE2 Gene:59272
3425 97073-97076 Gene denotes MLN Gene:4295
3437 97354-97358 Gene denotes ACE2 Gene:59272
3438 97500-97504 Gene denotes ACE2 Gene:59272
3439 97590-97594 Gene denotes ACE2 Gene:59272
3440 97672-97676 Gene denotes ACE2 Gene:59272
3441 97697-97701 Gene denotes ACE2 Gene:59272
3442 97604-97609 Gene denotes spike Gene:43740568
3443 97479-97487 Species denotes patients Tax:9606
3444 97494-97499 Species denotes human Tax:9606
3445 97713-97723 Species denotes SARS-CoV-2 Tax:2697049
3446 97427-97438 Disease denotes hypercapnia MESH:D006935
3447 97470-97478 Disease denotes COVID-19 MESH:C000657245
3451 97874-97878 Gene denotes ACE2 Gene:59272
3452 97978-97982 Gene denotes ACE2 Gene:59272
3453 98082-98088 Species denotes humans Tax:9606
3457 98336-98340 Gene denotes ACE2 Gene:59272
3458 98545-98552 Gene denotes insulin Gene:3630
3459 98446-98451 Chemical denotes water MESH:D014867
3466 98706-98710 Gene denotes ACE2 Gene:59272
3467 98669-98682 Chemical denotes disodium salt
3468 98870-98900 Chemical denotes 2-hydroxypropyl-β-cyclodextrin MESH:D000073738
3469 98902-98907 Chemical denotes HPBDC
3470 98913-98916 Chemical denotes H2O
3471 98945-98951 Chemical denotes GL1001 MESH:C486469
3477 99264-99268 Gene denotes ACE2 Gene:59272
3478 99040-99043 Gene denotes MLN Gene:4295
3479 99018-99024 Species denotes humans Tax:9606
3480 99170-99196 Disease denotes Inflammatory bowel disease MESH:D015212
3481 99198-99219 Disease denotes gastritis and colitis MESH:D005756
3490 100218-100222 Gene denotes ACE2 Gene:59272
3491 100443-100446 Gene denotes MLN Gene:4295
3492 99990-99993 Gene denotes MLN Gene:69563
3493 100091-100095 Species denotes mice Tax:10090
3494 100099-100110 Species denotes Pseudomonas Tax:287
3495 100077-100090 Disease denotes lung-infected MESH:D012141
3496 100238-100255 Disease denotes lung inflammation MESH:D011014
3497 100430-100438 Disease denotes toxicity MESH:D064420
3499 98234-98240 Species denotes humans Tax:9606
3504 97229-97233 Gene denotes ACE2 Gene:59272
3505 97210-97213 Gene denotes MLN Gene:4295
3506 97136-97144 Species denotes patients Tax:9606
3507 97127-97135 Disease denotes COVID-19 MESH:C000657245
3528 100924-100927 Gene denotes ACE Gene:59272
3529 100928-100932 Gene denotes ACE2 Gene:59272
3530 100952-100955 Gene denotes ACE Gene:59272
3531 101014-101018 Gene denotes ACE2 Gene:59272
3532 101698-101702 Gene denotes ACE2 Gene:59272
3533 101863-101867 Gene denotes ACE2 Gene:59272
3534 102108-102112 Gene denotes ACE2 Gene:59272
3535 101506-101509 Gene denotes MLN Gene:4295
3536 101194-101197 Gene denotes MLN Gene:4295
3537 100523-100526 Gene denotes MLN Gene:4295
3538 100707-100715 Species denotes patients Tax:9606
3539 101132-101140 Species denotes patients Tax:9606
3540 101669-101677 Species denotes patients Tax:9606
3541 101928-101936 Species denotes patients Tax:9606
3542 102040-102045 Species denotes human Tax:9606
3543 102149-102157 Species denotes patients Tax:9606
3544 102316-102323 Species denotes patient Tax:9606
3545 100803-100821 Disease denotes hypoxic conditions MESH:D000071069
3546 101123-101131 Disease denotes COVID-19 MESH:C000657245
3547 101919-101927 Disease denotes COVID-19 MESH:C000657245
3549 102355-102360 Gene denotes Renin Gene:5972
3574 102499-102504 Gene denotes renin Gene:5972
3575 103051-103054 Gene denotes ACE Gene:59272
3576 103059-103063 Gene denotes ACE2 Gene:59272
3577 103171-103175 Gene denotes AT1R Gene:24180
3578 103302-103307 Gene denotes renin Gene:24715
3579 103447-103451 Gene denotes AT2R Gene:24182
3580 103456-103460 Gene denotes ACE2 Gene:59272
3581 103180-103184 Gene denotes MasR Gene:116511
3582 103269-103277 Gene denotes Ang (1–7 Gene:305843
3583 102463-102468 Gene denotes renin Gene:5972
3584 102851-102859 Species denotes patients Tax:9606
3585 103132-103136 Species denotes rats Tax:10116
3586 103258-103264 Gene denotes Ang II Gene:24179
3587 102703-102712 Chemical denotes Aliskiren MESH:C446481
3588 103109-103118 Chemical denotes Aliskiren MESH:C446481
3589 103590-103599 Chemical denotes CaNa2EDTA
3590 103603-103616 Chemical denotes nicotianamine MESH:C082893
3591 102683-102695 Disease denotes hypertension MESH:D006973
3592 102774-102782 Disease denotes COVID-19 MESH:C000657245
3593 102818-102838 Disease denotes SARS-CoV-2 infection MESH:C000657245
3594 102884-102892 Disease denotes COVID-19 MESH:C000657245
3595 102893-102900 Disease denotes hypoxia MESH:D000860
3596 103064-103077 Disease denotes hyperactivity MESH:D006948
3597 103367-103387 Disease denotes SARS-CoV-2 infection MESH:C000657245
3599 103688-103697 Chemical denotes CaNa2EDTA
3623 103844-103848 Gene denotes ACE2 Gene:59272
3624 103853-103856 Gene denotes ACE Gene:59272
3625 103884-103888 Gene denotes ACE2 Gene:59272
3626 103894-103897 Gene denotes ACE Gene:59272
3627 105266-105269 Gene denotes ACE Gene:59272
3628 105274-105278 Gene denotes ACE2 Gene:59272
3629 104177-104182 Gene denotes renin Gene:5972
3630 104667-104675 Gene denotes Ang-(1–7 Gene:284
3631 104733-104741 Species denotes patients Tax:9606
3632 105247-105255 Species denotes patients Tax:9606
3633 105007-105016 Chemical denotes CaNa2EDTA
3634 103794-103807 Disease denotes hyperactivity MESH:D006948
3635 104043-104063 Disease denotes SARS-CoV-2 infection MESH:C000657245
3636 104106-104113 Disease denotes hypoxia MESH:D000860
3637 104342-104350 Disease denotes COVID-19 MESH:C000657245
3638 104417-104437 Disease denotes SARS-CoV-2 infection MESH:C000657245
3639 104560-104564 Disease denotes ARDS MESH:D012128
3640 104614-104621 Disease denotes hypoxia MESH:D000860
3641 104626-104641 Disease denotes cardiac failure MESH:D006333
3642 104756-104760 Disease denotes ARDS MESH:D012128
3643 104792-104815 Disease denotes coronary artery disease MESH:D003324
3644 104926-104938 Disease denotes dysfunctions MESH:D009461
3645 105020-105042 Disease denotes coronary heart disease MESH:D003324
3669 106245-106248 Species denotes men Tax:9606
3670 106826-106834 Species denotes patients Tax:9606
3671 108080-108087 Species denotes patient Tax:9606
3672 105701-105708 Chemical denotes calcium MESH:D002118
3673 105717-105726 Chemical denotes CaNa2EDTA
3674 105839-105848 Chemical denotes CaNa2EDTA
3675 106054-106063 Chemical denotes CaNa2EDTA
3676 106319-106328 Chemical denotes CaNa2EDTA
3677 106361-106370 Chemical denotes CaNa2EDTA
3678 106582-106591 Chemical denotes CaNa2EDTA
3679 106686-106695 Chemical denotes CaNa2EDTA
3680 106908-106917 Chemical denotes CaNa2EDTA
3681 107112-107121 Chemical denotes CaNa2EDTA
3682 107194-107199 Chemical denotes metal MESH:D008670
3683 107314-107318 Chemical denotes EDTA MESH:D004492
3684 107604-107613 Chemical denotes CaNa2EDTA
3685 107884-107893 Chemical denotes CaNa2EDTA
3686 105785-105794 Disease denotes poisoning MESH:D011041
3687 106717-106726 Disease denotes poisoning MESH:D011041
3688 107085-107092 Disease denotes painful MESH:D010146
3689 107926-107934 Disease denotes COVID-19 MESH:C000657245
3690 108041-108049 Disease denotes COVID-19 MESH:C000657245
3691 108159-108167 Disease denotes toxicity MESH:D064420
3701 108426-108430 Gene denotes AT1R Gene:185
3702 108439-108443 Gene denotes AT2R Gene:24182
3703 108434-108438 Gene denotes MasR Gene:116511
3704 108571-108579 Species denotes patients Tax:9606
3705 108301-108312 Disease denotes dysfunction MESH:D009461
3706 108332-108351 Disease denotes cardiac dysfunction MESH:D006331
3707 108369-108379 Disease denotes thrombosis MESH:D013927
3708 108534-108545 Disease denotes dysfunction MESH:D009461
3709 108581-108589 Disease denotes COVID-19 MESH:C000657245
3733 109206-109213 Gene denotes albumin Gene:213
3734 109215-109220 Gene denotes IL-10 Gene:3586
3735 109222-109230 Gene denotes Ang (1–9 Gene:284
3736 109244-109252 Gene denotes Ang (1–5 Gene:284
3737 109261-109271 Gene denotes bradykinin Gene:3827
3738 109330-109333 Gene denotes ACE Gene:59272
3739 109341-109345 Gene denotes ACE2 Gene:59272
3740 109425-109428 Gene denotes ACE Gene:59272
3741 109433-109437 Gene denotes ACE2 Gene:59272
3742 110172-110176 Gene denotes ACE2 Gene:59272
3743 109233-109241 Gene denotes Ang (1–7 Gene:284
3744 109184-109191 Gene denotes albumin Gene:213
3745 109518-109526 Species denotes patients Tax:9606
3746 109669-109677 Species denotes patients Tax:9606
3747 109877-109884 Species denotes patient Tax:9606
3748 109164-109168 Chemical denotes Zn2+
3749 108926-108938 Disease denotes dysfunctions MESH:D009461
3750 109075-109083 Disease denotes COVID-19 MESH:C000657245
3751 109509-109517 Disease denotes COVID-19 MESH:C000657245
3752 109543-109571 Disease denotes eosinopaenia and hypotension MESH:D007022
3753 110039-110051 Disease denotes inflammation MESH:D007249
3754 110252-110272 Disease denotes SARS-CoV-2 infection MESH:C000657245
3755 110345-110353 Disease denotes COVID-19 MESH:C000657245
3762 110818-110822 Gene denotes ACE2 Gene:59272
3763 110887-110891 Gene denotes ACE2 Gene:59272
3764 111019-111027 Species denotes patients Tax:9606
3765 110576-110584 Disease denotes COVID-19 MESH:C000657245
3766 110657-110665 Disease denotes COVID-19 MESH:C000657245
3767 111314-111321 Disease denotes failure MESH:D006333

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T7 26-73 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T8 26-59 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T9 75-83 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T10 75-79 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T11 87-96 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T12 117-125 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T13 255-263 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T14 264-273 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T15 441-449 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T16 441-445 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T17 452-461 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T18 557-590 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T19 592-596 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T20 930-934 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T21 983-989 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T22 1021-1033 Disease denotes coagulopathy http://purl.obolibrary.org/obo/MONDO_0001531
T23 1053-1061 Disease denotes acidosis http://purl.obolibrary.org/obo/MONDO_0006022
T24 1178-1190 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T25 1349-1355 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T26 1458-1466 Disease denotes allergic http://purl.obolibrary.org/obo/MONDO_0004980
T27 1570-1576 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T28 1638-1654 Disease denotes Viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T29 1684-1700 Disease denotes allergic disease http://purl.obolibrary.org/obo/MONDO_0005271
T30 1684-1692 Disease denotes allergic http://purl.obolibrary.org/obo/MONDO_0004980
T31 1984-1988 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T32 2011-2031 Disease denotes hypertensive disease http://purl.obolibrary.org/obo/MONDO_0005044
T33 2122-2137 Disease denotes virus infection http://purl.obolibrary.org/obo/MONDO_0005108
T34 2128-2137 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T35 2182-2194 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T36 2351-2368 Disease denotes allergic diseases http://purl.obolibrary.org/obo/MONDO_0005271
T37 2351-2359 Disease denotes allergic http://purl.obolibrary.org/obo/MONDO_0004980
T38 2442-2446 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T39 2599-2607 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T40 2645-2666 Disease denotes chronic renal disease http://purl.obolibrary.org/obo/MONDO_0005300
T41 2653-2666 Disease denotes renal disease http://purl.obolibrary.org/obo/MONDO_0002118|http://purl.obolibrary.org/obo/MONDO_0005240
T43 2802-2824 Disease denotes chronic kidney disease http://purl.obolibrary.org/obo/MONDO_0005300
T44 2810-2824 Disease denotes kidney disease http://purl.obolibrary.org/obo/MONDO_0001343|http://purl.obolibrary.org/obo/MONDO_0005240
T46 2858-2866 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T47 2874-2880 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T48 2909-2917 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T49 2909-2913 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T50 2922-2930 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T51 2922-2926 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T52 3041-3049 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T53 3041-3045 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T54 3258-3275 Disease denotes acute lung injury http://purl.obolibrary.org/obo/MONDO_0006502|http://purl.obolibrary.org/obo/MONDO_0015796
T56 3269-3275 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T57 3287-3295 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T58 3287-3291 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T59 3545-3554 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T60 4150-4158 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T61 4515-4523 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T62 4515-4519 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T63 4757-4772 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T64 4763-4772 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T65 4942-4953 Disease denotes common cold http://purl.obolibrary.org/obo/MONDO_0005709
T66 4992-4996 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T67 5072-5090 Disease denotes SARS-CoV infection http://purl.obolibrary.org/obo/MONDO_0005091
T68 5072-5076 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T69 5081-5090 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T70 5220-5235 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T71 5226-5235 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T72 5396-5407 Disease denotes hypotension http://purl.obolibrary.org/obo/MONDO_0005468
T73 5514-5522 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T74 5514-5518 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T75 6061-6069 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T76 6061-6065 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T77 6106-6115 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T78 6236-6245 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T79 6530-6538 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T80 6530-6534 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T81 6636-6644 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T82 6636-6640 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T83 6702-6710 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T84 6702-6706 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T85 6734-6740 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T86 6794-6802 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T87 6794-6798 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T88 7091-7095 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T89 7278-7282 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T90 8118-8127 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T91 8163-8171 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T92 8163-8167 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T93 8188-8197 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T94 8293-8301 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T95 8293-8297 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T96 9570-9574 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T97 9898-9907 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T98 10002-10010 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T99 10380-10388 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T100 10380-10384 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T101 10448-10456 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T102 10448-10452 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T103 10552-10560 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T104 10552-10556 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T105 10870-10878 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T106 10870-10874 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T107 11083-11091 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T108 11083-11087 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T109 11236-11244 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T110 11322-11330 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T111 11405-11413 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T112 11405-11409 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T113 11658-11674 Disease denotes Kawasaki disease http://purl.obolibrary.org/obo/MONDO_0012727
T114 11989-11997 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T115 11989-11993 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T116 12154-12162 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T117 12154-12158 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T118 12523-12532 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T119 12678-12686 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T120 12758-12766 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T121 13311-13322 Disease denotes hypotension http://purl.obolibrary.org/obo/MONDO_0005468
T122 13826-13838 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T123 13870-13880 Disease denotes thrombosis http://purl.obolibrary.org/obo/MONDO_0000831
T124 14387-14399 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T125 14468-14477 Disease denotes cirrhosis http://purl.obolibrary.org/obo/MONDO_0005155
T126 14487-14493 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T127 14857-14884 Disease denotes increases in blood pressure http://purl.obolibrary.org/obo/MONDO_0005044
T128 15228-15238 Disease denotes arrhythmia http://purl.obolibrary.org/obo/MONDO_0007263
T129 15253-15276 Disease denotes ventricular tachycardia http://purl.obolibrary.org/obo/MONDO_0005477
T130 15290-15314 Disease denotes ventricular fibrillation http://purl.obolibrary.org/obo/MONDO_0000190
T131 15583-15604 Disease denotes myocardial infarction http://purl.obolibrary.org/obo/MONDO_0005068
T132 15910-15931 Disease denotes myocardial infarction http://purl.obolibrary.org/obo/MONDO_0005068
T133 15965-15987 Disease denotes cardiovascular disease http://purl.obolibrary.org/obo/MONDO_0004995
T134 16071-16081 Disease denotes thrombosis http://purl.obolibrary.org/obo/MONDO_0000831
T135 16157-16167 Disease denotes thrombosis http://purl.obolibrary.org/obo/MONDO_0000831
T136 16181-16189 Disease denotes thrombus http://purl.obolibrary.org/obo/MONDO_0000831
T137 16330-16340 Disease denotes thrombosis http://purl.obolibrary.org/obo/MONDO_0000831
T138 16588-16598 Disease denotes thrombosis http://purl.obolibrary.org/obo/MONDO_0000831
T139 16755-16765 Disease denotes thrombosis http://purl.obolibrary.org/obo/MONDO_0000831
T140 16780-16818 Disease denotes disseminated intravascular coagulation http://purl.obolibrary.org/obo/MONDO_0001243
T141 16968-16979 Disease denotes proteinuria http://purl.obolibrary.org/obo/MONDO_0003634
T142 17193-17204 Disease denotes hepatitis C http://purl.obolibrary.org/obo/MONDO_0005231
T143 17193-17202 Disease denotes hepatitis http://purl.obolibrary.org/obo/MONDO_0002251
T144 17205-17214 Disease denotes cirrhosis http://purl.obolibrary.org/obo/MONDO_0005155
T145 18106-18119 Disease denotes heart disease http://purl.obolibrary.org/obo/MONDO_0005267
T146 18496-18499 Disease denotes AT1 http://purl.obolibrary.org/obo/MONDO_0008840
T147 18526-18548 Disease denotes pulmonary hypertensive http://purl.obolibrary.org/obo/MONDO_0005149
T148 19124-19132 Disease denotes acidosis http://purl.obolibrary.org/obo/MONDO_0006022
T149 19178-19182 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T150 19723-19727 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T151 20326-20352 Disease denotes inflammatory bowel disease http://purl.obolibrary.org/obo/MONDO_0005265
T152 20834-20846 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T153 20850-20868 Disease denotes pulmonary fibrosis http://purl.obolibrary.org/obo/MONDO_0002771
T154 21205-21213 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T155 21251-21259 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T156 21251-21255 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T157 21367-21371 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T158 21389-21404 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T159 21395-21404 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T160 22314-22322 Disease denotes allergic http://purl.obolibrary.org/obo/MONDO_0004980
T161 22330-22342 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T162 22403-22409 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T163 22473-22479 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T164 22525-22531 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T165 23225-23233 Disease denotes allergic http://purl.obolibrary.org/obo/MONDO_0004980
T166 23234-23246 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T167 23584-23592 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T168 23749-23757 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T169 25718-25721 Disease denotes AT1 http://purl.obolibrary.org/obo/MONDO_0008840
T170 25861-25864 Disease denotes AT1 http://purl.obolibrary.org/obo/MONDO_0008840
T171 25957-25965 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T172 25957-25961 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T173 25968-25977 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T174 26225-26233 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T175 26225-26229 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T176 26585-26593 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T177 26585-26589 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T178 26648-26656 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T179 26771-26779 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T180 26771-26775 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T181 26883-26891 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T182 26883-26887 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T183 27012-27020 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T184 27012-27016 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T185 27176-27180 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T186 27292-27300 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T187 27292-27296 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T188 27550-27558 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T189 27550-27554 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T190 27572-27580 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T191 27572-27576 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T192 27750-27758 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T193 27750-27754 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T194 28332-28340 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T195 28332-28336 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T196 28369-28378 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T197 28426-28444 Disease denotes SARS-CoV infection http://purl.obolibrary.org/obo/MONDO_0005091
T198 28426-28430 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T199 28435-28444 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T200 28728-28736 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T201 28728-28732 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T202 28985-28993 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T203 28985-28989 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T204 29175-29190 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T205 29181-29190 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T206 29660-29668 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T207 29660-29664 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T208 29755-29766 Disease denotes Hypotension http://purl.obolibrary.org/obo/MONDO_0005468
T209 30141-30156 Disease denotes virus infection http://purl.obolibrary.org/obo/MONDO_0005108
T210 30147-30156 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T211 30203-30213 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T212 30357-30365 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T213 30357-30361 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T214 30368-30377 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T215 31031-31041 Disease denotes thrombosis http://purl.obolibrary.org/obo/MONDO_0000831
T216 31150-31158 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T217 31150-31154 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T218 31590-31601 Disease denotes hypotension http://purl.obolibrary.org/obo/MONDO_0005468
T219 31617-31625 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T220 31617-31621 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T221 31885-31901 Disease denotes systemic disease http://purl.obolibrary.org/obo/MONDO_0015938
T222 31959-31967 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T223 31959-31963 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T224 32153-32161 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T225 33210-33218 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T226 33210-33214 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T227 33794-33802 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T228 33923-33941 Disease denotes immune suppression http://purl.obolibrary.org/obo/MONDO_0007816
T229 34493-34497 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T230 36096-36102 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T231 36481-36491 Disease denotes arrhythmia http://purl.obolibrary.org/obo/MONDO_0007263
T232 37004-37012 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T233 38359-38370 Disease denotes hypotension http://purl.obolibrary.org/obo/MONDO_0005468
T234 39070-39078 Disease denotes COVID–19 http://purl.obolibrary.org/obo/MONDO_0100096
T235 39272-39280 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T236 39558-39566 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T237 39558-39562 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T238 39587-39622 Disease denotes adult respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T239 39593-39622 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T240 39624-39628 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T241 39632-39640 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T242 39702-39728 Disease denotes inflammatory bowel disease http://purl.obolibrary.org/obo/MONDO_0005265
T243 39730-39733 Disease denotes IBD http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265
T245 40212-40216 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T246 40394-40398 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T247 41526-41530 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T248 41622-41626 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T249 41672-41680 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T250 41920-41936 Disease denotes allergic disease http://purl.obolibrary.org/obo/MONDO_0005271
T251 41920-41928 Disease denotes allergic http://purl.obolibrary.org/obo/MONDO_0004980
T252 41950-41972 Disease denotes chronic kidney disease http://purl.obolibrary.org/obo/MONDO_0005300
T253 41958-41972 Disease denotes kidney disease http://purl.obolibrary.org/obo/MONDO_0001343|http://purl.obolibrary.org/obo/MONDO_0005240
T255 42003-42025 Disease denotes cardiovascular disease http://purl.obolibrary.org/obo/MONDO_0004995
T256 42063-42071 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T257 42212-42233 Disease denotes chronic renal disease http://purl.obolibrary.org/obo/MONDO_0005300
T258 42220-42233 Disease denotes renal disease http://purl.obolibrary.org/obo/MONDO_0002118|http://purl.obolibrary.org/obo/MONDO_0005240
T260 42400-42422 Disease denotes chronic renal diseases http://purl.obolibrary.org/obo/MONDO_0005300
T261 42444-42448 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T262 42611-42617 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T263 42723-42729 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T264 42990-42994 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T265 43050-43058 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T266 43249-43253 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T267 43291-43299 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T268 43343-43346 Disease denotes flu http://purl.obolibrary.org/obo/MONDO_0005812
T269 43517-43526 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T270 43808-43816 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T271 44243-44251 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T272 44567-44598 Disease denotes pulmonary arterial hypertension http://purl.obolibrary.org/obo/MONDO_0015924|http://purl.obolibrary.org/obo/MONDO_0024533
T274 44586-44598 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T275 44600-44603 Disease denotes PAH http://purl.obolibrary.org/obo/MONDO_0015924
T276 44616-44624 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T277 44616-44620 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T278 44847-44851 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T279 44853-44856 Disease denotes PAH http://purl.obolibrary.org/obo/MONDO_0015924
T280 44861-44869 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T281 44861-44865 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T282 44870-44880 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T283 48789-48812 Disease denotes cardiovascular diseases http://purl.obolibrary.org/obo/MONDO_0004995
T284 48814-48832 Disease denotes metabolic syndrome http://purl.obolibrary.org/obo/MONDO_0004955
T285 48834-48846 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T286 48868-48876 Disease denotes diabetes http://purl.obolibrary.org/obo/MONDO_0005015
T287 48881-48891 Disease denotes thrombosis http://purl.obolibrary.org/obo/MONDO_0000831
T288 48967-48974 Disease denotes amyloid http://purl.obolibrary.org/obo/MONDO_0019065
T289 49008-49027 Disease denotes Alzheimer’s disease http://purl.obolibrary.org/obo/MONDO_0004975
T290 49171-49196 Disease denotes neurodegenerative disease http://purl.obolibrary.org/obo/MONDO_0005559
T291 49466-49474 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T292 49722-49748 Disease denotes neurodegenerative diseases http://purl.obolibrary.org/obo/MONDO_0005559
T293 49896-49899 Disease denotes FFA http://purl.obolibrary.org/obo/MONDO_0016776
T294 50196-50199 Disease denotes FFA http://purl.obolibrary.org/obo/MONDO_0016776
T295 50353-50365 Disease denotes dyslipidemia http://purl.obolibrary.org/obo/MONDO_0002525
T296 50721-50728 Disease denotes amyloid http://purl.obolibrary.org/obo/MONDO_0019065
T297 50774-50793 Disease denotes Alzheimer’s disease http://purl.obolibrary.org/obo/MONDO_0004975
T298 51335-51338 Disease denotes IBD http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265
T300 51340-51344 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T301 51349-51357 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T302 51449-51453 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T303 51700-51704 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T304 51799-51803 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T305 51829-51847 Disease denotes multiorgan failure http://purl.obolibrary.org/obo/MONDO_0043726
T306 52119-52138 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T307 52261-52267 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T308 52378-52400 Disease denotes pulmonary hypertension http://purl.obolibrary.org/obo/MONDO_0005149
T309 52388-52400 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T310 52760-52768 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T311 53372-53376 Disease denotes clam http://purl.obolibrary.org/obo/MONDO_0011948
T312 56490-56498 Disease denotes acidosis http://purl.obolibrary.org/obo/MONDO_0006022
T313 56522-56526 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T314 57810-57836 Disease denotes increase of blood pressure http://purl.obolibrary.org/obo/MONDO_0005044
T315 58655-58661 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T316 59206-59218 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T317 59688-59709 Disease denotes myocardial infarction http://purl.obolibrary.org/obo/MONDO_0005068
T318 60136-60157 Disease denotes myocardial infarction http://purl.obolibrary.org/obo/MONDO_0005068
T319 60209-60217 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T320 60553-60560 Disease denotes colitis http://purl.obolibrary.org/obo/MONDO_0005292
T321 63697-63705 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T322 64286-64294 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T323 64497-64505 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T324 64506-64515 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T325 64851-64862 Disease denotes arrhythmias http://purl.obolibrary.org/obo/MONDO_0007263
T326 64887-64898 Disease denotes hypotension http://purl.obolibrary.org/obo/MONDO_0005468
T327 64937-64952 Disease denotes agranulocytosis http://purl.obolibrary.org/obo/MONDO_0001609
T328 64978-64988 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T329 65145-65166 Disease denotes renal artery diseases http://purl.obolibrary.org/obo/MONDO_0002286
T330 66826-66834 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T331 66826-66830 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T332 66932-66940 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T333 66932-66936 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T334 69081-69099 Disease denotes SARS-CoV infection http://purl.obolibrary.org/obo/MONDO_0005091
T335 69081-69085 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T336 69090-69099 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T337 69201-69209 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T338 69201-69205 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T339 69278-69293 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T340 69284-69293 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T341 69386-69394 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T342 69408-69412 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T343 69417-69420 Disease denotes PAH http://purl.obolibrary.org/obo/MONDO_0015924
T344 69702-69710 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T345 69759-69763 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T346 69768-69771 Disease denotes PAH http://purl.obolibrary.org/obo/MONDO_0015924
T347 69987-69995 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T348 70015-70023 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T349 70075-70087 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T350 70089-70097 Disease denotes diabetes http://purl.obolibrary.org/obo/MONDO_0005015
T351 70331-70343 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T352 70903-70915 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T353 70917-70925 Disease denotes diabetes http://purl.obolibrary.org/obo/MONDO_0005015
T354 70927-70939 Disease denotes dyslipidemia http://purl.obolibrary.org/obo/MONDO_0002525
T355 71126-71134 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T356 71615-71618 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T357 71914-71917 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T358 72263-72266 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T359 72391-72394 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T360 72481-72484 Disease denotes AT1 http://purl.obolibrary.org/obo/MONDO_0008840
T361 72658-72666 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T362 72808-72811 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T363 72948-72951 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T364 72981-72989 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T365 73007-73010 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T366 73084-73092 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T367 73156-73159 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T368 73204-73212 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T369 73222-73225 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T370 73311-73314 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T371 73432-73440 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T372 73490-73493 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T373 73850-73858 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T374 74049-74052 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T375 74119-74123 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T376 74191-74207 Disease denotes face the disease http://purl.obolibrary.org/obo/MONDO_0044987
T377 74279-74287 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T378 75063-75069 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T379 75080-75097 Disease denotes allergic diseases http://purl.obolibrary.org/obo/MONDO_0005271
T380 75080-75088 Disease denotes allergic http://purl.obolibrary.org/obo/MONDO_0004980
T381 75129-75137 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T382 75315-75338 Disease denotes cardiovascular diseases http://purl.obolibrary.org/obo/MONDO_0004995
T383 75344-75370 Disease denotes inflammatory bowel disease http://purl.obolibrary.org/obo/MONDO_0005265
T384 75504-75512 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T385 75544-75563 Disease denotes atrial fibrillation http://purl.obolibrary.org/obo/MONDO_0004981
T386 75692-75704 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T387 75720-75736 Disease denotes vascular disease http://purl.obolibrary.org/obo/MONDO_0005385
T388 75889-75897 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T389 75968-75972 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T390 76095-76110 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T391 76101-76110 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T392 76317-76325 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T393 76416-76424 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T394 76521-76542 Disease denotes chronic renal disease http://purl.obolibrary.org/obo/MONDO_0005300
T395 76529-76542 Disease denotes renal disease http://purl.obolibrary.org/obo/MONDO_0002118|http://purl.obolibrary.org/obo/MONDO_0005240
T397 76546-76554 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T398 76734-76756 Disease denotes chronic kidney disease http://purl.obolibrary.org/obo/MONDO_0005300
T399 76742-76756 Disease denotes kidney disease http://purl.obolibrary.org/obo/MONDO_0001343|http://purl.obolibrary.org/obo/MONDO_0005240
T401 76787-76809 Disease denotes cardiovascular disease http://purl.obolibrary.org/obo/MONDO_0004995
T402 76948-76959 Disease denotes proteinuria http://purl.obolibrary.org/obo/MONDO_0003634
T403 77026-77048 Disease denotes chronic kidney disease http://purl.obolibrary.org/obo/MONDO_0005300
T404 77034-77048 Disease denotes kidney disease http://purl.obolibrary.org/obo/MONDO_0001343|http://purl.obolibrary.org/obo/MONDO_0005240
T406 77142-77164 Disease denotes chronic renal diseases http://purl.obolibrary.org/obo/MONDO_0005300
T407 77185-77189 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T408 77372-77394 Disease denotes chronic renal diseases http://purl.obolibrary.org/obo/MONDO_0005300
T409 77473-77476 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T410 77672-77680 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T411 77778-77788 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T412 77799-77807 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T413 77799-77803 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T414 77889-77897 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T415 77889-77893 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T416 77900-77909 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T417 78169-78181 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T418 78183-78195 Disease denotes dyslipidemia http://purl.obolibrary.org/obo/MONDO_0002525
T419 78197-78212 Disease denotes type 2 diabetes http://purl.obolibrary.org/obo/MONDO_0005148
T420 78204-78212 Disease denotes diabetes http://purl.obolibrary.org/obo/MONDO_0005015
T421 78543-78551 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T422 78580-78603 Disease denotes obstructive sleep apnea http://purl.obolibrary.org/obo/MONDO_0007147
T423 78592-78603 Disease denotes sleep apnea http://purl.obolibrary.org/obo/MONDO_0005296
T424 78605-78608 Disease denotes OSA http://purl.obolibrary.org/obo/MONDO_0007147
T425 78653-78656 Disease denotes OSA http://purl.obolibrary.org/obo/MONDO_0007147
T426 78661-78669 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T427 78717-78720 Disease denotes OSA http://purl.obolibrary.org/obo/MONDO_0007147
T428 78724-78732 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T429 78787-78790 Disease denotes OSA http://purl.obolibrary.org/obo/MONDO_0007147
T430 78844-78847 Disease denotes OSA http://purl.obolibrary.org/obo/MONDO_0007147
T431 78982-79018 Disease denotes hypertension, cardiovascular disease http://purl.obolibrary.org/obo/MONDO_0001302
T432 78982-78994 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T433 78996-79018 Disease denotes cardiovascular disease http://purl.obolibrary.org/obo/MONDO_0004995
T434 79020-79028 Disease denotes diabetes http://purl.obolibrary.org/obo/MONDO_0005015
T435 79030-79037 Disease denotes obesity http://purl.obolibrary.org/obo/MONDO_0011122
T436 79051-79063 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T437 79255-79258 Disease denotes OSA http://purl.obolibrary.org/obo/MONDO_0007147
T438 79306-79314 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T439 79306-79310 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T440 79317-79326 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T441 79331-79334 Disease denotes OSA http://purl.obolibrary.org/obo/MONDO_0007147
T442 79555-79558 Disease denotes OSA http://purl.obolibrary.org/obo/MONDO_0007147
T443 79779-79787 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T444 80239-80247 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T445 80239-80243 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T446 80292-80295 Disease denotes flu http://purl.obolibrary.org/obo/MONDO_0005812
T447 80322-80331 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T448 80385-80396 Disease denotes common cold http://purl.obolibrary.org/obo/MONDO_0005709
T449 80533-80536 Disease denotes flu http://purl.obolibrary.org/obo/MONDO_0005812
T450 80646-80654 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T451 80646-80650 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T452 80704-80712 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T453 80704-80708 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T454 80715-80724 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T455 81024-81040 Disease denotes virus infections http://purl.obolibrary.org/obo/MONDO_0005108
T456 81052-81060 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T457 81052-81056 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T458 81356-81364 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T459 81491-81499 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T460 81491-81495 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T461 81502-81511 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T462 81588-81596 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T463 81612-81620 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T464 81612-81616 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T465 81728-81736 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T466 81891-81895 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T467 82009-82017 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T468 82009-82013 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T469 82091-82099 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T470 82091-82095 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T471 82158-82166 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T472 82158-82162 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T473 82196-82202 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T474 82264-82272 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T475 82264-82268 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T476 82476-82494 Disease denotes SARS-CoV infection http://purl.obolibrary.org/obo/MONDO_0005091
T477 82476-82480 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T478 82485-82494 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T479 82521-82527 Disease denotes asthma http://purl.obolibrary.org/obo/MONDO_0004979
T480 82587-82605 Disease denotes SARS-CoV infection http://purl.obolibrary.org/obo/MONDO_0005091
T481 82587-82591 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T482 82596-82605 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T483 82845-82854 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T484 82944-82955 Disease denotes hypotension http://purl.obolibrary.org/obo/MONDO_0005468
T485 82966-82974 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T486 83103-83111 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T487 83103-83107 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T488 83568-83576 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T489 83858-83862 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T490 83883-83889 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T491 84403-84411 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T492 84403-84407 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T493 84806-84814 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T494 85737-85745 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T495 86397-86405 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T496 86496-86504 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T497 86496-86500 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T498 86703-86709 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T499 86892-86903 Disease denotes hypotension http://purl.obolibrary.org/obo/MONDO_0005468
T500 86924-86932 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T501 86993-87028 Disease denotes Acute Respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T502 86999-87028 Disease denotes Respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T503 87032-87040 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T504 87060-87091 Disease denotes pulmonary arterial hypertension http://purl.obolibrary.org/obo/MONDO_0015924|http://purl.obolibrary.org/obo/MONDO_0024533
T506 87079-87091 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T507 87134-87169 Disease denotes Acute Respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T508 87140-87169 Disease denotes Respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T509 87240-87244 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T510 87338-87342 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T511 87412-87418 Disease denotes trauma http://purl.obolibrary.org/obo/MONDO_0021178
T512 87420-87438 Disease denotes acute pancreatitis http://purl.obolibrary.org/obo/MONDO_0006515
T513 87426-87438 Disease denotes pancreatitis http://purl.obolibrary.org/obo/MONDO_0004982
T514 87443-87453 Disease denotes pneumonias http://purl.obolibrary.org/obo/MONDO_0005249
T515 87464-87480 Disease denotes virus infections http://purl.obolibrary.org/obo/MONDO_0005108
T516 87489-87493 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T517 87508-87517 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T518 87590-87594 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T519 87651-87655 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T520 87799-87803 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T521 87993-87997 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T522 88046-88049 Disease denotes PAH http://purl.obolibrary.org/obo/MONDO_0015924
T523 88112-88120 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T524 88311-88315 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T525 88573-88577 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T526 88629-88633 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T527 90538-90542 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T528 91178-91182 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T529 91900-91904 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T530 92314-92318 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T531 92516-92520 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T532 92919-92923 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T533 93524-93528 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T534 93729-93733 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T535 93884-93888 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T536 94197-94200 Disease denotes PAH http://purl.obolibrary.org/obo/MONDO_0015924
T537 94205-94229 Disease denotes coronary atherosclerosis http://purl.obolibrary.org/obo/MONDO_0021661
T538 94214-94229 Disease denotes atherosclerosis http://purl.obolibrary.org/obo/MONDO_0005311
T539 94429-94452 Disease denotes coronary artery disease http://purl.obolibrary.org/obo/MONDO_0005010
T540 94438-94452 Disease denotes artery disease http://purl.obolibrary.org/obo/MONDO_0000473
T541 94585-94588 Disease denotes PAH http://purl.obolibrary.org/obo/MONDO_0015924
T542 94940-94948 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T543 95041-95049 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T544 95232-95240 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T545 95232-95236 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T546 96002-96009 Disease denotes colitis http://purl.obolibrary.org/obo/MONDO_0005292
T547 96902-96910 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T548 97127-97135 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T549 97470-97478 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T550 97713-97721 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T551 97713-97717 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T552 98307-98310 Disease denotes DLM http://purl.obolibrary.org/obo/MONDO_0016745
T553 98488-98495 Disease denotes sterile http://purl.obolibrary.org/obo/MONDO_0005047
T554 98660-98663 Disease denotes DLM http://purl.obolibrary.org/obo/MONDO_0016745
T555 99155-99168 Disease denotes inflammations http://purl.obolibrary.org/obo/MONDO_0021166
T556 99170-99196 Disease denotes Inflammatory bowel disease http://purl.obolibrary.org/obo/MONDO_0005265
T557 99198-99207 Disease denotes gastritis http://purl.obolibrary.org/obo/MONDO_0004966
T558 99212-99219 Disease denotes colitis http://purl.obolibrary.org/obo/MONDO_0005292
T559 100243-100255 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T560 100334-100338 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T561 101123-101131 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T562 101919-101927 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T563 102683-102695 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T564 102774-102782 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T565 102818-102826 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T566 102818-102822 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T567 102829-102838 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T568 102884-102892 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T569 103367-103375 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T570 103367-103371 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T571 103378-103387 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T572 104043-104051 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T573 104043-104047 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T574 104054-104063 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T575 104342-104350 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T576 104417-104425 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T577 104417-104421 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T578 104428-104437 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T579 104560-104564 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T580 104566-104569 Disease denotes PAH http://purl.obolibrary.org/obo/MONDO_0015924
T581 104626-104641 Disease denotes cardiac failure http://purl.obolibrary.org/obo/MONDO_0005252
T582 104756-104760 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T583 104765-104768 Disease denotes PAH http://purl.obolibrary.org/obo/MONDO_0015924
T584 104792-104815 Disease denotes coronary artery disease http://purl.obolibrary.org/obo/MONDO_0005010
T585 104801-104815 Disease denotes artery disease http://purl.obolibrary.org/obo/MONDO_0000473
T586 105020-105042 Disease denotes coronary heart disease http://purl.obolibrary.org/obo/MONDO_0005010
T587 105029-105042 Disease denotes heart disease http://purl.obolibrary.org/obo/MONDO_0005267
T588 105780-105794 Disease denotes lead poisoning http://purl.obolibrary.org/obo/MONDO_0018019
T589 105785-105794 Disease denotes poisoning http://purl.obolibrary.org/obo/MONDO_0029000
T590 106712-106726 Disease denotes lead poisoning http://purl.obolibrary.org/obo/MONDO_0018019
T591 106717-106726 Disease denotes poisoning http://purl.obolibrary.org/obo/MONDO_0029000
T592 107200-107210 Disease denotes poisonings http://purl.obolibrary.org/obo/MONDO_0029000
T593 107926-107934 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T594 108041-108049 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T595 108369-108379 Disease denotes thrombosis http://purl.obolibrary.org/obo/MONDO_0000831
T596 108581-108589 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T597 109075-109083 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T598 109509-109517 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T599 109560-109571 Disease denotes hypotension http://purl.obolibrary.org/obo/MONDO_0005468
T600 110039-110051 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T601 110252-110260 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T602 110252-110256 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T603 110263-110272 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T604 110345-110353 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T605 110414-110417 Disease denotes flu http://purl.obolibrary.org/obo/MONDO_0005812
T606 110576-110584 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T607 110657-110665 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 99018-99024 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T2 99074-99080 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T3 99139-99154 http://purl.obolibrary.org/obo/UBERON_0001555 denotes digestive tract
T4 99273-99274 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T5 99292-99299 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T6 99644-99649 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T7 99644-99649 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T8 99826-99832 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T9 99866-99867 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T10 100077-100081 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T11 100077-100081 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T12 100111-100119 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T13 100238-100242 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T14 100238-100242 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T15 100719-100720 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T16 100828-100832 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T17 100875-100876 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T18 101029-101037 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T19 101308-101316 http://purl.obolibrary.org/obo/CLO_0001658 denotes actively
T20 101333-101337 http://purl.obolibrary.org/obo/UBERON_0001456 denotes face
T21 101453-101455 http://purl.obolibrary.org/obo/CLO_0050475 denotes my
T22 101687-101688 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T23 101755-101760 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T24 101755-101760 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T25 101755-101760 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T26 101755-101760 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T27 101761-101765 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T28 101761-101765 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T29 101766-101771 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T30 101766-101771 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T31 101772-101781 http://purl.obolibrary.org/obo/UBERON_0000160 denotes intestine
T32 101772-101781 http://www.ebi.ac.uk/efo/EFO_0000834 denotes intestine
T33 101782-101788 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T34 101782-101788 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T35 101782-101788 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T36 101789-101802 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T37 101803-101808 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T38 101803-101808 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T39 101950-101955 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T40 101950-101955 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T41 101981-101989 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T42 102028-102036 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T43 102040-102045 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T44 102046-102052 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T45 102091-102094 http://purl.obolibrary.org/obo/CLO_0001046 denotes 116
T46 102113-102123 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T47 102178-102186 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T48 102197-102201 http://purl.obolibrary.org/obo/UBERON_0001456 denotes face
T49 102245-102246 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T50 102361-102369 http://purl.obolibrary.org/obo/CLO_0001658 denotes Activity
T51 102479-102487 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T52 102769-102773 http://purl.obolibrary.org/obo/UBERON_0001456 denotes face
T53 102929-102933 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T54 102976-102977 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T55 103137-103140 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T56 103223-103224 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T57 103403-103406 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T58 103487-103488 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T59 103524-103528 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T60 103909-103917 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T61 103947-103951 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T62 104120-104124 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T63 104479-104483 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T64 104694-104695 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T65 104801-104807 http://purl.obolibrary.org/obo/UBERON_0001637 denotes artery
T66 104801-104807 http://www.ebi.ac.uk/efo/EFO_0000814 denotes artery
T67 104858-104862 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T68 104949-104950 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T69 105029-105034 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T70 105029-105034 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T71 105029-105034 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T72 105029-105034 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T73 105355-105365 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T74 105606-105607 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T75 105630-105631 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T76 105875-105897 http://purl.obolibrary.org/obo/UBERON_0005409 denotes gastrointestinal tract
T77 106092-106098 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T78 106125-106135 http://purl.obolibrary.org/obo/UBERON_0000160 denotes intestinal
T79 106125-106135 http://www.ebi.ac.uk/efo/EFO_0000834 denotes intestinal
T80 106202-106210 http://purl.obolibrary.org/obo/OBI_0100026 denotes organism
T81 106202-106210 http://purl.obolibrary.org/obo/UBERON_0000468 denotes organism
T82 106297-106298 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T83 106378-106379 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T84 106849-106854 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T85 106849-106854 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T86 106875-106879 http://purl.obolibrary.org/obo/CLO_0003535 denotes g/m2
T87 107010-107011 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T88 107136-107139 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T89 107222-107226 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T90 107222-107226 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T91 107768-107771 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T92 107772-107773 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T93 108070-108071 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T94 108352-108356 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T95 108352-108356 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T96 108405-108415 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T97 108593-108594 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T98 108776-108777 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T99 108800-108801 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T100 109150-109156 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T101 109356-109364 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T102 109438-109446 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T103 109938-109943 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T104 109938-109943 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T105 110009-110017 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T106 110058-110061 http://purl.obolibrary.org/obo/PR_000001343 denotes aim
T107 110122-110132 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T108 110133-110138 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T109 110405-110406 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T110 110419-110420 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T111 110625-110626 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T112 110838-110841 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T113 110871-110879 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T114 111048-111049 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T115 111233-111235 http://purl.obolibrary.org/obo/CLO_0050475 denotes my
T116 111288-111289 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T117 111312-111313 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T92165 797-806 http://www.ebi.ac.uk/efo/EFO_0000876 denotes extremely
T23402 870-871 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T30677 1075-1076 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T96031 1122-1126 http://purl.obolibrary.org/obo/CLO_0053704 denotes IL-8
T99826 1396-1399 http://purl.obolibrary.org/obo/CLO_0001414 denotes 548
T43843 1970-1975 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T60553 2094-2095 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T56639 2122-2127 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T28761 2224-2226 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T99781 2266-2268 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T70533 2416-2417 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T72708 2810-2816 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T15863 2810-2816 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T37184 2810-2816 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T27253 3001-3002 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T11956 3096-3101 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T59818 3140-3146 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T25048 3147-3157 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T45947 3158-3163 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T10170 3177-3194 http://purl.obolibrary.org/obo/CL_0000115 denotes endothelial cells
T36367 3223-3224 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T94559 3264-3268 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T18915 3264-3268 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T49004 3323-3325 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T42150 3389-3392 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T92578 3427-3437 http://purl.obolibrary.org/obo/CLO_0000031 denotes cell lines
T47002 3459-3463 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T41775 3459-3463 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T33694 3464-3469 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T62919 3627-3631 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T14814 3643-3648 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T56060 3649-3655 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T1792 3671-3677 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T85406 3765-3768 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T60699 3819-3829 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T15128 4218-4223 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T47491 4247-4252 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T61686 4253-4259 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T23099 4270-4273 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T34964 4321-4329 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T56294 4443-4448 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T5722 4532-4533 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T91276 4690-4698 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T71067 4913-4918 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T32655 5172-5180 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T83841 5349-5351 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T42024 5558-5561 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T66445 5603-5611 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1462 5644-5659 http://purl.obolibrary.org/obo/GO_0043234 denotes protein complex
T66948 5718-5726 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T82513 5781-5782 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T95692 5913-5921 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T65495 5938-5939 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T74464 5998-6002 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T56108 6025-6030 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T38701 6041-6046 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T36055 6132-6133 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T77642 6206-6207 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T15238 6275-6278 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T38031 6330-6340 http://purl.obolibrary.org/obo/UBERON_0000483 denotes epithelium
T71674 6438-6448 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T31054 6449-6454 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T46684 6729-6733 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T19001 6729-6733 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T91433 6852-6869 http://purl.obolibrary.org/obo/GO_0043234 denotes protein complexes
T66620 6976-6978 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T76112 7252-7256 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T85916 7257-7263 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T42262 7264-7272 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T4712 7377-7379 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T12859 7394-7396 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T72988 7394-7396 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T53244 7511-7513 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T93889 7514-7523 http://purl.obolibrary.org/obo/UBERON_0000033 denotes heads and
T73899 7514-7523 http://www.ebi.ac.uk/efo/EFO_0000964 denotes heads and
T50671 7524-7525 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1263 7535-7537 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T61883 7535-7537 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T24540 7594-7596 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T30598 7851-7853 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T86794 7966-7968 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T58803 7990-7992 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T15028 8044-8046 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T80157 8044-8046 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T19942 8074-8082 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T91194 8113-8117 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T77366 8252-8253 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T97236 8313-8316 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T81091 8378-8379 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T93457 8432-8437 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T78563 8459-8460 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T86342 8734-8735 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T89948 8736-8744 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T27116 8850-8854 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T53807 8855-8863 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T96275 8872-8873 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T91518 8874-8882 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T1576 9046-9050 http://www.ebi.ac.uk/efo/EFO_0000967 denotes neck
T13416 9081-9082 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T7903 9187-9190 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T48778 9265-9269 http://www.ebi.ac.uk/efo/EFO_0000967 denotes neck
T3704 9380-9382 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T6824 9380-9382 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T65411 9534-9538 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T93631 9547-9556 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membranes
T36180 9558-9559 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T98795 9607-9612 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T83678 9678-9683 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T26776 9698-9702 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T81513 9704-9705 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T17871 9791-9793 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T75662 9791-9793 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T61344 9871-9876 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T2057 9891-9897 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T72343 9917-9919 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T25654 9942-9944 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T15557 10139-10144 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T67356 10153-10156 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T824 10254-10264 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T96980 10363-10365 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T60119 10435-10437 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T36399 10493-10499 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T97656 10638-10646 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T10969 10684-10690 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T24009 10699-10704 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T60151 10738-10746 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T130 10949-10955 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T131 11101-11107 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T132 11224-11230 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T133 11478-11484 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T134 11548-11549 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T135 11691-11693 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T136 11713-11714 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T137 11760-11762 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T138 11830-11832 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T139 11851-11853 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T140 11941-11943 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T141 11979-11981 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T142 12107-12109 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T143 12297-12299 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T144 12386-12387 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T145 12422-12431 http://purl.obolibrary.org/obo/OBI_0000245 denotes organized
T146 12498-12503 http://www.ebi.ac.uk/efo/EFO_0001410 denotes armed
T147 12666-12672 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T148 12707-12708 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T149 13063-13066 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T150 13079-13086 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T151 13154-13164 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T152 13190-13198 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T153 13472-13482 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T154 13549-13550 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T155 13654-13655 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T156 13776-13786 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T157 13850-13854 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T158 13906-13910 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T159 13906-13910 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T160 13998-14006 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T161 14417-14439 http://purl.obolibrary.org/obo/UBERON_0005409 denotes gastrointestinal tract
T162 14462-14467 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T163 14482-14486 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T164 14482-14486 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T165 14511-14516 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T166 14555-14565 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T167 14641-14651 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T168 14791-14801 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T169 14870-14875 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T170 14870-14875 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T171 14954-14956 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T172 14979-14985 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T173 14992-15000 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T174 15240-15245 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T175 15240-15245 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T176 15240-15245 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T177 15240-15245 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T178 15376-15384 http://purl.obolibrary.org/obo/UBERON_0007651 denotes junction
T179 15568-15569 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T180 15624-15630 http://purl.obolibrary.org/obo/UBERON_0001637 denotes artery
T181 15624-15630 http://www.ebi.ac.uk/efo/EFO_0000814 denotes artery
T182 15664-15667 http://purl.obolibrary.org/obo/CLO_0002096 denotes C16
T183 15678-15679 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T184 15782-15792 http://purl.obolibrary.org/obo/UBERON_0002349 denotes myocardium
T185 15863-15871 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T186 15932-15937 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T187 15932-15937 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T188 15932-15937 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T189 15932-15937 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T190 15939-15941 http://purl.obolibrary.org/obo/CLO_0001407 denotes 52
T191 16276-16277 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T192 16302-16312 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T193 16402-16405 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T194 16470-16471 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T195 16472-16477 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T196 16490-16500 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T197 16710-16720 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T198 17101-17107 http://purl.obolibrary.org/obo/UBERON_0002107 denotes livers
T199 17101-17107 http://www.ebi.ac.uk/efo/EFO_0000887 denotes livers
T200 17156-17173 http://purl.obolibrary.org/obo/CL_0000115 denotes endothelial cells
T201 17187-17192 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T202 17295-17300 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T203 17412-17420 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T204 17525-17530 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T205 17525-17530 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T206 17531-17536 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T207 17543-17548 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T208 17587-17595 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T209 17633-17639 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T210 17717-17722 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T211 17723-17739 http://purl.obolibrary.org/obo/UBERON_0002012 denotes pulmonary artery
T212 17723-17739 http://www.ebi.ac.uk/efo/EFO_0001399 denotes pulmonary artery
T213 17740-17759 http://purl.obolibrary.org/obo/CL_0000192 denotes smooth muscle cells
T214 17778-17782 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T215 18007-18018 http://purl.obolibrary.org/obo/UBERON_0001986 denotes endothelium
T216 18030-18036 http://purl.obolibrary.org/obo/UBERON_0001630 denotes muscle
T217 18030-18036 http://purl.obolibrary.org/obo/UBERON_0005090 denotes muscle
T218 18030-18036 http://www.ebi.ac.uk/efo/EFO_0000801 denotes muscle
T219 18030-18036 http://www.ebi.ac.uk/efo/EFO_0001949 denotes muscle
T220 18040-18045 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T221 18106-18111 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T222 18106-18111 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T223 18106-18111 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T224 18106-18111 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T225 18159-18163 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T226 18189-18190 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T227 18284-18285 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T228 18334-18338 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T229 18427-18437 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T230 18517-18522 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T231 18601-18606 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T232 18619-18623 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T233 18722-18730 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T234 18982-18985 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T235 19028-19034 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T236 19055-19063 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T237 19068-19074 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T238 19146-19147 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T239 19208-19213 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T240 19214-19217 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T241 19239-19240 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T242 19302-19312 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T243 19362-19365 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T244 19444-19450 http://purl.obolibrary.org/obo/UBERON_0000948 denotes hearts
T245 19444-19450 http://purl.obolibrary.org/obo/UBERON_0007100 denotes hearts
T246 19444-19450 http://purl.obolibrary.org/obo/UBERON_0015228 denotes hearts
T247 19444-19450 http://www.ebi.ac.uk/efo/EFO_0000815 denotes hearts
T248 19571-19575 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T249 19571-19575 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T250 19651-19652 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T251 19696-19697 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T252 19759-19767 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T253 19776-19780 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T254 20066-20069 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T255 20127-20134 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T256 20222-20223 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T257 20224-20229 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T258 20224-20229 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T259 20224-20229 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T260 20224-20229 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T261 20230-20236 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T262 20237-20244 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T263 20302-20308 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T264 20391-20399 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T265 20484-20492 http://purl.obolibrary.org/obo/CLO_0001658 denotes activate
T266 20554-20556 http://purl.obolibrary.org/obo/CLO_0007074 denotes kB
T267 20554-20556 http://purl.obolibrary.org/obo/CLO_0051988 denotes kB
T268 20557-20566 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T269 20570-20574 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T270 20570-20574 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T271 20575-20585 http://purl.obolibrary.org/obo/CL_0000057 denotes fibroblast
T272 20693-20697 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T273 20693-20697 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T274 20829-20833 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T275 20829-20833 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T276 20884-20885 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T277 21054-21058 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T278 21054-21058 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T279 21114-21124 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T280 21157-21161 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T281 21162-21170 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T282 21185-21186 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T283 21295-21303 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T284 21479-21483 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T285 21479-21483 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T286 21582-21586 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T287 21677-21681 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T288 21677-21681 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T289 21819-21823 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T290 21819-21823 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T291 22015-22023 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T292 22027-22031 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T293 22027-22031 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T294 22076-22084 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T295 22162-22165 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T296 22220-22225 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T297 22323-22329 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T298 22358-22362 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T299 22385-22386 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T300 22502-22512 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T301 22557-22558 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T302 22602-22605 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T303 22650-22651 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T304 22762-22772 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T305 22798-22803 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T306 22804-22810 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T307 22883-22893 http://purl.obolibrary.org/obo/SO_0000418 denotes signalling
T308 22895-22897 http://purl.obolibrary.org/obo/CLO_0054055 denotes 71
T309 22950-22955 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T310 23108-23111 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T311 23273-23279 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T312 23345-23353 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T313 23666-23676 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T314 23823-23827 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T315 23873-23874 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T316 23906-23910 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T317 23967-23972 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T318 24016-24017 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T319 24039-24043 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T320 24173-24174 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T321 24553-24569 http://purl.obolibrary.org/obo/CL_0000746 denotes cardiac myocytes
T322 24646-24654 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T323 24734-24742 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T324 24818-24834 http://purl.obolibrary.org/obo/CL_0000746 denotes cardiac myocytes
T325 24843-24849 http://www.ebi.ac.uk/efo/EFO_0000265 denotes aortic
T326 24859-24878 http://purl.obolibrary.org/obo/CL_0000192 denotes smooth muscle cells
T327 24965-24966 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T328 25085-25095 http://purl.obolibrary.org/obo/SO_0000418 denotes signalling
T329 25104-25105 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T330 25267-25274 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T331 25424-25432 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T332 25489-25497 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T333 25538-25539 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T334 25588-25592 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T335 25740-25741 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T336 25760-25766 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T337 25790-25798 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T338 25827-25828 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T339 25847-25853 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T340 25874-25882 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T341 26173-26177 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T342 26376-26384 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T343 26416-26426 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T344 26468-26472 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T345 26473-26481 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T346 26618-26619 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T347 26797-26800 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T348 26940-26943 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T349 27464-27466 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T350 27467-27469 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T351 27467-27469 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T352 27591-27592 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T353 27625-27627 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T354 27628-27630 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T355 27628-27630 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T356 27759-27763 http://purl.obolibrary.org/obo/CLO_0050507 denotes 2 [2
T357 27813-27823 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T358 27824-27830 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T359 27831-27836 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T360 27897-27907 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T361 27908-27913 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T362 28256-28264 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T363 28275-28285 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T364 28610-28614 http://purl.obolibrary.org/obo/UBERON_0002415 denotes tail
T365 28652-28662 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T366 28748-28749 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T367 28903-28913 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T368 29083-29091 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T369 29246-29252 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T370 29294-29304 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T371 29376-29384 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T372 29393-29397 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T373 29608-29616 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T374 29848-29849 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T375 30108-30121 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T376 30141-30146 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T377 30183-30191 http://purl.obolibrary.org/obo/OBI_0100026 denotes organism
T378 30183-30191 http://purl.obolibrary.org/obo/UBERON_0000468 denotes organism
T379 30243-30251 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T380 30572-30580 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T381 30660-30664 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T382 30660-30664 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T383 30737-30745 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T384 30754-30758 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T385 31112-31116 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T386 31173-31175 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T387 31240-31245 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T388 31240-31245 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T389 31338-31346 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T390 31455-31460 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T391 31545-31553 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T392 31674-31679 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T393 31729-31733 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T394 31734-31743 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membranes
T395 31763-31771 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T396 31805-31809 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T397 31805-31809 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T398 31983-31984 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T399 32039-32048 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs in
T400 32221-32228 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T401 32405-32413 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T402 32975-32983 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T403 33143-33151 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T404 33231-33232 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T405 33270-33273 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T406 33365-33373 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T407 33374-33377 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T408 33406-33409 http://purl.obolibrary.org/obo/CLO_0050884 denotes ten
T409 33525-33533 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T410 33677-33685 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T411 34021-34022 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T412 34198-34202 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T413 34323-34331 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T414 34372-34380 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T415 34457-34467 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T416 34563-34564 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T417 34860-34870 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T418 34874-34885 http://purl.obolibrary.org/obo/CLO_0053065 denotes human cells
T419 34926-34929 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T420 35264-35269 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T421 35270-35276 http://www.ebi.ac.uk/efo/EFO_0000265 denotes aortic
T422 35277-35296 http://purl.obolibrary.org/obo/CL_0000192 denotes smooth muscle cells
T423 35347-35349 http://purl.obolibrary.org/obo/CLO_0007074 denotes kB
T424 35347-35349 http://purl.obolibrary.org/obo/CLO_0051988 denotes kB
T425 35468-35469 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T426 35542-35547 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T427 35542-35547 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T428 35712-35720 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T429 35814-35824 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T430 35903-35904 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T431 35919-35920 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T432 35974-35979 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T433 35974-35979 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T434 36056-36057 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T435 36152-36159 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T436 36246-36247 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T437 36260-36261 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T438 36337-36338 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T439 36376-36377 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T440 36408-36413 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T441 36408-36413 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T442 36430-36435 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T443 36430-36435 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T444 36430-36435 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T445 36430-36435 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T446 36458-36459 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T447 36511-36512 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T448 36616-36617 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T449 36698-36701 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T450 36826-36832 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T451 36967-36975 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T452 37155-37156 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T453 37284-37285 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T454 37316-37317 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T455 37383-37384 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T456 37415-37416 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T457 37472-37475 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T458 37476-37477 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T459 37534-37535 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T460 37631-37639 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T461 37704-37712 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T462 37797-37802 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T463 37797-37802 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T464 37797-37802 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T465 37797-37802 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T466 37804-37811 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidneys
T467 37804-37811 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidneys
T468 37804-37811 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidneys
T469 37813-37818 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T470 37813-37818 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T471 37820-37825 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colon
T472 37827-37842 http://purl.obolibrary.org/obo/UBERON_0002108 denotes small intestine
T473 37844-37848 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T474 37844-37848 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T475 37850-37855 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T476 37850-37855 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T477 37860-37866 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testes
T478 37935-37949 http://purl.obolibrary.org/obo/CL_0000746 denotes cardiomyocytes
T479 37951-37962 http://purl.obolibrary.org/obo/UBERON_0001986 denotes endothelium
T480 37981-37986 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T481 37997-38003 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T482 38004-38009 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T483 38020-38039 http://purl.obolibrary.org/obo/CL_0000192 denotes smooth muscle cells
T484 38055-38067 http://purl.obolibrary.org/obo/CL_0000178 denotes Leydig cells
T485 38142-38152 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T486 38153-38158 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T487 38162-38175 http://purl.obolibrary.org/obo/UBERON_0009773 denotes renal tubules
T488 38177-38181 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T489 38177-38181 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T490 38229-38234 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T491 38281-38291 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T492 38423-38424 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T493 38495-38504 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T494 38723-38733 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T495 39009-39015 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T496 39052-39058 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T497 39242-39248 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T498 39328-39338 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T499 39467-39473 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T500 39491-39492 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T501 39630-39631 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T502 39735-39736 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T503 39765-39773 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T504 39809-39815 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T505 39863-39869 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T506 40054-40060 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T507 40093-40099 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T508 40146-40152 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T509 40179-40180 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T510 40370-40376 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T511 40682-40688 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T512 40770-40771 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T513 40849-40850 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T514 40924-40929 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T515 41022-41029 http://purl.obolibrary.org/obo/UBERON_0003100 denotes females
T516 41062-41067 http://purl.obolibrary.org/obo/UBERON_0003101 denotes males
T517 41062-41067 http://www.ebi.ac.uk/efo/EFO_0000970 denotes males
T518 41243-41249 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T519 41333-41338 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T520 41466-41474 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T521 41571-41578 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T522 41597-41603 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T523 41777-41778 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T524 41833-41839 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T525 41864-41872 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T526 41958-41964 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T527 41958-41964 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T528 41958-41964 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T529 41990-41991 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T530 42080-42081 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T531 42144-42152 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T532 42388-42396 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T533 42468-42469 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T534 42504-42505 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T535 42536-42537 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T536 42689-42695 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T537 42964-42970 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T538 43110-43119 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T539 43211-43221 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T540 43230-43234 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T541 43341-43342 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T542 43431-43432 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T543 43595-43598 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T544 43637-43643 http://purl.obolibrary.org/obo/UBERON_0001630 denotes muscle
T545 43637-43643 http://purl.obolibrary.org/obo/UBERON_0005090 denotes muscle
T546 43637-43643 http://www.ebi.ac.uk/efo/EFO_0000801 denotes muscle
T547 43637-43643 http://www.ebi.ac.uk/efo/EFO_0001949 denotes muscle
T548 43726-43730 http://purl.obolibrary.org/obo/CLO_0053704 denotes IL-8
T549 43887-43891 http://purl.obolibrary.org/obo/CLO_0053704 denotes IL-8
T550 43920-43921 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T551 44132-44141 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T552 44160-44166 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T553 44183-44186 http://purl.obolibrary.org/obo/CLO_0054060 denotes 102
T554 44216-44219 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T555 44330-44333 http://purl.obolibrary.org/obo/CLO_0054060 denotes 102
T556 44354-44365 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood cells
T557 44406-44407 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T558 44493-44497 http://purl.obolibrary.org/obo/CLO_0053704 denotes IL-8
T559 44567-44585 http://purl.obolibrary.org/obo/UBERON_0002012 denotes pulmonary arterial
T560 44567-44585 http://www.ebi.ac.uk/efo/EFO_0001399 denotes pulmonary arterial
T561 44631-44635 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T562 44678-44682 http://purl.obolibrary.org/obo/PR_000001379 denotes IL-2
T563 44696-44700 http://purl.obolibrary.org/obo/CLO_0053704 denotes IL-8
T564 44786-44787 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T565 44815-44825 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T566 44981-44982 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T567 45374-45396 http://purl.obolibrary.org/obo/UBERON_0005409 denotes gastrointestinal tract
T568 45816-45826 http://purl.obolibrary.org/obo/UBERON_0000160 denotes intestinal
T569 45816-45826 http://www.ebi.ac.uk/efo/EFO_0000834 denotes intestinal
T570 46155-46157 http://purl.obolibrary.org/obo/CLO_0001627 denotes AA
T571 46295-46296 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T572 46398-46400 http://purl.obolibrary.org/obo/CLO_0001627 denotes AA
T573 46501-46509 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T574 46530-46540 http://purl.obolibrary.org/obo/UBERON_0000160 denotes intestinal
T575 46530-46540 http://www.ebi.ac.uk/efo/EFO_0000834 denotes intestinal
T576 46573-46578 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T577 46573-46578 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T578 46643-46645 http://purl.obolibrary.org/obo/CLO_0001627 denotes AA
T579 46744-46746 http://purl.obolibrary.org/obo/CLO_0001627 denotes AA
T580 46760-46762 http://purl.obolibrary.org/obo/CLO_0001627 denotes AA
T581 46779-46784 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T582 46825-46827 http://purl.obolibrary.org/obo/CLO_0001627 denotes AA
T583 46897-46899 http://purl.obolibrary.org/obo/CLO_0001627 denotes AA
T584 46908-46909 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T585 46952-46959 http://purl.obolibrary.org/obo/PR_000009054 denotes insulin
T586 46999-47004 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T587 47020-47021 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T588 47066-47074 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T589 47164-47170 http://purl.obolibrary.org/obo/UBERON_0001969 denotes Plasma
T590 47218-47219 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T591 47236-47246 http://purl.obolibrary.org/obo/UBERON_0000160 denotes intestinal
T592 47236-47246 http://www.ebi.ac.uk/efo/EFO_0000834 denotes intestinal
T593 47406-47411 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T594 47406-47411 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T595 47501-47507 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T596 47581-47583 http://purl.obolibrary.org/obo/CLO_0001627 denotes AA
T597 47690-47700 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T598 47730-47742 http://purl.obolibrary.org/obo/UBERON_0001969 denotes blood plasma
T599 47810-47827 http://purl.obolibrary.org/obo/CL_0000115 denotes endothelial cells
T600 47859-47876 http://purl.obolibrary.org/obo/CL_0000115 denotes endothelial cells
T601 47929-47935 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T602 47972-47973 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T603 48112-48122 http://purl.obolibrary.org/obo/CL_0000000 denotes cell types
T604 48133-48139 http://purl.obolibrary.org/obo/UBERON_0001969 denotes Plasma
T605 48198-48202 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T606 48219-48224 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T607 48241-48247 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T608 48266-48271 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T609 48273-48290 http://purl.obolibrary.org/obo/CL_0000115 denotes endothelial cells
T610 48304-48318 http://purl.obolibrary.org/obo/CL_0000746 denotes cardiomyocytes
T611 48544-48554 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T612 48582-48597 http://purl.obolibrary.org/obo/CL_0000786 denotes plasma to cells
T613 48686-48691 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T614 48686-48691 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T615 48714-48724 http://purl.obolibrary.org/obo/SO_0000418 denotes signalling
T616 48730-48731 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T617 48930-48933 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T618 48967-48987 http://purl.obolibrary.org/obo/PR_000036193 denotes amyloid beta-peptide
T619 49128-49131 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T620 49318-49319 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T621 49431-49437 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T622 49652-49655 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T623 49690-49694 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T624 49712-49718 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T625 49750-49753 http://purl.obolibrary.org/obo/CLO_0054060 denotes 102
T626 49769-49775 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T627 49792-49793 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T628 49970-49971 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T629 50249-50252 http://purl.obolibrary.org/obo/CLO_0050884 denotes ten
T630 50329-50330 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T631 50432-50438 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T632 50476-50486 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T633 50621-50627 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T634 50662-50663 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T635 50721-50742 http://purl.obolibrary.org/obo/PR_000036193 denotes amyloid beta-peptides
T636 50805-50808 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T637 50899-50907 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T638 50931-50934 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T639 50945-50946 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T640 51099-51105 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T641 51169-51175 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T642 51242-51252 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T643 51311-51317 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T644 51380-51386 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T645 51731-51732 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T646 51908-51909 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T647 51963-51964 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T648 51989-51995 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T649 52061-52066 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T650 52061-52066 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T651 52244-52260 http://purl.obolibrary.org/obo/CL_0000115 denotes endothelial cell
T652 52316-52334 http://purl.obolibrary.org/obo/UBERON_0002012 denotes pulmonary arteries
T653 52316-52334 http://www.ebi.ac.uk/efo/EFO_0001399 denotes pulmonary arteries
T654 52592-52596 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T655 52592-52596 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T656 52647-52651 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T657 52647-52651 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T658 52661-52666 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T659 52939-52947 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T660 52973-52981 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T661 53148-53149 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T662 53162-53169 http://purl.obolibrary.org/obo/CLO_0001927 denotes bending
T663 53186-53194 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T664 53246-53254 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T665 53370-53371 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T666 53538-53539 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T667 53555-53563 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T668 53662-53670 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T669 53749-53754 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T670 53867-53872 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T671 53894-53898 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T672 53910-53911 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T673 54089-54095 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T674 54096-54104 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T675 54172-54180 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T676 54342-54350 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T677 54414-54422 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T678 54684-54687 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T679 54845-54846 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T680 54868-54873 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T681 54921-54926 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T682 54958-54959 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T683 55032-55033 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T684 55042-55043 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T685 55078-55079 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T686 55139-55142 http://purl.obolibrary.org/obo/CLO_0053001 denotes 114
T687 55145-55152 http://purl.obolibrary.org/obo/UBERON_0000473 denotes Testing
T688 55211-55212 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T689 55263-55268 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T690 55270-55272 http://purl.obolibrary.org/obo/CLO_0008812 denotes rh
T691 55287-55297 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T692 55325-55328 http://purl.obolibrary.org/obo/CLO_0053001 denotes 114
T693 55342-55343 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T694 55453-55454 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T695 55606-55607 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T696 55676-55679 http://purl.obolibrary.org/obo/CLO_0053001 denotes 114
T697 55721-55722 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T698 55755-55763 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T699 55785-55793 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T700 55876-55877 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T701 55939-55940 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T702 55988-56005 http://purl.obolibrary.org/obo/CL_0000842 denotes mononuclear cells
T703 56043-56046 http://purl.obolibrary.org/obo/CLO_0053001 denotes 114
T704 56049-56050 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T705 56140-56141 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T706 56143-56146 http://purl.obolibrary.org/obo/CLO_0053001 denotes 114
T707 56188-56196 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T708 56380-56381 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T709 56433-56441 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T710 56451-56452 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T711 56596-56604 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T712 56834-56838 http://purl.obolibrary.org/obo/CLO_0050171 denotes M–10
T713 56928-56929 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T714 56997-56998 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T715 57125-57133 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T716 57161-57169 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T717 57181-57189 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T718 57239-57247 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T719 57288-57293 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T720 57294-57300 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T721 57358-57361 http://purl.obolibrary.org/obo/CLO_0001046 denotes 116
T722 57472-57477 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T723 57683-57691 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T724 57720-57721 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T725 57822-57827 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T726 57822-57827 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T727 57935-57938 http://purl.obolibrary.org/obo/CLO_0053799 denotes 4-5
T728 57962-57967 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T729 57962-57967 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T730 58057-58061 http://purl.obolibrary.org/obo/UBERON_0003101 denotes male
T731 58057-58061 http://www.ebi.ac.uk/efo/EFO_0000970 denotes male
T732 58069-58071 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T733 58203-58211 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T734 58321-58326 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T735 58321-58326 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T736 58418-58421 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T737 58487-58488 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T738 58518-58519 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T739 58714-58715 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T740 58760-58761 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T741 58848-58849 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T742 58859-58866 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T743 58897-58898 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T744 59074-59075 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T745 59166-59167 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T746 59168-59173 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T747 59201-59205 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T748 59201-59205 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T749 59220-59223 http://purl.obolibrary.org/obo/CLO_0001053 denotes 121
T750 59319-59324 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T751 59475-59482 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals
T752 59566-59571 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T753 59652-59653 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T754 59717-59721 http://purl.obolibrary.org/obo/UBERON_0003101 denotes male
T755 59717-59721 http://www.ebi.ac.uk/efo/EFO_0000970 denotes male
T756 59782-59785 http://purl.obolibrary.org/obo/CLO_0002096 denotes C16
T757 59839-59840 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T758 59941-59949 http://purl.obolibrary.org/obo/UBERON_0001637 denotes arterial
T759 59941-59949 http://www.ebi.ac.uk/efo/EFO_0000814 denotes arterial
T760 60066-60068 http://purl.obolibrary.org/obo/CLO_0001407 denotes 52
T761 60082-60083 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T762 60311-60319 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T763 60337-60342 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T764 60337-60342 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T765 60337-60342 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T766 60337-60342 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T767 60344-60348 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T768 60344-60348 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T769 60350-60355 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T770 60350-60355 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T771 60357-60362 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colon
T772 60380-60386 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T773 60411-60416 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T774 60411-60416 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T775 60421-60438 http://purl.obolibrary.org/obo/CL_0000115 denotes endothelial cells
T776 60524-60532 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T777 60536-60537 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T778 60538-60543 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T779 60962-60963 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T780 60981-60984 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T781 61023-61031 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T782 61076-61079 http://purl.obolibrary.org/obo/CLO_0054060 denotes 102
T783 61159-61165 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T784 61301-61307 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T785 61336-61337 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T786 61377-61383 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T787 61492-61501 http://purl.obolibrary.org/obo/OBI_0100026 denotes organisms
T788 61492-61501 http://purl.obolibrary.org/obo/UBERON_0000468 denotes organisms
T789 61845-61855 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T790 61880-61883 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T791 61950-61953 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T792 62078-62081 http://purl.obolibrary.org/obo/CLO_0054060 denotes 102
T793 62137-62138 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T794 62341-62346 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T795 62341-62346 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T796 62359-62360 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T797 62651-62656 http://purl.obolibrary.org/obo/GO_0005623 denotes Cells
T798 62783-62789 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T799 62846-62856 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T800 63106-63111 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T801 63199-63205 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T802 63206-63214 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T803 63306-63311 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T804 63541-63544 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T805 63634-63643 http://purl.obolibrary.org/obo/GO_0005764 denotes lysosomes
T806 63880-63883 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T807 63922-63930 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T808 63954-63964 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T809 64002-64012 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T810 64050-64068 http://purl.obolibrary.org/obo/GO_0030141 denotes secretory granules
T811 64069-64072 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T812 64120-64128 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T813 64305-64306 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T814 64562-64566 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T815 64595-64596 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T816 64702-64703 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T817 65103-65106 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T818 65151-65157 http://purl.obolibrary.org/obo/UBERON_0001637 denotes artery
T819 65151-65157 http://www.ebi.ac.uk/efo/EFO_0000814 denotes artery
T820 65268-65269 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T821 65372-65377 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T822 65624-65625 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T823 65676-65679 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T33721 65697-65703 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T825 65713-65716 http://purl.obolibrary.org/obo/CLO_0001046 denotes 116
T826 65755-65756 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T827 65791-65792 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T828 65852-65858 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T829 65866-65869 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T830 65894-65895 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T831 65902-65904 http://purl.obolibrary.org/obo/CLO_0001627 denotes AA
T832 65908-65909 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T833 65922-65929 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T834 65968-65971 http://purl.obolibrary.org/obo/CLO_0001046 denotes 116
T835 66004-66006 http://purl.obolibrary.org/obo/CLO_0001627 denotes AA
T836 66112-66113 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T837 66120-66122 http://purl.obolibrary.org/obo/CLO_0001627 denotes AA
T838 66126-66127 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T839 66140-66147 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T840 66258-66266 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T841 66490-66491 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T842 66692-66695 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T843 66696-66697 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T844 66779-66780 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T845 66835-66843 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T846 66878-66886 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T847 66968-66971 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T848 67013-67014 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T849 67060-67061 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T850 67163-67171 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T851 67299-67302 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T852 67432-67435 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T853 67549-67557 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T854 67592-67595 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T855 67596-67597 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T856 67608-67614 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T857 67689-67692 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T858 67814-67815 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T859 67967-67977 http://purl.obolibrary.org/obo/UBERON_0000160 denotes intestinal
T860 67967-67977 http://www.ebi.ac.uk/efo/EFO_0000834 denotes intestinal
T861 68120-68121 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T862 68219-68222 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T863 68249-68257 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T864 68404-68405 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T865 68556-68564 http://purl.obolibrary.org/obo/UBERON_0002553 denotes cavities
T866 68605-68606 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T867 68735-68738 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T868 68777-68782 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T869 68854-68857 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T870 68950-68955 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T871 69298-69299 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T872 69323-69324 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T873 69345-69350 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T874 69356-69359 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T875 69475-69481 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T876 69583-69584 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T877 69632-69635 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T878 69792-69796 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T879 69927-69935 http://purl.obolibrary.org/obo/CLO_0001658 denotes Activity
T880 70107-70111 http://purl.obolibrary.org/obo/UBERON_0003101 denotes male
T881 70107-70111 http://www.ebi.ac.uk/efo/EFO_0000970 denotes male
T882 70391-70393 http://purl.obolibrary.org/obo/CLO_0053794 denotes 41
T883 70513-70515 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T884 70582-70590 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T885 70594-70600 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T886 70660-70661 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T887 70690-70691 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T888 70779-70783 http://purl.obolibrary.org/obo/UBERON_0003101 denotes male
T889 70779-70783 http://www.ebi.ac.uk/efo/EFO_0000970 denotes male
T890 70861-70869 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T891 71002-71010 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T892 71233-71234 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T893 71316-71324 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T894 71555-71563 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T895 71679-71687 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T896 71740-71746 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T897 71989-71999 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T898 72072-72078 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T899 72297-72305 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T900 72333-72338 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T901 72339-72355 http://purl.obolibrary.org/obo/UBERON_0002012 denotes pulmonary artery
T902 72339-72355 http://www.ebi.ac.uk/efo/EFO_0001399 denotes pulmonary artery
T903 72356-72375 http://purl.obolibrary.org/obo/CL_0000192 denotes smooth muscle cells
T904 72570-72571 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T905 72600-72608 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T906 72697-72705 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T907 73044-73045 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T908 73255-73256 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T909 73834-73835 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T910 74191-74195 http://purl.obolibrary.org/obo/UBERON_0001456 denotes face
T911 74238-74239 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T912 74470-74471 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T913 74632-74639 http://purl.obolibrary.org/obo/PR_000009054 denotes insulin
T914 74712-74720 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T915 74832-74838 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T916 74866-74872 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T917 75209-75215 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T918 75233-75239 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T919 75240-75245 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T920 75478-75483 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T921 75478-75483 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T922 75478-75483 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T923 75478-75483 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T924 75532-75533 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T925 75575-75581 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T926 75587-75595 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T927 75676-75680 http://purl.obolibrary.org/obo/UBERON_0003101 denotes male
T928 75676-75680 http://www.ebi.ac.uk/efo/EFO_0000970 denotes male
T929 75772-75773 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T930 75818-75826 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T931 75942-75943 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T932 76046-76054 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T933 76445-76454 http://www.ebi.ac.uk/efo/EFO_0000876 denotes extremely
T934 76641-76643 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T935 76679-76680 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T936 76742-76748 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T937 76742-76748 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T938 76742-76748 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T939 76774-76775 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T940 76821-76822 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T941 76864-76872 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T942 76986-76991 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T943 76986-76991 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T944 77034-77040 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T945 77034-77040 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T946 77034-77040 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T947 77130-77138 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T948 77208-77209 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T949 77535-77536 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T950 77615-77620 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T951 77615-77620 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T952 77708-77712 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T953 77751-77759 http://purl.obolibrary.org/obo/OBI_0100026 denotes organism
T954 77751-77759 http://purl.obolibrary.org/obo/UBERON_0000468 denotes organism
T955 77966-77971 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T956 77986-77990 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T957 78120-78124 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T958 78342-78351 http://purl.obolibrary.org/obo/UBERON_0007651 denotes junctions
T959 78512-78516 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T960 78552-78555 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T961 78622-78623 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T962 78742-78745 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T963 78800-78801 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T964 78879-78885 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T965 79193-79196 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T966 79227-79231 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T967 79351-79357 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T968 79439-79444 http://purl.obolibrary.org/obo/UBERON_0003101 denotes males
T969 79439-79444 http://www.ebi.ac.uk/efo/EFO_0000970 denotes males
T970 79453-79460 http://purl.obolibrary.org/obo/UBERON_0003100 denotes females
T971 79507-79514 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airways
T972 79525-79531 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T973 79583-79590 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airways
T974 79594-79601 http://purl.obolibrary.org/obo/UBERON_0003100 denotes females
T975 79660-79665 http://purl.obolibrary.org/obo/UBERON_0003101 denotes males
T976 79660-79665 http://www.ebi.ac.uk/efo/EFO_0000970 denotes males
T977 79980-79990 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T978 80024-80034 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T979 80075-80080 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T980 80075-80080 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T981 80184-80185 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T982 80332-80337 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T983 80400-80406 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T984 80569-80570 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T985 80593-80603 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T986 80669-80670 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T987 80725-80728 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T988 81024-81029 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T989 81141-81148 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T990 81284-81293 http://purl.obolibrary.org/obo/OBI_0100026 denotes organisms
T991 81284-81293 http://purl.obolibrary.org/obo/UBERON_0000468 denotes organisms
T992 81344-81352 http://purl.obolibrary.org/obo/CLO_0001658 denotes Activity
T993 81387-81388 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T994 81563-81569 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T995 81656-81659 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T996 81677-81678 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T997 81787-81790 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T998 82032-82040 http://purl.obolibrary.org/obo/NCBITaxon_9443 denotes primates
T999 82073-82074 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1000 82123-82130 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals
T1001 82186-82187 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1002 82209-82213 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T1003 82209-82213 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T1004 82293-82294 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1005 82460-82468 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1006 82622-82623 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1007 82778-82783 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T1008 82793-82796 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T1009 82797-82804 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T1010 83223-83233 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T1011 83504-83505 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1012 83691-83696 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1013 83712-83717 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T1014 83732-83737 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T1015 83773-83783 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T1016 83792-83796 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T1017 83877-83882 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T1018 83971-83981 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T1019 84243-84248 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T1020 84243-84248 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T1021 84312-84317 http://purl.obolibrary.org/obo/UBERON_0003103 denotes Organ
T1022 84390-84392 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T1023 84527-84529 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T1024 84722-84730 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1025 84789-84794 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T1026 84789-84794 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T1027 84893-84901 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1028 84965-84971 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T1029 85052-85058 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T1030 85060-85063 http://purl.obolibrary.org/obo/CLO_0001046 denotes 116
T1031 85129-85137 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1032 85226-85227 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1033 85255-85263 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1034 85297-85298 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T1035 85470-85475 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T1036 85470-85475 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T1037 85632-85637 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1038 85645-85651 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T1039 85871-85879 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1040 85887-85893 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T1041 85908-85909 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1042 85954-85959 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T1043 86006-86014 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T1044 86018-86024 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T1045 86084-86092 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1046 86096-86102 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T1047 86116-86117 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1048 86160-86161 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1049 86194-86195 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1050 86385-86393 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1051 86446-86449 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T1052 86469-86475 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T1053 86618-86620 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1054 86635-86637 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1055 86698-86702 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T1056 86698-86702 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T1057 86739-86742 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T1058 86743-86749 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T1059 86971-86979 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T1060 86983-86989 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T1061 87030-87031 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1062 87060-87078 http://purl.obolibrary.org/obo/UBERON_0002012 denotes pulmonary arterial
T1063 87060-87078 http://www.ebi.ac.uk/efo/EFO_0001399 denotes pulmonary arterial
T1064 87290-87294 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T1065 87290-87294 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T1066 87464-87469 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T1067 87502-87507 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T1068 87518-87523 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T1069 87598-87604 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T1070 87641-87642 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1071 87665-87671 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T1072 87706-87710 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T1073 87706-87710 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T1074 87737-87745 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1075 87804-87807 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T1076 87874-87879 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T1077 87983-87989 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T1078 88291-88297 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T1079 88437-88439 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1080 88496-88498 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1081 88520-88521 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1082 88547-88555 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1083 88684-88686 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T1084 88690-88692 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1085 88799-88805 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T1086 88832-88840 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T1087 89020-89027 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T1088 89058-89065 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T1089 89125-89130 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T1090 89125-89130 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T1091 89144-89145 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1092 89202-89208 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T1093 89327-89335 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1094 89343-89349 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T1095 89367-89374 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T1096 89462-89470 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T1097 89571-89579 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T1098 89642-89644 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1099 89645-89650 http://purl.obolibrary.org/obo/CLO_0007735 denotes mL, 1
T1100 89654-89656 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1101 89657-89663 http://purl.obolibrary.org/obo/CLO_0007736 denotes mL, <2
T1102 89664-89666 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1103 89674-89676 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1104 89688-89690 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1105 89776-89784 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T1106 89790-89792 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T1107 89796-89798 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1108 89811-89813 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1109 89814-89821 http://purl.obolibrary.org/obo/CLO_0007736 denotes mL, < 2
T1110 89822-89824 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1111 89833-89835 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1112 89847-89849 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1113 89929-89937 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1114 89961-89968 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T1115 90079-90084 http://purl.obolibrary.org/obo/UBERON_0003101 denotes males
T1116 90079-90084 http://www.ebi.ac.uk/efo/EFO_0000970 denotes males
T1117 90124-90126 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1118 90138-90140 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1119 90526-90534 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T1120 90769-90771 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1121 90803-90805 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1122 90827-90828 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T1123 90969-90971 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1124 91089-91096 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T1125 91343-91345 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1126 91395-91397 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1127 91583-91591 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T1128 91708-91710 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1129 91822-91830 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1130 91853-91859 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T1131 92265-92271 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T1132 92285-92290 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T1133 92390-92392 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1134 92439-92447 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1135 92458-92464 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T1136 92566-92567 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1137 92599-92607 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1138 92969-92971 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T1139 93016-93024 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1140 93088-93098 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T1141 93108-93112 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T1142 93150-93160 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T1143 93228-93234 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T1144 93249-93250 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1145 93447-93455 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1146 93486-93496 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T1147 93505-93509 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T1148 93585-93590 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T1149 93600-93606 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T1150 93780-93788 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T1151 93831-93839 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1152 93863-93871 http://purl.obolibrary.org/obo/UBERON_0001637 denotes arterial
T1153 93863-93871 http://www.ebi.ac.uk/efo/EFO_0000814 denotes arterial
T1154 94052-94054 http://purl.obolibrary.org/obo/CLO_0054055 denotes 71
T1155 94087-94088 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1156 94246-94247 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1157 94298-94306 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T1158 94323-94329 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T1159 94362-94368 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T1160 94438-94444 http://purl.obolibrary.org/obo/UBERON_0001637 denotes artery
T1161 94438-94444 http://www.ebi.ac.uk/efo/EFO_0000814 denotes artery
T1162 94478-94479 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1163 94543-94544 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1164 94622-94627 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T1165 94622-94627 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T1166 94727-94734 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T1167 94826-94832 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T1168 94853-94860 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T1169 95092-95093 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1170 95178-95184 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T1171 95194-95196 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T1172 95729-95734 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T1173 95753-95761 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T1174 95790-95795 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T1175 95801-95807 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T1176 95831-95832 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T41156 95918-95923 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T1178 95950-95955 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T1179 95960-95965 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T1180 95971-95979 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1181 95986-95991 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T1182 96021-96026 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T1183 96081-96086 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T1184 96103-96106 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T1185 96157-96162 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T1186 96199-96202 http://purl.obolibrary.org/obo/CLO_0002096 denotes C16
T1187 96260-96264 http://purl.obolibrary.org/obo/UBERON_0001456 denotes face
T1188 96322-96324 http://purl.obolibrary.org/obo/CLO_0050475 denotes my
T1189 96355-96358 http://purl.obolibrary.org/obo/CLO_0002096 denotes C16
T1190 96407-96410 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T1191 96416-96422 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T1192 96434-96440 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T1193 96444-96445 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1194 96568-96575 http://purl.obolibrary.org/obo/CLO_0009985 denotes focused
T1195 96576-96578 http://purl.obolibrary.org/obo/CLO_0050475 denotes my
T1196 96606-96611 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T1197 96711-96716 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T1198 96795-96796 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1199 97259-97262 http://purl.obolibrary.org/obo/CLO_0002096 denotes C16
T1200 97323-97326 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T1201 97369-97377 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1202 97461-97466 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T1203 97494-97499 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T1204 97505-97513 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1205 97677-97685 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1206 97740-97742 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T1207 97879-97889 http://purl.obolibrary.org/obo/CLO_0001658 denotes activators
T1208 97914-97924 http://purl.obolibrary.org/obo/CLO_0001658 denotes activating
T1209 97983-97991 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1210 98054-98055 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1211 98082-98088 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T1212 98234-98240 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T1213 98257-98258 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1214 98302-98306 http://purl.obolibrary.org/obo/CLO_0002096 denotes C-16
T1215 98341-98351 http://purl.obolibrary.org/obo/CLO_0001658 denotes activating
T1216 98415-98416 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1217 98456-98457 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1218 98507-98508 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1219 98536-98537 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1220 98545-98552 http://purl.obolibrary.org/obo/PR_000009054 denotes insulin
T1221 98594-98595 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T1222 98711-98721 http://purl.obolibrary.org/obo/CLO_0001658 denotes activating
T1223 98798-98799 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1224 98825-98826 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1225 98846-98847 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T15 322-328 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T16 350-365 Chemical denotes glucocorticoids http://purl.obolibrary.org/obo/CHEBI_24261
T17 380-391 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T18 397-407 Chemical denotes macrolides http://purl.obolibrary.org/obo/CHEBI_25106
T19 893-902 Chemical denotes biomarker http://purl.obolibrary.org/obo/CHEBI_59163
T20 1109-1111 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T22 1116-1118 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T24 1122-1124 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T26 1128-1130 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T28 2052-2068 Chemical denotes antihypertensive http://purl.obolibrary.org/obo/CHEBI_35674
T29 2944-2955 Chemical denotes Angiotensin http://purl.obolibrary.org/obo/CHEBI_2719
T30 3030-3037 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T31 3326-3333 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T32 3370-3377 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T33 3747-3754 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T34 4013-4020 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T35 4042-4044 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T37 4370-4377 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T38 4402-4409 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T39 4504-4511 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T40 4883-4890 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T41 5441-5452 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T42 5550-5557 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T43 5644-5651 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T44 5796-5805 Chemical denotes biomarker http://purl.obolibrary.org/obo/CHEBI_59163
T45 6625-6632 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T46 6852-6859 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T47 7042-7049 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T48 7213-7221 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T49 7309-7322 Chemical denotes glycoproteins http://purl.obolibrary.org/obo/CHEBI_17089
T50 7394-7396 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T51 7398-7405 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T52 7466-7474 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T53 7535-7537 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T54 7770-7782 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T55 8044-8046 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T56 8490-8500 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T57 8490-8495 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T58 8496-8500 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T59 8567-8574 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T60 8645-8652 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T61 8834-8842 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T62 9005-9015 Chemical denotes ferredoxin http://purl.obolibrary.org/obo/CHEBI_5017
T63 9214-9225 Chemical denotes amino acids http://purl.obolibrary.org/obo/CHEBI_33709
T64 9214-9219 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T65 9220-9225 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T66 9380-9382 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T67 9791-9793 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T68 9826-9833 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T69 10107-10114 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T70 10319-10327 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T71 12207-12215 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T72 12277-12284 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T73 12821-12828 Chemical denotes Pathway http://purl.obolibrary.org/obo/CHEBI_34922
T74 12863-12867 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T76 12939-12950 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T77 12959-12962 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T78 12980-12991 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T79 12993-12996 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T80 13004-13006 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T81 13012-13015 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T82 13026-13029 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T83 13079-13086 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T84 13108-13111 Chemical denotes Arg http://purl.obolibrary.org/obo/CHEBI_16467|http://purl.obolibrary.org/obo/CHEBI_29952
T86 13115-13125 Chemical denotes bradykinin http://purl.obolibrary.org/obo/CHEBI_3165
T87 13166-13169 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T88 13180-13183 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T89 13190-13198 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T90 13228-13231 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T91 13232-13234 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T92 13235-13238 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T93 13239-13241 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T94 13436-13448 Chemical denotes nitric oxide http://purl.obolibrary.org/obo/CHEBI_16480
T95 13443-13448 Chemical denotes oxide http://purl.obolibrary.org/obo/CHEBI_25741|http://purl.obolibrary.org/obo/CHEBI_29356
T97 13756-13759 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T98 13760-13762 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T99 13813-13824 Chemical denotes aldosterone http://purl.obolibrary.org/obo/CHEBI_27584|http://purl.obolibrary.org/obo/CHEBI_30834
T101 14111-14121 Chemical denotes antagonist http://purl.obolibrary.org/obo/CHEBI_48706
T102 14303-14306 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T103 14621-14624 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T104 14625-14627 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T105 14702-14705 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T106 14818-14821 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T107 15664-15667 Chemical denotes C16 http://purl.obolibrary.org/obo/CHEBI_15756
T108 15689-15703 Chemical denotes ACE2 inhibitor http://purl.obolibrary.org/obo/CHEBI_147289
T109 15694-15703 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T110 16083-16086 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T111 16087-16089 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T112 16366-16369 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T113 16520-16530 Chemical denotes antagonist http://purl.obolibrary.org/obo/CHEBI_48706
T114 16617-16620 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T115 16621-16623 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T116 16902-16910 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T117 17221-17228 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T118 17361-17368 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T119 17400-17407 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T120 17466-17468 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T122 17790-17793 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T123 17817-17824 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T124 17894-17897 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T125 17898-17900 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T126 18171-18174 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T127 18346-18349 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T128 18446-18449 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T129 18489-18492 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T130 18493-18495 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T131 19075-19078 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T132 19079-19081 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T133 19405-19408 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T134 19526-19529 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T135 19557-19560 Chemical denotes CO2 http://purl.obolibrary.org/obo/CHEBI_16526
T136 19788-19791 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T137 19835-19838 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T138 19904-19907 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T139 19908-19910 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T140 19912-19915 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T141 19923-19926 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T142 19956-19966 Chemical denotes metabolite http://purl.obolibrary.org/obo/CHEBI_25212
T143 19968-19971 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T144 20012-20015 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T145 20031-20034 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T146 20056-20059 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T147 20108-20134 Chemical denotes atrial natriuretic peptide http://purl.obolibrary.org/obo/CHEBI_80233
T148 20127-20134 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T149 20209-20212 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T150 20237-20244 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T151 20354-20357 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T152 20457-20460 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T153 20551-20553 Chemical denotes NF http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224
T156 20637-20640 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T157 20803-20805 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T159 21091-21094 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T160 21497-21501 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T161 21530-21533 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T162 21534-21536 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T163 21875-21878 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T164 21879-21881 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T165 21886-21889 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T166 21901-21904 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T167 21905-21907 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T168 22126-22129 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T169 22152-22155 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T170 22285-22288 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T171 22584-22587 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T172 22627-22629 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T174 22692-22694 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T176 22779-22781 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T178 22847-22854 Chemical denotes agonist http://purl.obolibrary.org/obo/CHEBI_48705
T179 22870-22882 Chemical denotes nitric oxide http://purl.obolibrary.org/obo/CHEBI_16480
T180 22877-22882 Chemical denotes oxide http://purl.obolibrary.org/obo/CHEBI_25741|http://purl.obolibrary.org/obo/CHEBI_29356
T182 22910-22912 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T184 23102-23104 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T186 23144-23151 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T187 23368-23370 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T189 23386-23389 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T190 23464-23466 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T192 23651-23654 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T193 23681-23683 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T195 23835-23838 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T196 24118-24121 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T197 24128-24131 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T198 24132-24134 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T199 24263-24277 Chemical denotes ACE inhibitors http://purl.obolibrary.org/obo/CHEBI_35457
T200 24267-24277 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T201 24279-24284 Chemical denotes ACEIs http://purl.obolibrary.org/obo/CHEBI_35457
T202 24292-24295 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T203 24296-24298 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T204 24494-24497 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T205 24507-24510 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T206 24511-24513 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T207 24599-24602 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T208 24603-24605 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T209 24697-24700 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T210 24701-24703 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T211 24880-24883 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T212 24904-24907 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T213 24908-24910 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T214 24982-24992 Chemical denotes antagonist http://purl.obolibrary.org/obo/CHEBI_48706
T215 25001-25004 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T216 25049-25052 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T217 25073-25076 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T218 25077-25079 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T219 25166-25169 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T220 25188-25193 Chemical denotes ACEIs http://purl.obolibrary.org/obo/CHEBI_35457
T221 25216-25219 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T222 25220-25222 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T223 25263-25266 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T224 25267-25274 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T225 25296-25299 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T226 25300-25302 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T227 25374-25377 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T228 25433-25440 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T229 25600-25603 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T230 25711-25714 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T231 25715-25717 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T232 25803-25806 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T233 26060-26063 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T234 26064-26066 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T235 26080-26090 Chemical denotes antagonist http://purl.obolibrary.org/obo/CHEBI_48706
T236 26091-26094 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T237 26185-26188 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T238 26247-26250 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T239 26257-26260 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T240 26261-26263 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T241 26386-26389 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T242 26668-26671 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T243 26923-26930 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T244 27467-27469 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T245 27534-27546 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T246 27628-27630 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T247 27707-27709 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T249 27967-27969 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T251 28093-28095 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T253 28200-28202 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T255 28859-28866 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T256 29005-29007 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T258 29411-29422 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T259 29506-29509 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T260 29513-29516 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T261 29517-29519 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T262 29521-29524 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T263 29532-29535 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T264 29543-29546 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T265 29570-29580 Chemical denotes metabolite http://purl.obolibrary.org/obo/CHEBI_25212
T266 29581-29591 Chemical denotes bradykinin http://purl.obolibrary.org/obo/CHEBI_3165
T267 29736-29739 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T268 29740-29742 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T269 29837-29840 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T270 29841-29843 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T271 29877-29880 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T272 29903-29906 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T273 29979-29981 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T275 30215-30218 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T276 30272-30274 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T278 30383-30386 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T279 30484-30487 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T280 30488-30490 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T281 30527-30530 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T282 30531-30533 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T283 30601-30604 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T284 30766-30769 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T285 30837-30840 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T286 30853-30856 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T287 30857-30859 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T288 30952-30955 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T289 31124-31127 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T290 32189-32192 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T291 32200-32203 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T292 32204-32206 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T293 32211-32214 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T294 32221-32228 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T295 32333-32336 Chemical denotes Arg http://purl.obolibrary.org/obo/CHEBI_16467|http://purl.obolibrary.org/obo/CHEBI_29952
T297 32340-32350 Chemical denotes bradykinin http://purl.obolibrary.org/obo/CHEBI_3165
T298 32363-32373 Chemical denotes bradykinin http://purl.obolibrary.org/obo/CHEBI_3165
T299 32405-32413 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T300 32534-32537 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T301 32783-32786 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T302 32924-32927 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T303 33171-33177 Chemical denotes serine http://purl.obolibrary.org/obo/CHEBI_17822
T304 33251-33269 Chemical denotes protease inhibitor http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258
T306 33260-33269 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T307 33730-33733 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T308 34006-34020 Chemical denotes apolipoprotein http://purl.obolibrary.org/obo/CHEBI_39015
T309 34054-34065 Chemical denotes polypeptide http://purl.obolibrary.org/obo/CHEBI_15841
T310 34210-34213 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T311 34225-34235 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T312 34243-34246 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T313 34711-34721 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T314 34749-34752 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T315 34770-34773 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T316 34802-34813 Chemical denotes antagonists http://purl.obolibrary.org/obo/CHEBI_48706
T317 34830-34833 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T318 35049-35052 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T319 35075-35078 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T320 35152-35162 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T321 35169-35180 Chemical denotes antagonists http://purl.obolibrary.org/obo/CHEBI_48706
T322 35330-35335 Chemical denotes NADPH http://purl.obolibrary.org/obo/CHEBI_16474|http://purl.obolibrary.org/obo/CHEBI_57783
T324 35344-35346 Chemical denotes NF http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224
T327 35387-35390 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T328 35391-35393 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T329 35418-35421 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T330 35631-35634 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T331 35635-35637 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T332 35749-35752 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T333 35753-35755 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T334 35795-35798 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T335 36001-36008 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T336 36082-36085 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T337 36086-36088 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T338 36221-36224 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T339 36225-36227 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T340 36266-36270 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T341 36686-36697 Chemical denotes antagonists http://purl.obolibrary.org/obo/CHEBI_48706
T342 36926-36937 Chemical denotes antagonists http://purl.obolibrary.org/obo/CHEBI_48706
T343 37040-37046 Chemical denotes Action http://purl.obolibrary.org/obo/CHEBI_5133
T344 37075-37078 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T345 37079-37086 Chemical denotes Pathway http://purl.obolibrary.org/obo/CHEBI_34922
T346 37201-37205 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T348 37336-37346 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T349 37336-37341 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T350 37342-37346 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T351 37428-37437 Chemical denotes dipeptide http://purl.obolibrary.org/obo/CHEBI_46761
T352 37522-37529 Chemical denotes proline http://purl.obolibrary.org/obo/CHEBI_17203|http://purl.obolibrary.org/obo/CHEBI_26271
T354 37557-37575 Chemical denotes C-terminal residue http://purl.obolibrary.org/obo/CHEBI_33711
T355 37612-37615 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T356 37620-37630 Chemical denotes bradykinin http://purl.obolibrary.org/obo/CHEBI_3165
T357 37631-37639 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T358 37704-37712 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T359 37739-37748 Chemical denotes Apelin-13 http://purl.obolibrary.org/obo/CHEBI_80131
T360 37978-37980 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T361 38253-38256 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T362 38425-38429 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T364 38471-38475 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T366 38486-38490 Chemical denotes EDTA http://purl.obolibrary.org/obo/CHEBI_42191|http://purl.obolibrary.org/obo/CHEBI_64755
T368 38531-38539 Chemical denotes chloride http://purl.obolibrary.org/obo/CHEBI_17996
T369 38543-38551 Chemical denotes fluoride http://purl.obolibrary.org/obo/CHEBI_17051
T370 38552-38558 Chemical denotes anions http://purl.obolibrary.org/obo/CHEBI_22563
T371 38563-38574 Chemical denotes zinc cation http://purl.obolibrary.org/obo/CHEBI_29105|http://purl.obolibrary.org/obo/CHEBI_63056
T373 38563-38567 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T375 38568-38574 Chemical denotes cation http://purl.obolibrary.org/obo/CHEBI_36916
T376 38610-38618 Chemical denotes chloride http://purl.obolibrary.org/obo/CHEBI_17996
T377 38624-38628 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T379 38708-38713 Chemical denotes anion http://purl.obolibrary.org/obo/CHEBI_22563
T380 38718-38722 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T382 38799-38807 Chemical denotes chloride http://purl.obolibrary.org/obo/CHEBI_17996
T383 38808-38812 Chemical denotes ions http://purl.obolibrary.org/obo/CHEBI_24870
T384 38823-38826 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T385 38871-38874 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T386 38875-38877 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T387 38882-38885 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T388 38907-38910 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T389 38911-38913 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T390 38948-38956 Chemical denotes chloride http://purl.obolibrary.org/obo/CHEBI_17996
T391 39089-39097 Chemical denotes chloride http://purl.obolibrary.org/obo/CHEBI_17996
T392 39249-39253 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T394 39459-39463 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T396 39493-39500 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T397 39801-39805 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T399 39870-39874 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T401 39964-39968 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T403 40115-40119 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T405 40153-40157 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T407 40302-40306 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T409 40355-40359 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T411 40438-40442 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T413 40496-40500 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T415 40523-40527 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T417 40575-40579 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T419 40689-40693 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T421 40742-40746 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T423 40797-40801 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T425 40902-40906 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T427 40990-40994 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T429 41089-41093 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T431 41165-41169 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T433 41186-41190 Chemical denotes ions http://purl.obolibrary.org/obo/CHEBI_24870
T434 41199-41203 Chemical denotes iron http://purl.obolibrary.org/obo/CHEBI_18248
T435 41250-41254 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T437 41316-41320 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T439 41406-41410 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T441 41567-41570 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T442 41571-41578 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T443 41860-41863 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T444 42123-42127 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T446 42252-42256 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T448 42320-42324 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T450 42482-42485 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T451 42580-42583 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T452 42877-42882 Chemical denotes ZnCl2 http://purl.obolibrary.org/obo/CHEBI_49976
T453 42883-42886 Chemical denotes ZnO http://purl.obolibrary.org/obo/CHEBI_36560
T454 42887-42903 Chemical denotes hexachloroethane http://purl.obolibrary.org/obo/CHEBI_39227
T455 42981-42985 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T457 43146-43154 Chemical denotes chloride http://purl.obolibrary.org/obo/CHEBI_17996
T458 43159-43168 Chemical denotes zinc ions http://purl.obolibrary.org/obo/CHEBI_27365
T459 43159-43163 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T461 43164-43168 Chemical denotes ions http://purl.obolibrary.org/obo/CHEBI_24870
T462 43242-43245 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T463 43418-43422 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T465 43713-43715 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T467 43720-43722 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T469 43726-43728 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T471 43878-43880 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T473 43887-43889 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T475 44050-44054 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T477 44480-44482 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T479 44487-44489 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T481 44493-44495 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T483 44540-44542 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T485 44600-44603 Chemical denotes PAH http://purl.obolibrary.org/obo/CHEBI_104011|http://purl.obolibrary.org/obo/CHEBI_31204|http://purl.obolibrary.org/obo/CHEBI_33848|http://purl.obolibrary.org/obo/CHEBI_53305
T489 44671-44673 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T491 44678-44680 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T493 44684-44686 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T495 44690-44692 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T497 44696-44698 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T499 44702-44704 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T501 44709-44711 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T503 44853-44856 Chemical denotes PAH http://purl.obolibrary.org/obo/CHEBI_104011|http://purl.obolibrary.org/obo/CHEBI_31204|http://purl.obolibrary.org/obo/CHEBI_33848|http://purl.obolibrary.org/obo/CHEBI_53305
T507 44916-44920 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T509 45010-45014 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T511 45081-45085 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T513 45162-45166 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T515 45197-45202 Chemical denotes ZnCl2 http://purl.obolibrary.org/obo/CHEBI_49976
T516 45249-45253 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T518 45330-45334 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T520 45417-45421 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T522 45460-45467 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T523 45494-45497 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T524 45523-45527 Chemical denotes ions http://purl.obolibrary.org/obo/CHEBI_24870
T525 45555-45559 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T527 45601-45605 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T529 45662-45666 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T531 45729-45739 Chemical denotes zinc oxide http://purl.obolibrary.org/obo/CHEBI_36560
T532 45729-45733 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T534 45734-45739 Chemical denotes oxide http://purl.obolibrary.org/obo/CHEBI_25741|http://purl.obolibrary.org/obo/CHEBI_29356
T536 45770-45783 Chemical denotes zinc chloride http://purl.obolibrary.org/obo/CHEBI_49976
T537 45770-45774 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T539 45775-45783 Chemical denotes chloride http://purl.obolibrary.org/obo/CHEBI_17996
T540 45784-45788 Chemical denotes salt http://purl.obolibrary.org/obo/CHEBI_24866|http://purl.obolibrary.org/obo/CHEBI_26710
T542 45853-45868 Chemical denotes food components http://purl.obolibrary.org/obo/CHEBI_78295
T543 45960-45970 Chemical denotes folic acid http://purl.obolibrary.org/obo/CHEBI_27470
T544 45966-45970 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T545 46005-46009 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T547 46024-46028 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T549 46059-46063 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T551 46100-46103 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T552 46142-46153 Chemical denotes amino acids http://purl.obolibrary.org/obo/CHEBI_33709
T553 46142-46147 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T554 46148-46153 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T555 46155-46157 Chemical denotes AA http://purl.obolibrary.org/obo/CHEBI_15843|http://purl.obolibrary.org/obo/CHEBI_72816|http://purl.obolibrary.org/obo/CHEBI_33709
T558 46199-46207 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T559 46214-46217 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T560 46247-46259 Chemical denotes amine groups http://purl.obolibrary.org/obo/CHEBI_51142
T561 46247-46252 Chemical denotes amine http://purl.obolibrary.org/obo/CHEBI_32952
T562 46276-46282 Chemical denotes anions http://purl.obolibrary.org/obo/CHEBI_22563
T563 46381-46386 Chemical denotes ZnCl2 http://purl.obolibrary.org/obo/CHEBI_49976
T564 46387-46391 Chemical denotes salt http://purl.obolibrary.org/obo/CHEBI_24866|http://purl.obolibrary.org/obo/CHEBI_26710
T566 46395-46397 Chemical denotes Zn http://purl.obolibrary.org/obo/CHEBI_27363
T567 46398-46400 Chemical denotes AA http://purl.obolibrary.org/obo/CHEBI_15843|http://purl.obolibrary.org/obo/CHEBI_72816|http://purl.obolibrary.org/obo/CHEBI_33709
T570 46444-46448 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T572 46626-46630 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T574 46643-46645 Chemical denotes AA http://purl.obolibrary.org/obo/CHEBI_15843|http://purl.obolibrary.org/obo/CHEBI_72816|http://purl.obolibrary.org/obo/CHEBI_33709
T577 46658-46662 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T579 46663-46668 Chemical denotes salts http://purl.obolibrary.org/obo/CHEBI_24866
T580 46719-46723 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T582 46739-46743 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T584 46744-46746 Chemical denotes AA http://purl.obolibrary.org/obo/CHEBI_15843|http://purl.obolibrary.org/obo/CHEBI_72816|http://purl.obolibrary.org/obo/CHEBI_33709
T587 46760-46762 Chemical denotes AA http://purl.obolibrary.org/obo/CHEBI_15843|http://purl.obolibrary.org/obo/CHEBI_72816|http://purl.obolibrary.org/obo/CHEBI_33709
T590 46825-46827 Chemical denotes AA http://purl.obolibrary.org/obo/CHEBI_15843|http://purl.obolibrary.org/obo/CHEBI_72816|http://purl.obolibrary.org/obo/CHEBI_33709
T593 46892-46896 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T595 46897-46899 Chemical denotes AA http://purl.obolibrary.org/obo/CHEBI_15843|http://purl.obolibrary.org/obo/CHEBI_72816|http://purl.obolibrary.org/obo/CHEBI_33709
T598 46952-46959 Chemical denotes insulin http://purl.obolibrary.org/obo/CHEBI_145810
T599 47035-47039 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T601 47171-47175 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T603 47326-47338 Chemical denotes dietary zinc http://purl.obolibrary.org/obo/CHEBI_29105
T604 47334-47338 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T606 47398-47401 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T607 47463-47467 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T609 47490-47497 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T610 47549-47552 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T611 47581-47583 Chemical denotes AA http://purl.obolibrary.org/obo/CHEBI_15843|http://purl.obolibrary.org/obo/CHEBI_72816|http://purl.obolibrary.org/obo/CHEBI_33709
T614 47594-47597 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T615 47639-47643 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T617 47722-47726 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T619 47774-47777 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T620 47832-47836 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T622 47919-47922 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T42913 48064-48068 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T61190 48155-48158 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T14672 48358-48362 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T35422 48381-48385 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T6498 48475-48479 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T46147 48572-48576 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T80373 48709-48713 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T99687 48918-48922 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T73526 48967-48979 Chemical denotes amyloid beta http://purl.obolibrary.org/obo/CHEBI_64645
T25126 48975-48979 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T81124 48980-48987 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T69400 49074-49082 Chemical denotes zinc ion http://purl.obolibrary.org/obo/CHEBI_27365
T43909 49074-49078 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T90698 49079-49082 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T23 49239-49242 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T11305 49271-49277 Chemical denotes metals http://purl.obolibrary.org/obo/CHEBI_33521
T25 49361-49365 Chemical denotes ions http://purl.obolibrary.org/obo/CHEBI_24870
T8552 49534-49537 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T27 49589-49593 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T46411 49632-49636 Chemical denotes EDTA http://purl.obolibrary.org/obo/CHEBI_42191|http://purl.obolibrary.org/obo/CHEBI_64755
T9001 49643-49651 Chemical denotes chelator http://purl.obolibrary.org/obo/CHEBI_38161
T72606 49804-49811 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T34459 49827-49831 Chemical denotes ions http://purl.obolibrary.org/obo/CHEBI_24870
T8109 49840-49844 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T36 49861-49870 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T35424 49884-49894 Chemical denotes fatty acid http://purl.obolibrary.org/obo/CHEBI_35366
T51103 49890-49894 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T4450 49896-49899 Chemical denotes FFA http://purl.obolibrary.org/obo/CHEBI_42638|http://purl.obolibrary.org/obo/CHEBI_35366
T26241 49977-49984 Chemical denotes carrier http://purl.obolibrary.org/obo/CHEBI_78059
T16974 49994-49998 Chemical denotes ions http://purl.obolibrary.org/obo/CHEBI_24870
T80700 50015-50024 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T93666 50060-50069 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T47509 50196-50199 Chemical denotes FFA http://purl.obolibrary.org/obo/CHEBI_42638|http://purl.obolibrary.org/obo/CHEBI_35366
T36449 50204-50208 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T66182 50261-50267 Chemical denotes carbon http://purl.obolibrary.org/obo/CHEBI_27594|http://purl.obolibrary.org/obo/CHEBI_33415
T10714 50268-50273 Chemical denotes atoms http://purl.obolibrary.org/obo/CHEBI_33250
T87033 50312-50315 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T84664 50424-50428 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T4649 50564-50568 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T68380 50711-50714 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T39438 50721-50733 Chemical denotes amyloid beta http://purl.obolibrary.org/obo/CHEBI_64645
T95341 50729-50733 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T90891 50734-50742 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T79507 50800-50803 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T11769 50891-50898 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T88200 51190-51194 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T72355 51260-51263 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T765 51429-51433 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T83715 51494-51499 Chemical denotes ZnCl2 http://purl.obolibrary.org/obo/CHEBI_49976
T56869 51500-51503 Chemical denotes ZnO http://purl.obolibrary.org/obo/CHEBI_36560
T70147 51504-51520 Chemical denotes hexachloroethane http://purl.obolibrary.org/obo/CHEBI_39227
T4674 51776-51780 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T51227 51996-52000 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T75 53487-53497 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T47611 53617-53626 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T93730 53703-53711 Chemical denotes electron http://purl.obolibrary.org/obo/CHEBI_10545
T82543 53949-53956 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T74998 54023-54030 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T37661 54291-54299 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T59859 54388-54395 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T68655 54573-54581 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T22243 54663-54672 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T66791 54721-54730 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T85 54819-54827 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T26019 54874-54888 Chemical denotes ACE2 inhibitor http://purl.obolibrary.org/obo/CHEBI_147289
T54501 54879-54888 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T75789 54960-54975 Chemical denotes racemic mixture http://purl.obolibrary.org/obo/CHEBI_60911
T7082 54968-54975 Chemical denotes mixture http://purl.obolibrary.org/obo/CHEBI_60004
T14426 55162-55177 Chemical denotes racemic mixture http://purl.obolibrary.org/obo/CHEBI_60911
T52319 55170-55177 Chemical denotes mixture http://purl.obolibrary.org/obo/CHEBI_60004
T74419 55313-55323 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T93878 55430-55438 Chemical denotes racemate http://purl.obolibrary.org/obo/CHEBI_60911
T90533 55583-55591 Chemical denotes racemate http://purl.obolibrary.org/obo/CHEBI_60911
T46386 55702-55712 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T96 55916-55924 Chemical denotes racemate http://purl.obolibrary.org/obo/CHEBI_60911
T36982 56058-56072 Chemical denotes ACE2 inhibitor http://purl.obolibrary.org/obo/CHEBI_147289
T92521 56063-56072 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T41578 56270-56279 Chemical denotes disulfide http://purl.obolibrary.org/obo/CHEBI_48343
T100 56304-56314 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T22298 56671-56673 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T60880 56905-56913 Chemical denotes racemate http://purl.obolibrary.org/obo/CHEBI_60911
T91051 57027-57037 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T32362 57342-57356 Chemical denotes ACE2 inhibitor http://purl.obolibrary.org/obo/CHEBI_147289
T91312 57347-57356 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T3770 57379-57388 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T42358 57766-57768 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T84420 58020-58025 Chemical denotes water http://purl.obolibrary.org/obo/CHEBI_15377
T69860 58057-58061 Chemical denotes male http://purl.obolibrary.org/obo/CHEBI_30780
T80273 58392-58399 Chemical denotes nucleus http://purl.obolibrary.org/obo/CHEBI_33252
T43819 58747-58756 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T58470 58859-58866 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T85380 58867-58881 Chemical denotes ACE2 inhibitor http://purl.obolibrary.org/obo/CHEBI_147289
T2332 58872-58881 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T27493 59006-59015 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T56128 59240-59249 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T23596 59388-59403 Chemical denotes ACE2 inhibitors http://purl.obolibrary.org/obo/CHEBI_147289
T10113 59393-59403 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T6036 59717-59721 Chemical denotes male http://purl.obolibrary.org/obo/CHEBI_30780
T60127 59782-59785 Chemical denotes C16 http://purl.obolibrary.org/obo/CHEBI_15756
T121 59841-59849 Chemical denotes solution http://purl.obolibrary.org/obo/CHEBI_75958
T93537 59875-59880 Chemical denotes water http://purl.obolibrary.org/obo/CHEBI_15377
T27633 60032-60037 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T73784 60840-60846 Chemical denotes cation http://purl.obolibrary.org/obo/CHEBI_36916
T52408 60847-60852 Chemical denotes anion http://purl.obolibrary.org/obo/CHEBI_22563
T48403 60903-60907 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T22224 60956-60960 Chemical denotes EDTA http://purl.obolibrary.org/obo/CHEBI_42191|http://purl.obolibrary.org/obo/CHEBI_64755
T5627 60964-60970 Chemical denotes cation http://purl.obolibrary.org/obo/CHEBI_36916
T70245 60971-60979 Chemical denotes chelator http://purl.obolibrary.org/obo/CHEBI_38161
T22254 61051-61055 Chemical denotes EDTA http://purl.obolibrary.org/obo/CHEBI_42191|http://purl.obolibrary.org/obo/CHEBI_64755
T68253 61104-61107 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T95886 61252-61255 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T85661 61293-61297 Chemical denotes iron http://purl.obolibrary.org/obo/CHEBI_18248
T94180 61355-61359 Chemical denotes iron http://purl.obolibrary.org/obo/CHEBI_18248
T30043 61472-61476 Chemical denotes ions http://purl.obolibrary.org/obo/CHEBI_24870
T94269 61528-61532 Chemical denotes EDTA http://purl.obolibrary.org/obo/CHEBI_42191|http://purl.obolibrary.org/obo/CHEBI_64755
T6513 61546-61549 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T20754 61668-61672 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T40517 61742-61746 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T43428 61776-61780 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T36225 61875-61879 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T30838 61934-61938 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T53337 62424-62445 Chemical denotes iron chelating agents http://purl.obolibrary.org/obo/CHEBI_38157
T25372 62424-62428 Chemical denotes iron http://purl.obolibrary.org/obo/CHEBI_18248
T27100 62429-62445 Chemical denotes chelating agents http://purl.obolibrary.org/obo/CHEBI_38161
T154 62477-62485 Chemical denotes zinc ion http://purl.obolibrary.org/obo/CHEBI_27365
T155 62477-62481 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T83733 62482-62485 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T158 62583-62599 Chemical denotes chelating agents http://purl.obolibrary.org/obo/CHEBI_38161
T43731 62618-62622 Chemical denotes ions http://purl.obolibrary.org/obo/CHEBI_24870
T75520 62631-62635 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T86735 62743-62747 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T55396 62805-62809 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T79616 62981-62985 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T58337 63043-63059 Chemical denotes chelating agents http://purl.obolibrary.org/obo/CHEBI_38161
T33902 63098-63102 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T76669 63353-63357 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T173 63372-63381 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T19266 63426-63430 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T6825 63529-63540 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T177 63580-63584 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T70735 63727-63731 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T181 63746-63750 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T183 63789-63792 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T41696 63868-63879 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T185 64028-64031 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T99734 64208-64211 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T86289 64340-64351 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T188 64383-64389 Chemical denotes cation http://purl.obolibrary.org/obo/CHEBI_36916
T41096 64390-64406 Chemical denotes chelating agents http://purl.obolibrary.org/obo/CHEBI_38161
T99407 64574-64577 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T191 64679-64695 Chemical denotes chelating agents http://purl.obolibrary.org/obo/CHEBI_38161
T97596 65082-65086 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T61973 65098-65102 Chemical denotes EDTA http://purl.obolibrary.org/obo/CHEBI_42191|http://purl.obolibrary.org/obo/CHEBI_64755
T73647 65216-65220 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T92153 65300-65316 Chemical denotes chelating agents http://purl.obolibrary.org/obo/CHEBI_38161
T53011 65508-65511 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T9812 65587-65590 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T87402 65641-65650 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T44967 65734-65743 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T3727 65841-65848 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T14121 65902-65904 Chemical denotes AA http://purl.obolibrary.org/obo/CHEBI_15843|http://purl.obolibrary.org/obo/CHEBI_72816
T84458 65922-65929 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T69057 66004-66006 Chemical denotes AA http://purl.obolibrary.org/obo/CHEBI_15843|http://purl.obolibrary.org/obo/CHEBI_72816
T91071 66019-66023 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T19503 66039-66043 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T46424 66057-66068 Chemical denotes amino acids http://purl.obolibrary.org/obo/CHEBI_33709
T65597 66057-66062 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T8159 66063-66068 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T14330 66120-66122 Chemical denotes AA http://purl.obolibrary.org/obo/CHEBI_15843|http://purl.obolibrary.org/obo/CHEBI_72816
T85515 66140-66147 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T32788 66507-66517 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T79856 66507-66512 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T15688 66513-66517 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T92075 66521-66529 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T25025 66604-66608 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T1810 66640-66655 Chemical denotes ACE2 inhibitors http://purl.obolibrary.org/obo/CHEBI_147289
T34831 66645-66655 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T28604 66657-66665 Chemical denotes agmatine http://purl.obolibrary.org/obo/CHEBI_17431|http://purl.obolibrary.org/obo/CHEBI_58145
T22491 66682-66690 Chemical denotes arginine http://purl.obolibrary.org/obo/CHEBI_16467|http://purl.obolibrary.org/obo/CHEBI_29016|http://purl.obolibrary.org/obo/CHEBI_32696
T28753 66743-66757 Chemical denotes ACE2 inhibitor http://purl.obolibrary.org/obo/CHEBI_147289
T2369 66748-66757 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T78716 66787-66795 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T50950 66921-66928 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T79228 67020-67034 Chemical denotes ACE2 inhibitor http://purl.obolibrary.org/obo/CHEBI_147289
T7622 67025-67034 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T71996 67115-67123 Chemical denotes agmatine http://purl.obolibrary.org/obo/CHEBI_17431|http://purl.obolibrary.org/obo/CHEBI_58145
T88126 67583-67591 Chemical denotes agmatine http://purl.obolibrary.org/obo/CHEBI_17431|http://purl.obolibrary.org/obo/CHEBI_58145
T22869 67680-67688 Chemical denotes agmatine http://purl.obolibrary.org/obo/CHEBI_17431|http://purl.obolibrary.org/obo/CHEBI_58145
T85420 67775-67783 Chemical denotes agmatine http://purl.obolibrary.org/obo/CHEBI_17431|http://purl.obolibrary.org/obo/CHEBI_58145
T82274 67784-67791 Chemical denotes sulfate http://purl.obolibrary.org/obo/CHEBI_16189
T71277 67861-67877 Chemical denotes chelating agents http://purl.obolibrary.org/obo/CHEBI_38161
T50847 67892-67902 Chemical denotes folic acid http://purl.obolibrary.org/obo/CHEBI_27470
T11602 67898-67902 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T248 67911-67927 Chemical denotes chelating agents http://purl.obolibrary.org/obo/CHEBI_38161
T86761 67962-67966 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T13737 68063-68076 Chemical denotes nicotianamine http://purl.obolibrary.org/obo/CHEBI_25520|http://purl.obolibrary.org/obo/CHEBI_58249
T39108 68149-68157 Chemical denotes chelator http://purl.obolibrary.org/obo/CHEBI_38161
T254 68190-68203 Chemical denotes metal cations http://purl.obolibrary.org/obo/CHEBI_25213
T55642 68196-68203 Chemical denotes cations http://purl.obolibrary.org/obo/CHEBI_36916
T80399 68205-68218 Chemical denotes Nicotianamine http://purl.obolibrary.org/obo/CHEBI_17721
T257 68266-68270 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T41173 68372-68376 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T99158 68406-68411 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T63352 68431-68439 Chemical denotes minerals http://purl.obolibrary.org/obo/CHEBI_46662
T15395 68646-68651 Chemical denotes water http://purl.obolibrary.org/obo/CHEBI_15377
T62193 68659-68665 Chemical denotes metals http://purl.obolibrary.org/obo/CHEBI_33521
T31321 68667-68674 Chemical denotes cations http://purl.obolibrary.org/obo/CHEBI_36916
T24234 68684-68690 Chemical denotes toxins http://purl.obolibrary.org/obo/CHEBI_27026
T54933 68783-68791 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T45243 69067-69077 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T93394 69417-69420 Chemical denotes PAH http://purl.obolibrary.org/obo/CHEBI_104011|http://purl.obolibrary.org/obo/CHEBI_31204|http://purl.obolibrary.org/obo/CHEBI_33848|http://purl.obolibrary.org/obo/CHEBI_53305
T26208 69624-69631 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T274 69768-69771 Chemical denotes PAH http://purl.obolibrary.org/obo/CHEBI_104011|http://purl.obolibrary.org/obo/CHEBI_31204|http://purl.obolibrary.org/obo/CHEBI_33848|http://purl.obolibrary.org/obo/CHEBI_53305
T27957 70107-70111 Chemical denotes male http://purl.obolibrary.org/obo/CHEBI_30780
T23518 70411-70427 Chemical denotes antihypertensive http://purl.obolibrary.org/obo/CHEBI_35674
T31593 70447-70471 Chemical denotes calcium channel blockers http://purl.obolibrary.org/obo/CHEBI_38215
T57795 70447-70454 Chemical denotes calcium http://purl.obolibrary.org/obo/CHEBI_22984|http://purl.obolibrary.org/obo/CHEBI_29320
T11914 70779-70783 Chemical denotes male http://purl.obolibrary.org/obo/CHEBI_30780
T62420 71181-71195 Chemical denotes ACE inhibitors http://purl.obolibrary.org/obo/CHEBI_35457
T88754 71185-71195 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T52738 71197-71202 Chemical denotes ACEIs http://purl.obolibrary.org/obo/CHEBI_35457
T63223 71400-71412 Chemical denotes antidiabetic http://purl.obolibrary.org/obo/CHEBI_35526
T53003 71480-71485 Chemical denotes ACEIs http://purl.obolibrary.org/obo/CHEBI_35457
T85209 71602-71610 Chemical denotes losartan http://purl.obolibrary.org/obo/CHEBI_6541
T35617 71629-71639 Chemical denotes lisinopril http://purl.obolibrary.org/obo/CHEBI_43755
T72244 72311-72318 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T44056 72456-72458 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T66080 72534-72539 Chemical denotes ACEIs http://purl.obolibrary.org/obo/CHEBI_35457
T91113 72812-72828 Chemical denotes antihypertensive http://purl.obolibrary.org/obo/CHEBI_35674
T28525 73315-73337 Chemical denotes antihypertensive drugs http://purl.obolibrary.org/obo/CHEBI_35674
T296 73332-73337 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T83523 73494-73499 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T76894 73509-73514 Chemical denotes ACEIs http://purl.obolibrary.org/obo/CHEBI_35457
T83214 73549-73554 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T89355 73615-73620 Chemical denotes ACEIs http://purl.obolibrary.org/obo/CHEBI_35457
T57644 73822-73830 Chemical denotes losartan http://purl.obolibrary.org/obo/CHEBI_6541
T96201 73951-73956 Chemical denotes ACEIs http://purl.obolibrary.org/obo/CHEBI_35457
T89890 74135-74140 Chemical denotes ACEIs http://purl.obolibrary.org/obo/CHEBI_35457
T31128 74270-74275 Chemical denotes ACEIs http://purl.obolibrary.org/obo/CHEBI_35457
T305 74351-74353 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T70014 74632-74639 Chemical denotes insulin http://purl.obolibrary.org/obo/CHEBI_145810
T54852 74797-74804 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T20423 75201-75205 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T36620 75676-75680 Chemical denotes male http://purl.obolibrary.org/obo/CHEBI_30780
T5528 75955-75964 Chemical denotes biomarker http://purl.obolibrary.org/obo/CHEBI_59163
T81193 76154-76161 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T20258 76701-76704 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T31895 76877-76881 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T31980 77008-77015 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T64545 77077-77081 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T71170 77230-77233 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T91526 77327-77334 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T21622 77445-77447 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T17216 77478-77488 Chemical denotes olmesartan http://purl.obolibrary.org/obo/CHEBI_48416
T323 77720-77723 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T37828 77991-77998 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T325 79239-79242 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T326 79832-79836 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T10662 79976-79979 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T32041 80020-80023 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T94142 81419-81422 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T63956 81896-81898 Chemical denotes Co http://purl.obolibrary.org/obo/CHEBI_27638
T17899 82415-82421 Chemical denotes ligand http://purl.obolibrary.org/obo/CHEBI_52214
T85067 82689-82691 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T11466 82695-82697 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T76645 82704-82706 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T29103 82903-82905 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T71125 83000-83002 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T17181 83306-83308 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T32883 83537-83539 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T39306 83804-83807 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T347 83958-83966 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T5939 84060-84062 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T50578 84093-84096 Chemical denotes Arg http://purl.obolibrary.org/obo/CHEBI_16467|http://purl.obolibrary.org/obo/CHEBI_29952
T10557 84100-84110 Chemical denotes bradykinin http://purl.obolibrary.org/obo/CHEBI_3165
T93575 84128-84138 Chemical denotes metabolite http://purl.obolibrary.org/obo/CHEBI_25212
T353 84139-84149 Chemical denotes bradykinin http://purl.obolibrary.org/obo/CHEBI_3165
T30551 84946-84949 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T24736 85026-85040 Chemical denotes ACE2 inhibitor http://purl.obolibrary.org/obo/CHEBI_147289
T58502 85031-85040 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T53764 85081-85086 Chemical denotes ZnCl2 http://purl.obolibrary.org/obo/CHEBI_49976
T36058 85391-85397 Chemical denotes ligand http://purl.obolibrary.org/obo/CHEBI_52214
T52995 85565-85567 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T40147 85695-85706 Chemical denotes metabolites http://purl.obolibrary.org/obo/CHEBI_25212
T54329 85716-85726 Chemical denotes bradykinin http://purl.obolibrary.org/obo/CHEBI_3165
T56689 86006-86014 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T363 86142-86144 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T78190 86490-86492 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T365 86800-86810 Chemical denotes bradykinin http://purl.obolibrary.org/obo/CHEBI_3165
T60418 86967-86970 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T367 86971-86979 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T44489 87197-87200 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T51967 87386-87391 Chemical denotes ZnCl2 http://purl.obolibrary.org/obo/CHEBI_49976
T99879 87626-87629 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T49537 87729-87731 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T372 88046-88049 Chemical denotes PAH http://purl.obolibrary.org/obo/CHEBI_104011|http://purl.obolibrary.org/obo/CHEBI_31204|http://purl.obolibrary.org/obo/CHEBI_33848|http://purl.obolibrary.org/obo/CHEBI_53305
T91178 88828-88831 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T58980 88832-88840 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T378 89020-89027 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T26334 89054-89057 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T35856 89058-89065 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T381 89146-89149 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T7608 89150-89166 Chemical denotes enzyme inhibitor http://purl.obolibrary.org/obo/CHEBI_23924
T37031 89157-89166 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T58491 89367-89374 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T68902 89458-89461 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T70747 89462-89470 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T79938 89567-89570 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T12905 89571-89579 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T81984 89592-89594 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T70319 89776-89784 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T92568 89961-89968 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T60136 90051-90053 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T393 90180-90182 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T64017 90265-90267 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T395 90522-90525 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T48166 90526-90534 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T20626 90721-90723 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T398 90884-90886 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T65534 91085-91088 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T400 91089-91096 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T38942 91159-91161 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T402 91379-91381 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T73386 91443-91445 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T404 91537-91539 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T51662 91579-91582 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T406 91583-91591 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T43612 91732-91734 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T408 92746-92748 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T14109 92777-92779 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T410 93120-93123 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T34953 93203-93206 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T412 93343-93345 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T44343 93517-93520 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T414 93780-93788 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T30845 94197-94200 Chemical denotes PAH http://purl.obolibrary.org/obo/CHEBI_104011|http://purl.obolibrary.org/obo/CHEBI_31204|http://purl.obolibrary.org/obo/CHEBI_33848|http://purl.obolibrary.org/obo/CHEBI_53305
T49181 94281-94283 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T420 94298-94306 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T36261 94508-94510 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T422 94585-94588 Chemical denotes PAH http://purl.obolibrary.org/obo/CHEBI_104011|http://purl.obolibrary.org/obo/CHEBI_31204|http://purl.obolibrary.org/obo/CHEBI_33848|http://purl.obolibrary.org/obo/CHEBI_53305
T426 94727-94734 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T62058 94849-94852 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T428 94853-94860 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T22916 95567-95585 Chemical denotes pathway inhibitors http://purl.obolibrary.org/obo/CHEBI_76932
T430 95575-95585 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T28021 95598-95609 Chemical denotes antagonists http://purl.obolibrary.org/obo/CHEBI_48706
T432 95623-95633 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T48464 95647-95656 Chemical denotes chelators http://purl.obolibrary.org/obo/CHEBI_38161
T39924 95676-95685 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T21519 95874-95892 Chemical denotes pathway inhibitors http://purl.obolibrary.org/obo/CHEBI_76932
T436 95882-95892 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T33321 96179-96188 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T438 96199-96202 Chemical denotes C16 http://purl.obolibrary.org/obo/CHEBI_15756
T62485 96355-96358 Chemical denotes C16 http://purl.obolibrary.org/obo/CHEBI_15756
T440 96396-96406 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T25711 96592-96602 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T33721 96729-96747 Chemical denotes pathway inhibitors http://purl.obolibrary.org/obo/CHEBI_76932
T20781 96737-96747 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T88121 96885-96888 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T445 97201-97209 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T21827 97229-97243 Chemical denotes ACE2 inhibitor http://purl.obolibrary.org/obo/CHEBI_147289
T447 97234-97243 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T82941 97259-97262 Chemical denotes C16 http://purl.obolibrary.org/obo/CHEBI_15756
T449 97610-97618 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T63759 98446-98451 Chemical denotes water http://purl.obolibrary.org/obo/CHEBI_15377
T53319 98458-98466 Chemical denotes solution http://purl.obolibrary.org/obo/CHEBI_75958
T52282 98509-98517 Chemical denotes solution http://purl.obolibrary.org/obo/CHEBI_75958
T57829 98545-98552 Chemical denotes insulin http://purl.obolibrary.org/obo/CHEBI_145810
T12810 98678-98682 Chemical denotes salt http://purl.obolibrary.org/obo/CHEBI_24866|http://purl.obolibrary.org/obo/CHEBI_26710
T39693 98856-98864 Chemical denotes solution http://purl.obolibrary.org/obo/CHEBI_75958
T31089 98888-98900 Chemical denotes cyclodextrin http://purl.obolibrary.org/obo/CHEBI_23456
T9 98913-98916 Chemical denotes H2O http://purl.obolibrary.org/obo/CHEBI_15377
T3495 99105-99119 Chemical denotes pharmaceutical http://purl.obolibrary.org/obo/CHEBI_52217
T11 99365-99369 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T72202 99833-99837 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T58611 100207-100216 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T57445 100840-100843 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T42648 101298-101306 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T66997 101381-101385 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T55490 102080-102089 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T79112 102423-102426 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T25987 102505-102515 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T36125 102517-102526 Chemical denotes aliskiren http://purl.obolibrary.org/obo/CHEBI_601027
T21 102565-102570 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T68125 102760-102765 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T76956 102941-102944 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T7372 102957-102966 Chemical denotes aliskiren http://purl.obolibrary.org/obo/CHEBI_601027
T80351 103037-103041 Chemical denotes fuel http://purl.obolibrary.org/obo/CHEBI_33292
T53522 103262-103264 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T46892 103279-103286 Chemical denotes ligands http://purl.obolibrary.org/obo/CHEBI_52214
T73943 103536-103539 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T15324 103558-103564 Chemical denotes cation http://purl.obolibrary.org/obo/CHEBI_36916
T26128 103565-103581 Chemical denotes chelating agents http://purl.obolibrary.org/obo/CHEBI_38161
T93640 103603-103616 Chemical denotes nicotianamine http://purl.obolibrary.org/obo/CHEBI_25520|http://purl.obolibrary.org/obo/CHEBI_58249
T78307 103720-103736 Chemical denotes chelating agents http://purl.obolibrary.org/obo/CHEBI_38161
T50244 103750-103754 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T86055 103996-104012 Chemical denotes chelating agents http://purl.obolibrary.org/obo/CHEBI_38161
T24696 104132-104135 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T59302 104183-104193 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T40754 104200-104216 Chemical denotes chelating agents http://purl.obolibrary.org/obo/CHEBI_38161
T43600 104264-104269 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T37560 104378-104383 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T45827 104491-104494 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T9258 104566-104569 Chemical denotes PAH http://purl.obolibrary.org/obo/CHEBI_104011|http://purl.obolibrary.org/obo/CHEBI_31204|http://purl.obolibrary.org/obo/CHEBI_33848|http://purl.obolibrary.org/obo/CHEBI_53305
T27101 104660-104662 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T63845 104765-104768 Chemical denotes PAH http://purl.obolibrary.org/obo/CHEBI_104011|http://purl.obolibrary.org/obo/CHEBI_31204|http://purl.obolibrary.org/obo/CHEBI_33848|http://purl.obolibrary.org/obo/CHEBI_53305
T5467 104870-104873 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T76100 105642-105650 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T57881 105701-105708 Chemical denotes calcium http://purl.obolibrary.org/obo/CHEBI_22984|http://purl.obolibrary.org/obo/CHEBI_29320
T83360 105767-105775 Chemical denotes antidote http://purl.obolibrary.org/obo/CHEBI_50247
T37122 105818-105822 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T27252 105823-105831 Chemical denotes chelator http://purl.obolibrary.org/obo/CHEBI_38161
T65049 106099-106103 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T28613 106136-106140 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T82046 106183-106187 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T31373 106457-106461 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T61878 107314-107318 Chemical denotes EDTA http://purl.obolibrary.org/obo/CHEBI_42191|http://purl.obolibrary.org/obo/CHEBI_64755
T17876 107453-107469 Chemical denotes chelating agents http://purl.obolibrary.org/obo/CHEBI_38161
T48035 107759-107767 Chemical denotes chelator http://purl.obolibrary.org/obo/CHEBI_38161
T62900 109164-109167 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T20847 109179-109183 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T4937 109215-109217 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T2350 109261-109271 Chemical denotes bradykinin http://purl.obolibrary.org/obo/CHEBI_3165
T24872 110005-110008 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T53946 110009-110017 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T12617 110723-110726 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T93364 110727-110737 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T25023 110791-110795 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T91571 110818-110832 Chemical denotes ACE2 inhibitor http://purl.obolibrary.org/obo/CHEBI_147289
T70701 110823-110832 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T14447 110917-110921 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T92382 111135-111139 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T52971 111200-111203 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 99155-99168 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammations
T2 100243-100255 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T3 101803-101820 http://purl.obolibrary.org/obo/GO_0007596 denotes blood/coagulation
T4 101809-101820 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T5 103809-103818 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T6 106183-106194 http://purl.obolibrary.org/obo/GO_0071578 denotes zinc uptake
T7 106188-106194 http://purl.obolibrary.org/obo/GO_0098739 denotes uptake
T8 106188-106194 http://purl.obolibrary.org/obo/GO_0098657 denotes uptake
T9 106393-106402 http://purl.obolibrary.org/obo/GO_0007588 denotes excretion
T10 107732-107753 http://purl.obolibrary.org/obo/GO_0003094 denotes glomerular filtration
T11 110039-110051 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T46890 640-645 http://purl.obolibrary.org/obo/GO_0007568 denotes Aging
T87124 1638-1654 http://purl.obolibrary.org/obo/GO_0016032 denotes Viral infections
T52159 4757-4772 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T47565 5220-5235 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T51579 5998-6013 http://purl.obolibrary.org/obo/GO_0010467 denotes gene expression
T1132 6686-6698 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T66720 6828-6837 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T54884 8490-8512 http://purl.obolibrary.org/obo/GO_0006865 denotes amino acid transporter
T58005 10208-10221 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T37916 10774-10781 http://purl.obolibrary.org/obo/GO_0009606 denotes tropism
T72358 11566-11573 http://purl.obolibrary.org/obo/GO_0009606 denotes tropism
T98067 12557-12573 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T13 13295-13309 http://purl.obolibrary.org/obo/GO_0042311 denotes vasodilatative
T14 13795-13811 http://purl.obolibrary.org/obo/GO_0042310 denotes vasoconstriction
T15 13826-13838 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T16 13850-13868 http://purl.obolibrary.org/obo/GO_0008283 denotes cell proliferation
T17 14387-14399 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T18 15350-15359 http://purl.obolibrary.org/obo/GO_0005243 denotes connexins
T19 15385-15394 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T20 16033-16044 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T21 16190-16199 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T22 16344-16364 http://purl.obolibrary.org/obo/GO_0070527 denotes platelet aggregation
T23 16807-16818 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T24 16870-16881 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T25 17066-17075 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T26 17439-17458 http://purl.obolibrary.org/obo/GO_0001666 denotes response to hypoxia
T27 18307-18317 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T28 18797-18816 http://purl.obolibrary.org/obo/GO_0001666 denotes response to hypoxia
T29 19584-19596 http://purl.obolibrary.org/obo/GO_0042311 denotes vasodilation
T30 20095-20104 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T31 20557-20566 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T32 20762-20781 http://purl.obolibrary.org/obo/GO_0001816 denotes cytokine production
T33 20834-20846 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T34 21389-21404 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T35 22207-22216 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T36 22207-22216 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T37 22330-22342 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T38 22785-22794 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T39 22870-22893 http://purl.obolibrary.org/obo/GO_0007263 denotes nitric oxide signalling
T40 22883-22893 http://purl.obolibrary.org/obo/GO_0023052 denotes signalling
T41 22910-22926 http://purl.obolibrary.org/obo/GO_0032613 denotes IL-10 production
T42 23174-23190 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T43 23234-23246 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T44 23906-23921 http://purl.obolibrary.org/obo/GO_0010467 denotes gene expression
T45 24044-24057 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T46 25085-25095 http://purl.obolibrary.org/obo/GO_0023052 denotes signalling
T47 25409-25422 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T48 25561-25571 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T49 25865-25882 http://purl.obolibrary.org/obo/GO_0038024 denotes receptor activity
T50 27376-27385 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T51 28390-28399 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T52 28467-28476 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T53 29030-29039 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T54 29175-29190 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T55 29462-29471 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T56 29698-29712 http://purl.obolibrary.org/obo/GO_0042311 denotes vasodilatative
T57 29743-29753 http://purl.obolibrary.org/obo/GO_0009056 denotes catabolism
T58 30054-30076 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory responses
T59 30423-30432 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T60 31225-31236 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T61 31270-31279 http://purl.obolibrary.org/obo/GO_0007588 denotes excretion
T62 31902-31914 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T63 33127-33151 http://purl.obolibrary.org/obo/GO_0008237 denotes metalloprotease activity
T64 33877-33893 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T65 33968-33993 http://purl.obolibrary.org/obo/GO_0002250 denotes adaptive immune responses
T66 34006-34020 http://purl.obolibrary.org/obo/GO_0005319 denotes apolipoprotein
T67 34023-34035 http://purl.obolibrary.org/obo/GO_0016556 denotes mRNA editing
T68 35756-35767 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T69 36009-36018 http://purl.obolibrary.org/obo/GO_0007588 denotes excretion
T70 38329-38341 http://purl.obolibrary.org/obo/GO_0042311 denotes vasodilation
T71 39434-39445 http://purl.obolibrary.org/obo/GO_0006810 denotes transporter
T72 41316-41327 http://purl.obolibrary.org/obo/GO_0071578 denotes zinc import
T73 42325-42334 http://purl.obolibrary.org/obo/GO_0007588 denotes excretion
T74 42493-42502 http://purl.obolibrary.org/obo/GO_0007588 denotes excretion
T75 44110-44128 http://purl.obolibrary.org/obo/GO_0001816 denotes cytokine secretion
T76 44119-44128 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T77 44308-44323 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T78 45081-45097 http://purl.obolibrary.org/obo/GO_0055069 denotes zinc homeostasis
T79 45081-45097 http://purl.obolibrary.org/obo/GO_0006882 denotes zinc homeostasis
T80 45086-45097 http://purl.obolibrary.org/obo/GO_0042592 denotes homeostasis
T81 45249-45265 http://purl.obolibrary.org/obo/GO_0055069 denotes zinc homeostasis
T82 45249-45265 http://purl.obolibrary.org/obo/GO_0006882 denotes zinc homeostasis
T83 45254-45265 http://purl.obolibrary.org/obo/GO_0042592 denotes homeostasis
T84 45417-45434 http://purl.obolibrary.org/obo/GO_0006829 denotes zinc transporters
T85 46064-46073 http://purl.obolibrary.org/obo/GO_0007588 denotes excretion
T86 46530-46551 http://purl.obolibrary.org/obo/GO_0050892 denotes intestinal absorption
T87 46709-46715 http://purl.obolibrary.org/obo/GO_0098739 denotes uptake
T88 46709-46715 http://purl.obolibrary.org/obo/GO_0098657 denotes uptake
T89 46729-46735 http://purl.obolibrary.org/obo/GO_0098739 denotes uptake
T90 46729-46735 http://purl.obolibrary.org/obo/GO_0098657 denotes uptake
T91 46828-46839 http://purl.obolibrary.org/obo/GO_0006810 denotes transporter
T92 46900-46906 http://purl.obolibrary.org/obo/GO_0098739 denotes uptake
T93 46900-46906 http://purl.obolibrary.org/obo/GO_0098657 denotes uptake
T94 46960-46972 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis
T95 46973-46982 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T96 47126-47135 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T97 47236-47257 http://purl.obolibrary.org/obo/GO_0050892 denotes intestinal absorption
T98 47268-47277 http://purl.obolibrary.org/obo/GO_0007588 denotes excretion
T99 47463-47479 http://purl.obolibrary.org/obo/GO_0006829 denotes zinc transporter
T100 47832-47843 http://purl.obolibrary.org/obo/GO_0071578 denotes zinc uptake
T101 47837-47843 http://purl.obolibrary.org/obo/GO_0098739 denotes uptake
T102 47837-47843 http://purl.obolibrary.org/obo/GO_0098657 denotes uptake
T103 48089-48098 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T104 48089-48098 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T105 48674-48684 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T106 48686-48703 http://purl.obolibrary.org/obo/GO_0007596 denotes blood coagulation
T107 48692-48703 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T108 48714-48724 http://purl.obolibrary.org/obo/GO_0023052 denotes signalling
T109 48834-48846 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T110 48995-49004 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T111 49589-49600 http://purl.obolibrary.org/obo/GO_0071578 denotes zinc uptake
T112 49594-49600 http://purl.obolibrary.org/obo/GO_0098739 denotes uptake
T113 49594-49600 http://purl.obolibrary.org/obo/GO_0098657 denotes uptake
T114 49690-49700 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T115 49794-49803 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T116 50609-50615 http://purl.obolibrary.org/obo/GO_0140352 denotes efflux
T117 50609-50615 http://purl.obolibrary.org/obo/GO_0140115 denotes efflux
T118 50761-50770 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T119 54939-54948 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T120 56401-56412 http://purl.obolibrary.org/obo/GO_0006508 denotes proteolysis
T121 56674-56685 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T122 58460-58466 http://purl.obolibrary.org/obo/GO_0060004 denotes reflex
T123 58520-58526 http://purl.obolibrary.org/obo/GO_0060004 denotes reflex
T124 59206-59218 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T125 61982-61988 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T126 61990-62010 http://purl.obolibrary.org/obo/GO_0048666 denotes neuronal development
T127 62872-62890 http://purl.obolibrary.org/obo/GO_0044249 denotes cellular synthesis
T128 62881-62890 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T129 62918-62927 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T130 63149-63158 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T131 63580-63591 http://purl.obolibrary.org/obo/GO_0071578 denotes zinc uptake
T132 63585-63591 http://purl.obolibrary.org/obo/GO_0098739 denotes uptake
T133 63585-63591 http://purl.obolibrary.org/obo/GO_0098657 denotes uptake
T134 63945-63964 http://purl.obolibrary.org/obo/GO_0030168 denotes platelet activation
T135 63993-64012 http://purl.obolibrary.org/obo/GO_0030168 denotes platelet activation
T136 64158-64167 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T137 65087-65096 http://purl.obolibrary.org/obo/GO_0007588 denotes excretion
T138 67329-67352 http://purl.obolibrary.org/obo/GO_0009889 denotes regulating NO synthesis
T139 67343-67352 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T140 67967-67988 http://purl.obolibrary.org/obo/GO_0050892 denotes intestinal absorption
T141 69278-69293 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T142 76095-76110 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T143 76712-76721 http://purl.obolibrary.org/obo/GO_0007588 denotes excretion
T144 77082-77091 http://purl.obolibrary.org/obo/GO_0007588 denotes excretion
T145 77241-77250 http://purl.obolibrary.org/obo/GO_0007588 denotes excretion
T146 78592-78597 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T147 78950-78955 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T148 79051-79063 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T149 79646-79651 http://purl.obolibrary.org/obo/GO_0030431 denotes sleep
T150 80604-80610 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T151 80614-80629 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T152 83665-83696 http://purl.obolibrary.org/obo/GO_0046718 denotes viral entry into the host cells
T153 83671-83690 http://purl.obolibrary.org/obo/GO_0044409 denotes entry into the host
T154 85673-85694 http://purl.obolibrary.org/obo/GO_0014863 denotes detection of inactive
T155 95801-95820 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T156 95808-95820 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T7 0-2 Sentence denotes 1.
T8 3-15 Sentence denotes Introduction
T9 16-193 Sentence denotes The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is the cause of the COVID-19 pandemic, for which there is currently no specific pharmacotherapy.
T10 194-436 Sentence denotes In the intensive care unit, depending on the severity of the COVID-19 infection, patients might receive supportive care such as oxygen supply, interferons, glucocorticoids, anti-virals, chloroquine, and macrolides given as deemed appropriate.
T11 437-639 Sentence denotes The SARS-CoV-2 infection produces either non-severe or severe symptoms and, in the latter case, it may precipitate into severe acute respiratory syndrome (SARS) and ultimately death [1,2,3,4,5,6,7,8,9].
T12 640-720 Sentence denotes Aging and different comorbidities are associated with patients’ critical status.
T13 721-907 Sentence denotes Most patients display lymphopaenia and eosinopaenia, and critical ones show extremely low levels of eosinophils, suggesting that eosinopaenia may be a potential diagnostic biomarker [1].
T14 908-1163 Sentence denotes Most serious cases of SARS are closely associated with cardiac dysfunction/injury, respiratory distress/illness, coagulopathy, hypoproteinaemia, acidosis, hypoxia and a cytokine storm mainly involving IL-1β, IL-6, IL-8, IL-10 and TNFα [1,2,3,4,5,6,7,8,9].
T15 1164-1637 Sentence denotes For instance, hypertension, an age-related disease, is the most common comorbidity (15–31% up to 24–58% in severe disease cases according to clinical reports), while only five cases of asthma (0.9%) were identified in one report of 548 infected patients in Wuhan [6], but no other asthmatic or allergic patients were described in other reports [1,2,3,4,5,7,8,9], considering that the overall prevalence of asthma is estimated to be 6.4% in Wuhan [6] and ~ 4% in China [10].
T16 1638-1803 Sentence denotes Viral infections usually increase the risk of allergic disease exacerbation [1]; however, the reported data seem to suggest that, in this case, the opposite is true.
T17 1804-2270 Sentence denotes Indeed, in more than 72.000 patient cohorts examined, the number of patients defined as asthmatic was low (5), which suggests that asthmatics might be protected from virus-induced SARS, whereas pre-existing hypertensive disease and/or pre-existing antihypertensive treatments may represent a risk factor for increased virus infection, considering that the overall prevalence of hypertension in Chinese adult population ≥18 years of age is estimated to be ~ 23% [11].
T18 2271-2573 Sentence denotes Therefore, according to the clinical picture of infected patients, Th2-mediated allergic diseases (usually with high eosinophil counts) may play a protective role against SARS (usually with low eosinophil counts), while yet unknown mechanisms related to hypertensive conditions may exacerbate symptoms.
T19 2574-2890 Sentence denotes To complete the picture, COVID-19 hospitalized patients suffering from chronic renal disease were usually low (0-3%) [1,2,3,4,5,6,7,8,9] if compared with the prevalence of the disease in China (10.2-11.3%) [12], suggesting that chronic kidney disease patients might be protected from COVID-19 as for asthma patients.
T20 2892-2894 Sentence denotes 2.
T21 2895-2943 Sentence denotes ACE2-mediated SARS-CoV and SARS-CoV-2 Infections
T22 2944-3107 Sentence denotes Angiotensin-converting enzyme 2 (ACE2) was identified as a receptor for the spike (S) protein of SARS-CoV, finally facilitating viral entry into target cells [13].
T23 3108-3301 Sentence denotes ACE2 is abundantly expressed in airway epithelial cells and vascular endothelial cells, and it is believed to play a crucial role in the mechanism of acute lung injury induced by SARS-CoV [14].
T24 3302-3555 Sentence denotes The ability of spike-Fc protein treatment (3h) to downregulate ACE2 protein expression has been shown in an in vitro system (cell lines) and also in vivo in lung cells of mice [14,15], suggesting that ACE2 pathway may be down-modulated during infection.
T25 3556-3698 Sentence denotes However, ACE2 is constitutively expressed and released from the apical cell surface of human airway epithelia into airway surface liquid [16].
T26 3699-3940 Sentence denotes Of note, its surface down-modulation upon spike protein challenge has been shown to be due to ACE2 shedding mediated by activation of extracellular ADAM17/TACE metalloprotease, which concomitantly induces shedding/production of TNFα [17,18].
T27 3941-4172 Sentence denotes Interestingly, ACE2 shedding is enhanced not only by binding with spike protein [17,18], but also by IL-1β and TNFα inflammatory cytokines [16], cytokines that are secreted at relatively high concentration in COVID-19 patients [2].
T28 4173-4457 Sentence denotes Moreover, soluble (s)ACE2 (induced or not by virus binding) released from human airway epithelia has been demonstrated to retain both its enzymatic activity and its binding ability for spike viral protein, finally reducing spike protein-mediated viral entry into target cells [16,17].
T29 4458-4622 Sentence denotes Therefore, the interaction of ACE2 with spike protein of SARS-CoV induces a cellular “protective” ACE2 shedding feedback response that initially limits viral entry.
T30 4623-4810 Sentence denotes Nevertheless, ADAM17/TACE-mediated ACE2 shedding or ACE2 enzymatic activity have been shown to intriguingly correlate positively with viral infection and disease complications [17,19,20].
T31 4811-5002 Sentence denotes In contrast, HNL63-CoV, which similarly binds to ACE2 through its spike protein, infects ACE2-bearing cells and mainly induces the common cold, leading to neither ACE2 shedding nor SARS [17].
T32 5003-5265 Sentence denotes Moreover, catalytically inactive forms of sACE2 can potently inhibit SARS-CoV infection [19,21], suggesting that events downstream of ACE2 shedding and/or its enzymatic activity may indirectly and subsequently favour viral infection and/or disease complications.
T33 5266-5537 Sentence denotes To this regard, sACE2 was also associated with myocardial pathological conditions [22] and cardiovascular complications including hypotension (known to enhance both renin and angiotensin I, the substrate of ACE/ACE2) and tachycardia were common in SARS-CoV patients [23].
T34 5538-5806 Sentence denotes Since spike protein has been shown to not inhibit ACE2 enzymatic activity that is retained by sACE2-spike protein complex [16,17,24] and, in general, sACE2 maintains its enzymatic activity, we cannot consider its higher circulating expression a mere disease biomarker.
T35 5807-5922 Sentence denotes Indeed, ACE2 shedding might repress its local function but it certainly enhances its circulating/systemic activity.
T36 5923-6251 Sentence denotes Interestingly, a recent integrative bioinformatics analysis shows that the gene expression of ACE2 in human bronchial cells infected with SARS-CoV is dramatically increased 24h after infection and remained at a high level for at least 2 days, suggesting that ACE2 may be involved in a positive feedback loop post-infection [25].
T37 6252-6554 Sentence denotes In the same report, it has been shown that ACE2 expression level in bronchial epithelium obtained by brushing from asthmatic and normal subjects was similar, suggesting that respiratory epithelial cells of healthy subjects and asthmatic patients have similar ability to bind to SARS-CoV-2 through ACE2.
T38 6555-6652 Sentence denotes Of note, ACE2 was also identified as the receptor for the novel spike protein of SARS-CoV-2 [13].
T39 6653-6816 Sentence denotes Although the role of ACE2 in the pathogenesis of SARS-CoV-2 and in inducing lung injury is still unknown, ACE2 behaves similarly to original SARS-CoV [13] (Box 1).
T40 6817-7003 Sentence denotes Box 1 The formation of spike-ACE2 protein complexes may initiate ACE2 systemic upregulation and may impair autologous antibody generation/recognition of anti-S1-Receptor Binding Domain.
T41 7004-7273 Sentence denotes The ACE2 interacts with the spike (S) protein, thereby serves as an entry receptor for SARS-CoVs, and this event is likely followed by conformational changes, cleavages and fusion of both spike viral and ACE2 proteins at the level of infected host cell plasma-membrane.
T42 7274-7459 Sentence denotes The SARS coronavirus surface spike glycoproteins consist of trimers formed by two spike, capsid-distal S1 and –proximal S2, protein regions, located on the outer envelope of the virion.
T43 7460-7716 Sentence denotes Spike proteins are clove-shaped trimers with three S1 heads and a trimeric S2 stalk that can bind the cellular ACE2 receptor when one S1 (possessing the receptor-binding domain) in the trimer adopts an “up” conformation (see Figure later in the Section 4).
T44 7717-8128 Sentence denotes The subsequent binding of ACE2 receptor to the spike glycoprotein triggers both the ADAM17-mediated ACE2 shedding and dissociation of S1 fragments by exogenous (furin-related or other) proteases from the spike trimer, which leads on one hand to one S1-ACE2 complex and two S1 free fragments, and on the other hand to fusion of S2 viral trimers and cellular membrane structures, finally producing cell infection.
T45 8129-8352 Sentence denotes The molecular mechanism model for SARS-CoV recognition and infection was well described by Song and collaborators [26] and a similar molecular interactions between SARS-CoV-2 and ACE2 has been recently hypothesized [27,28].
T46 8353-8545 Sentence denotes To complete the picture, a recent structural work reveals that the full-length human ACE2 is assembled as a dimer associated or not with amino acid transporter B0AT1, which sandwich ACE2 [28].
T47 8546-8683 Sentence denotes Binding of the spike protein trimer onto the ACE2 dimer suggests simultaneous binding of two spike protein trimers to an ACE2 dimer [28].
T48 8684-8952 Sentence denotes Each monomer of the ACE2 homodimer is composed of a membrane-proximal collectrin-like domain mediating homodimerization and necessary to position the molecule to the cell membrane, and of a membrane-distal ACE2 peptidase domain responsible for ACE2 substrate cleavage.
T49 8953-9139 Sentence denotes Collectrin-like domain consists of an extracellular ferredoxin-like fold domain, also called neck domain (residues 616 to 726), a single transmembrane helix and an intracellular segment.
T50 9140-9324 Sentence denotes The ACE2 cleavage site mediated by ADAM17/TACE has been predicted between amino acids 716 and 741 [16], which corresponds to neck-transmembrane boundary of ACE2 collectrin-like domain.
T51 9325-9557 Sentence denotes It is tempting to speculate that, after ACE2 shedding, S2 viral trimers may fuse with the residual ACE2 collectrin-like fragments (complexed or not with B0AT1 transporters) which are eventually exposed on the cell surface membranes.
T52 9558-9662 Sentence denotes A model for SARS-CoV’s internalization by target cells that was already proposed several years ago [29].
T53 9663-9908 Sentence denotes Then, when the virus is inside the cell, a second proteolytic cleavage mediated by endosomal proteases (such as TMPRSS2) in the S2 region of the spike-ACE2 fusion protein might be necessary for intracellular virus “release” and active infection.
T54 9909-10066 Sentence denotes Several S1-sACE2 complexes, free S1 fragments or sACE2 are likely released in bloodstream of COVID-19 infected patients by spike and ACE2 receptor cleavages.
T55 10067-10542 Sentence denotes As already mentioned, circulating sACE2 protein shedding independent on virus contact has been also described either spontaneously when ACE2 transcription is upregulated or upon cytokine activation; it is therefore likely that in the bloodstreams ACE2 proteins are available to bind to both free S1 fragments and SARS-CoV-2 particles, finally leading to more and more S1-sACE2 and SARS-CoV-2-sACE2 complexes bearing enzymatic active sACE2 (see Figure later in the Section 4).
T56 10543-10818 Sentence denotes Of note, SARS-CoV-2-sACE2 complexes, sequestrating sACE2, can drive part of the sACE2 systemic activity and concentrate it locally where the organs possess cells expressing ACE2 on their surface membrane, i.e., following the viral tropism (see Figure later in the Section 4).
T57 10819-11113 Sentence denotes Indeed, although the viral load in sputum of adult SARS-CoV patients was usually higher than 104 copies/mL, reports indicate that plasma viral RNA concentrations are low, usually lower than 190 copies/mL and lymphocytes have much higher RNA-copy concentrations of SARS-CoV RNA than plasma [30].
T58 11114-11259 Sentence denotes Very low RNA concentrations with no difference between patients with mild or severe symptoms were detected in plasma from COVID-19 patients [30].
T59 11260-11391 Sentence denotes The viral load in nasal swabs of asymptomatic and symptomatic COVID-19-positive subjects was also not significantly different [31].
T60 11392-11676 Sentence denotes Of interest, SARS-CoV infected pediatric patients have more than double the amount of plasma RNA copies/mL when compared to adult patients [30], suggesting a different viral tropism between adults and children (different cellular ACE2 expression possibly leading to Kawasaki disease).
T61 11677-11804 Sentence denotes Notably, free S1 fragments may have a decoy function for autologous/exogenous anti-S1-receptor binding domain (RBD) antibodies.
T62 11805-12035 Sentence denotes On the other hand, sACE2-S1 complexes masking S1-RBD might also impair either generation of autologous high affinity antibodies against S1-RBD or recognition/inactivation of S1-RBD on SARS-CoV-2 by autologous/exogenous antibodies.
T63 12036-12408 Sentence denotes Therefore, antibodies that do not compete with ACE2 for the binding to S1-RBD might be more effective in neutralizing SARS-CoV-2 [32,33], knowing that the number of spike proteins per virion is estimated to be around 70 and that every spike protein bears three S1 receptor binding domains, which are masked to autologous antibody recognition when in a “down” conformation.
T64 12409-12604 Sentence denotes These highly organized molecular features clearly demonstrate that the coronaviruses are armed with sophisticated infection machinery able to evade immune responses induced or not by vaccination.
T65 12605-12787 Sentence denotes Nevertheless, passive immunotherapy by means of convalescent plasma from COVID-19 recovered donors is a promising option for prevention and treatment of COVID-19 [32,33,34,35,36,37].
T66 12789-12791 Sentence denotes 3.
T67 12792-12841 Sentence denotes Pathological Effects of ACE2 Pathway Upregulation
T68 12842-12964 Sentence denotes ACE and ACE2 are two zinc metalloproteases involved in the biogenesis of the components of renin-angiotensin system (RAS).
T69 12965-13165 Sentence denotes ACE2 processes angiotensin (Ang) I and II into Ang (1–9) and Ang (1–7), respectively, and it also has other known peptide targets, such as des-Arg(9)-bradykinin, which mediates B1 receptor activation.
T70 13166-13512 Sentence denotes Ang (1–7) and Ang (1–9) peptides, opposing the effects of ACE/Ang II/Ang II type 1 receptor (AT1R) pathway, are known to mediate vasodilatative (hypotension), antiproliferative and apoptotic effects through Mas and AT2 receptors, respectively, both involving downstream nitric oxide synthase (NOS) pathway activation [38,39,40,41,42,43,44,45,46].
T71 13513-13668 Sentence denotes Physiology teaches us that there is a range of normality for every biological parameter, below (defect) and above (excess) of which there is a dysfunction.
T72 13669-13723 Sentence denotes This is likely to be true for ACE as well as for ACE2.
T73 13724-13938 Sentence denotes It is well known that excessive Ang II/AT1R pathway activation induces vasoconstriction, aldosterone, inflammation, excessive cell proliferation, thrombosis, cardiac dysfunction and lung alterations (see Figure 1).
T74 13939-14231 Sentence denotes Moreover, most of the experiments show that increased ACE2 activity leads to beneficial effects; however, the experiments were usually performed using models in which its “antagonist“ (ACE) pathway was upregulated or ACE2 itself was downregulated, therefore balancing an unbalanced situation.
T75 14232-14291 Sentence denotes What does it happen in models in which the opposite occurs?
T76 14292-14503 Sentence denotes (s)ACE2 or Ang (1–7) upregulation have been associated to some pathological conditions such as inflammation of the renal and gastrointestinal tract, cardiac dysfunction, human cirrhosis and lung injury/fibrosis.
T77 14504-14667 Sentence denotes Tissue/organ specific effects of excessive pathway activation that in some case resemble those produced by excessive Ang II/AT1R pathway activation (see Figure 1).
T78 14668-14807 Sentence denotes For example, systemic infusion of Ang (1–7) into mice had renal proinflammatory properties mediated by Mas receptor (MasR) activation [47].
T79 14808-14958 Sentence denotes Moreover, Ang (1–7) infusion was associated with increases in blood pressure, cardiac hypertrophy and fibrosis in rats with subtotal nephrectomy [48].
T80 14959-15139 Sentence denotes Similarly, elevated plasma sACE2 activity was associated both with greater severity of myocardial dysfunction and with an independent prediction of adverse clinical events [22,49].
T81 15140-15400 Sentence denotes Transgenic mice with increased cardiac ACE2 expression suffered from lethal ventricular arrhythmia (heart block, ventricular tachycardia and terminal ventricular fibrillation) consequent upon downregulation of connexins involved in gap junction formation [50].
T82 15401-15549 Sentence denotes In another model, ACE2 transgenic mice suffered from cardiac fibrosis with concomitant deficits in ejection fraction and fractional shortening [51].
T83 15550-15943 Sentence denotes Interestingly, in a rat model of myocardial infarction following coronary artery ligation, there is evidence that C16/MLN-4760 (a specific ACE2 inhibitor, see later) administration inhibits fibrosis and hypertrophy of non-infarcted myocardium and increases diastolic relaxation, raising the possibility that ACE2 activity may have some adverse effects on post-myocardial infarction heart [52].
T84 15944-16082 Sentence denotes The risk factors for cardiovascular disease include alterations in platelet function and coagulation with an increased risk of thrombosis.
T85 16083-16259 Sentence denotes Ang II and hypercholesterolemia are known to participate in microvascular thrombosis and enhanced thrombus formation in the microvasculature may contribute to microinfarctions.
T86 16260-16456 Sentence denotes To this end, in a rat model in which AT1R activation produce baseline thrombosis by platelet aggregation, Ang (1–9), known to bind AT2R [42], has been shown to enhance the thrombotic process [53].
T87 16457-16766 Sentence denotes Moreover, in a mouse model, AT2R activation (inhibited by AT2R antagonist, PD12319) mediated the onset of arteriolar microvascular thrombosis following chronic Ang II infusion [54], indicating both the recruitment of the AT2R pathway downstream of AT1R activation and its involvement in arteriolar thrombosis.
T88 16767-17076 Sentence denotes Of interest, disseminated intravascular coagulation is associated with hypoproteinaemia and deficit of coagulation and anticoagulation proteins, which can originate by their renal loss (and consequent proteinuria) and/or by their increased (pathological) consumption and/or by their reduced hepatic synthesis.
T89 17077-17285 Sentence denotes To this end, in healthy livers, ACE2 is limited to perivenular hepatocytes and endothelial cells; instead, in human hepatitis C cirrhosis, ACE2 protein expression is widespread in the hepatic parenchyma [55].
T90 17286-17477 Sentence denotes Notably, human hepatocytes cultured in hypoxic conditions upregulated ACE2 protein expression [55] and ACE2 mRNA, protein and activity were increased in response to hypoxia and by IL-1β [56].
T91 17478-17681 Sentence denotes In line with these observations, in peripheral blood human CD34+ cells, MasR expression and ACE2 expression, activity and shedding (of sACE2 catalytically active forms) were increased under hypoxia [57].
T92 17682-17939 Sentence denotes Moreover, under hypoxic conditions human pulmonary artery smooth muscle cells upregulated both (arms of the RAS) ACE and ACE2 mRNA and protein expression, and ACE2 was subsequently downregulated by (ACE-derived) Ang II through an AT1R-mediated process [58].
T93 17940-18125 Sentence denotes Similarly, both ACE and ACE2 expression were increased in vascular endothelium and smooth muscle of human left ventricle from patients with ischaemic (local hypoxia) heart disease [59].
T94 18126-18248 Sentence denotes Concomitant upregulation of both arms of the RAS that suggests a tight link between ACE and ACE2 under hypoxic conditions.
T95 18249-18387 Sentence denotes Indeed, several reports have shown a complex interplay of regulation between the two arms of the RAS independently on hypoxia (see Box 2).
T96 18388-18925 Sentence denotes Interestingly, chronic hypoxia induced activation of ACE2/Ang (1–7)/MasR axis and suppression of ACE/Ang II/AT1 receptor axis in lungs of pulmonary hypertensive Ren-2 transgenic rats (constructed by inserting the mouse Ren-2 renin gene) but not in normotensive transgene-negative control rats [60], suggesting that the baseline renin activity in hypertensive rats may be crucial to determine the differential response to hypoxia and that renin inhibition might be useful to inhibit the ACE to ACE2 pathway shift under hypoxic conditions.
T97 18926-19101 Sentence denotes Of interest, hypoxia alone or combined with hypercapnia has been shown to significantly increase both plasma renin expression or activity and plasma Ang II expression [61,62].
T98 19102-19597 Sentence denotes Moreover, hypercapnic acidosis (pH 6.8/6.9, a condition that could occur in SARS) induced in isolated rat lungs has been shown to induce a (compensatory) venular dilatation mediated by cyclooxygenase activation (inhibited by indomethacin) [63], an enzyme that has been shown to be induced downstream of Ang (1–7)/MasR pathway in isolated rat hearts (again inhibited by indomethacin) [64], suggesting the involvement of ACE2/Ang (1–7) pathway in mediating CO2-dependent lung venular vasodilation.
T99 19598-19993 Sentence denotes Altogether these observations indicate that there is a high probability that hypoxia/hypercapnia, a condition that occurs in SARS patients, might upregulate the activity of both arms of the RAS by suppling high amounts of renin product, Ang I, to ACE and ACE2, which, together, can produce high amounts of Ang II, Ang (1–9), Ang (1–7) and its (ACE-produced) metabolite, Ang (1–5) (see Figure 1).
T100 19994-20279 Sentence denotes Similarly to both Ang (1–7)/MasR and Ang (1–9)/AT2R pathways, Ang (1–5) has been shown to induce the secretion of atrial natriuretic peptide via MasR/NOS pathway in isolated perfused rat atria [65], indicating that Ang (1–5) is a heart active peptide (at least in Sprague-Dawley rats).
T101 20280-20446 Sentence denotes Interestingly, in the plasma of patients with inflammatory bowel disease, Ang (1–7) concentrations and (s)ACE2 activity were higher compared to healthy subjects [66].
T102 20447-20600 Sentence denotes Moreover, Ang (1–7) alone can either activate the Bax/Caspase–dependent apoptotic pathway or upregulate NF-kB signaling in lung fibroblast cultures [67].
T103 20601-20874 Sentence denotes Moreover, in vivo administration of Ang (1–7) alone (in Wistar rats) promoted morphological lung alterations, extracellular matrix accumulation and inflammatory cytokine production (including TNF-α and IL-6), characteristics of lung inflammation in pulmonary fibrosis [67].
T104 20875-20972 Sentence denotes Thereby, a condition that deteriorates respiratory compliance, could lead to hypoxia/hypercapnia.
T105 20973-21184 Sentence denotes Hypoxia, in turn, will induce ACE2 upregulation which possibly increases cardiac/lung detrimental effects mediated by Ang (1–7)/MasR pathway activation finally leading to further ACE2 cell membrane upregulation.
T106 21185-21420 Sentence denotes A condition that in COVID-19 can increase the probability of both SARS-CoV-2 entry and ACE2 shedding/systemic activity, finally generating positive feedback loops that might sustain SARS independently of viral infection (see Figure 2).
T107 21421-21738 Sentence denotes This hypothesis is supported by the observations that, in lung aspirates of acid- and/or spike-treated mice, Ang II and ACE2 are synergistically upregulated and cell surface downregulated (shed), respectively, suggesting their involvement in the increased lung microvascular permeability and pulmonary oedema [14,15].
T108 21739-21946 Sentence denotes Indeed, this condition might subsequently favour the diffusion, in neighbouring lung tissues and systemic circulation, of both (s)ACE2, Ang II and Ang (1–7), the Ang II-derived product of (s)ACE2 processing.
T109 21947-22136 Sentence denotes As already proposed, enhanced ACE2 shedding may locally reduce ACE2 activity in lung, however, it likely increases ACE2 systemic activity and subsequent production of circulating Ang (1–7).
T110 22137-22274 Sentence denotes Interestingly, Ang (1–7) has been also reported to promote eosinophil apoptosis in lungs and in bronco-alveolar lavage fluid (BALF) [40].
T111 22275-22546 Sentence denotes Moreover, Ang (1–7)/MasR axis inhibits allergic airway inflammation and eosinophil cell counts in the BALF of a murine model of asthma, indicating both that an impairment of ACE2 pathway may favour asthma and that ACE2 pathway activation can reduces asthma symptoms [68].
T112 22547-22778 Sentence denotes Moreover, a compound that mimics the Ang (1–7) actions has been shown to induce IL-10 upregulation via a MasR-dependent pathway in BALF [69] and IL-10 is thought to mediate anti-inflammatory effects of MasR pathway activation [70].
T113 22779-22899 Sentence denotes IL-10 secretion in mouse plasma was also induced by an AT2 receptor agonist and downstream nitric oxide signalling [71].
T114 22900-23093 Sentence denotes Increased IL-10 production (e.g., by T regulatory cells) is often associated with immune tolerance, which is the consequence of reduced number and function of specific immune compartments [72].
T115 23094-23454 Sentence denotes Indeed, IL-10 has been shown not only to suppress antigen-specific Th2-mediated immune responses including eosinophil expansion in allergic inflammation [72], but also to augment airway reactivity, suggesting that despite its potent anti-inflammatory activity, an excess of IL-10, as well as Ang (1–7), may contribute to the decline in pulmonary function [73].
T116 23455-23767 Sentence denotes Of note, IL-10 is one of the cytokines downstream ACE2 pathway [25] and is significantly upregulated in the most severe forms of COVID-19 [2,8,9], indicating an important correlation between ACE2/Ang (1–7) axis activation and IL-10 upregulation which might lead to eosinopaenia/lymphopaenia in COVID-19 patients.
T117 23768-23839 Sentence denotes Box 2 The reciprocal feedback-loop mechanisms of both arms of the RAS.
T118 23840-24172 Sentence denotes Similarly to hypoxic conditions, a strong correlation between the gene expression of ACE and that of ACE2 was also observed in human renal cortical biopsy specimen, suggesting a link between the two gene transcription, possibly related to the amount/excess of their substrates (Ang I and Ang II) and not exclusively to hypoxia [74].
T119 24173-24533 Sentence denotes A link that tends to maintain the balance of ACE/ACE2 ratio, but that may be disrupted by ACE inhibitors (ACEIs) or by Ang II type 1 receptor blockers (ARBs) which both have been shown to upregulate ACE2 mRNA expression in left ventricle of Lewis rats, possibly through two different mechanisms involving upregulation of Ang (1–7) or Ang II, respectively [75].
T120 24534-24799 Sentence denotes In this regard, in cardiac myocytes isolated from neonatal rats, Ang II significantly reduced ACE2 mRNA and its activity, effects blocked by ARBs, indicating that Ang II downregulates ACE2 expression/activity through an AT1R-dependent mechanism [76] (see Figure 1).
T121 24800-25154 Sentence denotes Moreover, in both cardiac myocytes and rat aortic vascular smooth muscle cells, Ang (1–7) prevented the Ang II-mediated reduction in ACE2 mRNA, an effect blocked by a selective MasR antagonist, D-Ala7-Ang-(1–7) (also known as A779), indicating that Ang (1–7) downregulates Ang II/AT1R signalling through a MasR-dependent mechanism [76,77] (see Figure 1).
T122 25155-25498 Sentence denotes Therefore, Ang (1–7) (as well as ACEIs and ARBs), preventing Ang II-mediated ACE2 downregulation, shift the Ang peptide balance in favour of Ang II metabolisation by ACE2, which, in turn, leads to further production of Ang (1–7), finally sustaining ACE2 transcription, membrane protein expression and eventually shedding and systemic activity.
T123 25499-25710 Sentence denotes Altogether these observations indicate a complex interplay of regulation between the two arms of the RAS in which feedback mechanisms of reciprocal (ACE/ACE2) pathway inhibition are involved at different levels:
T124 25711-25898 Sentence denotes Ang II/AT1 receptor mediates a negative feedback signal on the ACE2 expression/activity and Ang (1–7)/MasR mediated a negative feedback signal on the AT1 receptor activity (see Figure 1).
T125 25899-26129 Sentence denotes These reciprocal inhibitions in some cases (e.g., hypoxia/SARS-CoV-2 infection) can give rise to positive feedback loops that markedly shift the balance between Ang II/AT1R and the antagonist Ang (1–7)/MasR pathway (see Figure 1).
T126 26130-26427 Sentence denotes For example, under hypoxic conditions both arms of the RAS are upregulated and the presence of SARS-CoV-2 can affect Ang (1–7)/Ang II balance (which might be further influenced by ACEI/ARBs) by shifting it in favour of an increased ACE2 systemic activity, Ang (1–7) production and MasR activation.
T127 26428-26643 Sentence denotes This, in turn, can lead to further ACE2 cell membrane expression (increasing the probability of viral entry), which, after ACE2 shedding by binding to spike-SARS-CoV-2, ultimately establish a positive feedback loop.
T128 26645-26647 Sentence denotes 4.
T129 26648-26724 Sentence denotes COVID-19 Can Induce RAS-mediated Positive Feedback Loops at Different Levels
T130 26725-26900 Sentence denotes Intriguingly, the binding affinity of ACE2 to SARS-CoV-2 binding domain has been reported to be either equal to or 10- to 20-fold higher than ACE2 binding to SARS-CoV [27,32].
T131 26901-27002 Sentence denotes The affinity of spike protein for ACE2 has been shown to correlate with the severity of disease [24].
T132 27003-27276 Sentence denotes Although SARS-CoV produces more severe respiratory symptoms than NL63-CoV does, both viral receptor binding domains bind to ACE2 with similar affinity [78], indicating that SARS development is not related to the strength of binding affinity and depends on other mechanisms.
T133 27277-27515 Sentence denotes In contrast to SARS-CoV, NL63-CoV did not induce ADAM17/TACE-mediated both ACE2 shedding and TNF-α secretion [17], suggesting that increased cleavability of ACE2 receptor and possibly of S1-S2 boundary may be crucial for disease severity.
T134 27516-27687 Sentence denotes Indeed, the spike glycoprotein of SARS-CoV-2 but not of SARS-CoV, contains a furin-like cleavage site at the S1-S2 boundary which indicates an increased cleavability [13].
T135 27688-27842 Sentence denotes Of note, TNF-α and IL-1β were shown to both be upregulated in SARS-CoV-2 [2] and induce viral-independent ACE2 shedding from epithelial airway cells [16].
T136 27843-28116 Sentence denotes Moreover, viral-independent ACE2 surface release from epithelial cells was not only inducible by cytokines (e.g., TNF-α and IL-1β) but also constitutively and spontaneously produced when ACE2 surface expression was upregulated [16], for example upon IL-1β stimulation [56].
T137 28117-28265 Sentence denotes This suggests that systemic release of proinflammatory cytokines such as TNF-α and IL-1β can mediate an increase of sACE2 and its systemic activity.
T138 28266-28406 Sentence denotes Of note, activation of ADAM17/TACE metalloprotease was induced by SARS-CoV and necessary for efficient infection (and TNF-α secretion) [17].
T139 28407-28668 Sentence denotes Intriguingly, both SARS-CoV infection and concomitant TNF-α secretion were significantly attenuated not only by knock-down of ADAM17/TACE expression by siRNA but also by deletion of the ACE2 cytoplasmic tail which is responsible for ADAM17/TACE activation [17].
T140 28669-28839 Sentence denotes Altogether these observations suggest the possibility that SARS-CoV may induce a positive feedback loop leading to surface expression and shedding of both ACE2 and TNF-α.
T141 28840-29123 Sentence denotes Indeed, upon spike protein binding to ACE2, downstream pathway activation can sustain positive feedback loops at different levels (Figure 2):(1) SARS-CoV can induce IL-1β and TNF-α systemic secretion that can mediate viral-independent surface membrane ACE2 upregulation and shedding.
T142 29124-29305 Sentence denotes Of note, ACE2 shedding, on one hand, protects from viral infection but, on the other hand, increases circulating/systemic active sACE2, leading to its downstream pathway activation.
T143 29306-29677 Sentence denotes (2) Hypoxia in combination or not with hypercapnia can upregulate the activity of both arms of the renin–angiotensin system by inducing renin, ACE and ACE2 synthesis, which can increase expression of Ang I, Ang II, Ang (1–7), Ang (1–9), Ang (1–5) and the inactive metabolite bradykinin (1–7), but also membrane bound ACE2, finally giving more chances to SARS-CoV-2 entry.
T144 29678-29754 Sentence denotes (3) ACE2 can induce vasodilatative hypotensive effects by Ang II catabolism.
T145 29755-29898 Sentence denotes Hypotension can induce again renin and ACE upregulation finally providing further Ang II, as a ACE2 substrate for further Ang (1–7) production.
T146 29899-30214 Sentence denotes (4) Ang (1–7) antiproliferative and apoptotic effects, possibly in part through IL-10, may mediate eosinopaenia and lymphopaenia that, on one hand, reduce inflammatory responses but, on the other hand, impair immune system ability to counter virus infection, finally predisposing the organism to further infections.
T147 30215-30378 Sentence denotes Ang (1–7) immunosuppressive activity, mediated or not by IL-10, may also support the reduced ability to generate an effective immunization to SARS-CoV-2 infection.
T148 30379-30596 Sentence denotes (5) Ang (1–7)/MasR pathway can sustain ACE2 synthesis even in the presence of elevated concentrations of Ang II (such as in hypoxia), by inhibiting Ang II/AT1R-mediated down-modulation of ACE2 activity (see Figure 1).
T149 30597-30770 Sentence denotes (6) Ang (1–7)/MasR pathway can produce cardiac dysfunction and lung alteration leading to systemic hypoxia, which, in turn, upregulates the activity of both arms of the RAS.
T150 30771-31128 Sentence denotes (7) Although the ACE2 catalytic efficiency is 400-fold lower with Ang I than with Ang II [79], high concentration of circulating ACE2 may be able to produce significant increase of Ang (1–9) that, by binding AT2 receptors, can produce arteriolar microvascular thrombosis and local hypoxic conditions finally inducing local upregulation both arms of the RAS.
T151 31129-31476 Sentence denotes Finally, ACE2-loaded SARS-CoV-2 virions and S1-ACE2 complexes may impair both sACE2 proteolytic degradation by blood proteases and its renal excretion, therefore blunting the removal of its systemic enzymatic activity and indicating that circulating viral particles are dangerous even when they are not able to entry into the cells (see Figure 2).
T152 31477-31680 Sentence denotes On the one hand, ACE2 hypertranscription and consequent increase of membrane (m)ACE2 exposure induced by hypoxia/hypotension may facilitate SARS-CoV-2 entry and its lifecycle into mACE2 expressing cells.
T153 31681-31915 Sentence denotes On the other hand, the release of ACE2 from the cell membranes and its subsequent activity in the bloodstream and in local (lung/cardiac) extracellular fluids are likely critical steps in contributing to systemic disease pathogenesis.
T154 31916-32090 Sentence denotes Nevertheless, the same aetiological agent, SARS-CoV-2, can produce a variety of clinical syndromes, which involves several organs in relation to the subject’s predisposition.
T155 32091-32478 Sentence denotes Although in the present work I have supposed that most of the COVID-19 symptoms might derive from Ang (1–7), Ang II and Ang (1–9) peptide upregulation, the involvement of B1 receptor pathway suppression mediated by ACE2 metabolisation of des-Arg(9)-bradykinin to inactive bradykinin (1–7) or other ACE2-downstream peptides such as apelins, casomorphins and dynorphins cannot be rule out.
T156 32479-32661 Sentence denotes Based on the above observations, in order to block the RAS-induced positive feedback loops, different pharmacological targets can be hypothesized and pursued alone or in combination.
T157 32662-32715 Sentence denotes They will be discussed in the next section and Box 3.
T158 32716-32819 Sentence denotes Box 3 Possible targets of therapeutic intervention to inhibit the RAS-induced positive feedback loops.
T159 32820-33093 Sentence denotes Pharmacological inhibition of enzymes involved in both viral entry, such as TMPRSS2 and ADAM17, and the RAS function such as renin, ACE and ACE2 enzymatic activity or their downstream pathways are expected to stop positive feedback loops and their detrimental consequences.
T160 33094-33152 Sentence denotes Inhibition of TMPRSS2 and ADAM17 metalloprotease activity.
T161 33153-33448 Sentence denotes Inhibition of the serine protease TMPRSS2 (necessary for SARS-CoV-2 entry) by a clinically proven protease inhibitor has been recently suggested by Hoffmann and colleagues [13] and inhibition of ADAM17 enzymatic activity has been already proposed about ten years ago by Haga and colleagues [20].
T162 33449-33803 Sentence denotes Indeed, inhibition of ADAM17-mediated ACE2 shedding is expected to increase membrane ACE2 expression and therefore the probability of viral entry; nevertheless, in the early phases of the disease, inhibition of ACE2 circulating activity might be sufficient to inhibit the systemic RAS pathway upregulation and the development of severe forms of COVID-19.
T163 33804-34178 Sentence denotes It is, in fact, possible that maintenance/recovery of correct organismal immune responses, by preventing ACE2-mediated immune suppression, in concert with cellular adaptive immune responses mediated by apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like (APOBEC) systems [80] may anyway work to induce both an effective “immunization” and the viral eradication.
T164 34179-34214 Sentence denotes Inhibition of both arms of the RAS.
T165 34215-34412 Sentence denotes Among the inhibitors of the RAS pathways, different strategy can be pursued involving either ACE2 enzymatic activity or its upstream renin and ACE enzymatic activity or its downstream MasR pathway.
T166 34413-34639 Sentence denotes Inhibition of ACE2, ACE and renin enzymatic activities and their involvement in SARS-CoVs will be extensively discussed in the next sections, instead a brief description of MasR inhibition will be presented in the present Box.
T167 34640-34722 Sentence denotes Mas receptor pathway inhibition and side effects of using Mas receptor inhibitors.
T168 34723-34886 Sentence denotes A779 also known as D-Ala7-Ang-(1–7) and D-Pro7-Ang-(1–7) are two distinct MasR antagonists able to prevent Ang-(1–7)-mediated downstream activation in human cells.
T169 34887-35260 Sentence denotes The existence of several MasR subtypes has been suggested based on the differential capacity of the two MasR blockers to fully inhibit some biological actions of Ang-(1–7) [and perhaps of Ang (1–5), see Figure 1] [39,70]; therefore, differently from ACE2 enzymatic inhibitors, MasR antagonists should be administered in combinations, in order to inhibit ACE2 hyperactivity.
T170 35261-35451 Sentence denotes In human aortic smooth muscle cells, they have been shown to restore NADPH oxidase/NF-kB/iNOS inflammatory pathway induced by Ang II when it is inhibited by Ang (1–7) co-administration [81].
T171 35452-35830 Sentence denotes In mice studies a MasR blocker (A779) administered alone was not associated with systolic blood pressure alterations, and the hypotensive effect produced by rACE2 co-infused with Ang II was unaffected by A779 co-administration, indicating that the hypotensive activity of rACE2 mainly depended on Ang II degradation rather than on increase of Ang (1–7) and MasR activation [82].
T172 35831-36024 Sentence denotes In another report, spontaneously hypertensive rats (SHRs) that received A-779 alone for a total of two weeks did not significantly alter basal blood pressure and urinary protein excretion [83].
T173 36025-36297 Sentence denotes Moreover, in SHRs treated with A-779 in combination with Ang II, renal injury and interstitial infiltration of macrophages and T cells were surprisingly reduced as compared with SHRs treated with Ang II alone, suggesting a safe use of A-779 drug in in vivo infusions [83].
T174 36298-36454 Sentence denotes Another report showed that infusion of A-779 alone for 7 days did not produce a significant effect neither on blood pressure nor on heart rate in SHRs [84].
T175 36455-36671 Sentence denotes In a rat model of cardiac arrhythmia, administration of A-779 alone did not cause any significant alteration in the number of arrhythmic events, confirming that A-779 can be safely delivered to rodents in vivo. [85].
T176 36672-37022 Sentence denotes Although MasR antagonists has been shown to be safe in acute and chronic in vivo studies either with mice or rats, there are no data on administration in humans and the existence of different MasR subtypes in the vasculature require combinations of MasR antagonists to inhibit an excess of ACE2 activity as for example may occur in COVID-19 patients.
T177 37024-37026 Sentence denotes 5.
T178 37027-37112 Sentence denotes Mechanism of Action and Potential Risk of Using RAS Pathway Inhibitors Targeting ACE2
T179 37114-37118 Sentence denotes 5.1.
T180 37119-37148 Sentence denotes ACE2 (and ACE) Hyperactivity:
T181 37149-37179 Sentence denotes Is It a Matter of (Free) Zinc?
T182 37180-37275 Sentence denotes ACE2 and ACE are two zinc metalloprotease that function differently despite their similarities.
T183 37276-37466 Sentence denotes ACE2 is a monocarboxypeptidase (cleaves a C-terminal single amino acid from its substrate), whereas ACE is a dipeptidylpeptidase (releases a C-terminal dipeptide from its substrate) [86,87].
T184 37467-37773 Sentence denotes ACE2 has a substrate preference for hydrolysis between proline and a hydrophobic or basic C-terminal residue [79,86,87] and acts not only on the RAS and bradykinin peptides but also on the C-terminus of the apelin, casomorphin dynorphin peptides [79], possibly inhibiting Apelin-13 hypotensive action [44].
T185 37774-37890 Sentence denotes It is expressed in the heart, kidneys, liver, colon, small intestine, lung, brain and testes [39,44,45,46,76,77,87].
T186 37891-38100 Sentence denotes Among the tissues expressing ACE2 there are cardiomyocytes, endothelium, alveolar type II cells, ciliated airway cells, vascular smooth muscle cells and testicular Leydig cells [14,39,44,45,46,76,77,87,88,89].
T187 38101-38397 Sentence denotes ACE2 is present on the apical surface of epithelial cells of renal tubules, lung alveoli and vascular endothelia, in these last cells the production of Ang (1–7) induces autocrine activation of MasR axis leading to NOS-mediated vasodilation and consequently hypotension [14,44,45,46,86,87,88,89].
T188 38398-38583 Sentence denotes ACE2, as well as ACE, is a zinc metalloprotease that can be inhibited by zinc chelating EDTA and activated by high concentrations of chloride or fluoride anions and zinc cation [79,90].
T189 38584-38648 Sentence denotes Indeed, both enzymes have chloride- and zinc-binding sites [90].
T190 38649-38773 Sentence denotes It is conceivable that these sites are responsible for the anion and zinc activation effect in both homologous enzymes [90].
T191 38774-39032 Sentence denotes However, the presence of chloride ions increases Ang I cleavage by ACE and ACE2 (increasing both Ang II and Ang (1–9)) and decreases Ang II cleavage by ACE2, suggesting that chloride induces specific ACE2 conformational changes in its active site (see [44]).
T192 39033-39203 Sentence denotes To this regard, in plasma samples of COVID–19 patients, chloride range is usually normal or slightly higher (99.6–107.0 mmol/L) than normal values (96.–106.0 mmol/L) [5].
T193 39204-39290 Sentence denotes Unfortunately, I was not able to find plasma zinc concentrations in COVID-19 patients.
T194 39291-39410 Sentence denotes Zinc is involved in several cellular activities and its systemic concentration is tightly regulated by several factors.
T195 39411-40011 Sentence denotes Of interest, the major transporter/reservoir of zinc in plasma is albumin [91], a protein that was detected at significantly low concentrations in SARS-CoV-2 as well as severe adult respiratory distress syndrome (ARDS, a COVID-19-like disease) (usually < 3.5 g/dL, normal range 3.5–5.4) and inflammatory bowel disease (IBD, a disease with increased ACE2 activity) [6,8,66,92] Since most of zinc in plasma is sequestered by albumin, the total amount of plasma zinc mostly depends on albumin concentration and even small changes in albumin’s capacity for zinc binding may have significant consequences.
T196 40012-40234 Sentence denotes To this regard, reduced concentrations of plasma albumin is believed to increase plasma levels of free zinc, while reducing the total plasma zinc concentrations [91], a condition that was observed in ARDS patients [93,94].
T197 40235-40377 Sentence denotes Indeed, albumin can potentially deplete free bioavailable forms of zinc; vice versa, hypoalbuminaemia may increase free zinc levels in plasma.
T198 40378-40513 Sentence denotes Therefore, some ARDS patients with low levels of both total zinc and albumin might have rather higher than lower free zinc levels [93].
T199 40514-40728 Sentence denotes The free zinc concentration, which describes the fraction of zinc that is loosely bound and easily exchangeable, represents the highly bioavailable (and toxic) part of plasma zinc but it is not clinically detected.
T200 40729-40809 Sentence denotes To that end, zinc/albumin ratio might be a surrogate marker of free zinc levels.
T201 40810-40949 Sentence denotes Indeed, only recently it was described a fluorescence-based method for determining the free zinc concentration in human serum samples [95].
T202 40950-41073 Sentence denotes With this method it was shown that free zinc concentration in sera from females was significantly lower than in males [95].
T203 41074-41223 Sentence denotes Moreover, free zinc concentration did correlate neither with total serum concentrations of zinc (or other metal ions such as iron) nor with age [95].
T204 41224-41447 Sentence denotes Notably, increased plasma zinc bioavailability consequent to reduced albumin levels induces zinc import into cells and likely increases the cellular functions associated to cellular zinc concentrations such as ACE and ACE2.
T205 41448-41634 Sentence denotes Indeed, enzymatic activity of both enzymes seems significantly upregulated in ARDS patients as detected by analysis of Ang peptide concentrations in plasma (see Box later in ARDS topic).
T206 41635-41873 Sentence denotes In addition, serum albumin levels in COVID-19 were usually very low (in severe forms is usually < 3.1 g/dL) [6,8], raising the possibility of a negative correlation between albumin concentration in plasma and increase of the RAS activity.
T207 41874-42196 Sentence denotes In line with these hypotheses, both asthmatic/allergic disease patients and chronic kidney disease patients without a history of cardiovascular disease, which are protected from developing COVID-19, showed a significant decrease in both circulating zinc levels and ACE2 activity as compared to normal values [96,97,98,99].
T208 42197-42503 Sentence denotes Interestingly, chronic renal disease patients with low zinc levels had normal concentrations of albumin but higher urinary zinc excretion than healthy controls [97], suggesting that low ACE2 activity in chronic renal diseases (and protection from SARS) might derive from a higher free Zn2+ renal excretion.
T209 42504-42641 Sentence denotes A similar mechanism mediated by a reduction of extracellular levels of free Zn2+ might be hypothesised for asthma patients, as well [98].
T210 42642-42839 Sentence denotes Unfortunately, I could not find information on plasma albumin concentrations for asthma patients; nevertheless, we might suppose that in these patients the albumin concentration is in normal range.
T211 42840-43073 Sentence denotes Intriguingly, inhalation exposure to ZnCl2/ZnO/hexachloroethane (the main ingredients in smoke bombs) induces both elevated plasma levels of zinc and ARDS with clinical pictures that strongly resemble those of COVID-19 [100,101,102].
T212 43074-43309 Sentence denotes Since both ACE2 and ACE enzymes are activated by high concentrations of chloride and zinc ions [79,90], it is possible to hypothesise an activation of both arms of the RAS in ARDS induced by smoke bombs as well as in COVID-19 patients.
T213 43310-43561 Sentence denotes In addition, metal fume fever, a flu-like syndrome caused by inhalation of welding fumes (mainly containing zinc) can be a predictor for the development of respiratory symptoms and welders have an increased pneumonia and cardiovascular risk [103,104].
T214 43562-43834 Sentence denotes In this regard, metal fume fever has been shown to produce fever, fatigue, muscle ache, cough, dyspnea, and an increase of several cytokines including IL-1β, IL-6, IL-8 and TNF-α [103], symptoms and cytokines that have already been described for COVID-19 patients [2,8,9].
T215 43835-44020 Sentence denotes Notably, TNF-α was upregulated early while IL-6 and IL-8 increased later, suggesting a subsequent involvement of these latter cytokines in response to inhalation of welding fumes [103].
T216 44021-44189 Sentence denotes Moreover, elevated levels of zinc have been shown not only to stimulate pro-inflammatory cytokine secretion by monocytes, but also inhibit T cell functions (see [102]).
T217 44190-44552 Sentence denotes Zinc supplementation that has also been proposed for COVID-19 treatment [105,106,107], is able to suppress allogeneic immune response (see [102]) and incubation of blood cells with welding fume particles resulted in a considerable increase not only of pro-inflammatory cytokines (including IL-1β, IL-6, IL-8, TNF-α) but also the tolerogenic cytokine IL-10 [104].
T218 44553-44881 Sentence denotes Similarly, in pulmonary arterial hypertension (PAH) as well as SARS-CoV, both arms of the inflammatory system (namely IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, IL-12 and TNF-α) have been shown to be upregulated [108,109,110], suggesting a common systemic pathway of activation in welding syndrome, ARDS, PAH and SARS-CoV infections.
T219 44882-45051 Sentence denotes Finally, the correlations between zinc exposure (metal fume) and cytokine storm [103,104] suggests a possible link between free zinc increase and these type of diseases.
T220 45052-45232 Sentence denotes More information on systemic zinc homeostasis and multiorgan effects of elevated levels of extracellular free zinc (such as in subjects inhaling ZnCl2 smoke) is available in Box 4.
T221 45233-45335 Sentence denotes Box 4 Systemic zinc homeostasis and multiorgan effects of elevated levels of extracellular free zinc.
T222 45336-45577 Sentence denotes Zinc absorption occurs throughout the gastrointestinal tract into enterocytes by zinc transporters of the Zrt- and Irt-like protein (ZIP) family that take up Zn2+, but also Cu2+ and Fe2+ ions, both of which can inhibit zinc absorption [111].
T223 45578-45875 Sentence denotes The bioavailability of zinc is affected by several factors among them the amount of zinc in food, its chemical form (from very low availability, e.g., zinc oxide, to comparatively high, e.g., zinc chloride salt) and its binding to other (intestinal absorbed or non-absorbed) food components [111].
T224 45876-46080 Sentence denotes For example, phytates (components present in foods like rice, cereals and corn) and folic acid can form insoluble complexes with zinc that decrease zinc absorption and increase fecal zinc excretion [111].
T225 46081-46317 Sentence denotes On the other hand, Zn2+ can form complexes with most natural amino acids (AA) that for example can come from digested proteins; each Zn2+ can be coordinated with the amine groups and carboxylate anions of two AAs (a molar ratio of 1:2).
T226 46318-46592 Sentence denotes Interestingly, in an in vitro model, the formulation of either ZnCl2 salt or Zn-AA complexes were absorbed by enterocytes and zinc was released on the opposite side of the enterocyte membrane, thus mimicking the intestinal absorption and release into the blood stream [111].
T227 46593-46724 Sentence denotes It is therefore conceivable that zinc chelates of AA, as well as zinc salts, may participate in bioavailability and uptake of zinc.
T228 46725-47011 Sentence denotes The uptake of zinc-AA complexes by AA transporters of human enterocytes suggests that B0AT1 neutral AA transporter associated with ACE2 [28] might also be involved in zinc-AA uptake (a similar mechanism might be supposable for insulin biosynthesis/secretion in pancreatic β cells [91]).
T229 47012-47163 Sentence denotes Indeed, a recycling of zinc-AAs, possibly supplied by membrane bound ACE2 monocarboxypeptidase cleavage, for ACE2 synthesis could be also hypothesised.
T230 47164-47381 Sentence denotes Plasma zinc concentration is mainly regulated through a balance between intestinal absorption and renal excretion involving specific mechanisms sensitive to both dietary zinc availability and its cellular utilization.
T231 47382-47508 Sentence denotes The majority of Zn2+ in blood binds to serum albumin, which represents the major zinc transporter/reservoir protein in plasma.
T232 47509-47768 Sentence denotes On the other hand, labile-bound pool of Zn2+ labile complexes (e.g., of AA) and free Zn2+ are the biologically available forms of zinc for cellular internalization and/or enzymatic activities (0.1–1% of the total zinc in blood plasma under normal conditions).
T233 47769-47952 Sentence denotes Free Zn2+ is subsequently accumulated by endothelial cells and zinc uptake and release by endothelial cells is the crucial step for redistribution of Zn2+ from plasma to tissues [91].
T234 47953-48132 Sentence denotes Zinc is considered a relatively nontoxic metal; however, several data report that excessive free extracellular zinc is toxic and induce apoptosis in different cell types [91,102].
T235 48133-48466 Sentence denotes Plasma excess of free Zn2+ is uptaken by ZIP transporters on the cell surface of each cells in contact with plasma (including immune cells, endothelial cells, neurons and cardiomyocytes), leading to increase of intracellular zinc that can modulate zinc associated cellular functions in both physiological and pathological conditions.
T236 48467-48897 Sentence denotes Indeed, zinc is an important mediator/messenger involved in several cellular activities and the shift of zinc from plasma to cells may be significant for both normal physiological processes including energy metabolism, blood coagulation, and zinc signalling, and a range of disease states, including neurodegenerative and cardiovascular diseases, metabolic syndrome, inflammation, endothelial stress, diabetes and thrombosis [91].
T237 48898-49124 Sentence denotes For example, excess zinc intake has been shown to contribute to both amyloid beta-peptide plaque formation in Alzheimer’s disease and cardiac dysfunction, indicating that free zinc ion may be much more toxic than thought [91].
T238 49125-49401 Sentence denotes It has been reported that Alzheimer and other neurodegenerative disease patients show elevated levels not only of Zn2+ but also of other divalent metals such as Fe2+ and Cu2+ [112], suggesting a possible link between the increase metal ions and saturation of ZIP transporters.
T239 49402-49615 Sentence denotes On the other hand, increased plasma ferritin levels (such as in COVID-19 [2,3,6]) might reduce free Fe2+ and its “competition” with Zn2+ for ZIP transporters, finally increasing cellular zinc uptake and functions.
T240 49616-49755 Sentence denotes To this regard, EDTA metal chelator has been shown to protect from neural cell death and it was tested in neurodegenerative diseases [102].
T241 49756-49938 Sentence denotes Of interest, plasma albumin acts as a transport protein for both metal ions such as zinc and hydrophobic molecules such as free fatty acid (FFA) to allow their systemic distribution.
T242 49939-50120 Sentence denotes Indeed, albumin is well beyond a mere carrier of metal ions and hydrophobic molecules, and by binding of these different molecules mediates their crosstalk and bioavailability [91].
T243 50121-50233 Sentence denotes To this regard, one particularly intriguing allosteric link exists between FFA and zinc binding to albumin [91].
T244 50234-50439 Sentence denotes When FFAs with ten or more carbon atoms bind to albumin causes the release of Zn2+, suggesting a possible link between dyslipidemia and toxic effects mediated by consequent increase of free zinc in plasma.
T245 50440-50628 Sentence denotes For example, endothelial stress and activation and pro-inflammatory action of FFAs may be mediated by their effects on free zinc release from albumin and its consequent efflux from plasma.
T246 50629-50799 Sentence denotes Different studies have suggested a role of albumin to inhibit interaction of free Zn2+ with amyloid beta-peptides and combat plaque formation in Alzheimer’s disease [91].
T247 50800-50913 Sentence denotes Zn2+ has also been shown to promote clot stability by binding to fibrinogen and inhibiting heparin activity [91].
T248 50914-51035 Sentence denotes An evidence that has suggested a possible positive correlation between increased levels of FFAs and thrombotic risk [91].
T249 51036-51265 Sentence denotes In addition, physiological conditions associated with elevated plasma FFAs, such as physical exercise, can also produce an increased plasma level of free zinc and its downstream physiological events (e.g., activation of the RAS).
T250 51266-51434 Sentence denotes On the other hand, reduced concentrations of plasma albumin (such as IBD, ARDS and COVID-19) will induce elevated plasma levels of both free FFAs and bioavailable zinc.
T251 51435-51597 Sentence denotes Intriguingly, ARDS is induced after inhalation exposure to ZnCl2/ZnO/hexachloroethane, the main ingredients in smoke bombs used for crowd dispersal [100,101,102].
T252 51598-51715 Sentence denotes To this regard, soldiers that breathed smoke-bomb fumes have been shown to quickly or slowly develope ARDS [100,101].
T253 51716-51898 Sentence denotes Interestingly, a patient who had the highest level of serum zinc rapidly developed ARDS that leads to death from multiorgan failure (including respiratory and hepatic failure) [100].
T254 51899-52186 Sentence denotes Instead, a slow progressive clinical course was associated with a significant increase of plasma zinc concentration that negatively correlated with pulmonary and liver function [100], finally leading to death for severe respiratory failure three to five weeks after inhalation [100,101].
T255 52187-52287 Sentence denotes At autopsy diffuse microvascular obliteration and marked endothelial cell injury was apparent [101].
T256 52288-52480 Sentence denotes Widespread occlusion of the pulmonary arteries may contribute to the development of acute pulmonary hypertension and extensive interstitial and intra-alveolar fibrosis was also observed [101].
T257 52481-52693 Sentence denotes Other soldiers wearing gas masks, immediately developed severe coughing and dyspnea, and slowly improved their lung function (only twelve months after exposure their lung function tests were nearly normal) [101].
T258 52694-52778 Sentence denotes All clinical conditions that strongly resemble those described in COVID-19 patients.
T259 52780-52784 Sentence denotes 5.2.
T260 52785-52851 Sentence denotes Safety and Efficacy Concerns of MLN4760 and Dx600 ACE2 Inhibitors.
T261 52852-52991 Sentence denotes It is known that the catalytic cleft of ACE2 consists of two peptidase subdomains: one membrane-distal and the other one membrane-proximal.
T262 52992-53112 Sentence denotes Their weak interactions are consistent with the ability to transition from open to the closed ACE2 conformation [28,90].
T263 53113-53388 Sentence denotes Indeed, the two subdomains undergo a large hinge-bending motion in which membrane-proximal subdomain remains almost unchanged, while membrane-distal subdomain moves to close the distance between the two subdomains, mimicking the opening/closing movement of a clam shell [90].
T264 53389-53679 Sentence denotes ACE2 open conformation likely reflects free state of the enzyme available to catch substrates (or inhibitors), then, when the ACE2 receptor binds to a substrate, the membrane-distal subdomain closes around the substrate (or the inhibitor), finally performing the enzymatic activity [24,90].
T265 53680-53860 Sentence denotes Interestingly, in cryo–electron microscopy structures of full-length human ACE2, only the closed/substrate-bound conformation of ACE2 was observed in the spike-ACE2 complexes [28].
T266 53861-54105 Sentence denotes Since human ACE2 is assembled on cell surface as a homodimer [28], binding of the spike protein trimer onto ACE2 dimer suggests simultaneous binding of two spike protein trimers to substrate-bound conformer of ACE2 homodimer on plasma membrane.
T267 54106-54362 Sentence denotes The spike binding sites on ACE2 homodimer are localized above the membrane-distal peptidase subdomain of each ACE2 monomer, nevertheless neither ACE2 shedding nor ACE2 binding to spike proteins have been shown to inhibit ACE2 enzymatic activity [16,17,24].
T268 54363-54630 Sentence denotes On the other hand, the S-protein-binding region of membrane-distal ACE2 subdomain is not significantly perturbed by the receptor conformational changes and maintains the ability to associate with soluble spike proteins independently on open/closed conformations [24].
T269 54631-54833 Sentence denotes Interestingly, an ACE2 specific inhibitor (MLN-4760) has been shown to induce the closed (inhibitor-bound) ACE2 structure [90] and to retain its inhibitory effects on sACE2 bound to spike proteins [24].
T270 54834-55034 Sentence denotes MLN4760 is a potent and selective human ACE2 inhibitor (IC50 = 0.44 nM against soluble human ACE2) whose synthesis produces a racemic mixture of two diastereomers that showed 75:25 ratio for Isomer A:
T271 55035-55144 Sentence denotes Isomer B [113,114] and the purified isomer B is the isomer commercially available from Merck Millipore [114].
T272 55145-55330 Sentence denotes Testing MLN-4760 racemic mixture and its isomers, it was observed a concentration-dependent inhibition of recombinant human (rh)ACE or rhACE2 activities with all three inhibitors [114].
T273 55331-55681 Sentence denotes The isomer B was less selective (near minimal-maximal rhACE inhibition range 10−6M-10−4M) than the racemate or the isomer A (near minimal-maximal rhACE inhibition range 10−6M-10−2M) and less effective (near maximal rhACE2 inhibition at 10−7M) than the racemate or the isomer A (near maximal rhACE2 inhibition at 10−8 M) for rhACE2 versus rhACE [114].
T274 55682-56048 Sentence denotes Moreover, all three inhibitors exerted a significantly higher inhibitory activity against soluble than membrane-bound forms of (m)ACE2 (near maximal mACE2 inhibition at 10−6M), being the isomer B more selective and effective than the racemate or the isomer A for mACE2 vs. mACE expressed on the surface of mononuclear cells (or CD34 hematopoietic progenitors) [114].
T275 56049-56148 Sentence denotes A second ACE2 inhibitor, Dx600, produced similar results to those obtained with the isomer B [114].
T276 56149-56315 Sentence denotes Another study evaluated the inhibitory activity of both MLN-4760 and DX600 (either the linear conformational form or the disulfide bridged cyclic variant) inhibitors.
T277 56316-56527 Sentence denotes In this report, the experiments were performed at pH 6.5 [115], a pH at which rhACE2 proteolysis operates at maximal activity [79] and a condition that resembles hypercapnic acidosis which may occur during SARS.
T278 56528-56864 Sentence denotes MLN-4760 was still able to strongly and specifically inhibit rhACE2 activity (near maximal inhibition at 10−8 M), preventing rhACE2-driven Ang II degradation into Ang (1–7), whereas DX600 (either linear or cyclic variant) inhibits rhACE2 at relatively higher concentration (near maximal inhibition at 10−6 M–10−7 M, respectively) [115].
T279 56865-57009 Sentence denotes Altogether these data indicate that the racemate or the isomer A are more effective in inhibiting soluble forms of ACE2 than isomer B and Dx600.
T280 57010-57363 Sentence denotes Therefore, these inhibitors at opportune (low) concentrations are expected to preferentially reduce systemic sACE2 activity, while preserving the ACE2 activity of (local) membrane-associated forms of ACE2, knowing that catalytic activity of circulating ACE2 was undetectable in human plasma of healthy subjects due to an endogenous ACE2 inhibitor [116].
T281 57364-57719 Sentence denotes Since MLN-4760 inhibitor promotes the closed ACE2 conformation [90] which is the preferential conformer for virus binding [28], MLN-4760 is expected to not prevent viral entry; nevertheless, its inhibitory function on ACE2 pathway might work on the positive feedback loops (above described) that ultimately favour ACE2 membrane expression and viral entry.
T282 57720-57837 Sentence denotes A potential risk factor of inhibiting the Ang II metabolization into Ang 1–7 could be the increase of blood pressure.
T283 57838-58347 Sentence denotes Although ACE2 pathway inhibition might lead to hypertensive effects, treatment with MLN-4760 for 4-5 weeks had no effect on blood pressure when administered 10 mg/kg/day in drinking water in wild type mice [117] nor in male (mRen2)27 transgenic hypertensive rats (administered 30 mg/kg/day subcutaneously via mini-osmotic pumps) [118], suggesting that hypertensive activity mediated by ACE2 inhibition is promptly balanced by compensatory mechanisms either in normal or hypertensive blood pressure conditions.
T284 58348-58553 Sentence denotes In addition, injections of MLN4760 into the nucleus tractus solitarii has been shown to reduce the baroreceptor reflex in rats, suggesting a role for ACE2 in controlling a reflex bradycardia (see [39,44]).
T285 58554-58788 Sentence denotes Finally, chronic inhibition of ACE2 with MLN-4760 led to increase of ACE, albuminuria and glomerular injury in streptozotocin-induced diabetic mice, indicating a possible adverse effect of the inhibitor in a diabetic background [119].
T286 58789-58962 Sentence denotes Extensive experiments have been also performed with DX600, a specific peptide ACE2 inhibitor that exhibited a mixed competitive and non-competitive type of inhibition [120].
T287 58963-59060 Sentence denotes Actually, several reports describing Dx600 inhibitor administration in mice suggest its safe use.
T288 59061-59341 Sentence denotes Of interest, a report described its (safe) use alone (1 mg/kg per day) by nasal inhalation for 3 days in a mouse model of endotoxin-induced lung inflammation [121]; however, this inhibitor is less efficacious than MLN-4760 in inhibiting the soluble forms of human rACE2 [114,115].
T289 59342-59538 Sentence denotes Altogether these reports on administration of ACE2 inhibitors do not reveal significant adverse impacts or mortality in experimental animals, which suggests their safety in chronic administration.
T290 59539-59638 Sentence denotes This was also confirmed in human clinical trials with MLN-4760 (clinical name: ORE1001, see later).
T291 59639-60158 Sentence denotes Of interest, a report showed that on day 28 post-myocardial infarction, adult male Sprague-Dawley rats that had received MLN-4760 (also called C16) 25 mg/mL/day by daily intraperitoneal injection (as a solution of 42 mg/mL in distilled water) tended to have lower left ventricular pulse pressure, mean arterial pressures and left ventricular relaxation time constant-Tau compared to untreated group (see table 2 of the paper) [52], suggesting a possible protective role of ACE2 inhibition in post-myocardial infarction.
T292 60159-60439 Sentence denotes Therefore, MLN-4760 might be helpful not only for COVID-19 but also in targeted therapies for pathologies correlated with an excessive increase of ACE2 activity that may involve heart, lung, liver, colon or other tissues/organs expressing ACE2 such as blood and endothelial cells.
T293 60440-60666 Sentence denotes As an example, GL1001 (old name of MLN-4760) showed to produce an anti-inflammatory activity in a mouse model of colitis [122], highlighting the importance of the yin-yang balance of ACE/ACE2 pathways (“in medio stat virtus”).
T294 60668-60672 Sentence denotes 5.3.
T295 60673-60721 Sentence denotes Safety and Efficacy Concerns of Chelating Agents
T296 60722-60939 Sentence denotes Based on ACE2 mechanism of action, there are alternative ways to inhibit ACE2 (and ACE), for example concentration of cation/anion might also targets of intervention to inhibit the zinc metalloprotease ACE2 (and ACE).
T297 60940-61037 Sentence denotes In this regard, EDTA, a cation chelator, has been shown to be able to inhibit ACE2 activity [79].
T298 61038-61332 Sentence denotes Of interest, EDTA binds with 106- and 102-fold higher affinity to Zn2+ than to Ca2+ and Fe2+, respectively [123], and in plasma, free Ca2+ concentration (1.05–1.30 mmol/L) is “only” about 103-fold higher than free Zn2+ (0.1–2.0 µmol/L), while majority of iron in plasma is bound to transferrin.
T299 61333-61445 Sentence denotes As a consequence, the iron concentration in plasma of healthy subjects is very low on the order of 10−18M [112].
T300 61446-61753 Sentence denotes Among the essential metal ions present in the organisms, the specific affinity of EDTA for systemic Zn2+ in physiologic conditions is highlighted by the evidence that prolonged treatment with CaNa2EDTA results in specific zinc depletion that is believed to mediate the teratogenic effects of the drug [123].
T301 61754-62083 Sentence denotes As already mentioned, zinc is an important mediator/messenger involved in several cellular activities and excess of free zinc has been shown to be toxic (see also Box 4); however, zinc deficiency has also detrimental effects on growth, neuronal development, and immunity, and in severe cases its consequences can be deadly [102].
T302 62084-62276 Sentence denotes For these reasons, treatments with CaNa2EDTA require a careful monitoring of the patient for the therapeutic effects as well as possible complications, so as to titrate the appropriate dosage.
T303 62277-62382 Sentence denotes CaNa2EDTA was approved by FDA in chelation therapy for lowering blood lead levels a long time ago (1953).
T304 62383-62516 Sentence denotes Then, different (commercially available) iron chelating agents, expected to work in chelating zinc ion as well, were approved by FDA.
T305 62517-62650 Sentence denotes Chelation therapy comprises intravenous or oral administration of chelating agents that remove metal ions such as zinc from the body.
T306 62651-62748 Sentence denotes Cells synthesising high amounts of ACE or ACE2 needs of high amounts of bioavailable (free) zinc.
T307 62749-62891 Sentence denotes Therefore, it is conceivable that plasma levels of free zinc may influence not only ACE and ACE2 activities but also their cellular synthesis.
T308 62892-63023 Sentence denotes Indeed, both ACE and ACE2 synthesis might be particularly sensitive to reduction of free zinc levels in case of their upregulation.
T309 63024-63216 Sentence denotes In addition, metal chelating agents, by limiting the availability of free zinc to cells, might have effects on both ACE2/ACE synthesis and conformation (when assembled on the plasma membrane).
T310 63217-63514 Sentence denotes Indeed, the closed conformer of ACE2 homodimer that is the preferential conformation for virus binding [28], needs the presence of both zinc and substrate/inhibitor in the catalytic site [90], suggesting that zinc chelation (differently from MLN-4760) might also inhibit ACE2-mediated viral entry.
T311 63515-63761 Sentence denotes Intriguingly, chloroquine has been shown to specifically enhance zinc uptake and its accumulation/sequestration in the lysosomes [124], raising the possibility that it might work on COVID-19 patients by reducing zinc recycling and zinc functions.
T312 63762-63971 Sentence denotes As already mentioned, free Zn2+ promotes clot stability by binding to fibrinogen (see Box 4 and [91]) and chloroquine has been shown to have an anti-thrombotic activity by inhibiting platelet activation [125].
T313 63972-64352 Sentence denotes To this regard, upon platelet activation the release of Zn2+ store from their secretory granules has been shown to participate to the pro-coagulant activity in platelet-dependent fibrin formation [126], suggesting that an elevated free Zn2+ concentration might occur and contribute to thrombotic predisposition in COVID-19 patients, a phenomenon possibly countered by chloroquine.
T314 64353-64594 Sentence denotes For all of the above reasons, cation chelating agents, administered alone or in combination with other therapies, might be effective to counter COVID-19 infection, in particular when, induced by hypoxia, both arms of the RAS are upregulated.
T315 64595-64642 Sentence denotes A scenario that would deserve an investigation.
T316 64643-65005 Sentence denotes However, some formulations of metal chelating agents carry a black box warning because they may cause serious and fatal renal toxicity and failure, hepatic toxicity and failure, gastrointestinal haemorrhage, arrhythmias, tetany, hypocalcaemia, hypotension, convulsions, respiratory arrest, and agranulocytosis that can lead to serious infections and death [123].
T317 65006-65173 Sentence denotes For the sake of completeness, besides renal toxicity linked to the route of drug excretion, EDTA has been shown to be effective in chronic renal artery diseases [123].
T318 65174-65264 Sentence denotes Finally, for its teratogenic effects, the drug is also contraindicated in pregnancy [123].
T319 65265-65487 Sentence denotes As a result, treatments with metal chelating agents require close patient monitoring, including laboratory tests of renal and hepatic function, and absolute neutrophil count should be monitored before and during treatment.
T320 65488-65559 Sentence denotes Alternative ways of RAS pathway inhibition are also described in Box 5.
T321 65560-65610 Sentence denotes Box 5 Alternative ways of RAS pathway inhibition.
T322 65611-65718 Sentence denotes Of interest, a small cationic inhibitor of ACE2 (but not of ACE) has been detected in plasma samples [116].
T323 65719-65973 Sentence denotes The endogenous inhibitor might play a compensatory fine-control (within a threshold limit) for normal fluctuation of ACE2 protein in plasma and it has been hypothesized to be a basic AA or a small basic peptide able to compete with ACE2 substrates [116].
T324 65974-66081 Sentence denotes I have already mentioned that AA can chelate zinc forming labile zinc complexes of amino acids (see Box 4).
T325 66082-66267 Sentence denotes It is therefore possible that a basic AA or a small basic peptide capable to specifically accommodate into the catalytic site of ACE2, but into that of ACE, could inhibit ACE2 activity.
T326 66268-66432 Sentence denotes Indeed, despite the similarities, ACE and ACE2 possess different substrate specificity that depends on the smaller ACE2 binding pocket compared to that of ACE [90].
T327 66433-66609 Sentence denotes This specific aspect might determine the specificity for a specific basic amino acid or molecule that is able to accommodate into the catalytic pocket of ACE2 and bind to zinc.
T328 66610-66770 Sentence denotes Among the possible endogenous ACE2 inhibitors, agmatine, decarboxylated arginine, has a chemical structure that resembles that of an ACE2 inhibitor, NAAE [127].
T329 66771-66947 Sentence denotes NAAE is a small molecule that had demonstrated an anti-SARS-CoV activity, by acting on both ACE2 catalytic activity and ACE2 binding domain for spike protein of SARS-CoV [127].
T330 66948-66996 Sentence denotes Unfortunately, NAAE has never been used in vivo.
T331 66997-67287 Sentence denotes Indeed, NAAE is a weak ACE2 inhibitor, it is in fact more than a thousand-fold less potent than MLN-4760; however, if agmatine will be proven to have ACE2 inhibitory activity, it might be helpful to prevent the trigger of the positive feedback loops in the first mild phases of the disease.
T332 67288-67410 Sentence denotes Indeed, it has an important role in down-regulating NO synthesis reducing NO overproduction by different mechanisms [128].
T333 67411-67572 Sentence denotes Of note, NOS pathway has been shown to be upregulated by both Ang (1–7)/MasR and Ang (1–9)/AT2 receptor pathways that are downstream ACE2 activity [38,39,41,43].
T334 67573-67764 Sentence denotes Moreover, agmatine has a regulated plasma concentration in the range of 20-80 ng/mL and the use of dietary agmatine has been shown to be safe and effective in reducing neuropathic pain [129].
T335 67765-67840 Sentence denotes Moreover, agmatine sulfate is regularly taken as a bodybuilding supplement.
T336 67841-68051 Sentence denotes Among natural metal-chelating agents, phytates and folic acid are two chelating agents from vegetables that might reduce zinc intestinal absorption and possibly its systemic concentration (see Box 4 and [111]).
T337 68052-68204 Sentence denotes Similarly, nicotianamine that is extracted from plants (soybean) is a low-molecular weight metal chelator with high affinity for divalent metal cations.
T338 68205-68308 Sentence denotes Nicotianamine has been shown to inhibit the activity of both zinc metalloproteases, ACE2 and ACE [130].
T339 68309-68390 Sentence denotes In addition, zeolites might also be effective in reducing free zinc availability.
T340 68391-68519 Sentence denotes Zeolites are a group of aluminosilicate minerals with crystalline microporous structure that are originated from volcanic rocks.
T341 68520-68691 Sentence denotes Their molecular structure generates cavities that allow high absorbency capacity for a wide range of charged elements such as water, heavy metals, cations and many toxins.
T342 68692-68792 Sentence denotes Clinoptilolite is one of the zeolites that has been widely studied in veterinary and human medicine.
T343 68793-68979 Sentence denotes The increased usage of clinoptilolite-based products in vivo has stimulated several investigations on its safety and its positive medical effects related to human health (see [131,132]).
T344 68980-69117 Sentence denotes Finally, soluble and catalytically inactive forms of ACE2 have been shown to be potent inhibitors of SARS-CoV infection products [19,21].
T345 69118-69218 Sentence denotes An approach that could be pursued (in combination with other therapies) to inhibit SARS-CoV-2 entry.
T346 69219-69435 Sentence denotes Indeed, soluble forms of ACE2 are expected to protect from viral infection and a similar strategy using a recombinant form of human ACE2 has been proposed not only in COVID-19, but also in ARDS and PAH [108,133,134].
T347 69436-69566 Sentence denotes However, it is possible that catalytic active form of ACE2 might favour adverse effects in these specific pathological conditions.
T348 69567-69877 Sentence denotes To this regard, a clinical trial using recombinant hACE2 protein has been recently started (ClinicalTrials.gov number, NCT04287686) in COVID-19 patients and pilot clinical trials of rhACE2 in ARDS and PAH started in 2017 and 2018, respectively [108,134]; unfortunately, no conclusive results are available yet.
T349 69879-69881 Sentence denotes 6.
T350 69882-69995 Sentence denotes Correlation of Pre-existing Circulating ACE2 Activity and Increased Potential to Develop Severe Forms of COVID-19
T351 69996-70139 Sentence denotes Severe symptoms of COVID-19 have been described to correlate with pre-existing hypertension, diabetes, age and male gender [1,2,3,4,5,6,7,8,9].
T352 70140-70517 Sentence denotes It is not still clear whether it depends on constitutive hypertensive conditions and/or on anti-hypertensive treatments or on other age-related conditions, considering that the prevalence of hypertension in Chinese adults is ~ 23% and that only about 41% take prescribed antihypertensive medications, being calcium channel blockers the most commonly used (~ 50%) in China [11].
T353 70518-70756 Sentence denotes To this regard, there is an interesting report describing sACE2 activity in plasma samples of Spanish healthy subjects and patients, in which a total of 2572 subjects from a multicenter study (NEFRONA project, 2009–2011) was studied [96].
T354 70757-70875 Sentence denotes The report shows that male and advanced age were identified as independent predictors of enhanced sACE2 activity [96].
T355 70876-71067 Sentence denotes Furthermore, subjects with hypertension, diabetes, dyslipidemia, or plaques also had significantly increased circulating ACE2 activity when compared with those without these pathologies [96].
T356 71068-71283 Sentence denotes Notably, hypertensive (the most frequent comorbidity with COVID-19) and diabetic patients are often treated with ACE inhibitors (ACEIs) and/or with ARBs, suggesting a possible positive correlation [135,136,137,138].
T357 71284-71569 Sentence denotes Interestingly, circulating ACE2 activity is significantly increased in subjects on therapy with ARBs or taking oral antidiabetic agents as compared with non-treated patients, while treatment with ACEIs and cholecalciferol had no significant influence on circulating ACE2 activity [96].
T358 71570-71725 Sentence denotes In line with this observations, losartan (an ARB), but not lisinopril (an ACEI), was able to upregulate ACE2 activity in left ventricle of Lewis rats [75].
T359 71726-72035 Sentence denotes Nevertheless, plasma concentration of Ang (1–7) was significantly increased with both treatments when compared to vehicle-treated rats and it was significantly higher in ACEI-treated than ARB-treated rats [75], suggesting that ACE inhibition is able to induce an activation of the ACE2/Ang (1–7)/MasR pathway.
T360 72036-72207 Sentence denotes Although more evidence is needed in humans, the above observations suggest that ARBs should be precautionarily avoided to reduce possible ACE2-mediated viral consequences.
T361 72208-72381 Sentence denotes Indeed, under hypoxic conditions, either an ACEI or an ARB have been shown to upregulate membrane ACE2 protein expression on human pulmonary artery smooth muscle cells [58].
T362 72382-72533 Sentence denotes ACEI and ARB have been shown to work by reducing the concentration of Ang II and by inhibiting its AT1-mediated ACE2 downregulation, respectively [58].
T363 72534-72789 Sentence denotes ACEIs and ARBs might therefore play a role in the upregulation of membrane ACE2 expression under hypoxic conditions such as COVID-19, knowing that the increase of membrane bound ACE2 (before its shedding) will also increase the probability of viral entry.
T364 72790-72892 Sentence denotes Of note, ACEI and ARB antihypertensive medications are more commonly used in Europe/USA than in China.
T365 72893-73117 Sentence denotes Nevertheless, recent reports show that the use of ACEI/ARB medications in patients with COVID-19 is safe and ACEI/ARB exposure was not associated with a higher risk of having severe forms of COVID-19 [6,139,140,141,142,143].
T366 73118-73360 Sentence denotes Moreover, some reports show that ACEI/ARB treated patients may even be protected from COVID-19 and ACEI/ARB exposure was associated with a lower risk of mortality compared to those on non-ACEI/ARB antihypertensive drugs [144,145,146,147,148].
T367 73361-73561 Sentence denotes Among these reports, one indicates that the risk of severe symptoms of COVID-19 was significantly decreased in patients who took ARB drugs (but not ACEIs) compared to patients who took no drugs [144].
T368 73562-73788 Sentence denotes Differently, another report suggests that the use of ACEIs (but not ARBs) reduced risk of death and/or critical disease [146], suggesting that some of these reports did not adjust for confounders and further analyses are need.
T369 73789-73987 Sentence denotes Nevertheless, clinical trials of losartan as a treatment for COVID-19, are actually underway among patients who have not previously been treated with ARBs and/or ACEIs (NCT04312009 and NCT04311177).
T370 73988-74237 Sentence denotes However, most of hypertensive/diabetic patients are ACEI- or ARB-“pretreated”, nevertheless they have an increased risk to develop SARS, therefore ACEIs and ARBs, if not detrimental, are not expected to face the disease in non-hypertensive patients.
T371 74238-74569 Sentence denotes A possible beneficial effect of ACEIs in COVID-19 patients could indirectly come by reducing ACE2 substrate, Ang II, and finally limiting Ang (1–7) [but not Ang (1–9)] production and its (detrimental) effects; however, this is only a hypothetical possibility since, in this case, the ACE2/ACE pathway might be even more unbalanced.
T372 74570-74762 Sentence denotes To complete the picture, smokers and subjects on therapy with insulin tend to have an increased (although not significantly) circulating ACE2 activity when compared with control subjects [96].
T373 74763-75024 Sentence denotes On the other hand, increased ACE2 protein expression was reported in plasma and/or urine of physically active men after acute aerobic training or in renal cortices of spontaneous hypertensive, but not normotensive, rats after chronic aerobic training [149,150].
T374 75025-75254 Sentence denotes In addition, recent works reveal that asthma and other allergic diseases, which protect from developing COVID-19, were associated with significant reductions in levels of both zinc in plasma and ACE2 mRNA in airway cells [98,99].
T375 75255-75513 Sentence denotes On the other hand, as already mentioned, some patients with cardiovascular diseases (and inflammatory bowel disease) have an increased circulating ACE2 [22,49,151,152], which might explain the higher probability of elderly heart patients to develop COVID-19.
T376 75514-75743 Sentence denotes Interestingly, in a report on atrial fibrillation, increased plasma ACE2 activity was significantly associated not only with cardiac dysfunction, increasing age, male gender and hypertension, but also with vascular disease [152].
T377 75744-75985 Sentence denotes Altogether the data suggest a strong correlation between circulating ACE2 activity and the predisposition to develop the most severe symptoms of COVID-19, suggesting that circulating sACE2 might be a predictive biomarker of SARS development.
T378 75986-76221 Sentence denotes The surprising aspect is that circulating (differently from membrane bound) ACE2 is expected to protect from viral infection and clinical trials using recombinant ACE2 protein are being pursued (ClinicalTrials.gov number, NCT04287686).
T379 76222-76425 Sentence denotes However, even if it might not be detrimental, recombinant ACE2 is not expected to protect from COVID-19, as circulating ACE2 upregulation correlates with the most common comorbidities in severe COVID-19.
T380 76426-76722 Sentence denotes The correlation is extremely impressive and striking if we also consider the low prevalence of chronic renal disease in COVID-19 hospitalized patients (0–3%) [1,2,3,4,5,6,7,8,9] (prevalence of the disease in China ~11% [12]) which might be protected by a higher sACE2 and/or Zn2+ renal excretion.
T381 76723-76941 Sentence denotes Indeed, in chronic kidney disease patients without a history of cardiovascular disease, there was a significant decrease in circulating ACE2 activity and zinc levels when compared with healthy control subjects [96,97].
T382 76942-77251 Sentence denotes Since proteinuria was associated with lower blood levels of sACE2 protein [153] and chronic kidney disease patients had higher urinary zinc excretion than healthy controls [97], low sACE2 activity in chronic renal diseases and protection from SARS might derive from a higher sACE2 and/or Zn2+ renal excretion.
T383 77252-77498 Sentence denotes Indeed, sACE2 is detectable in urine of healthy subjects and urinary sACE2 protein levels are elevated in patients with chronic renal diseases and in hypertensive patients treated with the Ang II type 1 receptor blocker (ARB) olmesartan [41,154].
T384 77499-77724 Sentence denotes It can, therefore, be supposed that a basal hyperactivity of ACE2 and consequent ACE/ACE2 pathway disequilibrium in blood might predispose to the development of more severe COVID-19 symptoms that involve both arms of the RAS.
T385 77725-78101 Sentence denotes In this regard, different organism predisposition to infections including SARS-CoV-2 or to pathologies associated with an increased risk to develop severe forms of SARS-CoV-2 infection might depend not only on genetic ACE2 polymorphisms and organ-specific ACE2 gene/protein expression [138,155,156,157,158,159,160,161,162,163] but also on anatomical and environmental factors.
T386 78102-78278 Sentence denotes For example, ACE2 gene variants have been associated with risk for hypertension, dyslipidemia, type 2 diabetes and cardiovascular dysfunction [138,155,156,157,158,159,160,161].
T387 78279-78523 Sentence denotes Most of these variants are intronic and located in splice-site junctions or in enhancer regions while the others are placed in the 3’ UTR promoter region, suggesting their involvement in the structure/function and expression of ACE2 gene [138].
T388 78524-78676 Sentence denotes On the other hand, COVID-19 has similar risk factors of obstructive sleep apnea (OSA), suggesting a possible association between OSA and COVID-19 [164].
T389 78677-78843 Sentence denotes Indeed, high prevalence of pre-existing OSA in COVID-19 patients has been reported [165,166], indicating that OSA could be a risk factor for severe forms of Covid-19.
T390 78844-79070 Sentence denotes OSA is characterised by repetitive airway collapse with apnea/hypopnea and intermittent hypoxaemia during sleep and it is associated with hypertension, cardiovascular disease, diabetes, obesity and systemic inflammation [167].
T391 79071-79327 Sentence denotes Most of these diseases are known to predispose to increased levels of circulating ACE2 and, as already mentioned, hypoxia has been shown to upregulate both arms of the RAS; therefore, OSA might predispose to the deleterious effects of SARS-CoV-2 infection.
T392 79328-79568 Sentence denotes In OSA patients, upper airway collapsibility under passive conditions (critical closing pressure) is higher in males than in females due to anatomical factors, i.e., longer upper airways, as upper airway length correlates with OSA severity.
T393 79569-79809 Sentence denotes Indeed, upper airways in females are less collapsible and more stable during sleep than in males [167], suggesting that an anatomical factor might contribute to and result in different gender susceptibility to COVID-19 and disease severity.
T394 79810-79991 Sentence denotes Moreover, diet (e.g., zinc assumption), physical exercise and external temperature and UV radiation are all “environmental” aspects that can seasonally influence the RAS activities.
T395 79992-80105 Sentence denotes Seasonal differences of the RAS activities leading, for example, to differences in blood pressure are well known.
T396 80106-80228 Sentence denotes Of interest, the majority of coronaviruses cause cold-like illnesses and have a relatively low mutational frequency [168].
T397 80229-80302 Sentence denotes Similarly SARS-CoV-2 seems to mutate much slower than seasonal flu [169].
T398 80303-80537 Sentence denotes Nevertheless, like influenza virus, they are responsible for seasonal episodes of common cold in humans worldwide [168], suggesting that coronaviruses may possess an ability to evade immune control that is different from seasonal flu.
T399 80538-80630 Sentence denotes For example, they might favour a relatively short-term activation/memory of immune response.
T400 80631-80767 Sentence denotes Indeed, as for SARS-CoV and MERS-CoV, a short duration of immunity after SARS-CoV-2 infection has been recently suggested [170,171,172].
T401 80768-80948 Sentence denotes Seasonal cold is an annually recurring time period characterized by the prevalence of outbreaks of cold and the season occurs during the cold period of the year in each hemisphere.
T402 80949-81319 Sentence denotes Altogether these observations suggest that seasonal predisposition to some virus infections (including SARS-CoV-2) might not depend only on environmental features that directly inactivate the viruses “unprotected” outside the host (e.g., higher ultraviolet rays and temperatures), but also on seasonal indirect effects produced in the organisms by environmental changes.
T403 81321-81323 Sentence denotes 7.
T404 81324-81433 Sentence denotes Monitoring ACE/ACE2 Activity in COVID-19 in Order to Determine a Rationale Use of the Specific RAS Inhibitors
T405 81434-81541 Sentence denotes There is currently no specific pharmacotherapy to combat SARS-CoV-2 infection and its pathological effects.
T406 81542-81937 Sentence denotes Actually, the use of plasma from convalescent COVID-19 patients or of SARS-CoV-2-specific neutralizing antibodies has been shown to be a promising option for the treatment of critically COVID-19 patients [32,33,34,35,36,37,172,173]; however, it has some limitations that might be overcome by vaccine strategies or by the production of specific anti SARS-Co-V-2 therapeutic monoclonal antibodies.
T407 81938-82114 Sentence denotes Despite the promising data that demonstrate vaccine protection against SARS-CoV-2 in nonhuman primates [174], we cannot be sure to get a vaccine against SARS-CoV-2 (see [175]).
T408 82115-82365 Sentence denotes Indeed, animals immunized with inactivated SARS-CoV vaccines developed a severe (asthma-like) lung eosinophilic immunopathology when challenged with SARS-CoV, further indicating a central role of eosinophil “balanced numbers” in this pathology [176].
T409 82366-82549 Sentence denotes Vaccines might generate antibodies against viral ligand/ACE2 complex that finally blocks ACE2 activity during SARS-CoV infection and consequent downstream asthma-like events/symptoms.
T410 82550-82861 Sentence denotes On the other hand, fatal outcomes in SARS-CoV infection correlated with a cytokine storm involving elevated Th2 serum cytokines (including IL-4, IL-5 and IL-10), suggesting that an increase of Th2 cytokines possibly mediated by virus-specific CD4 T cells might be crucial in the severe forms of infection [110].
T411 82862-83276 Sentence denotes In addition to cytokine profile (such as IL-10), eosinopaenia, tachycardia, normo/hypotension (although COVID-19 and hypoxia increase Ang II and many patients are “hypertensive” and/or receiving anti-hypertensive medications) and hypoxia in SARS-CoV-2 patients are compatible with downstream events stemming from both an excessive ACE2 pathway upregulation and activation of positive feedback loops (see Figure 2).
T412 83277-83473 Sentence denotes ACE2 and (anti-inflammatory) IL-10 hyperproduction may ultimately trigger subsequent compensatory (and deleterious) responses, leading to both renin/ACE and pro-inflammatory cytokine upregulation.
T413 83474-83593 Sentence denotes In line with this hypothesis, a longitudinal study showed that IL-6 increases late during the COVID-19 progression [3].
T414 83594-83890 Sentence denotes Altogether these data imply not only that the ACE2 is the “vehicle” of viral entry into the host cells, but also that virus-dependent and virus-independent mechanisms may sustain activation of both arms of the RAS and of the inflammatory system, finally promoting SARS-induced multi-organ injury.
T415 83891-84201 Sentence denotes Unfortunately, complete analysis of circulating levels of ACE/ACE2 proteins and activities, together with ACE and ACE2 substrates and products i.e., Ang I, Ang 1–9, Ang II, Ang (1–7) and Ang (1–5), des-Arg(9)-bradykinin and the inactive metabolite bradykinin (1–7) is lacking to address the current hypothesis.
T416 84202-84385 Sentence denotes The required data could be obtained from blood sample analyses, however, it is important to consider that:(1) Organ-specific local microenvironment might not reflect the systemic one;
T417 84386-84622 Sentence denotes (2) S1-sACE2 and SARS-CoV-2-sACE2 complexes, formed by viral-induced ACE2 shedding or by subsequent binding of sACE2 with viral particles or S1 fragments in the circulation, might not be detectable by some anti-ACE2 antibodies in ELISA.
T418 84623-84846 Sentence denotes Therefore, since the complexes might prevent/mask sACE2 antibody recognition but not the enzymatic activity, sACE2 detection (and its real concentration) by ELISA in blood samples of COVID-19 patients might not be reliable;
T419 84847-85143 Sentence denotes (3) In order to evaluate circulating ACE/ACE2 activity, we can determine it by adding fluorogenic (RAS) substrates to plasma samples without (thus considering also the endogenous ACE2 inhibitor present in plasma [116]) or with adding ZnCl2, which is able to induce ACE/ACE2 maximal activity [96];
T420 85144-85295 Sentence denotes (4) circulating concentrations ACE/ACE2 substrates/products likely depend on the:(a) level of ACE/ACE2 pathway activity and availability of substrates;
T421 85296-85429 Sentence denotes (b) level of expression of the respective receptors (AT1R, AT2R and MasR) that bind and remove ligand products away from circulation.
T422 85430-85652 Sentence denotes For example, Ang (1–7) concentration in blood by ACE2 pathway upregulation is dependent both on the increase of the (antagonistic) Ang II (and its precursor, Ang I) and on MasR expression on surface of cells in the organs.
T423 85653-85894 Sentence denotes To this regard, the detection of inactive metabolites, such as bradykinin (1–7), in COVID-19 patients and comparison with its concentration in healthy subjects could be the most indicative and reliable markers of ACE2 activity in the plasma.
T424 85895-86298 Sentence denotes Of interest, a report that described the ex vivo effect of human rACE2 on the levels of several endogenous Ang peptides in plasma samples, thus mimicking an acute increase of systemic ACE2 activity in plasma [115] showed a strong reduction of Ang II (as expected), a moderate reduction of Ang I and a significant (more than five-fold) increase of Ang (1–9), Ang (1–7) and (ACE-produced) Ang (1–5) [115].
T425 86299-86421 Sentence denotes Therefore, Ang (1–5) may also be an interesting surrogate marker of ACE-ACE2 combined activity in COVID-19 patients [115].
T426 86422-86942 Sentence denotes At the present time, it has been reported that plasma levels of Ang II in SARS-CoV-2 infected patients are markedly elevated as compared with healthy subjects (interquartile range between 260–360 pg/mL and 65–120 pg/mL, respectively) and linearly associated to viral load and lung injury [177]; unfortunately, nobody has tested the levels of Ang (1–7), Ang (1–9), Ang (1–5) and bradykinin (1–7), some of which might be at high levels as well, thus justifying both normo/hypotension and eosinopaenia in COVID-19 patients.
T427 86943-87126 Sentence denotes More information on the RAS peptides in plasma of Acute Respiratory distress syndrome, a COVID-19-like disease, (and pulmonary arterial hypertension) is instead available (see Box 6).
T428 87127-87210 Sentence denotes Box 6 Acute Respiratory distress syndrome and hyperactivation of the RAS pathways.
T429 87211-87337 Sentence denotes The main clinical feature of ARDS patients is the progressive deterioration of lung function leading to progressive hypoxemia.
T430 87338-87524 Sentence denotes ARDS can be induced by different causes such as ZnCl2 aspiration, sepsis, trauma, acute pancreatitis, or pneumonias following virus infections such as SARS-CoVs or human influenza virus.
T431 87525-87661 Sentence denotes ACE insertion/deletion polymorphisms correlated with severity of ARDS in humans, suggesting that the RAS could have a role in ARDS [44].
T432 87662-87840 Sentence denotes In animal models, ACE2 protected from acute lung by inhibiting Ang II/AT1R activity [15], for this reason the use of recombinant ACE2 in ARDS has been proposed and pursued [134].
T433 87841-88171 Sentence denotes Clinical trials with recombinant human ACE2 started in healthy volunteers in 2009 (ClinicalTrials.gov number, NCT00886353 [178]), then it was tested in ARDS (ClinicalTrials.gov number, NCT01597635 [134]), PAH (ClinicalTrials.gov number, NCT01884051 [108]) and finally in COVID-19 patients (ClinicalTrials.gov number, NCT04287686).
T434 88172-88270 Sentence denotes Despite its safe use, no conclusive evidence in support of its use in these diseases was reported.
T435 88271-88587 Sentence denotes Of interest, in the plasma samples from ARDS patients, levels of Ang I have been shown to be significantly increased in non-survivors (interquartile range 1990–16950 pg/mL) compared to survivors (interquartile range 730–5660 pg/mL) [92], suggesting a marked increase of renin activity in non-surviving ARDS patients.
T436 88588-89042 Sentence denotes Unfortunately, no comparisons of the two ARDS groups with healthy subjects (interquartile range 35–66 pg/mL, markedly lower than both patient groups [179]) were reported; this is important to consider since the plasma concentrations of the RAS peptides may significantly differ depending on method of detection (ELISA versus vs. mass spectrometry) and, in particular, on protocol of determination (endogenous versus equilibrium Ang peptide levels [179]).
T437 89043-89176 Sentence denotes Endogenous RAS peptide concentrations can be evaluated collecting and stabilizing blood samples with a RAS enzyme inhibitor cocktail.
T438 89177-89389 Sentence denotes Differently, heparinized plasma samples can be incubated at 37 °C to induce ex vivo equilibrium, which unveils the presence of renin, ACE and/or ACE2 activity in the plasma (equilibrium Ang peptide levels) [179].
T439 89390-89477 Sentence denotes This last protocol usually gives significantly higher levels of the RAS peptides [179].
T440 89478-90005 Sentence denotes For example, in healthy subjects, the normal ranges (interquartile ranges) of endogenous RAS peptides, Ang I, Ang II, Ang (1–7), Ang (1–9) and Ang (1–5) were 12–24 pg/mL, 1–12 pg/mL, <2 pg/mL, <4 pg/mL and < 1 pg/mL, respectively, differently the normal range after ex vivo equilibrium of the same peptides were 35–66 pg/mL, 110–200 pg/mL, < 2 pg/mL, < 4 pg/mL and < 1 pg/mL, respectively [179], indicating the presence of renin and ACE (but no ACE2) activity (as highlighted by Ang peptide increases upon ex vivo equilibrium).
T441 90006-90208 Sentence denotes Similarly, another report that evaluated Ang II and Ang (1–7) in healthy males showed normal endogenous ranges ~ 14.5 pg/mL and 0.9 pg/mL, respectively, and an Ang (1–7)/Ang II ratio ~ 0.06 ratio [180].
T442 90209-90471 Sentence denotes Moreover, Ang (1–7), Ang I, Ang (1–9) and Ang (1–7)/Ang II ratio were significantly higher in ACEI-treated hypertensive patients compared to healthy subjects [180], suggesting that inhibition of ACE predisposes to upregulation of the ACE2/Ang (1–7)/MasR pathway.
T443 90472-90693 Sentence denotes Notably, two different reports that evaluated the RAS peptides in ARDS patients using the similar method of detection (high performance liquid chromatography plus mass spectrometry) showed significantly different results.
T444 90694-90826 Sentence denotes One report showed that Ang II ranged (interquartile range) between 120–630 pg/mL (non-survivors) and 70–2220 pg/mL (survivors) [92].
T445 90827-91111 Sentence denotes A second report showed significantly lower values of Ang II, (interquartile range) between 40–150 ng/mL (non-survivors with placebo) and 5–20 pg/mL (survivors with placebo) (see Supplementary Data [134]), suggesting that they used different protocols of the RAS peptide determination.
T446 91112-91265 Sentence denotes Nevertheless, both Ang (1–7) and Ang (1–7)/Ang II ratios found in ARDS patients of both reports [92,134] were significantly higher than healthy subjects.
T447 91266-91458 Sentence denotes One report showed that Ang (1–7) ranged (interquartile range) between 2.5–10 pg/mL (see Figure 2B of [134]), Ang II between 5–20 pg/mL (see Figure 2 of [134]) and Ang (1–7)/Ang II ratio ~ 0.5.
T448 91459-91627 Sentence denotes Moreover, in the report in which the elevated concentrations of Ang I and Ang II indicate an ex vivo equilibrium of the RAS peptides, the increase was even more marked.
T449 91628-91946 Sentence denotes In that report, Ang (1–7) (< 1pg/mL in healthy subjects) ranged between 80–1070 pg/mL and Ang (1–7)/Ang II ratio (~ 0.06 in healthy subjects) ranged between 0.24–1.82 [92], suggesting that ACE2 activity (and ACE2 presence in plasma samples) was significantly increased in ARDS patients as compared to healthy subjects.
T450 91947-92128 Sentence denotes In line with this hypothesis, there was the determination of Ang (1–9), whose production from Ang I exclusively depends on ACE2 (which also compete with ACE for the same substrate).
T451 92129-92530 Sentence denotes In normal healthy subjects, it was reproducibly below the limit of quantification [179,180], differently, both in ex vivo treatments of plasma samples with human rACE2 [115,181] and in ARDS patients, it was markedly increased (Ang (1–9) ranged between 100–3080 pg/mL) [92], suggesting both that the dominating activity of ACE in plasma of healthy subjects is overcome by that of ACE2 in ARDS patients.
T452 92531-92608 Sentence denotes Therefore, Ang (1–9) may represent a good surrogate marker for ACE2 activity.
T453 92609-92817 Sentence denotes Similarly to Ang (1–9), there was the determination of Ang (1–5), whose production depend on both ACE2 [that produces Ang (1–7) from Ang II] and ACE [that produces Ang II from I and Ang (1–5) from Ang (1–7)].
T454 92818-93083 Sentence denotes Ang (1–5) was undetectable in healthy subjects [178,179]; however, it was significantly increased in ARDS patients (interquartile range between 50–730 pg/mL [92]), suggesting that both ACE2 and ACE activity were likely upregulated as compared with healthy subjects.
T455 93084-93207 Sentence denotes The activation for both arms of the RAS needs of the contemporary activation renin, the rate-determining enzyme of the RAS.
T456 93208-93538 Sentence denotes Indeed, analysis of plasma samples (from a healthy subjects), treated ex vivo with recombinant renin, showed an increase of Ang I, Ang II, Ang (1–7) and Ang (1–5), but not Ang (1–9) [115,179,181], further suggesting both the ACE2 specific activity in producing Ang (1–9) and an activation of both arms of the RAS in ARDS patients.
T457 93539-93840 Sentence denotes Finally, in vivo or ex vivo administration of human rACE2 in plasma samples produced an increase not only of Ang (1–9) but also of Ang (1–5) and Ang (1–7) in both healthy subjects [178] and ARDS patients [134], indicating that all three Ang peptides might represent surrogate markers of ACE2 activity.
T458 93841-94142 Sentence denotes Of interest, the mean arterial pressure of ARDS patients was markedly low and significantly lower in non–survivors (mean value 65 mmHg and more likely need vasopressor support) compared to survivors (mean value 71 mmHg) [92], which may likely be a consequence of the above described ACE2 upregulation.
T459 94143-94230 Sentence denotes Interestingly, similar features were also detected in PAH and coronary atherosclerosis.
T460 94231-94459 Sentence denotes In particular, a significant increase of both Ang II and Ang (1–7) peptides was observed in plasma of these patients [108,182] and plasma levels of TNF-α were significantly elevated in the critical coronary artery disease [182].
T461 94460-94679 Sentence denotes Moreover, despite a significant increase of Ang II/Ang (1–7) ratio (that suggested a therapeutic use of recombinant hACE2 in PAH patients) systolic and diastolic blood pressures were in the range of normality [108,182].
T462 94680-94890 Sentence denotes Altogether these observations suggest that Ang peptide ratios are not reliable markers for disease status in these pathologies; rather, increased plasma amounts of each RAS peptide should be careful considered.
T463 94892-94894 Sentence denotes 8.
T464 94895-94948 Sentence denotes Hypothesizing Pharmacological Treatments for COVID-19
T465 94949-95059 Sentence denotes Based on the above described hypothesis, inhibition of ACE2 pathway might be beneficial for COVID-19 patients.
T466 95060-95320 Sentence denotes Indeed, the clinical picture as a whole is consistent with an ACE2 gain of function (possibly due to both circulating active forms of S1-sACE2 complexes and local forms of SARS-CoV-2-sACE2 complexes) rather than an ACE2 loss of function, as initially supposed.
T467 95321-95515 Sentence denotes Therefore, inhibition of ACE2/Ang (1–7)/MasR axis or other ACE2 pathways to restore ACE/ACE2 balance might be needed, at least in the first phases of the disease when hypoxia is not yet induced.
T468 95516-95657 Sentence denotes Different strategies could be pursued through ACE2 pathway inhibitors and/or MasR antagonists and/or renin inhibitors and/or metal chelators.
T469 95658-95863 Sentence denotes Several different molecules have been designed to specifically inhibit human ACE2 enzyme (both membrane bound and soluble forms) or human MasR signal transduction, but only a few have been studied in vivo.
T470 95864-96010 Sentence denotes Some ACE2 pathway inhibitors have been widely used in mouse/rat models, as control of human and mouse ACE2 activity or in mouse models of colitis.
T471 96011-96303 Sentence denotes Thanks to mouse/rat in vivo experiments and clinical trial results in human participants it has been possible to infer toxicity/efficacy for some human ACE2 inhibitory molecules (MLN-4760/C16/GL1001/ORE1001, Dx600 and A779) that may be exploited to face this exceptionally dramatic situation.
T472 96304-96554 Sentence denotes Unfortunately, to my knowledge, only one (MLN-4760/C16/GL1001/ORE1001) of the ACE2-specific inhibitors has been tested in vivo in humans in a Phase I clinical trial long time ago (http://oreholdings.com/wp-content/uploads/2013/06/09.02.09-S-4-A.pdf).
T473 96555-96669 Sentence denotes Here, I have focused my attention on inhibitors of human ACE2 pathway that were consistently administered in vivo.
T474 96670-97046 Sentence denotes Making use of published reports in which human/rodent ACE2 pathway inhibitors were administered in vivo, I have hypothesized a possible therapeutic pharmacological intervention through an inhibition strategy of the RAS pathways for COVID-19 in patients experiencing both mild and critical, advanced and untreatable stages of the disease (the most problematic cases to manage).
T475 97048-97052 Sentence denotes 8.1.
T476 97053-97081 Sentence denotes Inhibition of ACE2: MLN-4760
T477 97082-97753 Sentence denotes Briefly, one of the best candidates to treat COVID-19 patients, but not to prevent viral entry, is the small synthetic molecule MLN-4760 (specific ACE2 inhibitor, also known as C16, GL1001 or ORE1001, [113]) for the following reasons:(1) It has been shown to bind/inhibit ACE2 enzymatic activity even at low/acidic pH (pH 6.5, [115]) typical of hypercapnia (as it might occur in lungs of COVID-19 patients) when human ACE2 activity is maximal [79]; nevertheless, it retains its inhibitory effects on soluble ACE2 bound to spike proteins [24], indicating that it is able to bind and inhibit ACE2 activity regardless ACE2 binding to SARS-CoV-2 particles or to S1 fragments.
T478 97754-98158 Sentence denotes (2) No significant adverse effects were described upon its chronic administration neither alone nor in combination with ACE2 activators (while inhibiting their activating effects) nor after inducing functional impairment of ACE2 activity in rodent experiments in vivo [52,117,118,122,183,184] nor in a clinical Phase I trial in humans (http://oreholdings.com/wp-content/uploads/2013/06/09.10.09-425.pdf);
T479 98159-98241 Sentence denotes (3) Its administration by different route is well described in rodents and humans.
T480 98242-98592 Sentence denotes In particular:(a) Chronic administration (about 4 weeks) of C-16/DLM-4760 in combination with ACE2 activating treatments was performed by daily intraperitoneal injection at a dose of 25mg/kg in distilled water (as a solution of 42 mg/mL) or 0.9% sterile saline (as a solution of 84 mg/mL using a 0.5-mL insulin syringe) freshly prepared [52,183,184].
T481 98593-98924 Sentence denotes (b) Alternatively, chronic administration (about 8 days) of GL1001/DLM-4760 disodium salt in combination with an ACE2 activating treatment was performed by subcutaneous injection (5mL/kg) containing up to a dose of 300 mg/kg, twice a day, formulated in a vehicle solution [15% 2-hydroxypropyl-β-cyclodextrin (HPBDC)/85% H2O] [122].
T482 98925-99010 Sentence denotes Subchronic doses of GL1001 indicate no adverse effects up to 1,000 mg/kg (see [122]).
T483 99011-99100 Sentence denotes (c) In humans ORE1001/GL1001/MLN-4760 was already proposed and tested in clinical trials.
T484 99101-99269 Sentence denotes Its pharmaceutical indication was for digestive tract inflammations (Inflammatory bowel disease, gastritis and colitis) that are correlated with overexpression of ACE2.
T485 99270-99346 Sentence denotes In a Phase I clinical testing up 14 days dosing, ORE1001 was well tolerated.
T486 99347-99431 Sentence denotes Subjects received drug (dosing up to 2100 mg) with no side adverse effects reported.
T487 99432-99569 Sentence denotes In particular, 47 subjects received single-dose from 2.1 to 2100 mg and 24 subjects received 14 day multiple doses from 50 mg to 1800 mg.
T488 99570-99659 Sentence denotes All doses were well tolerated, with no significant side effects including blood pressure.
T489 99660-99817 Sentence denotes Pharmacokinetics of orally administered capsules was consistent with once-daily dosing. (http://oreholdings.com/wp-content/uploads/2013/06/09.10.09-425.pdf).
T490 99818-99976 Sentence denotes 300 mg (active drug) oral capsules were used in a Phase Ib/IIa clinical trial that was, however, abandoned. (https://clinicaltrials.gov/ct2/show/NCT01039597).
T491 99977-100126 Sentence denotes (d) Finally, MLN-4760 was also administered (2.5 mg/kg per day) by nasal inhalation for 2–3 days in lung-infected mice by Pseudomonas bacteria [185].
T492 100127-100268 Sentence denotes Interestingly, the report underscores the role played by local concentration of molecules (ACE2) in modulating lung inflammation and disease.
T493 100269-100502 Sentence denotes For these reasons, in diseases involving respiratory tract, like SARS, inhalation treatment is preferable, even for the lower concentration (and hopefully lower toxicity) of MLN-4760 needed for this route of treatment administration.
T494 100503-100618 Sentence denotes Different routes of MLN-4760 treatment administration can be pursued depending on the hospital condition/expertise.
T495 100619-100781 Sentence denotes In this exceptionally critical situation, it could be delivered to critical untreatable patients as a controlled “compassionate use”, in particular by inhalation.
T496 100782-100981 Sentence denotes However, when, under hypoxic conditions, both arms of the RAS are upregulated, it might have a limited action and, by shifting the balance of ACE/ACE2 ratio in favour of ACE, might be even dangerous.
T497 100982-101193 Sentence denotes Instead, specific inhibition of ACE2 enzymatic activity might effectively work in preventing the establishment of positive feedback loops in COVID-19 patients who are suffering from mild symptoms of the disease.
T498 101194-101357 Sentence denotes MLN-4760 is sold by different companies, that, in case it works, could be encouraged to manufacture the molecule, actively contributing to face this global threat.
T499 101358-101505 Sentence denotes On the other hand, the drug could be also synthesized in University chemistry labs because, to my knowledge, is no longer under patent restriction.
T500 101506-101937 Sentence denotes MLN-4760, whose clinical development was abandoned after phase I trials (clinical name, ORE1001), is actually an interesting compound that could be useful for all patients in which a specific ACE2 upregulation is proven and associated to different (heart/lung/liver/intestine/kidney/immune system/blood/coagulation, etc.) pathological conditions related to ACE2 pathway downstream events, as it seems to occur in COVID-19 patients.
T501 101938-102334 Sentence denotes Although in blood of normal subjects sACE2 activity is undetectable because its catalytic activity in human plasma is masked by an endogenous inhibitor [116] and chronic ACE2 activation may be deleterious, some patients might need of sACE2 activity to better face an acute pathological condition, therefore a careful monitoring of clinical parameters should be performed during patient treatment.
T502 102336-102340 Sentence denotes 8.2.
T503 102341-102370 Sentence denotes Inhibition of Renin Activity:
T504 102371-102380 Sentence denotes Aliskiren
T505 102381-102488 Sentence denotes An alternative approach is to inhibit the RAS pathway at its origin by inhibiting renin enzymatic activity.
T506 102489-102702 Sentence denotes Regarding renin inhibitors, aliskiren is the sole compound in this class of drugs that was approved by the US Food and Drug Administration in March 2007 and commercialized for the management of hypertension [186].
T507 102703-102839 Sentence denotes Aliskiren may be used alone or in combination with other drugs to face COVID-19, in particular the severe forms of SARS-CoV-2 infection.
T508 102840-102945 Sentence denotes Indeed, in patients with severe symptoms of COVID-19 hypoxia might have upregulated both arms of the RAS.
T509 102946-103108 Sentence denotes Therefore, aliskiren might be a useful “tool” to reduce production of Ang I, the necessary fuel for both ACE and ACE2 hyperactivity and their detrimental effects.
T510 103109-103325 Sentence denotes Aliskiren treatment in rats has been shown to upregulate both AT1R and MasR expression probably as consequence of a compensation mechanism when both Ang II and Ang (1–7) ligands are reduced by renin inhibition [187].
T511 103326-103546 Sentence denotes Of particular interest in the context of SARS-CoV-2 infection, the treatment has been shown to reduce expression of both AT2R and ACE2, thus possibly performing a multiple action in inhibiting both arms of the RAS [187].
T512 103547-103663 Sentence denotes Similarly, cation chelating agents such as CaNa2EDTA or nicotianamine might also work, although at different levels.
T513 103665-103669 Sentence denotes 8.3.
T514 103670-103687 Sentence denotes Chelating Agents:
T515 103688-103697 Sentence denotes CaNa2EDTA
T516 103698-103976 Sentence denotes As already mentioned, chelating agents, by limiting zinc cellular availability, might influence hyperactivity, synthesis and conformation of both ACE2 and ACE, which may impair not only ACE2 (and ACE) enzymatic activity but also its availability on cell surface for viral entry.
T517 103977-104159 Sentence denotes For these reasons, chelating agents might be effective to counter SARS-CoV-2 infection, and in particular when (e.g., induced by hypoxia) both arms of the RAS are likely upregulated.
T518 104160-104351 Sentence denotes Differently from renin inhibitors, more chelating agents are commercially available and both classes of drugs might be administered, alone or in combination with other therapies for COVID-19.
T519 104352-104642 Sentence denotes Of note, these classes of drugs might be beneficial not only for SARS-CoV-2 infection but also for other disease in which both arms of the RAS (and of the inflammatory system) are upregulated, as for example ARDS, PAH and other pathologies associated to chronic hypoxia and cardiac failure.
T520 104643-104939 Sentence denotes Indeed, both Ang-II and Ang-(1–7) upregulation and a cytokine storm are common aspects in patients not only with ARDS and PAH but also with critical coronary artery disease [182], suggesting an upregulation of both arms of the RAS and of the inflammatory system in several different dysfunctions.
T521 104940-105043 Sentence denotes Notably, a number of clinical trials have indicated the utility of CaNa2EDTA in coronary heart disease.
T522 105044-105163 Sentence denotes It was believed that chelation therapy might alter plaque morphology and volume, or improve endothelial function [123].
T523 105164-105211 Sentence denotes However, the evidence was not convincing [123].
T524 105212-105317 Sentence denotes Future clinical trials on selected patients with both ACE and ACE2 upregulation might be more convincing.
T525 105318-105447 Sentence denotes It is clear that similar pathways of activation can lead to different outcomes depending on individual predisposition/background.
T526 105448-105666 Sentence denotes Therefore, future efforts to understand the genetic, morpho-physiological, environmental and lifestyle factors that individually affect the predisposition to a specific disease with a precision medicine must be pursed.
T527 105667-105838 Sentence denotes To avoid disrupting extracellular calcium levels, CaNa2EDTA formulation is typically employed as an antidote for lead poisoning or as an extracellular zinc chelator [123].
T528 105839-105980 Sentence denotes CaNa2EDTA is poorly absorbed in the gastrointestinal tract therefore can be preferentially administered by parenteral route or by inhalation.
T529 105981-106222 Sentence denotes Nevertheless, oral tablets (e.g., 250–500 mg/tablet) or suppositories of CaNa2EDTA might also work in reducing plasma zinc levels by inhibiting intestinal zinc absorption (the only physiological way of zinc uptake by the organism) [188,189].
T530 106223-106355 Sentence denotes In this regard, eight men showing elevated lead concentrations were given a seven-day course of CaNa2EDTA, 4 g/day in divided doses.
T531 106356-106491 Sentence denotes Oral CaNa2EDTA caused a rise in lead excretion within few hours, suggesting that orally administered drug was partially absorbed [188].
T532 106492-106636 Sentence denotes Importantly, the trial in the eight lead workers demonstrated that oral administration of CaNa2EDTA was safe and produced no side-effects [188].
T533 106637-106907 Sentence denotes However, the FDA-approved method for delivery of CaNa2EDTA in treatment of lead poisoning is intravenously or intramuscularly and the recommended dose for asymptomatic adults and pediatric patients with elevated blood lead levels is 1000 g/m2/day (~0,05 g/kg/day) [190].
T534 106908-107034 Sentence denotes CaNa2EDTA was usually administered for 5–10 days followed by an interval of at least 5–10 days before a second administration.
T535 107035-107093 Sentence denotes Unfortunately, intravenous administration is very painful.
T536 107094-107377 Sentence denotes Administration of CaNa2EDTA via nebulizer has also been pursued for inhalation therapy in pulmonary metal poisonings to protect lung tissue and reduce its systemic uptaken [123]; moreover, nebulized solutions containing EDTA have been proven safe, not inducing adverse effects [191].
T537 107378-107603 Sentence denotes For the sake of completeness, the unconventional methods for administering chelating agents such as rectal or inhalatory administration are not FDA approved methods for delivery and they have not been studied in detail [192].
T538 107604-107754 Sentence denotes CaNa2EDTA diffuses mainly in the extracellular fluids, where it is not significantly metabolized, and it is excreted rapidly by glomerular filtration.
T539 107755-107853 Sentence denotes The chelator has a half-life of 1.4 to 3 h in adults and is completely excreted within 24 h [123].
T540 107854-107935 Sentence denotes For all of the above reasons, CaNa2EDTA might be employed in therapy of COVID-19.
T541 107936-108190 Sentence denotes However, before beginning any therapy with medication, particularly in the case of new diseases (such as COVID-19) or new treatments, a careful patient selection for these new treatments is essential to prevent unnecessary toxicity (“first do not harm”).
T542 108192-108196 Sentence denotes 8.4.
T543 108197-108225 Sentence denotes Safety and Efficacy Concerns
T544 108226-108610 Sentence denotes Unfortunately, diseases of different aetiologies may present similar final dysfunction/alterations (e.g., cardiac dysfunction/lung alterations/thrombosis are induced by excessive activation of either AT1R or MasR/AT2R pathways, see Figure 1), while diseases with same aetiologies may present different final dysfunction/alterations depending on patients (COVID-19 is a clear example).
T545 108611-108823 Sentence denotes This confounding aspect of diseases can lead to erroneous interpretations, and only defining the correct and early molecular origin of diseases is possible to reach a successful outcome if a therapy is available.
T546 108824-109016 Sentence denotes In order to decide who to treat, and when to start treatment, it is important to define the entity of dysfunctions, probability of treatment success and probability to develop adverse effects.
T547 109017-109130 Sentence denotes To promptly intervene in order to prevent severe forms of COVID-19, we need early markers of disease progression.
T548 109131-109527 Sentence denotes To this regard, if plasma (free) Zn2+ (or total zinc/albumin molar ratio), albumin, IL-10, Ang (1–9), Ang (1–7), Ang (1–5) and/or bradykinin (1–7) will be proven to be reliable surrogate markers for ACE and/or ACE2 enzymatic activity in vivo, they could be exploited, together with circulating ACE and ACE2 activity evaluation, in order to decide who and when to start treating COVID-19 patients.
T549 109528-109626 Sentence denotes Alternatively, eosinopaenia and hypotension may be also exploited as signs of disease progression.
T550 109627-110053 Sentence denotes In any case, since the conditions of some patients can be critical, it is highly recommended to administer the minimal effective dose in order to reduce possible side effects, starting with low and increasing doses, while at the same time monitoring patient status and early signs of disease progression (e.g., blood pressure, eosinophil counts, molecular concentrations of the RAS peptides and other markers of inflammation).
T551 110054-110454 Sentence denotes The aim of the project was not necessarily to stop viral entry (the epithelial cells take already care of it shedding ACE2) but to block positive feedback loops that follow the cellular response to SARS-CoV-2 infection, which are likely the main cause of the severe symptoms associated with COVID-19, doing so, the disease might hopefully become like a simple flu, a spontaneously eradicable disease.
T552 110455-110585 Sentence denotes At the moment, I am alone in proposing these new and non-conventional therapeutic approaches that may or may not work on COVID-19.
T553 110586-110771 Sentence denotes In doing so, I have not only described a rationale/strategy to counter COVID-19, but also provided practical information to optimize the RAS inhibitors based on known experimental data.
T554 110772-110961 Sentence denotes Before any in vivo drug administration (e.g., ACE2 inhibitor), it has to be checked the biological activity (e.g., ACE2) that is affected by the drug, considering the possible side effects.
T555 110962-111140 Sentence denotes However, this is not always the case and, in some cases, patients are treated without a careful evaluation of the biological parameter that is modulated by the administered drug.
T556 111141-111353 Sentence denotes In this regard, I have tried to address all aspects of the RAS inhibition in detail because my main concern is that the use of these approaches in a wrong way may lead to a failure or even to deleterious effects.
T557 111354-111597 Sentence denotes That is why I have meticulously described all the steps before possible administration and provided the guideline suggestions and specific recommendations in order to increase the probability of success and to minimize the deleterious effects.
T558 111598-111698 Sentence denotes The readers are, however, expected and encouraged to debate and make their own optimized guidelines.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T2 991-1011 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T3 1021-1033 Phenotype denotes coagulopathy http://purl.obolibrary.org/obo/HP_0003256
T4 1053-1061 Phenotype denotes acidosis http://purl.obolibrary.org/obo/HP_0001941
T5 1063-1070 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T6 1077-1091 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T7 1178-1190 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T8 1349-1355 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T9 1570-1576 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T10 2182-2194 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T11 2802-2824 Phenotype denotes chronic kidney disease http://purl.obolibrary.org/obo/HP_0012622
T12 2874-2880 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T13 3258-3275 Phenotype denotes acute lung injury http://www.orpha.net/ORDO/Orphanet_178320
T14 5396-5407 Phenotype denotes hypotension http://purl.obolibrary.org/obo/HP_0002615
T15 5487-5498 Phenotype denotes tachycardia http://purl.obolibrary.org/obo/HP_0001649
T16 13311-13322 Phenotype denotes hypotension http://purl.obolibrary.org/obo/HP_0002615
T17 14468-14477 Phenotype denotes cirrhosis http://purl.obolibrary.org/obo/HP_0001394
T18 14857-14884 Phenotype denotes increases in blood pressure http://purl.obolibrary.org/obo/HP_0032263
T19 15216-15238 Phenotype denotes ventricular arrhythmia http://purl.obolibrary.org/obo/HP_0004308
T20 15240-15251 Phenotype denotes heart block http://purl.obolibrary.org/obo/HP_0012722
T21 15253-15276 Phenotype denotes ventricular tachycardia http://purl.obolibrary.org/obo/HP_0004756
T22 15290-15314 Phenotype denotes ventricular fibrillation http://purl.obolibrary.org/obo/HP_0001663
T23 15583-15604 Phenotype denotes myocardial infarction http://purl.obolibrary.org/obo/HP_0001658
T24 15910-15931 Phenotype denotes myocardial infarction http://purl.obolibrary.org/obo/HP_0001658
T25 15965-15987 Phenotype denotes cardiovascular disease http://purl.obolibrary.org/obo/HP_0001626
T26 16094-16114 Phenotype denotes hypercholesterolemia http://purl.obolibrary.org/obo/HP_0003124
T27 16780-16818 Phenotype denotes disseminated intravascular coagulation http://purl.obolibrary.org/obo/HP_0005521
T28 16968-16979 Phenotype denotes proteinuria http://purl.obolibrary.org/obo/HP_0000093
T29 17193-17202 Phenotype denotes hepatitis http://purl.obolibrary.org/obo/HP_0012115
T30 17205-17214 Phenotype denotes cirrhosis http://purl.obolibrary.org/obo/HP_0001394
T31 17451-17458 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T32 17668-17675 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T33 18097-18104 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T34 18367-18374 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T35 18411-18418 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T36 18809-18816 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T37 18939-18946 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T38 18970-18981 Phenotype denotes hypercapnia http://purl.obolibrary.org/obo/HP_0012416
T39 19124-19132 Phenotype denotes acidosis http://purl.obolibrary.org/obo/HP_0001941
T40 19675-19682 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T41 19683-19694 Phenotype denotes hypercapnia http://purl.obolibrary.org/obo/HP_0012416
T42 20326-20352 Phenotype denotes inflammatory bowel disease http://purl.obolibrary.org/obo/HP_0002037
T43 20850-20868 Phenotype denotes pulmonary fibrosis http://purl.obolibrary.org/obo/HP_0002206
T44 20952-20959 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T45 20960-20971 Phenotype denotes hypercapnia http://purl.obolibrary.org/obo/HP_0012416
T46 20973-20980 Phenotype denotes Hypoxia http://purl.obolibrary.org/obo/HP_0012418
T47 21713-21729 Phenotype denotes pulmonary oedema http://purl.obolibrary.org/obo/HP_0100598
T48 22403-22409 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T49 22473-22479 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T50 22525-22531 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T51 24159-24166 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T52 25949-25956 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T53 29310-29317 Phenotype denotes Hypoxia http://purl.obolibrary.org/obo/HP_0012418
T54 29345-29356 Phenotype denotes hypercapnia http://purl.obolibrary.org/obo/HP_0012416
T55 29755-29766 Phenotype denotes Hypotension http://purl.obolibrary.org/obo/HP_0002615
T56 30503-30510 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T57 30696-30703 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T58 31582-31589 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T59 31590-31601 Phenotype denotes hypotension http://purl.obolibrary.org/obo/HP_0002615
T60 35246-35259 Phenotype denotes hyperactivity http://purl.obolibrary.org/obo/HP_0000752
T61 36473-36491 Phenotype denotes cardiac arrhythmia http://purl.obolibrary.org/obo/HP_0011675
T62 37134-37147 Phenotype denotes Hyperactivity http://purl.obolibrary.org/obo/HP_0000752
T63 38359-38370 Phenotype denotes hypotension http://purl.obolibrary.org/obo/HP_0002615
T64 39593-39613 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T65 39702-39728 Phenotype denotes inflammatory bowel disease http://purl.obolibrary.org/obo/HP_0002037
T66 40320-40336 Phenotype denotes hypoalbuminaemia http://purl.obolibrary.org/obo/HP_0003073
T67 41950-41972 Phenotype denotes chronic kidney disease http://purl.obolibrary.org/obo/HP_0012622
T68 42003-42025 Phenotype denotes cardiovascular disease http://purl.obolibrary.org/obo/HP_0001626
T69 42611-42617 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T70 42723-42729 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T71 43334-43339 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T72 43517-43526 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T73 43589-43594 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T74 43621-43626 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T75 43628-43635 Phenotype denotes fatigue http://purl.obolibrary.org/obo/HP_0012378
T76 43637-43648 Phenotype denotes muscle ache http://purl.obolibrary.org/obo/HP_0003326
T77 43650-43655 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T78 43657-43664 Phenotype denotes dyspnea http://purl.obolibrary.org/obo/HP_0002094
T79 44567-44598 Phenotype denotes pulmonary arterial hypertension http://purl.obolibrary.org/obo/HP_0002092
T80 44947-44961 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T81 48789-48812 Phenotype denotes cardiovascular diseases http://purl.obolibrary.org/obo/HP_0001626
T82 49008-49027 Phenotype denotes Alzheimer’s disease http://purl.obolibrary.org/obo/HP_0002511
T83 49171-49196 Phenotype denotes neurodegenerative disease http://purl.obolibrary.org/obo/HP_0002180
T84 49421-49446 Phenotype denotes increased plasma ferritin http://purl.obolibrary.org/obo/HP_0003281
T85 49722-49748 Phenotype denotes neurodegenerative diseases http://purl.obolibrary.org/obo/HP_0002180
T86 50353-50365 Phenotype denotes dyslipidemia http://purl.obolibrary.org/obo/HP_0003119
T87 50774-50793 Phenotype denotes Alzheimer’s disease http://purl.obolibrary.org/obo/HP_0002511
T88 51875-51890 Phenotype denotes hepatic failure http://purl.obolibrary.org/obo/HP_0001399
T89 52119-52138 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T90 52388-52400 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T91 52544-52552 Phenotype denotes coughing http://purl.obolibrary.org/obo/HP_0012735
T92 52557-52564 Phenotype denotes dyspnea http://purl.obolibrary.org/obo/HP_0002094
T93 56490-56498 Phenotype denotes acidosis http://purl.obolibrary.org/obo/HP_0001941
T94 57810-57836 Phenotype denotes increase of blood pressure http://purl.obolibrary.org/obo/HP_0032263
T95 58527-58538 Phenotype denotes bradycardia http://purl.obolibrary.org/obo/HP_0001662
T96 58628-58639 Phenotype denotes albuminuria http://purl.obolibrary.org/obo/HP_0012592
T97 59688-59709 Phenotype denotes myocardial infarction http://purl.obolibrary.org/obo/HP_0001658
T98 60136-60157 Phenotype denotes myocardial infarction http://purl.obolibrary.org/obo/HP_0001658
T99 60553-60560 Phenotype denotes colitis http://purl.obolibrary.org/obo/HP_0002583
T100 64548-64555 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T101 64821-64849 Phenotype denotes gastrointestinal haemorrhage http://purl.obolibrary.org/obo/HP_0002239
T102 64851-64862 Phenotype denotes arrhythmias http://purl.obolibrary.org/obo/HP_0011675
T103 64864-64870 Phenotype denotes tetany http://purl.obolibrary.org/obo/HP_0001281
T104 64872-64885 Phenotype denotes hypocalcaemia http://purl.obolibrary.org/obo/HP_0002901
T105 64887-64898 Phenotype denotes hypotension http://purl.obolibrary.org/obo/HP_0002615
T106 64913-64931 Phenotype denotes respiratory arrest http://purl.obolibrary.org/obo/HP_0005943
T107 64937-64952 Phenotype denotes agranulocytosis http://purl.obolibrary.org/obo/HP_0012234
T108 67753-67757 Phenotype denotes pain http://purl.obolibrary.org/obo/HP_0012531
T109 70075-70087 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T110 70331-70343 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T111 70903-70915 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T112 70927-70939 Phenotype denotes dyslipidemia http://purl.obolibrary.org/obo/HP_0003119
T113 75063-75069 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T114 75315-75338 Phenotype denotes cardiovascular diseases http://purl.obolibrary.org/obo/HP_0001626
T115 75344-75370 Phenotype denotes inflammatory bowel disease http://purl.obolibrary.org/obo/HP_0002037
T116 75544-75563 Phenotype denotes atrial fibrillation http://purl.obolibrary.org/obo/HP_0005110
T117 75692-75704 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T118 76734-76756 Phenotype denotes chronic kidney disease http://purl.obolibrary.org/obo/HP_0012622
T119 76787-76809 Phenotype denotes cardiovascular disease http://purl.obolibrary.org/obo/HP_0001626
T120 76948-76959 Phenotype denotes proteinuria http://purl.obolibrary.org/obo/HP_0000093
T121 77026-77048 Phenotype denotes chronic kidney disease http://purl.obolibrary.org/obo/HP_0012622
T122 77543-77556 Phenotype denotes hyperactivity http://purl.obolibrary.org/obo/HP_0000752
T123 77760-77788 Phenotype denotes predisposition to infections http://purl.obolibrary.org/obo/HP_0002719
T124 78169-78181 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T125 78183-78195 Phenotype denotes dyslipidemia http://purl.obolibrary.org/obo/HP_0003119
T126 78197-78212 Phenotype denotes type 2 diabetes http://purl.obolibrary.org/obo/HP_0005978
T127 78580-78603 Phenotype denotes obstructive sleep apnea http://purl.obolibrary.org/obo/HP_0002870
T128 78605-78608 Phenotype denotes OSA http://purl.obolibrary.org/obo/HP_0002870
T129 78653-78656 Phenotype denotes OSA http://purl.obolibrary.org/obo/HP_0002870
T130 78717-78720 Phenotype denotes OSA http://purl.obolibrary.org/obo/HP_0002870
T131 78787-78790 Phenotype denotes OSA http://purl.obolibrary.org/obo/HP_0002870
T132 78844-78847 Phenotype denotes OSA http://purl.obolibrary.org/obo/HP_0002870
T133 78900-78905 Phenotype denotes apnea http://purl.obolibrary.org/obo/HP_0002104
T134 78906-78914 Phenotype denotes hypopnea http://purl.obolibrary.org/obo/HP_0040213
T135 78982-78994 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T136 78996-79018 Phenotype denotes cardiovascular disease http://purl.obolibrary.org/obo/HP_0001626
T137 79030-79037 Phenotype denotes obesity http://purl.obolibrary.org/obo/HP_0001513
T138 79185-79192 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T139 79255-79258 Phenotype denotes OSA http://purl.obolibrary.org/obo/HP_0002870
T140 79331-79334 Phenotype denotes OSA http://purl.obolibrary.org/obo/HP_0002870
T141 79555-79558 Phenotype denotes OSA http://purl.obolibrary.org/obo/HP_0002870
T142 82196-82202 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T143 82521-82527 Phenotype denotes asthma http://purl.obolibrary.org/obo/HP_0002099
T144 82624-82638 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T145 82925-82936 Phenotype denotes tachycardia http://purl.obolibrary.org/obo/HP_0001649
T146 82944-82955 Phenotype denotes hypotension http://purl.obolibrary.org/obo/HP_0002615
T147 82979-82986 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T148 83092-83099 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T149 86892-86903 Phenotype denotes hypotension http://purl.obolibrary.org/obo/HP_0002615
T150 86999-87019 Phenotype denotes Respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T151 87060-87091 Phenotype denotes pulmonary arterial hypertension http://purl.obolibrary.org/obo/HP_0002092
T152 87140-87160 Phenotype denotes Respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T153 87327-87336 Phenotype denotes hypoxemia http://purl.obolibrary.org/obo/HP_0012418
T154 87392-87402 Phenotype denotes aspiration http://purl.obolibrary.org/obo/HP_0002835
T155 87404-87410 Phenotype denotes sepsis http://purl.obolibrary.org/obo/HP_0100806
T156 87420-87438 Phenotype denotes acute pancreatitis http://purl.obolibrary.org/obo/HP_0001735
T157 87443-87453 Phenotype denotes pneumonias http://purl.obolibrary.org/obo/HP_0002090
T158 94205-94229 Phenotype denotes coronary atherosclerosis http://purl.obolibrary.org/obo/HP_0001677
T159 95488-95495 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T160 96002-96009 Phenotype denotes colitis http://purl.obolibrary.org/obo/HP_0002583
T161 97427-97438 Phenotype denotes hypercapnia http://purl.obolibrary.org/obo/HP_0012416
T162 99170-99196 Phenotype denotes Inflammatory bowel disease http://purl.obolibrary.org/obo/HP_0002037
T163 99198-99207 Phenotype denotes gastritis http://purl.obolibrary.org/obo/HP_0005263
T164 99212-99219 Phenotype denotes colitis http://purl.obolibrary.org/obo/HP_0002583
T165 102683-102695 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T166 102893-102900 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T167 103064-103077 Phenotype denotes hyperactivity http://purl.obolibrary.org/obo/HP_0000752
T168 103794-103807 Phenotype denotes hyperactivity http://purl.obolibrary.org/obo/HP_0000752
T169 104106-104113 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T170 104614-104621 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T171 104626-104641 Phenotype denotes cardiac failure http://purl.obolibrary.org/obo/HP_0001635
T172 104696-104710 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T173 109560-109571 Phenotype denotes hypotension http://purl.obolibrary.org/obo/HP_0002615

2_test

Id Subject Object Predicate Lexical cue
32708755-32077115-20678617 620-621 32077115 denotes 1
32708755-32161940-20678618 622-623 32161940 denotes 2
32708755-32171076-20678619 624-625 32171076 denotes 3
32708755-32109013-20678620 628-629 32109013 denotes 5
32708755-32294485-20678621 630-631 32294485 denotes 6
32708755-32091533-20678622 632-633 32091533 denotes 7
32708755-31986264-20678623 634-635 31986264 denotes 8
32708755-32297671-20678624 636-637 32297671 denotes 9
32708755-32077115-20678625 904-905 32077115 denotes 1
32708755-32077115-20678626 1144-1145 32077115 denotes 1
32708755-32161940-20678627 1146-1147 32161940 denotes 2
32708755-32171076-20678628 1148-1149 32171076 denotes 3
32708755-32109013-20678629 1152-1153 32109013 denotes 5
32708755-32294485-20678630 1154-1155 32294485 denotes 6
32708755-32091533-20678631 1156-1157 32091533 denotes 7
32708755-31986264-20678632 1158-1159 31986264 denotes 8
32708755-32297671-20678633 1160-1161 32297671 denotes 9
32708755-32294485-20678634 1428-1429 32294485 denotes 6
32708755-32077115-20678635 1509-1510 32077115 denotes 1
32708755-32161940-20678636 1511-1512 32161940 denotes 2
32708755-32171076-20678637 1513-1514 32171076 denotes 3
32708755-32109013-20678638 1517-1518 32109013 denotes 5
32708755-32091533-20678639 1519-1520 32091533 denotes 7
32708755-31986264-20678640 1521-1522 31986264 denotes 8
32708755-32297671-20678641 1523-1524 32297671 denotes 9
32708755-32294485-20678642 1611-1612 32294485 denotes 6
32708755-31230828-20678643 1633-1635 31230828 denotes 10
32708755-32077115-20678644 1715-1716 32077115 denotes 1
32708755-29449338-20678645 2266-2268 29449338 denotes 11
32708755-32077115-20678646 2692-2693 32077115 denotes 1
32708755-32161940-20678647 2694-2695 32161940 denotes 2
32708755-32171076-20678648 2696-2697 32171076 denotes 3
32708755-32109013-20678649 2700-2701 32109013 denotes 5
32708755-32294485-20678650 2702-2703 32294485 denotes 6
32708755-32091533-20678651 2704-2705 32091533 denotes 7
32708755-31986264-20678652 2706-2707 31986264 denotes 8
32708755-32297671-20678653 2708-2709 32297671 denotes 9
32708755-22386035-20678654 2781-2783 22386035 denotes 12
32708755-32142651-20678655 3103-3105 32142651 denotes 13
32708755-16007097-20678656 3297-3299 16007097 denotes 14
32708755-16007097-20678657 3479-3481 16007097 denotes 14
32708755-16001071-20678658 3482-3484 16001071 denotes 15
32708755-18490652-20678659 3933-3935 18490652 denotes 17
32708755-19864379-20678660 3936-3938 19864379 denotes 18
32708755-18490652-20678661 4022-4024 18490652 denotes 17
32708755-19864379-20678662 4025-4027 19864379 denotes 18
32708755-32161940-20678663 4169-4170 32161940 denotes 2
32708755-18490652-20678664 4453-4455 18490652 denotes 17
32708755-18490652-20678665 4800-4802 18490652 denotes 17
32708755-15367630-20678666 4803-4805 15367630 denotes 19
32708755-19995578-20678667 4806-4808 19995578 denotes 20
32708755-18490652-20678668 4998-5000 18490652 denotes 17
32708755-15367630-20678669 5092-5094 15367630 denotes 19
32708755-16510163-20678670 5095-5097 16510163 denotes 21
32708755-19700132-20678671 5349-5351 19700132 denotes 22
32708755-16461478-20678672 5533-5535 16461478 denotes 23
32708755-18490652-20678673 5664-5666 18490652 denotes 17
32708755-15791205-20678674 5667-5669 15791205 denotes 24
32708755-32142651-20678675 6648-6650 32142651 denotes 13
32708755-32142651-20678676 6804-6806 32142651 denotes 13
32708755-30102747-20678677 8244-8246 30102747 denotes 26
32708755-32075877-20678678 8345-8347 32075877 denotes 27
32708755-32132184-20678679 8348-8350 32132184 denotes 28
32708755-32132184-20678680 8541-8543 32132184 denotes 28
32708755-32132184-20678681 8679-8681 32132184 denotes 28
32708755-17522231-20678682 9658-9660 17522231 denotes 29
32708755-32107119-20678683 11109-11111 32107119 denotes 30
32708755-32107119-20678684 11255-11257 32107119 denotes 30
32708755-32107119-20678685 11532-11534 32107119 denotes 30
32708755-32065055-20678686 12166-12168 32065055 denotes 32
32708755-32366817-20678687 12169-12171 32366817 denotes 33
32708755-32065055-20678688 12768-12770 32065055 denotes 32
32708755-32366817-20678689 12771-12773 32366817 denotes 33
32708755-32404477-20678690 12774-12776 32404477 denotes 34
32708755-32253318-20678691 12780-12782 32253318 denotes 36
32708755-32243945-20678692 12783-12785 32243945 denotes 37
32708755-27082314-20678693 13484-13486 27082314 denotes 38
32708755-29434591-20678694 13490-13492 29434591 denotes 40
32708755-30554115-20678695 13493-13495 30554115 denotes 41
32708755-31427727-20678696 13496-13498 31427727 denotes 42
32708755-20599443-20678697 13502-13504 20599443 denotes 44
32708755-23249272-20678698 13505-13507 23249272 denotes 45
32708755-19404405-20678699 14803-14805 19404405 denotes 47
32708755-19700132-20678700 15132-15134 19700132 denotes 22
32708755-23630610-20678701 15135-15137 23630610 denotes 49
32708755-12967627-20678702 15396-15398 12967627 denotes 50
32708755-19221212-20678703 15545-15547 19221212 denotes 51
32708755-20797602-20678704 15939-15941 20797602 denotes 52
32708755-31427727-20678705 16397-16399 31427727 denotes 42
32708755-23884911-20678706 16452-16454 23884911 denotes 53
32708755-20975035-20678707 16634-16636 20975035 denotes 54
32708755-16166274-20678708 17281-17283 16166274 denotes 55
32708755-16166274-20678709 17381-17383 16166274 denotes 55
32708755-24147777-20678710 17473-17475 24147777 denotes 56
32708755-30989646-20678711 17677-17679 30989646 denotes 57
32708755-25194138-20678712 18682-18684 25194138 denotes 60
32708755-2118838-20678713 19097-19099 2118838 denotes 62
32708755-9546381-20678714 19342-19344 9546381 denotes 63
32708755-21874245-20678715 19486-19488 21874245 denotes 64
32708755-27660028-20678716 20188-20190 27660028 denotes 65
32708755-24505094-20678717 20442-20444 24505094 denotes 66
32708755-24168260-20678718 20596-20598 24168260 denotes 67
32708755-24168260-20678719 20870-20872 24168260 denotes 67
32708755-16007097-20678720 21731-21733 16007097 denotes 14
32708755-16001071-20678721 21734-21736 16001071 denotes 15
32708755-29434591-20678722 22270-22272 29434591 denotes 40
32708755-22339213-20678723 22542-22544 22339213 denotes 68
32708755-23889691-20678724 22684-22686 23889691 denotes 69
32708755-23488800-20678725 22774-22776 23488800 denotes 70
32708755-23547236-20678726 22895-22897 23547236 denotes 71
32708755-29616018-20678727 23089-23091 29616018 denotes 72
32708755-29616018-20678728 23248-23250 29616018 denotes 72
32708755-10749743-20678729 23450-23452 10749743 denotes 73
32708755-32161940-20678730 23594-23595 32161940 denotes 2
32708755-31986264-20678731 23596-23597 31986264 denotes 8
32708755-32297671-20678732 23598-23599 32297671 denotes 9
32708755-17303661-20678733 24168-24170 17303661 denotes 74
32708755-15897343-20678734 24529-24531 15897343 denotes 75
32708755-18849338-20678735 24780-24782 18849338 denotes 76
32708755-18849338-20678736 25132-25134 18849338 denotes 76
32708755-18768926-20678737 25135-25137 18768926 denotes 77
32708755-32075877-20678738 26893-26895 32075877 denotes 27
32708755-32065055-20678739 26896-26898 32065055 denotes 32
32708755-15791205-20678740 26998-27000 15791205 denotes 24
32708755-19901337-20678741 27155-27157 19901337 denotes 78
32708755-18490652-20678742 27387-27389 18490652 denotes 17
32708755-32142651-20678743 27683-27685 32142651 denotes 13
32708755-32161940-20678744 27762-27763 32161940 denotes 2
32708755-24147777-20678745 28112-28114 24147777 denotes 56
32708755-18490652-20678746 28402-28404 18490652 denotes 17
32708755-18490652-20678747 28664-28666 18490652 denotes 17
32708755-32142651-20678748 33326-33328 32142651 denotes 13
32708755-19995578-20678749 33444-33446 19995578 denotes 20
32708755-23488800-20678750 35104-35106 23488800 denotes 70
32708755-28018220-20678751 35447-35449 28018220 denotes 81
32708755-19948988-20678752 35826-35828 19948988 denotes 82
32708755-20713916-20678753 36020-36022 20713916 denotes 83
32708755-20713916-20678754 36293-36295 20713916 denotes 83
32708755-30913349-20678755 36450-36452 30913349 denotes 84
32708755-27730696-20678756 36667-36669 27730696 denotes 85
32708755-10969042-20678757 37459-37461 10969042 denotes 86
32708755-10924499-20678758 37462-37464 10924499 denotes 87
32708755-10969042-20678759 37580-37582 10969042 denotes 86
32708755-10924499-20678760 37583-37585 10924499 denotes 87
32708755-20599443-20678761 37769-37771 20599443 denotes 44
32708755-20599443-20678762 37871-37873 20599443 denotes 44
32708755-23249272-20678763 37874-37876 23249272 denotes 45
32708755-18849338-20678764 37880-37882 18849338 denotes 76
32708755-18768926-20678765 37883-37885 18768926 denotes 77
32708755-10924499-20678766 37886-37888 10924499 denotes 87
32708755-16007097-20678767 38069-38071 16007097 denotes 14
32708755-20599443-20678768 38075-38077 20599443 denotes 44
32708755-23249272-20678769 38078-38080 23249272 denotes 45
32708755-18849338-20678770 38084-38086 18849338 denotes 76
32708755-18768926-20678771 38087-38089 18768926 denotes 77
32708755-10924499-20678772 38090-38092 10924499 denotes 87
32708755-18022664-20678773 38093-38095 18022664 denotes 88
32708755-16306622-20678774 38096-38098 16306622 denotes 89
32708755-16007097-20678775 38372-38374 16007097 denotes 14
32708755-20599443-20678776 38375-38377 20599443 denotes 44
32708755-23249272-20678777 38378-38380 23249272 denotes 45
32708755-10969042-20678778 38384-38386 10969042 denotes 86
32708755-10924499-20678779 38387-38389 10924499 denotes 87
32708755-18022664-20678780 38390-38392 18022664 denotes 88
32708755-16306622-20678781 38393-38395 16306622 denotes 89
32708755-20599443-20678782 39027-39029 20599443 denotes 44
32708755-32109013-20678783 39200-39201 32109013 denotes 5
32708755-30266430-20678784 39486-39488 30266430 denotes 91
32708755-32294485-20678785 39776-39777 32294485 denotes 6
32708755-31986264-20678786 39778-39779 31986264 denotes 8
32708755-24505094-20678787 39780-39782 24505094 denotes 66
32708755-30845246-20678788 39783-39785 30845246 denotes 92
32708755-30266430-20678789 40174-40176 30266430 denotes 91
32708755-21827444-20678790 40227-40229 21827444 denotes 93
32708755-28570269-20678791 40230-40232 28570269 denotes 94
32708755-21827444-20678792 40509-40511 21827444 denotes 93
32708755-31426452-20678793 40945-40947 31426452 denotes 95
32708755-31426452-20678794 41069-41071 31426452 denotes 95
32708755-31426452-20678795 41219-41221 31426452 denotes 95
32708755-32294485-20678796 41744-41745 32294485 denotes 6
32708755-31986264-20678797 41746-41747 31986264 denotes 8
32708755-25813276-20678798 42183-42185 25813276 denotes 96
32708755-28953660-20678799 43060-43063 28953660 denotes 100
32708755-20617034-20678800 43068-43071 20617034 denotes 102
32708755-32276440-20678801 43552-43555 32276440 denotes 103
32708755-30718726-20678802 43556-43559 30718726 denotes 104
32708755-32276440-20678803 43742-43745 32276440 denotes 103
32708755-32161940-20678804 43827-43828 32161940 denotes 2
32708755-31986264-20678805 43829-43830 31986264 denotes 8
32708755-32297671-20678806 43831-43832 32297671 denotes 9
32708755-32276440-20678807 44015-44018 32276440 denotes 103
32708755-20617034-20678808 44183-44186 20617034 denotes 102
32708755-32408070-20678809 44271-44274 32408070 denotes 107
32708755-20617034-20678810 44330-44333 20617034 denotes 102
32708755-30718726-20678811 44547-44550 30718726 denotes 104
32708755-29903860-20678812 44761-44764 29903860 denotes 108
32708755-20713898-20678813 44765-44768 20713898 denotes 109
32708755-18832706-20678814 44769-44772 18832706 denotes 110
32708755-32276440-20678815 44963-44966 32276440 denotes 103
32708755-30718726-20678816 44967-44970 30718726 denotes 104
32708755-28717982-20678817 45572-45575 28717982 denotes 111
32708755-28717982-20678818 45870-45873 28717982 denotes 111
32708755-28717982-20678819 46075-46078 28717982 denotes 111
32708755-28717982-20678820 46587-46590 28717982 denotes 111
32708755-32132184-20678821 46862-46864 32132184 denotes 28
32708755-30266430-20678822 47006-47008 30266430 denotes 91
32708755-30266430-20678823 47948-47950 30266430 denotes 91
32708755-30266430-20678824 48124-48126 30266430 denotes 91
32708755-20617034-20678825 48127-48130 20617034 denotes 102
32708755-30266430-20678826 48893-48895 30266430 denotes 91
32708755-30266430-20678827 49120-49122 30266430 denotes 91
32708755-32161940-20678828 49476-49477 32161940 denotes 2
32708755-32171076-20678829 49478-49479 32171076 denotes 3
32708755-32294485-20678830 49480-49481 32294485 denotes 6
32708755-20617034-20678831 49750-49753 20617034 denotes 102
32708755-30266430-20678832 50116-50118 30266430 denotes 91
32708755-30266430-20678833 50229-50231 30266430 denotes 91
32708755-30266430-20678834 50795-50797 30266430 denotes 91
32708755-30266430-20678835 50909-50911 30266430 denotes 91
32708755-30266430-20678836 51031-51033 30266430 denotes 91
32708755-28953660-20678837 51584-51587 28953660 denotes 100
32708755-20617034-20678838 51592-51595 20617034 denotes 102
32708755-28953660-20678839 51706-51709 28953660 denotes 100
32708755-28953660-20678840 51893-51896 28953660 denotes 100
32708755-28953660-20678841 52077-52080 28953660 denotes 100
32708755-28953660-20678842 52177-52180 28953660 denotes 100
32708755-32132184-20678843 53105-53107 32132184 denotes 28
32708755-15791205-20678844 53672-53674 15791205 denotes 24
32708755-32132184-20678845 53856-53858 32132184 denotes 28
32708755-32132184-20678846 53923-53925 32132184 denotes 28
32708755-18490652-20678847 54355-54357 18490652 denotes 17
32708755-15791205-20678848 54358-54360 15791205 denotes 24
32708755-15791205-20678849 54626-54628 15791205 denotes 24
32708755-15791205-20678850 54829-54831 15791205 denotes 24
32708755-12358520-20678851 55045-55048 12358520 denotes 113
32708755-26851370-20678852 55049-55052 26851370 denotes 114
32708755-26851370-20678853 55139-55142 26851370 denotes 114
32708755-26851370-20678854 55325-55328 26851370 denotes 114
32708755-26851370-20678855 55676-55679 26851370 denotes 114
32708755-26851370-20678856 56043-56046 26851370 denotes 114
32708755-26851370-20678857 56143-56146 26851370 denotes 114
32708755-22777933-20678858 56374-56377 22777933 denotes 115
32708755-22777933-20678859 56859-56862 22777933 denotes 115
32708755-18223027-20678860 57358-57361 18223027 denotes 116
32708755-32132184-20678861 57487-57489 32132184 denotes 28
32708755-18235039-20678862 58045-58048 18235039 denotes 117
32708755-20300067-20678863 58168-58171 20300067 denotes 118
32708755-20599443-20678864 58548-58550 20599443 denotes 44
32708755-17579661-20678865 58783-58786 17579661 denotes 119
32708755-26851370-20678866 59332-59335 26851370 denotes 114
32708755-22777933-20678867 59336-59339 22777933 denotes 115
32708755-20797602-20678868 60066-60068 20797602 denotes 52
32708755-19517214-20678869 60562-60565 19517214 denotes 122
32708755-20717537-20678870 61146-61149 20717537 denotes 123
32708755-20717537-20678871 61748-61751 20717537 denotes 123
32708755-20617034-20678872 62078-62081 20617034 denotes 102
32708755-32132184-20678873 63321-63323 32132184 denotes 28
32708755-25271834-20678874 63645-63648 25271834 denotes 124
32708755-30266430-20678875 63859-63861 30266430 denotes 91
32708755-30316994-20678876 63966-63969 30316994 denotes 125
32708755-31171812-20678877 64169-64172 31171812 denotes 126
32708755-20717537-20678878 65000-65003 20717537 denotes 123
32708755-20717537-20678879 65168-65171 20717537 denotes 123
32708755-20717537-20678880 65259-65262 20717537 denotes 123
32708755-18223027-20678881 65713-65716 18223027 denotes 116
32708755-18223027-20678882 65968-65971 18223027 denotes 116
32708755-15492138-20678883 66765-66768 15492138 denotes 127
32708755-15492138-20678884 66942-66945 15492138 denotes 127
32708755-23769988-20678885 67405-67408 23769988 denotes 128
32708755-27082314-20678886 67559-67561 27082314 denotes 38
32708755-30554115-20678887 67565-67567 30554115 denotes 41
32708755-28717982-20678888 68045-68048 28717982 denotes 111
32708755-26106051-20678889 68303-68306 26106051 denotes 130
32708755-29387012-20678890 68969-68972 29387012 denotes 131
32708755-15367630-20678891 69110-69112 15367630 denotes 19
32708755-16510163-20678892 69113-69115 16510163 denotes 21
32708755-29903860-20678893 69422-69425 29903860 denotes 108
32708755-32333836-20678894 69426-69429 32333836 denotes 133
32708755-28877748-20678895 69430-69433 28877748 denotes 134
32708755-29903860-20678896 69812-69815 29903860 denotes 108
32708755-28877748-20678897 69816-69819 28877748 denotes 134
32708755-32077115-20678898 70120-70121 32077115 denotes 1
32708755-32161940-20678899 70122-70123 32161940 denotes 2
32708755-32171076-20678900 70124-70125 32171076 denotes 3
32708755-32109013-20678901 70128-70129 32109013 denotes 5
32708755-32294485-20678902 70130-70131 32294485 denotes 6
32708755-32091533-20678903 70132-70133 32091533 denotes 7
32708755-31986264-20678904 70134-70135 31986264 denotes 8
32708755-32297671-20678905 70136-70137 32297671 denotes 9
32708755-29449338-20678906 70513-70515 29449338 denotes 11
32708755-25813276-20678907 70752-70754 25813276 denotes 96
32708755-25813276-20678908 70871-70873 25813276 denotes 96
32708755-25813276-20678909 71063-71065 25813276 denotes 96
32708755-32171062-20678910 71266-71269 32171062 denotes 135
32708755-32222168-20678911 71270-71273 32222168 denotes 136
32708755-32222169-20678912 71274-71277 32222169 denotes 137
32708755-32665962-20678913 71278-71281 32665962 denotes 138
32708755-25813276-20678914 71565-71567 25813276 denotes 96
32708755-15897343-20678915 71721-71723 15897343 denotes 75
32708755-15897343-20678916 71932-71934 15897343 denotes 75
32708755-32294485-20678917 73094-73095 32294485 denotes 6
32708755-32356628-20678918 73112-73115 32356628 denotes 143
32708755-32228222-20678919 73343-73346 32228222 denotes 145
32708755-32474043-20678920 73347-73350 32474043 denotes 146
32708755-32422341-20678921 73351-73354 32422341 denotes 147
32708755-32302265-20678922 73355-73358 32302265 denotes 148
32708755-32474043-20678923 73683-73686 32474043 denotes 146
32708755-25813276-20678924 74758-74760 25813276 denotes 96
32708755-31989052-20678925 75015-75018 31989052 denotes 149
32708755-21895524-20678926 75019-75022 21895524 denotes 150
32708755-19700132-20678927 75408-75410 19700132 denotes 22
32708755-23630610-20678928 75411-75413 23630610 denotes 49
32708755-29897923-20678929 75414-75417 29897923 denotes 151
32708755-27738071-20678930 75418-75421 27738071 denotes 152
32708755-27738071-20678931 75738-75741 27738071 denotes 152
32708755-32077115-20678932 76585-76586 32077115 denotes 1
32708755-32161940-20678933 76587-76588 32161940 denotes 2
32708755-32171076-20678934 76589-76590 32171076 denotes 3
32708755-32109013-20678935 76593-76594 32109013 denotes 5
32708755-32294485-20678936 76595-76596 32294485 denotes 6
32708755-32091533-20678937 76597-76598 32091533 denotes 7
32708755-31986264-20678938 76599-76600 31986264 denotes 8
32708755-32297671-20678939 76601-76602 32297671 denotes 9
32708755-22386035-20678940 76646-76648 22386035 denotes 12
32708755-25813276-20678941 76934-76936 25813276 denotes 96
32708755-30554115-20678942 77490-77492 30554115 denotes 41
32708755-24842388-20678943 77493-77496 24842388 denotes 154
32708755-32665962-20678944 78011-78014 32665962 denotes 138
32708755-30227878-20678945 78015-78018 30227878 denotes 155
32708755-30675038-20678946 78019-78022 30675038 denotes 156
32708755-30335025-20678947 78027-78030 30335025 denotes 158
32708755-16283142-20678948 78031-78034 16283142 denotes 159
32708755-27310975-20678949 78035-78038 27310975 denotes 160
32708755-30917908-20678950 78039-78042 30917908 denotes 161
32708755-32133153-20678951 78043-78046 32133153 denotes 162
32708755-32170560-20678952 78047-78050 32170560 denotes 163
32708755-32665962-20678953 78245-78248 32665962 denotes 138
32708755-30227878-20678954 78249-78252 30227878 denotes 155
32708755-30675038-20678955 78253-78256 30675038 denotes 156
32708755-30335025-20678956 78261-78264 30335025 denotes 158
32708755-16283142-20678957 78265-78268 16283142 denotes 159
32708755-27310975-20678958 78269-78272 27310975 denotes 160
32708755-30917908-20678959 78273-78276 30917908 denotes 161
32708755-32665962-20678960 78518-78521 32665962 denotes 138
32708755-32342265-20678961 78671-78674 32342265 denotes 164
32708755-31694839-20678962 79065-79068 31694839 denotes 167
32708755-31694839-20678963 79667-79670 31694839 denotes 167
32708755-32555424-20678964 80754-80757 32555424 denotes 170
32708755-32505227-20678965 80762-80765 32505227 denotes 172
32708755-32065055-20678966 81747-81749 32065055 denotes 32
32708755-32366817-20678967 81750-81752 32366817 denotes 33
32708755-32404477-20678968 81753-81755 32404477 denotes 34
32708755-32253318-20678969 81759-81761 32253318 denotes 36
32708755-32243945-20678970 81762-81764 32243945 denotes 37
32708755-32505227-20678971 81765-81768 32505227 denotes 172
32708755-21937658-20678972 82360-82363 21937658 denotes 176
32708755-18832706-20678973 82856-82859 18832706 denotes 110
32708755-32171076-20678974 83590-83591 32171076 denotes 3
32708755-18223027-20678975 85060-85063 18223027 denotes 116
32708755-25813276-20678976 85139-85141 25813276 denotes 96
32708755-22777933-20678977 86104-86107 22777933 denotes 115
32708755-22777933-20678978 86293-86296 22777933 denotes 115
32708755-22777933-20678979 86416-86419 22777933 denotes 115
32708755-32048163-20678980 86711-86714 32048163 denotes 177
32708755-20599443-20678981 87657-87659 20599443 denotes 44
32708755-16001071-20678982 87747-87749 16001071 denotes 15
32708755-28877748-20678983 87835-87838 28877748 denotes 134
32708755-23681967-20678984 87964-87967 23681967 denotes 178
32708755-28877748-20678985 88039-88042 28877748 denotes 134
32708755-29903860-20678986 88091-88094 29903860 denotes 108
32708755-30845246-20678987 88504-88506 30845246 denotes 92
32708755-25107336-20678988 88738-88741 25107336 denotes 179
32708755-25107336-20678989 89036-89039 25107336 denotes 179
32708755-25107336-20678990 89384-89387 25107336 denotes 179
32708755-25107336-20678991 89472-89475 25107336 denotes 179
32708755-25107336-20678992 89868-89871 25107336 denotes 179
32708755-2170511-20678993 90203-90206 2170511 denotes 180
32708755-2170511-20678994 90368-90371 2170511 denotes 180
32708755-30845246-20678995 90822-90824 30845246 denotes 92
32708755-28877748-20678996 91025-91028 28877748 denotes 134
32708755-30845246-20678997 91209-91211 30845246 denotes 92
32708755-28877748-20678998 91212-91215 28877748 denotes 134
32708755-28877748-20678999 91368-91371 28877748 denotes 134
32708755-28877748-20679000 91419-91422 28877748 denotes 134
32708755-30845246-20679001 91796-91798 30845246 denotes 92
32708755-25107336-20679002 92212-92215 25107336 denotes 179
32708755-2170511-20679003 92216-92219 2170511 denotes 180
32708755-22777933-20679004 92298-92301 22777933 denotes 115
32708755-22518284-20679005 92302-92305 22518284 denotes 181
32708755-30845246-20679006 92398-92400 30845246 denotes 92
32708755-23681967-20679007 92866-92869 23681967 denotes 178
32708755-25107336-20679008 92870-92873 25107336 denotes 179
32708755-30845246-20679009 92976-92978 30845246 denotes 92
32708755-22777933-20679010 93391-93394 22777933 denotes 115
32708755-25107336-20679011 93395-93398 25107336 denotes 179
32708755-22518284-20679012 93399-93402 22518284 denotes 181
32708755-23681967-20679013 93720-93723 23681967 denotes 178
32708755-28877748-20679014 93744-93747 28877748 denotes 134
32708755-30845246-20679015 94062-94064 30845246 denotes 92
32708755-29903860-20679016 94349-94352 29903860 denotes 108
32708755-27432541-20679017 94353-94356 27432541 denotes 182
32708755-27432541-20679018 94454-94457 27432541 denotes 182
32708755-29903860-20679019 94670-94673 29903860 denotes 108
32708755-27432541-20679020 94674-94677 27432541 denotes 182
32708755-12358520-20679021 97284-97287 12358520 denotes 113
32708755-22777933-20679022 97410-97413 22777933 denotes 115
32708755-15791205-20679023 97620-97622 15791205 denotes 24
32708755-20797602-20679024 98023-98025 20797602 denotes 52
32708755-18235039-20679025 98026-98029 18235039 denotes 117
32708755-20300067-20679026 98030-98033 20300067 denotes 118
32708755-19517214-20679027 98034-98037 19517214 denotes 122
32708755-23370913-20679028 98038-98041 23370913 denotes 183
32708755-31982938-20679029 98042-98045 31982938 denotes 184
32708755-20797602-20679030 98580-98582 20797602 denotes 52
32708755-23370913-20679031 98583-98586 23370913 denotes 183
32708755-31982938-20679032 98587-98590 31982938 denotes 184
32708755-19517214-20679033 98919-98922 19517214 denotes 122
32708755-19517214-20679034 99004-99007 19517214 denotes 122
32708755-31645418-20679035 100121-100124 31645418 denotes 185
32708755-18223027-20679036 102091-102094 18223027 denotes 116
32708755-27432541-20679037 104817-104820 27432541 denotes 182
32708755-20717537-20679038 105158-105161 20717537 denotes 123
32708755-20717537-20679039 105206-105209 20717537 denotes 123
32708755-20717537-20679040 105833-105836 20717537 denotes 123
32708755-14007184-20679041 106213-106216 14007184 denotes 188
32708755-14007184-20679042 106486-106489 14007184 denotes 188
32708755-14007184-20679043 106631-106634 14007184 denotes 188
32708755-20717537-20679044 107267-107270 20717537 denotes 123
32708755-11149993-20679045 107372-107375 11149993 denotes 191
32708755-20717537-20679046 107848-107851 20717537 denotes 123